Activators & Small Molecules
•Inducers can also activate activators:
–VAI (3-N-oxohexanoyl-L-Homoserine lacton) à luxR
•Use as a logical (AND) gate:
operator
promoter
gene
RNAP
inactive
activator
operator
promoter
gene
RNAP
active
activator
inducer
no transcription
transcription
Inducer
Activator
Output