METABOLISM (1066 ORFs) 01 1066 YAL004W YAL004W strong similarity to A.klebsiana glutamate dehydrogenase YAL012W CYS3 cystathionine gamma-lyase YAL013W DEP1 regulator of phospholipid metabolism YAL021C CCR4 transcriptional regulator YAL022C FUN26 intracellular membrane protein involved in nucleoside transport YAL023C PMT2 mannosyltransferase YAL038W CDC19 pyruvate kinase YAL039C CYC3 holocytochrome-c synthase (cytochrome c heme lyase) YAL044C GCV3 glycine decarboxylase, subunit H YAL051W OAF1 peroxisome proliferating transcription factor YAL054C ACS1 acetyl-CoA synthetase YAL060W BDH1 stereospecific (2R, 3R)-2,3-butanediol dehydrogenase YAL061W FUN50 similarity to alcohol/sorbitol dehydrogenase YAL062W GDH3 NADP-glutamate dehydrogenase YAR015W ADE1 phosphoribosylamidoimidazole-succinocarboxamide synthase YAR035W YAT1 carnitine acetyltransferase, mitochondrial YAR042W SWH1 similarity to mammalian oxysterol-binding proteins YAR044W OSH1 similarity to human oxysterol binding protein (OSBP) YAR071W PHO11 secreted acid phosphatase YAR073W IMD1 strong similarity to IMP dehydrogenases YAR075W YAR075W strong similarity to IMP dehydrogenases YBL001C ECM15 involved in cell wall biogenesis and architecture YBL015W ACH1 acetyl-CoA hydrolase YBL030C PET9 ADP/ATP carrier protein (MCF) YBL033C RIB1 GTP cyclohydrolase II YBL039C URA7 CTP synthase 1 YBL042C FUI1 uridine transport protein YBL061C SKT5 protoplast regeneration and killer toxin resistance protein YBL068W PRS4 ribose-phosphate pyrophosphokinase 3 YBL082C RHK1 mannosyltransferase YBL086C YBL086C weak similarity to S. pombe hypothetical protein YBL088C TEL1 telomere length control protein YBL098W YBL098W similarity to human and D.melanogaster kynurenine 3-monooxygenase YBL103C RTG3 bHLH/zip transcription factor that regulates CIT2 gene expression YBR001C NTH2 alpha,alpha-trehalase YBR003W COQ1 hexaprenyl pyrophosphate synthetase precursor YBR006W UGA2 succinate semialdehyde dehydrogenase YBR011C IPP1 inorganic pyrophosphatase, cytoplasmic YBR014C YBR014C similarity to glutaredoxin YBR018C GAL7 UDP-glucose--hexose-1-phosphate uridylyltransferase YBR019C GAL10 UDP-glucose 4-epimerase YBR020W GAL1 galactokinase YBR021W FUR4 uracil permease YBR023C CHS3 chitin synthase III YBR029C CDS1 CDP-diacylglycerol synthase YBR030W YBR030W weak similarity to regulatory protein MSR1P YBR035C PDX3 pyridoxamine-phosphate oxidase YBR036C CSG2 calcium dependent regulatory protein YBR038W CHS2 chitin synthase II YBR041W FAT1 very long-chain fatty acyl-CoA synthetase YBR042C CST26 weak similarity to 1-acyl-sn-glycerol-3-phosphate acyltransferase from Brassica napus YBR050C REG2 regulatory subunit of type I protein phosphatase YBR056W YBR056W similarity to glucan 1,3-beta-glucosidase YBR058C-A TSC3 required for optimal serine palmitoyltransferase activity YBR067C TIP1 esterase YBR068C BAP2 leucine permease, high-affinity (S1) YBR069C TAT1 amino acid permease YBR084W MIS1 C1-tetrahydrofolate synthase precursor, mitochondrial YBR085W AAC3 ADP/ATP carrier protein (MCF) YBR092C PHO3 constitutive acid phosphatase precursor YBR093C PHO5 repressible acid phosphatase precursor YBR106W PHO88 involved in phosphate transport YBR110W ALG1 beta-mannosyltransferase YBR111C YSA1 sugar-nucleotide hydrolase YBR115C LYS2 L-aminoadipate-semialdehyde dehydrogenase, large subunit YBR117C TKL2 transketolase 2 YBR126C TPS1 alpha,alpha-trehalose-phosphate synthase, 56 KD subunit YBR132C AGP2 amino-acid permease YBR145W ADH5 alcohol dehydrogenase V YBR149W ARA1 D-arabinose dehydrogenase, large subunit YBR153W RIB7 HTP reductase YBR159W YBR159W similarity to human 17-beta-hydroxysteroid dehydrogenase YBR166C TYR1 prephenate dehydrogenase (NADP+) YBR176W ECM31 involved in cell wall biogenesis and architecture YBR183W YPC1 Alkaline Ceramidase YBR196C PGI1 glucose-6-phosphate isomerase YBR199W KTR4 alpha-1,2-mannosyltransferase YBR204C YBR204C weak similarity to peroxisomal serine-active lipase YBR205W KTR3 alpha-1,2-mannosyltransferase YBR208C DUR1,2 urea amidolyase YBR213W MET8 siroheme synthase YBR218C PYC2 pyruvate carboxylase 2 YBR221C PDB1 pyruvate dehydrogenase (lipoamide) beta chain precursor YBR222C FAT2 AMP-binding protein, peroxisomal YBR229C ROT2 glucosidase II, catalytic subunit YBR241C YBR241C similarity to glucose transport proteins YBR243C ALG7 UDP-N-acetylglucosamine-1-phosphate transferase YBR248C HIS7 glutamine amidotransferase/cyclase YBR249C ARO4 2-dehydro-3-deoxyphosphoheptonate aldolase, tyrosine-inhibited YBR252W DUT1 dUTP pyrophosphatase precursor YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR256C RIB5 riboflavin synthase, alpha chain YBR263W SHM1 serine hydroxymethyltransferase precursor, mitochondrial YBR265W TSC10 3-ketosphinganine reductase YBR284W YBR284W similarity to AMP deaminase YBR289W SNF5 component of SWI/SNF transcription activator complex YBR291C CTP1 citrate transport protein, mitochondrial (MCF) YBR294W SUL1 high-affinity sulfate transport protein YBR296C PHO89 Na+-coupled phosphate transport protein, high affinity YBR297W MAL33 maltose fermentation regulatory protein YBR298C MAL31 maltose permease YBR299W MAL32 alpha-glucosidase YCL004W PGS1 phosphatidylglycerophosphate synthase YCL009C ILV6 acetolactate synthase, regulatory subunit YCL018W LEU2 beta-isopropyl-malate dehydrogenase YCL025C AGP1 asparagine and glutamine permease YCL026C-A FRM2 involved in fatty acid regulation YCL030C HIS4 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase/histidinol dehydrogenase YCL040W GLK1 aldohexose specific glucokinase YCL043C PDI1 protein disulfide-isomerase precursor YCL050C APA1 ATP adenylyltransferase I YCL064C CHA1 L-serine/L-threonine deaminase YCR002C CDC10 cell division control protein YCR005C CIT2 citrate (si)-synthase, peroxisomal YCR010C ADY2 strong similarity to Y.lipolytica GPR1 protein and FUN34P YCR012W PGK1 phosphoglycerate kinase YCR028C FEN2 high affinity H+/pantothenate symporter YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR036W RBK1 ribokinase YCR037C PHO87 member of the phosphate permease family YCR048W ARE1 acyl-CoA sterol acyltransferase YCR053W THR4 threonine synthase (o-p-homoserine p-lyase) YCR081W SRB8 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YCR098C GIT1 glycerophosphoinositol transporter YCR105W YCR105W strong similarity to alcohol dehydrogenases YCR107W AAD3 strong similarity aryl-alcohol reductases of P. chrysosporium YDL006W PTC1 protein serine/threonine phosphatase 2c YDL010W YDL010W similarity to hypothetical protein YBR014c and glutaredoxins YDL013W HEX3 hexose metabolism-related protein YDL015C TSC13 required for elongation of the very long chain fatty acid (VLCFA) moiety of sphingolipids YDL019C OSH2 similarity to SWH1P YDL021W GPM2 phosphoglycerate mutase YDL022W GPD1 glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic YDL024C DIA3 strong similarity to acid phosphatase YDL036C YDL036C strong similarity to RIB2 protein YDL037C YDL037C strong similarity to glucan 1,4-alpha-glucosidase YDL040C NAT1 protein N-acetyltransferase subunit YDL045C FAD1 flavin adenine dinucleotide (FAD) synthetase YDL048C STP4 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YDL049C KNH1 functional homolog of KRE9 YDL052C SLC1 fatty acyltransferase YDL055C PSA1 mannose-1-phosphate guanyltransferase YDL066W IDP1 isocitrate dehydrogenase (NADP+), mitochondrial YDL078C MDH3 malate dehydrogenase, peroxisomal YDL080C THI3 positive regulation factor of thiamin metabolism YDL090C RAM1 protein farnesyltransferase, beta subunit YDL093W PMT5 O-mannosyltransferase similarity to PMT1P-PMT4P YDL095W PMT1 mannosyltransferase YDL106C PHO2 homeodomain protein YDL109C YDL109C strong similarity to hypothetical protein YGL144c YDL124W YDL124W similarity to aldose reductases YDL125C HNT1 similarity to protein kinase C inhibitor-I YDL131W LYS21 homocitrate synthase YDL132W CDC53 controls G1/S transition YDL134C PPH21 protein ser/thr phosphatase PP2A-1 YDL138W RGT2 suppressor of SNF3 mutant YDL141W BPL1 biotin holocarboxylase synthetase YDL142C CRD1 cardiolipin synthase YDL168W SFA1 long-chain alcohol dehydrogenase YDL170W UGA3 transcriptional activator for GABA catabolic genes YDL171C GLT1 glutamate synthase (NAPDPH) (GOGAT) YDL174C DLD1 D-lactate ferricytochrome C oxidoreductase (D-LCR) YDL182W LYS20 homocitrate synthase YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL199C YDL199C similarity to sugar transporter proteins YDL203C YDL203C similarity to SKT5P YDL205C HEM3 porphobilinogen deaminase YDL210W UGA4 GABA-specific high-affinity permease YDL215C GDH2 NAD-specific glutamate dehydrogenase (NAD) YDL232W OST4 oligosaccharyltransferase subunit YDL236W PHO13 4-nitrophenylphosphatase YDL243C AAD4 strong similarity to aryl-alcohol dehydrogenase YDL244W THI13 strong similarity to THI5P, YJR156c, YNL332w and A. parasiticus, S.pombe NMT1 protein YDL245C HXT15 strong similarity to HXT17P and HXT7P YDL246C YDL246C strong similarity to SOR1P YDL247W YDL247W strong similarity to sugar transport proteins YDR001C NTH1 neutral trehalase (alpha,alpha-trehalase) YDR007W TRP1 phosphoribosylanthranilate isomerase YDR009W GAL3 galactokinase YDR011W SNQ2 multidrug resistance protein YDR019C GCV1 glycine decarboxylase, subunit T YDR020C YDR020C weak similarity to uridine kinases and phosphoribulokinases YDR028C REG1 regulatory subunit for protein phosphatase GLC7P YDR034C LYS14 transcriptional activator of lysine pathway genes YDR035W ARO3 2-dehydro-3-deoxyphosphoheptonate aldolase, phenylalanine-inhibited YDR043C NRG1 transcriptional repressor for glucose repression of STA1 gene expression YDR044W HEM13 coproporphyrinogen III oxidase YDR046C BAP3 valine transporter YDR047W HEM12 uroporphyrinogen decarboxylase YDR050C TPI1 triose-phosphate isomerase YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR058C TGL2 triacylglycerol lipase YDR062W LCB2 serine C-palmitoyltransferase subunit YDR072C IPT1 mannosyl diphosphorylinositol ceramide synthase YDR073W SNF11 component of SWI/SNF transcription activator complex YDR074W TPS2 alpha,alpha-trehalose-phosphate synthase, 102 KD subunit YDR081C PDC2 pyruvate decarboxylase regulatory protein YDR111C YDR111C strong similarity to alanine transaminase YDR123C INO2 basic helix-loop-helix (BHLH) transcription factor YDR127W ARO1 arom pentafunctional enzyme YDR147W EKI1 ethanolamine kinase YDR148C KGD2 2-oxoglutarate dehydrogenase complex E2 component YDR158W HOM2 aspartate-semialdehyde dehydrogenase YDR159W SAC3 leucine permease transcriptional regulator YDR160W SSY1 transcriptional regulator of several transporter genes YDR173C ARG82 arginine metabolism transcription factor YDR176W NGG1 general transcriptional adaptor or co-activator YDR178W SDH4 succinate dehydrogenase membrane anchor subunit for SDH2P YDR204W COQ4 responsible for restoring ubiquinone biosynthesis in COQ4 mutant YDR207C UME6 negative transcriptional regulator YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR213W UPC2 regulatory protein involved in control of sterol uptake YDR216W ADR1 zinc-finger transcription factor YDR226W ADK1 adenylate kinase, cytosolic YDR232W HEM1 5-aminolevulinate synthase YDR234W LYS4 homoaconitase YDR242W AMD2 amidase YDR245W MNN10 subunit of mannosyltransferase complex YDR248C YDR248C strong similarity to E.coli thermoresistant gluconokinase YDR253C MET32 transcriptional regulator of sulfur amino acid metabolism YDR261C EXG2 exo-beta-1,3-glucanase minor isoform YDR272W GLO2 glyoxalase II (hydroxyacylglutathione hydrolase) YDR277C MTH1 repressor of hexose transport genes YDR284C DPP1 diacylglycerol pyrophosphate phosphatase YDR287W YDR287W similarity to inositolmonophosphatases YDR294C DPL1 dihydrosphingosine phosphate lyase YDR297W SUR2 required for the hydroxylation of C-4 of the sphingoid moiety of ceramide YDR300C PRO1 glutamate 5-kinase YDR302W GPI11 GPI11 - protein involved in glycosylphosphatidylinositol (GPI) biosynthesis YDR305C HNT2 dinucleoside 5',5 YDR307W YDR307W similarity to PMT1P, PMT2P, PMT3P and PMT5P YDR313C PIB1 phosphatidylinositol(3)-phosphate binding protein YDR321W ASP1 asparaginase YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR331W GPI8 essential for GPI anchor attachment YDR342C HXT7 high-affinity hexose transporter YDR343C HXT6 high-affinity hexose transporter YDR345C HXT3 low-affinity hexose transporter YDR353W TRR1 thioredoxin reductase (NADPH) YDR354W TRP4 anthranilate phosphoribosyltransferase YDR368W YPR1 strong similarity to members of the aldo/keto reductase family YDR371W YDR371W similarity to chitinases YDR376W ARH1 mitochondrial protein with similarity to human adrenodoxin reductase and ferredoxin-NADP+ reductase YDR380W ARO10 similarity to PDC6P, THI3P and to pyruvate decarboxylases YDR384C YDR384C strong similarity to Y.lipolytica GPR1 gene YDR387C YDR387C similarity to ITR1P and ITR2P and E.coli araE YDR399W HPT1 hypoxanthine guanine phosphoribosyl transferase YDR400W URH1 uridine ribohydrolase (EC 3.2.2.1) YDR408C ADE8 phosphoribosylglycinamide formyltransferase (GART) YDR410C STE14 farnesyl cysteine carboxyl-methyltransferase YDR420W HKR1 Hansenula MrakII k9 killer toxin-resistance protein YDR422C SIP1 multicopy suppressor of SNF1 YDR441C APT2 adenine phosphoribosyltransferase YDR443C SSN2 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDR444W YDR444W similarity to hypothetical protein YGL144c and YDL109c YDR452W PHM5 similarity to human sphingomyelin phosphodiesterase (PIR:S06957) YDR454C GUK1 guanylate kinase YDR465C RMT2 N-delta-arginine methyltransferase YDR477W SNF1 carbon catabolite derepressing ser/thr protein kinase YDR481C PHO8 repressible alkaline phosphatase vacuolar YDR483W KRE2 alpha-1,2-mannosyltransferase YDR487C RIB3 3,4-dihydroxy-2-butanone 4-phosphate synthase YDR497C ITR1 myo-inositol permease, major YDR502C SAM2 S-adenosylmethionine synthetase 2 YDR503C LPP1 lipid phosphate phosphatase YDR508C GNP1 high-affinity glutamine permease YDR513W TTR1 glutaredoxin YDR516C YDR516C strong similarity to glucokinase YDR530C APA2 ATP adenylyltransferase II YDR536W STL1 member of the sugar permease family YDR541C YDR541C similarity to dihydroflavonol-4-reductases YEL002C WBP1 oligosaccharyl transferase beta subunit precursor YEL004W YEA4 strong similarity to K.lactis golgi uridine diphosphate-N-acetylglucosamine transporter YEL009C GCN4 transcriptional activator of amino acid biosynthetic genes YEL011W GLC3 1,4-glucan branching enzyme (glycogen branching enzyme) YEL020C YEL020C similarity to O.formigenes oxalyl-CoA decarboxylase YEL021W URA3 orotidine-5'-phosphate decarboxylase YEL034W HYP2 translation initiation factor eIF5A.1 YEL038W UTR4 similarity to K.oxytoca enolase-phosphatase E-1 YEL046C GLY1 L-threonine aldolase, low-specific YEL058W PCM1 phosphoacetylglucosamine mutase YEL062W NPR2 nitrogen permease regulator YEL063C CAN1 amino acid permease YEL069C HXT13 high-affinity hexose transporter YEL070W YEL070W strong similarity to E.coli D-mannonate oxidoreductase YER001W MNN1 alpha-1,3-mannosyltransferase YER003C PMI40 mannose-6-phosphate isomerase YER014W HEM14 protoporphyrinogen oxidase, mitochondrial YER015W FAA2 long-chain-fatty-acid--CoA ligase YER019W ISC1 weak similarity to human and mouse neutral sphingomyelinase YER023W PRO3 delta 1-pyrroline-5-carboxylate reductase YER024W YAT2 carnitine O-acetyltransferase YER026C CHO1 CDP-diacylglycerol serine O-phosphatidyltransferase YER027C GAL83 glucose repression protein YER040W GLN3 transcription factor for positive nitrogen regulation YER042W MXR1 responsible for the reduction of methionine sulfoxide YER043C SAH1 S-adenosyl-L-homocysteine hydrolase YER044C ERG28 involved in synthesis of ergosterol YER052C HOM3 L-aspartate 4-P-transferase YER053C YER053C strong similarity to mitochondrial phosphate carrier protein YER054C GIP2 GLC7P-interacting protein YER055C HIS1 ATP phosphoribosyltransferase YER056C FCY2 purine-cytosine permease YER060W FCY21 purine-cytosine permease YER060W-A FCY22 purine/cytosine permease with similarity to FCY2P YER061C CEM1 beta-keto-acyl-ACP synthase, mitochondrial YER062C HOR2 DL-glycerol phosphatase YER065C ICL1 isocitrate lyase YER069W ARG5,6 acetylglutamate kinase and acetylglutamyl-phosphate reductase YER070W RNR1 ribonucleoside-diphosphate reductase, large subunit YER081W SER3 3-phosphoglycerate dehydrogenase YER086W ILV1 anabolic serine and threonine dehydratase precursor YER090W TRP2 anthranilate synthase component I YER091C MET6 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase YER096W SHC1 sporulation specific protein YER099C PRS2 ribose-phosphate pyrophosphokinase YER120W SCS2 required for inositol metabolism YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER170W ADK2 adenylate kinase, mitochondrial YER178W PDA1 pyruvate dehydrogenase (lipoamide) alpha chain precursor YER183C FAU1 similarity to human 5,10-methenyltetrahydrofolate synthetase YFL004W VTC2 putative polyphosphate synthetase YFL010W-A AUA1 involved in ammonia regulation of amino acid transport YFL011W HXT10 hexose transporter YFL014W HSP12 heat shock protein YFL018C LPD1 dihydrolipoamide dehydrogenase precursor YFL021W GAT1 transcription factor for nitrogen regulation YFL030W YFL030W similarity to several transaminases YFL031W HAC1 transcription factor YFL040W YFL040W similarity to yeast glucose transport proteins YFL045C SEC53 phosphomannomutase YFL052W YFL052W strong similarity to Mal63p, YPR196w and MAL13P YFL053W DAK2 dihydroxyacetone kinase YFL055W AGP3 amino acid permease YFL056C AAD6 strong similarity to aryl-alcohol dehydrogenases YFL057C YFL057C strong similarity to aryl-alcohol dehydrogenases YFL058W THI5 pyrimidine biosynthesis protein YFL061W YFL061W similarity to M.verrucaria cyanamide hydratase YFR015C GSY1 UDP glucose--starch glucosyltransferase, isoform 1 YFR018C YFR018C similarity to human glutaminyl-peptide cyclotransferase YFR019W FAB1 phosphatidylinositol 3-phosphate 5-kinase YFR025C HIS2 histidinol phosphatase YFR030W MET10 sulfite reductase flavin-binding subunit YFR034C PHO4 transcription factor YFR047C YFR047C strong similarity to human quinolinate phosphoribosyltransferase YFR053C HXK1 hexokinase I YFR055W YFR055W strong similarity to beta-cystathionases YGL001C ERG26 C-3 sterol dehydrogenase (C-4 decarboxylase) YGL009C LEU1 3-isopropylmalate dehydratase YGL012W ERG4 sterol C-24 reductase YGL017W ATE1 arginyl tRNA transferase YGL022W STT3 oligosaccharyl transferase subunit YGL026C TRP5 tryptophan synthase YGL027C CWH41 ER glucosidase I YGL035C MIG1 transcriptional repressor YGL038C OCH1 alpha-1,6-mannosyltransferase YGL039W YGL039W similarity to V. vinifera dihydroflavonol reductase YGL040C HEM2 porphobilinogen synthase YGL055W OLE1 stearoyl-CoA desaturase YGL062W PYC1 pyruvate carboxylase 1 YGL063W PUS2 pseudouridine synthase 2 YGL065C ALG2 mannosyltransferase YGL067W NPY1 NADH pyrophosphatase I of the Nudix family of hydrolases, has a peroxisomal targeting signal YGL104C YGL104C similarity to glucose transport proteins YGL115W SNF4 nuclear regulatory protein YGL125W MET13 putative methylene tetrahydrofolate reductase YGL126W SCS3 inositol phospholipid synthesis protein YGL134W PCL10 cyclin like protein interacting with PHO85P YGL142C GPI10 required for Glycosyl Phosphatdyl Inositol synthesis YGL144C YGL144C strong similarity to hypothetical protein YDL109c YGL148W ARO2 chorismate synthase YGL154C LYS5 L-aminoadipate-semialdehyde dehydrogenase, small subunit YGL155W CDC43 geranylgeranyltransferase beta subunit YGL156W AMS1 alpha-mannosidase YGL157W YGL157W similarity to V.vinifera dihydroflavonol 4-reductase YGL162W SUT1 hypoxic protein involved in sterol uptake YGL173C KEM1 multifunctional nuclease YGL184C STR3 strong similarity to Emericella nidulans and similarity to other cystathionine beta-lyase and CYS3P YGL186C YGL186C similarity to hypothetical protein FCY21P and weak similarity to FCY2 protein YGL202W ARO8 aromatic amino acid aminotransferase I YGL205W POX1 acyl-CoA oxidase YGL209W MIG2 C2H2 zinc-finger protein YGL226C-A OST5 subunit of N-oligosaccharyltransferase, zeta subunit YGL234W ADE5,7 phosphoribosylamine-glycine ligase and phosphoribosylformylglycinamidine cyclo-ligase YGL248W PDE1 low affinity 3',5'-cyclic-nucleotide phosphodiesterase YGL252C RTG2 retrograde regulation protein YGL253W HXK2 hexokinase II YGL254W FZF1 sulfite resistance protein YGL256W ADH4 alcohol dehydrogenase IV YGL257C MNT2 alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides YGR007W MUQ1 choline phosphate cytidylyltransferase YGR012W YGR012W similarity to E.nidulans cysteine synthase YGR019W UGA1 4-aminobutyrate aminotransferase (GABA transaminase) YGR032W GSC2 1,3-beta-D-glucan synthase subunit YGR037C ACB1 acyl-coenzyme-A-binding protein (diazepam binding inhibitor) YGR043C YGR043C strong similarity to transaldolase YGR055W MUP1 high affinity methionine permease YGR060W ERG25 C-4 sterol methyl oxidase YGR061C ADE6 5'-phosphoribosylformyl glycinamidine synthetase YGR070W ROM1 GDP/GTP exchange protein for RHO1P YGR072W UPF3 nonsense-mediated mRNA decay protein YGR087C PDC6 pyruvate decarboxylase 3 YGR096W YGR096W hypothetical mitochondrial transport protein YGR124W ASN2 asparagine synthetase YGR143W SKN1 glucan synthase subunit YGR144W THI4 involved in thiamine biosynthesis and DNA repair YGR155W CYS4 cystathionine beta-synthase YGR157W CHO2 phosphatidylethanolamine N-methyltransferase YGR166W KRE11 beta-glucan synthesis-associated protein YGR169C YGR169C similarity to RIB2P YGR170W PSD2 phosphatidylserine decarboxylase 2 YGR175C ERG1 squalene monooxygenase YGR177C ATF2 alcohol O-acetyltransferase YGR180C RNR4 ribonucleotide reductase small subunit YGR191W HIP1 histidine permease YGR192C TDH3 glyceraldehyde-3-phosphate dehydrogenase 3 YGR193C PDX1 pyruvate dehydrogenase complex protein X YGR194C XKS1 xylulokinase YGR195W SKI6 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YGR199W PMT6 putative mannosyltransferase YGR202C PCT1 cholinephosphate cytidylyltransferase YGR204W ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YGR208W SER2 phosphoserine phosphatase YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YGR227W DIE2 ITR1 expression promoting protein YGR229C SMI1 beta-1,3-glucan synthesis protein YGR233C PHO81 cyclin-dependent kinase inhibitor YGR240C PFK1 6-phosphofructokinase, alpha subunit YGR244C LSC2 succinate-CoA ligase beta subunit YGR254W ENO1 enolase I (2-phosphoglycerate dehydratase) YGR255C COQ6 monooxygenase YGR256W GND2 phosphogluconate dehydrogenase YGR267C FOL2 GTP cyclohydrolase I YGR276C RNH70 ribonuclease H YGR282C BGL2 endo-beta-1,3-glucanase of the cell wall YGR286C BIO2 biotin synthetase YGR287C YGR287C strong similarity to maltase YGR288W MAL13 maltose pathway regulatory protein YGR289C MAL11 general alpha-glucoside permease YGR292W MAL12 alpha-glucosidase of the MAL1 locus YHL003C LAG1 longevity-assurance protein YHL011C PRS3 ribose-phosphate pyrophosphokinase YHL012W YHL012W similarity to UDP Glucose pyrophosphorylase YHL018W YHL018W similarity to human pterin-4-alpha-carbinolamine dehydratase YHL020C OPI1 negative regulator of phospholipid biosynthesis pathway YHL025W SNF6 global transcription activator YHL032C GUT1 glycerol kinase YHL036W MUP3 very low affinity methionine permease YHR001W OSH7 similarity to KES1P YHR002W YHR002W similarity to bovine mitochondrial carrier protein/Grave's disease carrier protein YHR003C YHR003C strong similarity to molybdopterin-converting factor homolog YKL027w YHR007C ERG11 cytochrome P450 lanosterol 14a-demethylase YHR013C ARD1 protein N-acetyltransferase subunit YHR018C ARG4 arginosuccinate lyase YHR025W THR1 homoserine kinase YHR033W YHR033W strong similarity to glutamate 5-kinase YHR037W PUT2 1-pyrroline-5-carboxylate dehydrogenase YHR042W NCP1 NADPH-cytochrome P450 reductase YHR043C DOG2 2-deoxyglucose-6-phosphate phosphatase YHR044C DOG1 2-deoxyglucose-6-phosphate phosphatase YHR046C YHR046C similarity to inositolmonophosphatases YHR047C AAP1' alanine/arginine aminopeptidase YHR063C PAN5 weak similarity to translational activator CBS2 YHR068W DYS1 deoxyhypusine synthase YHR070W TRM5 strong similarity to N.crassa met-10+ protein YHR072W ERG7 lanosterol synthase YHR073W OSH3 similarity to OSH1P, YDL019c and mammalian oxysterol-binding protei YHR077C NMD2 nonsense-mediated mRNA decay protein 2 YHR079C IRE1 protein kinase YHR092C HXT4 moderate- to low-affinity glucose transporter YHR094C HXT1 low-affinity hexose transporter YHR096C HXT5 member of the hexose transporter family YHR101C BIG1 big cells phenotype YHR104W GRE3 aldose reductase YHR106W TRR2 thioredoxin reductase YHR107C CDC12 septin YHR111W YHR111W similarity to molybdopterin biosynthesis proteins YHR112C YHR112C similarity to cystathionine gamma-synthases YHR123W EPT1 sn-1,2-diacylglycerol ethanolamine- and cholinephosphotransferase YHR128W FUR1 uracil phosphoribosyltransferase YHR137W ARO9 aromatic amino acid aminotransferase II YHR144C DCD1 deoxycytidylate deaminase YHR155W YHR155W strong similarity to SNF1P-interacting protein SIP3P YHR174W ENO2 enolase II (2-phosphoglycerate dehydratase) YHR176W FMO flavin-containing monooxygenase YHR183W GND1 6-phosphogluconate dehydrogenase YHR190W ERG9 farnesyl-diphosphate farnesyltransferase YHR193C EGD2 alpha subunit of the nascent polypeptide-associated complex YHR201C PPX1 exopolyphosphatase YHR204W HTM1 similarity to alpha-mannosidases YHR208W BAT1 branched chain amino acid aminotransferase, mitochondrial YHR210C YHR210C strong similarity to UDP-glucose-4-epimerase YHR215W PHO12 secreted acid phosphatase YHR216W IMD2 IMP dehydrogenase YIL002C INP51 phosphatidylinositol phosphate 5-phosphatase YIL006W YIL006W similarity to FLX1P YIL009W FAA3 acyl CoA synthase YIL014W MNT3 alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides YIL020C HIS6 5' Pro-FAR isomerase YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL042C YIL042C similarity to rat branched-chain alpha-ketoacid dehydrogenase kinase YIL045W PIG2 Protein Interacting with GSY2P YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL053W RHR2 DL-glycerol phosphatase YIL066C RNR3 ribonucleotide reductase, repair inducible large subunit YIL074C SER33 3-phosphoglycerate dehydrogenase YIL078W THS1 threonyl tRNA synthetase, cytosolic YIL085C KTR7 putative alpha-1,2-mannosyltransferase YIL094C LYS12 homo-isocitrate dehydrogenase YIL098C FMC1 Formation of Mitochondrial Cytochromes YIL099W SGA1 sporulation specific glucan 1,4-alpha-glucosidase YIL107C PFK26 6-phosphofructose-2-kinase, isozyme 1 YIL116W HIS5 histidinol-phosphate aminotransferase YIL119C RPI1 negative regulator of ras-cAMP pathway YIL124W AYR1 1-Acyldihydroxyacetone-phosphate reductase YIL125W KGD1 2-oxoglutarate dehydrogenase complex E1 component YIL134W FLX1 FAD carrier protein (MCF), mitochondrial YIL145C PAN6 protein required for synthesis of pantothenic acid YIL147C SLN1 two-component signal transducer YIL154C (IMP2) sugar utilization regulatory protein YIL155C GUT2 glycerol-3-phosphate dehydrogenase, mitochondrial YIL160C POT1 acetyl-CoA C-acyltransferase, peroxisomal YIL162W SUC2 invertase (sucrose hydrolyzing enzyme) YIL167W SDL1 serine dehydratase YIL168W SDL1 serine dehydratase YIL170W HXT12 strong similarity to sugar transport proteins YIL171W HXT12 strong similarity to sugar transport proteins YIL172C YIL172C identical to FSP2P and similarity to other alpha-glucosidases YIR017C MET28 transcriptional activator of sulfur amino acid metabolism YIR019C MUC1 extracellular alpha-1,4-glucan glucosidase YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YIR027C DAL1 allantoinase YIR029W DAL2 allantoinase YIR030C DCG1 involved in nitrogen-catabolite metabolism YIR031C DAL7 malate synthase 2 YIR032C DAL3 ureidoglycolate hydrolase YIR034C LYS1 saccharopine dehydrogenase YIR035C YIR035C similarity to human corticosteroid 11-beta-dehydrogenase YIR036C YIR036C similarity to E.coli fabD YJL002C OST1 oligosaccharyltransferase, alpha subunit YJL005W CYR1 adenylate cyclase YJL026W RNR2 ribonucleoside-diphosphate reductase, small subunit YJL031C BET4 geranylgeranyl transferase, alpha chain YJL045W YJL045W strong similarity to succinate dehydrogenase flavoprotein YJL052W TDH1 glyceraldehyde-3-phosphate dehydrogenase 1 YJL060W YJL060W similarity to kynurenine aminotransferase and glutamine-phenylpyruvate transaminase YJL068C YJL068C strong similarity to human esterase D YJL070C YJL070C similarity to AMP deaminases YJL071W ARG2 acetylglutamate synthase YJL088W ARG3 ornithine carbamoyltransferase YJL099W CHS6 chitin biosynthesis protein YJL110C GZF3 transcriptional repressor YJL117W PHO86 inorganic phospate transporter YJL121C RPE1 D-ribulose-5-phosphate 3-epimerase YJL126W NIT2 nitrilase YJL128C PBS2 tyrosine protein kinase of the MAP kinase kinase family YJL130C URA2 multifunctional pyrimidine biosynthesis protein YJL132W YJL132W weak similarity to human phospholipase D YJL134W LCB3 sphingoid base-phosphate phosphatase YJL137C GLG2 self-glucosylating initiator of glycogen synthesis YJL139C YUR1 mannosyltransferase YJL145W YJL145W weak similarity to T.pacificus retinal-binding protein YJL153C INO1 myo-inositol-1-phosphate synthase YJL155C FBP26 fructose-2,6-bisphosphatase YJL167W ERG20 farnesyl-pyrophosphate synthetase YJL172W CPS1 Gly-X carboxypeptidase YSCS precursor YJL174W KRE9 cell wall synthesis protein YJL176C SWI3 transcription regulatory protein YJL186W MNN5 putative mannosyltransferase YJL196C ELO1 fatty acid elongation protein YJL198W PHO90 low affinity phosphate transporter YJL208C NUC1 nuclease, mitochondrial YJL214W HXT8 hexose transport protein YJL216C YJL216C strong similarity to Mal62p YJL218W YJL218W strong similarity to E.coli galactoside O-acetyltransferase YJL219W HXT9 hexose transport protein YJL221C FSP2 strong similarity to alpha-D-glucosidase YJR009C TDH2 glyceraldehyde-3-phosphate dehydrogenase 2 YJR010W MET3 sulfate adenylyltransferase YJR016C ILV3 dihydroxy-acid dehydratase YJR019C TES1 thioesterase, peroxisomal YJR025C BNA1 3-hydroxyanthranilic acid dioxygenase YJR057W CDC8 dTMP kinase YJR060W CBF1 kinetochore protein YJR066W TOR1 phosphatidylinositol 3-kinase YJR073C OPI3 methylene-fatty-acyl-phospholipid synthase YJR075W HOC1 suppressor of PKC1 YJR076C CDC11 septin YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YJR078W YJR078W similarity to mammalian indoleamine 2,3-dioxygenase YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR095W SFC1 succinate-fumarate transporter YJR096W YJR096W similarity to Corynebacterium 2,5-diketo-D-gluconic acid reductase and aldehyde reductases YJR103W URA8 CTP synthase 2 YJR105W ADO1 strong similarity to human adenosine kinase YJR107W YJR107W weak similarity to acylglycerol lipase YJR109C CPA2 arginine-specific carbamoylphosphate synthase, large chain YJR130C STR2 similarity to O-succinylhomoserine (thiol)-lyase YJR131W MNS1 alpha1,2-mannosidase YJR132W NMD5 NAM7P interacting protein YJR133W XPT1 xanthine phosphoribosyl transferase YJR137C ECM17 involved in cell wall biogenesis and architecture YJR139C HOM6 homoserine dehydrogenase YJR142W YJR142W similarity to thiamin pyrophosphokinase YJR143C PMT4 dolichyl-phosphate-mannose--protein O-mannosyl transferase YJR148W BAT2 branched chain amino acid aminotransferase, cytosolic YJR149W YJR149W similarity to 2-nitropropane dioxygenase YJR153W PGU1 Endo-polygalacturonase YJR155W AAD10 strong similarity to aryl-alcohol dehydrogenase YJR156C THI11 thiamine regulated gene, homologous to nmt1a in S. pombe YJR158W HXT16 member of the hexose transporter family of the major facilitator superfamily [MFS] YJR159W SOR1 sorbitol dehydrogenase YJR160C YJR160C strong similarity to MAL31P YKL001C MET14 ATP adenosine-5'-phosphosulfate 3'-phosphotransferase YKL004W AUR1 aureobasidin-resistance protein YKL009W MRT4 mRNA turnover 4 YKL015W PUT3 positive activator of the proline utilisation pathway YKL019W RAM2 protein farnesyltransferase, alpha subunit YKL024C URA6 uridine-monophosphate kinase YKL027W YKL027W similarity to E.coli molybdopterin-converting factor chlN YKL029C MAE1 malic enzyme YKL035W UGP1 UTP--glucose-1-phosphate uridylyltransferase YKL038W RGT1 regulator of glucose-induced genes YKL040C NFU1 iron homeostasis YKL055C OAR1 putative 3-oxoacyl-(acyl carrier protein) reductase YKL060C FBA1 fructose-bisphosphate aldolase YKL062W MSN4 transcriptional activator YKL067W YNK1 nucleoside diphosphate kinase YKL085W MDH1 malate dehydrogenase precursor, mitochondrial YKL087C CYT2 holocytochrome-c1 synthase YKL104C GFA1 glucosamine--fructose-6-phosphate transaminase YKL106W AAT1 aspartate transaminase, mitochondrial YKL112W ABF1 ARS-binding factor YKL124W SSH4 suppressor of SHR3 YKL127W PGM1 phosphoglucomutase, minor isoform YKL132C RMA1 similarity to B.subtilis folC protein and strong similarity to YMR113w YKL140W TGL1 triacylglycerol lipase YKL148C SDH1 succinate dehydrogenase flavoprotein precursor YKL149C DBR1 lariat-debranching enzyme YKL152C GPM1 phosphoglycerate mutase YKL157W APE2 aminopeptidase yscII YKL174C YKL174C similarity to choline transport protein HNM1P YKL181W PRS1 ribose-phosphate pyrophosphokinase YKL182W FAS1 fatty-acyl-CoA synthase, beta chain YKL184W SPE1 ornithine decarboxylase YKL188C PXA2 ABC transporter, peroxisomal YKL191W DPH2 diphtheria toxin resistance protein YKL192C ACP1 mitochonrial acyl-carrier protein YKL203C TOR2 phosphatidylinositol 3-kinase YKL211C TRP3 anthranilate synthase component II YKL213C DOA1 involved in ubiquitin-dependent proteolysis YKL215C YKL215C similarity to P. aeruginosa hyuA and hyuB YKL216W URA1 dihydroorotate dehydrogenase YKL217W JEN1 carboxylic acid transporter protein YKL218C SRY1 strong similarity to E.coli and H.influenzae threonine dehydratases YKR003W OSH6 similarity to KES1P, HES1P and OSH1P YKR009C FOX2 hydratase-dehydrogenase-epimerase, peroxisomal YKR027W YKR027W strong similarity to CHS6P YKR031C SPO14 phospholipase D YKR034W DAL80 transcriptional repressor for allantoin and GABA catabolic genes YKR039W GAP1 general amino acid permease YKR043C YKR043C weak similarity to phosphoglycerate mutase YKR053C YSR3 dihydrosphingosine-1-phosphate phosphatase YKR061W KTR2 mannosyltransferase YKR069W MET1 siroheme synthase YKR080W MTD1 methylenetetrahydrofolate dehydrogenase (NAD+) YKR096W YKR096W similarity to mitochondrial aldehyde dehydrogenase Ald1p YKR097W PCK1 phosphoenolpyruvate carboxykinase YKR099W BAS1 transcription factor YLL012W YLL012W similarity to triacylglycerol lipases YLL013C PUF3 transcript-specific regulator of mRNA degradation YLL016W SDC25 GDP/GTP exchange factor (GEF) YLL031C GPI13 protein involved in glycosylphosphatidylinositol biosynthesis YLL043W FPS1 glycerol channel protein YLL048C YBT1 yeast bile transporter YLL058W YLL058W similarity to N.crassa O-succinylhomoserine (thiol)-lyase YLL061W MMP1 high affinity S-methylmethionine permease YLR006C SSK1 two-component signal transducer YLR013W GAT3 weak similarity to nitrogen regulatory proteins YLR014C PPR1 transcription factor regulating pyrimidine pathway YLR017W MEU1 multiple enhancer of UAS2 YLR020C YLR020C similarity to triacylglycerol lipase YLR025W SNF7 class E Vps protein YLR027C AAT2 aspartate aminotransferase, cytosolic YLR028C ADE16 5-aminoimidazole-4-carboxamide ribotide transformylase YLR044C PDC1 pyruvate decarboxylase, isozyme 1 YLR056W ERG3 C-5 sterol desaturase YLR058C SHM2 serine hydroxymethyltransferase, cytoplasmic YLR070C YLR070C strong similarity to sugar dehydrogenases YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR081W GAL2 galactose (and glucose) permease YLR088W GAA1 required for attachment of GPI anchor onto proteins YLR089C YLR089C strong similarity to alanine transaminases YLR092W SUL2 sulfate transporter YLR098C CHA4 transcription factor YLR099C ICT1 similarity to YDR125c YLR100W ERG27 3-keto sterol reductase YLR107W REX3 RNA exonuclease, member of the family of 3' -5' exonucleases YLR113W HOG1 ser/thr protein kinase of MAP kinase (MAPK) family YLR131C ACE2 metallothionein expression activator YLR133W CKI1 choline kinase YLR134W PDC5 pyruvate decarboxylase, isozyme 2 YLR142W PUT1 proline oxidase YLR146C SPE4 spermine synthase YLR150W STM1 specific affinity for guanine-rich quadruplex nucleic acids YLR151C PCD1 peroxisomal nudix hydrolase, has diphosphatase activity specific for coenzyme A and CoA derivatives YLR153C ACS2 acetyl-coenzyme A synthetase YLR155C ASP3A L-asparaginase II YLR157C ASP3B L-asparaginase II YLR158C ASP3C L-asparaginase II YLR160C ASP3D L-asparaginase II YLR164W YLR164W strong similarity to SDH4P YLR165C PUS5 RNA:pseudouridine (Psi)-synthase YLR172C DPH5 diphthamide methyltransferase YLR174W IDP2 isocitrate dehydrogenase, cytosolic YLR180W SAM1 S-adenosylmethionine synthetase 1 YLR189C UGT51 sterol glucosyltransferase (UDP-glucose:sterol glucosyltransferase) YLR195C NMT1 N-myristoyltransferase YLR205C HMX1 weak similarity to heme oxygenase 'Rhodella violacea HO_RHOVL' YLR209C PNP1 strong similarity to purine-nucleoside phosphorylases YLR231C YLR231C strong similarity to rat kynureninase YLR237W THI7 thiamin transport protein YLR239C LIP2 lipoic acid ligase YLR240W VPS34 phosphatidylinositol 3-kinase YLR245C CDD1 cytidine deaminase YLR258W GSY2 UDP-glucose--starch glucosyltransferase, isoform 2 YLR260W LCB5 sphingolipid long chain base kinase YLR273C PIG1 putative type 1 phosphatase regulatory subunit YLR284C ECI1 delta3-cis-delta2-trans-enoyl-CoA isomerase YLR286C CTS1 endochitinase YLR299W ECM38 gamma-glutamyltransferase, involved in glutathione synthesis YLR300W EXG1 exo-beta-1,3-glucanase (I/II), major isoform YLR303W MET17 O-acetylhomoserine sulfhydrylase YLR304C ACO1 aconitate hydratase YLR305C STT4 phosphatidylinositol-4-kinase YLR307W CDA1 sporulation-specific chitin deacetylase YLR308W CDA2 sporulation-specific chitin deacetylase YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR330W CHS5 chitin synthesis protein YLR342W FKS1 1,3-beta-D-glucan synthase, catalytic subunit YLR345W YLR345W similarity to PFK26P and other 6-phosphofructo-2-kinases YLR348C DIC1 dicarboxylate carrier protein YLR351C NIT3 nitrilase YLR354C TAL1 transaldolase YLR355C ILV5 ketol-acid reducto-isomerase YLR359W ADE13 adenylosuccinate lyase YLR363C NMD4 NAM7P interacting protein YLR371W ROM2 GDP/GTP exchange factor for RHO1P YLR372W SUR4 sterol isomerase, fatty acid elongase YLR375W STP3 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YLR377C FBP1 fructose-1,6-bisphosphatase YLR380W CSR1 phosphatidylinositol transfer protein YLR420W URA4 dihydroorotase YLR432W IMD3 strong similarity to IMP dehydrogenases, Pur5p and YML056c YLR438W CAR2 ornithine aminotransferase YLR450W HMG2 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 YLR451W LEU3 transcription factor YML004C GLO1 glyoxalase I YML008C ERG6 S-adenosyl-methionine delta-24-sterol-c-methyltransferase YML019W OST6 N-oligosaccharyltransferase complex subunit YML022W APT1 adenine phosphoribosyltransferase YML035C AMD1 AMP deaminase YML042W CAT2 carnitine O-acetyltransferase YML048W GSF2 involved in glucose repression YML051W GAL80 negative regulator for expression of galactose-induced genes YML054C CYB2 lactate dehydrogenase cytochrome b2 YML056C IMD4 strong similarity to IMP dehydrogenases YML058W SML1 protein inhibitor of ribonucleotide reductase YML070W DAK1 dihydroxyacetone kinase, induced in high salt YML075C HMG1 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 YML082W YML082W similarity to N.crassa O-succinylhomoserine (thiol)-lyase YML086C ALO1 D-arabinono-1,4-lactone oxidase YML096W YML096W similarity to asparagine synthases YML099C ARG81 transcription factor involved in arginine metabolism YML100W TSL1 alpha,alpha-trehalose-phosphate synthase, 123 KD subunit YML106W URA5 orotate phosphoribosyltransferase YML110C COQ5 ubiquinone biosynthesis, methyltransferase YML121W GTR1 GTP-binding protein YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YML126C ERG13 3-hydroxy-3-methylglutaryl coenzyme A synthase YML131W YML131W similarity to human leukotriene b4 12-hydroxydehydrogenase YMR006C PLB2 strong similarity to PLB1P, YOL011w and P.notatum lysophospholipase YMR008C PLB1 phospholipase B (lysophospholipase) YMR011W HXT2 high-affinity hexose transporter YMR013C SEC59 dolichol kinase YMR015C ERG5 C-22 sterol desaturase YMR020W FMS1 involved in the biosynthesis of pantothenic acid YMR042W ARG80 transcription factor involved in arginine metabolism YMR043W MCM1 transcription factor of the MADS box family YMR056C AAC1 ADP/ATP carrier protein (MCF) YMR060C TOM37 mitochondrial outer membrane import receptor subunit, 37 kD YMR062C ECM40 acetylornithine acetyltransferase YMR079W SEC14 phosphatidylinositol(PI)/phosphatidylcholine(PC) transfer protein YMR080C NAM7 nonsense-mediated mRNA decay protein YMR081C ISF1 involved in suppression of mitochondrial splicing defect YMR083W ADH3 alcohol dehydrogenase III YMR105C PGM2 phosphoglucomutase, major isoform YMR108W ILV2 acetolactate synthase YMR113W FOL3 dihydrofolate synthetase YMR120C ADE17 5-aminoimidazole-4-carboxamide ribotide transformylase YMR149W SWP1 oligosaccharyltransferase delta subunit YMR189W GCV2 glycine decarboxylase P subunit YMR202W ERG2 C-8 sterol isomerase YMR205C PFK2 6-phosphofructokinase, beta subunit YMR207C HFA1 strong similarity to acetyl-CoA carboxylase YMR208W ERG12 mevalonate kinase YMR217W GUA1 GMP synthase (glutamine-hydrolyzing) YMR220W ERG8 phosphomevalonate kinase YMR222C YMR222C similarity to S.pombe dihydrofolate reductase YMR234W RNH1 ribonuclease H YMR237W YMR237W similarity to CHS6 protein YMR246W FAA4 long-chain-fatty-acid--CoA ligase YMR250W GAD1 similarity to glutamate decarboxylases YMR261C TPS3 alpha,alpha-trehalose-phosphate synthase, 115 KD subunit YMR267W PPA2 inorganic pyrophosphatase, mitochondrial YMR271C URA10 orotate phosphoribosyltransferase2 YMR272C SCS7 required for hydroxylation of ceramide YMR278W YMR278W similarity to phosphomannomutases YMR280C CAT8 transcription factor involved in gluconeogenesis YMR281W GPI12 N-acetylglucosaminyl phosphatidylinositol deacetylase YMR282C AEP2 required for the expression of subunit-9 of atp synthase YMR287C MSU1 3'-5' exonuclease for RNA 3' ss-tail, mitochondrial YMR293C YMR293C similarity to amidases YMR296C LCB1 serine C-palmitoyltransferase subunit YMR300C ADE4 amidophosphoribosyltransferase YMR303C ADH2 alcohol dehydrogenase II YMR306W FKS3 similarity to 1,3-beta-glucan synthases YMR307W GAS1 glycophospholipid-anchored surface glycoprotein YMR311C GLC8 regulatory subunit for protein ser/thr phosphatase GLC7P YMR318C YMR318C strong similarity to alcohol-dehydrogenase YMR323W YMR323W strong similarity to phosphopyruvate hydratases YNL009W IDP3 isocitrate dehydrogenase, NADP-dependent YNL012W SPO1 transcriptional regulator involved in sporulation YNL025C SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YNL029C KTR5 putative mannosyltransferase YNL037C IDH1 isocitrate dehydrogenase (NAD+) subunit 1, mitochondrial YNL040W YNL040W weak similarity to M.genitalium alanine--tRNA ligase YNL045W YNL045W strong similarity to human leukotriene-A4 hydrolase YNL048W ALG11 required for asparagine-linked glycosylation YNL066W SUN4 strong similarity to YIL123w, UTH1P, NCA3P and C. wickerhamii beta-glucosidase protein YNL071W LAT1 dihydrolipoamide S-acetyltransferase YNL072W RNH35 RNase H(35), a 35 kDa ribonuclease H YNL076W MKS1 pleiotropic regulatory factor YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL098C RAS2 GTP-binding protein YNL103W MET4 transcriptional activator of sulfur metabolism YNL104C LEU4 2-isopropylmalalate synthase YNL106C INP52 phosphatidylinositol phosphate phosphatase YNL111C CYB5 cytochrome b5 YNL117W MLS1 malate synthase 1 YNL130C CPT1 diacylglycerol cholinephosphotransferase YNL141W AAH1 adenosine deaminase YNL169C PSD1 phosphatidylserine decarboxylase 1 YNL183C NPR1 ser/thr protein kinase YNL192W CHS1 chitin synthase I YNL199C GCR2 glycolytic genes transcriptional activator YNL201C YNL201C weak similarity to pleiotropic drug resistance control protein PDR6 YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL219C ALG9 mannosyltransferase YNL220W ADE12 adenylosuccinate synthetase YNL229C URE2 nitrogen catabolite repression regulator YNL231C PDR16 protein involved in lipid biosynthesis and multidrug resistance YNL232W CSL4 core component of the 3'-5' exosome YNL236W SIN4 global regulator protein YNL241C ZWF1 glucose-6-phosphate dehydrogenase YNL243W SLA2 cytoskeleton assembly control protein YNL256W FOL1 Dihydroneopterin aldolase, dihydro-6-hydroxymethylpterin pyrophosphokinase, dihydropteroate synthetase YNL257C SIP3 SNF1P protein kinase interacting protein YNL264C PDR17 involved in regulating phosphatidylserine metabolism YNL267W PIK1 phosphatidylinositol 4-kinase YNL268W LYP1 lysine-specific high-affinity permease YNL270C ALP1 high-affinity permease for basic amino acids YNL274C YNL274C similarity to glycerate- and formate-dehydrogenases YNL277W MET2 homoserine O-acetyltransferase YNL280C ERG24 C-14 sterol reductase YNL283C WSC2 glucoamylase III (alpha-1,4-glucan-glucosidase) YNL292W PUS4 pseudouridine synthase YNL314W DAL82 transcriptional activator for allantoin catabolic genes YNL316C PHA2 prephenate dehydratase YNL318C HXT14 hexose transport protein YNL322C KRE1 cell wall protein YNL330C RPD3 histone deacetylase B YNL331C AAD14 strong similarity aryl-alcohol reductase YNL332W THI12 nearly identical to THI5P, THI11 and YDL244w YNL333W SNZ2 putative pyridoxine (vitamin B6) biosynthetic enzyme YNL335W YNL335W similarity to M.verrucaria cyanamide hydratase, identical to hypothetical protein YFL061w YNR001C CIT1 citrate (si)-synthase, mitochondrial YNR002C FUN34 strong similarity to Y.lipolytica glyoxylate pathway regulator GPR1 YNR008W LRO1 a lecithin cholesterol acyltransferase-like gene, mediates diacylglycerol esterification YNR012W URK1 uridine kinase YNR013C PHO91 similarity to PHO87P and PHO90P YNR016C ACC1 acetyl-CoA carboxylase YNR019W ARE2 acyl-CoA sterol acyltransferase YNR027W BUD17 similarity to human pyridoxal kinase YNR033W ABZ1 para-aminobenzoate synthase YNR041C COQ2 para-hydroxybenzoate--polyprenyltransferase YNR043W MVD1 mevalonate pyrophosphate decarboxylase YNR050C LYS9 saccharopine dehydrogenase (NADP+, L-glutamate forming) YNR052C POP2 required for glucose derepression YNR056C BIO5 similarity to choline transport protein HNM1P YNR057C BIO4 putative dethiobiotin synthetase YNR058W BIO3 DAPA aminotransferase YNR059W MNT4 similarity to to alpha-1,3-mannosyltransferase YNR071C YNR071C strong similarity to UDP-glucose 4-epimerase GAL10P YNR072W HXT17 sugar transport protein YNR073C YNR073C strong similarity to E.coli D-mannonate oxidoreductase, identical to YEL070w YOL001W PHO80 cyclin YOL004W SIN3 transcription regulatory protein YOL007C CSI2 involved in chitin synthesis YOL011W PLB3 phospholipase B (lysophospholipase) YOL020W TAT2 high affinity tryptophan transport protein YOL049W GSH2 Glutathione synthetase YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL052C SPE2 adenosylmethionine decarboxylase precursor YOL056W GPM3 phosphoglycerate mutase YOL058W ARG1 argininosuccinate synthetase YOL059W GPD2 glycerol-3-phosphate dehydrogenase (NAD+), mitochondrial YOL061W PRS5 ribose-phosphate pyrophosphokinases YOL064C MET22 protein ser/thr phosphatase YOL065C INP54 inositol polyphosphate 5-phosphatase YOL066C RIB2 DRAP deaminase YOL067C RTG1 basic helix-loop-helix transcription factor that regulates CIT2 gene expression YOL081W IRA2 GTPase-activating protein for RAS proteins YOL086C ADH1 alcohol dehydrogenase I YOL096C COQ3 enzyme of ubiquinone (coenzyme Q) biosynthesis YOL103W ITR2 myo-inositol permease, minor YOL108C INO4 basic helix-loop-helix transcription factor YOL110W SHR5 RAS suppressor YOL116W MSN1 transcriptional activator YOL126C MDH2 malate dehydrogenase, cytoplasmic YOL136C PFK27 6-phosphofructose-2-kinase, isoenzyme 2 YOL140W ARG8 acetylornithine aminotransferase YOL143C RIB4 6,7-dimethyl-8-ribityllumazine synthase YOL151W GRE2 similarity to plant dihydroflavonol-4-reductases YOL153C YOL153C strong similarity to CPS1P YOL156W HXT11 low affinity glucose transport protein YOL157C YOL157C strong similarity to alpha-glucosidases YOL165C AAD15 putative aryl alcohol dehydrogenase YOR002W ALG6 glucosyltransferase YOR033C EXO1 exonuclease which interacts with MSH2P YOR040W GLO4 glyoxalase II (hydroxyacylglutathione hydrolase) YOR047C STD1 dosage-dependent modulator of glucose repression YOR067C ALG8 glucosyltransferase YOR071C YOR071C strong similarity to Thi10p YOR074C CDC21 thymidylate synthase YOR076C SKI7 GTPase with function in 3'-to-5' degradation of mRNA YOR085W OST3 oligosaccharyltransferase gamma subunit YOR095C RKI1 D-ribose-5-phosphate ketol-isomerase YOR099W KTR1 mannosyltransferase involved in n-linked and o-linked glycosylation YOR101W RAS1 GTP-binding protein YOR103C OST2 oligosaccharyltransferase epsilon subunit YOR108W YOR108W strong similarity to LEU4P YOR109W INP53 phosphatidylinositol phosphate phosphatase YOR110W TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa YOR120W GCY1 galactose-induced protein of aldo/keto reductase family YOR125C CAT5 involved in coenzyme Q (ubiquinone) biosynthesis YOR126C IAH1 isoamyl acetate hydrolytic enzyme YOR128C ADE2 phosphoribosylaminoimidazole carboxylase YOR130C ORT1 ornithine transport protein of mitochondria involved in arginine metabolism, member of the mitochondrial carrier family (MCF) YOR136W IDH2 isocitrate dehydrogenase (NAD+) subunit 2, mitochondrial YOR142W LSC1 succinate-CoA ligase alpha subunit YOR143C THI80 thiamin pyrophosphokinase YOR153W PDR5 pleiotropic drug resistance protein YOR171C LCB4 sphingolipid long chain base kinase YOR176W HEM15 ferrochelatase precursor YOR178C GAC1 ser/thr phosphoprotein phosphatase 1, regulatory chain YOR180C DCI1 Enoyl-CoA Hydratase, peroxisomal YOR184W SER1 phosphoserine transaminase YOR190W SPR1 exo-1,3-beta-glucanase precursor YOR192C YOR192C strong similarity to Thi10p YOR196C LIP5 lipoic acid synthase YOR202W HIS3 imidazoleglycerol-phosphate dehydratase YOR209C NPT1 nicotinate phosphoribosyltransferase YOR221C MCT1 malonyl-CoA:ACP transferase YOR222W ODC2 similarity to ADP/ATP carrier proteins YOR226C ISU2 strong similarity to nitrogen fixation proteins YOR236W DFR1 dihydrofolate reductase YOR237W HES1 involved in ergosterol biosynthesis YOR241W MET7 tetrahydrofolylpolyglutamate synthase YOR251C YOR251C similarity to thiosulfate sulfurtransferases YOR278W HEM4 uroporphyrinogen III synthase YOR280C YOR280C similarity to S.pombe dihydrofolate reductase YOR283W YOR283W weak similarity to phosphoglycerate mutases YOR290C SNF2 component of SWI/SNF global transcription activator complex YOR299W BUD7 involved in bud-site selection YOR303W CPA1 arginine-specific carbamoylphosphate synthase, small chain YOR317W FAA1 long-chain-fatty-acid--CoA ligase YOR321W PMT3 mannosyltransferase YOR323C PRO2 gamma-glutamyl phosphate reductase YOR336W KRE5 killer toxin-resistance protein YOR344C TYE7 basic helix-loop-helix transcription factor YOR347C PYK2 pyruvate kinase, glucose-repressed isoform YOR348C PUT4 proline and gamma-aminobutyrate permease YOR360C PDE2 high affinity 3',5'-cyclic-nucleotide phosphodiesterase YOR363C PIP2 peroxisome proliferating transcription factor YOR370C MRS6 geranylgeranyltransferase regulatory subunit YOR375C GDH1 glutamate dehydrogenase (NADP+) YOR377W ATF1 alcohol acetyltransferase YOR393W ERR1 enolase related protein YPL002C SNF8 involved in glucose derepression YPL006W NCR1 similarity to human PTC protein involved in nevoid basal cell carcinoma syndrome YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL017C YPL017C strong similarity to LPD1P and other dihydrolipoamide dehydrogenases YPL023C MET12 methylenetetrahydrofolate reductase YPL026C SKS1 suppressor kinase of SNF3 YPL028W ERG10 acetyl-CoA C-acetyltransferase, cytosolic YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL031C PHO85 cyclin-dependent protein kinase YPL037C EGD1 GAL4 DNA-binding enhancer protein YPL038W MET31 transcriptional regulator of sulfur amino acid metabolism YPL042C SSN3 cyclin-dependent CTD kinase YPL050C MNN9 required for complex N-glycosylation YPL053C KTR6 mannosylphosphate transferase YPL057C SUR1 required for mannosylation of sphingolipids YPL069C BTS1 geranylgeranyl diphosphate synthase YPL075W GCR1 transcriptional activator YPL076W GPI2 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein YPL087W YDC1 alkaline dihydroceramidase YPL088W YPL088W similarity to aryl-alcohol dehydrogenases YPL111W CAR1 arginase YPL113C YPL113C similarity to glycerate dehydrogenases YPL117C IDI1 isopentenyl-diphosphate delta-isomerase YPL123C RNY1 similarity to ribonucleases YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL132W COX11 cytochrome-c oxidase assembly protein YPL135W ISU1 strong similarity to nitrogen fixation protein (nifU) YPL145C KES1 involved in ergosterol biosynthesis YPL147W PXA1 long-chain fatty acid transporter YPL148C PPT2 phosphopantetheine protein transferase YPL161C BEM4 bud emergence protein YPL172C COX10 farnesyl transferase YPL175W SPT14 N-acetylglucosaminyltransferase YPL212C PUS1 pseudouridine synthase 1 YPL214C THI6 thiamin-phosphate pyrophosphorylase and hydroxyethylthiazole kinase YPL219W PCL8 cyclin like protein interacting with PHO85P YPL227C ALG5 dolichol-P-glucose synthetase YPL231W FAS2 fatty-acyl-CoA synthase, alpha chain YPL248C GAL4 transcription factor YPL265W DIP5 dicarboxylic amino acid permease YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YPL274W SAM3 high affinity S-adenosylmethionine permease YPL281C ERR2 enolase related protein YPR001W CIT3 citrate (si)-synthase, mitochondrial YPR006C ICL2 non-functional isocitrate lyase YPR011C YPR011C similarity to ADP/ATP carrier proteins and Graves disease carrier protein YPR021C YPR021C similarity to human citrate transporter protein YPR026W ATH1 acid trehalase, vacuolar YPR035W GLN1 glutamate--ammonia ligase YPR048W TAH18 similarity to M.domestica NADPH--ferrihemoprotein reductase and mammalian nitric-oxide synthases YPR060C ARO7 chorismate mutase YPR062W FCY1 cytosine deaminase YPR065W ROX1 heme-dependent transcriptional repressor of hypoxic genes YPR069C SPE3 putrescine aminopropyltransferase (spermidine synthase) YPR074C TKL1 transketolase 1 YPR113W PIS1 CDP diacylglycerol--inositol 3-phosphatidyltransferase YPR145W ASN1 asparagine synthetase YPR159W KRE6 glucan synthase subunit YPR160W GPH1 glycogen phosphorylase YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins YPR167C MET16 3'-phosphoadenylylsulfate reductase YPR176C BET2 geranylgeranyltransferase type II beta subunit YPR183W DPM1 dolichyl-phosphate beta-D-mannosyltransferase YPR184W GDB1 similarity to human 4-alpha-glucanotransferase (EC 2.4.1.25)/amylo-1,6-glucosidase (EC 3.2.1.33) Q0055 AI2 COX1 intron 2 protein Q0060 AI3 DNA endonuclease amino acid metabolism (204 ORFs) 01.01 204 YAL004W YAL004W strong similarity to A.klebsiana glutamate dehydrogenase YAL012W CYS3 cystathionine gamma-lyase YAL021C CCR4 transcriptional regulator YAL044C GCV3 glycine decarboxylase, subunit H YAL062W GDH3 NADP-glutamate dehydrogenase YBL098W YBL098W similarity to human and D.melanogaster kynurenine 3-monooxygenase YBR006W UGA2 succinate semialdehyde dehydrogenase YBR068C BAP2 leucine permease, high-affinity (S1) YBR069C TAT1 amino acid permease YBR084W MIS1 C1-tetrahydrofolate synthase precursor, mitochondrial YBR115C LYS2 L-aminoadipate-semialdehyde dehydrogenase, large subunit YBR117C TKL2 transketolase 2 YBR132C AGP2 amino-acid permease YBR166C TYR1 prephenate dehydrogenase (NADP+) YBR208C DUR1,2 urea amidolyase YBR213W MET8 siroheme synthase YBR248C HIS7 glutamine amidotransferase/cyclase YBR249C ARO4 2-dehydro-3-deoxyphosphoheptonate aldolase, tyrosine-inhibited YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR294W SUL1 high-affinity sulfate transport protein YCL009C ILV6 acetolactate synthase, regulatory subunit YCL018W LEU2 beta-isopropyl-malate dehydrogenase YCL025C AGP1 asparagine and glutamine permease YCL030C HIS4 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase/histidinol dehydrogenase YCL064C CHA1 L-serine/L-threonine deaminase YCR028C FEN2 high affinity H+/pantothenate symporter YCR053W THR4 threonine synthase (o-p-homoserine p-lyase) YDL048C STP4 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YDL080C THI3 positive regulation factor of thiamin metabolism YDL131W LYS21 homocitrate synthase YDL132W CDC53 controls G1/S transition YDL171C GLT1 glutamate synthase (NAPDPH) (GOGAT) YDL182W LYS20 homocitrate synthase YDL215C GDH2 NAD-specific glutamate dehydrogenase (NAD) YDR007W TRP1 phosphoribosylanthranilate isomerase YDR019C GCV1 glycine decarboxylase, subunit T YDR034C LYS14 transcriptional activator of lysine pathway genes YDR035W ARO3 2-dehydro-3-deoxyphosphoheptonate aldolase, phenylalanine-inhibited YDR046C BAP3 valine transporter YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR111C YDR111C strong similarity to alanine transaminase YDR127W ARO1 arom pentafunctional enzyme YDR158W HOM2 aspartate-semialdehyde dehydrogenase YDR159W SAC3 leucine permease transcriptional regulator YDR160W SSY1 transcriptional regulator of several transporter genes YDR173C ARG82 arginine metabolism transcription factor YDR207C UME6 negative transcriptional regulator YDR234W LYS4 homoaconitase YDR253C MET32 transcriptional regulator of sulfur amino acid metabolism YDR272W GLO2 glyoxalase II (hydroxyacylglutathione hydrolase) YDR300C PRO1 glutamate 5-kinase YDR321W ASP1 asparaginase YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR354W TRP4 anthranilate phosphoribosyltransferase YDR465C RMT2 N-delta-arginine methyltransferase YDR502C SAM2 S-adenosylmethionine synthetase 2 YDR508C GNP1 high-affinity glutamine permease YEL009C GCN4 transcriptional activator of amino acid biosynthetic genes YEL038W UTR4 similarity to K.oxytoca enolase-phosphatase E-1 YEL046C GLY1 L-threonine aldolase, low-specific YEL063C CAN1 amino acid permease YER023W PRO3 delta 1-pyrroline-5-carboxylate reductase YER042W MXR1 responsible for the reduction of methionine sulfoxide YER052C HOM3 L-aspartate 4-P-transferase YER055C HIS1 ATP phosphoribosyltransferase YER069W ARG5,6 acetylglutamate kinase and acetylglutamyl-phosphate reductase YER081W SER3 3-phosphoglycerate dehydrogenase YER086W ILV1 anabolic serine and threonine dehydratase precursor YER090W TRP2 anthranilate synthase component I YER091C MET6 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase YFL010W-A AUA1 involved in ammonia regulation of amino acid transport YFL018C LPD1 dihydrolipoamide dehydrogenase precursor YFL030W YFL030W similarity to several transaminases YFL055W AGP3 amino acid permease YFR018C YFR018C similarity to human glutaminyl-peptide cyclotransferase YFR025C HIS2 histidinol phosphatase YFR030W MET10 sulfite reductase flavin-binding subunit YFR055W YFR055W strong similarity to beta-cystathionases YGL009C LEU1 3-isopropylmalate dehydratase YGL017W ATE1 arginyl tRNA transferase YGL026C TRP5 tryptophan synthase YGL125W MET13 putative methylene tetrahydrofolate reductase YGL148W ARO2 chorismate synthase YGL154C LYS5 L-aminoadipate-semialdehyde dehydrogenase, small subunit YGL184C STR3 strong similarity to Emericella nidulans and similarity to other cystathionine beta-lyase and CYS3P YGL202W ARO8 aromatic amino acid aminotransferase I YGR012W YGR012W similarity to E.nidulans cysteine synthase YGR019W UGA1 4-aminobutyrate aminotransferase (GABA transaminase) YGR055W MUP1 high affinity methionine permease YGR124W ASN2 asparagine synthetase YGR155W CYS4 cystathionine beta-synthase YGR191W HIP1 histidine permease YGR204W ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YGR208W SER2 phosphoserine phosphatase YHL011C PRS3 ribose-phosphate pyrophosphokinase YHL036W MUP3 very low affinity methionine permease YHR018C ARG4 arginosuccinate lyase YHR025W THR1 homoserine kinase YHR033W YHR033W strong similarity to glutamate 5-kinase YHR037W PUT2 1-pyrroline-5-carboxylate dehydrogenase YHR068W DYS1 deoxyhypusine synthase YHR070W TRM5 strong similarity to N.crassa met-10+ protein YHR112C YHR112C similarity to cystathionine gamma-synthases YHR137W ARO9 aromatic amino acid aminotransferase II YHR208W BAT1 branched chain amino acid aminotransferase, mitochondrial YIL020C HIS6 5' Pro-FAR isomerase YIL042C YIL042C similarity to rat branched-chain alpha-ketoacid dehydrogenase kinase YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL074C SER33 3-phosphoglycerate dehydrogenase YIL094C LYS12 homo-isocitrate dehydrogenase YIL116W HIS5 histidinol-phosphate aminotransferase YIL167W SDL1 serine dehydratase YIL168W SDL1 serine dehydratase YIR017C MET28 transcriptional activator of sulfur amino acid metabolism YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YIR034C LYS1 saccharopine dehydrogenase YJL071W ARG2 acetylglutamate synthase YJL088W ARG3 ornithine carbamoyltransferase YJR010W MET3 sulfate adenylyltransferase YJR016C ILV3 dihydroxy-acid dehydratase YJR025C BNA1 3-hydroxyanthranilic acid dioxygenase YJR060W CBF1 kinetochore protein YJR078W YJR078W similarity to mammalian indoleamine 2,3-dioxygenase YJR109C CPA2 arginine-specific carbamoylphosphate synthase, large chain YJR130C STR2 similarity to O-succinylhomoserine (thiol)-lyase YJR137C ECM17 involved in cell wall biogenesis and architecture YJR139C HOM6 homoserine dehydrogenase YJR148W BAT2 branched chain amino acid aminotransferase, cytosolic YKL001C MET14 ATP adenosine-5'-phosphosulfate 3'-phosphotransferase YKL015W PUT3 positive activator of the proline utilisation pathway YKL106W AAT1 aspartate transaminase, mitochondrial YKL112W ABF1 ARS-binding factor YKL124W SSH4 suppressor of SHR3 YKL157W APE2 aminopeptidase yscII YKL181W PRS1 ribose-phosphate pyrophosphokinase YKL191W DPH2 diphtheria toxin resistance protein YKL211C TRP3 anthranilate synthase component II YKL215C YKL215C similarity to P. aeruginosa hyuA and hyuB YKL218C SRY1 strong similarity to E.coli and H.influenzae threonine dehydratases YKR039W GAP1 general amino acid permease YKR099W BAS1 transcription factor YLL058W YLL058W similarity to N.crassa O-succinylhomoserine (thiol)-lyase YLL061W MMP1 high affinity S-methylmethionine permease YLR027C AAT2 aspartate aminotransferase, cytosolic YLR089C YLR089C strong similarity to alanine transaminases YLR092W SUL2 sulfate transporter YLR098C CHA4 transcription factor YLR142W PUT1 proline oxidase YLR155C ASP3A L-asparaginase II YLR157C ASP3B L-asparaginase II YLR158C ASP3C L-asparaginase II YLR160C ASP3D L-asparaginase II YLR172C DPH5 diphthamide methyltransferase YLR180W SAM1 S-adenosylmethionine synthetase 1 YLR231C YLR231C strong similarity to rat kynureninase YLR299W ECM38 gamma-glutamyltransferase, involved in glutathione synthesis YLR303W MET17 O-acetylhomoserine sulfhydrylase YLR355C ILV5 ketol-acid reducto-isomerase YLR375W STP3 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YLR438W CAR2 ornithine aminotransferase YLR451W LEU3 transcription factor YML004C GLO1 glyoxalase I YML082W YML082W similarity to N.crassa O-succinylhomoserine (thiol)-lyase YML096W YML096W similarity to asparagine synthases YML099C ARG81 transcription factor involved in arginine metabolism YMR042W ARG80 transcription factor involved in arginine metabolism YMR043W MCM1 transcription factor of the MADS box family YMR062C ECM40 acetylornithine acetyltransferase YMR108W ILV2 acetolactate synthase YMR189W GCV2 glycine decarboxylase P subunit YMR250W GAD1 similarity to glutamate decarboxylases YNL103W MET4 transcriptional activator of sulfur metabolism YNL104C LEU4 2-isopropylmalalate synthase YNL236W SIN4 global regulator protein YNL268W LYP1 lysine-specific high-affinity permease YNL270C ALP1 high-affinity permease for basic amino acids YNL277W MET2 homoserine O-acetyltransferase YNL316C PHA2 prephenate dehydratase YNR050C LYS9 saccharopine dehydrogenase (NADP+, L-glutamate forming) YOL020W TAT2 high affinity tryptophan transport protein YOL058W ARG1 argininosuccinate synthetase YOL061W PRS5 ribose-phosphate pyrophosphokinases YOL064C MET22 protein ser/thr phosphatase YOL140W ARG8 acetylornithine aminotransferase YOR040W GLO4 glyoxalase II (hydroxyacylglutathione hydrolase) YOR108W YOR108W strong similarity to LEU4P YOR130C ORT1 ornithine transport protein of mitochondria involved in arginine metabolism, member of the mitochondrial carrier family (MCF) YOR184W SER1 phosphoserine transaminase YOR202W HIS3 imidazoleglycerol-phosphate dehydratase YOR236W DFR1 dihydrofolate reductase YOR280C YOR280C similarity to S.pombe dihydrofolate reductase YOR303W CPA1 arginine-specific carbamoylphosphate synthase, small chain YOR323C PRO2 gamma-glutamyl phosphate reductase YOR348C PUT4 proline and gamma-aminobutyrate permease YOR375C GDH1 glutamate dehydrogenase (NADP+) YPL038W MET31 transcriptional regulator of sulfur amino acid metabolism YPL111W CAR1 arginase YPL265W DIP5 dicarboxylic amino acid permease YPL274W SAM3 high affinity S-adenosylmethionine permease YPR035W GLN1 glutamate--ammonia ligase YPR060C ARO7 chorismate mutase YPR074C TKL1 transketolase 1 YPR145W ASN1 asparagine synthetase YPR167C MET16 3'-phosphoadenylylsulfate reductase amino acid biosynthesis (118 ORFs) 01.01.01 118 YAL004W YAL004W strong similarity to A.klebsiana glutamate dehydrogenase YAL012W CYS3 cystathionine gamma-lyase YBR084W MIS1 C1-tetrahydrofolate synthase precursor, mitochondrial YBR115C LYS2 L-aminoadipate-semialdehyde dehydrogenase, large subunit YBR117C TKL2 transketolase 2 YBR166C TYR1 prephenate dehydrogenase (NADP+) YBR213W MET8 siroheme synthase YBR248C HIS7 glutamine amidotransferase/cyclase YBR249C ARO4 2-dehydro-3-deoxyphosphoheptonate aldolase, tyrosine-inhibited YBR294W SUL1 high-affinity sulfate transport protein YCL009C ILV6 acetolactate synthase, regulatory subunit YCL018W LEU2 beta-isopropyl-malate dehydrogenase YCL030C HIS4 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase/histidinol dehydrogenase YCR053W THR4 threonine synthase (o-p-homoserine p-lyase) YDL131W LYS21 homocitrate synthase YDL171C GLT1 glutamate synthase (NAPDPH) (GOGAT) YDL182W LYS20 homocitrate synthase YDR007W TRP1 phosphoribosylanthranilate isomerase YDR035W ARO3 2-dehydro-3-deoxyphosphoheptonate aldolase, phenylalanine-inhibited YDR111C YDR111C strong similarity to alanine transaminase YDR127W ARO1 arom pentafunctional enzyme YDR158W HOM2 aspartate-semialdehyde dehydrogenase YDR234W LYS4 homoaconitase YDR300C PRO1 glutamate 5-kinase YDR354W TRP4 anthranilate phosphoribosyltransferase YEL038W UTR4 similarity to K.oxytoca enolase-phosphatase E-1 YEL046C GLY1 L-threonine aldolase, low-specific YER023W PRO3 delta 1-pyrroline-5-carboxylate reductase YER052C HOM3 L-aspartate 4-P-transferase YER055C HIS1 ATP phosphoribosyltransferase YER069W ARG5,6 acetylglutamate kinase and acetylglutamyl-phosphate reductase YER081W SER3 3-phosphoglycerate dehydrogenase YER086W ILV1 anabolic serine and threonine dehydratase precursor YER090W TRP2 anthranilate synthase component I YER091C MET6 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase YFL018C LPD1 dihydrolipoamide dehydrogenase precursor YFL030W YFL030W similarity to several transaminases YFR025C HIS2 histidinol phosphatase YFR030W MET10 sulfite reductase flavin-binding subunit YFR055W YFR055W strong similarity to beta-cystathionases YGL009C LEU1 3-isopropylmalate dehydratase YGL026C TRP5 tryptophan synthase YGL125W MET13 putative methylene tetrahydrofolate reductase YGL148W ARO2 chorismate synthase YGL154C LYS5 L-aminoadipate-semialdehyde dehydrogenase, small subunit YGL184C STR3 strong similarity to Emericella nidulans and similarity to other cystathionine beta-lyase and CYS3P YGR012W YGR012W similarity to E.nidulans cysteine synthase YGR019W UGA1 4-aminobutyrate aminotransferase (GABA transaminase) YGR055W MUP1 high affinity methionine permease YGR124W ASN2 asparagine synthetase YGR155W CYS4 cystathionine beta-synthase YGR204W ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YGR208W SER2 phosphoserine phosphatase YHL011C PRS3 ribose-phosphate pyrophosphokinase YHL036W MUP3 very low affinity methionine permease YHR018C ARG4 arginosuccinate lyase YHR025W THR1 homoserine kinase YHR033W YHR033W strong similarity to glutamate 5-kinase YHR037W PUT2 1-pyrroline-5-carboxylate dehydrogenase YHR068W DYS1 deoxyhypusine synthase YHR070W TRM5 strong similarity to N.crassa met-10+ protein YHR112C YHR112C similarity to cystathionine gamma-synthases YHR208W BAT1 branched chain amino acid aminotransferase, mitochondrial YIL020C HIS6 5' Pro-FAR isomerase YIL074C SER33 3-phosphoglycerate dehydrogenase YIL094C LYS12 homo-isocitrate dehydrogenase YIL116W HIS5 histidinol-phosphate aminotransferase YIR034C LYS1 saccharopine dehydrogenase YJL071W ARG2 acetylglutamate synthase YJL088W ARG3 ornithine carbamoyltransferase YJR010W MET3 sulfate adenylyltransferase YJR016C ILV3 dihydroxy-acid dehydratase YJR109C CPA2 arginine-specific carbamoylphosphate synthase, large chain YJR130C STR2 similarity to O-succinylhomoserine (thiol)-lyase YJR137C ECM17 involved in cell wall biogenesis and architecture YJR139C HOM6 homoserine dehydrogenase YJR148W BAT2 branched chain amino acid aminotransferase, cytosolic YKL001C MET14 ATP adenosine-5'-phosphosulfate 3'-phosphotransferase YKL106W AAT1 aspartate transaminase, mitochondrial YKL181W PRS1 ribose-phosphate pyrophosphokinase YKL191W DPH2 diphtheria toxin resistance protein YKL211C TRP3 anthranilate synthase component II YKL215C YKL215C similarity to P. aeruginosa hyuA and hyuB YLL058W YLL058W similarity to N.crassa O-succinylhomoserine (thiol)-lyase YLR027C AAT2 aspartate aminotransferase, cytosolic YLR089C YLR089C strong similarity to alanine transaminases YLR092W SUL2 sulfate transporter YLR142W PUT1 proline oxidase YLR172C DPH5 diphthamide methyltransferase YLR180W SAM1 S-adenosylmethionine synthetase 1 YLR303W MET17 O-acetylhomoserine sulfhydrylase YLR355C ILV5 ketol-acid reducto-isomerase YLR438W CAR2 ornithine aminotransferase YML082W YML082W similarity to N.crassa O-succinylhomoserine (thiol)-lyase YML096W YML096W similarity to asparagine synthases YMR062C ECM40 acetylornithine acetyltransferase YMR108W ILV2 acetolactate synthase YMR250W GAD1 similarity to glutamate decarboxylases YNL104C LEU4 2-isopropylmalalate synthase YNL277W MET2 homoserine O-acetyltransferase YNL316C PHA2 prephenate dehydratase YNR050C LYS9 saccharopine dehydrogenase (NADP+, L-glutamate forming) YOL058W ARG1 argininosuccinate synthetase YOL061W PRS5 ribose-phosphate pyrophosphokinases YOL064C MET22 protein ser/thr phosphatase YOL140W ARG8 acetylornithine aminotransferase YOR108W YOR108W strong similarity to LEU4P YOR184W SER1 phosphoserine transaminase YOR202W HIS3 imidazoleglycerol-phosphate dehydratase YOR236W DFR1 dihydrofolate reductase YOR280C YOR280C similarity to S.pombe dihydrofolate reductase YOR303W CPA1 arginine-specific carbamoylphosphate synthase, small chain YOR323C PRO2 gamma-glutamyl phosphate reductase YPR035W GLN1 glutamate--ammonia ligase YPR060C ARO7 chorismate mutase YPR074C TKL1 transketolase 1 YPR145W ASN1 asparagine synthetase YPR167C MET16 3'-phosphoadenylylsulfate reductase biosynthesis of the aspartate family (1 ORF) 01.01.01.07 1 YDR234W LYS4 homoaconitase biosynthesis of lysine (1 ORF) 01.01.01.07.06 1 YDR234W LYS4 homoaconitase biosynthesis of the cysteine-aromatic group (2 ORFs) 01.01.01.11 2 YDR035W ARO3 2-dehydro-3-deoxyphosphoheptonate aldolase, phenylalanine-inhibited YIL074C SER33 3-phosphoglycerate dehydrogenase biosynthesis of serine (1 ORF) 01.01.01.11.01 1 YIL074C SER33 3-phosphoglycerate dehydrogenase biosynthesis of the pyruvate family (alanine, isoleucine, leucine, valine) and D-alanine (1 ORF) 01.01.01.15 1 YCL009C ILV6 acetolactate synthase, regulatory subunit regulation of amino acid metabolism (33 ORFs) 01.01.04 33 YAL021C CCR4 transcriptional regulator YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YCR028C FEN2 high affinity H+/pantothenate symporter YDL132W CDC53 controls G1/S transition YDR034C LYS14 transcriptional activator of lysine pathway genes YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR159W SAC3 leucine permease transcriptional regulator YDR160W SSY1 transcriptional regulator of several transporter genes YDR173C ARG82 arginine metabolism transcription factor YDR207C UME6 negative transcriptional regulator YDR253C MET32 transcriptional regulator of sulfur amino acid metabolism YDR328C SKP1 kinetochore protein complex CBF3, subunit D YEL009C GCN4 transcriptional activator of amino acid biosynthetic genes YER055C HIS1 ATP phosphoribosyltransferase YFL010W-A AUA1 involved in ammonia regulation of amino acid transport YGL202W ARO8 aromatic amino acid aminotransferase I YHR137W ARO9 aromatic amino acid aminotransferase II YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIR017C MET28 transcriptional activator of sulfur amino acid metabolism YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YJR060W CBF1 kinetochore protein YKL015W PUT3 positive activator of the proline utilisation pathway YKL112W ABF1 ARS-binding factor YKR099W BAS1 transcription factor YLR098C CHA4 transcription factor YLR299W ECM38 gamma-glutamyltransferase, involved in glutathione synthesis YLR451W LEU3 transcription factor YML099C ARG81 transcription factor involved in arginine metabolism YMR042W ARG80 transcription factor involved in arginine metabolism YMR043W MCM1 transcription factor of the MADS box family YNL103W MET4 transcriptional activator of sulfur metabolism YNL236W SIN4 global regulator protein YPL038W MET31 transcriptional regulator of sulfur amino acid metabolism amino acid transport (23 ORFs) 01.01.07 23 YBR068C BAP2 leucine permease, high-affinity (S1) YBR069C TAT1 amino acid permease YBR132C AGP2 amino-acid permease YCL025C AGP1 asparagine and glutamine permease YDL048C STP4 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YDR046C BAP3 valine transporter YDR508C GNP1 high-affinity glutamine permease YEL063C CAN1 amino acid permease YFL055W AGP3 amino acid permease YGR055W MUP1 high affinity methionine permease YGR191W HIP1 histidine permease YHL036W MUP3 very low affinity methionine permease YKL124W SSH4 suppressor of SHR3 YKR039W GAP1 general amino acid permease YLL061W MMP1 high affinity S-methylmethionine permease YLR375W STP3 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YNL268W LYP1 lysine-specific high-affinity permease YNL270C ALP1 high-affinity permease for basic amino acids YOL020W TAT2 high affinity tryptophan transport protein YOR130C ORT1 ornithine transport protein of mitochondria involved in arginine metabolism, member of the mitochondrial carrier family (MCF) YOR348C PUT4 proline and gamma-aminobutyrate permease YPL265W DIP5 dicarboxylic amino acid permease YPL274W SAM3 high affinity S-adenosylmethionine permease amino acid degradation (catabolism) (35 ORFs) 01.01.10 35 YAL044C GCV3 glycine decarboxylase, subunit H YAL062W GDH3 NADP-glutamate dehydrogenase YBL098W YBL098W similarity to human and D.melanogaster kynurenine 3-monooxygenase YBR006W UGA2 succinate semialdehyde dehydrogenase YBR208C DUR1,2 urea amidolyase YCL064C CHA1 L-serine/L-threonine deaminase YDL080C THI3 positive regulation factor of thiamin metabolism YDL215C GDH2 NAD-specific glutamate dehydrogenase (NAD) YDR019C GCV1 glycine decarboxylase, subunit T YDR111C YDR111C strong similarity to alanine transaminase YDR272W GLO2 glyoxalase II (hydroxyacylglutathione hydrolase) YDR321W ASP1 asparaginase YDR502C SAM2 S-adenosylmethionine synthetase 2 YEL046C GLY1 L-threonine aldolase, low-specific YFL030W YFL030W similarity to several transaminases YHR208W BAT1 branched chain amino acid aminotransferase, mitochondrial YIL042C YIL042C similarity to rat branched-chain alpha-ketoacid dehydrogenase kinase YIL167W SDL1 serine dehydratase YIL168W SDL1 serine dehydratase YJR025C BNA1 3-hydroxyanthranilic acid dioxygenase YJR078W YJR078W similarity to mammalian indoleamine 2,3-dioxygenase YJR148W BAT2 branched chain amino acid aminotransferase, cytosolic YKL218C SRY1 strong similarity to E.coli and H.influenzae threonine dehydratases YLR142W PUT1 proline oxidase YLR155C ASP3A L-asparaginase II YLR157C ASP3B L-asparaginase II YLR158C ASP3C L-asparaginase II YLR160C ASP3D L-asparaginase II YLR180W SAM1 S-adenosylmethionine synthetase 1 YLR231C YLR231C strong similarity to rat kynureninase YML004C GLO1 glyoxalase I YMR189W GCV2 glycine decarboxylase P subunit YOR040W GLO4 glyoxalase II (hydroxyacylglutathione hydrolase) YOR375C GDH1 glutamate dehydrogenase (NADP+) YPL111W CAR1 arginase degradation of amino acids of the glutamate group (1 ORF) 01.01.10.01 1 YAL062W GDH3 NADP-glutamate dehydrogenase degradation of glutamate (1 ORF) 01.01.10.01.04 1 YAL062W GDH3 NADP-glutamate dehydrogenase degradation of amino acids of the cysteine-aromatic group (1 ORF) 01.01.10.05 1 YAL044C GCV3 glycine decarboxylase, subunit H degradation of glycine (1 ORF) 01.01.10.05.04 1 YAL044C GCV3 glycine decarboxylase, subunit H other amino acid metabolism activities (5 ORFs) 01.01.99 5 YDR465C RMT2 N-delta-arginine methyltransferase YER042W MXR1 responsible for the reduction of methionine sulfoxide YFR018C YFR018C similarity to human glutaminyl-peptide cyclotransferase YGL017W ATE1 arginyl tRNA transferase YKL157W APE2 aminopeptidase yscII nitrogen and sulfur metabolism (67 ORFs) 01.02 67 YAL062W GDH3 NADP-glutamate dehydrogenase YBR208C DUR1,2 urea amidolyase YBR213W MET8 siroheme synthase YCR028C FEN2 high affinity H+/pantothenate symporter YDL170W UGA3 transcriptional activator for GABA catabolic genes YDL171C GLT1 glutamate synthase (NAPDPH) (GOGAT) YDL210W UGA4 GABA-specific high-affinity permease YDL215C GDH2 NAD-specific glutamate dehydrogenase (NAD) YDR111C YDR111C strong similarity to alanine transaminase YDR207C UME6 negative transcriptional regulator YDR242W AMD2 amidase YDR253C MET32 transcriptional regulator of sulfur amino acid metabolism YDR353W TRR1 thioredoxin reductase (NADPH) YEL062W NPR2 nitrogen permease regulator YER040W GLN3 transcription factor for positive nitrogen regulation YFL010W-A AUA1 involved in ammonia regulation of amino acid transport YFL021W GAT1 transcription factor for nitrogen regulation YFL030W YFL030W similarity to several transaminases YFL061W YFL061W similarity to M.verrucaria cyanamide hydratase YFR030W MET10 sulfite reductase flavin-binding subunit YGL254W FZF1 sulfite resistance protein YGR019W UGA1 4-aminobutyrate aminotransferase (GABA transaminase) YHR106W TRR2 thioredoxin reductase YHR176W FMO flavin-containing monooxygenase YIR017C MET28 transcriptional activator of sulfur amino acid metabolism YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YIR027C DAL1 allantoinase YIR029W DAL2 allantoinase YIR030C DCG1 involved in nitrogen-catabolite metabolism YIR032C DAL3 ureidoglycolate hydrolase YJL060W YJL060W similarity to kynurenine aminotransferase and glutamine-phenylpyruvate transaminase YJL110C GZF3 transcriptional repressor YJL126W NIT2 nitrilase YJL172W CPS1 Gly-X carboxypeptidase YSCS precursor YJR010W MET3 sulfate adenylyltransferase YJR060W CBF1 kinetochore protein YJR137C ECM17 involved in cell wall biogenesis and architecture YJR149W YJR149W similarity to 2-nitropropane dioxygenase YKL001C MET14 ATP adenosine-5'-phosphosulfate 3'-phosphotransferase YKL040C NFU1 iron homeostasis YKL112W ABF1 ARS-binding factor YKR034W DAL80 transcriptional repressor for allantoin and GABA catabolic genes YLR013W GAT3 weak similarity to nitrogen regulatory proteins YLR027C AAT2 aspartate aminotransferase, cytosolic YLR089C YLR089C strong similarity to alanine transaminases YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR351C NIT3 nitrilase YLR438W CAR2 ornithine aminotransferase YML099C ARG81 transcription factor involved in arginine metabolism YMR042W ARG80 transcription factor involved in arginine metabolism YMR043W MCM1 transcription factor of the MADS box family YMR293C YMR293C similarity to amidases YNL103W MET4 transcriptional activator of sulfur metabolism YNL183C NPR1 ser/thr protein kinase YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL229C URE2 nitrogen catabolite repression regulator YNL335W YNL335W similarity to M.verrucaria cyanamide hydratase, identical to hypothetical protein YFL061w YOL058W ARG1 argininosuccinate synthetase YOL153C YOL153C strong similarity to CPS1P YOR226C ISU2 strong similarity to nitrogen fixation proteins YOR251C YOR251C similarity to thiosulfate sulfurtransferases YOR375C GDH1 glutamate dehydrogenase (NADP+) YPL038W MET31 transcriptional regulator of sulfur amino acid metabolism YPL111W CAR1 arginase YPL135W ISU1 strong similarity to nitrogen fixation protein (nifU) YPR035W GLN1 glutamate--ammonia ligase YPR167C MET16 3'-phosphoadenylylsulfate reductase nitrogen and sulfur utilization (38 ORFs) 01.02.01 38 YAL062W GDH3 NADP-glutamate dehydrogenase YBR208C DUR1,2 urea amidolyase YDL171C GLT1 glutamate synthase (NAPDPH) (GOGAT) YDL210W UGA4 GABA-specific high-affinity permease YDL215C GDH2 NAD-specific glutamate dehydrogenase (NAD) YDR111C YDR111C strong similarity to alanine transaminase YDR242W AMD2 amidase YDR353W TRR1 thioredoxin reductase (NADPH) YFL030W YFL030W similarity to several transaminases YFL061W YFL061W similarity to M.verrucaria cyanamide hydratase YFR030W MET10 sulfite reductase flavin-binding subunit YHR106W TRR2 thioredoxin reductase YHR176W FMO flavin-containing monooxygenase YIR027C DAL1 allantoinase YIR029W DAL2 allantoinase YIR032C DAL3 ureidoglycolate hydrolase YJL060W YJL060W similarity to kynurenine aminotransferase and glutamine-phenylpyruvate transaminase YJL126W NIT2 nitrilase YJL172W CPS1 Gly-X carboxypeptidase YSCS precursor YJR010W MET3 sulfate adenylyltransferase YJR137C ECM17 involved in cell wall biogenesis and architecture YJR149W YJR149W similarity to 2-nitropropane dioxygenase YKL001C MET14 ATP adenosine-5'-phosphosulfate 3'-phosphotransferase YKL040C NFU1 iron homeostasis YLR027C AAT2 aspartate aminotransferase, cytosolic YLR089C YLR089C strong similarity to alanine transaminases YLR351C NIT3 nitrilase YLR438W CAR2 ornithine aminotransferase YMR293C YMR293C similarity to amidases YNL335W YNL335W similarity to M.verrucaria cyanamide hydratase, identical to hypothetical protein YFL061w YOL058W ARG1 argininosuccinate synthetase YOL153C YOL153C strong similarity to CPS1P YOR226C ISU2 strong similarity to nitrogen fixation proteins YOR251C YOR251C similarity to thiosulfate sulfurtransferases YOR375C GDH1 glutamate dehydrogenase (NADP+) YPL135W ISU1 strong similarity to nitrogen fixation protein (nifU) YPR035W GLN1 glutamate--ammonia ligase YPR167C MET16 3'-phosphoadenylylsulfate reductase regulation of nitrogen and sulphur utilization (29 ORFs) 01.02.04 29 YBR213W MET8 siroheme synthase YCR028C FEN2 high affinity H+/pantothenate symporter YDL170W UGA3 transcriptional activator for GABA catabolic genes YDR207C UME6 negative transcriptional regulator YDR253C MET32 transcriptional regulator of sulfur amino acid metabolism YEL062W NPR2 nitrogen permease regulator YER040W GLN3 transcription factor for positive nitrogen regulation YFL010W-A AUA1 involved in ammonia regulation of amino acid transport YFL021W GAT1 transcription factor for nitrogen regulation YGL254W FZF1 sulfite resistance protein YGR019W UGA1 4-aminobutyrate aminotransferase (GABA transaminase) YIR017C MET28 transcriptional activator of sulfur amino acid metabolism YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YIR030C DCG1 involved in nitrogen-catabolite metabolism YJL110C GZF3 transcriptional repressor YJR060W CBF1 kinetochore protein YKL112W ABF1 ARS-binding factor YKR034W DAL80 transcriptional repressor for allantoin and GABA catabolic genes YLR013W GAT3 weak similarity to nitrogen regulatory proteins YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YML099C ARG81 transcription factor involved in arginine metabolism YMR042W ARG80 transcription factor involved in arginine metabolism YMR043W MCM1 transcription factor of the MADS box family YNL103W MET4 transcriptional activator of sulfur metabolism YNL183C NPR1 ser/thr protein kinase YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL229C URE2 nitrogen catabolite repression regulator YPL038W MET31 transcriptional regulator of sulfur amino acid metabolism YPL111W CAR1 arginase nucleotide metabolism (148 ORFs) 01.03 148 YAL022C FUN26 intracellular membrane protein involved in nucleoside transport YAR015W ADE1 phosphoribosylamidoimidazole-succinocarboxamide synthase YAR073W IMD1 strong similarity to IMP dehydrogenases YAR075W YAR075W strong similarity to IMP dehydrogenases YBL030C PET9 ADP/ATP carrier protein (MCF) YBL039C URA7 CTP synthase 1 YBL042C FUI1 uridine transport protein YBL068W PRS4 ribose-phosphate pyrophosphokinase 3 YBR014C YBR014C similarity to glutaredoxin YBR021W FUR4 uracil permease YBR084W MIS1 C1-tetrahydrofolate synthase precursor, mitochondrial YBR085W AAC3 ADP/ATP carrier protein (MCF) YBR111C YSA1 sugar-nucleotide hydrolase YBR208C DUR1,2 urea amidolyase YBR252W DUT1 dUTP pyrophosphatase precursor YBR263W SHM1 serine hydroxymethyltransferase precursor, mitochondrial YBR284W YBR284W similarity to AMP deaminase YCL050C APA1 ATP adenylyltransferase I YDL010W YDL010W similarity to hypothetical protein YBR014c and glutaredoxins YDL106C PHO2 homeodomain protein YDL125C HNT1 similarity to protein kinase C inhibitor-I YDL244W THI13 strong similarity to THI5P, YJR156c, YNL332w and A. parasiticus, S.pombe NMT1 protein YDR020C YDR020C weak similarity to uridine kinases and phosphoribulokinases YDR226W ADK1 adenylate kinase, cytosolic YDR305C HNT2 dinucleoside 5',5 YDR353W TRR1 thioredoxin reductase (NADPH) YDR399W HPT1 hypoxanthine guanine phosphoribosyl transferase YDR400W URH1 uridine ribohydrolase (EC 3.2.2.1) YDR408C ADE8 phosphoribosylglycinamide formyltransferase (GART) YDR441C APT2 adenine phosphoribosyltransferase YDR454C GUK1 guanylate kinase YDR513W TTR1 glutaredoxin YDR530C APA2 ATP adenylyltransferase II YEL021W URA3 orotidine-5'-phosphate decarboxylase YEL034W HYP2 translation initiation factor eIF5A.1 YER056C FCY2 purine-cytosine permease YER060W FCY21 purine-cytosine permease YER060W-A FCY22 purine/cytosine permease with similarity to FCY2P YER070W RNR1 ribonucleoside-diphosphate reductase, large subunit YER099C PRS2 ribose-phosphate pyrophosphokinase YER170W ADK2 adenylate kinase, mitochondrial YFL058W THI5 pyrimidine biosynthesis protein YGL063W PUS2 pseudouridine synthase 2 YGL067W NPY1 NADH pyrophosphatase I of the Nudix family of hydrolases, has a peroxisomal targeting signal YGL173C KEM1 multifunctional nuclease YGL186C YGL186C similarity to hypothetical protein FCY21P and weak similarity to FCY2 protein YGL234W ADE5,7 phosphoribosylamine-glycine ligase and phosphoribosylformylglycinamidine cyclo-ligase YGL248W PDE1 low affinity 3',5'-cyclic-nucleotide phosphodiesterase YGR061C ADE6 5'-phosphoribosylformyl glycinamidine synthetase YGR072W UPF3 nonsense-mediated mRNA decay protein YGR096W YGR096W hypothetical mitochondrial transport protein YGR180C RNR4 ribonucleotide reductase small subunit YGR195W SKI6 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YGR204W ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YGR276C RNH70 ribonuclease H YHL011C PRS3 ribose-phosphate pyrophosphokinase YHR002W YHR002W similarity to bovine mitochondrial carrier protein/Grave's disease carrier protein YHR077C NMD2 nonsense-mediated mRNA decay protein 2 YHR106W TRR2 thioredoxin reductase YHR128W FUR1 uracil phosphoribosyltransferase YHR144C DCD1 deoxycytidylate deaminase YHR216W IMD2 IMP dehydrogenase YIL066C RNR3 ribonucleotide reductase, repair inducible large subunit YIL078W THS1 threonyl tRNA synthetase, cytosolic YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YIR027C DAL1 allantoinase YIR029W DAL2 allantoinase YIR031C DAL7 malate synthase 2 YIR032C DAL3 ureidoglycolate hydrolase YJL005W CYR1 adenylate cyclase YJL026W RNR2 ribonucleoside-diphosphate reductase, small subunit YJL070C YJL070C similarity to AMP deaminases YJL130C URA2 multifunctional pyrimidine biosynthesis protein YJL208C NUC1 nuclease, mitochondrial YJR057W CDC8 dTMP kinase YJR103W URA8 CTP synthase 2 YJR105W ADO1 strong similarity to human adenosine kinase YJR132W NMD5 NAM7P interacting protein YJR133W XPT1 xanthine phosphoribosyl transferase YJR156C THI11 thiamine regulated gene, homologous to nmt1a in S. pombe YKL009W MRT4 mRNA turnover 4 YKL024C URA6 uridine-monophosphate kinase YKL067W YNK1 nucleoside diphosphate kinase YKL149C DBR1 lariat-debranching enzyme YKL181W PRS1 ribose-phosphate pyrophosphokinase YKL216W URA1 dihydroorotate dehydrogenase YKR080W MTD1 methylenetetrahydrofolate dehydrogenase (NAD+) YKR099W BAS1 transcription factor YLL013C PUF3 transcript-specific regulator of mRNA degradation YLR014C PPR1 transcription factor regulating pyrimidine pathway YLR017W MEU1 multiple enhancer of UAS2 YLR028C ADE16 5-aminoimidazole-4-carboxamide ribotide transformylase YLR058C SHM2 serine hydroxymethyltransferase, cytoplasmic YLR107W REX3 RNA exonuclease, member of the family of 3' -5' exonucleases YLR165C PUS5 RNA:pseudouridine (Psi)-synthase YLR209C PNP1 strong similarity to purine-nucleoside phosphorylases YLR245C CDD1 cytidine deaminase YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR359W ADE13 adenylosuccinate lyase YLR363C NMD4 NAM7P interacting protein YLR420W URA4 dihydroorotase YLR432W IMD3 strong similarity to IMP dehydrogenases, Pur5p and YML056c YML022W APT1 adenine phosphoribosyltransferase YML035C AMD1 AMP deaminase YML056C IMD4 strong similarity to IMP dehydrogenases YML058W SML1 protein inhibitor of ribonucleotide reductase YML106W URA5 orotate phosphoribosyltransferase YMR056C AAC1 ADP/ATP carrier protein (MCF) YMR080C NAM7 nonsense-mediated mRNA decay protein YMR081C ISF1 involved in suppression of mitochondrial splicing defect YMR120C ADE17 5-aminoimidazole-4-carboxamide ribotide transformylase YMR217W GUA1 GMP synthase (glutamine-hydrolyzing) YMR234W RNH1 ribonuclease H YMR271C URA10 orotate phosphoribosyltransferase2 YMR287C MSU1 3'-5' exonuclease for RNA 3' ss-tail, mitochondrial YMR300C ADE4 amidophosphoribosyltransferase YNL072W RNH35 RNase H(35), a 35 kDa ribonuclease H YNL076W MKS1 pleiotropic regulatory factor YNL098C RAS2 GTP-binding protein YNL141W AAH1 adenosine deaminase YNL220W ADE12 adenylosuccinate synthetase YNL232W CSL4 core component of the 3'-5' exosome YNL243W SLA2 cytoskeleton assembly control protein YNL292W PUS4 pseudouridine synthase YNL314W DAL82 transcriptional activator for allantoin catabolic genes YNL332W THI12 nearly identical to THI5P, THI11 and YDL244w YNR012W URK1 uridine kinase YOL061W PRS5 ribose-phosphate pyrophosphokinases YOL081W IRA2 GTPase-activating protein for RAS proteins YOL110W SHR5 RAS suppressor YOR033C EXO1 exonuclease which interacts with MSH2P YOR071C YOR071C strong similarity to Thi10p YOR074C CDC21 thymidylate synthase YOR076C SKI7 GTPase with function in 3'-to-5' degradation of mRNA YOR101W RAS1 GTP-binding protein YOR128C ADE2 phosphoribosylaminoimidazole carboxylase YOR192C YOR192C strong similarity to Thi10p YOR222W ODC2 similarity to ADP/ATP carrier proteins YOR236W DFR1 dihydrofolate reductase YOR280C YOR280C similarity to S.pombe dihydrofolate reductase YOR360C PDE2 high affinity 3',5'-cyclic-nucleotide phosphodiesterase YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL123C RNY1 similarity to ribonucleases YPL212C PUS1 pseudouridine synthase 1 YPR011C YPR011C similarity to ADP/ATP carrier proteins and Graves disease carrier protein YPR062W FCY1 cytosine deaminase Q0055 AI2 COX1 intron 2 protein Q0060 AI3 DNA endonuclease purine ribonucleotide metabolism (45 ORFs) 01.03.01 45 YAR015W ADE1 phosphoribosylamidoimidazole-succinocarboxamide synthase YAR073W IMD1 strong similarity to IMP dehydrogenases YAR075W YAR075W strong similarity to IMP dehydrogenases YBL068W PRS4 ribose-phosphate pyrophosphokinase 3 YBR084W MIS1 C1-tetrahydrofolate synthase precursor, mitochondrial YBR208C DUR1,2 urea amidolyase YBR263W SHM1 serine hydroxymethyltransferase precursor, mitochondrial YBR284W YBR284W similarity to AMP deaminase YDR020C YDR020C weak similarity to uridine kinases and phosphoribulokinases YDR399W HPT1 hypoxanthine guanine phosphoribosyl transferase YDR400W URH1 uridine ribohydrolase (EC 3.2.2.1) YDR408C ADE8 phosphoribosylglycinamide formyltransferase (GART) YDR441C APT2 adenine phosphoribosyltransferase YER099C PRS2 ribose-phosphate pyrophosphokinase YGL234W ADE5,7 phosphoribosylamine-glycine ligase and phosphoribosylformylglycinamidine cyclo-ligase YGR061C ADE6 5'-phosphoribosylformyl glycinamidine synthetase YGR204W ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YHL011C PRS3 ribose-phosphate pyrophosphokinase YHR216W IMD2 IMP dehydrogenase YIR027C DAL1 allantoinase YIR029W DAL2 allantoinase YIR031C DAL7 malate synthase 2 YIR032C DAL3 ureidoglycolate hydrolase YJL070C YJL070C similarity to AMP deaminases YJR105W ADO1 strong similarity to human adenosine kinase YKL181W PRS1 ribose-phosphate pyrophosphokinase YKR080W MTD1 methylenetetrahydrofolate dehydrogenase (NAD+) YLR017W MEU1 multiple enhancer of UAS2 YLR028C ADE16 5-aminoimidazole-4-carboxamide ribotide transformylase YLR058C SHM2 serine hydroxymethyltransferase, cytoplasmic YLR209C PNP1 strong similarity to purine-nucleoside phosphorylases YLR359W ADE13 adenylosuccinate lyase YLR432W IMD3 strong similarity to IMP dehydrogenases, Pur5p and YML056c YML022W APT1 adenine phosphoribosyltransferase YML035C AMD1 AMP deaminase YML056C IMD4 strong similarity to IMP dehydrogenases YMR120C ADE17 5-aminoimidazole-4-carboxamide ribotide transformylase YMR217W GUA1 GMP synthase (glutamine-hydrolyzing) YMR300C ADE4 amidophosphoribosyltransferase YNL141W AAH1 adenosine deaminase YNL220W ADE12 adenylosuccinate synthetase YOL061W PRS5 ribose-phosphate pyrophosphokinases YOR128C ADE2 phosphoribosylaminoimidazole carboxylase YOR236W DFR1 dihydrofolate reductase YOR280C YOR280C similarity to S.pombe dihydrofolate reductase pyrimidine ribonucleotide metabolism (29 ORFs) 01.03.04 29 YBL039C URA7 CTP synthase 1 YBL042C FUI1 uridine transport protein YBL068W PRS4 ribose-phosphate pyrophosphokinase 3 YBR021W FUR4 uracil permease YBR252W DUT1 dUTP pyrophosphatase precursor YDL244W THI13 strong similarity to THI5P, YJR156c, YNL332w and A. parasiticus, S.pombe NMT1 protein YEL021W URA3 orotidine-5'-phosphate decarboxylase YER099C PRS2 ribose-phosphate pyrophosphokinase YFL058W THI5 pyrimidine biosynthesis protein YHL011C PRS3 ribose-phosphate pyrophosphokinase YHR128W FUR1 uracil phosphoribosyltransferase YHR144C DCD1 deoxycytidylate deaminase YJL130C URA2 multifunctional pyrimidine biosynthesis protein YJR057W CDC8 dTMP kinase YJR103W URA8 CTP synthase 2 YJR133W XPT1 xanthine phosphoribosyl transferase YJR156C THI11 thiamine regulated gene, homologous to nmt1a in S. pombe YKL024C URA6 uridine-monophosphate kinase YKL181W PRS1 ribose-phosphate pyrophosphokinase YKL216W URA1 dihydroorotate dehydrogenase YLR245C CDD1 cytidine deaminase YLR420W URA4 dihydroorotase YML106W URA5 orotate phosphoribosyltransferase YMR271C URA10 orotate phosphoribosyltransferase2 YNL332W THI12 nearly identical to THI5P, THI11 and YDL244w YNR012W URK1 uridine kinase YOL061W PRS5 ribose-phosphate pyrophosphokinases YOR280C YOR280C similarity to S.pombe dihydrofolate reductase YPR062W FCY1 cytosine deaminase deoxyribonucleotide metabolism (11 ORFs) 01.03.07 11 YBR014C YBR014C similarity to glutaredoxin YDL010W YDL010W similarity to hypothetical protein YBR014c and glutaredoxins YDR353W TRR1 thioredoxin reductase (NADPH) YDR513W TTR1 glutaredoxin YER070W RNR1 ribonucleoside-diphosphate reductase, large subunit YGR180C RNR4 ribonucleotide reductase small subunit YHR106W TRR2 thioredoxin reductase YIL066C RNR3 ribonucleotide reductase, repair inducible large subunit YJL026W RNR2 ribonucleoside-diphosphate reductase, small subunit YML058W SML1 protein inhibitor of ribonucleotide reductase YOR074C CDC21 thymidylate synthase metabolism of cyclic and unusual nucleotides (8 ORFs) 01.03.10 8 YCL050C APA1 ATP adenylyltransferase I YDR530C APA2 ATP adenylyltransferase II YGL063W PUS2 pseudouridine synthase 2 YJL005W CYR1 adenylate cyclase YNL292W PUS4 pseudouridine synthase YOL081W IRA2 GTPase-activating protein for RAS proteins YOR360C PDE2 high affinity 3',5'-cyclic-nucleotide phosphodiesterase YPL212C PUS1 pseudouridine synthase 1 regulation of nucleotide metabolism (13 ORFs) 01.03.13 13 YDL106C PHO2 homeodomain protein YER056C FCY2 purine-cytosine permease YGL248W PDE1 low affinity 3',5'-cyclic-nucleotide phosphodiesterase YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YKR099W BAS1 transcription factor YLR014C PPR1 transcription factor regulating pyrimidine pathway YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YNL076W MKS1 pleiotropic regulatory factor YNL098C RAS2 GTP-binding protein YNL314W DAL82 transcriptional activator for allantoin catabolic genes YOL081W IRA2 GTPase-activating protein for RAS proteins YOL110W SHR5 RAS suppressor YOR101W RAS1 GTP-binding protein polynucleotide degradation (27 ORFs) 01.03.16 27 YEL034W HYP2 translation initiation factor eIF5A.1 YGL173C KEM1 multifunctional nuclease YGR072W UPF3 nonsense-mediated mRNA decay protein YGR195W SKI6 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YGR276C RNH70 ribonuclease H YHR077C NMD2 nonsense-mediated mRNA decay protein 2 YIL078W THS1 threonyl tRNA synthetase, cytosolic YJL208C NUC1 nuclease, mitochondrial YJR132W NMD5 NAM7P interacting protein YKL009W MRT4 mRNA turnover 4 YKL149C DBR1 lariat-debranching enzyme YLL013C PUF3 transcript-specific regulator of mRNA degradation YLR107W REX3 RNA exonuclease, member of the family of 3' -5' exonucleases YLR363C NMD4 NAM7P interacting protein YMR080C NAM7 nonsense-mediated mRNA decay protein YMR081C ISF1 involved in suppression of mitochondrial splicing defect YMR234W RNH1 ribonuclease H YMR287C MSU1 3'-5' exonuclease for RNA 3' ss-tail, mitochondrial YNL072W RNH35 RNase H(35), a 35 kDa ribonuclease H YNL232W CSL4 core component of the 3'-5' exosome YNL243W SLA2 cytoskeleton assembly control protein YOR033C EXO1 exonuclease which interacts with MSH2P YOR076C SKI7 GTPase with function in 3'-to-5' degradation of mRNA YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL123C RNY1 similarity to ribonucleases Q0055 AI2 COX1 intron 2 protein Q0060 AI3 DNA endonuclease RNA degradation (4 ORFs) 01.03.16.01 4 YLL013C PUF3 transcript-specific regulator of mRNA degradation YLR107W REX3 RNA exonuclease, member of the family of 3' -5' exonucleases YNL232W CSL4 core component of the 3'-5' exosome YOR076C SKI7 GTPase with function in 3'-to-5' degradation of mRNA nucleotide transport (14 ORFs) 01.03.19 14 YAL022C FUN26 intracellular membrane protein involved in nucleoside transport YBL030C PET9 ADP/ATP carrier protein (MCF) YBR085W AAC3 ADP/ATP carrier protein (MCF) YER056C FCY2 purine-cytosine permease YER060W FCY21 purine-cytosine permease YER060W-A FCY22 purine/cytosine permease with similarity to FCY2P YGL186C YGL186C similarity to hypothetical protein FCY21P and weak similarity to FCY2 protein YGR096W YGR096W hypothetical mitochondrial transport protein YHR002W YHR002W similarity to bovine mitochondrial carrier protein/Grave's disease carrier protein YMR056C AAC1 ADP/ATP carrier protein (MCF) YOR071C YOR071C strong similarity to Thi10p YOR192C YOR192C strong similarity to Thi10p YOR222W ODC2 similarity to ADP/ATP carrier proteins YPR011C YPR011C similarity to ADP/ATP carrier proteins and Graves disease carrier protein other nucleotide-metabolism activities (7 ORFs) 01.03.99 7 YBR111C YSA1 sugar-nucleotide hydrolase YDL125C HNT1 similarity to protein kinase C inhibitor-I YDR226W ADK1 adenylate kinase, cytosolic YDR305C HNT2 dinucleoside 5',5 YDR454C GUK1 guanylate kinase YER170W ADK2 adenylate kinase, mitochondrial YKL067W YNK1 nucleoside diphosphate kinase phosphate metabolism (33 ORFs) 01.04 33 YAR071W PHO11 secreted acid phosphatase YBR011C IPP1 inorganic pyrophosphatase, cytoplasmic YBR092C PHO3 constitutive acid phosphatase precursor YBR093C PHO5 repressible acid phosphatase precursor YBR106W PHO88 involved in phosphate transport YBR243C ALG7 UDP-N-acetylglucosamine-1-phosphate transferase YBR296C PHO89 Na+-coupled phosphate transport protein, high affinity YCR037C PHO87 member of the phosphate permease family YDL024C DIA3 strong similarity to acid phosphatase YDL106C PHO2 homeodomain protein YDL236W PHO13 4-nitrophenylphosphatase YDR481C PHO8 repressible alkaline phosphatase vacuolar YER053C YER053C strong similarity to mitochondrial phosphate carrier protein YFL004W VTC2 putative polyphosphate synthetase YFR034C PHO4 transcription factor YGR233C PHO81 cyclin-dependent kinase inhibitor YHR043C DOG2 2-deoxyglucose-6-phosphate phosphatase YHR044C DOG1 2-deoxyglucose-6-phosphate phosphatase YHR201C PPX1 exopolyphosphatase YHR215W PHO12 secreted acid phosphatase YJL117W PHO86 inorganic phospate transporter YJL198W PHO90 low affinity phosphate transporter YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YLR348C DIC1 dicarboxylate carrier protein YML121W GTR1 GTP-binding protein YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YMR267W PPA2 inorganic pyrophosphatase, mitochondrial YMR282C AEP2 required for the expression of subunit-9 of atp synthase YNL330C RPD3 histone deacetylase B YNR013C PHO91 similarity to PHO87P and PHO90P YOL001W PHO80 cyclin YPL031C PHO85 cyclin-dependent protein kinase YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD phosphate utilization (14 ORFs) 01.04.01 14 YAR071W PHO11 secreted acid phosphatase YBR011C IPP1 inorganic pyrophosphatase, cytoplasmic YBR092C PHO3 constitutive acid phosphatase precursor YBR093C PHO5 repressible acid phosphatase precursor YBR243C ALG7 UDP-N-acetylglucosamine-1-phosphate transferase YDL024C DIA3 strong similarity to acid phosphatase YDR481C PHO8 repressible alkaline phosphatase vacuolar YHR043C DOG2 2-deoxyglucose-6-phosphate phosphatase YHR044C DOG1 2-deoxyglucose-6-phosphate phosphatase YHR201C PPX1 exopolyphosphatase YHR215W PHO12 secreted acid phosphatase YMR267W PPA2 inorganic pyrophosphatase, mitochondrial YMR282C AEP2 required for the expression of subunit-9 of atp synthase YNL330C RPD3 histone deacetylase B regulation of phosphate utilization (8 ORFs) 01.04.04 8 YBR106W PHO88 involved in phosphate transport YDL106C PHO2 homeodomain protein YFR034C PHO4 transcription factor YGR233C PHO81 cyclin-dependent kinase inhibitor YML121W GTR1 GTP-binding protein YOL001W PHO80 cyclin YPL031C PHO85 cyclin-dependent protein kinase YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD phosphate transport (10 ORFs) 01.04.07 10 YBR106W PHO88 involved in phosphate transport YBR296C PHO89 Na+-coupled phosphate transport protein, high affinity YCR037C PHO87 member of the phosphate permease family YER053C YER053C strong similarity to mitochondrial phosphate carrier protein YJL117W PHO86 inorganic phospate transporter YJL198W PHO90 low affinity phosphate transporter YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YLR348C DIC1 dicarboxylate carrier protein YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YNR013C PHO91 similarity to PHO87P and PHO90P other phosphate metabolism activities (1 ORF) 01.04.99 1 YDL236W PHO13 4-nitrophenylphosphatase C-compound and carbohydrate metabolism (415 ORFs) 01.05 415 YAL021C CCR4 transcriptional regulator YAL023C PMT2 mannosyltransferase YAL038W CDC19 pyruvate kinase YAL054C ACS1 acetyl-CoA synthetase YAL060W BDH1 stereospecific (2R, 3R)-2,3-butanediol dehydrogenase YAL061W FUN50 similarity to alcohol/sorbitol dehydrogenase YBL001C ECM15 involved in cell wall biogenesis and architecture YBL061C SKT5 protoplast regeneration and killer toxin resistance protein YBL082C RHK1 mannosyltransferase YBL086C YBL086C weak similarity to S. pombe hypothetical protein YBL103C RTG3 bHLH/zip transcription factor that regulates CIT2 gene expression YBR001C NTH2 alpha,alpha-trehalase YBR018C GAL7 UDP-glucose--hexose-1-phosphate uridylyltransferase YBR019C GAL10 UDP-glucose 4-epimerase YBR020W GAL1 galactokinase YBR023C CHS3 chitin synthase III YBR030W YBR030W weak similarity to regulatory protein MSR1P YBR038W CHS2 chitin synthase II YBR050C REG2 regulatory subunit of type I protein phosphatase YBR056W YBR056W similarity to glucan 1,3-beta-glucosidase YBR084W MIS1 C1-tetrahydrofolate synthase precursor, mitochondrial YBR110W ALG1 beta-mannosyltransferase YBR117C TKL2 transketolase 2 YBR126C TPS1 alpha,alpha-trehalose-phosphate synthase, 56 KD subunit YBR145W ADH5 alcohol dehydrogenase V YBR149W ARA1 D-arabinose dehydrogenase, large subunit YBR196C PGI1 glucose-6-phosphate isomerase YBR199W KTR4 alpha-1,2-mannosyltransferase YBR205W KTR3 alpha-1,2-mannosyltransferase YBR218C PYC2 pyruvate carboxylase 2 YBR221C PDB1 pyruvate dehydrogenase (lipoamide) beta chain precursor YBR229C ROT2 glucosidase II, catalytic subunit YBR241C YBR241C similarity to glucose transport proteins YBR243C ALG7 UDP-N-acetylglucosamine-1-phosphate transferase YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR289W SNF5 component of SWI/SNF transcription activator complex YBR291C CTP1 citrate transport protein, mitochondrial (MCF) YBR297W MAL33 maltose fermentation regulatory protein YBR298C MAL31 maltose permease YBR299W MAL32 alpha-glucosidase YCL040W GLK1 aldohexose specific glucokinase YCR002C CDC10 cell division control protein YCR005C CIT2 citrate (si)-synthase, peroxisomal YCR010C ADY2 strong similarity to Y.lipolytica GPR1 protein and FUN34P YCR012W PGK1 phosphoglycerate kinase YCR028C FEN2 high affinity H+/pantothenate symporter YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR036W RBK1 ribokinase YCR081W SRB8 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YCR105W YCR105W strong similarity to alcohol dehydrogenases YCR107W AAD3 strong similarity aryl-alcohol reductases of P. chrysosporium YDL006W PTC1 protein serine/threonine phosphatase 2c YDL013W HEX3 hexose metabolism-related protein YDL021W GPM2 phosphoglycerate mutase YDL022W GPD1 glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic YDL037C YDL037C strong similarity to glucan 1,4-alpha-glucosidase YDL049C KNH1 functional homolog of KRE9 YDL055C PSA1 mannose-1-phosphate guanyltransferase YDL066W IDP1 isocitrate dehydrogenase (NADP+), mitochondrial YDL078C MDH3 malate dehydrogenase, peroxisomal YDL093W PMT5 O-mannosyltransferase similarity to PMT1P-PMT4P YDL095W PMT1 mannosyltransferase YDL124W YDL124W similarity to aldose reductases YDL131W LYS21 homocitrate synthase YDL132W CDC53 controls G1/S transition YDL134C PPH21 protein ser/thr phosphatase PP2A-1 YDL138W RGT2 suppressor of SNF3 mutant YDL168W SFA1 long-chain alcohol dehydrogenase YDL174C DLD1 D-lactate ferricytochrome C oxidoreductase (D-LCR) YDL182W LYS20 homocitrate synthase YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL199C YDL199C similarity to sugar transporter proteins YDL203C YDL203C similarity to SKT5P YDL232W OST4 oligosaccharyltransferase subunit YDL243C AAD4 strong similarity to aryl-alcohol dehydrogenase YDL245C HXT15 strong similarity to HXT17P and HXT7P YDL246C YDL246C strong similarity to SOR1P YDL247W YDL247W strong similarity to sugar transport proteins YDR001C NTH1 neutral trehalase (alpha,alpha-trehalase) YDR009W GAL3 galactokinase YDR028C REG1 regulatory subunit for protein phosphatase GLC7P YDR043C NRG1 transcriptional repressor for glucose repression of STA1 gene expression YDR050C TPI1 triose-phosphate isomerase YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR073W SNF11 component of SWI/SNF transcription activator complex YDR074W TPS2 alpha,alpha-trehalose-phosphate synthase, 102 KD subunit YDR081C PDC2 pyruvate decarboxylase regulatory protein YDR148C KGD2 2-oxoglutarate dehydrogenase complex E2 component YDR176W NGG1 general transcriptional adaptor or co-activator YDR178W SDH4 succinate dehydrogenase membrane anchor subunit for SDH2P YDR216W ADR1 zinc-finger transcription factor YDR245W MNN10 subunit of mannosyltransferase complex YDR248C YDR248C strong similarity to E.coli thermoresistant gluconokinase YDR261C EXG2 exo-beta-1,3-glucanase minor isoform YDR277C MTH1 repressor of hexose transport genes YDR307W YDR307W similarity to PMT1P, PMT2P, PMT3P and PMT5P YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR342C HXT7 high-affinity hexose transporter YDR343C HXT6 high-affinity hexose transporter YDR345C HXT3 low-affinity hexose transporter YDR368W YPR1 strong similarity to members of the aldo/keto reductase family YDR371W YDR371W similarity to chitinases YDR380W ARO10 similarity to PDC6P, THI3P and to pyruvate decarboxylases YDR384C YDR384C strong similarity to Y.lipolytica GPR1 gene YDR387C YDR387C similarity to ITR1P and ITR2P and E.coli araE YDR420W HKR1 Hansenula MrakII k9 killer toxin-resistance protein YDR422C SIP1 multicopy suppressor of SNF1 YDR443C SSN2 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDR477W SNF1 carbon catabolite derepressing ser/thr protein kinase YDR483W KRE2 alpha-1,2-mannosyltransferase YDR497C ITR1 myo-inositol permease, major YDR516C YDR516C strong similarity to glucokinase YDR536W STL1 member of the sugar permease family YEL002C WBP1 oligosaccharyl transferase beta subunit precursor YEL004W YEA4 strong similarity to K.lactis golgi uridine diphosphate-N-acetylglucosamine transporter YEL011W GLC3 1,4-glucan branching enzyme (glycogen branching enzyme) YEL020C YEL020C similarity to O.formigenes oxalyl-CoA decarboxylase YEL058W PCM1 phosphoacetylglucosamine mutase YEL069C HXT13 high-affinity hexose transporter YEL070W YEL070W strong similarity to E.coli D-mannonate oxidoreductase YER001W MNN1 alpha-1,3-mannosyltransferase YER003C PMI40 mannose-6-phosphate isomerase YER024W YAT2 carnitine O-acetyltransferase YER027C GAL83 glucose repression protein YER054C GIP2 GLC7P-interacting protein YER062C HOR2 DL-glycerol phosphatase YER065C ICL1 isocitrate lyase YER096W SHC1 sporulation specific protein YER120W SCS2 required for inositol metabolism YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER178W PDA1 pyruvate dehydrogenase (lipoamide) alpha chain precursor YFL011W HXT10 hexose transporter YFL014W HSP12 heat shock protein YFL040W YFL040W similarity to yeast glucose transport proteins YFL045C SEC53 phosphomannomutase YFL052W YFL052W strong similarity to Mal63p, YPR196w and MAL13P YFL053W DAK2 dihydroxyacetone kinase YFL056C AAD6 strong similarity to aryl-alcohol dehydrogenases YFL057C YFL057C strong similarity to aryl-alcohol dehydrogenases YFR015C GSY1 UDP glucose--starch glucosyltransferase, isoform 1 YFR053C HXK1 hexokinase I YGL022W STT3 oligosaccharyl transferase subunit YGL027C CWH41 ER glucosidase I YGL035C MIG1 transcriptional repressor YGL038C OCH1 alpha-1,6-mannosyltransferase YGL062W PYC1 pyruvate carboxylase 1 YGL065C ALG2 mannosyltransferase YGL104C YGL104C similarity to glucose transport proteins YGL115W SNF4 nuclear regulatory protein YGL134W PCL10 cyclin like protein interacting with PHO85P YGL156W AMS1 alpha-mannosidase YGL209W MIG2 C2H2 zinc-finger protein YGL226C-A OST5 subunit of N-oligosaccharyltransferase, zeta subunit YGL252C RTG2 retrograde regulation protein YGL253W HXK2 hexokinase II YGL256W ADH4 alcohol dehydrogenase IV YGL257C MNT2 alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides YGR032W GSC2 1,3-beta-D-glucan synthase subunit YGR043C YGR043C strong similarity to transaldolase YGR070W ROM1 GDP/GTP exchange protein for RHO1P YGR087C PDC6 pyruvate decarboxylase 3 YGR143W SKN1 glucan synthase subunit YGR166W KRE11 beta-glucan synthesis-associated protein YGR177C ATF2 alcohol O-acetyltransferase YGR192C TDH3 glyceraldehyde-3-phosphate dehydrogenase 3 YGR193C PDX1 pyruvate dehydrogenase complex protein X YGR194C XKS1 xylulokinase YGR199W PMT6 putative mannosyltransferase YGR227W DIE2 ITR1 expression promoting protein YGR229C SMI1 beta-1,3-glucan synthesis protein YGR240C PFK1 6-phosphofructokinase, alpha subunit YGR244C LSC2 succinate-CoA ligase beta subunit YGR254W ENO1 enolase I (2-phosphoglycerate dehydratase) YGR256W GND2 phosphogluconate dehydrogenase YGR282C BGL2 endo-beta-1,3-glucanase of the cell wall YGR287C YGR287C strong similarity to maltase YGR288W MAL13 maltose pathway regulatory protein YGR289C MAL11 general alpha-glucoside permease YGR292W MAL12 alpha-glucosidase of the MAL1 locus YHL012W YHL012W similarity to UDP Glucose pyrophosphorylase YHL025W SNF6 global transcription activator YHL032C GUT1 glycerol kinase YHR043C DOG2 2-deoxyglucose-6-phosphate phosphatase YHR044C DOG1 2-deoxyglucose-6-phosphate phosphatase YHR047C AAP1' alanine/arginine aminopeptidase YHR092C HXT4 moderate- to low-affinity glucose transporter YHR094C HXT1 low-affinity hexose transporter YHR096C HXT5 member of the hexose transporter family YHR101C BIG1 big cells phenotype YHR104W GRE3 aldose reductase YHR107C CDC12 septin YHR155W YHR155W strong similarity to SNF1P-interacting protein SIP3P YHR174W ENO2 enolase II (2-phosphoglycerate dehydratase) YHR183W GND1 6-phosphogluconate dehydrogenase YHR193C EGD2 alpha subunit of the nascent polypeptide-associated complex YHR204W HTM1 similarity to alpha-mannosidases YHR210C YHR210C strong similarity to UDP-glucose-4-epimerase YIL014W MNT3 alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL045W PIG2 Protein Interacting with GSY2P YIL053W RHR2 DL-glycerol phosphatase YIL085C KTR7 putative alpha-1,2-mannosyltransferase YIL099W SGA1 sporulation specific glucan 1,4-alpha-glucosidase YIL107C PFK26 6-phosphofructose-2-kinase, isozyme 1 YIL119C RPI1 negative regulator of ras-cAMP pathway YIL124W AYR1 1-Acyldihydroxyacetone-phosphate reductase YIL125W KGD1 2-oxoglutarate dehydrogenase complex E1 component YIL147C SLN1 two-component signal transducer YIL154C (IMP2) sugar utilization regulatory protein YIL155C GUT2 glycerol-3-phosphate dehydrogenase, mitochondrial YIL162W SUC2 invertase (sucrose hydrolyzing enzyme) YIL170W HXT12 strong similarity to sugar transport proteins YIL171W HXT12 strong similarity to sugar transport proteins YIL172C YIL172C identical to FSP2P and similarity to other alpha-glucosidases YIR019C MUC1 extracellular alpha-1,4-glucan glucosidase YIR031C DAL7 malate synthase 2 YIR036C YIR036C similarity to E.coli fabD YJL002C OST1 oligosaccharyltransferase, alpha subunit YJL045W YJL045W strong similarity to succinate dehydrogenase flavoprotein YJL052W TDH1 glyceraldehyde-3-phosphate dehydrogenase 1 YJL099W CHS6 chitin biosynthesis protein YJL121C RPE1 D-ribulose-5-phosphate 3-epimerase YJL128C PBS2 tyrosine protein kinase of the MAP kinase kinase family YJL137C GLG2 self-glucosylating initiator of glycogen synthesis YJL139C YUR1 mannosyltransferase YJL153C INO1 myo-inositol-1-phosphate synthase YJL155C FBP26 fructose-2,6-bisphosphatase YJL174W KRE9 cell wall synthesis protein YJL176C SWI3 transcription regulatory protein YJL186W MNN5 putative mannosyltransferase YJL214W HXT8 hexose transport protein YJL216C YJL216C strong similarity to Mal62p YJL218W YJL218W strong similarity to E.coli galactoside O-acetyltransferase YJL219W HXT9 hexose transport protein YJL221C FSP2 strong similarity to alpha-D-glucosidase YJR009C TDH2 glyceraldehyde-3-phosphate dehydrogenase 2 YJR075W HOC1 suppressor of PKC1 YJR076C CDC11 septin YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR095W SFC1 succinate-fumarate transporter YJR096W YJR096W similarity to Corynebacterium 2,5-diketo-D-gluconic acid reductase and aldehyde reductases YJR131W MNS1 alpha1,2-mannosidase YJR143C PMT4 dolichyl-phosphate-mannose--protein O-mannosyl transferase YJR153W PGU1 Endo-polygalacturonase YJR155W AAD10 strong similarity to aryl-alcohol dehydrogenase YJR158W HXT16 member of the hexose transporter family of the major facilitator superfamily [MFS] YJR159W SOR1 sorbitol dehydrogenase YJR160C YJR160C strong similarity to MAL31P YKL029C MAE1 malic enzyme YKL035W UGP1 UTP--glucose-1-phosphate uridylyltransferase YKL038W RGT1 regulator of glucose-induced genes YKL060C FBA1 fructose-bisphosphate aldolase YKL062W MSN4 transcriptional activator YKL085W MDH1 malate dehydrogenase precursor, mitochondrial YKL104C GFA1 glucosamine--fructose-6-phosphate transaminase YKL127W PGM1 phosphoglucomutase, minor isoform YKL148C SDH1 succinate dehydrogenase flavoprotein precursor YKL152C GPM1 phosphoglycerate mutase YKL217W JEN1 carboxylic acid transporter protein YKR027W YKR027W strong similarity to CHS6P YKR043C YKR043C weak similarity to phosphoglycerate mutase YKR061W KTR2 mannosyltransferase YKR096W YKR096W similarity to mitochondrial aldehyde dehydrogenase Ald1p YKR097W PCK1 phosphoenolpyruvate carboxykinase YLL016W SDC25 GDP/GTP exchange factor (GEF) YLL043W FPS1 glycerol channel protein YLR006C SSK1 two-component signal transducer YLR025W SNF7 class E Vps protein YLR044C PDC1 pyruvate decarboxylase, isozyme 1 YLR070C YLR070C strong similarity to sugar dehydrogenases YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR081W GAL2 galactose (and glucose) permease YLR113W HOG1 ser/thr protein kinase of MAP kinase (MAPK) family YLR131C ACE2 metallothionein expression activator YLR134W PDC5 pyruvate decarboxylase, isozyme 2 YLR150W STM1 specific affinity for guanine-rich quadruplex nucleic acids YLR153C ACS2 acetyl-coenzyme A synthetase YLR164W YLR164W strong similarity to SDH4P YLR174W IDP2 isocitrate dehydrogenase, cytosolic YLR258W GSY2 UDP-glucose--starch glucosyltransferase, isoform 2 YLR273C PIG1 putative type 1 phosphatase regulatory subunit YLR286C CTS1 endochitinase YLR300W EXG1 exo-beta-1,3-glucanase (I/II), major isoform YLR304C ACO1 aconitate hydratase YLR307W CDA1 sporulation-specific chitin deacetylase YLR308W CDA2 sporulation-specific chitin deacetylase YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR330W CHS5 chitin synthesis protein YLR342W FKS1 1,3-beta-D-glucan synthase, catalytic subunit YLR345W YLR345W similarity to PFK26P and other 6-phosphofructo-2-kinases YLR348C DIC1 dicarboxylate carrier protein YLR354C TAL1 transaldolase YLR371W ROM2 GDP/GTP exchange factor for RHO1P YLR377C FBP1 fructose-1,6-bisphosphatase YML019W OST6 N-oligosaccharyltransferase complex subunit YML048W GSF2 involved in glucose repression YML051W GAL80 negative regulator for expression of galactose-induced genes YML054C CYB2 lactate dehydrogenase cytochrome b2 YML070W DAK1 dihydroxyacetone kinase, induced in high salt YML086C ALO1 D-arabinono-1,4-lactone oxidase YML100W TSL1 alpha,alpha-trehalose-phosphate synthase, 123 KD subunit YMR011W HXT2 high-affinity hexose transporter YMR043W MCM1 transcription factor of the MADS box family YMR083W ADH3 alcohol dehydrogenase III YMR105C PGM2 phosphoglucomutase, major isoform YMR149W SWP1 oligosaccharyltransferase delta subunit YMR205C PFK2 6-phosphofructokinase, beta subunit YMR237W YMR237W similarity to CHS6 protein YMR261C TPS3 alpha,alpha-trehalose-phosphate synthase, 115 KD subunit YMR278W YMR278W similarity to phosphomannomutases YMR280C CAT8 transcription factor involved in gluconeogenesis YMR303C ADH2 alcohol dehydrogenase II YMR306W FKS3 similarity to 1,3-beta-glucan synthases YMR311C GLC8 regulatory subunit for protein ser/thr phosphatase GLC7P YMR318C YMR318C strong similarity to alcohol-dehydrogenase YMR323W YMR323W strong similarity to phosphopyruvate hydratases YNL025C SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YNL029C KTR5 putative mannosyltransferase YNL037C IDH1 isocitrate dehydrogenase (NAD+) subunit 1, mitochondrial YNL048W ALG11 required for asparagine-linked glycosylation YNL066W SUN4 strong similarity to YIL123w, UTH1P, NCA3P and C. wickerhamii beta-glucosidase protein YNL071W LAT1 dihydrolipoamide S-acetyltransferase YNL076W MKS1 pleiotropic regulatory factor YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL098C RAS2 GTP-binding protein YNL117W MLS1 malate synthase 1 YNL192W CHS1 chitin synthase I YNL199C GCR2 glycolytic genes transcriptional activator YNL201C YNL201C weak similarity to pleiotropic drug resistance control protein PDR6 YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL219C ALG9 mannosyltransferase YNL236W SIN4 global regulator protein YNL241C ZWF1 glucose-6-phosphate dehydrogenase YNL257C SIP3 SNF1P protein kinase interacting protein YNL274C YNL274C similarity to glycerate- and formate-dehydrogenases YNL283C WSC2 glucoamylase III (alpha-1,4-glucan-glucosidase) YNL318C HXT14 hexose transport protein YNL322C KRE1 cell wall protein YNL331C AAD14 strong similarity aryl-alcohol reductase YNR001C CIT1 citrate (si)-synthase, mitochondrial YNR002C FUN34 strong similarity to Y.lipolytica glyoxylate pathway regulator GPR1 YNR052C POP2 required for glucose derepression YNR059W MNT4 similarity to to alpha-1,3-mannosyltransferase YNR071C YNR071C strong similarity to UDP-glucose 4-epimerase GAL10P YNR072W HXT17 sugar transport protein YNR073C YNR073C strong similarity to E.coli D-mannonate oxidoreductase, identical to YEL070w YOL007C CSI2 involved in chitin synthesis YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL056W GPM3 phosphoglycerate mutase YOL059W GPD2 glycerol-3-phosphate dehydrogenase (NAD+), mitochondrial YOL067C RTG1 basic helix-loop-helix transcription factor that regulates CIT2 gene expression YOL086C ADH1 alcohol dehydrogenase I YOL103W ITR2 myo-inositol permease, minor YOL110W SHR5 RAS suppressor YOL116W MSN1 transcriptional activator YOL126C MDH2 malate dehydrogenase, cytoplasmic YOL136C PFK27 6-phosphofructose-2-kinase, isoenzyme 2 YOL156W HXT11 low affinity glucose transport protein YOL157C YOL157C strong similarity to alpha-glucosidases YOL165C AAD15 putative aryl alcohol dehydrogenase YOR002W ALG6 glucosyltransferase YOR047C STD1 dosage-dependent modulator of glucose repression YOR067C ALG8 glucosyltransferase YOR085W OST3 oligosaccharyltransferase gamma subunit YOR095C RKI1 D-ribose-5-phosphate ketol-isomerase YOR099W KTR1 mannosyltransferase involved in n-linked and o-linked glycosylation YOR101W RAS1 GTP-binding protein YOR103C OST2 oligosaccharyltransferase epsilon subunit YOR110W TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa YOR120W GCY1 galactose-induced protein of aldo/keto reductase family YOR125C CAT5 involved in coenzyme Q (ubiquinone) biosynthesis YOR126C IAH1 isoamyl acetate hydrolytic enzyme YOR136W IDH2 isocitrate dehydrogenase (NAD+) subunit 2, mitochondrial YOR142W LSC1 succinate-CoA ligase alpha subunit YOR178C GAC1 ser/thr phosphoprotein phosphatase 1, regulatory chain YOR190W SPR1 exo-1,3-beta-glucanase precursor YOR283W YOR283W weak similarity to phosphoglycerate mutases YOR290C SNF2 component of SWI/SNF global transcription activator complex YOR299W BUD7 involved in bud-site selection YOR321W PMT3 mannosyltransferase YOR336W KRE5 killer toxin-resistance protein YOR344C TYE7 basic helix-loop-helix transcription factor YOR347C PYK2 pyruvate kinase, glucose-repressed isoform YOR377W ATF1 alcohol acetyltransferase YOR393W ERR1 enolase related protein YPL002C SNF8 involved in glucose derepression YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL017C YPL017C strong similarity to LPD1P and other dihydrolipoamide dehydrogenases YPL026C SKS1 suppressor kinase of SNF3 YPL031C PHO85 cyclin-dependent protein kinase YPL037C EGD1 GAL4 DNA-binding enhancer protein YPL042C SSN3 cyclin-dependent CTD kinase YPL050C MNN9 required for complex N-glycosylation YPL053C KTR6 mannosylphosphate transferase YPL075W GCR1 transcriptional activator YPL088W YPL088W similarity to aryl-alcohol dehydrogenases YPL113C YPL113C similarity to glycerate dehydrogenases YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL161C BEM4 bud emergence protein YPL175W SPT14 N-acetylglucosaminyltransferase YPL219W PCL8 cyclin like protein interacting with PHO85P YPL227C ALG5 dolichol-P-glucose synthetase YPL248C GAL4 transcription factor YPL281C ERR2 enolase related protein YPR001W CIT3 citrate (si)-synthase, mitochondrial YPR006C ICL2 non-functional isocitrate lyase YPR021C YPR021C similarity to human citrate transporter protein YPR026W ATH1 acid trehalase, vacuolar YPR074C TKL1 transketolase 1 YPR159W KRE6 glucan synthase subunit YPR160W GPH1 glycogen phosphorylase YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins YPR183W DPM1 dolichyl-phosphate beta-D-mannosyltransferase YPR184W GDB1 similarity to human 4-alpha-glucanotransferase (EC 2.4.1.25)/amylo-1,6-glucosidase (EC 3.2.1.33) C-compound and carbohydrate utilization (261 ORFs) 01.05.01 261 YAL023C PMT2 mannosyltransferase YAL038W CDC19 pyruvate kinase YAL054C ACS1 acetyl-CoA synthetase YAL060W BDH1 stereospecific (2R, 3R)-2,3-butanediol dehydrogenase YAL061W FUN50 similarity to alcohol/sorbitol dehydrogenase YBL001C ECM15 involved in cell wall biogenesis and architecture YBL082C RHK1 mannosyltransferase YBR001C NTH2 alpha,alpha-trehalase YBR018C GAL7 UDP-glucose--hexose-1-phosphate uridylyltransferase YBR019C GAL10 UDP-glucose 4-epimerase YBR020W GAL1 galactokinase YBR023C CHS3 chitin synthase III YBR030W YBR030W weak similarity to regulatory protein MSR1P YBR038W CHS2 chitin synthase II YBR056W YBR056W similarity to glucan 1,3-beta-glucosidase YBR084W MIS1 C1-tetrahydrofolate synthase precursor, mitochondrial YBR110W ALG1 beta-mannosyltransferase YBR117C TKL2 transketolase 2 YBR126C TPS1 alpha,alpha-trehalose-phosphate synthase, 56 KD subunit YBR145W ADH5 alcohol dehydrogenase V YBR149W ARA1 D-arabinose dehydrogenase, large subunit YBR196C PGI1 glucose-6-phosphate isomerase YBR199W KTR4 alpha-1,2-mannosyltransferase YBR205W KTR3 alpha-1,2-mannosyltransferase YBR218C PYC2 pyruvate carboxylase 2 YBR221C PDB1 pyruvate dehydrogenase (lipoamide) beta chain precursor YBR229C ROT2 glucosidase II, catalytic subunit YBR243C ALG7 UDP-N-acetylglucosamine-1-phosphate transferase YBR299W MAL32 alpha-glucosidase YCL040W GLK1 aldohexose specific glucokinase YCR005C CIT2 citrate (si)-synthase, peroxisomal YCR012W PGK1 phosphoglycerate kinase YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR036W RBK1 ribokinase YCR105W YCR105W strong similarity to alcohol dehydrogenases YCR107W AAD3 strong similarity aryl-alcohol reductases of P. chrysosporium YDL013W HEX3 hexose metabolism-related protein YDL021W GPM2 phosphoglycerate mutase YDL022W GPD1 glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic YDL037C YDL037C strong similarity to glucan 1,4-alpha-glucosidase YDL049C KNH1 functional homolog of KRE9 YDL055C PSA1 mannose-1-phosphate guanyltransferase YDL066W IDP1 isocitrate dehydrogenase (NADP+), mitochondrial YDL078C MDH3 malate dehydrogenase, peroxisomal YDL093W PMT5 O-mannosyltransferase similarity to PMT1P-PMT4P YDL095W PMT1 mannosyltransferase YDL124W YDL124W similarity to aldose reductases YDL131W LYS21 homocitrate synthase YDL168W SFA1 long-chain alcohol dehydrogenase YDL174C DLD1 D-lactate ferricytochrome C oxidoreductase (D-LCR) YDL182W LYS20 homocitrate synthase YDL232W OST4 oligosaccharyltransferase subunit YDL243C AAD4 strong similarity to aryl-alcohol dehydrogenase YDL246C YDL246C strong similarity to SOR1P YDR001C NTH1 neutral trehalase (alpha,alpha-trehalase) YDR050C TPI1 triose-phosphate isomerase YDR074W TPS2 alpha,alpha-trehalose-phosphate synthase, 102 KD subunit YDR081C PDC2 pyruvate decarboxylase regulatory protein YDR148C KGD2 2-oxoglutarate dehydrogenase complex E2 component YDR178W SDH4 succinate dehydrogenase membrane anchor subunit for SDH2P YDR245W MNN10 subunit of mannosyltransferase complex YDR248C YDR248C strong similarity to E.coli thermoresistant gluconokinase YDR261C EXG2 exo-beta-1,3-glucanase minor isoform YDR307W YDR307W similarity to PMT1P, PMT2P, PMT3P and PMT5P YDR368W YPR1 strong similarity to members of the aldo/keto reductase family YDR371W YDR371W similarity to chitinases YDR380W ARO10 similarity to PDC6P, THI3P and to pyruvate decarboxylases YDR384C YDR384C strong similarity to Y.lipolytica GPR1 gene YDR483W KRE2 alpha-1,2-mannosyltransferase YDR516C YDR516C strong similarity to glucokinase YEL002C WBP1 oligosaccharyl transferase beta subunit precursor YEL011W GLC3 1,4-glucan branching enzyme (glycogen branching enzyme) YEL020C YEL020C similarity to O.formigenes oxalyl-CoA decarboxylase YEL058W PCM1 phosphoacetylglucosamine mutase YEL070W YEL070W strong similarity to E.coli D-mannonate oxidoreductase YER001W MNN1 alpha-1,3-mannosyltransferase YER003C PMI40 mannose-6-phosphate isomerase YER062C HOR2 DL-glycerol phosphatase YER065C ICL1 isocitrate lyase YER096W SHC1 sporulation specific protein YER178W PDA1 pyruvate dehydrogenase (lipoamide) alpha chain precursor YFL014W HSP12 heat shock protein YFL045C SEC53 phosphomannomutase YFL053W DAK2 dihydroxyacetone kinase YFL056C AAD6 strong similarity to aryl-alcohol dehydrogenases YFL057C YFL057C strong similarity to aryl-alcohol dehydrogenases YFR015C GSY1 UDP glucose--starch glucosyltransferase, isoform 1 YFR053C HXK1 hexokinase I YGL022W STT3 oligosaccharyl transferase subunit YGL027C CWH41 ER glucosidase I YGL038C OCH1 alpha-1,6-mannosyltransferase YGL062W PYC1 pyruvate carboxylase 1 YGL065C ALG2 mannosyltransferase YGL156W AMS1 alpha-mannosidase YGL226C-A OST5 subunit of N-oligosaccharyltransferase, zeta subunit YGL253W HXK2 hexokinase II YGL256W ADH4 alcohol dehydrogenase IV YGL257C MNT2 alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides YGR032W GSC2 1,3-beta-D-glucan synthase subunit YGR043C YGR043C strong similarity to transaldolase YGR087C PDC6 pyruvate decarboxylase 3 YGR143W SKN1 glucan synthase subunit YGR177C ATF2 alcohol O-acetyltransferase YGR192C TDH3 glyceraldehyde-3-phosphate dehydrogenase 3 YGR193C PDX1 pyruvate dehydrogenase complex protein X YGR194C XKS1 xylulokinase YGR199W PMT6 putative mannosyltransferase YGR240C PFK1 6-phosphofructokinase, alpha subunit YGR244C LSC2 succinate-CoA ligase beta subunit YGR254W ENO1 enolase I (2-phosphoglycerate dehydratase) YGR256W GND2 phosphogluconate dehydrogenase YGR282C BGL2 endo-beta-1,3-glucanase of the cell wall YGR287C YGR287C strong similarity to maltase YGR292W MAL12 alpha-glucosidase of the MAL1 locus YHL012W YHL012W similarity to UDP Glucose pyrophosphorylase YHL032C GUT1 glycerol kinase YHR043C DOG2 2-deoxyglucose-6-phosphate phosphatase YHR044C DOG1 2-deoxyglucose-6-phosphate phosphatase YHR101C BIG1 big cells phenotype YHR104W GRE3 aldose reductase YHR174W ENO2 enolase II (2-phosphoglycerate dehydratase) YHR183W GND1 6-phosphogluconate dehydrogenase YHR204W HTM1 similarity to alpha-mannosidases YHR210C YHR210C strong similarity to UDP-glucose-4-epimerase YIL014W MNT3 alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides YIL045W PIG2 Protein Interacting with GSY2P YIL053W RHR2 DL-glycerol phosphatase YIL085C KTR7 putative alpha-1,2-mannosyltransferase YIL099W SGA1 sporulation specific glucan 1,4-alpha-glucosidase YIL107C PFK26 6-phosphofructose-2-kinase, isozyme 1 YIL124W AYR1 1-Acyldihydroxyacetone-phosphate reductase YIL125W KGD1 2-oxoglutarate dehydrogenase complex E1 component YIL155C GUT2 glycerol-3-phosphate dehydrogenase, mitochondrial YIL162W SUC2 invertase (sucrose hydrolyzing enzyme) YIL172C YIL172C identical to FSP2P and similarity to other alpha-glucosidases YIR019C MUC1 extracellular alpha-1,4-glucan glucosidase YIR031C DAL7 malate synthase 2 YIR036C YIR036C similarity to E.coli fabD YJL002C OST1 oligosaccharyltransferase, alpha subunit YJL045W YJL045W strong similarity to succinate dehydrogenase flavoprotein YJL052W TDH1 glyceraldehyde-3-phosphate dehydrogenase 1 YJL099W CHS6 chitin biosynthesis protein YJL121C RPE1 D-ribulose-5-phosphate 3-epimerase YJL137C GLG2 self-glucosylating initiator of glycogen synthesis YJL139C YUR1 mannosyltransferase YJL153C INO1 myo-inositol-1-phosphate synthase YJL155C FBP26 fructose-2,6-bisphosphatase YJL174W KRE9 cell wall synthesis protein YJL186W MNN5 putative mannosyltransferase YJL216C YJL216C strong similarity to Mal62p YJL218W YJL218W strong similarity to E.coli galactoside O-acetyltransferase YJL221C FSP2 strong similarity to alpha-D-glucosidase YJR009C TDH2 glyceraldehyde-3-phosphate dehydrogenase 2 YJR075W HOC1 suppressor of PKC1 YJR096W YJR096W similarity to Corynebacterium 2,5-diketo-D-gluconic acid reductase and aldehyde reductases YJR131W MNS1 alpha1,2-mannosidase YJR143C PMT4 dolichyl-phosphate-mannose--protein O-mannosyl transferase YJR153W PGU1 Endo-polygalacturonase YJR155W AAD10 strong similarity to aryl-alcohol dehydrogenase YJR159W SOR1 sorbitol dehydrogenase YKL029C MAE1 malic enzyme YKL035W UGP1 UTP--glucose-1-phosphate uridylyltransferase YKL060C FBA1 fructose-bisphosphate aldolase YKL085W MDH1 malate dehydrogenase precursor, mitochondrial YKL104C GFA1 glucosamine--fructose-6-phosphate transaminase YKL127W PGM1 phosphoglucomutase, minor isoform YKL148C SDH1 succinate dehydrogenase flavoprotein precursor YKL152C GPM1 phosphoglycerate mutase YKR027W YKR027W strong similarity to CHS6P YKR043C YKR043C weak similarity to phosphoglycerate mutase YKR061W KTR2 mannosyltransferase YKR096W YKR096W similarity to mitochondrial aldehyde dehydrogenase Ald1p YKR097W PCK1 phosphoenolpyruvate carboxykinase YLR044C PDC1 pyruvate decarboxylase, isozyme 1 YLR070C YLR070C strong similarity to sugar dehydrogenases YLR134W PDC5 pyruvate decarboxylase, isozyme 2 YLR153C ACS2 acetyl-coenzyme A synthetase YLR164W YLR164W strong similarity to SDH4P YLR174W IDP2 isocitrate dehydrogenase, cytosolic YLR258W GSY2 UDP-glucose--starch glucosyltransferase, isoform 2 YLR286C CTS1 endochitinase YLR300W EXG1 exo-beta-1,3-glucanase (I/II), major isoform YLR304C ACO1 aconitate hydratase YLR307W CDA1 sporulation-specific chitin deacetylase YLR308W CDA2 sporulation-specific chitin deacetylase YLR342W FKS1 1,3-beta-D-glucan synthase, catalytic subunit YLR354C TAL1 transaldolase YLR377C FBP1 fructose-1,6-bisphosphatase YML019W OST6 N-oligosaccharyltransferase complex subunit YML054C CYB2 lactate dehydrogenase cytochrome b2 YML070W DAK1 dihydroxyacetone kinase, induced in high salt YML086C ALO1 D-arabinono-1,4-lactone oxidase YML100W TSL1 alpha,alpha-trehalose-phosphate synthase, 123 KD subunit YMR083W ADH3 alcohol dehydrogenase III YMR105C PGM2 phosphoglucomutase, major isoform YMR149W SWP1 oligosaccharyltransferase delta subunit YMR205C PFK2 6-phosphofructokinase, beta subunit YMR237W YMR237W similarity to CHS6 protein YMR261C TPS3 alpha,alpha-trehalose-phosphate synthase, 115 KD subunit YMR278W YMR278W similarity to phosphomannomutases YMR303C ADH2 alcohol dehydrogenase II YMR306W FKS3 similarity to 1,3-beta-glucan synthases YMR318C YMR318C strong similarity to alcohol-dehydrogenase YMR323W YMR323W strong similarity to phosphopyruvate hydratases YNL029C KTR5 putative mannosyltransferase YNL037C IDH1 isocitrate dehydrogenase (NAD+) subunit 1, mitochondrial YNL048W ALG11 required for asparagine-linked glycosylation YNL071W LAT1 dihydrolipoamide S-acetyltransferase YNL117W MLS1 malate synthase 1 YNL192W CHS1 chitin synthase I YNL219C ALG9 mannosyltransferase YNL241C ZWF1 glucose-6-phosphate dehydrogenase YNL274C YNL274C similarity to glycerate- and formate-dehydrogenases YNL283C WSC2 glucoamylase III (alpha-1,4-glucan-glucosidase) YNL322C KRE1 cell wall protein YNL331C AAD14 strong similarity aryl-alcohol reductase YNR001C CIT1 citrate (si)-synthase, mitochondrial YNR059W MNT4 similarity to to alpha-1,3-mannosyltransferase YNR071C YNR071C strong similarity to UDP-glucose 4-epimerase GAL10P YNR073C YNR073C strong similarity to E.coli D-mannonate oxidoreductase, identical to YEL070w YOL056W GPM3 phosphoglycerate mutase YOL059W GPD2 glycerol-3-phosphate dehydrogenase (NAD+), mitochondrial YOL086C ADH1 alcohol dehydrogenase I YOL126C MDH2 malate dehydrogenase, cytoplasmic YOL136C PFK27 6-phosphofructose-2-kinase, isoenzyme 2 YOL157C YOL157C strong similarity to alpha-glucosidases YOL165C AAD15 putative aryl alcohol dehydrogenase YOR002W ALG6 glucosyltransferase YOR067C ALG8 glucosyltransferase YOR085W OST3 oligosaccharyltransferase gamma subunit YOR095C RKI1 D-ribose-5-phosphate ketol-isomerase YOR099W KTR1 mannosyltransferase involved in n-linked and o-linked glycosylation YOR103C OST2 oligosaccharyltransferase epsilon subunit YOR120W GCY1 galactose-induced protein of aldo/keto reductase family YOR126C IAH1 isoamyl acetate hydrolytic enzyme YOR136W IDH2 isocitrate dehydrogenase (NAD+) subunit 2, mitochondrial YOR142W LSC1 succinate-CoA ligase alpha subunit YOR190W SPR1 exo-1,3-beta-glucanase precursor YOR283W YOR283W weak similarity to phosphoglycerate mutases YOR299W BUD7 involved in bud-site selection YOR321W PMT3 mannosyltransferase YOR336W KRE5 killer toxin-resistance protein YOR347C PYK2 pyruvate kinase, glucose-repressed isoform YOR377W ATF1 alcohol acetyltransferase YOR393W ERR1 enolase related protein YPL017C YPL017C strong similarity to LPD1P and other dihydrolipoamide dehydrogenases YPL050C MNN9 required for complex N-glycosylation YPL053C KTR6 mannosylphosphate transferase YPL088W YPL088W similarity to aryl-alcohol dehydrogenases YPL113C YPL113C similarity to glycerate dehydrogenases YPL175W SPT14 N-acetylglucosaminyltransferase YPL227C ALG5 dolichol-P-glucose synthetase YPL281C ERR2 enolase related protein YPR001W CIT3 citrate (si)-synthase, mitochondrial YPR006C ICL2 non-functional isocitrate lyase YPR026W ATH1 acid trehalase, vacuolar YPR074C TKL1 transketolase 1 YPR159W KRE6 glucan synthase subunit YPR160W GPH1 glycogen phosphorylase YPR183W DPM1 dolichyl-phosphate beta-D-mannosyltransferase YPR184W GDB1 similarity to human 4-alpha-glucanotransferase (EC 2.4.1.25)/amylo-1,6-glucosidase (EC 3.2.1.33) C-compound, carbohydrate anabolism (1 ORF) 01.05.01.03 1 YJL186W MNN5 putative mannosyltransferase polysaccharide biosynthesis (1 ORF) 01.05.01.03.02 1 YJL186W MNN5 putative mannosyltransferase regulation of C-compound and carbohydrate utilization (120 ORFs) 01.05.04 120 YAL021C CCR4 transcriptional regulator YBL061C SKT5 protoplast regeneration and killer toxin resistance protein YBL103C RTG3 bHLH/zip transcription factor that regulates CIT2 gene expression YBR050C REG2 regulatory subunit of type I protein phosphatase YBR126C TPS1 alpha,alpha-trehalose-phosphate synthase, 56 KD subunit YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR289W SNF5 component of SWI/SNF transcription activator complex YBR297W MAL33 maltose fermentation regulatory protein YCR002C CDC10 cell division control protein YCR010C ADY2 strong similarity to Y.lipolytica GPR1 protein and FUN34P YCR028C FEN2 high affinity H+/pantothenate symporter YCR081W SRB8 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDL006W PTC1 protein serine/threonine phosphatase 2c YDL132W CDC53 controls G1/S transition YDL134C PPH21 protein ser/thr phosphatase PP2A-1 YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL203C YDL203C similarity to SKT5P YDR009W GAL3 galactokinase YDR028C REG1 regulatory subunit for protein phosphatase GLC7P YDR043C NRG1 transcriptional repressor for glucose repression of STA1 gene expression YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR073W SNF11 component of SWI/SNF transcription activator complex YDR176W NGG1 general transcriptional adaptor or co-activator YDR216W ADR1 zinc-finger transcription factor YDR277C MTH1 repressor of hexose transport genes YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR420W HKR1 Hansenula MrakII k9 killer toxin-resistance protein YDR422C SIP1 multicopy suppressor of SNF1 YDR443C SSN2 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDR477W SNF1 carbon catabolite derepressing ser/thr protein kinase YER027C GAL83 glucose repression protein YER054C GIP2 GLC7P-interacting protein YER120W SCS2 required for inositol metabolism YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YFL052W YFL052W strong similarity to Mal63p, YPR196w and MAL13P YGL035C MIG1 transcriptional repressor YGL115W SNF4 nuclear regulatory protein YGL134W PCL10 cyclin like protein interacting with PHO85P YGL209W MIG2 C2H2 zinc-finger protein YGL252C RTG2 retrograde regulation protein YGL253W HXK2 hexokinase II YGR070W ROM1 GDP/GTP exchange protein for RHO1P YGR166W KRE11 beta-glucan synthesis-associated protein YGR227W DIE2 ITR1 expression promoting protein YGR229C SMI1 beta-1,3-glucan synthesis protein YGR240C PFK1 6-phosphofructokinase, alpha subunit YGR288W MAL13 maltose pathway regulatory protein YHL025W SNF6 global transcription activator YHR047C AAP1' alanine/arginine aminopeptidase YHR107C CDC12 septin YHR155W YHR155W strong similarity to SNF1P-interacting protein SIP3P YHR193C EGD2 alpha subunit of the nascent polypeptide-associated complex YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL107C PFK26 6-phosphofructose-2-kinase, isozyme 1 YIL119C RPI1 negative regulator of ras-cAMP pathway YIL147C SLN1 two-component signal transducer YIL154C (IMP2) sugar utilization regulatory protein YJL128C PBS2 tyrosine protein kinase of the MAP kinase kinase family YJL155C FBP26 fructose-2,6-bisphosphatase YJL176C SWI3 transcription regulatory protein YJR076C CDC11 septin YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR095W SFC1 succinate-fumarate transporter YKL038W RGT1 regulator of glucose-induced genes YKL062W MSN4 transcriptional activator YLL016W SDC25 GDP/GTP exchange factor (GEF) YLR006C SSK1 two-component signal transducer YLR025W SNF7 class E Vps protein YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR113W HOG1 ser/thr protein kinase of MAP kinase (MAPK) family YLR131C ACE2 metallothionein expression activator YLR150W STM1 specific affinity for guanine-rich quadruplex nucleic acids YLR258W GSY2 UDP-glucose--starch glucosyltransferase, isoform 2 YLR273C PIG1 putative type 1 phosphatase regulatory subunit YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR330W CHS5 chitin synthesis protein YLR345W YLR345W similarity to PFK26P and other 6-phosphofructo-2-kinases YLR371W ROM2 GDP/GTP exchange factor for RHO1P YML048W GSF2 involved in glucose repression YML051W GAL80 negative regulator for expression of galactose-induced genes YMR043W MCM1 transcription factor of the MADS box family YMR205C PFK2 6-phosphofructokinase, beta subunit YMR280C CAT8 transcription factor involved in gluconeogenesis YMR311C GLC8 regulatory subunit for protein ser/thr phosphatase GLC7P YNL025C SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YNL076W MKS1 pleiotropic regulatory factor YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL098C RAS2 GTP-binding protein YNL199C GCR2 glycolytic genes transcriptional activator YNL201C YNL201C weak similarity to pleiotropic drug resistance control protein PDR6 YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL236W SIN4 global regulator protein YNL257C SIP3 SNF1P protein kinase interacting protein YNR002C FUN34 strong similarity to Y.lipolytica glyoxylate pathway regulator GPR1 YNR052C POP2 required for glucose derepression YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL067C RTG1 basic helix-loop-helix transcription factor that regulates CIT2 gene expression YOL110W SHR5 RAS suppressor YOL116W MSN1 transcriptional activator YOL136C PFK27 6-phosphofructose-2-kinase, isoenzyme 2 YOR047C STD1 dosage-dependent modulator of glucose repression YOR101W RAS1 GTP-binding protein YOR110W TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa YOR125C CAT5 involved in coenzyme Q (ubiquinone) biosynthesis YOR178C GAC1 ser/thr phosphoprotein phosphatase 1, regulatory chain YOR290C SNF2 component of SWI/SNF global transcription activator complex YOR344C TYE7 basic helix-loop-helix transcription factor YPL002C SNF8 involved in glucose derepression YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL026C SKS1 suppressor kinase of SNF3 YPL031C PHO85 cyclin-dependent protein kinase YPL037C EGD1 GAL4 DNA-binding enhancer protein YPL042C SSN3 cyclin-dependent CTD kinase YPL075W GCR1 transcriptional activator YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL161C BEM4 bud emergence protein YPL219W PCL8 cyclin like protein interacting with PHO85P YPL248C GAL4 transcription factor YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins C-compound, carbohydrate transport (42 ORFs) 01.05.07 42 YBR241C YBR241C similarity to glucose transport proteins YBR291C CTP1 citrate transport protein, mitochondrial (MCF) YBR298C MAL31 maltose permease YCL040W GLK1 aldohexose specific glucokinase YDL138W RGT2 suppressor of SNF3 mutant YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL199C YDL199C similarity to sugar transporter proteins YDL245C HXT15 strong similarity to HXT17P and HXT7P YDL247W YDL247W strong similarity to sugar transport proteins YDR342C HXT7 high-affinity hexose transporter YDR343C HXT6 high-affinity hexose transporter YDR345C HXT3 low-affinity hexose transporter YDR387C YDR387C similarity to ITR1P and ITR2P and E.coli araE YDR497C ITR1 myo-inositol permease, major YDR536W STL1 member of the sugar permease family YEL004W YEA4 strong similarity to K.lactis golgi uridine diphosphate-N-acetylglucosamine transporter YEL069C HXT13 high-affinity hexose transporter YER024W YAT2 carnitine O-acetyltransferase YFL011W HXT10 hexose transporter YFL040W YFL040W similarity to yeast glucose transport proteins YGL104C YGL104C similarity to glucose transport proteins YGR289C MAL11 general alpha-glucoside permease YHR092C HXT4 moderate- to low-affinity glucose transporter YHR094C HXT1 low-affinity hexose transporter YHR096C HXT5 member of the hexose transporter family YIL170W HXT12 strong similarity to sugar transport proteins YIL171W HXT12 strong similarity to sugar transport proteins YJL214W HXT8 hexose transport protein YJL219W HXT9 hexose transport protein YJR095W SFC1 succinate-fumarate transporter YJR158W HXT16 member of the hexose transporter family of the major facilitator superfamily [MFS] YJR160C YJR160C strong similarity to MAL31P YKL217W JEN1 carboxylic acid transporter protein YLL043W FPS1 glycerol channel protein YLR081W GAL2 galactose (and glucose) permease YLR348C DIC1 dicarboxylate carrier protein YMR011W HXT2 high-affinity hexose transporter YNL318C HXT14 hexose transport protein YNR072W HXT17 sugar transport protein YOL103W ITR2 myo-inositol permease, minor YOL156W HXT11 low affinity glucose transport protein YPR021C YPR021C similarity to human citrate transporter protein other C-compound, carbohydrate metabolism activities (2 ORFs) 01.05.99 2 YBL086C YBL086C weak similarity to S. pombe hypothetical protein YOL007C CSI2 involved in chitin synthesis lipid, fatty-acid and isoprenoid metabolism (213 ORFs) 01.06 213 YAL013W DEP1 regulator of phospholipid metabolism YAL051W OAF1 peroxisome proliferating transcription factor YAR035W YAT1 carnitine acetyltransferase, mitochondrial YAR042W SWH1 similarity to mammalian oxysterol-binding proteins YAR044W OSH1 similarity to human oxysterol binding protein (OSBP) YBL015W ACH1 acetyl-CoA hydrolase YBL088C TEL1 telomere length control protein YBR003W COQ1 hexaprenyl pyrophosphate synthetase precursor YBR029C CDS1 CDP-diacylglycerol synthase YBR036C CSG2 calcium dependent regulatory protein YBR041W FAT1 very long-chain fatty acyl-CoA synthetase YBR042C CST26 weak similarity to 1-acyl-sn-glycerol-3-phosphate acyltransferase from Brassica napus YBR058C-A TSC3 required for optimal serine palmitoyltransferase activity YBR067C TIP1 esterase YBR159W YBR159W similarity to human 17-beta-hydroxysteroid dehydrogenase YBR183W YPC1 Alkaline Ceramidase YBR204C YBR204C weak similarity to peroxisomal serine-active lipase YBR222C FAT2 AMP-binding protein, peroxisomal YBR263W SHM1 serine hydroxymethyltransferase precursor, mitochondrial YBR265W TSC10 3-ketosphinganine reductase YCL004W PGS1 phosphatidylglycerophosphate synthase YCL026C-A FRM2 involved in fatty acid regulation YCL043C PDI1 protein disulfide-isomerase precursor YCR028C FEN2 high affinity H+/pantothenate symporter YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR048W ARE1 acyl-CoA sterol acyltransferase YCR098C GIT1 glycerophosphoinositol transporter YDL015C TSC13 required for elongation of the very long chain fatty acid (VLCFA) moiety of sphingolipids YDL019C OSH2 similarity to SWH1P YDL040C NAT1 protein N-acetyltransferase subunit YDL052C SLC1 fatty acyltransferase YDL078C MDH3 malate dehydrogenase, peroxisomal YDL090C RAM1 protein farnesyltransferase, beta subunit YDL109C YDL109C strong similarity to hypothetical protein YGL144c YDL142C CRD1 cardiolipin synthase YDR011W SNQ2 multidrug resistance protein YDR058C TGL2 triacylglycerol lipase YDR062W LCB2 serine C-palmitoyltransferase subunit YDR072C IPT1 mannosyl diphosphorylinositol ceramide synthase YDR123C INO2 basic helix-loop-helix (BHLH) transcription factor YDR147W EKI1 ethanolamine kinase YDR207C UME6 negative transcriptional regulator YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR213W UPC2 regulatory protein involved in control of sterol uptake YDR284C DPP1 diacylglycerol pyrophosphate phosphatase YDR287W YDR287W similarity to inositolmonophosphatases YDR294C DPL1 dihydrosphingosine phosphate lyase YDR297W SUR2 required for the hydroxylation of C-4 of the sphingoid moiety of ceramide YDR302W GPI11 GPI11 - protein involved in glycosylphosphatidylinositol (GPI) biosynthesis YDR313C PIB1 phosphatidylinositol(3)-phosphate binding protein YDR331W GPI8 essential for GPI anchor attachment YDR376W ARH1 mitochondrial protein with similarity to human adrenodoxin reductase and ferredoxin-NADP+ reductase YDR410C STE14 farnesyl cysteine carboxyl-methyltransferase YDR444W YDR444W similarity to hypothetical protein YGL144c and YDL109c YDR452W PHM5 similarity to human sphingomyelin phosphodiesterase (PIR:S06957) YDR497C ITR1 myo-inositol permease, major YDR503C LPP1 lipid phosphate phosphatase YER015W FAA2 long-chain-fatty-acid--CoA ligase YER019W ISC1 weak similarity to human and mouse neutral sphingomyelinase YER024W YAT2 carnitine O-acetyltransferase YER026C CHO1 CDP-diacylglycerol serine O-phosphatidyltransferase YER044C ERG28 involved in synthesis of ergosterol YER061C CEM1 beta-keto-acyl-ACP synthase, mitochondrial YFL014W HSP12 heat shock protein YFL031W HAC1 transcription factor YFR019W FAB1 phosphatidylinositol 3-phosphate 5-kinase YGL001C ERG26 C-3 sterol dehydrogenase (C-4 decarboxylase) YGL012W ERG4 sterol C-24 reductase YGL055W OLE1 stearoyl-CoA desaturase YGL126W SCS3 inositol phospholipid synthesis protein YGL142C GPI10 required for Glycosyl Phosphatdyl Inositol synthesis YGL144C YGL144C strong similarity to hypothetical protein YDL109c YGL155W CDC43 geranylgeranyltransferase beta subunit YGL162W SUT1 hypoxic protein involved in sterol uptake YGL205W POX1 acyl-CoA oxidase YGR007W MUQ1 choline phosphate cytidylyltransferase YGR037C ACB1 acyl-coenzyme-A-binding protein (diazepam binding inhibitor) YGR060W ERG25 C-4 sterol methyl oxidase YGR157W CHO2 phosphatidylethanolamine N-methyltransferase YGR170W PSD2 phosphatidylserine decarboxylase 2 YGR175C ERG1 squalene monooxygenase YGR202C PCT1 cholinephosphate cytidylyltransferase YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YHL003C LAG1 longevity-assurance protein YHL020C OPI1 negative regulator of phospholipid biosynthesis pathway YHR001W OSH7 similarity to KES1P YHR007C ERG11 cytochrome P450 lanosterol 14a-demethylase YHR013C ARD1 protein N-acetyltransferase subunit YHR042W NCP1 NADPH-cytochrome P450 reductase YHR046C YHR046C similarity to inositolmonophosphatases YHR072W ERG7 lanosterol synthase YHR073W OSH3 similarity to OSH1P, YDL019c and mammalian oxysterol-binding protei YHR079C IRE1 protein kinase YHR123W EPT1 sn-1,2-diacylglycerol ethanolamine- and cholinephosphotransferase YHR190W ERG9 farnesyl-diphosphate farnesyltransferase YIL002C INP51 phosphatidylinositol phosphate 5-phosphatase YIL009W FAA3 acyl CoA synthase YIL160C POT1 acetyl-CoA C-acyltransferase, peroxisomal YIR035C YIR035C similarity to human corticosteroid 11-beta-dehydrogenase YJL031C BET4 geranylgeranyl transferase, alpha chain YJL068C YJL068C strong similarity to human esterase D YJL132W YJL132W weak similarity to human phospholipase D YJL134W LCB3 sphingoid base-phosphate phosphatase YJL145W YJL145W weak similarity to T.pacificus retinal-binding protein YJL167W ERG20 farnesyl-pyrophosphate synthetase YJL196C ELO1 fatty acid elongation protein YJR019C TES1 thioesterase, peroxisomal YJR066W TOR1 phosphatidylinositol 3-kinase YJR073C OPI3 methylene-fatty-acyl-phospholipid synthase YJR107W YJR107W weak similarity to acylglycerol lipase YKL004W AUR1 aureobasidin-resistance protein YKL019W RAM2 protein farnesyltransferase, alpha subunit YKL055C OAR1 putative 3-oxoacyl-(acyl carrier protein) reductase YKL140W TGL1 triacylglycerol lipase YKL174C YKL174C similarity to choline transport protein HNM1P YKL182W FAS1 fatty-acyl-CoA synthase, beta chain YKL188C PXA2 ABC transporter, peroxisomal YKL192C ACP1 mitochonrial acyl-carrier protein YKL203C TOR2 phosphatidylinositol 3-kinase YKL213C DOA1 involved in ubiquitin-dependent proteolysis YKR003W OSH6 similarity to KES1P, HES1P and OSH1P YKR009C FOX2 hydratase-dehydrogenase-epimerase, peroxisomal YKR031C SPO14 phospholipase D YKR053C YSR3 dihydrosphingosine-1-phosphate phosphatase YLL012W YLL012W similarity to triacylglycerol lipases YLL043W FPS1 glycerol channel protein YLL048C YBT1 yeast bile transporter YLR020C YLR020C similarity to triacylglycerol lipase YLR056W ERG3 C-5 sterol desaturase YLR058C SHM2 serine hydroxymethyltransferase, cytoplasmic YLR088W GAA1 required for attachment of GPI anchor onto proteins YLR099C ICT1 similarity to YDR125c YLR100W ERG27 3-keto sterol reductase YLR133W CKI1 choline kinase YLR189C UGT51 sterol glucosyltransferase (UDP-glucose:sterol glucosyltransferase) YLR195C NMT1 N-myristoyltransferase YLR240W VPS34 phosphatidylinositol 3-kinase YLR260W LCB5 sphingolipid long chain base kinase YLR284C ECI1 delta3-cis-delta2-trans-enoyl-CoA isomerase YLR305C STT4 phosphatidylinositol-4-kinase YLR372W SUR4 sterol isomerase, fatty acid elongase YLR380W CSR1 phosphatidylinositol transfer protein YLR450W HMG2 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 YML008C ERG6 S-adenosyl-methionine delta-24-sterol-c-methyltransferase YML042W CAT2 carnitine O-acetyltransferase YML075C HMG1 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 YML126C ERG13 3-hydroxy-3-methylglutaryl coenzyme A synthase YML131W YML131W similarity to human leukotriene b4 12-hydroxydehydrogenase YMR006C PLB2 strong similarity to PLB1P, YOL011w and P.notatum lysophospholipase YMR008C PLB1 phospholipase B (lysophospholipase) YMR013C SEC59 dolichol kinase YMR015C ERG5 C-22 sterol desaturase YMR043W MCM1 transcription factor of the MADS box family YMR060C TOM37 mitochondrial outer membrane import receptor subunit, 37 kD YMR079W SEC14 phosphatidylinositol(PI)/phosphatidylcholine(PC) transfer protein YMR202W ERG2 C-8 sterol isomerase YMR207C HFA1 strong similarity to acetyl-CoA carboxylase YMR208W ERG12 mevalonate kinase YMR220W ERG8 phosphomevalonate kinase YMR246W FAA4 long-chain-fatty-acid--CoA ligase YMR272C SCS7 required for hydroxylation of ceramide YMR281W GPI12 N-acetylglucosaminyl phosphatidylinositol deacetylase YMR296C LCB1 serine C-palmitoyltransferase subunit YMR307W GAS1 glycophospholipid-anchored surface glycoprotein YNL009W IDP3 isocitrate dehydrogenase, NADP-dependent YNL012W SPO1 transcriptional regulator involved in sporulation YNL040W YNL040W weak similarity to M.genitalium alanine--tRNA ligase YNL045W YNL045W strong similarity to human leukotriene-A4 hydrolase YNL106C INP52 phosphatidylinositol phosphate phosphatase YNL111C CYB5 cytochrome b5 YNL130C CPT1 diacylglycerol cholinephosphotransferase YNL169C PSD1 phosphatidylserine decarboxylase 1 YNL219C ALG9 mannosyltransferase YNL231C PDR16 protein involved in lipid biosynthesis and multidrug resistance YNL264C PDR17 involved in regulating phosphatidylserine metabolism YNL267W PIK1 phosphatidylinositol 4-kinase YNL280C ERG24 C-14 sterol reductase YNR008W LRO1 a lecithin cholesterol acyltransferase-like gene, mediates diacylglycerol esterification YNR016C ACC1 acetyl-CoA carboxylase YNR019W ARE2 acyl-CoA sterol acyltransferase YNR043W MVD1 mevalonate pyrophosphate decarboxylase YNR056C BIO5 similarity to choline transport protein HNM1P YOL004W SIN3 transcription regulatory protein YOL011W PLB3 phospholipase B (lysophospholipase) YOL065C INP54 inositol polyphosphate 5-phosphatase YOL103W ITR2 myo-inositol permease, minor YOL108C INO4 basic helix-loop-helix transcription factor YOR109W INP53 phosphatidylinositol phosphate phosphatase YOR153W PDR5 pleiotropic drug resistance protein YOR171C LCB4 sphingolipid long chain base kinase YOR180C DCI1 Enoyl-CoA Hydratase, peroxisomal YOR221C MCT1 malonyl-CoA:ACP transferase YOR237W HES1 involved in ergosterol biosynthesis YOR317W FAA1 long-chain-fatty-acid--CoA ligase YOR363C PIP2 peroxisome proliferating transcription factor YOR370C MRS6 geranylgeranyltransferase regulatory subunit YPL006W NCR1 similarity to human PTC protein involved in nevoid basal cell carcinoma syndrome YPL028W ERG10 acetyl-CoA C-acetyltransferase, cytosolic YPL057C SUR1 required for mannosylation of sphingolipids YPL069C BTS1 geranylgeranyl diphosphate synthase YPL076W GPI2 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein YPL087W YDC1 alkaline dihydroceramidase YPL117C IDI1 isopentenyl-diphosphate delta-isomerase YPL145C KES1 involved in ergosterol biosynthesis YPL147W PXA1 long-chain fatty acid transporter YPL148C PPT2 phosphopantetheine protein transferase YPL172C COX10 farnesyl transferase YPL175W SPT14 N-acetylglucosaminyltransferase YPL231W FAS2 fatty-acyl-CoA synthase, alpha chain YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YPR048W TAH18 similarity to M.domestica NADPH--ferrihemoprotein reductase and mammalian nitric-oxide synthases YPR113W PIS1 CDP diacylglycerol--inositol 3-phosphatidyltransferase YPR176C BET2 geranylgeranyltransferase type II beta subunit lipid, fatty-acid and isoprenoid biosynthesis (119 ORFs) 01.06.01 119 YAR042W SWH1 similarity to mammalian oxysterol-binding proteins YAR044W OSH1 similarity to human oxysterol binding protein (OSBP) YBL088C TEL1 telomere length control protein YBR029C CDS1 CDP-diacylglycerol synthase YBR042C CST26 weak similarity to 1-acyl-sn-glycerol-3-phosphate acyltransferase from Brassica napus YBR058C-A TSC3 required for optimal serine palmitoyltransferase activity YBR159W YBR159W similarity to human 17-beta-hydroxysteroid dehydrogenase YBR183W YPC1 Alkaline Ceramidase YBR222C FAT2 AMP-binding protein, peroxisomal YBR263W SHM1 serine hydroxymethyltransferase precursor, mitochondrial YBR265W TSC10 3-ketosphinganine reductase YCL004W PGS1 phosphatidylglycerophosphate synthase YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR048W ARE1 acyl-CoA sterol acyltransferase YDL015C TSC13 required for elongation of the very long chain fatty acid (VLCFA) moiety of sphingolipids YDL019C OSH2 similarity to SWH1P YDL052C SLC1 fatty acyltransferase YDL142C CRD1 cardiolipin synthase YDR062W LCB2 serine C-palmitoyltransferase subunit YDR072C IPT1 mannosyl diphosphorylinositol ceramide synthase YDR147W EKI1 ethanolamine kinase YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR287W YDR287W similarity to inositolmonophosphatases YDR294C DPL1 dihydrosphingosine phosphate lyase YDR297W SUR2 required for the hydroxylation of C-4 of the sphingoid moiety of ceramide YDR313C PIB1 phosphatidylinositol(3)-phosphate binding protein YDR376W ARH1 mitochondrial protein with similarity to human adrenodoxin reductase and ferredoxin-NADP+ reductase YER019W ISC1 weak similarity to human and mouse neutral sphingomyelinase YER026C CHO1 CDP-diacylglycerol serine O-phosphatidyltransferase YER044C ERG28 involved in synthesis of ergosterol YER061C CEM1 beta-keto-acyl-ACP synthase, mitochondrial YFR019W FAB1 phosphatidylinositol 3-phosphate 5-kinase YGL001C ERG26 C-3 sterol dehydrogenase (C-4 decarboxylase) YGL012W ERG4 sterol C-24 reductase YGL055W OLE1 stearoyl-CoA desaturase YGL126W SCS3 inositol phospholipid synthesis protein YGL142C GPI10 required for Glycosyl Phosphatdyl Inositol synthesis YGR007W MUQ1 choline phosphate cytidylyltransferase YGR037C ACB1 acyl-coenzyme-A-binding protein (diazepam binding inhibitor) YGR060W ERG25 C-4 sterol methyl oxidase YGR157W CHO2 phosphatidylethanolamine N-methyltransferase YGR170W PSD2 phosphatidylserine decarboxylase 2 YGR175C ERG1 squalene monooxygenase YGR202C PCT1 cholinephosphate cytidylyltransferase YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YHL003C LAG1 longevity-assurance protein YHR001W OSH7 similarity to KES1P YHR007C ERG11 cytochrome P450 lanosterol 14a-demethylase YHR042W NCP1 NADPH-cytochrome P450 reductase YHR046C YHR046C similarity to inositolmonophosphatases YHR072W ERG7 lanosterol synthase YHR073W OSH3 similarity to OSH1P, YDL019c and mammalian oxysterol-binding protei YHR123W EPT1 sn-1,2-diacylglycerol ethanolamine- and cholinephosphotransferase YHR190W ERG9 farnesyl-diphosphate farnesyltransferase YIL002C INP51 phosphatidylinositol phosphate 5-phosphatase YIL009W FAA3 acyl CoA synthase YIR035C YIR035C similarity to human corticosteroid 11-beta-dehydrogenase YJL134W LCB3 sphingoid base-phosphate phosphatase YJL167W ERG20 farnesyl-pyrophosphate synthetase YJL196C ELO1 fatty acid elongation protein YJR066W TOR1 phosphatidylinositol 3-kinase YJR073C OPI3 methylene-fatty-acyl-phospholipid synthase YKL004W AUR1 aureobasidin-resistance protein YKL182W FAS1 fatty-acyl-CoA synthase, beta chain YKL192C ACP1 mitochonrial acyl-carrier protein YKL203C TOR2 phosphatidylinositol 3-kinase YKR003W OSH6 similarity to KES1P, HES1P and OSH1P YKR053C YSR3 dihydrosphingosine-1-phosphate phosphatase YLR056W ERG3 C-5 sterol desaturase YLR058C SHM2 serine hydroxymethyltransferase, cytoplasmic YLR100W ERG27 3-keto sterol reductase YLR133W CKI1 choline kinase YLR189C UGT51 sterol glucosyltransferase (UDP-glucose:sterol glucosyltransferase) YLR240W VPS34 phosphatidylinositol 3-kinase YLR260W LCB5 sphingolipid long chain base kinase YLR305C STT4 phosphatidylinositol-4-kinase YLR372W SUR4 sterol isomerase, fatty acid elongase YLR450W HMG2 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 YML008C ERG6 S-adenosyl-methionine delta-24-sterol-c-methyltransferase YML042W CAT2 carnitine O-acetyltransferase YML075C HMG1 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 YML126C ERG13 3-hydroxy-3-methylglutaryl coenzyme A synthase YML131W YML131W similarity to human leukotriene b4 12-hydroxydehydrogenase YMR015C ERG5 C-22 sterol desaturase YMR060C TOM37 mitochondrial outer membrane import receptor subunit, 37 kD YMR202W ERG2 C-8 sterol isomerase YMR207C HFA1 strong similarity to acetyl-CoA carboxylase YMR220W ERG8 phosphomevalonate kinase YMR246W FAA4 long-chain-fatty-acid--CoA ligase YMR272C SCS7 required for hydroxylation of ceramide YMR281W GPI12 N-acetylglucosaminyl phosphatidylinositol deacetylase YMR296C LCB1 serine C-palmitoyltransferase subunit YNL045W YNL045W strong similarity to human leukotriene-A4 hydrolase YNL111C CYB5 cytochrome b5 YNL130C CPT1 diacylglycerol cholinephosphotransferase YNL169C PSD1 phosphatidylserine decarboxylase 1 YNL219C ALG9 mannosyltransferase YNL264C PDR17 involved in regulating phosphatidylserine metabolism YNL267W PIK1 phosphatidylinositol 4-kinase YNL280C ERG24 C-14 sterol reductase YNR008W LRO1 a lecithin cholesterol acyltransferase-like gene, mediates diacylglycerol esterification YNR016C ACC1 acetyl-CoA carboxylase YNR019W ARE2 acyl-CoA sterol acyltransferase YNR043W MVD1 mevalonate pyrophosphate decarboxylase YOR171C LCB4 sphingolipid long chain base kinase YOR221C MCT1 malonyl-CoA:ACP transferase YOR237W HES1 involved in ergosterol biosynthesis YOR317W FAA1 long-chain-fatty-acid--CoA ligase YPL028W ERG10 acetyl-CoA C-acetyltransferase, cytosolic YPL057C SUR1 required for mannosylation of sphingolipids YPL069C BTS1 geranylgeranyl diphosphate synthase YPL076W GPI2 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein YPL117C IDI1 isopentenyl-diphosphate delta-isomerase YPL145C KES1 involved in ergosterol biosynthesis YPL148C PPT2 phosphopantetheine protein transferase YPL175W SPT14 N-acetylglucosaminyltransferase YPL231W FAS2 fatty-acyl-CoA synthase, alpha chain YPR048W TAH18 similarity to M.domestica NADPH--ferrihemoprotein reductase and mammalian nitric-oxide synthases YPR113W PIS1 CDP diacylglycerol--inositol 3-phosphatidyltransferase phospholipid biosynthesis (2 ORFs) 01.06.01.01 2 YMR281W GPI12 N-acetylglucosaminyl phosphatidylinositol deacetylase YNL264C PDR17 involved in regulating phosphatidylserine metabolism glycolipid biosynthesis (1 ORF) 01.06.01.03 1 YMR281W GPI12 N-acetylglucosaminyl phosphatidylinositol deacetylase isoprenoid biosynthesis (1 ORF) 01.06.01.07 1 YER044C ERG28 involved in synthesis of ergosterol tetracyclic and pentacyclic triterpenes (cholesterin, steroids and hopanoids) biosynthesis (1 ORF) 01.06.01.07.11 1 YER044C ERG28 involved in synthesis of ergosterol breakdown of lipids, fatty acids and isoprenoids (25 ORFs) 01.06.04 25 YBR204C YBR204C weak similarity to peroxisomal serine-active lipase YDL109C YDL109C strong similarity to hypothetical protein YGL144c YDR058C TGL2 triacylglycerol lipase YDR444W YDR444W similarity to hypothetical protein YGL144c and YDL109c YDR452W PHM5 similarity to human sphingomyelin phosphodiesterase (PIR:S06957) YGL144C YGL144C strong similarity to hypothetical protein YDL109c YGL205W POX1 acyl-CoA oxidase YJL068C YJL068C strong similarity to human esterase D YJL132W YJL132W weak similarity to human phospholipase D YJR019C TES1 thioesterase, peroxisomal YJR107W YJR107W weak similarity to acylglycerol lipase YKL140W TGL1 triacylglycerol lipase YKL213C DOA1 involved in ubiquitin-dependent proteolysis YKR031C SPO14 phospholipase D YLL012W YLL012W similarity to triacylglycerol lipases YLR020C YLR020C similarity to triacylglycerol lipase YLR099C ICT1 similarity to YDR125c YLR284C ECI1 delta3-cis-delta2-trans-enoyl-CoA isomerase YMR006C PLB2 strong similarity to PLB1P, YOL011w and P.notatum lysophospholipase YMR008C PLB1 phospholipase B (lysophospholipase) YNL009W IDP3 isocitrate dehydrogenase, NADP-dependent YNL012W SPO1 transcriptional regulator involved in sporulation YNL040W YNL040W weak similarity to M.genitalium alanine--tRNA ligase YOL011W PLB3 phospholipase B (lysophospholipase) YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase lipid, fatty-acid and isoprenoid utilization (26 ORFs) 01.06.07 26 YBR003W COQ1 hexaprenyl pyrophosphate synthetase precursor YBR041W FAT1 very long-chain fatty acyl-CoA synthetase YBR183W YPC1 Alkaline Ceramidase YDL040C NAT1 protein N-acetyltransferase subunit YDL078C MDH3 malate dehydrogenase, peroxisomal YDL090C RAM1 protein farnesyltransferase, beta subunit YDR331W GPI8 essential for GPI anchor attachment YDR410C STE14 farnesyl cysteine carboxyl-methyltransferase YER015W FAA2 long-chain-fatty-acid--CoA ligase YFL014W HSP12 heat shock protein YGL155W CDC43 geranylgeranyltransferase beta subunit YHR013C ARD1 protein N-acetyltransferase subunit YIL009W FAA3 acyl CoA synthase YIL160C POT1 acetyl-CoA C-acyltransferase, peroxisomal YJL031C BET4 geranylgeranyl transferase, alpha chain YKL019W RAM2 protein farnesyltransferase, alpha subunit YKR009C FOX2 hydratase-dehydrogenase-epimerase, peroxisomal YLR088W GAA1 required for attachment of GPI anchor onto proteins YLR195C NMT1 N-myristoyltransferase YMR013C SEC59 dolichol kinase YMR246W FAA4 long-chain-fatty-acid--CoA ligase YOR180C DCI1 Enoyl-CoA Hydratase, peroxisomal YOR317W FAA1 long-chain-fatty-acid--CoA ligase YOR370C MRS6 geranylgeranyltransferase regulatory subunit YPL172C COX10 farnesyl transferase YPR176C BET2 geranylgeranyltransferase type II beta subunit regulation of lipid, fatty-acid and isoprenoid metabolism (20 ORFs) 01.06.10 20 YAL013W DEP1 regulator of phospholipid metabolism YAL051W OAF1 peroxisome proliferating transcription factor YBL015W ACH1 acetyl-CoA hydrolase YCL026C-A FRM2 involved in fatty acid regulation YCR028C FEN2 high affinity H+/pantothenate symporter YDR123C INO2 basic helix-loop-helix (BHLH) transcription factor YDR207C UME6 negative transcriptional regulator YDR284C DPP1 diacylglycerol pyrophosphate phosphatase YDR503C LPP1 lipid phosphate phosphatase YFL031W HAC1 transcription factor YGL162W SUT1 hypoxic protein involved in sterol uptake YHL020C OPI1 negative regulator of phospholipid biosynthesis pathway YHR079C IRE1 protein kinase YMR043W MCM1 transcription factor of the MADS box family YMR207C HFA1 strong similarity to acetyl-CoA carboxylase YMR208W ERG12 mevalonate kinase YNL231C PDR16 protein involved in lipid biosynthesis and multidrug resistance YOL004W SIN3 transcription regulatory protein YOL108C INO4 basic helix-loop-helix transcription factor YOR363C PIP2 peroxisome proliferating transcription factor lipid and fatty-acid transport (21 ORFs) 01.06.13 21 YAR035W YAT1 carnitine acetyltransferase, mitochondrial YCL043C PDI1 protein disulfide-isomerase precursor YCR098C GIT1 glycerophosphoinositol transporter YDR011W SNQ2 multidrug resistance protein YDR497C ITR1 myo-inositol permease, major YER015W FAA2 long-chain-fatty-acid--CoA ligase YER024W YAT2 carnitine O-acetyltransferase YGR037C ACB1 acyl-coenzyme-A-binding protein (diazepam binding inhibitor) YJL145W YJL145W weak similarity to T.pacificus retinal-binding protein YKL174C YKL174C similarity to choline transport protein HNM1P YKL188C PXA2 ABC transporter, peroxisomal YLL048C YBT1 yeast bile transporter YLR380W CSR1 phosphatidylinositol transfer protein YMR079W SEC14 phosphatidylinositol(PI)/phosphatidylcholine(PC) transfer protein YMR246W FAA4 long-chain-fatty-acid--CoA ligase YNL231C PDR16 protein involved in lipid biosynthesis and multidrug resistance YNR056C BIO5 similarity to choline transport protein HNM1P YOL103W ITR2 myo-inositol permease, minor YOR153W PDR5 pleiotropic drug resistance protein YPL147W PXA1 long-chain fatty acid transporter YPL148C PPT2 phosphopantetheine protein transferase other lipid, fatty-acid and isoprenoid metabolism activities (13 ORFs) 01.06.99 13 YBR036C CSG2 calcium dependent regulatory protein YBR067C TIP1 esterase YDR213W UPC2 regulatory protein involved in control of sterol uptake YDR302W GPI11 GPI11 - protein involved in glycosylphosphatidylinositol (GPI) biosynthesis YIL002C INP51 phosphatidylinositol phosphate 5-phosphatase YKL055C OAR1 putative 3-oxoacyl-(acyl carrier protein) reductase YLL043W FPS1 glycerol channel protein YMR307W GAS1 glycophospholipid-anchored surface glycoprotein YNL106C INP52 phosphatidylinositol phosphate phosphatase YNL264C PDR17 involved in regulating phosphatidylserine metabolism YOL065C INP54 inositol polyphosphate 5-phosphatase YOR109W INP53 phosphatidylinositol phosphate phosphatase YPL006W NCR1 similarity to human PTC protein involved in nevoid basal cell carcinoma syndrome metabolism of vitamins, cofactors, and prosthetic groups (86 ORFs) 01.07 86 YAL039C CYC3 holocytochrome-c synthase (cytochrome c heme lyase) YBL033C RIB1 GTP cyclohydrolase II YBL098W YBL098W similarity to human and D.melanogaster kynurenine 3-monooxygenase YBR003W COQ1 hexaprenyl pyrophosphate synthetase precursor YBR035C PDX3 pyridoxamine-phosphate oxidase YBR084W MIS1 C1-tetrahydrofolate synthase precursor, mitochondrial YBR092C PHO3 constitutive acid phosphatase precursor YBR093C PHO5 repressible acid phosphatase precursor YBR153W RIB7 HTP reductase YBR176W ECM31 involved in cell wall biogenesis and architecture YBR256C RIB5 riboflavin synthase, alpha chain YDL036C YDL036C strong similarity to RIB2 protein YDL045C FAD1 flavin adenine dinucleotide (FAD) synthetase YDL080C THI3 positive regulation factor of thiamin metabolism YDL141W BPL1 biotin holocarboxylase synthetase YDL205C HEM3 porphobilinogen deaminase YDR044W HEM13 coproporphyrinogen III oxidase YDR047W HEM12 uroporphyrinogen decarboxylase YDR204W COQ4 responsible for restoring ubiquinone biosynthesis in COQ4 mutant YDR232W HEM1 5-aminolevulinate synthase YDR487C RIB3 3,4-dihydroxy-2-butanone 4-phosphate synthase YDR541C YDR541C similarity to dihydroflavonol-4-reductases YER014W HEM14 protoporphyrinogen oxidase, mitochondrial YER043C SAH1 S-adenosyl-L-homocysteine hydrolase YER183C FAU1 similarity to human 5,10-methenyltetrahydrofolate synthetase YFR047C YFR047C strong similarity to human quinolinate phosphoribosyltransferase YGL039W YGL039W similarity to V. vinifera dihydroflavonol reductase YGL040C HEM2 porphobilinogen synthase YGL125W MET13 putative methylene tetrahydrofolate reductase YGL157W YGL157W similarity to V.vinifera dihydroflavonol 4-reductase YGR144W THI4 involved in thiamine biosynthesis and DNA repair YGR169C YGR169C similarity to RIB2P YGR204W ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YGR255C COQ6 monooxygenase YGR267C FOL2 GTP cyclohydrolase I YGR286C BIO2 biotin synthetase YHL018W YHL018W similarity to human pterin-4-alpha-carbinolamine dehydratase YHR003C YHR003C strong similarity to molybdopterin-converting factor homolog YKL027w YHR063C PAN5 weak similarity to translational activator CBS2 YHR111W YHR111W similarity to molybdopterin biosynthesis proteins YIL006W YIL006W similarity to FLX1P YIL098C FMC1 Formation of Mitochondrial Cytochromes YIL134W FLX1 FAD carrier protein (MCF), mitochondrial YIL145C PAN6 protein required for synthesis of pantothenic acid YJR025C BNA1 3-hydroxyanthranilic acid dioxygenase YJR078W YJR078W similarity to mammalian indoleamine 2,3-dioxygenase YJR142W YJR142W similarity to thiamin pyrophosphokinase YKL027W YKL027W similarity to E.coli molybdopterin-converting factor chlN YKL087C CYT2 holocytochrome-c1 synthase YKL132C RMA1 similarity to B.subtilis folC protein and strong similarity to YMR113w YKR069W MET1 siroheme synthase YLR151C PCD1 peroxisomal nudix hydrolase, has diphosphatase activity specific for coenzyme A and CoA derivatives YLR205C HMX1 weak similarity to heme oxygenase 'Rhodella violacea HO_RHOVL' YLR231C YLR231C strong similarity to rat kynureninase YLR237W THI7 thiamin transport protein YLR239C LIP2 lipoic acid ligase YML110C COQ5 ubiquinone biosynthesis, methyltransferase YMR020W FMS1 involved in the biosynthesis of pantothenic acid YMR113W FOL3 dihydrofolate synthetase YMR222C YMR222C similarity to S.pombe dihydrofolate reductase YNL256W FOL1 Dihydroneopterin aldolase, dihydro-6-hydroxymethylpterin pyrophosphokinase, dihydropteroate synthetase YNL333W SNZ2 putative pyridoxine (vitamin B6) biosynthetic enzyme YNR027W BUD17 similarity to human pyridoxal kinase YNR033W ABZ1 para-aminobenzoate synthase YNR041C COQ2 para-hydroxybenzoate--polyprenyltransferase YNR057C BIO4 putative dethiobiotin synthetase YNR058W BIO3 DAPA aminotransferase YOL049W GSH2 Glutathione synthetase YOL066C RIB2 DRAP deaminase YOL096C COQ3 enzyme of ubiquinone (coenzyme Q) biosynthesis YOL143C RIB4 6,7-dimethyl-8-ribityllumazine synthase YOL151W GRE2 similarity to plant dihydroflavonol-4-reductases YOR125C CAT5 involved in coenzyme Q (ubiquinone) biosynthesis YOR143C THI80 thiamin pyrophosphokinase YOR176W HEM15 ferrochelatase precursor YOR184W SER1 phosphoserine transaminase YOR196C LIP5 lipoic acid synthase YOR209C NPT1 nicotinate phosphoribosyltransferase YOR236W DFR1 dihydrofolate reductase YOR241W MET7 tetrahydrofolylpolyglutamate synthase YOR278W HEM4 uroporphyrinogen III synthase YPL023C MET12 methylenetetrahydrofolate reductase YPL132W COX11 cytochrome-c oxidase assembly protein YPL172C COX10 farnesyl transferase YPL214C THI6 thiamin-phosphate pyrophosphorylase and hydroxyethylthiazole kinase YPR065W ROX1 heme-dependent transcriptional repressor of hypoxic genes biosynthesis of vitamins, cofactors, and prosthetic groups (63 ORFs) 01.07.01 63 YBL033C RIB1 GTP cyclohydrolase II YBL098W YBL098W similarity to human and D.melanogaster kynurenine 3-monooxygenase YBR003W COQ1 hexaprenyl pyrophosphate synthetase precursor YBR035C PDX3 pyridoxamine-phosphate oxidase YBR084W MIS1 C1-tetrahydrofolate synthase precursor, mitochondrial YBR153W RIB7 HTP reductase YBR176W ECM31 involved in cell wall biogenesis and architecture YBR256C RIB5 riboflavin synthase, alpha chain YDL036C YDL036C strong similarity to RIB2 protein YDL045C FAD1 flavin adenine dinucleotide (FAD) synthetase YDL205C HEM3 porphobilinogen deaminase YDR044W HEM13 coproporphyrinogen III oxidase YDR047W HEM12 uroporphyrinogen decarboxylase YDR204W COQ4 responsible for restoring ubiquinone biosynthesis in COQ4 mutant YDR232W HEM1 5-aminolevulinate synthase YDR487C RIB3 3,4-dihydroxy-2-butanone 4-phosphate synthase YER014W HEM14 protoporphyrinogen oxidase, mitochondrial YER043C SAH1 S-adenosyl-L-homocysteine hydrolase YFR047C YFR047C strong similarity to human quinolinate phosphoribosyltransferase YGL039W YGL039W similarity to V. vinifera dihydroflavonol reductase YGL040C HEM2 porphobilinogen synthase YGL125W MET13 putative methylene tetrahydrofolate reductase YGR204W ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YGR255C COQ6 monooxygenase YGR267C FOL2 GTP cyclohydrolase I YGR286C BIO2 biotin synthetase YHR003C YHR003C strong similarity to molybdopterin-converting factor homolog YKL027w YHR063C PAN5 weak similarity to translational activator CBS2 YHR111W YHR111W similarity to molybdopterin biosynthesis proteins YIL145C PAN6 protein required for synthesis of pantothenic acid YJR025C BNA1 3-hydroxyanthranilic acid dioxygenase YJR078W YJR078W similarity to mammalian indoleamine 2,3-dioxygenase YJR142W YJR142W similarity to thiamin pyrophosphokinase YKL027W YKL027W similarity to E.coli molybdopterin-converting factor chlN YKR069W MET1 siroheme synthase YLR231C YLR231C strong similarity to rat kynureninase YML110C COQ5 ubiquinone biosynthesis, methyltransferase YMR020W FMS1 involved in the biosynthesis of pantothenic acid YMR113W FOL3 dihydrofolate synthetase YMR222C YMR222C similarity to S.pombe dihydrofolate reductase YNL256W FOL1 Dihydroneopterin aldolase, dihydro-6-hydroxymethylpterin pyrophosphokinase, dihydropteroate synthetase YNL333W SNZ2 putative pyridoxine (vitamin B6) biosynthetic enzyme YNR033W ABZ1 para-aminobenzoate synthase YNR041C COQ2 para-hydroxybenzoate--polyprenyltransferase YNR057C BIO4 putative dethiobiotin synthetase YNR058W BIO3 DAPA aminotransferase YOL049W GSH2 Glutathione synthetase YOL066C RIB2 DRAP deaminase YOL096C COQ3 enzyme of ubiquinone (coenzyme Q) biosynthesis YOL143C RIB4 6,7-dimethyl-8-ribityllumazine synthase YOL151W GRE2 similarity to plant dihydroflavonol-4-reductases YOR143C THI80 thiamin pyrophosphokinase YOR176W HEM15 ferrochelatase precursor YOR184W SER1 phosphoserine transaminase YOR196C LIP5 lipoic acid synthase YOR209C NPT1 nicotinate phosphoribosyltransferase YOR236W DFR1 dihydrofolate reductase YOR241W MET7 tetrahydrofolylpolyglutamate synthase YOR278W HEM4 uroporphyrinogen III synthase YPL023C MET12 methylenetetrahydrofolate reductase YPL132W COX11 cytochrome-c oxidase assembly protein YPL172C COX10 farnesyl transferase YPL214C THI6 thiamin-phosphate pyrophosphorylase and hydroxyethylthiazole kinase utilization of vitamins, cofactors, and prosthetic groups (7 ORFs) 01.07.04 7 YAL039C CYC3 holocytochrome-c synthase (cytochrome c heme lyase) YBR092C PHO3 constitutive acid phosphatase precursor YBR093C PHO5 repressible acid phosphatase precursor YDL141W BPL1 biotin holocarboxylase synthetase YKL087C CYT2 holocytochrome-c1 synthase YKL132C RMA1 similarity to B.subtilis folC protein and strong similarity to YMR113w YNR027W BUD17 similarity to human pyridoxal kinase regulation of vitamins, cofactors, and prosthetic groups metabolism (3 ORFs) 01.07.07 3 YDL080C THI3 positive regulation factor of thiamin metabolism YOR125C CAT5 involved in coenzyme Q (ubiquinone) biosynthesis YPR065W ROX1 heme-dependent transcriptional repressor of hypoxic genes transport of vitamins, cofactors, and prosthetic groups (3 ORFs) 01.07.10 3 YIL006W YIL006W similarity to FLX1P YIL134W FLX1 FAD carrier protein (MCF), mitochondrial YLR237W THI7 thiamin transport protein other vitamin, cofactor, and prosthetic group metabolism activities (8 ORFs) 01.07.99 8 YDR541C YDR541C similarity to dihydroflavonol-4-reductases YER183C FAU1 similarity to human 5,10-methenyltetrahydrofolate synthetase YGL157W YGL157W similarity to V.vinifera dihydroflavonol 4-reductase YGR144W THI4 involved in thiamine biosynthesis and DNA repair YGR169C YGR169C similarity to RIB2P YHL018W YHL018W similarity to human pterin-4-alpha-carbinolamine dehydratase YIL098C FMC1 Formation of Mitochondrial Cytochromes YLR151C PCD1 peroxisomal nudix hydrolase, has diphosphatase activity specific for coenzyme A and CoA derivatives secondary metabolism (5 ORFs) 01.20 5 YKL184W SPE1 ornithine decarboxylase YLL031C GPI13 protein involved in glycosylphosphatidylinositol biosynthesis YLR146C SPE4 spermine synthase YOL052C SPE2 adenosylmethionine decarboxylase precursor YPR069C SPE3 putrescine aminopropyltransferase (spermidine synthase) metabolism of primary metabolic sugars derivatives (1 ORF) 01.20.01 1 YLL031C GPI13 protein involved in glycosylphosphatidylinositol biosynthesis biosynthesis of glycosides (1 ORF) 01.20.01.07 1 YLL031C GPI13 protein involved in glycosylphosphatidylinositol biosynthesis biosynthesis of secondary products derived from primary amino acids (4 ORFs) 01.20.17 4 YKL184W SPE1 ornithine decarboxylase YLR146C SPE4 spermine synthase YOL052C SPE2 adenosylmethionine decarboxylase precursor YPR069C SPE3 putrescine aminopropyltransferase (spermidine synthase) biosynthesis of amines (4 ORFs) 01.20.17.03 4 YKL184W SPE1 ornithine decarboxylase YLR146C SPE4 spermine synthase YOL052C SPE2 adenosylmethionine decarboxylase precursor YPR069C SPE3 putrescine aminopropyltransferase (spermidine synthase) ENERGY (252 ORFs) 02 252 YAL038W CDC19 pyruvate kinase YAL054C ACS1 acetyl-CoA synthetase YAL061W FUN50 similarity to alcohol/sorbitol dehydrogenase YBL045C COR1 ubiquinol--cytochrome-c reductase 44K core protein YBL058W SHP1 potential regulatory subunit for GLC7P YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBR001C NTH2 alpha,alpha-trehalase YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR117C TKL2 transketolase 2 YBR126C TPS1 alpha,alpha-trehalose-phosphate synthase, 56 KD subunit YBR145W ADH5 alcohol dehydrogenase V YBR185C MBA1 respiratory chain assembly protein YBR192W RIM2 mitochondrial carrier protein (MCF) YBR196C PGI1 glucose-6-phosphate isomerase YBR218C PYC2 pyruvate carboxylase 2 YBR221C PDB1 pyruvate dehydrogenase (lipoamide) beta chain precursor YBR229C ROT2 glucosidase II, catalytic subunit YBR299W MAL32 alpha-glucosidase YCL040W GLK1 aldohexose specific glucokinase YCR005C CIT2 citrate (si)-synthase, peroxisomal YCR012W PGK1 phosphoglycerate kinase YCR046C IMG1 ribosomal protein, mitochondrial YCR105W YCR105W strong similarity to alcohol dehydrogenases YCR107W AAD3 strong similarity aryl-alcohol reductases of P. chrysosporium YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL021W GPM2 phosphoglycerate mutase YDL066W IDP1 isocitrate dehydrogenase (NADP+), mitochondrial YDL067C COX9 cytochrome-c oxidase chain VIIA YDL078C MDH3 malate dehydrogenase, peroxisomal YDL085W NDH2 mitochondrial NADH dehydrogenase that catalyzes the oxidation of cytosolic NADH YDL107W MSS2 ser/thr protein kinase YDL130W-A STF1 ATPase stabilizing factor, 10 kDa YDL174C DLD1 D-lactate ferricytochrome C oxidoreductase (D-LCR) YDL181W INH1 inhibitor of mitochondrial ATPase YDL243C AAD4 strong similarity to aryl-alcohol dehydrogenase YDR001C NTH1 neutral trehalase (alpha,alpha-trehalase) YDR050C TPI1 triose-phosphate isomerase YDR074W TPS2 alpha,alpha-trehalose-phosphate synthase, 102 KD subunit YDR079W PET100 cytochrome-c oxidase assembly protein YDR081C PDC2 pyruvate decarboxylase regulatory protein YDR148C KGD2 2-oxoglutarate dehydrogenase complex E2 component YDR178W SDH4 succinate dehydrogenase membrane anchor subunit for SDH2P YDR231C COX20 in the maturation and assembly of cytochrome oxidase involved protein YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR322C-A TIM11 subunit E of the dimeric form of mitochondrial F1F0-ATPase YDR377W ATP17 ATP synthase complex, subunit f YDR380W ARO10 similarity to PDC6P, THI3P and to pyruvate decarboxylases YDR384C YDR384C strong similarity to Y.lipolytica GPR1 gene YDR529C QCR7 ubiquinol--cytochrome-c reductase subunit 7 YEL011W GLC3 1,4-glucan branching enzyme (glycogen branching enzyme) YEL020C YEL020C similarity to O.formigenes oxalyl-CoA decarboxylase YEL024W RIP1 ubiquinol--cytochrome-c reductase iron-sulfur protein precursor YEL039C CYC7 cytochrome-c isoform 2 YEL047C FRDS1 soluble fumarate reductase, cytoplasmic YEL053C MAK10 glucose-repressible protein YEL071W DLD3 D-lactate dehydrogenase YER054C GIP2 GLC7P-interacting protein YER061C CEM1 beta-keto-acyl-ACP synthase, mitochondrial YER065C ICL1 isocitrate lyase YER073W ALD5 aldehyde dehydrogenase (NAD+), mitochondrial YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER141W COX15 cytochrome oxidase assembly factor YER154W OXA1 cytochrome oxidase biogenesis protein YER178W PDA1 pyruvate dehydrogenase (lipoamide) alpha chain precursor YFL018C LPD1 dihydrolipoamide dehydrogenase precursor YFL056C AAD6 strong similarity to aryl-alcohol dehydrogenases YFL057C YFL057C strong similarity to aryl-alcohol dehydrogenases YFR015C GSY1 UDP glucose--starch glucosyltransferase, isoform 1 YFR033C QCR6 ubiquinol--cytochrome-c reductase 17K protein YFR053C HXK1 hexokinase I YGL018C JAC1 molecular chaperone YGL062W PYC1 pyruvate carboxylase 1 YGL119W ABC1 ubiquinol--cytochrome-c reductase complex assembly protein YGL134W PCL10 cyclin like protein interacting with PHO85P YGL187C COX4 cytochrome-c oxidase chain IV YGL191W COX13 cytochrome-c oxidase chain VIa YGL205W POX1 acyl-CoA oxidase YGL226W YGL226W similarity to N.crassa cytochrome-c oxidase chain V YGL253W HXK2 hexokinase II YGL256W ADH4 alcohol dehydrogenase IV YGR008C STF2 ATPase stabilizing factor YGR043C YGR043C strong similarity to transaldolase YGR062C COX18 required for activity of mitochondrial cytochrome oxidase YGR087C PDC6 pyruvate decarboxylase 3 YGR112W SHY1 SURF homologue protein YGR174C CBP4 ubiquinol--cytochrome-c reductase assembly factor YGR183C QCR9 ubiquinol--cytochrome-c reductase subunit 9 YGR192C TDH3 glyceraldehyde-3-phosphate dehydrogenase 3 YGR193C PDX1 pyruvate dehydrogenase complex protein X YGR207C ETF-BETA electron-transferring flavoprotein, beta chain YGR240C PFK1 6-phosphofructokinase, alpha subunit YGR244C LSC2 succinate-CoA ligase beta subunit YGR254W ENO1 enolase I (2-phosphoglycerate dehydratase) YGR256W GND2 phosphogluconate dehydrogenase YHL008C YHL008C similarity to M.formicicum formate dehydrogenase YHR001W-A QCR10 ubiquinol--cytochrome-c reductase 8.5 kDa subunit YHR039C MSC7 similarity to aldehyde dehydrogenases YHR047C AAP1' alanine/arginine aminopeptidase YHR051W COX6 cytochrome-c oxidase subunit VI YHR076W YHR076W weak similarity to C.elegans hypothetical protein CEW09D10 YHR174W ENO2 enolase II (2-phosphoglycerate dehydratase) YHR179W OYE2 NADPH dehydrogenase (old yellow enzyme), isoform 1 YHR183W GND1 6-phosphogluconate dehydrogenase YHR188C GPI16 similarity to hypothetical C. elegans proteins F17c11.7 YIL043C CBR1 cytochrome-b5 reductase YIL045W PIG2 Protein Interacting with GSY2P YIL111W COX5B cytochrome-c oxidase chain Vb YIL125W KGD1 2-oxoglutarate dehydrogenase complex E1 component YIL160C POT1 acetyl-CoA C-acyltransferase, peroxisomal YIL172C YIL172C identical to FSP2P and similarity to other alpha-glucosidases YIR031C DAL7 malate synthase 2 YJL045W YJL045W strong similarity to succinate dehydrogenase flavoprotein YJL052W TDH1 glyceraldehyde-3-phosphate dehydrogenase 1 YJL121C RPE1 D-ribulose-5-phosphate 3-epimerase YJL137C GLG2 self-glucosylating initiator of glycogen synthesis YJL166W QCR8 ubiquinol--cytochrome-c reductase chain VIII YJL200C YJL200C strong similarity to aconitate hydratase YJL216C YJL216C strong similarity to Mal62p YJL221C FSP2 strong similarity to alpha-D-glucosidase YJR009C TDH2 glyceraldehyde-3-phosphate dehydrogenase 2 YJR033C RAV1 similarity to Drosophila DmX gene YJR034W PET191 involved in assembly of cytochrome oxidase YJR048W CYC1 cytochrome-c isoform 1 YJR051W OSM1 osmotic growth protein YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YJR155W AAD10 strong similarity to aryl-alcohol dehydrogenase YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL035W UGP1 UTP--glucose-1-phosphate uridylyltransferase YKL039W PTM1 member of the major facilitator superfamily YKL055C OAR1 putative 3-oxoacyl-(acyl carrier protein) reductase YKL060C FBA1 fructose-bisphosphate aldolase YKL085W MDH1 malate dehydrogenase precursor, mitochondrial YKL127W PGM1 phosphoglucomutase, minor isoform YKL128C PMU1 high copy suppressor of ts TPS2 mutant phenotype YKL141W SDH3 cytochrome b560 subunit of respiratory complex II YKL148C SDH1 succinate dehydrogenase flavoprotein precursor YKL150W MCR1 cytochrome-b5 reductase YKL152C GPM1 phosphoglycerate mutase YKR009C FOX2 hydratase-dehydrogenase-epimerase, peroxisomal YKR016W YKR016W weak similarity to mysoin heavy chain proteins YKR043C YKR043C weak similarity to phosphoglycerate mutase YKR046C YKR046C hypothetical protein YKR058W GLG1 self-glycosylating initiator of glycogen synthesis YKR096W YKR096W similarity to mitochondrial aldehyde dehydrogenase Ald1p YKR097W PCK1 phosphoenolpyruvate carboxykinase YLL009C COX17 interacts genetically with SCO1 and SCO2 in cytochrome oxidase assembly YLL041C SDH2 succinate dehydrogenase iron-sulfur protein subunit YLR038C COX12 cytochrome-c oxidase, subunit VIB YLR044C PDC1 pyruvate decarboxylase, isozyme 1 YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR134W PDC5 pyruvate decarboxylase, isozyme 2 YLR153C ACS2 acetyl-coenzyme A synthetase YLR164W YLR164W strong similarity to SDH4P YLR174W IDP2 isocitrate dehydrogenase, cytosolic YLR248W RCK2 Ca/calmodulin-dependent ser/thr protein kinase YLR258W GSY2 UDP-glucose--starch glucosyltransferase, isoform 2 YLR273C PIG1 putative type 1 phosphatase regulatory subunit YLR284C ECI1 delta3-cis-delta2-trans-enoyl-CoA isomerase YLR295C ATP14 F1F0-ATPase complex, subunit h YLR304C ACO1 aconitate hydratase YLR345W YLR345W similarity to PFK26P and other 6-phosphofructo-2-kinases YLR354C TAL1 transaldolase YLR377C FBP1 fructose-1,6-bisphosphatase YLR395C COX8 cytochrome-c oxidase chain VIII YML035C AMD1 AMP deaminase YML054C CYB2 lactate dehydrogenase cytochrome b2 YML081C-A ATP18 gene for subunit i/j of the mitochondrial F1F0-ATP synthase YML087C YML087C strong similarity to YML125c, similarity to cytochrome-b5- and nitrate reductases YML100W TSL1 alpha,alpha-trehalose-phosphate synthase, 123 KD subunit YML120C NDI1 NADH-ubiquinone-6 oxidoreductase YML125C YML125C strong similarity to cytochrome-b5- and nitrate reductases YML129C COX14 cytochrome-c oxidase assembly protein YMR073C YMR073C weak similarity to C-terminal part of cytochrome b5 and b2 YMR089C YTA12 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YMR105C PGM2 phosphoglucomutase, major isoform YMR116C ASC1 40S small subunit ribosomal protein YMR118C YMR118C strong similarity to succinate dehydrogenase YMR145C NDH1 mitochondrial cytosolically directed NADH dehydrogenase YMR165C SMP2 involved in plasmid maintenance, respiration and cell proliferation YMR169C ALD3 stress inducible aldehyde dehydrogenase YMR170C ALD2 aldehyde dehydrogenase 2 (NAD+) YMR205C PFK2 6-phosphofructokinase, beta subunit YMR244W YMR244W similarity to UTH1P, NCA3P, YIL123w and SUN4P YMR256C COX7 cytochrome-c oxidase, subunit VII YMR261C TPS3 alpha,alpha-trehalose-phosphate synthase, 115 KD subunit YMR267W PPA2 inorganic pyrophosphatase, mitochondrial YMR280C CAT8 transcription factor involved in gluconeogenesis YMR282C AEP2 required for the expression of subunit-9 of atp synthase YMR285C NGL2 similarity to CCR4P YMR303C ADH2 alcohol dehydrogenase II YMR318C YMR318C strong similarity to alcohol-dehydrogenase YMR323W YMR323W strong similarity to phosphopyruvate hydratases YNL009W IDP3 isocitrate dehydrogenase, NADP-dependent YNL037C IDH1 isocitrate dehydrogenase (NAD+) subunit 1, mitochondrial YNL052W COX5A cytochrome-c oxidase chain V.A precursor YNL071W LAT1 dihydrolipoamide S-acetyltransferase YNL117W MLS1 malate synthase 1 YNL118C DCP2 suppressor protein of a yeast pet mutant YNL202W SPS19 peroxisomal 2,4-dienoyl-CoA reductase YNL237W YTP1 weak similarity to mitochondrial electron transport proteins YNL241C ZWF1 glucose-6-phosphate dehydrogenase YNL331C AAD14 strong similarity aryl-alcohol reductase YNR001C CIT1 citrate (si)-synthase, mitochondrial YNR032W PPG1 phosphoprotein phosphatase PPG catalytic chain YOL056W GPM3 phosphoglycerate mutase YOL077W-A ATP19 subunit K of the dimeric form of mitochondrial F1F0-ATP synthase YOL079W YOL079W similarity to NADH dehydrogenases YOL086C ADH1 alcohol dehydrogenase I YOL126C MDH2 malate dehydrogenase, cytoplasmic YOL157C YOL157C strong similarity to alpha-glucosidases YOL165C AAD15 putative aryl alcohol dehydrogenase YOR065W CYT1 cytochrome-c1 YOR095C RKI1 D-ribose-5-phosphate ketol-isomerase YOR126C IAH1 isoamyl acetate hydrolytic enzyme YOR136W IDH2 isocitrate dehydrogenase (NAD+) subunit 2, mitochondrial YOR142W LSC1 succinate-CoA ligase alpha subunit YOR178C GAC1 ser/thr phosphoprotein phosphatase 1, regulatory chain YOR221C MCT1 malonyl-CoA:ACP transferase YOR283W YOR283W weak similarity to phosphoglycerate mutases YOR347C PYK2 pyruvate kinase, glucose-repressed isoform YOR356W YOR356W strong similarity to human electron transfer flavoprotein-ubiquinone oxidoreductase YOR388C FDH1 strong similarity to H.polymorpha formate dehydrogenase YOR393W ERR1 enolase related protein YPL031C PHO85 cyclin-dependent protein kinase YPL061W ALD6 aldehyde dehydrogenase, cytosolic YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL088W YPL088W similarity to aryl-alcohol dehydrogenases YPL171C OYE3 NAPDH dehydrogenase (old yellow enzyme), isoform 3 YPL219W PCL8 cyclin like protein interacting with PHO85P YPL240C HSP82 heat shock protein YPL262W FUM1 fumarate hydratase YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPL275W YPL275W identical to a region of YOR388c YPL276W YPL276W identical to a region of YOR388c YPL281C ERR2 enolase related protein YPR001W CIT3 citrate (si)-synthase, mitochondrial YPR004C YPR004C strong similarity to electron transfer flavoproteins alpha chain YPR006C ICL2 non-functional isocitrate lyase YPR020W ATP20 subunit G of the dimeric form of mitochondrial F1F0-ATP Synthase YPR026W ATH1 acid trehalase, vacuolar YPR048W TAH18 similarity to M.domestica NADPH--ferrihemoprotein reductase and mammalian nitric-oxide synthases YPR074C TKL1 transketolase 1 YPR160W GPH1 glycogen phosphorylase YPR184W GDB1 similarity to human 4-alpha-glucanotransferase (EC 2.4.1.25)/amylo-1,6-glucosidase (EC 3.2.1.33) YPR191W QCR2 ubiquinol--cytochrome-c reductase 40KD chain II Q0045 COX1 cytochrome-c oxidase subunit I Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0105 COB ubiquinol-cytochrome-c reductase subunit (cytochrome B) Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 Q0250 COX2 cytochrome-c oxidase subunit II Q0275 COX3 cytochrome-c oxidase chain III glycolysis and gluconeogenesis (35 ORFs) 02.01 35 YAL038W CDC19 pyruvate kinase YBR196C PGI1 glucose-6-phosphate isomerase YBR218C PYC2 pyruvate carboxylase 2 YBR221C PDB1 pyruvate dehydrogenase (lipoamide) beta chain precursor YCL040W GLK1 aldohexose specific glucokinase YCR012W PGK1 phosphoglycerate kinase YDL021W GPM2 phosphoglycerate mutase YDR050C TPI1 triose-phosphate isomerase YER065C ICL1 isocitrate lyase YER178W PDA1 pyruvate dehydrogenase (lipoamide) alpha chain precursor YFR053C HXK1 hexokinase I YGL062W PYC1 pyruvate carboxylase 1 YGL253W HXK2 hexokinase II YGR192C TDH3 glyceraldehyde-3-phosphate dehydrogenase 3 YGR193C PDX1 pyruvate dehydrogenase complex protein X YGR240C PFK1 6-phosphofructokinase, alpha subunit YGR254W ENO1 enolase I (2-phosphoglycerate dehydratase) YHR174W ENO2 enolase II (2-phosphoglycerate dehydratase) YJL052W TDH1 glyceraldehyde-3-phosphate dehydrogenase 1 YJR009C TDH2 glyceraldehyde-3-phosphate dehydrogenase 2 YKL060C FBA1 fructose-bisphosphate aldolase YKL152C GPM1 phosphoglycerate mutase YKR043C YKR043C weak similarity to phosphoglycerate mutase YKR097W PCK1 phosphoenolpyruvate carboxykinase YLR345W YLR345W similarity to PFK26P and other 6-phosphofructo-2-kinases YLR377C FBP1 fructose-1,6-bisphosphatase YMR205C PFK2 6-phosphofructokinase, beta subunit YMR280C CAT8 transcription factor involved in gluconeogenesis YMR323W YMR323W strong similarity to phosphopyruvate hydratases YNL071W LAT1 dihydrolipoamide S-acetyltransferase YOL056W GPM3 phosphoglycerate mutase YOR283W YOR283W weak similarity to phosphoglycerate mutases YOR347C PYK2 pyruvate kinase, glucose-repressed isoform YOR393W ERR1 enolase related protein YPL281C ERR2 enolase related protein pentose-phosphate pathway (9 ORFs) 02.07 9 YBR117C TKL2 transketolase 2 YGR043C YGR043C strong similarity to transaldolase YGR256W GND2 phosphogluconate dehydrogenase YHR183W GND1 6-phosphogluconate dehydrogenase YJL121C RPE1 D-ribulose-5-phosphate 3-epimerase YLR354C TAL1 transaldolase YNL241C ZWF1 glucose-6-phosphate dehydrogenase YOR095C RKI1 D-ribose-5-phosphate ketol-isomerase YPR074C TKL1 transketolase 1 tricarboxylic-acid pathway (citrate cycle, Krebs cycle, TCA cycle) (25 ORFs) 02.10 25 YDL066W IDP1 isocitrate dehydrogenase (NADP+), mitochondrial YDR148C KGD2 2-oxoglutarate dehydrogenase complex E2 component YDR178W SDH4 succinate dehydrogenase membrane anchor subunit for SDH2P YEL047C FRDS1 soluble fumarate reductase, cytoplasmic YFL018C LPD1 dihydrolipoamide dehydrogenase precursor YGR244C LSC2 succinate-CoA ligase beta subunit YHR188C GPI16 similarity to hypothetical C. elegans proteins F17c11.7 YIL125W KGD1 2-oxoglutarate dehydrogenase complex E1 component YJL045W YJL045W strong similarity to succinate dehydrogenase flavoprotein YJL200C YJL200C strong similarity to aconitate hydratase YJR051W OSM1 osmotic growth protein YKL039W PTM1 member of the major facilitator superfamily YKL085W MDH1 malate dehydrogenase precursor, mitochondrial YKL148C SDH1 succinate dehydrogenase flavoprotein precursor YLL041C SDH2 succinate dehydrogenase iron-sulfur protein subunit YLR164W YLR164W strong similarity to SDH4P YLR174W IDP2 isocitrate dehydrogenase, cytosolic YLR304C ACO1 aconitate hydratase YMR118C YMR118C strong similarity to succinate dehydrogenase YNL037C IDH1 isocitrate dehydrogenase (NAD+) subunit 1, mitochondrial YNR001C CIT1 citrate (si)-synthase, mitochondrial YOR136W IDH2 isocitrate dehydrogenase (NAD+) subunit 2, mitochondrial YOR142W LSC1 succinate-CoA ligase alpha subunit YPL262W FUM1 fumarate hydratase YPR001W CIT3 citrate (si)-synthase, mitochondrial electron transport and membrane-associated energy conservation (2 ORFs) 02.11 2 YDR231C COX20 in the maturation and assembly of cytochrome oxidase involved protein YJR033C RAV1 similarity to Drosophila DmX gene accessory proteins of electron transport and membrane-associated energy conservation (1 ORF) 02.11.05 1 YJR033C RAV1 similarity to Drosophila DmX gene other electron transport and membrane-associated energy conservation proteins (1 ORF) 02.11.99 1 YDR231C COX20 in the maturation and assembly of cytochrome oxidase involved protein respiration (88 ORFs) 02.13 88 YBL045C COR1 ubiquinol--cytochrome-c reductase 44K core protein YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR185C MBA1 respiratory chain assembly protein YBR192W RIM2 mitochondrial carrier protein (MCF) YCR046C IMG1 ribosomal protein, mitochondrial YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL067C COX9 cytochrome-c oxidase chain VIIA YDL085W NDH2 mitochondrial NADH dehydrogenase that catalyzes the oxidation of cytosolic NADH YDL107W MSS2 ser/thr protein kinase YDL130W-A STF1 ATPase stabilizing factor, 10 kDa YDR079W PET100 cytochrome-c oxidase assembly protein YDR178W SDH4 succinate dehydrogenase membrane anchor subunit for SDH2P YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR322C-A TIM11 subunit E of the dimeric form of mitochondrial F1F0-ATPase YDR377W ATP17 ATP synthase complex, subunit f YDR529C QCR7 ubiquinol--cytochrome-c reductase subunit 7 YEL024W RIP1 ubiquinol--cytochrome-c reductase iron-sulfur protein precursor YEL039C CYC7 cytochrome-c isoform 2 YEL053C MAK10 glucose-repressible protein YER061C CEM1 beta-keto-acyl-ACP synthase, mitochondrial YER141W COX15 cytochrome oxidase assembly factor YER154W OXA1 cytochrome oxidase biogenesis protein YFR033C QCR6 ubiquinol--cytochrome-c reductase 17K protein YGL018C JAC1 molecular chaperone YGL119W ABC1 ubiquinol--cytochrome-c reductase complex assembly protein YGL187C COX4 cytochrome-c oxidase chain IV YGL191W COX13 cytochrome-c oxidase chain VIa YGL226W YGL226W similarity to N.crassa cytochrome-c oxidase chain V YGR008C STF2 ATPase stabilizing factor YGR062C COX18 required for activity of mitochondrial cytochrome oxidase YGR112W SHY1 SURF homologue protein YGR174C CBP4 ubiquinol--cytochrome-c reductase assembly factor YGR183C QCR9 ubiquinol--cytochrome-c reductase subunit 9 YGR207C ETF-BETA electron-transferring flavoprotein, beta chain YHR001W-A QCR10 ubiquinol--cytochrome-c reductase 8.5 kDa subunit YHR051W COX6 cytochrome-c oxidase subunit VI YIL043C CBR1 cytochrome-b5 reductase YIL111W COX5B cytochrome-c oxidase chain Vb YJL166W QCR8 ubiquinol--cytochrome-c reductase chain VIII YJR034W PET191 involved in assembly of cytochrome oxidase YJR048W CYC1 cytochrome-c isoform 1 YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL055C OAR1 putative 3-oxoacyl-(acyl carrier protein) reductase YKL141W SDH3 cytochrome b560 subunit of respiratory complex II YKL150W MCR1 cytochrome-b5 reductase YKR016W YKR016W weak similarity to mysoin heavy chain proteins YKR046C YKR046C hypothetical protein YLL009C COX17 interacts genetically with SCO1 and SCO2 in cytochrome oxidase assembly YLR038C COX12 cytochrome-c oxidase, subunit VIB YLR044C PDC1 pyruvate decarboxylase, isozyme 1 YLR248W RCK2 Ca/calmodulin-dependent ser/thr protein kinase YLR295C ATP14 F1F0-ATPase complex, subunit h YLR395C COX8 cytochrome-c oxidase chain VIII YML054C CYB2 lactate dehydrogenase cytochrome b2 YML081C-A ATP18 gene for subunit i/j of the mitochondrial F1F0-ATP synthase YML087C YML087C strong similarity to YML125c, similarity to cytochrome-b5- and nitrate reductases YML120C NDI1 NADH-ubiquinone-6 oxidoreductase YML125C YML125C strong similarity to cytochrome-b5- and nitrate reductases YML129C COX14 cytochrome-c oxidase assembly protein YMR073C YMR073C weak similarity to C-terminal part of cytochrome b5 and b2 YMR089C YTA12 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YMR145C NDH1 mitochondrial cytosolically directed NADH dehydrogenase YMR165C SMP2 involved in plasmid maintenance, respiration and cell proliferation YMR244W YMR244W similarity to UTH1P, NCA3P, YIL123w and SUN4P YMR256C COX7 cytochrome-c oxidase, subunit VII YMR282C AEP2 required for the expression of subunit-9 of atp synthase YNL052W COX5A cytochrome-c oxidase chain V.A precursor YNL118C DCP2 suppressor protein of a yeast pet mutant YNL237W YTP1 weak similarity to mitochondrial electron transport proteins YOL077W-A ATP19 subunit K of the dimeric form of mitochondrial F1F0-ATP synthase YOR065W CYT1 cytochrome-c1 YOR221C MCT1 malonyl-CoA:ACP transferase YOR356W YOR356W strong similarity to human electron transfer flavoprotein-ubiquinone oxidoreductase YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPR004C YPR004C strong similarity to electron transfer flavoproteins alpha chain YPR020W ATP20 subunit G of the dimeric form of mitochondrial F1F0-ATP Synthase YPR048W TAH18 similarity to M.domestica NADPH--ferrihemoprotein reductase and mammalian nitric-oxide synthases YPR191W QCR2 ubiquinol--cytochrome-c reductase 40KD chain II Q0045 COX1 cytochrome-c oxidase subunit I Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0105 COB ubiquinol-cytochrome-c reductase subunit (cytochrome B) Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 Q0250 COX2 cytochrome-c oxidase subunit II Q0275 COX3 cytochrome-c oxidase chain III fermentation (33 ORFs) 02.16 33 YAL061W FUN50 similarity to alcohol/sorbitol dehydrogenase YBR145W ADH5 alcohol dehydrogenase V YCR105W YCR105W strong similarity to alcohol dehydrogenases YCR107W AAD3 strong similarity aryl-alcohol reductases of P. chrysosporium YDL174C DLD1 D-lactate ferricytochrome C oxidoreductase (D-LCR) YDL243C AAD4 strong similarity to aryl-alcohol dehydrogenase YDR081C PDC2 pyruvate decarboxylase regulatory protein YDR380W ARO10 similarity to PDC6P, THI3P and to pyruvate decarboxylases YER073W ALD5 aldehyde dehydrogenase (NAD+), mitochondrial YFL056C AAD6 strong similarity to aryl-alcohol dehydrogenases YFL057C YFL057C strong similarity to aryl-alcohol dehydrogenases YGL256W ADH4 alcohol dehydrogenase IV YGR087C PDC6 pyruvate decarboxylase 3 YHL008C YHL008C similarity to M.formicicum formate dehydrogenase YHR039C MSC7 similarity to aldehyde dehydrogenases YJR155W AAD10 strong similarity to aryl-alcohol dehydrogenase YKR096W YKR096W similarity to mitochondrial aldehyde dehydrogenase Ald1p YLR044C PDC1 pyruvate decarboxylase, isozyme 1 YLR134W PDC5 pyruvate decarboxylase, isozyme 2 YMR116C ASC1 40S small subunit ribosomal protein YMR169C ALD3 stress inducible aldehyde dehydrogenase YMR285C NGL2 similarity to CCR4P YMR303C ADH2 alcohol dehydrogenase II YMR318C YMR318C strong similarity to alcohol-dehydrogenase YNL331C AAD14 strong similarity aryl-alcohol reductase YOL086C ADH1 alcohol dehydrogenase I YOL165C AAD15 putative aryl alcohol dehydrogenase YOR126C IAH1 isoamyl acetate hydrolytic enzyme YOR388C FDH1 strong similarity to H.polymorpha formate dehydrogenase YPL061W ALD6 aldehyde dehydrogenase, cytosolic YPL088W YPL088W similarity to aryl-alcohol dehydrogenases YPL275W YPL275W identical to a region of YOR388c YPL276W YPL276W identical to a region of YOR388c metabolism of energy reserves (glycogen, trehalose) (37 ORFs) 02.19 37 YBL058W SHP1 potential regulatory subunit for GLC7P YBR001C NTH2 alpha,alpha-trehalase YBR126C TPS1 alpha,alpha-trehalose-phosphate synthase, 56 KD subunit YBR229C ROT2 glucosidase II, catalytic subunit YBR299W MAL32 alpha-glucosidase YDR001C NTH1 neutral trehalase (alpha,alpha-trehalase) YDR074W TPS2 alpha,alpha-trehalose-phosphate synthase, 102 KD subunit YEL011W GLC3 1,4-glucan branching enzyme (glycogen branching enzyme) YER054C GIP2 GLC7P-interacting protein YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YFR015C GSY1 UDP glucose--starch glucosyltransferase, isoform 1 YGL134W PCL10 cyclin like protein interacting with PHO85P YHR047C AAP1' alanine/arginine aminopeptidase YIL045W PIG2 Protein Interacting with GSY2P YIL172C YIL172C identical to FSP2P and similarity to other alpha-glucosidases YJL137C GLG2 self-glucosylating initiator of glycogen synthesis YJL216C YJL216C strong similarity to Mal62p YJL221C FSP2 strong similarity to alpha-D-glucosidase YKL035W UGP1 UTP--glucose-1-phosphate uridylyltransferase YKL127W PGM1 phosphoglucomutase, minor isoform YKL128C PMU1 high copy suppressor of ts TPS2 mutant phenotype YKR058W GLG1 self-glycosylating initiator of glycogen synthesis YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR258W GSY2 UDP-glucose--starch glucosyltransferase, isoform 2 YLR273C PIG1 putative type 1 phosphatase regulatory subunit YML100W TSL1 alpha,alpha-trehalose-phosphate synthase, 123 KD subunit YMR105C PGM2 phosphoglucomutase, major isoform YMR261C TPS3 alpha,alpha-trehalose-phosphate synthase, 115 KD subunit YNR032W PPG1 phosphoprotein phosphatase PPG catalytic chain YOL157C YOL157C strong similarity to alpha-glucosidases YOR178C GAC1 ser/thr phosphoprotein phosphatase 1, regulatory chain YPL031C PHO85 cyclin-dependent protein kinase YPL219W PCL8 cyclin like protein interacting with PHO85P YPL240C HSP82 heat shock protein YPR026W ATH1 acid trehalase, vacuolar YPR160W GPH1 glycogen phosphorylase YPR184W GDB1 similarity to human 4-alpha-glucanotransferase (EC 2.4.1.25)/amylo-1,6-glucosidase (EC 3.2.1.33) glyoxylate cycle (6 ORFs) 02.22 6 YCR005C CIT2 citrate (si)-synthase, peroxisomal YER065C ICL1 isocitrate lyase YLR304C ACO1 aconitate hydratase YNL117W MLS1 malate synthase 1 YOL126C MDH2 malate dehydrogenase, cytoplasmic YPR006C ICL2 non-functional isocitrate lyase oxidation of fatty acids (7 ORFs) 02.25 7 YGL205W POX1 acyl-CoA oxidase YGR207C ETF-BETA electron-transferring flavoprotein, beta chain YIL160C POT1 acetyl-CoA C-acyltransferase, peroxisomal YKR009C FOX2 hydratase-dehydrogenase-epimerase, peroxisomal YLR284C ECI1 delta3-cis-delta2-trans-enoyl-CoA isomerase YNL202W SPS19 peroxisomal 2,4-dienoyl-CoA reductase YOR356W YOR356W strong similarity to human electron transfer flavoprotein-ubiquinone oxidoreductase other energy generation activities (16 ORFs) 02.99 16 YAL054C ACS1 acetyl-CoA synthetase YDL078C MDH3 malate dehydrogenase, peroxisomal YDL181W INH1 inhibitor of mitochondrial ATPase YDR384C YDR384C strong similarity to Y.lipolytica GPR1 gene YEL020C YEL020C similarity to O.formigenes oxalyl-CoA decarboxylase YEL071W DLD3 D-lactate dehydrogenase YHR076W YHR076W weak similarity to C.elegans hypothetical protein CEW09D10 YHR179W OYE2 NADPH dehydrogenase (old yellow enzyme), isoform 1 YIR031C DAL7 malate synthase 2 YLR153C ACS2 acetyl-coenzyme A synthetase YML035C AMD1 AMP deaminase YMR170C ALD2 aldehyde dehydrogenase 2 (NAD+) YMR267W PPA2 inorganic pyrophosphatase, mitochondrial YNL009W IDP3 isocitrate dehydrogenase, NADP-dependent YOL079W YOL079W similarity to NADH dehydrogenases YPL171C OYE3 NAPDH dehydrogenase (old yellow enzyme), isoform 3 CELL CYCLE AND DNA PROCESSING (628 ORFs) 03 628 YAL009W SPO7 meiotic protein YAL015C NTG1 DNA repair protein YAL016W TPD3 ser/thr protein phosphatase 2A, regulatory chain A YAL019W FUN30 similarity to helicases of the SNF2/RAD54 family YAL024C LTE1 GDP/GTP exchange factor YAL025C MAK16 nuclear viral propagation protein YAL029C MYO4 myosin heavy chain, unconventional (class V) isoform YAL033W POP5 required for processing of tRNAs and rRNAs YAL034W-A MTW1 determining metaphase spindle length YAL040C CLN3 cyclin, G1/S-specific YAL041W CDC24 GTP/GDP exchange factor for CDC42P YAL047C SPC72 STU2P Interactant YAR003W SWD1 similarity to human RB protein binding protein YAR007C RFA1 DNA replication factor A, 69 KD subunit YAR019C CDC15 protein kinase of the MAP kinase kinase kinase family YAR044W OSH1 similarity to human oxysterol binding protein (OSBP) YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBL019W APN2 AP endonuclease, exonuclease III homolog YBL020W RFT1 nuclear division protein YBL023C MCM2 member of the MCM2P,MCM3P,CDC46P family YBL035C POL12 DNA-directed DNA polymerase alpha, 70 KD subunit YBL058W SHP1 potential regulatory subunit for GLC7P YBL063W KIP1 kinesin-related protein YBL079W NUP170 nuclear pore protein YBL084C CDC27 subunit of anaphase-promoting complex (cyclosome) YBL088C TEL1 telomere length control protein YBL097W BRN1 functional homologue of human BRRN1 YBL105C PKC1 ser/thr protein kinase YBR045C GIP1 GLC7-interacting protein YBR057C MUM2 meiotic protein YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR073W RDH54 required for mitotic diploid-specific recombination and repair and meiosis YBR078W ECM33 involved in cell wall biogenesis and architecture YBR079C RPG1 translation initiation factor eIF3 (p110 subunit) YBR087W RFC5 DNA replication factor C, 40 KD subunit YBR088C POL30 Proliferating Cell Nuclear Antigen (PCNA) YBR098W MMS4 putative transcriptional (co)activator for DNA damage YBR107C IML3 weak similarity to N.crassa chitin synthase YBR109C CMD1 calmodulin YBR114W RAD16 nucleotide excision repair protein YBR133C HSL7 adapter in a regulatory pathway that relieves tyrosine phosphorylation of CDC28 YBR135W CKS1 cyclin-dependent kinases regulatory subunit YBR136W MEC1 cell cycle checkpoint protein YBR138C HDR1 High-Dosage Reductional segregation defective YBR156C SLI15 Mitotic spindle protein involved in chromosome segregation YBR160W CDC28 cyclin-dependent protein kinase YBR186W PCH2 putative ATPase YBR195C MSI1 chromatin assembly complex, subunit p50 YBR200W BEM1 bud emergence mediator YBR202W CDC47 cell division control protein YBR211C AME1 actin related protein YBR215W HPC2 cell cycle regulatory protein YBR238C YBR238C strong similarity to general chromatin factor SPT16P YBR243C ALG7 UDP-N-acetylglucosamine-1-phosphate transferase YBR272C HSM3 mismatch repair protein YBR274W CHK1 regulats inhibitory Cdk phosphorylation of PDS1 YBR276C PPS1 protein tyrosine phosphatase YBR278W DPB3 DNA-directed DNA polymerase epsilon, subunit C YCL004W PGS1 phosphatidylglycerophosphate synthase YCL016C DCC1 part of an alternative RFC complex YCL024W KCC4 kinase coordinate cell cycle progression with the organization of the peripheralcytoskeleton YCL029C BIK1 nuclear fusion protein YCL048W YCL048W strong similarity to sporulation-specific protein SPS2P YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCR002C CDC10 cell division control protein YCR014C POL4 DNA polymerase YCR028C-A RIM1 ssDNA-binding protein, mitochondrial YCR052W RSC6 subunit of the RSC complex YCR057C PWP2 periodic tryptophan protein YCR066W RAD18 DNA repair protein YCR077C PAT1 topoisomerase II-associated protein YCR086W CSM1 involved in nuclear migration YCR092C MSH3 DNA mismatch repair protein YCR094W CDC50 cell division cycle mutant YDL003W MCD1 Mitotic Chromosome Determinant YDL008W APC11 subunit of the anaphase promoting complex YDL017W CDC7 protein kinase YDL028C MPS1 serine/threonine/tyrosine protein kinase YDL029W ARP2 actin-like protein YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL047W SIT4 ser/thr protein phosphatase YDL056W MBP1 transcription factor, subunit of the MBF factor YDL059C RAD59 recombination and DNA repair protein YDL064W UBC9 E2 ubiquitin-conjugating enzyme YDL088C ASM4 component of the karyopherin docking complex of the nuclear pore complex YDL101C DUN1 protein kinase YDL102W CDC2 DNA-directed DNA polymerase delta, catalytic 125 KD subunit YDL108W KIN28 cyclin-dependent ser/thr protein kinase YDL114W YDL114W weak similarity to Rhizobium nodulation protein nodG YDL126C CDC48 microsomal protein of CDC48/PAS1/SEC18 family of ATPases YDL127W PCL2 cyclin, G1/S-specific YDL132W CDC53 controls G1/S transition YDL134C PPH21 protein ser/thr phosphatase PP2A-1 YDL154W MSH5 meiosis-specific protein YDL155W CLB3 cyclin, G2/M-specific YDL164C CDC9 DNA ligase YDL165W CDC36 transcription factor YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL200C MGT1 O6-methylguanine DNA repair methyltransferase YDL220C CDC13 cell division control protein YDL225W SHS1 septin YDL226C GCS1 ADP-ribosylation factor GTPase-activating protein (ARF-GAP) YDR004W RAD57 DNA repair protein YDR022C CIS1 involved in suppression of CIK1 mutation YDR030C RAD28 protein involved in the same pathway as RAD26P, has beta-transducin (WD-40) repeats YDR052C DBF4 regulatory subunit for CDC7P protein kinase YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR055W PST1 strong similarity to SPS2 protein YDR061W YDR061W similarity to E.coli modF and photorepair protein phrA YDR076W RAD55 DNA repair protein YDR082W STN1 involved in telomere length regulation YDR096W GIS1 DNA damage-responsive repressor of PHR1 YDR097C MSH6 DNA mismatch repair protein YDR099W BMH2 suppressor of clathrin deficiency YDR108W GSG1 sporulation specific protein YDR110W FOB1 DNA replication fork blocking protein YDR113C PDS1 cell cycle regulator YDR118W APC4 subunit of the anaphase promoting complex YDR130C FIN1 weak similarity to sea urchin myosin heavy chain YDR137W RGP1 reduced growth phenotype protein YDR138W HPR1 hyperrecombination protein related to TOP1P YDR150W NUM1 nuclear migration protein YDR168W CDC37 cell division control protein YDR172W SUP35 eukaryotic peptide chain release factor GTP-binding subunit YDR180W SCC2 involved in sister chromatid cohesion YDR182W CDC1 cell division control protein YDR190C RVB1 RUVB-like protein YDR206W EBS1 similarity to EST1 protein YDR207C UME6 negative transcriptional regulator YDR217C RAD9 DNA repair checkpoint protein YDR218C SPR28 septin-related sporulation protein YDR227W SIR4 silencing regulatory and DNA-repair protein YDR254W CHL4 chromosome segregation protein YDR260C SWM1 developmentally regulated gene, is required for spore wall assembly YDR284C DPP1 diacylglycerol pyrophosphate phosphatase YDR285W ZIP1 synaptonemal complex protein YDR293C SSD1 involved in the tolerance to high concentration of Ca2+ YDR296W MHR1 Involved in mitochondrial homologous DNA recombination YDR311W TFB1 TFIIH subunit (transcription initiation factor), 75 kD YDR325W YCG1 Yeast Condensin G YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR356W NUF1 spindle pole body component YDR363W-A SEM1 regulator of exocytosis and pseudohyphal differentiation YDR364C CDC40 cell division control protein YDR369C XRS2 DNA repair protein YDR386W MUS81 involved in the repair of UV and methylation induced DNA damage YDR416W SYF1 synthetic lethal with CDC40 YDR419W RAD30 DNA repair protein YDR440W DOT1 putative ATPase YDR457W TOM1 E3 ubiqitin ligase required for G2/M transition YDR460W TFB3 TFIIH subunit (transcription/repair factor) YDR488C PAC11 required in the absence of CIN8P YDR499W LCD1 cell cycle checkpoint protein YDR507C GIN4 ser/thr protein kinase YDR522C SPS2 sporulation-specific protein YDR523C SPS1 ser/thr protein kinase YDR545W YRF1-1 Y'-helicase protein 1 YEL019C MMS21 DNA repair protein YEL032W MCM3 replication initiation protein YEL037C RAD23 nucleotide excision repair protein (ubiquitin-like protein) YEL061C CIN8 kinesin-related protein YEL066W HPA3 histone and other protein acetyltransferase YER007W PAC2 involved in the stabilization of microtubles YER016W BIM1 binding to microtubules YER044C-A MEI4 meiosis-specific protein YER066W YER066W strong similarity to cell division control protein CDC4P YER070W RNR1 ribonucleoside-diphosphate reductase, large subunit YER075C PTP3 protein tyrosine phosphatase YER095W RAD51 DNA repair protein YER111C SWI4 transcription factor YER122C GLO3 zinc finger protein YER123W YCK3 casein kinase, isoform 3 YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER142C MAG1 3-methyladenine DNA glycosylase YER155C BEM2 GTPase-activating protein YER162C RAD4 excision repair protein YER171W RAD3 DNA helicase/ATPase YER173W RAD24 cell cycle checkpoint protein YER176W ECM32 DNA dependent ATPase/DNA helicase B YER177W BMH1 14-3-3 protein involved in rapamycin-sensitive signalling YER179W DMC1 meiosis-specific protein YER180C ISC10 meiosis-specific protein YER190W YRF1-2 Y'-helicase protein 1 YFL003C MSH4 meiosis-specific protein YFL008W SMC1 chromosome segregation protein YFL009W CDC4 cell division control protein YFL014W HSP12 heat shock protein YFL017C GNA1 essential acetyltransferase YFL029C CAK1 cdk-activating protein kinase YFL034C-B MOB2 required for maintenance in ploidy YFL036W RPO41 DNA-directed RNA polymerase, mitochondrial YFL037W TUB2 beta-tubulin YFL039C ACT1 actin YFR023W PES4 DNA-directed DNA polymerase epsilon suppressor YFR027W ECO1 involved in sister chromatid cohesion during replication YFR028C CDC14 dual specificity phosphatase YFR031C SMC2 chromosome segregation protein YFR036W CDC26 subunit of anaphase-promoting complex (cyclosome) YFR037C RSC8 subunit of the RSC complex YFR038W YFR038W strong similarity to mouse lymphocyte specific helicase YFR040W SAP155 SIT4P-associated protein YFR052W RPN12 26S proteasome regulatory subunit YGL003C CDH1 substrate-specific activator of APC-dependent proteolysis YGL025C PGD1 mediator complex subunit YGL033W HOP2 required for pairing of homologous chromosomes YGL043W DST1 TFIIS (transcription elongation factor) YGL048C RPT6 26S proteasome regulatory subunit YGL056C SDS23 strong similarity to pombe SDS23 YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL061C DUO1 essential mitotic spindle protein YGL073W HSF1 heat shock transcription factor YGL075C MPS2 Protein of the nuclear envelope/endoplasmic reticulum required for spindle pole body assembly and normal chromosome segregation YGL086W MAD1 spindle assembly checkpoint protein YGL087C MMS2 part of the error-free postreplication repair pathway YGL090W LIF1 DNA ligase IV interacting factor YGL106W MLC1 MYO2P light chain YGL116W CDC20 cell division control protein YGL127C SOH1 allows HPR1 null mutant to grow at 37 deg. YGL155W CDC43 geranylgeranyltransferase beta subunit YGL158W RCK1 ser/thr protein kinase YGL163C RAD54 DNA-dependent ATPase of the SNF2P family YGL173C KEM1 multifunctional nuclease YGL175C SAE2 meiotic recombination protein YGL178W MPT5 multicopy suppressor of POP2 YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL190C CDC55 ser/thr phosphatase 2A regulatory subunit B YGL194C HOS2 putative histone deacetylase YGL201C MCM6 involved in replication YGL207W SPT16 general chromatin factor YGL213C SKI8 antiviral protein of the beta-transducin (WD-40) repeat family YGL215W CLG1 cyclin-like protein YGL216W KIP3 kinesin-related protein required for nuclear migration YGL229C SAP4 SIT4P-associated protein YGL240W DOC1 component of the anaphase promoting complex YGL249W ZIP2 required for meiotic recombination and disjunction YGR023W MTL1 potential cell wall stres sensor YGR029W ERV1 mitochondrial biogenesis and regulation of cell cycle YGR044C RME1 zinc-finger transcription factor YGR049W SCM4 CDC4 suppressor YGR056W RSC1 member of RSC complex, which remodels the structure of chromatin YGR063C SPT4 transcription elongation protein YGR078C PAC10 GIM4 - Gim complex component YGR092W DBF2 ser/thr protein kinase related to DBF20P YGR098C ESP1 required for sister chromatid separation YGR108W CLB1 cyclin, G2/M-specific YGR109C CLB6 cyclin, B-type YGR113W DAM1 essential mitotic spindle pole protein YGR116W SPT6 transcription elongation protein YGR132C PHB1 prohibitin, antiproliferative protein YGR140W CBF2 kinetochore protein complex CBF3, 110 KD subunit YGR144W THI4 involved in thiamine biosynthesis and DNA repair YGR179C OKP1 component of centromere/kinetochore-associated protein network YGR180C RNR4 ribonucleotide reductase small subunit YGR188C BUB1 ser/thr protein kinase YGR209C TRX2 thioredoxin II YGR230W BNS1 Bypasses Need for SPO12P YGR231C PHB2 Prohibitin YGR245C SDA1 required for normal organization of the actin cytoskeleton; required for passage through Start YGR252W GCN5 histone acetyltransferase YGR253C PUP2 20S proteasome subunit(alpha5) YGR258C RAD2 structure-specific nuclease of the nucleotide excision repairosome YGR274C TAF145 TFIID subunit (TBP-associated factor), 145 kD YHL022C SPO11 catalytic subunit of the meiotic double strand break transesterase YHL024W RIM4 No sporulation YHL027W RIM101 meiotic regulatory protein YHR004C NEM1 required for nuclear morphology YHR013C ARD1 protein N-acetyltransferase subunit YHR014W SPO13 meiosis-specific protein YHR023W MYO1 myosin-1 isoform (type II myosin) heavy chain YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR031C RRM3 DNA helicase involved in rDNA replication and Ty1 transposition YHR079C-A SAE3 meiosis specific protein YHR086W NAM8 meiotic recombination protein YHR101C BIG1 big cells phenotype YHR102W KIC1 ser/thr protein kinase that interacts with CDC31P YHR107C CDC12 septin YHR118C ORC6 origin recognition complex, 50 KD subunit YHR119W SET1 involved in chromatin-mediated gene regulation YHR120W MSH1 DNA mismatch repair protein, mitochondrial YHR124W NDT80 meiosis-specific protein YHR129C ARP1 centractin YHR135C YCK1 casein kinase I isoform YHR152W SPO12 sporulation protein YHR153C SPO16 sporulation protein YHR157W REC104 meiosis-specific protein YHR164C DNA2 DNA helicase YHR165C PRP8 U5 snRNP protein, pre-mRNA splicing factor YHR166C CDC23 subunit of anaphase-promoting complex (cyclosome) YHR172W SPC97 spindle pole body component YHR184W SSP1 essential for meiosis and spore formation YHR205W SCH9 serine/threonine protein kinase involved in stress response and nutrient-sensing signaling pathway YHR206W SKN7 transcription factor with similarity to HSF1P YHR208W BAT1 branched chain amino acid aminotransferase, mitochondrial YIL009C-A EST3 subunit of the telomerase YIL026C IRR1 essential protein YIL031W ULP2 SMT3P-specific protease, degrades conjugated ubiquitin-like protein SMT3P YIL035C CKA1 casein kinase II, catalytic alpha chain YIL036W CST6 ATF/CREB activator YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL066C RNR3 ribonucleotide reductase, repair inducible large subunit YIL072W HOP1 meiosis-specific protein YIL095W PRK1 serine/threonine protein kinase involved in regulation of actin cytoskeleton organization YIL106W MOB1 required for completion of mitosis and maintenance of ploidy YIL123W SIM1 involved in cell cycle regulation and aging YIL126W STH1 subunit of the RSC complex YIL128W MET18 involved in NER repair and RNA polymerase II transcription YIL139C REV7 DNA polymerase zeta subunit YIL143C SSL2 DNA helicase YIL150C DNA43 required for S-phase initiation or completion YIL153W RRD1 strong similarity to human phosphotyrosyl phosphatase activator YIR002C MPH1 protection of the genome from spontaneous and chemically induced damage YIR008C PRI1 DNA-directed DNA polymerase alpha 48kDa subunit (DNA primase) YIR024C GIF1 G1 Factor needed for normal G1 phase YIR026C YVH1 protein tyrosine phosphatase YIR033W MGA2 may be involved in the remodeling chromatin structure YJL005W CYR1 adenylate cyclase YJL013C MAD3 spindle-assembly checkpoint protein YJL026W RNR2 ribonucleoside-diphosphate reductase, small subunit YJL030W MAD2 spindle-assembly checkpoint protein YJL034W KAR2 nuclear fusion protein YJL065C YJL065C weak similarity to DNA-directed DNA polymerase II chain C YJL074C SMC3 required for structural maintenance of chromosomes YJL080C SCP160 required for maintenance of exact ploidy YJL090C DPB11 involved in DNA replication and S-phase checkpoint YJL092W HPR5 ATP-dependent DNA helicase YJL095W BCK1 ser/thr protein kinase of the MEKK family YJL098W SAP185 SIT4P-associating protein YJL106W IME2 ser/thr protein kinase YJL141C YAK1 ser/thr protein kinase YJL146W IDS2 IME2-dependent signaling protein YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJL173C RFA3 DNA replication factor A, 13 KD subunit YJL187C SWE1 ser/tyr dual-specifity protein kinase YJL194W CDC6 cell division control protein YJR006W HYS2 DNA-directed DNA polymerase delta, 55 KD subunit YJR021C REC107 meiotic recombination protein YJR035W RAD26 DNA repair and recombination protein YJR043C POL32 polymerase-associated gene, third (55 kDa) subunit of DNA polymerase delta YJR046W TAH11 weak similarity to Xenopus vimentin 4 YJR052W RAD7 nucleotide excision repair protein YJR053W BFA1 spindle assembly checkpoint protein YJR060W CBF1 kinetochore protein YJR066W TOR1 phosphatidylinositol 3-kinase YJR068W RFC2 DNA replication factor C, 41 KD subunit YJR076C CDC11 septin YJR089W BIR1 member of the inhibitor of apoptosis family, participate in chromosome segregation events YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR091C JSN1 suppresses the high-temperature lethality of TUB2-150 YJR094C IME1 transcription factor required for sporulation YJR112W NNF1 nuclear envelope protein YJR135C MCM22 required for maintenance of chromosomes and minichromosomes YJR138W IML1 similarity to C.elegans hypothetical protein T08A11.1 YJR140C HIR3 involved in cell cycle regulation of histone transcription YJR144W MGM101 mitochondrial genome maintenance protein YKL011C CCE1 cruciform-cutting endonuclease, mitochondrial YKL017C HCS1 DNA helicase A YKL020C SPT23 dosage-dependent suppressor of Ty-induced promotor mutations YKL022C CDC16 subunit of anaphase-promoting complex (cyclosome) YKL042W SPC42 spindle pole body component YKL045W PRI2 DNA-directed DNA polymerase alpha , 58 KD subunit (DNA primase) YKL048C ELM1 ser/thr-specific protein kinase YKL049C CSE4 component of the core centromere YKL089W MIF2 required for normal chromosome segregation and spindle integrity YKL101W HSL1 ser/thr protein kinase, coupling septin ring assembly to cell cycle progression YKL108W SLD2 chromosomal DNA replication protein YKL112W ABF1 ARS-binding factor YKL113C RAD27 ssDNA endonuclease and 5'-3'exonuclease YKL114C APN1 AP endonuclease YKL145W RPT1 26S proteasome regulatory subunit YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL179C YKL179C similarity to NUF1P YKL193C SDS22 regulatory subunit for the mitotic function of type I protein phosphatase YKL203C TOR2 phosphatidylinositol 3-kinase YKR008W RSC4 member of RSC complex, which remodels the structure of chromatin YKR028W SAP190 SIT4P-associated protein YKR031C SPO14 phospholipase D YKR042W UTH1 involved in the aging process YKR046C YKR046C hypothetical protein YKR048C NAP1 nucleosome assembly protein I YKR054C DYN1 dynein heavy chain, cytosolic YKR063C LAS1 involved in cell morphogenesis, cytoskeletal regulation and bud formation YKR072C SIS2 involved in cell cycle-specific gene expression YKR095W MLP1 myosin-like protein related to USO1P YLL003W SFI1 similarity to Xenopus laevis XCAP-C YLL004W ORC3 origin recognition complex, 62 kDa subunit YLL016W SDC25 GDP/GTP exchange factor (GEF) YLL017W YLL017W maybe part of SCD25 YLR005W SSL1 TFIIH subunit (transcription initiation factor), factor B YLR010C TEN1 involved in telomere length regulation and telomere end protection YLR032W RAD5 DNA helicase YLR035C MLH2 similarity to human mutL protein homolog, mouse PMS2, MLH1P and PMS1P YLR043C TRX1 thioredoxin I YLR075W RPL10 60S large subunit ribosomal protein YLR079W SIC1 p40 inhibitor of CDC28P-Clb protein kinase complex YLR102C APC9 subunit of the Anaphase Promoting Complex YLR103C CDC45 required for minichromosome maintenance and initiation of chromosomal DNA replication YLR117C CLF1 strong similarity to Drosophila putative cell cycle control protein crn YLR127C APC2 component of the anaphase promoting complex YLR129W DIP2 DOM34P-interacting protein YLR131C ACE2 metallothionein expression activator YLR175W CBF5 putative rRNA pseuduridine synthase YLR178C TFS1 CDC25-dependent nutrient- and ammonia-response cell-cycle regulator YLR179C YLR179C similarity to TFS1P YLR182W SWI6 transcription factor YLR210W CLB4 cyclin, G2/M-specific YLR212C TUB4 gamma tubulin YLR215C CDC123 strong similarity to rat cell cycle progression related D123 protein YLR226W BUR2 divergent CDK-cyclin complex YLR229C CDC42 GTP-binding protein of RAS superfamily YLR233C EST1 telomere elongation protein YLR234W TOP3 DNA topoisomerase III YLR248W RCK2 Ca/calmodulin-dependent ser/thr protein kinase YLR263W RED1 meiosis-specific protein YLR274W CDC46 cell division control protein YLR286C CTS1 endochitinase YLR288C MEC3 G2-specific checkpoint protein YLR299W ECM38 gamma-glutamyltransferase, involved in glutathione synthesis YLR305C STT4 phosphatidylinositol-4-kinase YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR314C CDC3 cell division control protein YLR318W EST2 catalytic subunit of the telomerase YLR321C SFH1 subunit of the RSC complex YLR329W REC102 meiotic recombination protein YLR332W MID2 mating process protein YLR356W YLR356W similarity to SCM4 protein YLR357W RSC2 member of RSC complex, which remodels the structure of chromatin YLR369W SSQ1 mitochondrial heat shock protein 70 YLR383W RHC18 recombination repair protein YLR394W CST9 protein required for synapsis, meiotic recombination, sporulation, proper chromosome segregation, and synaptonemal complex formation YLR403W SFP1 zinc finger protein YLR442C SIR3 silencing regulatory and DNA-repair protein YLR466W YRF1-4 protein with similarity to other subtelomerically-coded Y'-helicase proteins YML010W SPT5 transcription elongation protein YML021C UNG1 uracil-DNA glycosylase YML031W NDC1 nuclear envelope protein YML032C RAD52 recombination and DNA repair protein YML058W SML1 protein inhibitor of ribonucleotide reductase YML058W-A HUG1 hydroxyurea and UV and gamma radiation induced YML060W OGG1 8-oxoguanine DNA glycosylase YML061C PIF1 DNA helicase involved in mitochondrial DNA repair and telomere length YML064C TEM1 GTP-binding protein of the RAS superfamily YML065W ORC1 origin recognition complex, 104 KD subunit YML069W POB3 protein that binds to DNA polymerase I (PolI) YML085C TUB1 alpha-1 tubulin YML095C RAD10 DNA repair protein YML102W CAC2 chromatin assembly complex, subunit p60 YML104C MDM1 intermediate filament protein YML109W ZDS2 multicopy suppressor of SIN4 YML115C VAN1 vanadate resistance protein YML124C TUB3 alpha-3 tubulin YMR001C CDC5 involved in regulation of DNA replication YMR028W TAP42 component of the Tor signaling pathway YMR032W HOF1 involved in cytokinesis YMR035W IMP2 mitochondrial inner membrane protease subunit YMR036C MIH1 M-phase inducing protein tyrosine phosphatase YMR043W MCM1 transcription factor of the MADS box family YMR052W FAR3 involved in pheromone-mediated cell cycle arrest YMR055C BUB2 cell cycle arrest protein YMR072W ABF2 high mobility group protein YMR076C PDS5 precocious dissociation of sister chromatids YMR078C CTF18 required for accurate chromosome transmission in mitosis and maintenance of normal telomere length YMR094W CTF13 kinetochore protein complex, CBF3, 58 KD subunit YMR096W SNZ1 stationary phase protein YMR104C YPK2 ser/thr protein kinase YMR106C YKU80 component of DNA end-joining repair pathway YMR127C SAS2 involved in silencing at HMR YMR133W REC114 meiotic recombination protein YMR137C PSO2 DNA repair protein YMR138W CIN4 GTP-binding protein YMR139W RIM11 ser/thr protein kinase YMR167W MLH1 DNA mismatch repair protein YMR168C CEP3 kinetochore protein complex, 71 KD subunit YMR190C SGS1 DNA helicase YMR198W CIK1 spindle pole body associated protein YMR199W CLN1 cyclin, G1/S-specific YMR200W ROT1 mutant suppresses TOR2 mutation YMR201C RAD14 nucleotide excision repair protein YMR213W CEF1 required during G2/M transition YMR224C MRE11 DNA repair and meiotic recombination protein YMR228W MTF1 RNA polymerase specific factor, mitochondrial YMR241W YHM2 yeast suppressor gene of HM (mitochondrial histone) mutant (ABF2) YMR262W YMR262W similarity to S.pombe scn1 protein YMR273C ZDS1 involved in negative regulation of cell polarity YMR276W DSK2 ubiquitin-like protein YMR284W YKU70 high-affinity DNA-binding protein YMR290C HAS1 helicase associated with SET1P YMR294W JNM1 mitosis protein, involved in nuclear migration YNL001W DOM34 functions in protein translation to promote G1 progression and differentiation YNL007C SIS1 heat shock protein YNL012W SPO1 transcriptional regulator involved in sporulation YNL021W HDA1 histone deacetylase A YNL025C SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YNL053W MSG5 dual-specifity protein phosphatase YNL064C YDJ1 mitochondrial and ER import protein YNL082W PMS1 DNA mismatch repair protein YNL088W TOP2 DNA topoisomerase II (ATP-hydrolysing) YNL098C RAS2 GTP-binding protein YNL102W POL1 DNA-directed DNA polymerase alpha, 180 KD subunit YNL126W SPC98 spindle pole body component YNL153C GIM3 Gim complex component YNL154C YCK2 casein kinase I isoform YNL172W APC1 subunit of anaphase-promoting complex (cyclosome) YNL188W KAR1 cell division control protein YNL192W CHS1 chitin synthase I YNL196C SLZ1 sporulation-specific protein YNL204C SPS18 sporulation-specific zinc-finger protein YNL210W MER1 meiotic recombination protein YNL213C YNL213C similarity to hypothetical protein Neurospora crassa YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL218W MGS1 similarity to E.coli hypothetical protein in serS 5'region YNL225C CNM67 involved in cytokinesis YNL242W APG2 required for sporulation YNL246W YNL246W similarity to D.melanogaster SET protein YNL250W RAD50 DNA repair protein YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL262W POL2 DNA-directed DNA polymerase epsilon, catalytic subunit A YNL267W PIK1 phosphatidylinositol 4-kinase YNL271C BNI1 regulator of budding YNL273W TOF1 topoisomerase I interacting factor 1 YNL289W PCL1 cyclin, G1/S-specific YNL290W RFC3 DNA replication factor C, 40 kDa subunit YNL292W PUS4 pseudouridine synthase YNL298W CLA4 ser/thr protein kinase YNL299W TRF5 nuclear division protein YNL307C MCK1 ser/thr/tyr protein kinase YNL312W RFA2 DNA replication factor A, 36 kDa subunit YNL327W EGT2 cell-cycle regulation protein YNL330C RPD3 histone deacetylase B YNL339C YRF1-6 nearly identical to other subtelomerically encoded putative helicases YNR010W CSE2 subunit of RNA polymerase II mediator complex YOL006C TOP1 DNA topoisomerase I YOL021C DIS3 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YOL034W YOL034W similarity to S.pombe RAD18 and rpgL29 genes and other members of the SMC superfamily YOL043C NTG2 endonuclease III-like glycosylase 2 YOL069W NUF2 spindle pole body protein YOL076W MDM20 necessary for mitochondrial inheritance and organisation of the actin cytoskeleton YOL080C REX4 strong similarity to X.laevis XPMC2 protein and YGR276c YOL090W MSH2 DNA mismatch repair protein YOL091W SPO21 component of the meiotic plaque, required for formation of the prospore membrane YOL094C RFC4 DNA replication factor C, 37 kDa subunit YOL095C HMI1 mitochondrial DNA helicase YOL104C NDJ1 meiotic telomere protein YOL110W SHR5 RAS suppressor YOL115W TRF4 topoisomerase I-related protein YOL142W RRP40 protein involved in ribosomal RNA processing, component of the exosome complex responsible for 3' end processing and degradation of many RNA species YOL145C CTR9 required for G1 cyclin expression YOR005C DNL4 DNA ligase IV YOR026W BUB3 cell cycle arrest protein YOR028C CIN5 transcriptional activator YOR033C EXO1 exonuclease which interacts with MSH2P YOR057W SGT1 suppressor of G2 allele of SKP1 YOR058C ASE1 microtubule-associated protein (nonmotor) YOR061W CKA2 casein kinase II alpha' chain YOR077W RTS2 similarity to mouse KIN17 protein YOR101W RAS1 GTP-binding protein YOR149C SMP3 protein kinase C pathway protein YOR156C NFI1 interacts with CDC12P in 2-hybrid assay YOR177C MPC54 meiosis-specific component of the SPB YOR181W LAS17 component of actin cortical patches YOR195W SLK19 involved in control of spindle dynamics together with KAR3P YOR198C BFR1 maintenance of normal ploidy YOR208W PTP2 protein-tyrosine-phosphatase YOR213C SAS5 subunit of the RSC complex YOR217W RFC1 DNA replication factor C, 95 KD subunit YOR231W MKK1 ser/thr protein kinase YOR244W ESA1 histone acetyltransferase YOR249C APC5 component of the anaphase-promoting complex YOR257W CDC31 spindle pole body component, centrin YOR265W RBL2 beta-tubulin binding protein YOR272W YTM1 microtubule-interacting protein YOR298W MUM3 required for meiosis YOR330C MIP1 DNA-directed DNA polymerase gamma catalytic subunit, mitochondrial YOR346W REV1 DNA repair protein YOR349W CIN1 chromosome segregation protein YOR351C MEK1 ser/thr protein kinase YOR361C PRT1 translation initiation factor eIF3 subunit YOR368W RAD17 DNA damage checkpoint control protein YOR372C NDD1 protein required for nuclear division YOR373W NUD1 cell cycle regulatory protein YOR386W PHR1 deoxyribodipyrimidine photo-lyase YPL008W CHL1 protein of the DEAH box family YPL018W CTF19 involved in chromosome segregation YPL022W RAD1 component of the nucleotide excision repairosome YPL031C PHO85 cyclin-dependent protein kinase YPL042C SSN3 cyclin-dependent CTD kinase YPL046C ELC1 Elongin C transcription elongation factor YPL086C ELP3 subunit of elongator/RNAPII holoenzyme with histone acetylase activity YPL121C MEI5 meiotic protein YPL122C TFB2 TFIIH subunit (transcription/repair factor) YPL126W NAN1 weak similarity to fruit fly TFIID subunit p85 YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL139C UME1 negative regulator of meiosis YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL153C RAD53 ser/thr/tyr protein kinase YPL155C KIP2 kinesin-related protein YPL164C MLH3 insertion and deletion mismatch repair protein YPL167C REV3 DNA-directed DNA polymerase zeta subunit YPL174C NIP100 component of the dynactin complex YPL178W CBC2 small subunit of the nuclear cap-binding protein complex CBC YPL194W DDC1 DNA damage checkpoint protein YPL204W HRR25 casein kinase I, ser/thr/tyr protein kinase YPL209C IPL1 ser/thr protein kinase YPL235W RVB2 RUVB-like protein YPL239W YAR1 ankyrin repeat-containing protein YPL240C HSP82 heat shock protein YPL241C CIN2 involved in chromosome segregation YPL242C IQG1 involved in cytokinesis, has similarity to mammalian IQGAP proteins YPL255W BBP1 cell division control protein YPL256C CLN2 cyclin, G1/S-specific YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YPL269W KAR9 cortical protein required for cytoplasmic microtubule orientation and nuclear migration YPR007C SPO69 protein required for meiosis and sporulation YPR018W RLF2 chromatin assembly complex, subunit p90 YPR019W CDC54 member of the CDC46P/MCM2P/MCM3P family YPR025C CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPR046W MCM16 involved in chromosome segregation YPR056W TFB4 component of RNA polymerase transcription initiation TFIIH factor YPR082C DIB1 required for mitosis YPR103W PRE2 20S proteasome subunit (beta5) YPR111W DBF20 cell cycle protein kinase related to DBF2P YPR119W CLB2 cyclin, G2/M-specific YPR120C CLB5 cyclin, B-type YPR135W CTF4 DNA-directed DNA polymerase alpha-binding protein YPR141C KAR3 kinesin-related protein YPR161C SGV1 ser/thr protein kinase YPR162C ORC4 origin recognition complex, 56 KD subunit YPR175W DPB2 DNA-directed DNA polymerase epsilon, subunit B YPR193C HPA2 Histone and other Protein Acetyltransferase DNA processing (251 ORFs) 03.01 251 YAL015C NTG1 DNA repair protein YAL019W FUN30 similarity to helicases of the SNF2/RAD54 family YAL033W POP5 required for processing of tRNAs and rRNAs YAL040C CLN3 cyclin, G1/S-specific YAR007C RFA1 DNA replication factor A, 69 KD subunit YAR044W OSH1 similarity to human oxysterol binding protein (OSBP) YBL019W APN2 AP endonuclease, exonuclease III homolog YBL023C MCM2 member of the MCM2P,MCM3P,CDC46P family YBL035C POL12 DNA-directed DNA polymerase alpha, 70 KD subunit YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR073W RDH54 required for mitotic diploid-specific recombination and repair and meiosis YBR087W RFC5 DNA replication factor C, 40 KD subunit YBR088C POL30 Proliferating Cell Nuclear Antigen (PCNA) YBR098W MMS4 putative transcriptional (co)activator for DNA damage YBR114W RAD16 nucleotide excision repair protein YBR136W MEC1 cell cycle checkpoint protein YBR160W CDC28 cyclin-dependent protein kinase YBR195C MSI1 chromatin assembly complex, subunit p50 YBR202W CDC47 cell division control protein YBR238C YBR238C strong similarity to general chromatin factor SPT16P YBR272C HSM3 mismatch repair protein YBR278W DPB3 DNA-directed DNA polymerase epsilon, subunit C YCR014C POL4 DNA polymerase YCR028C-A RIM1 ssDNA-binding protein, mitochondrial YCR052W RSC6 subunit of the RSC complex YCR066W RAD18 DNA repair protein YCR077C PAT1 topoisomerase II-associated protein YCR092C MSH3 DNA mismatch repair protein YDL017W CDC7 protein kinase YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL059C RAD59 recombination and DNA repair protein YDL088C ASM4 component of the karyopherin docking complex of the nuclear pore complex YDL101C DUN1 protein kinase YDL102W CDC2 DNA-directed DNA polymerase delta, catalytic 125 KD subunit YDL108W KIN28 cyclin-dependent ser/thr protein kinase YDL164C CDC9 DNA ligase YDL200C MGT1 O6-methylguanine DNA repair methyltransferase YDR004W RAD57 DNA repair protein YDR030C RAD28 protein involved in the same pathway as RAD26P, has beta-transducin (WD-40) repeats YDR052C DBF4 regulatory subunit for CDC7P protein kinase YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR061W YDR061W similarity to E.coli modF and photorepair protein phrA YDR076W RAD55 DNA repair protein YDR096W GIS1 DNA damage-responsive repressor of PHR1 YDR097C MSH6 DNA mismatch repair protein YDR110W FOB1 DNA replication fork blocking protein YDR138W HPR1 hyperrecombination protein related to TOP1P YDR182W CDC1 cell division control protein YDR190C RVB1 RUVB-like protein YDR206W EBS1 similarity to EST1 protein YDR217C RAD9 DNA repair checkpoint protein YDR227W SIR4 silencing regulatory and DNA-repair protein YDR296W MHR1 Involved in mitochondrial homologous DNA recombination YDR311W TFB1 TFIIH subunit (transcription initiation factor), 75 kD YDR364C CDC40 cell division control protein YDR369C XRS2 DNA repair protein YDR386W MUS81 involved in the repair of UV and methylation induced DNA damage YDR419W RAD30 DNA repair protein YDR460W TFB3 TFIIH subunit (transcription/repair factor) YDR499W LCD1 cell cycle checkpoint protein YDR545W YRF1-1 Y'-helicase protein 1 YEL019C MMS21 DNA repair protein YEL032W MCM3 replication initiation protein YEL037C RAD23 nucleotide excision repair protein (ubiquitin-like protein) YEL066W HPA3 histone and other protein acetyltransferase YER070W RNR1 ribonucleoside-diphosphate reductase, large subunit YER095W RAD51 DNA repair protein YER142C MAG1 3-methyladenine DNA glycosylase YER162C RAD4 excision repair protein YER171W RAD3 DNA helicase/ATPase YER173W RAD24 cell cycle checkpoint protein YER176W ECM32 DNA dependent ATPase/DNA helicase B YER179W DMC1 meiosis-specific protein YER190W YRF1-2 Y'-helicase protein 1 YFL003C MSH4 meiosis-specific protein YFL009W CDC4 cell division control protein YFL014W HSP12 heat shock protein YFL036W RPO41 DNA-directed RNA polymerase, mitochondrial YFR023W PES4 DNA-directed DNA polymerase epsilon suppressor YFR027W ECO1 involved in sister chromatid cohesion during replication YFR028C CDC14 dual specificity phosphatase YFR037C RSC8 subunit of the RSC complex YFR038W YFR038W strong similarity to mouse lymphocyte specific helicase YGL025C PGD1 mediator complex subunit YGL043W DST1 TFIIS (transcription elongation factor) YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL087C MMS2 part of the error-free postreplication repair pathway YGL090W LIF1 DNA ligase IV interacting factor YGL127C SOH1 allows HPR1 null mutant to grow at 37 deg. YGL163C RAD54 DNA-dependent ATPase of the SNF2P family YGL173C KEM1 multifunctional nuclease YGL175C SAE2 meiotic recombination protein YGL194C HOS2 putative histone deacetylase YGL201C MCM6 involved in replication YGL207W SPT16 general chromatin factor YGL213C SKI8 antiviral protein of the beta-transducin (WD-40) repeat family YGL249W ZIP2 required for meiotic recombination and disjunction YGR056W RSC1 member of RSC complex, which remodels the structure of chromatin YGR063C SPT4 transcription elongation protein YGR109C CLB6 cyclin, B-type YGR116W SPT6 transcription elongation protein YGR132C PHB1 prohibitin, antiproliferative protein YGR144W THI4 involved in thiamine biosynthesis and DNA repair YGR180C RNR4 ribonucleotide reductase small subunit YGR231C PHB2 Prohibitin YGR252W GCN5 histone acetyltransferase YGR258C RAD2 structure-specific nuclease of the nucleotide excision repairosome YGR274C TAF145 TFIID subunit (TBP-associated factor), 145 kD YHL022C SPO11 catalytic subunit of the meiotic double strand break transesterase YHR031C RRM3 DNA helicase involved in rDNA replication and Ty1 transposition YHR086W NAM8 meiotic recombination protein YHR118C ORC6 origin recognition complex, 50 KD subunit YHR119W SET1 involved in chromatin-mediated gene regulation YHR120W MSH1 DNA mismatch repair protein, mitochondrial YHR157W REC104 meiosis-specific protein YHR164C DNA2 DNA helicase YIL009C-A EST3 subunit of the telomerase YIL036W CST6 ATF/CREB activator YIL066C RNR3 ribonucleotide reductase, repair inducible large subunit YIL072W HOP1 meiosis-specific protein YIL126W STH1 subunit of the RSC complex YIL128W MET18 involved in NER repair and RNA polymerase II transcription YIL139C REV7 DNA polymerase zeta subunit YIL143C SSL2 DNA helicase YIL150C DNA43 required for S-phase initiation or completion YIL153W RRD1 strong similarity to human phosphotyrosyl phosphatase activator YIR002C MPH1 protection of the genome from spontaneous and chemically induced damage YIR008C PRI1 DNA-directed DNA polymerase alpha 48kDa subunit (DNA primase) YIR033W MGA2 may be involved in the remodeling chromatin structure YJL026W RNR2 ribonucleoside-diphosphate reductase, small subunit YJL065C YJL065C weak similarity to DNA-directed DNA polymerase II chain C YJL090C DPB11 involved in DNA replication and S-phase checkpoint YJL092W HPR5 ATP-dependent DNA helicase YJL173C RFA3 DNA replication factor A, 13 KD subunit YJL194W CDC6 cell division control protein YJR006W HYS2 DNA-directed DNA polymerase delta, 55 KD subunit YJR021C REC107 meiotic recombination protein YJR035W RAD26 DNA repair and recombination protein YJR043C POL32 polymerase-associated gene, third (55 kDa) subunit of DNA polymerase delta YJR046W TAH11 weak similarity to Xenopus vimentin 4 YJR052W RAD7 nucleotide excision repair protein YJR068W RFC2 DNA replication factor C, 41 KD subunit YJR144W MGM101 mitochondrial genome maintenance protein YKL011C CCE1 cruciform-cutting endonuclease, mitochondrial YKL020C SPT23 dosage-dependent suppressor of Ty-induced promotor mutations YKL045W PRI2 DNA-directed DNA polymerase alpha , 58 KD subunit (DNA primase) YKL108W SLD2 chromosomal DNA replication protein YKL112W ABF1 ARS-binding factor YKL113C RAD27 ssDNA endonuclease and 5'-3'exonuclease YKL114C APN1 AP endonuclease YKL145W RPT1 26S proteasome regulatory subunit YKR008W RSC4 member of RSC complex, which remodels the structure of chromatin YKR095W MLP1 myosin-like protein related to USO1P YLL004W ORC3 origin recognition complex, 62 kDa subunit YLR005W SSL1 TFIIH subunit (transcription initiation factor), factor B YLR010C TEN1 involved in telomere length regulation and telomere end protection YLR032W RAD5 DNA helicase YLR035C MLH2 similarity to human mutL protein homolog, mouse PMS2, MLH1P and PMS1P YLR103C CDC45 required for minichromosome maintenance and initiation of chromosomal DNA replication YLR182W SWI6 transcription factor YLR233C EST1 telomere elongation protein YLR263W RED1 meiosis-specific protein YLR274W CDC46 cell division control protein YLR288C MEC3 G2-specific checkpoint protein YLR318W EST2 catalytic subunit of the telomerase YLR321C SFH1 subunit of the RSC complex YLR329W REC102 meiotic recombination protein YLR357W RSC2 member of RSC complex, which remodels the structure of chromatin YLR369W SSQ1 mitochondrial heat shock protein 70 YLR383W RHC18 recombination repair protein YLR394W CST9 protein required for synapsis, meiotic recombination, sporulation, proper chromosome segregation, and synaptonemal complex formation YLR442C SIR3 silencing regulatory and DNA-repair protein YLR466W YRF1-4 protein with similarity to other subtelomerically-coded Y'-helicase proteins YML010W SPT5 transcription elongation protein YML021C UNG1 uracil-DNA glycosylase YML032C RAD52 recombination and DNA repair protein YML058W SML1 protein inhibitor of ribonucleotide reductase YML058W-A HUG1 hydroxyurea and UV and gamma radiation induced YML060W OGG1 8-oxoguanine DNA glycosylase YML061C PIF1 DNA helicase involved in mitochondrial DNA repair and telomere length YML065W ORC1 origin recognition complex, 104 KD subunit YML069W POB3 protein that binds to DNA polymerase I (PolI) YML095C RAD10 DNA repair protein YML102W CAC2 chromatin assembly complex, subunit p60 YMR001C CDC5 involved in regulation of DNA replication YMR035W IMP2 mitochondrial inner membrane protease subunit YMR072W ABF2 high mobility group protein YMR106C YKU80 component of DNA end-joining repair pathway YMR137C PSO2 DNA repair protein YMR167W MLH1 DNA mismatch repair protein YMR190C SGS1 DNA helicase YMR201C RAD14 nucleotide excision repair protein YMR224C MRE11 DNA repair and meiotic recombination protein YMR228W MTF1 RNA polymerase specific factor, mitochondrial YMR241W YHM2 yeast suppressor gene of HM (mitochondrial histone) mutant (ABF2) YMR284W YKU70 high-affinity DNA-binding protein YMR290C HAS1 helicase associated with SET1P YNL021W HDA1 histone deacetylase A YNL082W PMS1 DNA mismatch repair protein YNL088W TOP2 DNA topoisomerase II (ATP-hydrolysing) YNL102W POL1 DNA-directed DNA polymerase alpha, 180 KD subunit YNL210W MER1 meiotic recombination protein YNL213C YNL213C similarity to hypothetical protein Neurospora crassa YNL218W MGS1 similarity to E.coli hypothetical protein in serS 5'region YNL250W RAD50 DNA repair protein YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL262W POL2 DNA-directed DNA polymerase epsilon, catalytic subunit A YNL273W TOF1 topoisomerase I interacting factor 1 YNL290W RFC3 DNA replication factor C, 40 kDa subunit YNL312W RFA2 DNA replication factor A, 36 kDa subunit YNL330C RPD3 histone deacetylase B YNL339C YRF1-6 nearly identical to other subtelomerically encoded putative helicases YOL006C TOP1 DNA topoisomerase I YOL034W YOL034W similarity to S.pombe RAD18 and rpgL29 genes and other members of the SMC superfamily YOL043C NTG2 endonuclease III-like glycosylase 2 YOL090W MSH2 DNA mismatch repair protein YOL094C RFC4 DNA replication factor C, 37 kDa subunit YOL095C HMI1 mitochondrial DNA helicase YOL115W TRF4 topoisomerase I-related protein YOL142W RRP40 protein involved in ribosomal RNA processing, component of the exosome complex responsible for 3' end processing and degradation of many RNA species YOR005C DNL4 DNA ligase IV YOR033C EXO1 exonuclease which interacts with MSH2P YOR077W RTS2 similarity to mouse KIN17 protein YOR213C SAS5 subunit of the RSC complex YOR217W RFC1 DNA replication factor C, 95 KD subunit YOR244W ESA1 histone acetyltransferase YOR330C MIP1 DNA-directed DNA polymerase gamma catalytic subunit, mitochondrial YOR346W REV1 DNA repair protein YOR351C MEK1 ser/thr protein kinase YOR368W RAD17 DNA damage checkpoint control protein YOR386W PHR1 deoxyribodipyrimidine photo-lyase YPL022W RAD1 component of the nucleotide excision repairosome YPL086C ELP3 subunit of elongator/RNAPII holoenzyme with histone acetylase activity YPL121C MEI5 meiotic protein YPL122C TFB2 TFIIH subunit (transcription/repair factor) YPL153C RAD53 ser/thr/tyr protein kinase YPL164C MLH3 insertion and deletion mismatch repair protein YPL167C REV3 DNA-directed DNA polymerase zeta subunit YPL194W DDC1 DNA damage checkpoint protein YPL204W HRR25 casein kinase I, ser/thr/tyr protein kinase YPL235W RVB2 RUVB-like protein YPL256C CLN2 cyclin, G1/S-specific YPR018W RLF2 chromatin assembly complex, subunit p90 YPR019W CDC54 member of the CDC46P/MCM2P/MCM3P family YPR025C CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPR056W TFB4 component of RNA polymerase transcription initiation TFIIH factor YPR120C CLB5 cyclin, B-type YPR135W CTF4 DNA-directed DNA polymerase alpha-binding protein YPR162C ORC4 origin recognition complex, 56 KD subunit YPR175W DPB2 DNA-directed DNA polymerase epsilon, subunit B YPR193C HPA2 Histone and other Protein Acetyltransferase DNA synthesis and replication (94 ORFs) 03.01.03 94 YAL033W POP5 required for processing of tRNAs and rRNAs YAL040C CLN3 cyclin, G1/S-specific YAR007C RFA1 DNA replication factor A, 69 KD subunit YBL023C MCM2 member of the MCM2P,MCM3P,CDC46P family YBL035C POL12 DNA-directed DNA polymerase alpha, 70 KD subunit YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR087W RFC5 DNA replication factor C, 40 KD subunit YBR088C POL30 Proliferating Cell Nuclear Antigen (PCNA) YBR160W CDC28 cyclin-dependent protein kinase YBR195C MSI1 chromatin assembly complex, subunit p50 YBR202W CDC47 cell division control protein YBR278W DPB3 DNA-directed DNA polymerase epsilon, subunit C YCR028C-A RIM1 ssDNA-binding protein, mitochondrial YCR077C PAT1 topoisomerase II-associated protein YDL017W CDC7 protein kinase YDL102W CDC2 DNA-directed DNA polymerase delta, catalytic 125 KD subunit YDL164C CDC9 DNA ligase YDR052C DBF4 regulatory subunit for CDC7P protein kinase YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR110W FOB1 DNA replication fork blocking protein YDR206W EBS1 similarity to EST1 protein YDR364C CDC40 cell division control protein YDR499W LCD1 cell cycle checkpoint protein YEL032W MCM3 replication initiation protein YER070W RNR1 ribonucleoside-diphosphate reductase, large subunit YER176W ECM32 DNA dependent ATPase/DNA helicase B YFL009W CDC4 cell division control protein YFL036W RPO41 DNA-directed RNA polymerase, mitochondrial YFR027W ECO1 involved in sister chromatid cohesion during replication YFR028C CDC14 dual specificity phosphatase YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL201C MCM6 involved in replication YGR109C CLB6 cyclin, B-type YGR132C PHB1 prohibitin, antiproliferative protein YGR180C RNR4 ribonucleotide reductase small subunit YGR231C PHB2 Prohibitin YHR118C ORC6 origin recognition complex, 50 KD subunit YHR164C DNA2 DNA helicase YIL009C-A EST3 subunit of the telomerase YIL036W CST6 ATF/CREB activator YIL066C RNR3 ribonucleotide reductase, repair inducible large subunit YIL139C REV7 DNA polymerase zeta subunit YIL150C DNA43 required for S-phase initiation or completion YIR008C PRI1 DNA-directed DNA polymerase alpha 48kDa subunit (DNA primase) YJL026W RNR2 ribonucleoside-diphosphate reductase, small subunit YJL065C YJL065C weak similarity to DNA-directed DNA polymerase II chain C YJL090C DPB11 involved in DNA replication and S-phase checkpoint YJL173C RFA3 DNA replication factor A, 13 KD subunit YJL194W CDC6 cell division control protein YJR006W HYS2 DNA-directed DNA polymerase delta, 55 KD subunit YJR043C POL32 polymerase-associated gene, third (55 kDa) subunit of DNA polymerase delta YJR046W TAH11 weak similarity to Xenopus vimentin 4 YJR068W RFC2 DNA replication factor C, 41 KD subunit YKL045W PRI2 DNA-directed DNA polymerase alpha , 58 KD subunit (DNA primase) YKL108W SLD2 chromosomal DNA replication protein YKL112W ABF1 ARS-binding factor YKL113C RAD27 ssDNA endonuclease and 5'-3'exonuclease YLL004W ORC3 origin recognition complex, 62 kDa subunit YLR010C TEN1 involved in telomere length regulation and telomere end protection YLR103C CDC45 required for minichromosome maintenance and initiation of chromosomal DNA replication YLR182W SWI6 transcription factor YLR233C EST1 telomere elongation protein YLR274W CDC46 cell division control protein YLR318W EST2 catalytic subunit of the telomerase YLR369W SSQ1 mitochondrial heat shock protein 70 YML058W SML1 protein inhibitor of ribonucleotide reductase YML065W ORC1 origin recognition complex, 104 KD subunit YML102W CAC2 chromatin assembly complex, subunit p60 YMR001C CDC5 involved in regulation of DNA replication YMR072W ABF2 high mobility group protein YMR241W YHM2 yeast suppressor gene of HM (mitochondrial histone) mutant (ABF2) YMR284W YKU70 high-affinity DNA-binding protein YNL088W TOP2 DNA topoisomerase II (ATP-hydrolysing) YNL102W POL1 DNA-directed DNA polymerase alpha, 180 KD subunit YNL213C YNL213C similarity to hypothetical protein Neurospora crassa YNL218W MGS1 similarity to E.coli hypothetical protein in serS 5'region YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL262W POL2 DNA-directed DNA polymerase epsilon, catalytic subunit A YNL290W RFC3 DNA replication factor C, 40 kDa subunit YNL312W RFA2 DNA replication factor A, 36 kDa subunit YOL006C TOP1 DNA topoisomerase I YOL094C RFC4 DNA replication factor C, 37 kDa subunit YOL095C HMI1 mitochondrial DNA helicase YOL115W TRF4 topoisomerase I-related protein YOR217W RFC1 DNA replication factor C, 95 KD subunit YOR330C MIP1 DNA-directed DNA polymerase gamma catalytic subunit, mitochondrial YPL167C REV3 DNA-directed DNA polymerase zeta subunit YPL256C CLN2 cyclin, G1/S-specific YPR018W RLF2 chromatin assembly complex, subunit p90 YPR019W CDC54 member of the CDC46P/MCM2P/MCM3P family YPR120C CLB5 cyclin, B-type YPR135W CTF4 DNA-directed DNA polymerase alpha-binding protein YPR162C ORC4 origin recognition complex, 56 KD subunit YPR175W DPB2 DNA-directed DNA polymerase epsilon, subunit B DNA recombination and DNA repair (153 ORFs) 03.01.05 153 YAL015C NTG1 DNA repair protein YAL019W FUN30 similarity to helicases of the SNF2/RAD54 family YAR007C RFA1 DNA replication factor A, 69 KD subunit YBL019W APN2 AP endonuclease, exonuclease III homolog YBR073W RDH54 required for mitotic diploid-specific recombination and repair and meiosis YBR088C POL30 Proliferating Cell Nuclear Antigen (PCNA) YBR098W MMS4 putative transcriptional (co)activator for DNA damage YBR114W RAD16 nucleotide excision repair protein YBR136W MEC1 cell cycle checkpoint protein YBR272C HSM3 mismatch repair protein YCR014C POL4 DNA polymerase YCR066W RAD18 DNA repair protein YCR077C PAT1 topoisomerase II-associated protein YCR092C MSH3 DNA mismatch repair protein YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL059C RAD59 recombination and DNA repair protein YDL088C ASM4 component of the karyopherin docking complex of the nuclear pore complex YDL101C DUN1 protein kinase YDL102W CDC2 DNA-directed DNA polymerase delta, catalytic 125 KD subunit YDL108W KIN28 cyclin-dependent ser/thr protein kinase YDL164C CDC9 DNA ligase YDL200C MGT1 O6-methylguanine DNA repair methyltransferase YDR004W RAD57 DNA repair protein YDR030C RAD28 protein involved in the same pathway as RAD26P, has beta-transducin (WD-40) repeats YDR061W YDR061W similarity to E.coli modF and photorepair protein phrA YDR076W RAD55 DNA repair protein YDR096W GIS1 DNA damage-responsive repressor of PHR1 YDR097C MSH6 DNA mismatch repair protein YDR110W FOB1 DNA replication fork blocking protein YDR138W HPR1 hyperrecombination protein related to TOP1P YDR182W CDC1 cell division control protein YDR217C RAD9 DNA repair checkpoint protein YDR227W SIR4 silencing regulatory and DNA-repair protein YDR296W MHR1 Involved in mitochondrial homologous DNA recombination YDR311W TFB1 TFIIH subunit (transcription initiation factor), 75 kD YDR369C XRS2 DNA repair protein YDR386W MUS81 involved in the repair of UV and methylation induced DNA damage YDR419W RAD30 DNA repair protein YDR460W TFB3 TFIIH subunit (transcription/repair factor) YDR499W LCD1 cell cycle checkpoint protein YDR545W YRF1-1 Y'-helicase protein 1 YEL019C MMS21 DNA repair protein YEL037C RAD23 nucleotide excision repair protein (ubiquitin-like protein) YER095W RAD51 DNA repair protein YER142C MAG1 3-methyladenine DNA glycosylase YER162C RAD4 excision repair protein YER171W RAD3 DNA helicase/ATPase YER173W RAD24 cell cycle checkpoint protein YER176W ECM32 DNA dependent ATPase/DNA helicase B YER179W DMC1 meiosis-specific protein YER190W YRF1-2 Y'-helicase protein 1 YFL003C MSH4 meiosis-specific protein YFL014W HSP12 heat shock protein YFR023W PES4 DNA-directed DNA polymerase epsilon suppressor YFR038W YFR038W strong similarity to mouse lymphocyte specific helicase YGL025C PGD1 mediator complex subunit YGL043W DST1 TFIIS (transcription elongation factor) YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL087C MMS2 part of the error-free postreplication repair pathway YGL090W LIF1 DNA ligase IV interacting factor YGL127C SOH1 allows HPR1 null mutant to grow at 37 deg. YGL163C RAD54 DNA-dependent ATPase of the SNF2P family YGL173C KEM1 multifunctional nuclease YGL175C SAE2 meiotic recombination protein YGL213C SKI8 antiviral protein of the beta-transducin (WD-40) repeat family YGL249W ZIP2 required for meiotic recombination and disjunction YGR063C SPT4 transcription elongation protein YGR116W SPT6 transcription elongation protein YGR144W THI4 involved in thiamine biosynthesis and DNA repair YGR180C RNR4 ribonucleotide reductase small subunit YGR258C RAD2 structure-specific nuclease of the nucleotide excision repairosome YHL022C SPO11 catalytic subunit of the meiotic double strand break transesterase YHR031C RRM3 DNA helicase involved in rDNA replication and Ty1 transposition YHR086W NAM8 meiotic recombination protein YHR120W MSH1 DNA mismatch repair protein, mitochondrial YHR157W REC104 meiosis-specific protein YIL066C RNR3 ribonucleotide reductase, repair inducible large subunit YIL072W HOP1 meiosis-specific protein YIL128W MET18 involved in NER repair and RNA polymerase II transcription YIL139C REV7 DNA polymerase zeta subunit YIL143C SSL2 DNA helicase YIL153W RRD1 strong similarity to human phosphotyrosyl phosphatase activator YIR002C MPH1 protection of the genome from spontaneous and chemically induced damage YJL092W HPR5 ATP-dependent DNA helicase YJR006W HYS2 DNA-directed DNA polymerase delta, 55 KD subunit YJR021C REC107 meiotic recombination protein YJR035W RAD26 DNA repair and recombination protein YJR043C POL32 polymerase-associated gene, third (55 kDa) subunit of DNA polymerase delta YJR052W RAD7 nucleotide excision repair protein YJR144W MGM101 mitochondrial genome maintenance protein YKL011C CCE1 cruciform-cutting endonuclease, mitochondrial YKL113C RAD27 ssDNA endonuclease and 5'-3'exonuclease YKL114C APN1 AP endonuclease YKL145W RPT1 26S proteasome regulatory subunit YKR095W MLP1 myosin-like protein related to USO1P YLR005W SSL1 TFIIH subunit (transcription initiation factor), factor B YLR032W RAD5 DNA helicase YLR035C MLH2 similarity to human mutL protein homolog, mouse PMS2, MLH1P and PMS1P YLR182W SWI6 transcription factor YLR263W RED1 meiosis-specific protein YLR288C MEC3 G2-specific checkpoint protein YLR329W REC102 meiotic recombination protein YLR383W RHC18 recombination repair protein YLR394W CST9 protein required for synapsis, meiotic recombination, sporulation, proper chromosome segregation, and synaptonemal complex formation YLR442C SIR3 silencing regulatory and DNA-repair protein YLR466W YRF1-4 protein with similarity to other subtelomerically-coded Y'-helicase proteins YML021C UNG1 uracil-DNA glycosylase YML032C RAD52 recombination and DNA repair protein YML058W SML1 protein inhibitor of ribonucleotide reductase YML058W-A HUG1 hydroxyurea and UV and gamma radiation induced YML060W OGG1 8-oxoguanine DNA glycosylase YML061C PIF1 DNA helicase involved in mitochondrial DNA repair and telomere length YML069W POB3 protein that binds to DNA polymerase I (PolI) YML095C RAD10 DNA repair protein YMR035W IMP2 mitochondrial inner membrane protease subunit YMR072W ABF2 high mobility group protein YMR106C YKU80 component of DNA end-joining repair pathway YMR137C PSO2 DNA repair protein YMR167W MLH1 DNA mismatch repair protein YMR190C SGS1 DNA helicase YMR201C RAD14 nucleotide excision repair protein YMR224C MRE11 DNA repair and meiotic recombination protein YMR228W MTF1 RNA polymerase specific factor, mitochondrial YMR284W YKU70 high-affinity DNA-binding protein YNL082W PMS1 DNA mismatch repair protein YNL088W TOP2 DNA topoisomerase II (ATP-hydrolysing) YNL210W MER1 meiotic recombination protein YNL250W RAD50 DNA repair protein YNL262W POL2 DNA-directed DNA polymerase epsilon, catalytic subunit A YNL273W TOF1 topoisomerase I interacting factor 1 YNL339C YRF1-6 nearly identical to other subtelomerically encoded putative helicases YOL006C TOP1 DNA topoisomerase I YOL034W YOL034W similarity to S.pombe RAD18 and rpgL29 genes and other members of the SMC superfamily YOL043C NTG2 endonuclease III-like glycosylase 2 YOL090W MSH2 DNA mismatch repair protein YOL142W RRP40 protein involved in ribosomal RNA processing, component of the exosome complex responsible for 3' end processing and degradation of many RNA species YOR005C DNL4 DNA ligase IV YOR033C EXO1 exonuclease which interacts with MSH2P YOR077W RTS2 similarity to mouse KIN17 protein YOR346W REV1 DNA repair protein YOR351C MEK1 ser/thr protein kinase YOR368W RAD17 DNA damage checkpoint control protein YOR386W PHR1 deoxyribodipyrimidine photo-lyase YPL022W RAD1 component of the nucleotide excision repairosome YPL121C MEI5 meiotic protein YPL122C TFB2 TFIIH subunit (transcription/repair factor) YPL153C RAD53 ser/thr/tyr protein kinase YPL164C MLH3 insertion and deletion mismatch repair protein YPL167C REV3 DNA-directed DNA polymerase zeta subunit YPL194W DDC1 DNA damage checkpoint protein YPL204W HRR25 casein kinase I, ser/thr/tyr protein kinase YPR025C CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPR056W TFB4 component of RNA polymerase transcription initiation TFIIH factor DNA repair (88 ORFs) 03.01.05.01 88 YAL015C NTG1 DNA repair protein YAL019W FUN30 similarity to helicases of the SNF2/RAD54 family YBL019W APN2 AP endonuclease, exonuclease III homolog YBR073W RDH54 required for mitotic diploid-specific recombination and repair and meiosis YBR098W MMS4 putative transcriptional (co)activator for DNA damage YBR114W RAD16 nucleotide excision repair protein YCR066W RAD18 DNA repair protein YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL088C ASM4 component of the karyopherin docking complex of the nuclear pore complex YDL101C DUN1 protein kinase YDL102W CDC2 DNA-directed DNA polymerase delta, catalytic 125 KD subunit YDL108W KIN28 cyclin-dependent ser/thr protein kinase YDL164C CDC9 DNA ligase YDL200C MGT1 O6-methylguanine DNA repair methyltransferase YDR004W RAD57 DNA repair protein YDR061W YDR061W similarity to E.coli modF and photorepair protein phrA YDR076W RAD55 DNA repair protein YDR096W GIS1 DNA damage-responsive repressor of PHR1 YDR227W SIR4 silencing regulatory and DNA-repair protein YDR311W TFB1 TFIIH subunit (transcription initiation factor), 75 kD YDR369C XRS2 DNA repair protein YDR386W MUS81 involved in the repair of UV and methylation induced DNA damage YDR419W RAD30 DNA repair protein YDR460W TFB3 TFIIH subunit (transcription/repair factor) YEL019C MMS21 DNA repair protein YEL037C RAD23 nucleotide excision repair protein (ubiquitin-like protein) YER095W RAD51 DNA repair protein YER142C MAG1 3-methyladenine DNA glycosylase YER162C RAD4 excision repair protein YER171W RAD3 DNA helicase/ATPase YER176W ECM32 DNA dependent ATPase/DNA helicase B YFL014W HSP12 heat shock protein YFR023W PES4 DNA-directed DNA polymerase epsilon suppressor YFR038W YFR038W strong similarity to mouse lymphocyte specific helicase YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL087C MMS2 part of the error-free postreplication repair pathway YGL090W LIF1 DNA ligase IV interacting factor YGL163C RAD54 DNA-dependent ATPase of the SNF2P family YGR144W THI4 involved in thiamine biosynthesis and DNA repair YGR180C RNR4 ribonucleotide reductase small subunit YGR258C RAD2 structure-specific nuclease of the nucleotide excision repairosome YIL066C RNR3 ribonucleotide reductase, repair inducible large subunit YIL128W MET18 involved in NER repair and RNA polymerase II transcription YIL139C REV7 DNA polymerase zeta subunit YIL143C SSL2 DNA helicase YIL153W RRD1 strong similarity to human phosphotyrosyl phosphatase activator YIR002C MPH1 protection of the genome from spontaneous and chemically induced damage YJL092W HPR5 ATP-dependent DNA helicase YJR006W HYS2 DNA-directed DNA polymerase delta, 55 KD subunit YJR043C POL32 polymerase-associated gene, third (55 kDa) subunit of DNA polymerase delta YJR052W RAD7 nucleotide excision repair protein YJR144W MGM101 mitochondrial genome maintenance protein YKL113C RAD27 ssDNA endonuclease and 5'-3'exonuclease YKL114C APN1 AP endonuclease YKL145W RPT1 26S proteasome regulatory subunit YKR095W MLP1 myosin-like protein related to USO1P YLR005W SSL1 TFIIH subunit (transcription initiation factor), factor B YLR032W RAD5 DNA helicase YLR035C MLH2 similarity to human mutL protein homolog, mouse PMS2, MLH1P and PMS1P YLR288C MEC3 G2-specific checkpoint protein YLR442C SIR3 silencing regulatory and DNA-repair protein YML032C RAD52 recombination and DNA repair protein YML058W-A HUG1 hydroxyurea and UV and gamma radiation induced YML060W OGG1 8-oxoguanine DNA glycosylase YML061C PIF1 DNA helicase involved in mitochondrial DNA repair and telomere length YML095C RAD10 DNA repair protein YMR035W IMP2 mitochondrial inner membrane protease subunit YMR106C YKU80 component of DNA end-joining repair pathway YMR137C PSO2 DNA repair protein YMR201C RAD14 nucleotide excision repair protein YMR224C MRE11 DNA repair and meiotic recombination protein YMR284W YKU70 high-affinity DNA-binding protein YNL250W RAD50 DNA repair protein YNL262W POL2 DNA-directed DNA polymerase epsilon, catalytic subunit A YOL043C NTG2 endonuclease III-like glycosylase 2 YOR005C DNL4 DNA ligase IV YOR346W REV1 DNA repair protein YOR368W RAD17 DNA damage checkpoint control protein YOR386W PHR1 deoxyribodipyrimidine photo-lyase YPL022W RAD1 component of the nucleotide excision repairosome YPL122C TFB2 TFIIH subunit (transcription/repair factor) YPL153C RAD53 ser/thr/tyr protein kinase YPL164C MLH3 insertion and deletion mismatch repair protein YPL167C REV3 DNA-directed DNA polymerase zeta subunit YPL194W DDC1 DNA damage checkpoint protein YPL204W HRR25 casein kinase I, ser/thr/tyr protein kinase YPR025C CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPR056W TFB4 component of RNA polymerase transcription initiation TFIIH factor other DNA repair (1 ORF) 03.01.05.01.99 1 YPL164C MLH3 insertion and deletion mismatch repair protein DNA restriction or modification (32 ORFs) 03.01.09 32 YAR044W OSH1 similarity to human oxysterol binding protein (OSBP) YBR195C MSI1 chromatin assembly complex, subunit p50 YBR238C YBR238C strong similarity to general chromatin factor SPT16P YCR052W RSC6 subunit of the RSC complex YDR190C RVB1 RUVB-like protein YEL066W HPA3 histone and other protein acetyltransferase YFR037C RSC8 subunit of the RSC complex YGL194C HOS2 putative histone deacetylase YGL207W SPT16 general chromatin factor YGR056W RSC1 member of RSC complex, which remodels the structure of chromatin YGR063C SPT4 transcription elongation protein YGR116W SPT6 transcription elongation protein YGR252W GCN5 histone acetyltransferase YGR274C TAF145 TFIID subunit (TBP-associated factor), 145 kD YHR119W SET1 involved in chromatin-mediated gene regulation YIL126W STH1 subunit of the RSC complex YIR033W MGA2 may be involved in the remodeling chromatin structure YKL020C SPT23 dosage-dependent suppressor of Ty-induced promotor mutations YKR008W RSC4 member of RSC complex, which remodels the structure of chromatin YLR321C SFH1 subunit of the RSC complex YLR357W RSC2 member of RSC complex, which remodels the structure of chromatin YML010W SPT5 transcription elongation protein YML102W CAC2 chromatin assembly complex, subunit p60 YMR290C HAS1 helicase associated with SET1P YNL021W HDA1 histone deacetylase A YNL330C RPD3 histone deacetylase B YOR213C SAS5 subunit of the RSC complex YOR244W ESA1 histone acetyltransferase YPL086C ELP3 subunit of elongator/RNAPII holoenzyme with histone acetylase activity YPL235W RVB2 RUVB-like protein YPR018W RLF2 chromatin assembly complex, subunit p90 YPR193C HPA2 Histone and other Protein Acetyltransferase chromatin modification (32 ORFs) 03.01.09.05 32 YAR044W OSH1 similarity to human oxysterol binding protein (OSBP) YBR195C MSI1 chromatin assembly complex, subunit p50 YBR238C YBR238C strong similarity to general chromatin factor SPT16P YCR052W RSC6 subunit of the RSC complex YDR190C RVB1 RUVB-like protein YEL066W HPA3 histone and other protein acetyltransferase YFR037C RSC8 subunit of the RSC complex YGL194C HOS2 putative histone deacetylase YGL207W SPT16 general chromatin factor YGR056W RSC1 member of RSC complex, which remodels the structure of chromatin YGR063C SPT4 transcription elongation protein YGR116W SPT6 transcription elongation protein YGR252W GCN5 histone acetyltransferase YGR274C TAF145 TFIID subunit (TBP-associated factor), 145 kD YHR119W SET1 involved in chromatin-mediated gene regulation YIL126W STH1 subunit of the RSC complex YIR033W MGA2 may be involved in the remodeling chromatin structure YKL020C SPT23 dosage-dependent suppressor of Ty-induced promotor mutations YKR008W RSC4 member of RSC complex, which remodels the structure of chromatin YLR321C SFH1 subunit of the RSC complex YLR357W RSC2 member of RSC complex, which remodels the structure of chromatin YML010W SPT5 transcription elongation protein YML102W CAC2 chromatin assembly complex, subunit p60 YMR290C HAS1 helicase associated with SET1P YNL021W HDA1 histone deacetylase A YNL330C RPD3 histone deacetylase B YOR213C SAS5 subunit of the RSC complex YOR244W ESA1 histone acetyltransferase YPL086C ELP3 subunit of elongator/RNAPII holoenzyme with histone acetylase activity YPL235W RVB2 RUVB-like protein YPR018W RLF2 chromatin assembly complex, subunit p90 YPR193C HPA2 Histone and other Protein Acetyltransferase cell cycle (451 ORFs) 03.03 451 YAL009W SPO7 meiotic protein YAL016W TPD3 ser/thr protein phosphatase 2A, regulatory chain A YAL024C LTE1 GDP/GTP exchange factor YAL025C MAK16 nuclear viral propagation protein YAL029C MYO4 myosin heavy chain, unconventional (class V) isoform YAL034W-A MTW1 determining metaphase spindle length YAL040C CLN3 cyclin, G1/S-specific YAL041W CDC24 GTP/GDP exchange factor for CDC42P YAL047C SPC72 STU2P Interactant YAR003W SWD1 similarity to human RB protein binding protein YAR019C CDC15 protein kinase of the MAP kinase kinase kinase family YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBL020W RFT1 nuclear division protein YBL058W SHP1 potential regulatory subunit for GLC7P YBL063W KIP1 kinesin-related protein YBL079W NUP170 nuclear pore protein YBL084C CDC27 subunit of anaphase-promoting complex (cyclosome) YBL088C TEL1 telomere length control protein YBL097W BRN1 functional homologue of human BRRN1 YBL105C PKC1 ser/thr protein kinase YBR045C GIP1 GLC7-interacting protein YBR057C MUM2 meiotic protein YBR073W RDH54 required for mitotic diploid-specific recombination and repair and meiosis YBR078W ECM33 involved in cell wall biogenesis and architecture YBR079C RPG1 translation initiation factor eIF3 (p110 subunit) YBR087W RFC5 DNA replication factor C, 40 KD subunit YBR107C IML3 weak similarity to N.crassa chitin synthase YBR109C CMD1 calmodulin YBR133C HSL7 adapter in a regulatory pathway that relieves tyrosine phosphorylation of CDC28 YBR135W CKS1 cyclin-dependent kinases regulatory subunit YBR136W MEC1 cell cycle checkpoint protein YBR156C SLI15 Mitotic spindle protein involved in chromosome segregation YBR160W CDC28 cyclin-dependent protein kinase YBR186W PCH2 putative ATPase YBR200W BEM1 bud emergence mediator YBR202W CDC47 cell division control protein YBR211C AME1 actin related protein YBR215W HPC2 cell cycle regulatory protein YBR238C YBR238C strong similarity to general chromatin factor SPT16P YBR243C ALG7 UDP-N-acetylglucosamine-1-phosphate transferase YBR274W CHK1 regulats inhibitory Cdk phosphorylation of PDS1 YBR276C PPS1 protein tyrosine phosphatase YCL004W PGS1 phosphatidylglycerophosphate synthase YCL016C DCC1 part of an alternative RFC complex YCL024W KCC4 kinase coordinate cell cycle progression with the organization of the peripheralcytoskeleton YCL029C BIK1 nuclear fusion protein YCL048W YCL048W strong similarity to sporulation-specific protein SPS2P YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCR002C CDC10 cell division control protein YCR052W RSC6 subunit of the RSC complex YCR057C PWP2 periodic tryptophan protein YCR086W CSM1 involved in nuclear migration YCR094W CDC50 cell division cycle mutant YDL003W MCD1 Mitotic Chromosome Determinant YDL008W APC11 subunit of the anaphase promoting complex YDL017W CDC7 protein kinase YDL028C MPS1 serine/threonine/tyrosine protein kinase YDL029W ARP2 actin-like protein YDL047W SIT4 ser/thr protein phosphatase YDL056W MBP1 transcription factor, subunit of the MBF factor YDL064W UBC9 E2 ubiquitin-conjugating enzyme YDL108W KIN28 cyclin-dependent ser/thr protein kinase YDL114W YDL114W weak similarity to Rhizobium nodulation protein nodG YDL126C CDC48 microsomal protein of CDC48/PAS1/SEC18 family of ATPases YDL127W PCL2 cyclin, G1/S-specific YDL132W CDC53 controls G1/S transition YDL134C PPH21 protein ser/thr phosphatase PP2A-1 YDL154W MSH5 meiosis-specific protein YDL155W CLB3 cyclin, G2/M-specific YDL165W CDC36 transcription factor YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL220C CDC13 cell division control protein YDL225W SHS1 septin YDL226C GCS1 ADP-ribosylation factor GTPase-activating protein (ARF-GAP) YDR004W RAD57 DNA repair protein YDR022C CIS1 involved in suppression of CIK1 mutation YDR052C DBF4 regulatory subunit for CDC7P protein kinase YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR055W PST1 strong similarity to SPS2 protein YDR076W RAD55 DNA repair protein YDR082W STN1 involved in telomere length regulation YDR099W BMH2 suppressor of clathrin deficiency YDR108W GSG1 sporulation specific protein YDR113C PDS1 cell cycle regulator YDR118W APC4 subunit of the anaphase promoting complex YDR130C FIN1 weak similarity to sea urchin myosin heavy chain YDR137W RGP1 reduced growth phenotype protein YDR150W NUM1 nuclear migration protein YDR168W CDC37 cell division control protein YDR172W SUP35 eukaryotic peptide chain release factor GTP-binding subunit YDR180W SCC2 involved in sister chromatid cohesion YDR182W CDC1 cell division control protein YDR207C UME6 negative transcriptional regulator YDR217C RAD9 DNA repair checkpoint protein YDR218C SPR28 septin-related sporulation protein YDR254W CHL4 chromosome segregation protein YDR260C SWM1 developmentally regulated gene, is required for spore wall assembly YDR284C DPP1 diacylglycerol pyrophosphate phosphatase YDR285W ZIP1 synaptonemal complex protein YDR293C SSD1 involved in the tolerance to high concentration of Ca2+ YDR325W YCG1 Yeast Condensin G YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR356W NUF1 spindle pole body component YDR363W-A SEM1 regulator of exocytosis and pseudohyphal differentiation YDR364C CDC40 cell division control protein YDR369C XRS2 DNA repair protein YDR416W SYF1 synthetic lethal with CDC40 YDR440W DOT1 putative ATPase YDR457W TOM1 E3 ubiqitin ligase required for G2/M transition YDR488C PAC11 required in the absence of CIN8P YDR499W LCD1 cell cycle checkpoint protein YDR507C GIN4 ser/thr protein kinase YDR522C SPS2 sporulation-specific protein YDR523C SPS1 ser/thr protein kinase YEL037C RAD23 nucleotide excision repair protein (ubiquitin-like protein) YEL061C CIN8 kinesin-related protein YER007W PAC2 involved in the stabilization of microtubles YER016W BIM1 binding to microtubules YER044C-A MEI4 meiosis-specific protein YER066W YER066W strong similarity to cell division control protein CDC4P YER075C PTP3 protein tyrosine phosphatase YER095W RAD51 DNA repair protein YER111C SWI4 transcription factor YER122C GLO3 zinc finger protein YER123W YCK3 casein kinase, isoform 3 YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER155C BEM2 GTPase-activating protein YER173W RAD24 cell cycle checkpoint protein YER177W BMH1 14-3-3 protein involved in rapamycin-sensitive signalling YER179W DMC1 meiosis-specific protein YER180C ISC10 meiosis-specific protein YFL003C MSH4 meiosis-specific protein YFL008W SMC1 chromosome segregation protein YFL009W CDC4 cell division control protein YFL017C GNA1 essential acetyltransferase YFL029C CAK1 cdk-activating protein kinase YFL037W TUB2 beta-tubulin YFL039C ACT1 actin YFR027W ECO1 involved in sister chromatid cohesion during replication YFR028C CDC14 dual specificity phosphatase YFR031C SMC2 chromosome segregation protein YFR036W CDC26 subunit of anaphase-promoting complex (cyclosome) YFR037C RSC8 subunit of the RSC complex YFR040W SAP155 SIT4P-associated protein YFR052W RPN12 26S proteasome regulatory subunit YGL003C CDH1 substrate-specific activator of APC-dependent proteolysis YGL033W HOP2 required for pairing of homologous chromosomes YGL048C RPT6 26S proteasome regulatory subunit YGL056C SDS23 strong similarity to pombe SDS23 YGL061C DUO1 essential mitotic spindle protein YGL073W HSF1 heat shock transcription factor YGL075C MPS2 Protein of the nuclear envelope/endoplasmic reticulum required for spindle pole body assembly and normal chromosome segregation YGL086W MAD1 spindle assembly checkpoint protein YGL090W LIF1 DNA ligase IV interacting factor YGL106W MLC1 MYO2P light chain YGL116W CDC20 cell division control protein YGL155W CDC43 geranylgeranyltransferase beta subunit YGL158W RCK1 ser/thr protein kinase YGL163C RAD54 DNA-dependent ATPase of the SNF2P family YGL173C KEM1 multifunctional nuclease YGL175C SAE2 meiotic recombination protein YGL178W MPT5 multicopy suppressor of POP2 YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL190C CDC55 ser/thr phosphatase 2A regulatory subunit B YGL207W SPT16 general chromatin factor YGL213C SKI8 antiviral protein of the beta-transducin (WD-40) repeat family YGL215W CLG1 cyclin-like protein YGL216W KIP3 kinesin-related protein required for nuclear migration YGL229C SAP4 SIT4P-associated protein YGL240W DOC1 component of the anaphase promoting complex YGL249W ZIP2 required for meiotic recombination and disjunction YGR023W MTL1 potential cell wall stres sensor YGR029W ERV1 mitochondrial biogenesis and regulation of cell cycle YGR044C RME1 zinc-finger transcription factor YGR049W SCM4 CDC4 suppressor YGR078C PAC10 GIM4 - Gim complex component YGR092W DBF2 ser/thr protein kinase related to DBF20P YGR098C ESP1 required for sister chromatid separation YGR108W CLB1 cyclin, G2/M-specific YGR109C CLB6 cyclin, B-type YGR113W DAM1 essential mitotic spindle pole protein YGR132C PHB1 prohibitin, antiproliferative protein YGR140W CBF2 kinetochore protein complex CBF3, 110 KD subunit YGR179C OKP1 component of centromere/kinetochore-associated protein network YGR188C BUB1 ser/thr protein kinase YGR209C TRX2 thioredoxin II YGR230W BNS1 Bypasses Need for SPO12P YGR231C PHB2 Prohibitin YGR245C SDA1 required for normal organization of the actin cytoskeleton; required for passage through Start YGR253C PUP2 20S proteasome subunit(alpha5) YGR258C RAD2 structure-specific nuclease of the nucleotide excision repairosome YHL022C SPO11 catalytic subunit of the meiotic double strand break transesterase YHL024W RIM4 No sporulation YHL027W RIM101 meiotic regulatory protein YHR004C NEM1 required for nuclear morphology YHR013C ARD1 protein N-acetyltransferase subunit YHR014W SPO13 meiosis-specific protein YHR023W MYO1 myosin-1 isoform (type II myosin) heavy chain YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR079C-A SAE3 meiosis specific protein YHR086W NAM8 meiotic recombination protein YHR101C BIG1 big cells phenotype YHR102W KIC1 ser/thr protein kinase that interacts with CDC31P YHR107C CDC12 septin YHR119W SET1 involved in chromatin-mediated gene regulation YHR124W NDT80 meiosis-specific protein YHR129C ARP1 centractin YHR135C YCK1 casein kinase I isoform YHR152W SPO12 sporulation protein YHR153C SPO16 sporulation protein YHR157W REC104 meiosis-specific protein YHR165C PRP8 U5 snRNP protein, pre-mRNA splicing factor YHR166C CDC23 subunit of anaphase-promoting complex (cyclosome) YHR172W SPC97 spindle pole body component YHR184W SSP1 essential for meiosis and spore formation YHR205W SCH9 serine/threonine protein kinase involved in stress response and nutrient-sensing signaling pathway YHR206W SKN7 transcription factor with similarity to HSF1P YHR208W BAT1 branched chain amino acid aminotransferase, mitochondrial YIL026C IRR1 essential protein YIL031W ULP2 SMT3P-specific protease, degrades conjugated ubiquitin-like protein SMT3P YIL035C CKA1 casein kinase II, catalytic alpha chain YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL072W HOP1 meiosis-specific protein YIL095W PRK1 serine/threonine protein kinase involved in regulation of actin cytoskeleton organization YIL106W MOB1 required for completion of mitosis and maintenance of ploidy YIL123W SIM1 involved in cell cycle regulation and aging YIL126W STH1 subunit of the RSC complex YIL150C DNA43 required for S-phase initiation or completion YIR008C PRI1 DNA-directed DNA polymerase alpha 48kDa subunit (DNA primase) YIR024C GIF1 G1 Factor needed for normal G1 phase YIR026C YVH1 protein tyrosine phosphatase YJL005W CYR1 adenylate cyclase YJL013C MAD3 spindle-assembly checkpoint protein YJL030W MAD2 spindle-assembly checkpoint protein YJL034W KAR2 nuclear fusion protein YJL074C SMC3 required for structural maintenance of chromosomes YJL080C SCP160 required for maintenance of exact ploidy YJL090C DPB11 involved in DNA replication and S-phase checkpoint YJL095W BCK1 ser/thr protein kinase of the MEKK family YJL098W SAP185 SIT4P-associating protein YJL106W IME2 ser/thr protein kinase YJL141C YAK1 ser/thr protein kinase YJL146W IDS2 IME2-dependent signaling protein YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJL187C SWE1 ser/tyr dual-specifity protein kinase YJL194W CDC6 cell division control protein YJR021C REC107 meiotic recombination protein YJR053W BFA1 spindle assembly checkpoint protein YJR060W CBF1 kinetochore protein YJR066W TOR1 phosphatidylinositol 3-kinase YJR068W RFC2 DNA replication factor C, 41 KD subunit YJR076C CDC11 septin YJR089W BIR1 member of the inhibitor of apoptosis family, participate in chromosome segregation events YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR091C JSN1 suppresses the high-temperature lethality of TUB2-150 YJR094C IME1 transcription factor required for sporulation YJR112W NNF1 nuclear envelope protein YJR135C MCM22 required for maintenance of chromosomes and minichromosomes YJR140C HIR3 involved in cell cycle regulation of histone transcription YKL017C HCS1 DNA helicase A YKL022C CDC16 subunit of anaphase-promoting complex (cyclosome) YKL042W SPC42 spindle pole body component YKL048C ELM1 ser/thr-specific protein kinase YKL049C CSE4 component of the core centromere YKL089W MIF2 required for normal chromosome segregation and spindle integrity YKL101W HSL1 ser/thr protein kinase, coupling septin ring assembly to cell cycle progression YKL112W ABF1 ARS-binding factor YKL145W RPT1 26S proteasome regulatory subunit YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL179C YKL179C similarity to NUF1P YKL193C SDS22 regulatory subunit for the mitotic function of type I protein phosphatase YKL203C TOR2 phosphatidylinositol 3-kinase YKR028W SAP190 SIT4P-associated protein YKR031C SPO14 phospholipase D YKR042W UTH1 involved in the aging process YKR046C YKR046C hypothetical protein YKR048C NAP1 nucleosome assembly protein I YKR054C DYN1 dynein heavy chain, cytosolic YKR063C LAS1 involved in cell morphogenesis, cytoskeletal regulation and bud formation YKR072C SIS2 involved in cell cycle-specific gene expression YLL003W SFI1 similarity to Xenopus laevis XCAP-C YLL016W SDC25 GDP/GTP exchange factor (GEF) YLL017W YLL017W maybe part of SCD25 YLR043C TRX1 thioredoxin I YLR075W RPL10 60S large subunit ribosomal protein YLR079W SIC1 p40 inhibitor of CDC28P-Clb protein kinase complex YLR102C APC9 subunit of the Anaphase Promoting Complex YLR103C CDC45 required for minichromosome maintenance and initiation of chromosomal DNA replication YLR117C CLF1 strong similarity to Drosophila putative cell cycle control protein crn YLR127C APC2 component of the anaphase promoting complex YLR129W DIP2 DOM34P-interacting protein YLR131C ACE2 metallothionein expression activator YLR175W CBF5 putative rRNA pseuduridine synthase YLR178C TFS1 CDC25-dependent nutrient- and ammonia-response cell-cycle regulator YLR179C YLR179C similarity to TFS1P YLR182W SWI6 transcription factor YLR210W CLB4 cyclin, G2/M-specific YLR212C TUB4 gamma tubulin YLR215C CDC123 strong similarity to rat cell cycle progression related D123 protein YLR226W BUR2 divergent CDK-cyclin complex YLR229C CDC42 GTP-binding protein of RAS superfamily YLR234W TOP3 DNA topoisomerase III YLR248W RCK2 Ca/calmodulin-dependent ser/thr protein kinase YLR263W RED1 meiosis-specific protein YLR274W CDC46 cell division control protein YLR286C CTS1 endochitinase YLR288C MEC3 G2-specific checkpoint protein YLR299W ECM38 gamma-glutamyltransferase, involved in glutathione synthesis YLR305C STT4 phosphatidylinositol-4-kinase YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR314C CDC3 cell division control protein YLR321C SFH1 subunit of the RSC complex YLR329W REC102 meiotic recombination protein YLR332W MID2 mating process protein YLR356W YLR356W similarity to SCM4 protein YLR403W SFP1 zinc finger protein YML031W NDC1 nuclear envelope protein YML064C TEM1 GTP-binding protein of the RAS superfamily YML085C TUB1 alpha-1 tubulin YML104C MDM1 intermediate filament protein YML109W ZDS2 multicopy suppressor of SIN4 YML115C VAN1 vanadate resistance protein YML124C TUB3 alpha-3 tubulin YMR001C CDC5 involved in regulation of DNA replication YMR028W TAP42 component of the Tor signaling pathway YMR032W HOF1 involved in cytokinesis YMR036C MIH1 M-phase inducing protein tyrosine phosphatase YMR043W MCM1 transcription factor of the MADS box family YMR052W FAR3 involved in pheromone-mediated cell cycle arrest YMR055C BUB2 cell cycle arrest protein YMR076C PDS5 precocious dissociation of sister chromatids YMR078C CTF18 required for accurate chromosome transmission in mitosis and maintenance of normal telomere length YMR094W CTF13 kinetochore protein complex, CBF3, 58 KD subunit YMR104C YPK2 ser/thr protein kinase YMR127C SAS2 involved in silencing at HMR YMR133W REC114 meiotic recombination protein YMR138W CIN4 GTP-binding protein YMR139W RIM11 ser/thr protein kinase YMR167W MLH1 DNA mismatch repair protein YMR168C CEP3 kinetochore protein complex, 71 KD subunit YMR198W CIK1 spindle pole body associated protein YMR199W CLN1 cyclin, G1/S-specific YMR200W ROT1 mutant suppresses TOR2 mutation YMR213W CEF1 required during G2/M transition YMR224C MRE11 DNA repair and meiotic recombination protein YMR262W YMR262W similarity to S.pombe scn1 protein YMR273C ZDS1 involved in negative regulation of cell polarity YMR276W DSK2 ubiquitin-like protein YMR294W JNM1 mitosis protein, involved in nuclear migration YNL001W DOM34 functions in protein translation to promote G1 progression and differentiation YNL007C SIS1 heat shock protein YNL012W SPO1 transcriptional regulator involved in sporulation YNL025C SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YNL053W MSG5 dual-specifity protein phosphatase YNL064C YDJ1 mitochondrial and ER import protein YNL098C RAS2 GTP-binding protein YNL126W SPC98 spindle pole body component YNL153C GIM3 Gim complex component YNL154C YCK2 casein kinase I isoform YNL172W APC1 subunit of anaphase-promoting complex (cyclosome) YNL188W KAR1 cell division control protein YNL192W CHS1 chitin synthase I YNL196C SLZ1 sporulation-specific protein YNL204C SPS18 sporulation-specific zinc-finger protein YNL210W MER1 meiotic recombination protein YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL225C CNM67 involved in cytokinesis YNL242W APG2 required for sporulation YNL246W YNL246W similarity to D.melanogaster SET protein YNL250W RAD50 DNA repair protein YNL262W POL2 DNA-directed DNA polymerase epsilon, catalytic subunit A YNL267W PIK1 phosphatidylinositol 4-kinase YNL271C BNI1 regulator of budding YNL289W PCL1 cyclin, G1/S-specific YNL292W PUS4 pseudouridine synthase YNL298W CLA4 ser/thr protein kinase YNL299W TRF5 nuclear division protein YNL307C MCK1 ser/thr/tyr protein kinase YNL327W EGT2 cell-cycle regulation protein YNR010W CSE2 subunit of RNA polymerase II mediator complex YOL021C DIS3 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YOL069W NUF2 spindle pole body protein YOL076W MDM20 necessary for mitochondrial inheritance and organisation of the actin cytoskeleton YOL080C REX4 strong similarity to X.laevis XPMC2 protein and YGR276c YOL091W SPO21 component of the meiotic plaque, required for formation of the prospore membrane YOL104C NDJ1 meiotic telomere protein YOL115W TRF4 topoisomerase I-related protein YOL145C CTR9 required for G1 cyclin expression YOR005C DNL4 DNA ligase IV YOR026W BUB3 cell cycle arrest protein YOR028C CIN5 transcriptional activator YOR057W SGT1 suppressor of G2 allele of SKP1 YOR058C ASE1 microtubule-associated protein (nonmotor) YOR061W CKA2 casein kinase II alpha' chain YOR149C SMP3 protein kinase C pathway protein YOR156C NFI1 interacts with CDC12P in 2-hybrid assay YOR177C MPC54 meiosis-specific component of the SPB YOR181W LAS17 component of actin cortical patches YOR195W SLK19 involved in control of spindle dynamics together with KAR3P YOR198C BFR1 maintenance of normal ploidy YOR208W PTP2 protein-tyrosine-phosphatase YOR213C SAS5 subunit of the RSC complex YOR217W RFC1 DNA replication factor C, 95 KD subunit YOR231W MKK1 ser/thr protein kinase YOR249C APC5 component of the anaphase-promoting complex YOR257W CDC31 spindle pole body component, centrin YOR265W RBL2 beta-tubulin binding protein YOR272W YTM1 microtubule-interacting protein YOR298W MUM3 required for meiosis YOR349W CIN1 chromosome segregation protein YOR351C MEK1 ser/thr protein kinase YOR361C PRT1 translation initiation factor eIF3 subunit YOR368W RAD17 DNA damage checkpoint control protein YOR372C NDD1 protein required for nuclear division YOR373W NUD1 cell cycle regulatory protein YPL008W CHL1 protein of the DEAH box family YPL018W CTF19 involved in chromosome segregation YPL031C PHO85 cyclin-dependent protein kinase YPL042C SSN3 cyclin-dependent CTD kinase YPL046C ELC1 Elongin C transcription elongation factor YPL121C MEI5 meiotic protein YPL126W NAN1 weak similarity to fruit fly TFIID subunit p85 YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL139C UME1 negative regulator of meiosis YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL153C RAD53 ser/thr/tyr protein kinase YPL155C KIP2 kinesin-related protein YPL174C NIP100 component of the dynactin complex YPL178W CBC2 small subunit of the nuclear cap-binding protein complex CBC YPL194W DDC1 DNA damage checkpoint protein YPL204W HRR25 casein kinase I, ser/thr/tyr protein kinase YPL209C IPL1 ser/thr protein kinase YPL239W YAR1 ankyrin repeat-containing protein YPL240C HSP82 heat shock protein YPL241C CIN2 involved in chromosome segregation YPL242C IQG1 involved in cytokinesis, has similarity to mammalian IQGAP proteins YPL255W BBP1 cell division control protein YPL256C CLN2 cyclin, G1/S-specific YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YPL269W KAR9 cortical protein required for cytoplasmic microtubule orientation and nuclear migration YPR007C SPO69 protein required for meiosis and sporulation YPR019W CDC54 member of the CDC46P/MCM2P/MCM3P family YPR025C CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPR046W MCM16 involved in chromosome segregation YPR082C DIB1 required for mitosis YPR103W PRE2 20S proteasome subunit (beta5) YPR111W DBF20 cell cycle protein kinase related to DBF2P YPR119W CLB2 cyclin, G2/M-specific YPR120C CLB5 cyclin, B-type YPR141C KAR3 kinesin-related protein YPR161C SGV1 ser/thr protein kinase mitotic cell cycle and cell cycle control (352 ORFs) 03.03.01 352 YAL016W TPD3 ser/thr protein phosphatase 2A, regulatory chain A YAL024C LTE1 GDP/GTP exchange factor YAL025C MAK16 nuclear viral propagation protein YAL034W-A MTW1 determining metaphase spindle length YAL040C CLN3 cyclin, G1/S-specific YAL041W CDC24 GTP/GDP exchange factor for CDC42P YAL047C SPC72 STU2P Interactant YAR003W SWD1 similarity to human RB protein binding protein YAR019C CDC15 protein kinase of the MAP kinase kinase kinase family YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBL020W RFT1 nuclear division protein YBL058W SHP1 potential regulatory subunit for GLC7P YBL063W KIP1 kinesin-related protein YBL084C CDC27 subunit of anaphase-promoting complex (cyclosome) YBL088C TEL1 telomere length control protein YBL097W BRN1 functional homologue of human BRRN1 YBL105C PKC1 ser/thr protein kinase YBR079C RPG1 translation initiation factor eIF3 (p110 subunit) YBR087W RFC5 DNA replication factor C, 40 KD subunit YBR107C IML3 weak similarity to N.crassa chitin synthase YBR109C CMD1 calmodulin YBR133C HSL7 adapter in a regulatory pathway that relieves tyrosine phosphorylation of CDC28 YBR135W CKS1 cyclin-dependent kinases regulatory subunit YBR136W MEC1 cell cycle checkpoint protein YBR156C SLI15 Mitotic spindle protein involved in chromosome segregation YBR160W CDC28 cyclin-dependent protein kinase YBR186W PCH2 putative ATPase YBR200W BEM1 bud emergence mediator YBR202W CDC47 cell division control protein YBR211C AME1 actin related protein YBR215W HPC2 cell cycle regulatory protein YBR238C YBR238C strong similarity to general chromatin factor SPT16P YBR243C ALG7 UDP-N-acetylglucosamine-1-phosphate transferase YBR274W CHK1 regulats inhibitory Cdk phosphorylation of PDS1 YBR276C PPS1 protein tyrosine phosphatase YCL004W PGS1 phosphatidylglycerophosphate synthase YCL016C DCC1 part of an alternative RFC complex YCL024W KCC4 kinase coordinate cell cycle progression with the organization of the peripheralcytoskeleton YCL029C BIK1 nuclear fusion protein YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCR002C CDC10 cell division control protein YCR052W RSC6 subunit of the RSC complex YCR086W CSM1 involved in nuclear migration YCR094W CDC50 cell division cycle mutant YDL003W MCD1 Mitotic Chromosome Determinant YDL008W APC11 subunit of the anaphase promoting complex YDL017W CDC7 protein kinase YDL028C MPS1 serine/threonine/tyrosine protein kinase YDL047W SIT4 ser/thr protein phosphatase YDL056W MBP1 transcription factor, subunit of the MBF factor YDL064W UBC9 E2 ubiquitin-conjugating enzyme YDL108W KIN28 cyclin-dependent ser/thr protein kinase YDL126C CDC48 microsomal protein of CDC48/PAS1/SEC18 family of ATPases YDL127W PCL2 cyclin, G1/S-specific YDL132W CDC53 controls G1/S transition YDL134C PPH21 protein ser/thr phosphatase PP2A-1 YDL155W CLB3 cyclin, G2/M-specific YDL165W CDC36 transcription factor YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL220C CDC13 cell division control protein YDL225W SHS1 septin YDL226C GCS1 ADP-ribosylation factor GTPase-activating protein (ARF-GAP) YDR022C CIS1 involved in suppression of CIK1 mutation YDR052C DBF4 regulatory subunit for CDC7P protein kinase YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR082W STN1 involved in telomere length regulation YDR099W BMH2 suppressor of clathrin deficiency YDR113C PDS1 cell cycle regulator YDR118W APC4 subunit of the anaphase promoting complex YDR130C FIN1 weak similarity to sea urchin myosin heavy chain YDR137W RGP1 reduced growth phenotype protein YDR150W NUM1 nuclear migration protein YDR168W CDC37 cell division control protein YDR172W SUP35 eukaryotic peptide chain release factor GTP-binding subunit YDR180W SCC2 involved in sister chromatid cohesion YDR182W CDC1 cell division control protein YDR207C UME6 negative transcriptional regulator YDR217C RAD9 DNA repair checkpoint protein YDR254W CHL4 chromosome segregation protein YDR285W ZIP1 synaptonemal complex protein YDR293C SSD1 involved in the tolerance to high concentration of Ca2+ YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR356W NUF1 spindle pole body component YDR363W-A SEM1 regulator of exocytosis and pseudohyphal differentiation YDR364C CDC40 cell division control protein YDR416W SYF1 synthetic lethal with CDC40 YDR440W DOT1 putative ATPase YDR457W TOM1 E3 ubiqitin ligase required for G2/M transition YDR488C PAC11 required in the absence of CIN8P YDR499W LCD1 cell cycle checkpoint protein YDR507C GIN4 ser/thr protein kinase YEL037C RAD23 nucleotide excision repair protein (ubiquitin-like protein) YEL061C CIN8 kinesin-related protein YER007W PAC2 involved in the stabilization of microtubles YER016W BIM1 binding to microtubules YER066W YER066W strong similarity to cell division control protein CDC4P YER075C PTP3 protein tyrosine phosphatase YER111C SWI4 transcription factor YER122C GLO3 zinc finger protein YER123W YCK3 casein kinase, isoform 3 YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER155C BEM2 GTPase-activating protein YER173W RAD24 cell cycle checkpoint protein YER177W BMH1 14-3-3 protein involved in rapamycin-sensitive signalling YER179W DMC1 meiosis-specific protein YFL008W SMC1 chromosome segregation protein YFL009W CDC4 cell division control protein YFL017C GNA1 essential acetyltransferase YFL029C CAK1 cdk-activating protein kinase YFL037W TUB2 beta-tubulin YFL039C ACT1 actin YFR027W ECO1 involved in sister chromatid cohesion during replication YFR028C CDC14 dual specificity phosphatase YFR031C SMC2 chromosome segregation protein YFR036W CDC26 subunit of anaphase-promoting complex (cyclosome) YFR037C RSC8 subunit of the RSC complex YFR040W SAP155 SIT4P-associated protein YFR052W RPN12 26S proteasome regulatory subunit YGL003C CDH1 substrate-specific activator of APC-dependent proteolysis YGL048C RPT6 26S proteasome regulatory subunit YGL056C SDS23 strong similarity to pombe SDS23 YGL073W HSF1 heat shock transcription factor YGL075C MPS2 Protein of the nuclear envelope/endoplasmic reticulum required for spindle pole body assembly and normal chromosome segregation YGL086W MAD1 spindle assembly checkpoint protein YGL116W CDC20 cell division control protein YGL155W CDC43 geranylgeranyltransferase beta subunit YGL158W RCK1 ser/thr protein kinase YGL173C KEM1 multifunctional nuclease YGL178W MPT5 multicopy suppressor of POP2 YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL190C CDC55 ser/thr phosphatase 2A regulatory subunit B YGL207W SPT16 general chromatin factor YGL215W CLG1 cyclin-like protein YGL216W KIP3 kinesin-related protein required for nuclear migration YGL229C SAP4 SIT4P-associated protein YGL240W DOC1 component of the anaphase promoting complex YGR023W MTL1 potential cell wall stres sensor YGR029W ERV1 mitochondrial biogenesis and regulation of cell cycle YGR044C RME1 zinc-finger transcription factor YGR049W SCM4 CDC4 suppressor YGR078C PAC10 GIM4 - Gim complex component YGR092W DBF2 ser/thr protein kinase related to DBF20P YGR098C ESP1 required for sister chromatid separation YGR108W CLB1 cyclin, G2/M-specific YGR109C CLB6 cyclin, B-type YGR132C PHB1 prohibitin, antiproliferative protein YGR140W CBF2 kinetochore protein complex CBF3, 110 KD subunit YGR179C OKP1 component of centromere/kinetochore-associated protein network YGR188C BUB1 ser/thr protein kinase YGR209C TRX2 thioredoxin II YGR230W BNS1 Bypasses Need for SPO12P YGR231C PHB2 Prohibitin YGR245C SDA1 required for normal organization of the actin cytoskeleton; required for passage through Start YHR013C ARD1 protein N-acetyltransferase subunit YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR079C-A SAE3 meiosis specific protein YHR101C BIG1 big cells phenotype YHR102W KIC1 ser/thr protein kinase that interacts with CDC31P YHR107C CDC12 septin YHR119W SET1 involved in chromatin-mediated gene regulation YHR129C ARP1 centractin YHR165C PRP8 U5 snRNP protein, pre-mRNA splicing factor YHR166C CDC23 subunit of anaphase-promoting complex (cyclosome) YHR172W SPC97 spindle pole body component YHR205W SCH9 serine/threonine protein kinase involved in stress response and nutrient-sensing signaling pathway YHR206W SKN7 transcription factor with similarity to HSF1P YHR208W BAT1 branched chain amino acid aminotransferase, mitochondrial YIL026C IRR1 essential protein YIL031W ULP2 SMT3P-specific protease, degrades conjugated ubiquitin-like protein SMT3P YIL035C CKA1 casein kinase II, catalytic alpha chain YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL095W PRK1 serine/threonine protein kinase involved in regulation of actin cytoskeleton organization YIL106W MOB1 required for completion of mitosis and maintenance of ploidy YIL123W SIM1 involved in cell cycle regulation and aging YIL126W STH1 subunit of the RSC complex YIL150C DNA43 required for S-phase initiation or completion YIR024C GIF1 G1 Factor needed for normal G1 phase YJL005W CYR1 adenylate cyclase YJL013C MAD3 spindle-assembly checkpoint protein YJL030W MAD2 spindle-assembly checkpoint protein YJL034W KAR2 nuclear fusion protein YJL074C SMC3 required for structural maintenance of chromosomes YJL080C SCP160 required for maintenance of exact ploidy YJL090C DPB11 involved in DNA replication and S-phase checkpoint YJL095W BCK1 ser/thr protein kinase of the MEKK family YJL098W SAP185 SIT4P-associating protein YJL106W IME2 ser/thr protein kinase YJL141C YAK1 ser/thr protein kinase YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJL187C SWE1 ser/tyr dual-specifity protein kinase YJL194W CDC6 cell division control protein YJR053W BFA1 spindle assembly checkpoint protein YJR060W CBF1 kinetochore protein YJR066W TOR1 phosphatidylinositol 3-kinase YJR068W RFC2 DNA replication factor C, 41 KD subunit YJR076C CDC11 septin YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR091C JSN1 suppresses the high-temperature lethality of TUB2-150 YJR112W NNF1 nuclear envelope protein YJR140C HIR3 involved in cell cycle regulation of histone transcription YKL017C HCS1 DNA helicase A YKL022C CDC16 subunit of anaphase-promoting complex (cyclosome) YKL042W SPC42 spindle pole body component YKL048C ELM1 ser/thr-specific protein kinase YKL049C CSE4 component of the core centromere YKL089W MIF2 required for normal chromosome segregation and spindle integrity YKL101W HSL1 ser/thr protein kinase, coupling septin ring assembly to cell cycle progression YKL145W RPT1 26S proteasome regulatory subunit YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL179C YKL179C similarity to NUF1P YKL193C SDS22 regulatory subunit for the mitotic function of type I protein phosphatase YKL203C TOR2 phosphatidylinositol 3-kinase YKR028W SAP190 SIT4P-associated protein YKR042W UTH1 involved in the aging process YKR048C NAP1 nucleosome assembly protein I YKR054C DYN1 dynein heavy chain, cytosolic YKR063C LAS1 involved in cell morphogenesis, cytoskeletal regulation and bud formation YKR072C SIS2 involved in cell cycle-specific gene expression YLL003W SFI1 similarity to Xenopus laevis XCAP-C YLL016W SDC25 GDP/GTP exchange factor (GEF) YLL017W YLL017W maybe part of SCD25 YLR043C TRX1 thioredoxin I YLR075W RPL10 60S large subunit ribosomal protein YLR079W SIC1 p40 inhibitor of CDC28P-Clb protein kinase complex YLR102C APC9 subunit of the Anaphase Promoting Complex YLR103C CDC45 required for minichromosome maintenance and initiation of chromosomal DNA replication YLR117C CLF1 strong similarity to Drosophila putative cell cycle control protein crn YLR127C APC2 component of the anaphase promoting complex YLR129W DIP2 DOM34P-interacting protein YLR175W CBF5 putative rRNA pseuduridine synthase YLR178C TFS1 CDC25-dependent nutrient- and ammonia-response cell-cycle regulator YLR179C YLR179C similarity to TFS1P YLR182W SWI6 transcription factor YLR210W CLB4 cyclin, G2/M-specific YLR212C TUB4 gamma tubulin YLR215C CDC123 strong similarity to rat cell cycle progression related D123 protein YLR226W BUR2 divergent CDK-cyclin complex YLR229C CDC42 GTP-binding protein of RAS superfamily YLR234W TOP3 DNA topoisomerase III YLR248W RCK2 Ca/calmodulin-dependent ser/thr protein kinase YLR274W CDC46 cell division control protein YLR288C MEC3 G2-specific checkpoint protein YLR299W ECM38 gamma-glutamyltransferase, involved in glutathione synthesis YLR305C STT4 phosphatidylinositol-4-kinase YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR314C CDC3 cell division control protein YLR321C SFH1 subunit of the RSC complex YLR332W MID2 mating process protein YLR356W YLR356W similarity to SCM4 protein YLR403W SFP1 zinc finger protein YML031W NDC1 nuclear envelope protein YML064C TEM1 GTP-binding protein of the RAS superfamily YML085C TUB1 alpha-1 tubulin YML104C MDM1 intermediate filament protein YML109W ZDS2 multicopy suppressor of SIN4 YML115C VAN1 vanadate resistance protein YML124C TUB3 alpha-3 tubulin YMR001C CDC5 involved in regulation of DNA replication YMR028W TAP42 component of the Tor signaling pathway YMR036C MIH1 M-phase inducing protein tyrosine phosphatase YMR043W MCM1 transcription factor of the MADS box family YMR052W FAR3 involved in pheromone-mediated cell cycle arrest YMR055C BUB2 cell cycle arrest protein YMR078C CTF18 required for accurate chromosome transmission in mitosis and maintenance of normal telomere length YMR094W CTF13 kinetochore protein complex, CBF3, 58 KD subunit YMR104C YPK2 ser/thr protein kinase YMR127C SAS2 involved in silencing at HMR YMR138W CIN4 GTP-binding protein YMR168C CEP3 kinetochore protein complex, 71 KD subunit YMR198W CIK1 spindle pole body associated protein YMR199W CLN1 cyclin, G1/S-specific YMR200W ROT1 mutant suppresses TOR2 mutation YMR213W CEF1 required during G2/M transition YMR224C MRE11 DNA repair and meiotic recombination protein YMR262W YMR262W similarity to S.pombe scn1 protein YMR273C ZDS1 involved in negative regulation of cell polarity YMR276W DSK2 ubiquitin-like protein YMR294W JNM1 mitosis protein, involved in nuclear migration YNL001W DOM34 functions in protein translation to promote G1 progression and differentiation YNL007C SIS1 heat shock protein YNL012W SPO1 transcriptional regulator involved in sporulation YNL053W MSG5 dual-specifity protein phosphatase YNL064C YDJ1 mitochondrial and ER import protein YNL098C RAS2 GTP-binding protein YNL126W SPC98 spindle pole body component YNL153C GIM3 Gim complex component YNL172W APC1 subunit of anaphase-promoting complex (cyclosome) YNL188W KAR1 cell division control protein YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL225C CNM67 involved in cytokinesis YNL246W YNL246W similarity to D.melanogaster SET protein YNL262W POL2 DNA-directed DNA polymerase epsilon, catalytic subunit A YNL289W PCL1 cyclin, G1/S-specific YNL292W PUS4 pseudouridine synthase YNL299W TRF5 nuclear division protein YNL307C MCK1 ser/thr/tyr protein kinase YNL327W EGT2 cell-cycle regulation protein YNR010W CSE2 subunit of RNA polymerase II mediator complex YOL021C DIS3 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YOL069W NUF2 spindle pole body protein YOL076W MDM20 necessary for mitochondrial inheritance and organisation of the actin cytoskeleton YOL080C REX4 strong similarity to X.laevis XPMC2 protein and YGR276c YOL115W TRF4 topoisomerase I-related protein YOL145C CTR9 required for G1 cyclin expression YOR026W BUB3 cell cycle arrest protein YOR028C CIN5 transcriptional activator YOR057W SGT1 suppressor of G2 allele of SKP1 YOR058C ASE1 microtubule-associated protein (nonmotor) YOR061W CKA2 casein kinase II alpha' chain YOR149C SMP3 protein kinase C pathway protein YOR156C NFI1 interacts with CDC12P in 2-hybrid assay YOR195W SLK19 involved in control of spindle dynamics together with KAR3P YOR198C BFR1 maintenance of normal ploidy YOR213C SAS5 subunit of the RSC complex YOR217W RFC1 DNA replication factor C, 95 KD subunit YOR231W MKK1 ser/thr protein kinase YOR249C APC5 component of the anaphase-promoting complex YOR257W CDC31 spindle pole body component, centrin YOR272W YTM1 microtubule-interacting protein YOR349W CIN1 chromosome segregation protein YOR361C PRT1 translation initiation factor eIF3 subunit YOR368W RAD17 DNA damage checkpoint control protein YOR372C NDD1 protein required for nuclear division YOR373W NUD1 cell cycle regulatory protein YPL008W CHL1 protein of the DEAH box family YPL018W CTF19 involved in chromosome segregation YPL031C PHO85 cyclin-dependent protein kinase YPL126W NAN1 weak similarity to fruit fly TFIID subunit p85 YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL153C RAD53 ser/thr/tyr protein kinase YPL155C KIP2 kinesin-related protein YPL174C NIP100 component of the dynactin complex YPL178W CBC2 small subunit of the nuclear cap-binding protein complex CBC YPL194W DDC1 DNA damage checkpoint protein YPL209C IPL1 ser/thr protein kinase YPL239W YAR1 ankyrin repeat-containing protein YPL241C CIN2 involved in chromosome segregation YPL255W BBP1 cell division control protein YPL256C CLN2 cyclin, G1/S-specific YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YPL269W KAR9 cortical protein required for cytoplasmic microtubule orientation and nuclear migration YPR019W CDC54 member of the CDC46P/MCM2P/MCM3P family YPR025C CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPR046W MCM16 involved in chromosome segregation YPR082C DIB1 required for mitosis YPR103W PRE2 20S proteasome subunit (beta5) YPR111W DBF20 cell cycle protein kinase related to DBF2P YPR119W CLB2 cyclin, G2/M-specific YPR120C CLB5 cyclin, B-type YPR141C KAR3 kinesin-related protein YPR161C SGV1 ser/thr protein kinase cell cycle checkpoints (checkpoints of morphogenesis, DNA-damage,-replication, mitotic phase and spindle) (27 ORFs) 03.03.01.03 27 YBL088C TEL1 telomere length control protein YBR087W RFC5 DNA replication factor C, 40 KD subunit YBR136W MEC1 cell cycle checkpoint protein YBR274W CHK1 regulats inhibitory Cdk phosphorylation of PDS1 YDR099W BMH2 suppressor of clathrin deficiency YDR113C PDS1 cell cycle regulator YDR217C RAD9 DNA repair checkpoint protein YDR499W LCD1 cell cycle checkpoint protein YER016W BIM1 binding to microtubules YER173W RAD24 cell cycle checkpoint protein YER177W BMH1 14-3-3 protein involved in rapamycin-sensitive signalling YGL086W MAD1 spindle assembly checkpoint protein YGR140W CBF2 kinetochore protein complex CBF3, 110 KD subunit YGR188C BUB1 ser/thr protein kinase YJL013C MAD3 spindle-assembly checkpoint protein YJL030W MAD2 spindle-assembly checkpoint protein YJL090C DPB11 involved in DNA replication and S-phase checkpoint YJL187C SWE1 ser/tyr dual-specifity protein kinase YJR053W BFA1 spindle assembly checkpoint protein YJR068W RFC2 DNA replication factor C, 41 KD subunit YLR288C MEC3 G2-specific checkpoint protein YMR055C BUB2 cell cycle arrest protein YNL262W POL2 DNA-directed DNA polymerase epsilon, catalytic subunit A YOR026W BUB3 cell cycle arrest protein YOR368W RAD17 DNA damage checkpoint control protein YPL153C RAD53 ser/thr/tyr protein kinase YPL194W DDC1 DNA damage checkpoint protein meiosis (104 ORFs) 03.03.02 104 YAL009W SPO7 meiotic protein YBL058W SHP1 potential regulatory subunit for GLC7P YBR045C GIP1 GLC7-interacting protein YBR057C MUM2 meiotic protein YBR073W RDH54 required for mitotic diploid-specific recombination and repair and meiosis YBR078W ECM33 involved in cell wall biogenesis and architecture YBR136W MEC1 cell cycle checkpoint protein YCL048W YCL048W strong similarity to sporulation-specific protein SPS2P YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCR086W CSM1 involved in nuclear migration YDL017W CDC7 protein kinase YDL028C MPS1 serine/threonine/tyrosine protein kinase YDL114W YDL114W weak similarity to Rhizobium nodulation protein nodG YDL154W MSH5 meiosis-specific protein YDL220C CDC13 cell division control protein YDR004W RAD57 DNA repair protein YDR055W PST1 strong similarity to SPS2 protein YDR076W RAD55 DNA repair protein YDR108W GSG1 sporulation specific protein YDR207C UME6 negative transcriptional regulator YDR218C SPR28 septin-related sporulation protein YDR260C SWM1 developmentally regulated gene, is required for spore wall assembly YDR285W ZIP1 synaptonemal complex protein YDR369C XRS2 DNA repair protein YDR522C SPS2 sporulation-specific protein YDR523C SPS1 ser/thr protein kinase YER044C-A MEI4 meiosis-specific protein YER095W RAD51 DNA repair protein YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER179W DMC1 meiosis-specific protein YER180C ISC10 meiosis-specific protein YFL003C MSH4 meiosis-specific protein YFL037W TUB2 beta-tubulin YGL033W HOP2 required for pairing of homologous chromosomes YGL090W LIF1 DNA ligase IV interacting factor YGL163C RAD54 DNA-dependent ATPase of the SNF2P family YGL175C SAE2 meiotic recombination protein YGL213C SKI8 antiviral protein of the beta-transducin (WD-40) repeat family YGL249W ZIP2 required for meiotic recombination and disjunction YGR044C RME1 zinc-finger transcription factor YGR109C CLB6 cyclin, B-type YGR253C PUP2 20S proteasome subunit(alpha5) YGR258C RAD2 structure-specific nuclease of the nucleotide excision repairosome YHL022C SPO11 catalytic subunit of the meiotic double strand break transesterase YHL024W RIM4 No sporulation YHL027W RIM101 meiotic regulatory protein YHR004C NEM1 required for nuclear morphology YHR014W SPO13 meiosis-specific protein YHR079C-A SAE3 meiosis specific protein YHR086W NAM8 meiotic recombination protein YHR124W NDT80 meiosis-specific protein YHR152W SPO12 sporulation protein YHR153C SPO16 sporulation protein YHR157W REC104 meiosis-specific protein YHR184W SSP1 essential for meiosis and spore formation YIL072W HOP1 meiosis-specific protein YIR008C PRI1 DNA-directed DNA polymerase alpha 48kDa subunit (DNA primase) YIR026C YVH1 protein tyrosine phosphatase YJL106W IME2 ser/thr protein kinase YJL146W IDS2 IME2-dependent signaling protein YJR021C REC107 meiotic recombination protein YJR094C IME1 transcription factor required for sporulation YKL017C HCS1 DNA helicase A YKL112W ABF1 ARS-binding factor YKR031C SPO14 phospholipase D YKR046C YKR046C hypothetical protein YLR129W DIP2 DOM34P-interacting protein YLR234W TOP3 DNA topoisomerase III YLR263W RED1 meiosis-specific protein YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR329W REC102 meiotic recombination protein YMR076C PDS5 precocious dissociation of sister chromatids YMR133W REC114 meiotic recombination protein YMR139W RIM11 ser/thr protein kinase YMR167W MLH1 DNA mismatch repair protein YMR224C MRE11 DNA repair and meiotic recombination protein YNL025C SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YNL196C SLZ1 sporulation-specific protein YNL204C SPS18 sporulation-specific zinc-finger protein YNL210W MER1 meiotic recombination protein YNL242W APG2 required for sporulation YNL250W RAD50 DNA repair protein YNL307C MCK1 ser/thr/tyr protein kinase YOL091W SPO21 component of the meiotic plaque, required for formation of the prospore membrane YOL104C NDJ1 meiotic telomere protein YOR005C DNL4 DNA ligase IV YOR177C MPC54 meiosis-specific component of the SPB YOR198C BFR1 maintenance of normal ploidy YOR208W PTP2 protein-tyrosine-phosphatase YOR265W RBL2 beta-tubulin binding protein YOR298W MUM3 required for meiosis YOR351C MEK1 ser/thr protein kinase YOR368W RAD17 DNA damage checkpoint control protein YPL042C SSN3 cyclin-dependent CTD kinase YPL046C ELC1 Elongin C transcription elongation factor YPL121C MEI5 meiotic protein YPL139C UME1 negative regulator of meiosis YPL204W HRR25 casein kinase I, ser/thr/tyr protein kinase YPL240C HSP82 heat shock protein YPL255W BBP1 cell division control protein YPR007C SPO69 protein required for meiosis and sporulation YPR103W PRE2 20S proteasome subunit (beta5) YPR120C CLB5 cyclin, B-type YPR141C KAR3 kinesin-related protein cytokinesis (cell division) (35 ORFs) 03.03.03 35 YAL016W TPD3 ser/thr protein phosphatase 2A, regulatory chain A YAL029C MYO4 myosin heavy chain, unconventional (class V) isoform YBL079W NUP170 nuclear pore protein YCR002C CDC10 cell division control protein YCR057C PWP2 periodic tryptophan protein YDL029W ARP2 actin-like protein YDL225W SHS1 septin YDR284C DPP1 diacylglycerol pyrophosphate phosphatase YDR507C GIN4 ser/thr protein kinase YGL056C SDS23 strong similarity to pombe SDS23 YGL061C DUO1 essential mitotic spindle protein YGL106W MLC1 MYO2P light chain YGL190C CDC55 ser/thr phosphatase 2A regulatory subunit B YGR113W DAM1 essential mitotic spindle pole protein YHR023W MYO1 myosin-1 isoform (type II myosin) heavy chain YHR107C CDC12 septin YHR135C YCK1 casein kinase I isoform YJR076C CDC11 septin YLR131C ACE2 metallothionein expression activator YLR286C CTS1 endochitinase YLR314C CDC3 cell division control protein YMR032W HOF1 involved in cytokinesis YNL154C YCK2 casein kinase I isoform YNL192W CHS1 chitin synthase I YNL225C CNM67 involved in cytokinesis YNL267W PIK1 phosphatidylinositol 4-kinase YNL271C BNI1 regulator of budding YNL298W CLA4 ser/thr protein kinase YNL327W EGT2 cell-cycle regulation protein YOR156C NFI1 interacts with CDC12P in 2-hybrid assay YOR181W LAS17 component of actin cortical patches YOR372C NDD1 protein required for nuclear division YPL242C IQG1 involved in cytokinesis, has similarity to mammalian IQGAP proteins YPL255W BBP1 cell division control protein YPL269W KAR9 cortical protein required for cytoplasmic microtubule orientation and nuclear migration nuclear and chromosomal cycle (3 ORFs) 03.03.04 3 YDR325W YCG1 Yeast Condensin G YJR089W BIR1 member of the inhibitor of apoptosis family, participate in chromosome segregation events YJR135C MCM22 required for maintenance of chromosomes and minichromosomes chromosome condensation (1 ORF) 03.03.04.03 1 YDR325W YCG1 Yeast Condensin G chromosome segregation (2 ORFs) 03.03.04.05 2 YJR089W BIR1 member of the inhibitor of apoptosis family, participate in chromosome segregation events YJR135C MCM22 required for maintenance of chromosomes and minichromosomes other cell division and DNA synthesis activities (6 ORFs) 03.99 6 YBR138C HDR1 High-Dosage Reductional segregation defective YFL034C-B MOB2 required for maintenance in ploidy YJR138W IML1 similarity to C.elegans hypothetical protein T08A11.1 YMR096W SNZ1 stationary phase protein YOL110W SHR5 RAS suppressor YOR101W RAS1 GTP-binding protein TRANSCRIPTION (771 ORFs) 04 771 YAL001C TFC3 TFIIIC (transcription initiation factor) subunit, 138 kD YAL016W TPD3 ser/thr protein phosphatase 2A, regulatory chain A YAL021C CCR4 transcriptional regulator YAL032C PRP45 pre-mRNA splicing factor YAL033W POP5 required for processing of tRNAs and rRNAs YAL043C PTA1 pre-tRNA processing protein / PF I subunit YAL051W OAF1 peroxisome proliferating transcription factor YAR003W SWD1 similarity to human RB protein binding protein YAR008W SEN34 tRNA splicing endonuclease gamma subunit YBL002W HTB2 histone H2B.2 YBL003C HTA2 histone H2A.2 YBL005W PDR3 pleiotropic drug resistance regulatory protein YBL008W HIR1 histone transcription regulator YBL013W FMT1 Methionyl-tRNA Transformylase YBL014C RRN6 RNA polymerase I specific transcription initiation factor YBL018C POP8 required for processing of tRNAs and rRNAs YBL021C HAP3 CCAAT-binding factor subunit YBL022C PIM1 ATP-dependent protease, mitochondrial YBL024W NCL1 tRNA (cytosine-5-)-methyltransferase YBL025W RRN10 RNA polymerase I-specific transcription initiation factor YBL026W LSM2 Sm-like (Lsm) protein YBL052C SAS3 silencing protein YBL054W YBL054W weak similarity to transforming protein (B-myb) YBL066C SEF1 putative transcription factor YBL074C AAR2 A1 cistron splicing factor YBL093C ROX3 transcription factor YBL103C RTG3 bHLH/zip transcription factor that regulates CIT2 gene expression YBR009C HHF1 histone H4 YBR010W HHT1 histone H3 YBR020W GAL1 galactokinase YBR026C (MRF1) mitochondrial respiratory function protein YBR033W YBR033W weak similarity to transcription factors YBR045C GIP1 GLC7-interacting protein YBR049C REB1 transcription factor YBR055C PRP6 snRNP(U4/U6)-associated splicing factor YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR061C YBR061C similarity to E.coli ftsJ protein YBR081C SPT7 involved in alteration of transcription start site selection YBR083W TEC1 Ty transcription activator YBR103W SIF2 SIR4P interacting protein YBR112C CYC8 general repressor of transcription YBR119W MUD1 U1 snRNP-specific A protein YBR120C CBP6 apo-cytochrome B pre-mRNA processing protein YBR123C TFC1 TFIIIC (transcription initiation factor) subunit, 95 kD YBR142W MAK5 ATP-dependent RNA helicase YBR150C TBS1 weak similarity to transcription factors YBR152W SPP381 Suppressor of Pre-mRNA Processing mutant YBR154C RPB5 DNA-directed RNA polymerase I, II, III 25 KD subunit YBR167C POP7 nuclear RNase P subunit YBR182C SMP1 MADS-box transcription factor YBR188C NTC20 splicing factor YBR193C MED8 transcriptional regulation mediator YBR198C TAF90 TFIID and SAGA subunit YBR212W NGR1 glucose-repressible RNA-binding protein YBR215W HPC2 cell cycle regulatory protein YBR233W PBP2 PAB1 binding protein YBR236C ABD1 mRNA cap methyltransferase YBR237W PRP5 pre-mRNA processing RNA-helicase YBR239C YBR239C weak similarity to transcription factor PUT3P YBR240C THI2 regulator of the thiamine biosynthetic genes YBR245C ISW1 strong similarity to D.melanogaster iswi protein YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR257W POP4 involved in processing of tRNAs and rRNAs YBR275C RIF1 RAP1-interacting factor 1 YBR279W PAF1 DNA-directed RNA polymerase II regulator YBR289W SNF5 component of SWI/SNF transcription activator complex YBR297W MAL33 maltose fermentation regulatory protein YCL031C RRP7 involved in pre-rRNA processing and ribosome assembly YCL033C YCL033C similarity to M.capricolum transcription repressor YCL037C SRO9 La motif-containing proteins that modulate mRNA translation YCL054W SPB1 required for ribosome synthesis, putative methylase YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCL066W HMLALPHA1 mating type regulatory protein, silenced copy at HML YCR004C YCP4 strong similarity to S. pombe protein obr1 YCR018C SRD1 nucleolar protein YCR020C PET18 similarity to regulatory protein YCR035C RRP43 rRNA processing protein YCR039C MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040W MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCR042C TSM1 component of TFIID complex YCR052W RSC6 subunit of the RSC complex YCR065W HCM1 transcription factor YCR073W-A SOL2 multicopy suppressor of LOS1-1 YCR077C PAT1 topoisomerase II-associated protein YCR081W SRB8 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YCR084C TUP1 general transcription repressor YCR087C-A YCR087C-A similarity to S. pombe SPBC215.06c putative nucleic acid-binding protein YCR093W CDC39 nuclear protein YCR106W YCR106W similarity to transcription factor YDL005C MED2 transcriptional regulation mediator YDL014W NOP1 fibrillarin YDL030W PRP9 pre-mRNA splicing factor (snRNA-associated protein) YDL031W DBP10 putative RNA helicase involved in ribosome biogenesis YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL043C PRP11 pre-mRNA splicing factor YDL044C MTF2 mitochondrial protein involved in mRNA splicing and protein synthesis YDL048C STP4 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YDL051W LHP1 RNA binding protein YDL056W MBP1 transcription factor, subunit of the MBF factor YDL070W BDF2 similarity to bromodomain protein BDF1P YDL080C THI3 positive regulation factor of thiamin metabolism YDL084W SUB2 probably involved in pre-mRNA splicing YDL087C LUC7 yeast U1 snRNP protein with a role in 5' splice site recognition YDL098C SNU23 Putative RNA binding zinc finger protein YDL106C PHO2 homeodomain protein YDL108W KIN28 cyclin-dependent ser/thr protein kinase YDL111C RRP42 rRNA processing protein YDL112W TRM3 tRNA (guanosine-2'-O-)-methyltransferase YDL140C RPO21 DNA-directed RNA polymerase II, 215 KD subunit YDL150W RPC53 DNA-directed RNA polymerase III, 47 KD subunit YDL153C SAS10 involved in silencing YDL160C DHH1 putative RNA helicase of the DEAD box family YDL165W CDC36 transcription factor YDL170W UGA3 transcriptional activator for GABA catabolic genes YDL197C ASF2 anti-silencing protein YDL207W GLE1 RNA export mediator YDL208W NHP2 nucleolar rRNA processing protein YDL220C CDC13 cell division control protein YDR002W YRB1 ran-specific GTPase-activating protein YDR006C SOK1 high copy suppressor of a cyclic AMP-dependent protein kinase mutant YDR009W GAL3 galactokinase YDR017C KCS1 potential transcription factor of the BZIP type YDR021W FAL1 involved in maturation of 18S rRNA YDR026C YDR026C strong similarity to DNA-binding protein REB1P YDR028C REG1 regulatory subunit for protein phosphatase GLC7P YDR034C LYS14 transcriptional activator of lysine pathway genes YDR043C NRG1 transcriptional repressor for glucose repression of STA1 gene expression YDR045C RPC11 RNA polymerase III subunit C11, required for RNA cleavage activity and transcription termination YDR073W SNF11 component of SWI/SNF transcription activator complex YDR083W RRP8 protein involved in cleavage at site A2 in pre-rRNA in the pathway of ribosomal RNA processing YDR087C RRP1 involved in processing rRNA precursor species to mature rRNAs YDR088C SLU7 pre-mRNA splicing factor affecting 3' splice site choice YDR120C TRM1 N2,N2-dimethylguanine tRNA methyltransferase YDR121W DPB4 DNA polymerase II (epsilon) 4th subunit YDR123C INO2 basic helix-loop-helix (BHLH) transcription factor YDR138W HPR1 hyperrecombination protein related to TOP1P YDR145W TAF61 TFIID and SAGA subunit YDR146C SWI5 transcription factor YDR156W RPA14 DNA-directed RNA polymerase I, A14 subunit YDR159W SAC3 leucine permease transcriptional regulator YDR160W SSY1 transcriptional regulator of several transporter genes YDR167W TAF25 TFIID and SAGA subunit YDR169C STB3 SIN3 protein-binding protein YDR173C ARG82 arginine metabolism transcription factor YDR176W NGG1 general transcriptional adaptor or co-activator YDR190C RVB1 RUVB-like protein YDR191W HST4 member of the SIR2P family of putative NAD-dependent histone deacetylases YDR192C NUP42 nuclear pore protein YDR194C MSS116 RNA helicase of the DEAD box family, mitochondrial YDR195W REF2 RNA 3'-end formation protein YDR207C UME6 negative transcriptional regulator YDR213W UPC2 regulatory protein involved in control of sterol uptake YDR216W ADR1 zinc-finger transcription factor YDR217C RAD9 DNA repair checkpoint protein YDR224C HTB1 histone H2B YDR225W HTA1 histone H2A YDR227W SIR4 silencing regulatory and DNA-repair protein YDR228C PCF11 component of pre-mRNA 3'-end processing factor CF I YDR235W PRP42 U1 snRNP associated protein, required for pre-mRNA splicing YDR240C SNU56 U1 snRNA protein, no counterpart in mammalian snRNP YDR243C PRP28 pre-mRNA splicing factor RNA helicase of DEAD box family YDR252W BTT1 alternate beta subunit of the nascent polypeptide-associated complex YDR253C MET32 transcriptional regulator of sulfur amino acid metabolism YDR257C RMS1 regulatory protein YDR259C YAP6 transcription factor, of a fungal-specific family of bzip proteins YDR280W RRP45 rRNA processing protein YDR301W CFT1 pre-mRNA 3'-end processing factor CF II YDR303C RSC3 similarity to transcriptional regulator proteins YDR308C SRB7 DNA-directed RNA polymerase II holoenzyme and kornberg's mediator (SRB) subcomplex subunit YDR310C SUM1 suppressor of SIR mutations YDR311W TFB1 TFIIH subunit (transcription initiation factor), 75 kD YDR334W SWR1 DEAH-box protein, putative RNA helicase YDR362C TFC6 TFIIIC (transcription initiation factor) subunit, 91 kD YDR363W ESC2 involved in silencing YDR378C LSM6 Sm-like (Lsm) protein YDR381W YRA1 RNA annealing protein YDR390C UBA2 E1-like (ubiquitin-activating) enzyme YDR392W SPT3 general transcriptional adaptor or co-activator YDR395W SXM1 putative beta-karyopherin YDR397C NCB2 functional homolog of human NC2beta/Dr1 YDR404C RPB7 DNA-directed RNA polymerase II, 19 KD subunit YDR416W SYF1 synthetic lethal with CDC40 YDR421W ARO80 positive transcription regulator of ARO9 and ARO10 YDR423C CAD1 transcriptional activator YDR432W NPL3 nucleolar protein YDR439W LRS4 involved in rDNA silencing YDR443C SSN2 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDR448W ADA2 general transcriptional adaptor or co-activator YDR451C YHP1 strong similarity to YOX1P YDR460W TFB3 TFIIH subunit (transcription/repair factor) YDR463W STP1 pre-tRNA splicing protein, transcription factor YDR464W SPP41 negative regulator of PRP3 and PRP4 gene expression YDR473C PRP3 essential splicing factor YDR478W SNM1 RNA binding protein of RNase MRP YEL009C GCN4 transcriptional activator of amino acid biosynthetic genes YEL026W SNU13 component of the U4/U6.U5 snRNP YEL056W HAT2 subunit of the major yeast histone acetyltransferase YER013W PRP22 pre-mRNA splicing factor YER022W SRB4 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YER027C GAL83 glucose repression protein YER028C YER028C similarity to MIG1P YER029C SMB1 associated with U1 snRNP as part of the Sm-core that is common to all spliceosomal snRNPs YER032W FIR1 interacts with the poly(A) polymerase in the two hybrid system YER040W GLN3 transcription factor for positive nitrogen regulation YER045C ACA1 ATF/CREB activator YER068W MOT2 transcriptional repressor YER088C DOT6 involved in derepression of telomeric silencing YER107C GLE2 required for nuclear pore complex structure and function YER109C FLO8 required for diploid filamentous growth YER111C SWI4 transcription factor YER112W LSM4 Sm-like (Lsm) protein YER116C SLX8 subunit of HEX3P-SLX8P complex, required for cell growth in the absence of SGS1 or TOP3 YER120W SCS2 required for inositol metabolism YER122C GLO3 zinc finger protein YER127W LCP5 NGG1P interacting protein YER129W PAK1 DNA polymerase alpha suppressing protein kinase YER130C YER130C similarity to MSN2P and weak similarity to MSN4P YER146W LSM5 Sm-like (Lsm) protein YER148W SPT15 the TATA-binding protein TBP YER151C UBP3 ubiquitin-specific proteinase YER159C BUR6 functional homolog of human NC2alpha YER161C SPT2 multifunctional HMG-like chromatin protein YER164W CHD1 transcriptional regulator YER165W PAB1 mRNA polyadenylate-binding protein YER168C CCA1 tRNA nucleotidyltransferase YER169W RPH1 similarity to human retinoblastoma binding protein 2 YER171W RAD3 DNA helicase/ATPase YER172C BRR2 RNA helicase-related protein YER184C YER184C similarity to multidrug resistance proteins PDR3P and PDR1P YFL001W DEG1 pseudouridine synthase YFL002C SPB4 ATP-dependent RNA helicase of DEAH box family YFL017W-A SMX2 snRNP G protein (the homologue of the human Sm-G) YFL021W GAT1 transcription factor for nitrogen regulation YFL028C CAF16 ATP-binding cassette transporter family member YFL031W HAC1 transcription factor YFL033C RIM15 protein kinase involved in expression of meiotic genes YFL036W RPO41 DNA-directed RNA polymerase, mitochondrial YFL052W YFL052W strong similarity to Mal63p, YPR196w and MAL13P YFR005C SAD1 SnRNP assembly defective YFR029W PTR3 regulator of expression of the PTR2, GAP1 and BAP2 genes YFR034C PHO4 transcription factor YFR037C RSC8 subunit of the RSC complex YGL013C PDR1 transcription factor YGL014W PUF4 similarity to Drosophila pumilio protein and MPT5P protein YGL019W CKB1 casein kinase II, beta subunit YGL025C PGD1 mediator complex subunit YGL035C MIG1 transcriptional repressor YGL043W DST1 TFIIS (transcription elongation factor) YGL044C RNA15 component of pre-mRNA 3'-end processing factor CF I YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL063W PUS2 pseudouridine synthase 2 YGL070C RPB9 DNA-directed RNA polymerase II, 14.2 KD subunit YGL071W RCS1 iron-regulated transcriptional repressor YGL073W HSF1 heat shock transcription factor YGL078C DBP3 putative RNA helicase required for pre-rRNA processing YGL092W NUP145 nuclear pore protein YGL094C PAN2 component of PAB1P-stimulated poly(A) ribonuclease YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL105W ARC1 protein with specific affinity for G4 quadruplex nucleic acids YGL112C TAF60 TFIID and SAGA subunit YGL115W SNF4 nuclear regulatory protein YGL120C PRP43 involved in spliceosome disassembly YGL122C NAB2 nuclear poly(A)-binding protein YGL127C SOH1 allows HPR1 null mutant to grow at 37 deg. YGL130W CEG1 mRNA guanylyltransferase (mRNA capping enzyme, alpha subunit) YGL133W ITC1 subunit of ISW2 chromatin remodelling complex YGL141W HUL5 ubiquitin-protein ligase (E3) YGL150C INO80 similarity to SNF2P and human SNF2alpha YGL151W NUT1 negative transcription regulator from artifical reporters YGL166W CUP2 copper-dependent transcription factor YGL171W ROK1 ATP-dependent RNA helicase YGL172W NUP49 nuclear pore protein YGL173C KEM1 multifunctional nuclease YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL192W IME4 positive transcription factor for IME2 YGL208W SIP2 dominant suppressor of some ts mutations in RPO21 and PRP4 YGL209W MIG2 C2H2 zinc-finger protein YGL221C NIF3 NGG1P-interacting factor 3 YGL237C HAP2 CCAAT-binding factor subunit YGL243W TAD1 tRNA-specific adenosine deaminase 1 YGL244W RTF1 regulates DNA binding properties of TBP YGL251C HFM1 DNA/RNA helicase YGL254W FZF1 sulfite resistance protein YGR005C TFG2 TFIIF subunit (transcription initiation factor), 54 kD YGR006W PRP18 U5 snRNA-associated protein YGR013W SNU71 associated with U1 snRNP, no counterpart in mammalian U1 snRNP YGR030C POP6 required for processing of tRNAs and rRNAs YGR044C RME1 zinc-finger transcription factor YGR047C TFC4 TFIIIC (transcription initiation factor) subunit, 131 kD YGR063C SPT4 transcription elongation protein YGR067C YGR067C weak similarity to transcription factors YGR074W SMD1 snRNA-associated protein YGR075C PRP38 pre-mRNA splicing factor YGR091W PRP31 pre-mRNA splicing protein YGR092W DBF2 ser/thr protein kinase related to DBF20P YGR095C RRP46 involved in rRNA processing YGR097W ASK10 involved in SKN7P-dependent transcription YGR100W MDR1 MAC1P interacting protein YGR104C SRB5 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YGR116W SPT6 transcription elongation protein YGR129W SYF2 synthetic lethal with CDC40 YGR158C MTR3 involved in mRNA transport YGR159C NSR1 nuclear localization sequence binding protein YGR186W TFG1 TFIIF subunit (transcription initiation factor), 105 kD YGR195W SKI6 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YGR200C ELP2 29 kDa subunit of elongator and elongating RNA polymerase II holoenzyme YGR204W ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YGR218W CRM1 nuclear export factor, exportin YGR222W PET54 splicing protein and translational activator, mitochondrial YGR246C BRF1 TFIIIB subunit, 70 kD YGR248W SOL4 strong similarity to SOL3P YGR249W MGA1 similarity to heat shock transcription factors YGR252W GCN5 histone acetyltransferase YGR274C TAF145 TFIID subunit (TBP-associated factor), 145 kD YGR288W MAL13 maltose pathway regulatory protein YHL009C YAP3 transcription factor, of a fungal-specific family of bzip proteins YHL020C OPI1 negative regulator of phospholipid biosynthesis pathway YHL025W SNF6 global transcription activator YHL027W RIM101 meiotic regulatory protein YHL034C SBP1 single-strand nucleic acid binding protein YHL038C CBP2 apo-cytochrome b pre-mRNA processing protein 2 YHR006W STP2 involved in pre-tRNA splicing YHR015W MIP6 similarity to PES4 a PAB-like protein YHR041C SRB2 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YHR056C RSC30 strong similarity to YHR054c YHR058C MED6 RNA polymerase II transcriptional regulation mediator YHR062C RPP1 required for processing of tRNA and 35S rRNA YHR065C RRP3 required for maturation of the 35S primary transcript YHR069C RRP4 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YHR072W-A NOP10 nucleolar rRNA processing protein YHR084W STE12 transcriptional activator YHR086W NAM8 meiotic recombination protein YHR089C GAR1 nucleolar rRNA processing protein YHR099W TRA1 component of the Ada-Spt transcriptional regulatory complex YHR118C ORC6 origin recognition complex, 50 KD subunit YHR143W-A RPC10 DNA-directed RNA polymerases I, II, III 7.7 KD subunit YHR148W IMP3 component of the U3 small nucleolar ribonucleoprotein YHR154W ESC4 Establishes Silent Chromatin YHR163W SOL3 possible 6-phosphogluconolactonase YHR165C PRP8 U5 snRNP protein, pre-mRNA splicing factor YHR169W DBP8 strong similarity to DRS1P and other probable ATP-dependent RNA helicases YHR170W NMD3 nonsense-mediated mRNA decay protein YHR178W STB5 SIN3 binding protein YHR193C EGD2 alpha subunit of the nascent polypeptide-associated complex YHR206W SKN7 transcription factor with similarity to HSF1P YHR211W FLO5 member of the FLO1P family of flocculation proteins YIL010W DOT5 involved in derepression of telomeric silencing YIL021W RPB3 DNA-directed RNA-polymerase II, 45 kDa YIL030C SSM4 involved in mRNA turnover YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL035C CKA1 casein kinase II, catalytic alpha chain YIL036W CST6 ATF/CREB activator YIL038C NOT3 general negative regulator of transcription, subunit 3 YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL061C SNP1 U1 small nuclear ribonucleoprotein YIL075C RPN2 26S proteasome regulatory subunit YIL084C SDS3 transcriptional regulator YIL101C XBP1 stress-induced transcriptional repressor YIL105C YIL105C weak similarity to probable transcription factor ASK10P YIL106W MOB1 required for completion of mitosis and maintenance of ploidy YIL126W STH1 subunit of the RSC complex YIL128W MET18 involved in NER repair and RNA polymerase II transcription YIL129C TAO3 Transcriptional Activator of OCH1 YIL130W YIL130W similarity to PUT3P and to hypothetical protein YJL206c YIL131C FKH1 forkhead protein, involved in transcriptional silencing, cell morphology and cell cycle YIL143C SSL2 DNA helicase YIR001C SGN1 similarity to D.melanogaster RNA binding protein YIR005W IST3 similarity to RNA-binding proteins YIR009W MSL1 U2 snRNA-associated protein with similarity to U2B YIR011C STS1 required for transport of RNA15P from the cytoplasm to the nucleus YIR015W RPR2 RNase P subunit YIR017C MET28 transcriptional activator of sulfur amino acid metabolism YIR018W YAP5 involved in transcription activation YIR021W MRS1 involved in mitochondrial RNA splicing of COB mRNA YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YJL006C CTK2 carboxy-terminal domain (CTD) kinase, beta subunit YJL025W RRN7 polymerase I specific transcription initiation factor YJL033W HCA4 can suppress the U14 snoRNA rRNA processing function YJL035C TAD2 tRNA-specific adenosine deaminase 2 YJL041W NSP1 nuclear pore protein YJL050W MTR4 involved in nucleocytoplasmic transport of mRNA YJL056C ZAP1 metalloregulatory protein involved in zinc-responsive transcriptional regulation YJL061W NUP82 nuclear pore protein YJL076W NET1 required for rDNA silencing and nucleolar integrity YJL087C TRL1 tRNA ligase YJL089W SIP4 interacts with SNF1 protein kinase YJL103C YJL103C similarity to YBR239c YJL110C GZF3 transcriptional repressor YJL115W ASF1 anti-silencing protein YJL124C LSM1 Sm-like (Lsm) protein YJL127C SPT10 transcription regulatory protein YJL133W MRS3 RNA splicing protein and member of the mitochondrial carrier family (MCF) YJL140W RPB4 DNA-directed RNA polymerase II, 32 kDa subunit YJL148W RPA34 nonessential component of RNA-polI YJL164C TPK1 cAMP-dependent protein kinase 1, catalytic chain YJL168C SET2 enhancer of zeste-like YJL176C SWI3 transcription regulatory protein YJL203W PRP21 pre-mRNA splicing factor YJL206C YJL206C similarity to YIL130p and PUT3P YJL209W CBP1 apo-cytochrome b pre-mRNA processing protein YJR002W MPP10 component of the U3 small nucleolar ribonucleoprotein YJR017C ESS1 processing/termination factor 1 YJR022W LSM8 splicing factor YJR032W CPR7 member of the cyclophilin family YJR036C HUL4 hect domain E3 ubiquitin-protein ligase YJR042W NUP85 nuclear pore protein YJR050W ISY1 pre-mRNA splicing factor YJR060W CBF1 kinetochore protein YJR063W RPA12 DNA-directed RNA polymerase I, 13.7 KD subunit YJR093C FIP1 component of pre-mRNA polyadenylation factor PF I YJR094C IME1 transcription factor required for sporulation YJR119C YJR119C similarity to human retinoblastoma binding protein 2 YJR122W CAF17 CCR4 associated factor YJR127C ZMS1 transcription factor with similarity to regulatory protein ARD1P YJR140C HIR3 involved in cell cycle regulation of histone transcription YJR147W HMS2 High-copy MEP2 Suppressor YKL005C YKL005C weak similarity to YKR029c and D.melanogaster transcription elongation factor DmS-II YKL009W MRT4 mRNA turnover 4 YKL012W PRP40 splicing factor YKL015W PUT3 positive activator of the proline utilisation pathway YKL025C PAN3 component of the PAB1P-dependent poly(A) ribonuclease YKL028W TFA1 TFIIE subunit (transcription initiation factor), 66 kD YKL032C IXR1 intrastrand crosslink recognition protein and transcription factor YKL038W RGT1 regulator of glucose-induced genes YKL043W PHD1 transcription factor YKL057C NUP120 nuclear pore protein YKL058W TOA2 TFIIA subunit (transcription initiation factor), 13.5 kD YKL062W MSN4 transcriptional activator YKL068W NUP100 nuclear pore protein YKL070W YKL070W similarity to B.subtilis transcriptional regulatory protein YKL072W STB6 SIN3 binding protein YKL074C MUD2 pre-mRNA splicing factor YKL078W DHR2 RNA helicase, involved in ribosomal RNA maturation YKL093W MBR1 required for optimal growth on glycerol YKL109W HAP4 CCAAT-binding factor subunit YKL112W ABF1 ARS-binding factor YKL125W RRN3 RNA polymerase I specific transcription factor YKL139W CTK1 carboxy-terminal domain (CTD) kinase, alpha subunit YKL144C RPC25 DNA-direcred RNA polymerase III, 25 KD subunit YKL159C RCN1 inhibitor of calcineurin YKL166C TPK3 cAMP-dependent protein kinase 3, catalytic chain YKL172W EBP2 required for pre-rRNA processing and ribosomal subunit assembly YKL185W ASH1 negative regulator of HO transcription YKL186C MTR2 mRNA transport protein YKL190W CNB1 calcineurin B, regulatory subunit YKL205W LOS1 pre-tRNA splicing protein YKL208W CBT1 apo-cytochrome b pre-mRNA processing protein YKL222C YKL222C weak similarity to transcription factors, similarity to finger proteins YOR162c, YOR172w and YLR266c YKR002W PAP1 poly(A) polymerase YKR019C IRS4 Increased rDNA silencing YKR024C DBP7 RNA helicase required for 60S ribosomal subunit assembly YKR025W RPC37 Pol III transcription YKR034W DAL80 transcriptional repressor for allantoin and GABA catabolic genes YKR036C CAF4 CCR4 associated factor YKR052C MRS4 RNA splicing protein and member of the mitochondrial carrier family (MCF) YKR056W RNC1 tRNA(m5U54)methyltransferase YKR062W TFA2 TFIIE subunit (transcription initiation factor), 43 KD YKR064W YKR064W weak similarity to transcription factors YKR072C SIS2 involved in cell cycle-specific gene expression YKR082W NUP133 nuclear pore protein YKR086W PRP16 RNA-dependent ATPase YKR092C SRP40 suppressor of mutant AC40 of RNA polymerase I and III YKR099W BAS1 transcription factor YKR101W SIR1 silencing regulatory protein YLL004W ORC3 origin recognition complex, 62 kDa subunit YLL008W DRS1 RNA helicase of the DEAD box family YLL011W SOF1 involved in 18S pre-rRNA production YLL036C PRP19 non-snRNP sliceosome component required for DNA repair YLL054C YLL054C similarity to transcription factor PIP2P YLR005W SSL1 TFIIH subunit (transcription initiation factor), factor B YLR013W GAT3 weak similarity to nitrogen regulatory proteins YLR014C PPR1 transcription factor regulating pyrimidine pathway YLR039C RIC1 involved in transcription of ribosomal proteins and ribosomal RNA YLR055C SPT8 transcriptional adaptor or co-activator YLR059C REX2 putative 3'-5' exonuclease YLR067C PET309 required for stability and translation of COX1 mRNA YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR098C CHA4 transcription factor YLR105C SEN2 tRNA splicing endonuclease beta subunit YLR115W CFT2 cleavage and polyadenylation specificity factor, part of CF II YLR116W MSL5 branch point bridging protein YLR117C CLF1 strong similarity to Drosophila putative cell cycle control protein crn YLR119W SRN2 suppressor of RNA1-1 mutation YLR131C ACE2 metallothionein expression activator YLR136C TIS11 tRNA-specific adenosine deaminase 3 YLR139C SLS1 suppresses lethality of SSM4 deletion YLR141W RRN5 RNA polymerase I specific transcription initiation factor YLR147C SMD3 spliceosomal snRNA-associated Sm core protein required for pre-mRNA splicing YLR175W CBF5 putative rRNA pseuduridine synthase YLR176C RFX1 repressor of DNA damage-inducible genes YLR182W SWI6 transcription factor YLR192C HCR1 component of translation initiation factor eIF3, has similarity to human eIF3 p35 subunit YLR197W SIK1 involved in pre-rRNA processing YLR216C CPR6 member of the cyclophilin family YLR223C IFH1 pre-rRNA processing machinery control protein YLR226W BUR2 divergent CDK-cyclin complex YLR228C ECM22 strong similarity to YDR213w, weak similarity to LYS14P YLR256W HAP1 transcription factor YLR266C YLR266C weak similarity to transcription factors YLR275W SMD2 U1 snRNP protein of the Sm class YLR277C YSH1 component of pre-mRNA polyadenylation factor PF I YLR278C YLR278C weak similarity to regulatory proteins YLR293C GSP1 GTP-binding protein of the ras superfamily YLR298C YHC1 associated with the U1 snRNP complex YLR316C TAD3 subunit of tRNA-specific adenosine-34 deaminase YLR321C SFH1 subunit of the RSC complex YLR375W STP3 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YLR382C NAM2 leucine--tRNA ligase precursor, mitochondrial YLR399C BDF1 sporulation protein YLR418C CDC73 DNA-directed RNA polymerase II accessory protein YLR430W SEN1 positive effector of tRNA-splicing endonuclease YLR433C CNA1 calcineurin B, catalytic subunit YLR438C-A LSM3 Sm-like (Lsm) protein YLR442C SIR3 silencing regulatory and DNA-repair protein YLR451W LEU3 transcription factor YML007W YAP1 transcriptional activator involved in oxidative stress response YML010W SPT5 transcription elongation protein YML015C TAF40 TFIID subunit (TBP-associated factor), 40KD YML017W PSP2 suppressor of DNA polymerase alpha mutation YML027W YOX1 homoeodomain protein YML043C RRN11 RNA polymerase I specific transcription initiation factor YML046W PRP39 pre-mRNA splicing factor YML049C RSE1 involved in RNA splicing and ER to Golgi transport YML051W GAL80 negative regulator for expression of galactose-induced genes YML057W CMP2 calcineurin B, catalytic subunit YML065W ORC1 origin recognition complex, 104 KD subunit YML069W POB3 protein that binds to DNA polymerase I (PolI) YML076C YML076C weak similarity to transcription factor YML081W YML081W strong similarity to ZMS1 protein YML091C RPM2 ribonuclease P precursor, mitochondrial YML098W TAF19 TFIID subunit (TBP-associated factor), 19 kD YML099C ARG81 transcription factor involved in arginine metabolism YML112W CTK3 carboxy-terminal domain (CTD) kinase, gamma subunit YML114C TAF65 TBP Associated Factor 65 KDa YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR019W STB4 weak similarity to YIL130w, PUT3P and other transcription factors YMR021C MAC1 metal binding activator YMR023C MSS1 mitochondrial GTPase involved in expression of COX1 YMR037C MSN2 stress responsive regulatory protein YMR039C SUB1 transcriptional coactivator YMR042W ARG80 transcription factor involved in arginine metabolism YMR043W MCM1 transcription factor of the MADS box family YMR047C NUP116 nuclear pore protein YMR053C STB2 SIN3P binding protein YMR059W SEN15 tRNA splicing endonuclease delta subunit YMR061W RNA14 component of pre-mRNA 3'-end processing factor CF I YMR064W AEP1 nuclear control of ATPase messenger RNA expression protein YMR070W MOT3 high-copy suppressor of MOT1-SPT3 synthetic lethality YMR112C MED11 mediator complex subunit YMR125W STO1 large subunit of the nuclear cap-binding protein complex CBC YMR127C SAS2 involved in silencing at HMR YMR131C RRB1 involved in the regulation of ribosome biosynthesis YMR139W RIM11 ser/thr protein kinase YMR164C MSS11 activator of STA1, STA2, and STA3 YMR179W SPT21 required for normal transcription at a number of loci YMR180C CTL1 RNA 5'-triphosphatase with manganese- or cobalt-dependent NTPase activities YMR182C RGM1 transcriptional repressor protein YMR219W ESC1 Establishes Silent Chromatin YMR227C TAF67 TFIID subunit (TBP-associated factor), 67 kD YMR228W MTF1 RNA polymerase specific factor, mitochondrial YMR229C RRP5 processing of pre-ribosomal RNA YMR235C RNA1 GTPase activating protein YMR236W TAF17 TFIID and SAGA subunit YMR239C RNT1 double-stranded ribonuclease YMR240C CUS1 U2 snRNP protein YMR263W SAP30 subunit of the histone deacetylase B complex YMR268C PRP24 pre-mRNA splicing factor YMR270C RRN9 RNA polymerase I specific transcription initiation factor YMR277W FCP1 TFIIF interacting component of CTD phosphatase YMR280C CAT8 transcription factor involved in gluconeogenesis YMR283C RIT1 initiator tRNA phosphoribosyl-transferase YMR287C MSU1 3'-5' exonuclease for RNA 3' ss-tail, mitochondrial YMR288W HSH155 component of a multiprotein splicing factor YMR302C PRP12 involved in early maturation of pre-rRNA YMR312W ELP6 subunit of RNA polymerase II elongator complex YNL004W HRB1 strong similarity to GBP2P YNL012W SPO1 transcriptional regulator involved in sporulation YNL016W PUB1 major polyadenylated RNA-binding protein of nucleus and cytoplasm YNL021W HDA1 histone deacetylase A YNL025C SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YNL027W CRZ1 calcineurin responsive zinc-finger YNL030W HHF2 histone H4 YNL031C HHT2 histone H3 YNL037C IDH1 isocitrate dehydrogenase (NAD+) subunit 1, mitochondrial YNL039W BDP1 TFIIIB subunit, 90 kD YNL061W NOP2 nucleolar protein YNL062C GCD10 translation initiation factor eIF3 RNA-binding subunit YNL068C FKH2 homology to D.melanogaster forkhead protein YNL075W IMP4 component of the U3 small nucleolar ribonucleoprotein YNL076W MKS1 pleiotropic regulatory factor YNL097C PHO23 involved in transcriptional regulation of PHO5 YNL103W MET4 transcriptional activator of sulfur metabolism YNL107W YAF9 similarity to human AF-9 protein YNL112W DBP2 ATP-dependent RNA helicase of DEAD box family YNL113W RPC19 DNA-directed RNA polymerase I,III 16 KD subunit YNL139C RLR1 regulatory protein YNL147W LSM7 Sm-like (Lsm) protein YNL151C RPC31 DNA-directed RNA polymerase III, 31 KD subunit YNL167C SKO1 cre-binding bzip protein YNL175C NOP13 similarity to S.pombe Rnp24p, NSR1P and human splicing factor YNL186W UBP10 derepression of telomeric silencing YNL199C GCR2 glycolytic genes transcriptional activator YNL204C SPS18 sporulation-specific zinc-finger protein YNL210W MER1 meiotic recombination protein YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL221C POP1 protein component of ribonuclease P and ribonuclease MRP YNL222W SSU72 suppressor of cs mutant of SUA7 YNL236W SIN4 global regulator protein YNL248C RPA49 DNA-directed RNA polymerase A (I) chain, 46 kDa YNL251C NRD1 involved in regulation of nuclear pre-mRNA abundance YNL255C GIS2 strong similarity to nucleic acid-binding proteins, similarity to Tetrahymena thermophila cnjB protein YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL282W POP3 involved in processsing of tRNAs and rRNAs YNL286W CUS2 cold sensitive U2 snRNA Suppressor YNL292W PUS4 pseudouridine synthase YNL309W STB1 SIN3P binding protein YNL314W DAL82 transcriptional activator for allantoin catabolic genes YNL317W PFS2 polyadenylation factor I subunit 2 required for mRNA 3'-end processing, bridges two mRNA 3'-end processing factors YNL330C RPD3 histone deacetylase B YNR003C RPC34 DNA-directed RNA polymerase III, 34 KD subunit YNR010W CSE2 subunit of RNA polymerase II mediator complex YNR011C PRP2 RNA-dependent ATPase of DEAH box family YNR023W SNF12 component of SWI/SNF global transcription activator complex YNR034W SOL1 multicopy suppressor of LOS1-1 YNR038W DBP6 RNA helicase required for 60S ribosomal subunit assembly YNR052C POP2 required for glucose derepression YNR063W YNR063W weak similarity to CYC1/CYP3 transcription activator YOL001W PHO80 cyclin YOL004W SIN3 transcription regulatory protein YOL005C RPB11 DNA-directed RNA polymerase II subunit, 13.6 kD YOL006C TOP1 DNA topoisomerase I YOL010W RCL1 similarity to human RNA 3'-terminal phosphate cyclase YOL021C DIS3 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YOL028C YAP7 involved in transcription activation YOL042W NGL1 similarity to CCR4 protein YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL055C THI20 hydroxymethylpyrimidine phosphate (HMP-P) kinase YOL067C RTG1 basic helix-loop-helix transcription factor that regulates CIT2 gene expression YOL068C HST1 silencing protein YOL089C HAL9 transcriptional activator of ENA1 YOL102C TPT1 tRNA 2'-phosphotransferase YOL108C INO4 basic helix-loop-helix transcription factor YOL116W MSN1 transcriptional activator YOL123W HRP1 CF Ib (RNA3' Cleavage factor Ib) YOL133W HRT1 similarity to Lotus RING-finger protein YOL135C MED7 member of RNA Polymerase II transcriptional regulation mediator complex YOL148C SPT20 member of the TBP class of SPT proteins that alter transcription site selection YOL149W DCP1 mRNA decapping enzyme YOR025W HST3 silencing protein YOR028C CIN5 transcriptional activator YOR038C HIR2 histone transcription regulator YOR039W CKB2 casein kinase II beta' chain YOR047C STD1 dosage-dependent modulator of glucose repression YOR048C RAT1 5'-3' exoribonuclease YOR061W CKA2 casein kinase II alpha' chain YOR110W TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa YOR113W AZF1 asparagine-rich zinc finger protein YOR116C RPO31 DNA-directed RNA polymerase III, 160 KD subunit YOR136W IDH2 isocitrate dehydrogenase (NAD+) subunit 2, mitochondrial YOR140W SFL1 transcription factor YOR148C SPP2 involved in pre-mRNA processing YOR151C RPB2 DNA-directed RNA polymerase II, 140 kDa chain YOR159C SME1 spliceosomal snRNA-associated Sm core protein required for mRNA splicing, also likely associated with telomerase TLC1 RNA YOR160W MTR10 involved in nuclear protein import YOR162C YRR1 transcription factor YOR174W MED4 transcription regulation mediator YOR179C YOR179C similarity to BRR5 protein YOR185C GSP2 GTP-binding protein of the RAS superfamily YOR194C TOA1 TFIIA subunit (transcription initiation factor), 32 kD YOR201C PET56 rRNA (guanosine-2'-O-)-methyltransferase YOR204W DED1 ATP-dependent RNA helicase YOR207C RET1 DNA-directed RNA polymerase III, 130 KD subunit YOR210W RPB10 DNA-directed polymerase I, II, III 8.3 subunit YOR213C SAS5 subunit of the RSC complex YOR224C RPB8 DNA-directed RNA polymerase I, II, III 16 KD subunit YOR229W WTM2 transcriptional modulator YOR230W WTM1 transcriptional modulator YOR250C CLP1 cleavage/polyadenylation factor IA subunit YOR259C RPT4 26S proteasome regulatory subunit YOR274W MOD5 tRNA isopentenyltransferase YOR290C SNF2 component of SWI/SNF global transcription activator complex YOR294W RRS1 regulator of ribosome synthesis YOR295W UAF30 subunit of RNA polymerase I transcription factor YOR298C-A MBF1 multiprotein bridging factor mediates GCN4-dependent transcriptional activation YOR304W ISW2 strong similarity to Drosophila ISW1 and human SNF2P homolog YOR308C SNU66 component of U4/U6.U5 snRNP YOR310C NOP58 required for pre-18S rRNA processing YOR319W HSH49 essential yeast splicing factor YOR334W MRS2 RNA splicing protein and member of the mitochondrial carrier family (MCF) YOR337W TEA1 TY1 enhancer activator YOR340C RPA43 DNA-directed RNA polymerase I, 36 KD subunit YOR341W RPA190 DNA-directed RNA polymerase I, 190 KD alpha subunit YOR344C TYE7 basic helix-loop-helix transcription factor YOR358W HAP5 CCAAT-binding factor subunit YOR363C PIP2 peroxisome proliferating transcription factor YPL007C TFC8 RNA Polymerase III transcription initiation factor TFIIIC (tau), 60 kDa subunit YPL011C TAF47 component of the TBP-associated protein complex YPL015C HST2 similarity to HST1P and SIR2P YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL031C PHO85 cyclin-dependent protein kinase YPL037C EGD1 GAL4 DNA-binding enhancer protein YPL038W MET31 transcriptional regulator of sulfur amino acid metabolism YPL042C SSN3 cyclin-dependent CTD kinase YPL043W NOP4 nucleolar protein YPL046C ELC1 Elongin C transcription elongation factor YPL060W LPE10 strong similarity to MRS2P YPL075W GCR1 transcriptional activator YPL082C MOT1 transcriptional accessory protein YPL083C SEN54 tRNA splicing endonuclease alpha subunit YPL089C RLM1 transcription factor of the MADS box family YPL101W ELP4 RNA polymerase II Elongator protein subunit YPL119C DBP1 ATP-dependent RNA helicase YPL122C TFB2 TFIIH subunit (transcription/repair factor) YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL133C YPL133C weak similarity to transcription factors YPL139C UME1 negative regulator of meiosis YPL169C MEX67 factor for nuclear mRNA export YPL177C CUP9 involved in copper homeostasis repression of protein import YPL178W CBC2 small subunit of the nuclear cap-binding protein complex CBC YPL190C NAB3 polyadenylated RNA-binding protein YPL203W TPK2 cAMP-dependent protein kinase 2, catalytic chain YPL211W NIP7 required for efficient 60S ribosome subunit biogenesis YPL212C PUS1 pseudouridine synthase 1 YPL213W LEA1 U2 A' snRNP protein YPL217C BMS1 GTP-binding protein, required for distinct steps of 40S ribosome biogenesis YPL228W CET1 RNA 5'-triphosphatase (mRNA capping enzyme, beta subunit) YPL230W USV1 similarity to RGM1P, weak similarity to transcription factors YPL248C GAL4 transcription factor YPL254W HFI1 transcriptional coactivator YPL266W DIM1 rRNA (adenine-N6,N6-)-dimethyltransferase YPR008W HAA1 similarity to transcription factor YPR010C RPA135 DNA-directed RNA polymerase I, 135 KD subunit YPR013C YPR013C similarity to transcription factors YPR015C YPR015C similarity to transcription factors YPR025C CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPR031W YPR031W similarity to human zinc-finger protein BR140 YPR056W TFB4 component of RNA polymerase transcription initiation TFIIH factor YPR057W BRR1 involved in snRNP biogenesis YPR065W ROX1 heme-dependent transcriptional repressor of hypoxic genes YPR068C HOS1 similarity to human histone deacetylase HD1 YPR070W MED1 component of RNA polymerase II holoenzyme and mediator subcomplex YPR072W NOT5 component of the NOT protein complex YPR086W SUA7 TFIIB subunit (transcription initiation factor), factor E YPR101W SNT309 splicing factor YPR104C FHL1 transcriptional activator of the forkhead/hnf3 family YPR107C YTH1 protein of the 3' processing complex YPR110C RPC40 DNA-directed RNA polymerase I, III 40 KD subunit YPR115W YPR115W similarity to probable transcription factor ASK10P, and to YNL047c and YIL105c YPR125W MRS7 suppressor of MRS2-1 mutation YPR134W MSS18 splicing protein YPR137W RRP9 protein associated with the U3 small nucleolar RNA, required for pre-ribosomal RNA processing YPR162C ORC4 origin recognition complex, 56 KD subunit YPR168W NUT2 negative transcription regulator from artifical reporters YPR178W PRP4 U4/U6 snRNP 52 KD protein YPR182W SMX3 snRNA-associated protein of the SM family YPR186C PZF1 TFIIIA (transcription initiation factor) YPR187W RPO26 DNA-directed RNA polymerase I, II, III 18 KD subunit YPR190C RPC82 DNA-directed RNA polymerase III, 82 KD subunit YPR196W YPR196W strong similarity to regulatory protein Mal63p YPR199C ARR1 involved in resistance to arsenic compounds Q0050 AI1 COX1 intron 1 protein Q0055 AI2 COX1 intron 2 protein Q0060 AI3 DNA endonuclease Q0065 AI4 DNA endonuclease Q0070 AI5_ALPHA DNA endonuclease AI5_ALPHA Q0110 BI2 mRNA maturase BI2 Q0115 BI3 mRNA maturase BI3 Q0120 BI4 mRNA maturase BI4 Q0160 SCEI DNA endonuclease in 21S rRNA intron Q0255 Q0255 similarity to Podospora cytb intron 1a and coII intron protein 2 rRNA transcription (109 ORFs) 04.01 109 YAL001C TFC3 TFIIIC (transcription initiation factor) subunit, 138 kD YAL033W POP5 required for processing of tRNAs and rRNAs YBL014C RRN6 RNA polymerase I specific transcription initiation factor YBL018C POP8 required for processing of tRNAs and rRNAs YBL025W RRN10 RNA polymerase I-specific transcription initiation factor YBR049C REB1 transcription factor YBR123C TFC1 TFIIIC (transcription initiation factor) subunit, 95 kD YBR142W MAK5 ATP-dependent RNA helicase YBR154C RPB5 DNA-directed RNA polymerase I, II, III 25 KD subunit YBR167C POP7 nuclear RNase P subunit YBR257W POP4 involved in processing of tRNAs and rRNAs YCL031C RRP7 involved in pre-rRNA processing and ribosome assembly YCR018C SRD1 nucleolar protein YCR035C RRP43 rRNA processing protein YDL014W NOP1 fibrillarin YDL111C RRP42 rRNA processing protein YDL150W RPC53 DNA-directed RNA polymerase III, 47 KD subunit YDL208W NHP2 nucleolar rRNA processing protein YDR021W FAL1 involved in maturation of 18S rRNA YDR083W RRP8 protein involved in cleavage at site A2 in pre-rRNA in the pathway of ribosomal RNA processing YDR087C RRP1 involved in processing rRNA precursor species to mature rRNAs YDR156W RPA14 DNA-directed RNA polymerase I, A14 subunit YDR280W RRP45 rRNA processing protein YDR362C TFC6 TFIIIC (transcription initiation factor) subunit, 91 kD YDR432W NPL3 nucleolar protein YDR478W SNM1 RNA binding protein of RNase MRP YER127W LCP5 NGG1P interacting protein YER148W SPT15 the TATA-binding protein TBP YFL002C SPB4 ATP-dependent RNA helicase of DEAH box family YGL078C DBP3 putative RNA helicase required for pre-rRNA processing YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL171W ROK1 ATP-dependent RNA helicase YGL173C KEM1 multifunctional nuclease YGR030C POP6 required for processing of tRNAs and rRNAs YGR047C TFC4 TFIIIC (transcription initiation factor) subunit, 131 kD YGR095C RRP46 involved in rRNA processing YGR158C MTR3 involved in mRNA transport YGR159C NSR1 nuclear localization sequence binding protein YGR195W SKI6 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YGR246C BRF1 TFIIIB subunit, 70 kD YHL034C SBP1 single-strand nucleic acid binding protein YHR062C RPP1 required for processing of tRNA and 35S rRNA YHR065C RRP3 required for maturation of the 35S primary transcript YHR069C RRP4 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YHR072W-A NOP10 nucleolar rRNA processing protein YHR089C GAR1 nucleolar rRNA processing protein YHR143W-A RPC10 DNA-directed RNA polymerases I, II, III 7.7 KD subunit YHR148W IMP3 component of the U3 small nucleolar ribonucleoprotein YJL025W RRN7 polymerase I specific transcription initiation factor YJL033W HCA4 can suppress the U14 snoRNA rRNA processing function YJL076W NET1 required for rDNA silencing and nucleolar integrity YJL148W RPA34 nonessential component of RNA-polI YJR002W MPP10 component of the U3 small nucleolar ribonucleoprotein YJR063W RPA12 DNA-directed RNA polymerase I, 13.7 KD subunit YKL125W RRN3 RNA polymerase I specific transcription factor YKL144C RPC25 DNA-direcred RNA polymerase III, 25 KD subunit YKL172W EBP2 required for pre-rRNA processing and ribosomal subunit assembly YKR019C IRS4 Increased rDNA silencing YKR024C DBP7 RNA helicase required for 60S ribosomal subunit assembly YLL008W DRS1 RNA helicase of the DEAD box family YLL011W SOF1 involved in 18S pre-rRNA production YLR039C RIC1 involved in transcription of ribosomal proteins and ribosomal RNA YLR059C REX2 putative 3'-5' exonuclease YLR141W RRN5 RNA polymerase I specific transcription initiation factor YLR175W CBF5 putative rRNA pseuduridine synthase YLR197W SIK1 involved in pre-rRNA processing YLR223C IFH1 pre-rRNA processing machinery control protein YML043C RRN11 RNA polymerase I specific transcription initiation factor YMR131C RRB1 involved in the regulation of ribosome biosynthesis YMR229C RRP5 processing of pre-ribosomal RNA YMR235C RNA1 GTPase activating protein YMR239C RNT1 double-stranded ribonuclease YMR270C RRN9 RNA polymerase I specific transcription initiation factor YMR302C PRP12 involved in early maturation of pre-rRNA YNL039W BDP1 TFIIIB subunit, 90 kD YNL061W NOP2 nucleolar protein YNL075W IMP4 component of the U3 small nucleolar ribonucleoprotein YNL112W DBP2 ATP-dependent RNA helicase of DEAD box family YNL113W RPC19 DNA-directed RNA polymerase I,III 16 KD subunit YNL151C RPC31 DNA-directed RNA polymerase III, 31 KD subunit YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL221C POP1 protein component of ribonuclease P and ribonuclease MRP YNL248C RPA49 DNA-directed RNA polymerase A (I) chain, 46 kDa YNL282W POP3 involved in processsing of tRNAs and rRNAs YNR003C RPC34 DNA-directed RNA polymerase III, 34 KD subunit YNR038W DBP6 RNA helicase required for 60S ribosomal subunit assembly YOL021C DIS3 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YOR048C RAT1 5'-3' exoribonuclease YOR110W TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa YOR116C RPO31 DNA-directed RNA polymerase III, 160 KD subunit YOR201C PET56 rRNA (guanosine-2'-O-)-methyltransferase YOR207C RET1 DNA-directed RNA polymerase III, 130 KD subunit YOR210W RPB10 DNA-directed polymerase I, II, III 8.3 subunit YOR224C RPB8 DNA-directed RNA polymerase I, II, III 16 KD subunit YOR294W RRS1 regulator of ribosome synthesis YOR295W UAF30 subunit of RNA polymerase I transcription factor YOR310C NOP58 required for pre-18S rRNA processing YOR340C RPA43 DNA-directed RNA polymerase I, 36 KD subunit YOR341W RPA190 DNA-directed RNA polymerase I, 190 KD alpha subunit YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL043W NOP4 nucleolar protein YPL211W NIP7 required for efficient 60S ribosome subunit biogenesis YPL217C BMS1 GTP-binding protein, required for distinct steps of 40S ribosome biogenesis YPL266W DIM1 rRNA (adenine-N6,N6-)-dimethyltransferase YPR010C RPA135 DNA-directed RNA polymerase I, 135 KD subunit YPR110C RPC40 DNA-directed RNA polymerase I, III 40 KD subunit YPR186C PZF1 TFIIIA (transcription initiation factor) YPR187W RPO26 DNA-directed RNA polymerase I, II, III 18 KD subunit YPR190C RPC82 DNA-directed RNA polymerase III, 82 KD subunit rRNA synthesis (39 ORFs) 04.01.01 39 YAL001C TFC3 TFIIIC (transcription initiation factor) subunit, 138 kD YBL014C RRN6 RNA polymerase I specific transcription initiation factor YBL025W RRN10 RNA polymerase I-specific transcription initiation factor YBR049C REB1 transcription factor YBR123C TFC1 TFIIIC (transcription initiation factor) subunit, 95 kD YBR154C RPB5 DNA-directed RNA polymerase I, II, III 25 KD subunit YDL150W RPC53 DNA-directed RNA polymerase III, 47 KD subunit YDR156W RPA14 DNA-directed RNA polymerase I, A14 subunit YDR362C TFC6 TFIIIC (transcription initiation factor) subunit, 91 kD YER148W SPT15 the TATA-binding protein TBP YGR047C TFC4 TFIIIC (transcription initiation factor) subunit, 131 kD YGR246C BRF1 TFIIIB subunit, 70 kD YHR143W-A RPC10 DNA-directed RNA polymerases I, II, III 7.7 KD subunit YJL025W RRN7 polymerase I specific transcription initiation factor YJL148W RPA34 nonessential component of RNA-polI YJR063W RPA12 DNA-directed RNA polymerase I, 13.7 KD subunit YKL125W RRN3 RNA polymerase I specific transcription factor YKL144C RPC25 DNA-direcred RNA polymerase III, 25 KD subunit YLR039C RIC1 involved in transcription of ribosomal proteins and ribosomal RNA YLR141W RRN5 RNA polymerase I specific transcription initiation factor YML043C RRN11 RNA polymerase I specific transcription initiation factor YMR270C RRN9 RNA polymerase I specific transcription initiation factor YNL039W BDP1 TFIIIB subunit, 90 kD YNL113W RPC19 DNA-directed RNA polymerase I,III 16 KD subunit YNL151C RPC31 DNA-directed RNA polymerase III, 31 KD subunit YNL248C RPA49 DNA-directed RNA polymerase A (I) chain, 46 kDa YNR003C RPC34 DNA-directed RNA polymerase III, 34 KD subunit YOR110W TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa YOR116C RPO31 DNA-directed RNA polymerase III, 160 KD subunit YOR207C RET1 DNA-directed RNA polymerase III, 130 KD subunit YOR210W RPB10 DNA-directed polymerase I, II, III 8.3 subunit YOR224C RPB8 DNA-directed RNA polymerase I, II, III 16 KD subunit YOR340C RPA43 DNA-directed RNA polymerase I, 36 KD subunit YOR341W RPA190 DNA-directed RNA polymerase I, 190 KD alpha subunit YPR010C RPA135 DNA-directed RNA polymerase I, 135 KD subunit YPR110C RPC40 DNA-directed RNA polymerase I, III 40 KD subunit YPR186C PZF1 TFIIIA (transcription initiation factor) YPR187W RPO26 DNA-directed RNA polymerase I, II, III 18 KD subunit YPR190C RPC82 DNA-directed RNA polymerase III, 82 KD subunit rRNA processing (63 ORFs) 04.01.04 63 YAL033W POP5 required for processing of tRNAs and rRNAs YBL018C POP8 required for processing of tRNAs and rRNAs YBR142W MAK5 ATP-dependent RNA helicase YBR167C POP7 nuclear RNase P subunit YBR257W POP4 involved in processing of tRNAs and rRNAs YCL031C RRP7 involved in pre-rRNA processing and ribosome assembly YCR018C SRD1 nucleolar protein YCR035C RRP43 rRNA processing protein YDL014W NOP1 fibrillarin YDL111C RRP42 rRNA processing protein YDL208W NHP2 nucleolar rRNA processing protein YDR021W FAL1 involved in maturation of 18S rRNA YDR083W RRP8 protein involved in cleavage at site A2 in pre-rRNA in the pathway of ribosomal RNA processing YDR087C RRP1 involved in processing rRNA precursor species to mature rRNAs YDR280W RRP45 rRNA processing protein YDR432W NPL3 nucleolar protein YDR478W SNM1 RNA binding protein of RNase MRP YER127W LCP5 NGG1P interacting protein YFL002C SPB4 ATP-dependent RNA helicase of DEAH box family YGL078C DBP3 putative RNA helicase required for pre-rRNA processing YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL171W ROK1 ATP-dependent RNA helicase YGL173C KEM1 multifunctional nuclease YGR030C POP6 required for processing of tRNAs and rRNAs YGR095C RRP46 involved in rRNA processing YGR158C MTR3 involved in mRNA transport YGR159C NSR1 nuclear localization sequence binding protein YGR195W SKI6 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YHL034C SBP1 single-strand nucleic acid binding protein YHR062C RPP1 required for processing of tRNA and 35S rRNA YHR065C RRP3 required for maturation of the 35S primary transcript YHR069C RRP4 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YHR072W-A NOP10 nucleolar rRNA processing protein YHR089C GAR1 nucleolar rRNA processing protein YHR148W IMP3 component of the U3 small nucleolar ribonucleoprotein YJL033W HCA4 can suppress the U14 snoRNA rRNA processing function YJR002W MPP10 component of the U3 small nucleolar ribonucleoprotein YKL172W EBP2 required for pre-rRNA processing and ribosomal subunit assembly YKR024C DBP7 RNA helicase required for 60S ribosomal subunit assembly YLL008W DRS1 RNA helicase of the DEAD box family YLL011W SOF1 involved in 18S pre-rRNA production YLR059C REX2 putative 3'-5' exonuclease YLR175W CBF5 putative rRNA pseuduridine synthase YLR197W SIK1 involved in pre-rRNA processing YLR223C IFH1 pre-rRNA processing machinery control protein YMR229C RRP5 processing of pre-ribosomal RNA YMR235C RNA1 GTPase activating protein YMR239C RNT1 double-stranded ribonuclease YNL061W NOP2 nucleolar protein YNL075W IMP4 component of the U3 small nucleolar ribonucleoprotein YNL112W DBP2 ATP-dependent RNA helicase of DEAD box family YNL221C POP1 protein component of ribonuclease P and ribonuclease MRP YNL282W POP3 involved in processsing of tRNAs and rRNAs YNR038W DBP6 RNA helicase required for 60S ribosomal subunit assembly YOL021C DIS3 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YOR048C RAT1 5'-3' exoribonuclease YOR201C PET56 rRNA (guanosine-2'-O-)-methyltransferase YOR310C NOP58 required for pre-18S rRNA processing YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL043W NOP4 nucleolar protein YPL211W NIP7 required for efficient 60S ribosome subunit biogenesis YPL217C BMS1 GTP-binding protein, required for distinct steps of 40S ribosome biogenesis YPL266W DIM1 rRNA (adenine-N6,N6-)-dimethyltransferase other rRNA-transcription activities (6 ORFs) 04.01.99 6 YJL076W NET1 required for rDNA silencing and nucleolar integrity YKR019C IRS4 Increased rDNA silencing YMR131C RRB1 involved in the regulation of ribosome biosynthesis YMR302C PRP12 involved in early maturation of pre-rRNA YNL216W RAP1 DNA-binding protein with repressor and activator activity YOR294W RRS1 regulator of ribosome synthesis tRNA transcription (83 ORFs) 04.03 83 YAL001C TFC3 TFIIIC (transcription initiation factor) subunit, 138 kD YAL033W POP5 required for processing of tRNAs and rRNAs YAL043C PTA1 pre-tRNA processing protein / PF I subunit YAR008W SEN34 tRNA splicing endonuclease gamma subunit YBL013W FMT1 Methionyl-tRNA Transformylase YBL018C POP8 required for processing of tRNAs and rRNAs YBL024W NCL1 tRNA (cytosine-5-)-methyltransferase YBR123C TFC1 TFIIIC (transcription initiation factor) subunit, 95 kD YBR154C RPB5 DNA-directed RNA polymerase I, II, III 25 KD subunit YBR167C POP7 nuclear RNase P subunit YBR257W POP4 involved in processing of tRNAs and rRNAs YCR073W-A SOL2 multicopy suppressor of LOS1-1 YDL048C STP4 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YDL051W LHP1 RNA binding protein YDL112W TRM3 tRNA (guanosine-2'-O-)-methyltransferase YDL150W RPC53 DNA-directed RNA polymerase III, 47 KD subunit YDR120C TRM1 N2,N2-dimethylguanine tRNA methyltransferase YDR362C TFC6 TFIIIC (transcription initiation factor) subunit, 91 kD YDR381W YRA1 RNA annealing protein YDR395W SXM1 putative beta-karyopherin YDR463W STP1 pre-tRNA splicing protein, transcription factor YER148W SPT15 the TATA-binding protein TBP YER168C CCA1 tRNA nucleotidyltransferase YFL001W DEG1 pseudouridine synthase YGL019W CKB1 casein kinase II, beta subunit YGL063W PUS2 pseudouridine synthase 2 YGL092W NUP145 nuclear pore protein YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL105W ARC1 protein with specific affinity for G4 quadruplex nucleic acids YGL243W TAD1 tRNA-specific adenosine deaminase 1 YGR030C POP6 required for processing of tRNAs and rRNAs YGR047C TFC4 TFIIIC (transcription initiation factor) subunit, 131 kD YGR204W ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YGR246C BRF1 TFIIIB subunit, 70 kD YGR248W SOL4 strong similarity to SOL3P YHR006W STP2 involved in pre-tRNA splicing YHR062C RPP1 required for processing of tRNA and 35S rRNA YHR143W-A RPC10 DNA-directed RNA polymerases I, II, III 7.7 KD subunit YHR163W SOL3 possible 6-phosphogluconolactonase YIL035C CKA1 casein kinase II, catalytic alpha chain YIL075C RPN2 26S proteasome regulatory subunit YIR015W RPR2 RNase P subunit YJL035C TAD2 tRNA-specific adenosine deaminase 2 YJL041W NSP1 nuclear pore protein YJL087C TRL1 tRNA ligase YJR042W NUP85 nuclear pore protein YKL144C RPC25 DNA-direcred RNA polymerase III, 25 KD subunit YKL205W LOS1 pre-tRNA splicing protein YKR056W RNC1 tRNA(m5U54)methyltransferase YLR105C SEN2 tRNA splicing endonuclease beta subunit YLR136C TIS11 tRNA-specific adenosine deaminase 3 YLR316C TAD3 subunit of tRNA-specific adenosine-34 deaminase YLR375W STP3 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YLR430W SEN1 positive effector of tRNA-splicing endonuclease YML091C RPM2 ribonuclease P precursor, mitochondrial YMR047C NUP116 nuclear pore protein YMR059W SEN15 tRNA splicing endonuclease delta subunit YMR235C RNA1 GTPase activating protein YMR283C RIT1 initiator tRNA phosphoribosyl-transferase YNL039W BDP1 TFIIIB subunit, 90 kD YNL062C GCD10 translation initiation factor eIF3 RNA-binding subunit YNL113W RPC19 DNA-directed RNA polymerase I,III 16 KD subunit YNL151C RPC31 DNA-directed RNA polymerase III, 31 KD subunit YNL221C POP1 protein component of ribonuclease P and ribonuclease MRP YNL282W POP3 involved in processsing of tRNAs and rRNAs YNL292W PUS4 pseudouridine synthase YNR003C RPC34 DNA-directed RNA polymerase III, 34 KD subunit YNR034W SOL1 multicopy suppressor of LOS1-1 YOL102C TPT1 tRNA 2'-phosphotransferase YOR039W CKB2 casein kinase II beta' chain YOR061W CKA2 casein kinase II alpha' chain YOR110W TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa YOR116C RPO31 DNA-directed RNA polymerase III, 160 KD subunit YOR207C RET1 DNA-directed RNA polymerase III, 130 KD subunit YOR210W RPB10 DNA-directed polymerase I, II, III 8.3 subunit YOR224C RPB8 DNA-directed RNA polymerase I, II, III 16 KD subunit YOR274W MOD5 tRNA isopentenyltransferase YPL083C SEN54 tRNA splicing endonuclease alpha subunit YPL212C PUS1 pseudouridine synthase 1 YPR110C RPC40 DNA-directed RNA polymerase I, III 40 KD subunit YPR186C PZF1 TFIIIA (transcription initiation factor) YPR187W RPO26 DNA-directed RNA polymerase I, II, III 18 KD subunit YPR190C RPC82 DNA-directed RNA polymerase III, 82 KD subunit tRNA synthesis (24 ORFs) 04.03.01 24 YAL001C TFC3 TFIIIC (transcription initiation factor) subunit, 138 kD YBR123C TFC1 TFIIIC (transcription initiation factor) subunit, 95 kD YBR154C RPB5 DNA-directed RNA polymerase I, II, III 25 KD subunit YDL150W RPC53 DNA-directed RNA polymerase III, 47 KD subunit YDR362C TFC6 TFIIIC (transcription initiation factor) subunit, 91 kD YER148W SPT15 the TATA-binding protein TBP YGL019W CKB1 casein kinase II, beta subunit YGR047C TFC4 TFIIIC (transcription initiation factor) subunit, 131 kD YGR246C BRF1 TFIIIB subunit, 70 kD YHR143W-A RPC10 DNA-directed RNA polymerases I, II, III 7.7 KD subunit YKL144C RPC25 DNA-direcred RNA polymerase III, 25 KD subunit YNL039W BDP1 TFIIIB subunit, 90 kD YNL113W RPC19 DNA-directed RNA polymerase I,III 16 KD subunit YNL151C RPC31 DNA-directed RNA polymerase III, 31 KD subunit YNR003C RPC34 DNA-directed RNA polymerase III, 34 KD subunit YOR110W TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa YOR116C RPO31 DNA-directed RNA polymerase III, 160 KD subunit YOR207C RET1 DNA-directed RNA polymerase III, 130 KD subunit YOR210W RPB10 DNA-directed polymerase I, II, III 8.3 subunit YOR224C RPB8 DNA-directed RNA polymerase I, II, III 16 KD subunit YPR110C RPC40 DNA-directed RNA polymerase I, III 40 KD subunit YPR186C PZF1 TFIIIA (transcription initiation factor) YPR187W RPO26 DNA-directed RNA polymerase I, II, III 18 KD subunit YPR190C RPC82 DNA-directed RNA polymerase III, 82 KD subunit tRNA processing (36 ORFs) 04.03.03 36 YAL033W POP5 required for processing of tRNAs and rRNAs YAL043C PTA1 pre-tRNA processing protein / PF I subunit YAR008W SEN34 tRNA splicing endonuclease gamma subunit YBL018C POP8 required for processing of tRNAs and rRNAs YBR167C POP7 nuclear RNase P subunit YBR257W POP4 involved in processing of tRNAs and rRNAs YCR073W-A SOL2 multicopy suppressor of LOS1-1 YDL048C STP4 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YDR381W YRA1 RNA annealing protein YDR395W SXM1 putative beta-karyopherin YDR463W STP1 pre-tRNA splicing protein, transcription factor YGL092W NUP145 nuclear pore protein YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGR030C POP6 required for processing of tRNAs and rRNAs YGR248W SOL4 strong similarity to SOL3P YHR006W STP2 involved in pre-tRNA splicing YHR062C RPP1 required for processing of tRNA and 35S rRNA YHR163W SOL3 possible 6-phosphogluconolactonase YIL075C RPN2 26S proteasome regulatory subunit YIR015W RPR2 RNase P subunit YJL087C TRL1 tRNA ligase YJR042W NUP85 nuclear pore protein YKL205W LOS1 pre-tRNA splicing protein YLR105C SEN2 tRNA splicing endonuclease beta subunit YLR375W STP3 involved in pre-tRNA splicing and in uptake of branched-chain amino acids YLR430W SEN1 positive effector of tRNA-splicing endonuclease YML091C RPM2 ribonuclease P precursor, mitochondrial YMR047C NUP116 nuclear pore protein YMR059W SEN15 tRNA splicing endonuclease delta subunit YMR235C RNA1 GTPase activating protein YNL062C GCD10 translation initiation factor eIF3 RNA-binding subunit YNL221C POP1 protein component of ribonuclease P and ribonuclease MRP YNL282W POP3 involved in processsing of tRNAs and rRNAs YNR034W SOL1 multicopy suppressor of LOS1-1 YOL102C TPT1 tRNA 2'-phosphotransferase YPL083C SEN54 tRNA splicing endonuclease alpha subunit tRNA modification (18 ORFs) 04.03.06 18 YBL013W FMT1 Methionyl-tRNA Transformylase YBL024W NCL1 tRNA (cytosine-5-)-methyltransferase YDL112W TRM3 tRNA (guanosine-2'-O-)-methyltransferase YDR120C TRM1 N2,N2-dimethylguanine tRNA methyltransferase YER168C CCA1 tRNA nucleotidyltransferase YFL001W DEG1 pseudouridine synthase YGL063W PUS2 pseudouridine synthase 2 YGL105W ARC1 protein with specific affinity for G4 quadruplex nucleic acids YGL243W TAD1 tRNA-specific adenosine deaminase 1 YGR204W ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YJL035C TAD2 tRNA-specific adenosine deaminase 2 YKR056W RNC1 tRNA(m5U54)methyltransferase YLR136C TIS11 tRNA-specific adenosine deaminase 3 YLR316C TAD3 subunit of tRNA-specific adenosine-34 deaminase YMR283C RIT1 initiator tRNA phosphoribosyl-transferase YNL292W PUS4 pseudouridine synthase YOR274W MOD5 tRNA isopentenyltransferase YPL212C PUS1 pseudouridine synthase 1 other tRNA-transcription activities (4 ORFs) 04.03.99 4 YIL035C CKA1 casein kinase II, catalytic alpha chain YJL041W NSP1 nuclear pore protein YOR039W CKB2 casein kinase II beta' chain YOR061W CKA2 casein kinase II alpha' chain mRNA transcription (556 ORFs) 04.05 556 YAL021C CCR4 transcriptional regulator YAL032C PRP45 pre-mRNA splicing factor YAL043C PTA1 pre-tRNA processing protein / PF I subunit YAL051W OAF1 peroxisome proliferating transcription factor YAR003W SWD1 similarity to human RB protein binding protein YBL002W HTB2 histone H2B.2 YBL003C HTA2 histone H2A.2 YBL005W PDR3 pleiotropic drug resistance regulatory protein YBL008W HIR1 histone transcription regulator YBL021C HAP3 CCAAT-binding factor subunit YBL022C PIM1 ATP-dependent protease, mitochondrial YBL026W LSM2 Sm-like (Lsm) protein YBL052C SAS3 silencing protein YBL054W YBL054W weak similarity to transforming protein (B-myb) YBL066C SEF1 putative transcription factor YBL074C AAR2 A1 cistron splicing factor YBL093C ROX3 transcription factor YBL103C RTG3 bHLH/zip transcription factor that regulates CIT2 gene expression YBR009C HHF1 histone H4 YBR010W HHT1 histone H3 YBR020W GAL1 galactokinase YBR026C (MRF1) mitochondrial respiratory function protein YBR033W YBR033W weak similarity to transcription factors YBR045C GIP1 GLC7-interacting protein YBR049C REB1 transcription factor YBR055C PRP6 snRNP(U4/U6)-associated splicing factor YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR061C YBR061C similarity to E.coli ftsJ protein YBR081C SPT7 involved in alteration of transcription start site selection YBR083W TEC1 Ty transcription activator YBR103W SIF2 SIR4P interacting protein YBR112C CYC8 general repressor of transcription YBR119W MUD1 U1 snRNP-specific A protein YBR120C CBP6 apo-cytochrome B pre-mRNA processing protein YBR142W MAK5 ATP-dependent RNA helicase YBR152W SPP381 Suppressor of Pre-mRNA Processing mutant YBR154C RPB5 DNA-directed RNA polymerase I, II, III 25 KD subunit YBR182C SMP1 MADS-box transcription factor YBR188C NTC20 splicing factor YBR193C MED8 transcriptional regulation mediator YBR198C TAF90 TFIID and SAGA subunit YBR215W HPC2 cell cycle regulatory protein YBR236C ABD1 mRNA cap methyltransferase YBR237W PRP5 pre-mRNA processing RNA-helicase YBR240C THI2 regulator of the thiamine biosynthetic genes YBR245C ISW1 strong similarity to D.melanogaster iswi protein YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR275C RIF1 RAP1-interacting factor 1 YBR279W PAF1 DNA-directed RNA polymerase II regulator YBR289W SNF5 component of SWI/SNF transcription activator complex YBR297W MAL33 maltose fermentation regulatory protein YCL054W SPB1 required for ribosome synthesis, putative methylase YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCL066W HMLALPHA1 mating type regulatory protein, silenced copy at HML YCR020C PET18 similarity to regulatory protein YCR039C MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040W MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCR042C TSM1 component of TFIID complex YCR052W RSC6 subunit of the RSC complex YCR065W HCM1 transcription factor YCR077C PAT1 topoisomerase II-associated protein YCR081W SRB8 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YCR084C TUP1 general transcription repressor YCR093W CDC39 nuclear protein YCR106W YCR106W similarity to transcription factor YDL005C MED2 transcriptional regulation mediator YDL030W PRP9 pre-mRNA splicing factor (snRNA-associated protein) YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL043C PRP11 pre-mRNA splicing factor YDL044C MTF2 mitochondrial protein involved in mRNA splicing and protein synthesis YDL056W MBP1 transcription factor, subunit of the MBF factor YDL070W BDF2 similarity to bromodomain protein BDF1P YDL080C THI3 positive regulation factor of thiamin metabolism YDL084W SUB2 probably involved in pre-mRNA splicing YDL087C LUC7 yeast U1 snRNP protein with a role in 5' splice site recognition YDL098C SNU23 Putative RNA binding zinc finger protein YDL106C PHO2 homeodomain protein YDL108W KIN28 cyclin-dependent ser/thr protein kinase YDL140C RPO21 DNA-directed RNA polymerase II, 215 KD subunit YDL153C SAS10 involved in silencing YDL165W CDC36 transcription factor YDL170W UGA3 transcriptional activator for GABA catabolic genes YDL197C ASF2 anti-silencing protein YDL220C CDC13 cell division control protein YDR006C SOK1 high copy suppressor of a cyclic AMP-dependent protein kinase mutant YDR009W GAL3 galactokinase YDR017C KCS1 potential transcription factor of the BZIP type YDR026C YDR026C strong similarity to DNA-binding protein REB1P YDR028C REG1 regulatory subunit for protein phosphatase GLC7P YDR034C LYS14 transcriptional activator of lysine pathway genes YDR043C NRG1 transcriptional repressor for glucose repression of STA1 gene expression YDR045C RPC11 RNA polymerase III subunit C11, required for RNA cleavage activity and transcription termination YDR073W SNF11 component of SWI/SNF transcription activator complex YDR088C SLU7 pre-mRNA splicing factor affecting 3' splice site choice YDR121W DPB4 DNA polymerase II (epsilon) 4th subunit YDR123C INO2 basic helix-loop-helix (BHLH) transcription factor YDR138W HPR1 hyperrecombination protein related to TOP1P YDR145W TAF61 TFIID and SAGA subunit YDR146C SWI5 transcription factor YDR159W SAC3 leucine permease transcriptional regulator YDR160W SSY1 transcriptional regulator of several transporter genes YDR167W TAF25 TFIID and SAGA subunit YDR169C STB3 SIN3 protein-binding protein YDR173C ARG82 arginine metabolism transcription factor YDR176W NGG1 general transcriptional adaptor or co-activator YDR190C RVB1 RUVB-like protein YDR191W HST4 member of the SIR2P family of putative NAD-dependent histone deacetylases YDR194C MSS116 RNA helicase of the DEAD box family, mitochondrial YDR195W REF2 RNA 3'-end formation protein YDR207C UME6 negative transcriptional regulator YDR213W UPC2 regulatory protein involved in control of sterol uptake YDR216W ADR1 zinc-finger transcription factor YDR217C RAD9 DNA repair checkpoint protein YDR224C HTB1 histone H2B YDR225W HTA1 histone H2A YDR227W SIR4 silencing regulatory and DNA-repair protein YDR228C PCF11 component of pre-mRNA 3'-end processing factor CF I YDR235W PRP42 U1 snRNP associated protein, required for pre-mRNA splicing YDR240C SNU56 U1 snRNA protein, no counterpart in mammalian snRNP YDR243C PRP28 pre-mRNA splicing factor RNA helicase of DEAD box family YDR252W BTT1 alternate beta subunit of the nascent polypeptide-associated complex YDR253C MET32 transcriptional regulator of sulfur amino acid metabolism YDR257C RMS1 regulatory protein YDR259C YAP6 transcription factor, of a fungal-specific family of bzip proteins YDR301W CFT1 pre-mRNA 3'-end processing factor CF II YDR303C RSC3 similarity to transcriptional regulator proteins YDR308C SRB7 DNA-directed RNA polymerase II holoenzyme and kornberg's mediator (SRB) subcomplex subunit YDR310C SUM1 suppressor of SIR mutations YDR311W TFB1 TFIIH subunit (transcription initiation factor), 75 kD YDR334W SWR1 DEAH-box protein, putative RNA helicase YDR363W ESC2 involved in silencing YDR378C LSM6 Sm-like (Lsm) protein YDR390C UBA2 E1-like (ubiquitin-activating) enzyme YDR392W SPT3 general transcriptional adaptor or co-activator YDR397C NCB2 functional homolog of human NC2beta/Dr1 YDR404C RPB7 DNA-directed RNA polymerase II, 19 KD subunit YDR416W SYF1 synthetic lethal with CDC40 YDR421W ARO80 positive transcription regulator of ARO9 and ARO10 YDR423C CAD1 transcriptional activator YDR439W LRS4 involved in rDNA silencing YDR443C SSN2 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDR448W ADA2 general transcriptional adaptor or co-activator YDR460W TFB3 TFIIH subunit (transcription/repair factor) YDR463W STP1 pre-tRNA splicing protein, transcription factor YDR464W SPP41 negative regulator of PRP3 and PRP4 gene expression YDR473C PRP3 essential splicing factor YEL009C GCN4 transcriptional activator of amino acid biosynthetic genes YEL026W SNU13 component of the U4/U6.U5 snRNP YEL056W HAT2 subunit of the major yeast histone acetyltransferase YER013W PRP22 pre-mRNA splicing factor YER022W SRB4 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YER027C GAL83 glucose repression protein YER028C YER028C similarity to MIG1P YER029C SMB1 associated with U1 snRNP as part of the Sm-core that is common to all spliceosomal snRNPs YER032W FIR1 interacts with the poly(A) polymerase in the two hybrid system YER040W GLN3 transcription factor for positive nitrogen regulation YER045C ACA1 ATF/CREB activator YER068W MOT2 transcriptional repressor YER088C DOT6 involved in derepression of telomeric silencing YER109C FLO8 required for diploid filamentous growth YER111C SWI4 transcription factor YER112W LSM4 Sm-like (Lsm) protein YER120W SCS2 required for inositol metabolism YER122C GLO3 zinc finger protein YER130C YER130C similarity to MSN2P and weak similarity to MSN4P YER146W LSM5 Sm-like (Lsm) protein YER148W SPT15 the TATA-binding protein TBP YER151C UBP3 ubiquitin-specific proteinase YER159C BUR6 functional homolog of human NC2alpha YER161C SPT2 multifunctional HMG-like chromatin protein YER164W CHD1 transcriptional regulator YER165W PAB1 mRNA polyadenylate-binding protein YER169W RPH1 similarity to human retinoblastoma binding protein 2 YER171W RAD3 DNA helicase/ATPase YER172C BRR2 RNA helicase-related protein YER184C YER184C similarity to multidrug resistance proteins PDR3P and PDR1P YFL017W-A SMX2 snRNP G protein (the homologue of the human Sm-G) YFL021W GAT1 transcription factor for nitrogen regulation YFL028C CAF16 ATP-binding cassette transporter family member YFL031W HAC1 transcription factor YFL036W RPO41 DNA-directed RNA polymerase, mitochondrial YFL052W YFL052W strong similarity to Mal63p, YPR196w and MAL13P YFR005C SAD1 SnRNP assembly defective YFR029W PTR3 regulator of expression of the PTR2, GAP1 and BAP2 genes YFR034C PHO4 transcription factor YFR037C RSC8 subunit of the RSC complex YGL013C PDR1 transcription factor YGL025C PGD1 mediator complex subunit YGL035C MIG1 transcriptional repressor YGL043W DST1 TFIIS (transcription elongation factor) YGL044C RNA15 component of pre-mRNA 3'-end processing factor CF I YGL070C RPB9 DNA-directed RNA polymerase II, 14.2 KD subunit YGL071W RCS1 iron-regulated transcriptional repressor YGL073W HSF1 heat shock transcription factor YGL094C PAN2 component of PAB1P-stimulated poly(A) ribonuclease YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL112C TAF60 TFIID and SAGA subunit YGL115W SNF4 nuclear regulatory protein YGL120C PRP43 involved in spliceosome disassembly YGL122C NAB2 nuclear poly(A)-binding protein YGL130W CEG1 mRNA guanylyltransferase (mRNA capping enzyme, alpha subunit) YGL133W ITC1 subunit of ISW2 chromatin remodelling complex YGL141W HUL5 ubiquitin-protein ligase (E3) YGL150C INO80 similarity to SNF2P and human SNF2alpha YGL151W NUT1 negative transcription regulator from artifical reporters YGL166W CUP2 copper-dependent transcription factor YGL173C KEM1 multifunctional nuclease YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL192W IME4 positive transcription factor for IME2 YGL208W SIP2 dominant suppressor of some ts mutations in RPO21 and PRP4 YGL209W MIG2 C2H2 zinc-finger protein YGL221C NIF3 NGG1P-interacting factor 3 YGL237C HAP2 CCAAT-binding factor subunit YGL244W RTF1 regulates DNA binding properties of TBP YGL254W FZF1 sulfite resistance protein YGR005C TFG2 TFIIF subunit (transcription initiation factor), 54 kD YGR006W PRP18 U5 snRNA-associated protein YGR013W SNU71 associated with U1 snRNP, no counterpart in mammalian U1 snRNP YGR044C RME1 zinc-finger transcription factor YGR063C SPT4 transcription elongation protein YGR074W SMD1 snRNA-associated protein YGR075C PRP38 pre-mRNA splicing factor YGR091W PRP31 pre-mRNA splicing protein YGR092W DBF2 ser/thr protein kinase related to DBF20P YGR097W ASK10 involved in SKN7P-dependent transcription YGR100W MDR1 MAC1P interacting protein YGR104C SRB5 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YGR116W SPT6 transcription elongation protein YGR129W SYF2 synthetic lethal with CDC40 YGR158C MTR3 involved in mRNA transport YGR186W TFG1 TFIIF subunit (transcription initiation factor), 105 kD YGR200C ELP2 29 kDa subunit of elongator and elongating RNA polymerase II holoenzyme YGR222W PET54 splicing protein and translational activator, mitochondrial YGR249W MGA1 similarity to heat shock transcription factors YGR252W GCN5 histone acetyltransferase YGR274C TAF145 TFIID subunit (TBP-associated factor), 145 kD YGR288W MAL13 maltose pathway regulatory protein YHL009C YAP3 transcription factor, of a fungal-specific family of bzip proteins YHL020C OPI1 negative regulator of phospholipid biosynthesis pathway YHL025W SNF6 global transcription activator YHL027W RIM101 meiotic regulatory protein YHL038C CBP2 apo-cytochrome b pre-mRNA processing protein 2 YHR015W MIP6 similarity to PES4 a PAB-like protein YHR041C SRB2 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YHR056C RSC30 strong similarity to YHR054c YHR058C MED6 RNA polymerase II transcriptional regulation mediator YHR084W STE12 transcriptional activator YHR086W NAM8 meiotic recombination protein YHR099W TRA1 component of the Ada-Spt transcriptional regulatory complex YHR118C ORC6 origin recognition complex, 50 KD subunit YHR143W-A RPC10 DNA-directed RNA polymerases I, II, III 7.7 KD subunit YHR154W ESC4 Establishes Silent Chromatin YHR165C PRP8 U5 snRNP protein, pre-mRNA splicing factor YHR178W STB5 SIN3 binding protein YHR193C EGD2 alpha subunit of the nascent polypeptide-associated complex YHR206W SKN7 transcription factor with similarity to HSF1P YHR211W FLO5 member of the FLO1P family of flocculation proteins YIL010W DOT5 involved in derepression of telomeric silencing YIL021W RPB3 DNA-directed RNA-polymerase II, 45 kDa YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL036W CST6 ATF/CREB activator YIL038C NOT3 general negative regulator of transcription, subunit 3 YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL061C SNP1 U1 small nuclear ribonucleoprotein YIL084C SDS3 transcriptional regulator YIL101C XBP1 stress-induced transcriptional repressor YIL106W MOB1 required for completion of mitosis and maintenance of ploidy YIL126W STH1 subunit of the RSC complex YIL128W MET18 involved in NER repair and RNA polymerase II transcription YIL129C TAO3 Transcriptional Activator of OCH1 YIL130W YIL130W similarity to PUT3P and to hypothetical protein YJL206c YIL131C FKH1 forkhead protein, involved in transcriptional silencing, cell morphology and cell cycle YIL143C SSL2 DNA helicase YIR001C SGN1 similarity to D.melanogaster RNA binding protein YIR009W MSL1 U2 snRNA-associated protein with similarity to U2B YIR017C MET28 transcriptional activator of sulfur amino acid metabolism YIR018W YAP5 involved in transcription activation YIR021W MRS1 involved in mitochondrial RNA splicing of COB mRNA YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YJL006C CTK2 carboxy-terminal domain (CTD) kinase, beta subunit YJL056C ZAP1 metalloregulatory protein involved in zinc-responsive transcriptional regulation YJL089W SIP4 interacts with SNF1 protein kinase YJL103C YJL103C similarity to YBR239c YJL110C GZF3 transcriptional repressor YJL115W ASF1 anti-silencing protein YJL124C LSM1 Sm-like (Lsm) protein YJL127C SPT10 transcription regulatory protein YJL133W MRS3 RNA splicing protein and member of the mitochondrial carrier family (MCF) YJL140W RPB4 DNA-directed RNA polymerase II, 32 kDa subunit YJL164C TPK1 cAMP-dependent protein kinase 1, catalytic chain YJL176C SWI3 transcription regulatory protein YJL203W PRP21 pre-mRNA splicing factor YJL206C YJL206C similarity to YIL130p and PUT3P YJL209W CBP1 apo-cytochrome b pre-mRNA processing protein YJR017C ESS1 processing/termination factor 1 YJR022W LSM8 splicing factor YJR032W CPR7 member of the cyclophilin family YJR036C HUL4 hect domain E3 ubiquitin-protein ligase YJR050W ISY1 pre-mRNA splicing factor YJR060W CBF1 kinetochore protein YJR093C FIP1 component of pre-mRNA polyadenylation factor PF I YJR094C IME1 transcription factor required for sporulation YJR119C YJR119C similarity to human retinoblastoma binding protein 2 YJR122W CAF17 CCR4 associated factor YJR127C ZMS1 transcription factor with similarity to regulatory protein ARD1P YJR140C HIR3 involved in cell cycle regulation of histone transcription YJR147W HMS2 High-copy MEP2 Suppressor YKL009W MRT4 mRNA turnover 4 YKL012W PRP40 splicing factor YKL015W PUT3 positive activator of the proline utilisation pathway YKL025C PAN3 component of the PAB1P-dependent poly(A) ribonuclease YKL028W TFA1 TFIIE subunit (transcription initiation factor), 66 kD YKL032C IXR1 intrastrand crosslink recognition protein and transcription factor YKL038W RGT1 regulator of glucose-induced genes YKL043W PHD1 transcription factor YKL058W TOA2 TFIIA subunit (transcription initiation factor), 13.5 kD YKL062W MSN4 transcriptional activator YKL070W YKL070W similarity to B.subtilis transcriptional regulatory protein YKL072W STB6 SIN3 binding protein YKL074C MUD2 pre-mRNA splicing factor YKL078W DHR2 RNA helicase, involved in ribosomal RNA maturation YKL093W MBR1 required for optimal growth on glycerol YKL109W HAP4 CCAAT-binding factor subunit YKL112W ABF1 ARS-binding factor YKL139W CTK1 carboxy-terminal domain (CTD) kinase, alpha subunit YKL159C RCN1 inhibitor of calcineurin YKL166C TPK3 cAMP-dependent protein kinase 3, catalytic chain YKL185W ASH1 negative regulator of HO transcription YKL190W CNB1 calcineurin B, regulatory subunit YKL208W CBT1 apo-cytochrome b pre-mRNA processing protein YKL222C YKL222C weak similarity to transcription factors, similarity to finger proteins YOR162c, YOR172w and YLR266c YKR002W PAP1 poly(A) polymerase YKR025W RPC37 Pol III transcription YKR034W DAL80 transcriptional repressor for allantoin and GABA catabolic genes YKR036C CAF4 CCR4 associated factor YKR052C MRS4 RNA splicing protein and member of the mitochondrial carrier family (MCF) YKR062W TFA2 TFIIE subunit (transcription initiation factor), 43 KD YKR064W YKR064W weak similarity to transcription factors YKR072C SIS2 involved in cell cycle-specific gene expression YKR086W PRP16 RNA-dependent ATPase YKR099W BAS1 transcription factor YKR101W SIR1 silencing regulatory protein YLL004W ORC3 origin recognition complex, 62 kDa subunit YLL036C PRP19 non-snRNP sliceosome component required for DNA repair YLL054C YLL054C similarity to transcription factor PIP2P YLR005W SSL1 TFIIH subunit (transcription initiation factor), factor B YLR013W GAT3 weak similarity to nitrogen regulatory proteins YLR014C PPR1 transcription factor regulating pyrimidine pathway YLR039C RIC1 involved in transcription of ribosomal proteins and ribosomal RNA YLR055C SPT8 transcriptional adaptor or co-activator YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR098C CHA4 transcription factor YLR115W CFT2 cleavage and polyadenylation specificity factor, part of CF II YLR116W MSL5 branch point bridging protein YLR117C CLF1 strong similarity to Drosophila putative cell cycle control protein crn YLR131C ACE2 metallothionein expression activator YLR147C SMD3 spliceosomal snRNA-associated Sm core protein required for pre-mRNA splicing YLR176C RFX1 repressor of DNA damage-inducible genes YLR182W SWI6 transcription factor YLR192C HCR1 component of translation initiation factor eIF3, has similarity to human eIF3 p35 subunit YLR216C CPR6 member of the cyclophilin family YLR226W BUR2 divergent CDK-cyclin complex YLR228C ECM22 strong similarity to YDR213w, weak similarity to LYS14P YLR256W HAP1 transcription factor YLR266C YLR266C weak similarity to transcription factors YLR275W SMD2 U1 snRNP protein of the Sm class YLR277C YSH1 component of pre-mRNA polyadenylation factor PF I YLR278C YLR278C weak similarity to regulatory proteins YLR298C YHC1 associated with the U1 snRNP complex YLR321C SFH1 subunit of the RSC complex YLR382C NAM2 leucine--tRNA ligase precursor, mitochondrial YLR399C BDF1 sporulation protein YLR418C CDC73 DNA-directed RNA polymerase II accessory protein YLR433C CNA1 calcineurin B, catalytic subunit YLR438C-A LSM3 Sm-like (Lsm) protein YLR442C SIR3 silencing regulatory and DNA-repair protein YLR451W LEU3 transcription factor YML007W YAP1 transcriptional activator involved in oxidative stress response YML010W SPT5 transcription elongation protein YML015C TAF40 TFIID subunit (TBP-associated factor), 40KD YML046W PRP39 pre-mRNA splicing factor YML049C RSE1 involved in RNA splicing and ER to Golgi transport YML051W GAL80 negative regulator for expression of galactose-induced genes YML057W CMP2 calcineurin B, catalytic subunit YML065W ORC1 origin recognition complex, 104 KD subunit YML069W POB3 protein that binds to DNA polymerase I (PolI) YML076C YML076C weak similarity to transcription factor YML081W YML081W strong similarity to ZMS1 protein YML098W TAF19 TFIID subunit (TBP-associated factor), 19 kD YML099C ARG81 transcription factor involved in arginine metabolism YML112W CTK3 carboxy-terminal domain (CTD) kinase, gamma subunit YML114C TAF65 TBP Associated Factor 65 KDa YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR019W STB4 weak similarity to YIL130w, PUT3P and other transcription factors YMR021C MAC1 metal binding activator YMR023C MSS1 mitochondrial GTPase involved in expression of COX1 YMR037C MSN2 stress responsive regulatory protein YMR039C SUB1 transcriptional coactivator YMR042W ARG80 transcription factor involved in arginine metabolism YMR043W MCM1 transcription factor of the MADS box family YMR053C STB2 SIN3P binding protein YMR061W RNA14 component of pre-mRNA 3'-end processing factor CF I YMR070W MOT3 high-copy suppressor of MOT1-SPT3 synthetic lethality YMR112C MED11 mediator complex subunit YMR125W STO1 large subunit of the nuclear cap-binding protein complex CBC YMR127C SAS2 involved in silencing at HMR YMR139W RIM11 ser/thr protein kinase YMR179W SPT21 required for normal transcription at a number of loci YMR180C CTL1 RNA 5'-triphosphatase with manganese- or cobalt-dependent NTPase activities YMR182C RGM1 transcriptional repressor protein YMR227C TAF67 TFIID subunit (TBP-associated factor), 67 kD YMR228W MTF1 RNA polymerase specific factor, mitochondrial YMR236W TAF17 TFIID and SAGA subunit YMR240C CUS1 U2 snRNP protein YMR263W SAP30 subunit of the histone deacetylase B complex YMR268C PRP24 pre-mRNA splicing factor YMR277W FCP1 TFIIF interacting component of CTD phosphatase YMR280C CAT8 transcription factor involved in gluconeogenesis YMR287C MSU1 3'-5' exonuclease for RNA 3' ss-tail, mitochondrial YMR288W HSH155 component of a multiprotein splicing factor YMR312W ELP6 subunit of RNA polymerase II elongator complex YNL012W SPO1 transcriptional regulator involved in sporulation YNL016W PUB1 major polyadenylated RNA-binding protein of nucleus and cytoplasm YNL021W HDA1 histone deacetylase A YNL025C SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YNL027W CRZ1 calcineurin responsive zinc-finger YNL030W HHF2 histone H4 YNL031C HHT2 histone H3 YNL076W MKS1 pleiotropic regulatory factor YNL097C PHO23 involved in transcriptional regulation of PHO5 YNL103W MET4 transcriptional activator of sulfur metabolism YNL107W YAF9 similarity to human AF-9 protein YNL139C RLR1 regulatory protein YNL147W LSM7 Sm-like (Lsm) protein YNL167C SKO1 cre-binding bzip protein YNL186W UBP10 derepression of telomeric silencing YNL199C GCR2 glycolytic genes transcriptional activator YNL204C SPS18 sporulation-specific zinc-finger protein YNL210W MER1 meiotic recombination protein YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL222W SSU72 suppressor of cs mutant of SUA7 YNL236W SIN4 global regulator protein YNL251C NRD1 involved in regulation of nuclear pre-mRNA abundance YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL286W CUS2 cold sensitive U2 snRNA Suppressor YNL309W STB1 SIN3P binding protein YNL314W DAL82 transcriptional activator for allantoin catabolic genes YNL317W PFS2 polyadenylation factor I subunit 2 required for mRNA 3'-end processing, bridges two mRNA 3'-end processing factors YNL330C RPD3 histone deacetylase B YNR010W CSE2 subunit of RNA polymerase II mediator complex YNR011C PRP2 RNA-dependent ATPase of DEAH box family YNR023W SNF12 component of SWI/SNF global transcription activator complex YNR052C POP2 required for glucose derepression YOL001W PHO80 cyclin YOL004W SIN3 transcription regulatory protein YOL005C RPB11 DNA-directed RNA polymerase II subunit, 13.6 kD YOL028C YAP7 involved in transcription activation YOL042W NGL1 similarity to CCR4 protein YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL055C THI20 hydroxymethylpyrimidine phosphate (HMP-P) kinase YOL067C RTG1 basic helix-loop-helix transcription factor that regulates CIT2 gene expression YOL068C HST1 silencing protein YOL089C HAL9 transcriptional activator of ENA1 YOL108C INO4 basic helix-loop-helix transcription factor YOL116W MSN1 transcriptional activator YOL123W HRP1 CF Ib (RNA3' Cleavage factor Ib) YOL133W HRT1 similarity to Lotus RING-finger protein YOL135C MED7 member of RNA Polymerase II transcriptional regulation mediator complex YOL148C SPT20 member of the TBP class of SPT proteins that alter transcription site selection YOL149W DCP1 mRNA decapping enzyme YOR025W HST3 silencing protein YOR028C CIN5 transcriptional activator YOR038C HIR2 histone transcription regulator YOR047C STD1 dosage-dependent modulator of glucose repression YOR140W SFL1 transcription factor YOR148C SPP2 involved in pre-mRNA processing YOR151C RPB2 DNA-directed RNA polymerase II, 140 kDa chain YOR159C SME1 spliceosomal snRNA-associated Sm core protein required for mRNA splicing, also likely associated with telomerase TLC1 RNA YOR162C YRR1 transcription factor YOR174W MED4 transcription regulation mediator YOR179C YOR179C similarity to BRR5 protein YOR194C TOA1 TFIIA subunit (transcription initiation factor), 32 kD YOR204W DED1 ATP-dependent RNA helicase YOR210W RPB10 DNA-directed polymerase I, II, III 8.3 subunit YOR213C SAS5 subunit of the RSC complex YOR224C RPB8 DNA-directed RNA polymerase I, II, III 16 KD subunit YOR250C CLP1 cleavage/polyadenylation factor IA subunit YOR259C RPT4 26S proteasome regulatory subunit YOR290C SNF2 component of SWI/SNF global transcription activator complex YOR298C-A MBF1 multiprotein bridging factor mediates GCN4-dependent transcriptional activation YOR304W ISW2 strong similarity to Drosophila ISW1 and human SNF2P homolog YOR308C SNU66 component of U4/U6.U5 snRNP YOR319W HSH49 essential yeast splicing factor YOR334W MRS2 RNA splicing protein and member of the mitochondrial carrier family (MCF) YOR337W TEA1 TY1 enhancer activator YOR344C TYE7 basic helix-loop-helix transcription factor YOR358W HAP5 CCAAT-binding factor subunit YOR363C PIP2 peroxisome proliferating transcription factor YPL007C TFC8 RNA Polymerase III transcription initiation factor TFIIIC (tau), 60 kDa subunit YPL011C TAF47 component of the TBP-associated protein complex YPL015C HST2 similarity to HST1P and SIR2P YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL031C PHO85 cyclin-dependent protein kinase YPL037C EGD1 GAL4 DNA-binding enhancer protein YPL038W MET31 transcriptional regulator of sulfur amino acid metabolism YPL042C SSN3 cyclin-dependent CTD kinase YPL046C ELC1 Elongin C transcription elongation factor YPL060W LPE10 strong similarity to MRS2P YPL075W GCR1 transcriptional activator YPL082C MOT1 transcriptional accessory protein YPL089C RLM1 transcription factor of the MADS box family YPL101W ELP4 RNA polymerase II Elongator protein subunit YPL119C DBP1 ATP-dependent RNA helicase YPL122C TFB2 TFIIH subunit (transcription/repair factor) YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL139C UME1 negative regulator of meiosis YPL177C CUP9 involved in copper homeostasis repression of protein import YPL178W CBC2 small subunit of the nuclear cap-binding protein complex CBC YPL190C NAB3 polyadenylated RNA-binding protein YPL203W TPK2 cAMP-dependent protein kinase 2, catalytic chain YPL213W LEA1 U2 A' snRNP protein YPL228W CET1 RNA 5'-triphosphatase (mRNA capping enzyme, beta subunit) YPL248C GAL4 transcription factor YPL254W HFI1 transcriptional coactivator YPR025C CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPR056W TFB4 component of RNA polymerase transcription initiation TFIIH factor YPR057W BRR1 involved in snRNP biogenesis YPR065W ROX1 heme-dependent transcriptional repressor of hypoxic genes YPR068C HOS1 similarity to human histone deacetylase HD1 YPR070W MED1 component of RNA polymerase II holoenzyme and mediator subcomplex YPR072W NOT5 component of the NOT protein complex YPR086W SUA7 TFIIB subunit (transcription initiation factor), factor E YPR101W SNT309 splicing factor YPR104C FHL1 transcriptional activator of the forkhead/hnf3 family YPR107C YTH1 protein of the 3' processing complex YPR115W YPR115W similarity to probable transcription factor ASK10P, and to YNL047c and YIL105c YPR125W MRS7 suppressor of MRS2-1 mutation YPR134W MSS18 splicing protein YPR137W RRP9 protein associated with the U3 small nucleolar RNA, required for pre-ribosomal RNA processing YPR162C ORC4 origin recognition complex, 56 KD subunit YPR168W NUT2 negative transcription regulator from artifical reporters YPR178W PRP4 U4/U6 snRNP 52 KD protein YPR182W SMX3 snRNA-associated protein of the SM family YPR187W RPO26 DNA-directed RNA polymerase I, II, III 18 KD subunit YPR196W YPR196W strong similarity to regulatory protein Mal63p Q0050 AI1 COX1 intron 1 protein Q0055 AI2 COX1 intron 2 protein Q0060 AI3 DNA endonuclease Q0065 AI4 DNA endonuclease Q0070 AI5_ALPHA DNA endonuclease AI5_ALPHA Q0110 BI2 mRNA maturase BI2 Q0115 BI3 mRNA maturase BI3 Q0120 BI4 mRNA maturase BI4 Q0160 SCEI DNA endonuclease in 21S rRNA intron Q0255 Q0255 similarity to Podospora cytb intron 1a and coII intron protein 2 mRNA synthesis (406 ORFs) 04.05.01 406 YAL021C CCR4 transcriptional regulator YAL051W OAF1 peroxisome proliferating transcription factor YAR003W SWD1 similarity to human RB protein binding protein YBL002W HTB2 histone H2B.2 YBL003C HTA2 histone H2A.2 YBL005W PDR3 pleiotropic drug resistance regulatory protein YBL008W HIR1 histone transcription regulator YBL021C HAP3 CCAAT-binding factor subunit YBL052C SAS3 silencing protein YBL054W YBL054W weak similarity to transforming protein (B-myb) YBL066C SEF1 putative transcription factor YBL093C ROX3 transcription factor YBL103C RTG3 bHLH/zip transcription factor that regulates CIT2 gene expression YBR009C HHF1 histone H4 YBR010W HHT1 histone H3 YBR020W GAL1 galactokinase YBR026C (MRF1) mitochondrial respiratory function protein YBR033W YBR033W weak similarity to transcription factors YBR045C GIP1 GLC7-interacting protein YBR049C REB1 transcription factor YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR061C YBR061C similarity to E.coli ftsJ protein YBR081C SPT7 involved in alteration of transcription start site selection YBR083W TEC1 Ty transcription activator YBR103W SIF2 SIR4P interacting protein YBR112C CYC8 general repressor of transcription YBR154C RPB5 DNA-directed RNA polymerase I, II, III 25 KD subunit YBR182C SMP1 MADS-box transcription factor YBR193C MED8 transcriptional regulation mediator YBR198C TAF90 TFIID and SAGA subunit YBR215W HPC2 cell cycle regulatory protein YBR240C THI2 regulator of the thiamine biosynthetic genes YBR245C ISW1 strong similarity to D.melanogaster iswi protein YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR275C RIF1 RAP1-interacting factor 1 YBR279W PAF1 DNA-directed RNA polymerase II regulator YBR289W SNF5 component of SWI/SNF transcription activator complex YBR297W MAL33 maltose fermentation regulatory protein YCL054W SPB1 required for ribosome synthesis, putative methylase YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCL066W HMLALPHA1 mating type regulatory protein, silenced copy at HML YCR020C PET18 similarity to regulatory protein YCR039C MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040W MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCR042C TSM1 component of TFIID complex YCR052W RSC6 subunit of the RSC complex YCR065W HCM1 transcription factor YCR081W SRB8 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YCR084C TUP1 general transcription repressor YCR093W CDC39 nuclear protein YCR106W YCR106W similarity to transcription factor YDL005C MED2 transcriptional regulation mediator YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL056W MBP1 transcription factor, subunit of the MBF factor YDL070W BDF2 similarity to bromodomain protein BDF1P YDL080C THI3 positive regulation factor of thiamin metabolism YDL106C PHO2 homeodomain protein YDL108W KIN28 cyclin-dependent ser/thr protein kinase YDL140C RPO21 DNA-directed RNA polymerase II, 215 KD subunit YDL153C SAS10 involved in silencing YDL165W CDC36 transcription factor YDL170W UGA3 transcriptional activator for GABA catabolic genes YDL197C ASF2 anti-silencing protein YDL220C CDC13 cell division control protein YDR006C SOK1 high copy suppressor of a cyclic AMP-dependent protein kinase mutant YDR009W GAL3 galactokinase YDR017C KCS1 potential transcription factor of the BZIP type YDR026C YDR026C strong similarity to DNA-binding protein REB1P YDR034C LYS14 transcriptional activator of lysine pathway genes YDR043C NRG1 transcriptional repressor for glucose repression of STA1 gene expression YDR045C RPC11 RNA polymerase III subunit C11, required for RNA cleavage activity and transcription termination YDR073W SNF11 component of SWI/SNF transcription activator complex YDR121W DPB4 DNA polymerase II (epsilon) 4th subunit YDR123C INO2 basic helix-loop-helix (BHLH) transcription factor YDR138W HPR1 hyperrecombination protein related to TOP1P YDR145W TAF61 TFIID and SAGA subunit YDR146C SWI5 transcription factor YDR159W SAC3 leucine permease transcriptional regulator YDR160W SSY1 transcriptional regulator of several transporter genes YDR167W TAF25 TFIID and SAGA subunit YDR169C STB3 SIN3 protein-binding protein YDR173C ARG82 arginine metabolism transcription factor YDR176W NGG1 general transcriptional adaptor or co-activator YDR190C RVB1 RUVB-like protein YDR191W HST4 member of the SIR2P family of putative NAD-dependent histone deacetylases YDR207C UME6 negative transcriptional regulator YDR213W UPC2 regulatory protein involved in control of sterol uptake YDR216W ADR1 zinc-finger transcription factor YDR217C RAD9 DNA repair checkpoint protein YDR224C HTB1 histone H2B YDR225W HTA1 histone H2A YDR227W SIR4 silencing regulatory and DNA-repair protein YDR252W BTT1 alternate beta subunit of the nascent polypeptide-associated complex YDR253C MET32 transcriptional regulator of sulfur amino acid metabolism YDR257C RMS1 regulatory protein YDR259C YAP6 transcription factor, of a fungal-specific family of bzip proteins YDR303C RSC3 similarity to transcriptional regulator proteins YDR308C SRB7 DNA-directed RNA polymerase II holoenzyme and kornberg's mediator (SRB) subcomplex subunit YDR310C SUM1 suppressor of SIR mutations YDR311W TFB1 TFIIH subunit (transcription initiation factor), 75 kD YDR334W SWR1 DEAH-box protein, putative RNA helicase YDR363W ESC2 involved in silencing YDR392W SPT3 general transcriptional adaptor or co-activator YDR397C NCB2 functional homolog of human NC2beta/Dr1 YDR404C RPB7 DNA-directed RNA polymerase II, 19 KD subunit YDR421W ARO80 positive transcription regulator of ARO9 and ARO10 YDR423C CAD1 transcriptional activator YDR439W LRS4 involved in rDNA silencing YDR443C SSN2 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDR448W ADA2 general transcriptional adaptor or co-activator YDR460W TFB3 TFIIH subunit (transcription/repair factor) YDR463W STP1 pre-tRNA splicing protein, transcription factor YDR464W SPP41 negative regulator of PRP3 and PRP4 gene expression YEL009C GCN4 transcriptional activator of amino acid biosynthetic genes YEL056W HAT2 subunit of the major yeast histone acetyltransferase YER022W SRB4 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YER027C GAL83 glucose repression protein YER040W GLN3 transcription factor for positive nitrogen regulation YER045C ACA1 ATF/CREB activator YER068W MOT2 transcriptional repressor YER088C DOT6 involved in derepression of telomeric silencing YER109C FLO8 required for diploid filamentous growth YER111C SWI4 transcription factor YER120W SCS2 required for inositol metabolism YER122C GLO3 zinc finger protein YER130C YER130C similarity to MSN2P and weak similarity to MSN4P YER148W SPT15 the TATA-binding protein TBP YER151C UBP3 ubiquitin-specific proteinase YER159C BUR6 functional homolog of human NC2alpha YER161C SPT2 multifunctional HMG-like chromatin protein YER164W CHD1 transcriptional regulator YER169W RPH1 similarity to human retinoblastoma binding protein 2 YER171W RAD3 DNA helicase/ATPase YER184C YER184C similarity to multidrug resistance proteins PDR3P and PDR1P YFL021W GAT1 transcription factor for nitrogen regulation YFL028C CAF16 ATP-binding cassette transporter family member YFL031W HAC1 transcription factor YFL036W RPO41 DNA-directed RNA polymerase, mitochondrial YFL052W YFL052W strong similarity to Mal63p, YPR196w and MAL13P YFR029W PTR3 regulator of expression of the PTR2, GAP1 and BAP2 genes YFR034C PHO4 transcription factor YFR037C RSC8 subunit of the RSC complex YGL013C PDR1 transcription factor YGL025C PGD1 mediator complex subunit YGL035C MIG1 transcriptional repressor YGL043W DST1 TFIIS (transcription elongation factor) YGL070C RPB9 DNA-directed RNA polymerase II, 14.2 KD subunit YGL071W RCS1 iron-regulated transcriptional repressor YGL073W HSF1 heat shock transcription factor YGL112C TAF60 TFIID and SAGA subunit YGL115W SNF4 nuclear regulatory protein YGL133W ITC1 subunit of ISW2 chromatin remodelling complex YGL150C INO80 similarity to SNF2P and human SNF2alpha YGL151W NUT1 negative transcription regulator from artifical reporters YGL166W CUP2 copper-dependent transcription factor YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL192W IME4 positive transcription factor for IME2 YGL208W SIP2 dominant suppressor of some ts mutations in RPO21 and PRP4 YGL209W MIG2 C2H2 zinc-finger protein YGL221C NIF3 NGG1P-interacting factor 3 YGL237C HAP2 CCAAT-binding factor subunit YGL244W RTF1 regulates DNA binding properties of TBP YGL254W FZF1 sulfite resistance protein YGR005C TFG2 TFIIF subunit (transcription initiation factor), 54 kD YGR044C RME1 zinc-finger transcription factor YGR063C SPT4 transcription elongation protein YGR092W DBF2 ser/thr protein kinase related to DBF20P YGR097W ASK10 involved in SKN7P-dependent transcription YGR100W MDR1 MAC1P interacting protein YGR104C SRB5 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YGR116W SPT6 transcription elongation protein YGR186W TFG1 TFIIF subunit (transcription initiation factor), 105 kD YGR200C ELP2 29 kDa subunit of elongator and elongating RNA polymerase II holoenzyme YGR249W MGA1 similarity to heat shock transcription factors YGR252W GCN5 histone acetyltransferase YGR274C TAF145 TFIID subunit (TBP-associated factor), 145 kD YGR288W MAL13 maltose pathway regulatory protein YHL009C YAP3 transcription factor, of a fungal-specific family of bzip proteins YHL020C OPI1 negative regulator of phospholipid biosynthesis pathway YHL025W SNF6 global transcription activator YHL027W RIM101 meiotic regulatory protein YHR041C SRB2 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YHR056C RSC30 strong similarity to YHR054c YHR058C MED6 RNA polymerase II transcriptional regulation mediator YHR084W STE12 transcriptional activator YHR099W TRA1 component of the Ada-Spt transcriptional regulatory complex YHR118C ORC6 origin recognition complex, 50 KD subunit YHR143W-A RPC10 DNA-directed RNA polymerases I, II, III 7.7 KD subunit YHR154W ESC4 Establishes Silent Chromatin YHR178W STB5 SIN3 binding protein YHR193C EGD2 alpha subunit of the nascent polypeptide-associated complex YHR206W SKN7 transcription factor with similarity to HSF1P YHR211W FLO5 member of the FLO1P family of flocculation proteins YIL010W DOT5 involved in derepression of telomeric silencing YIL021W RPB3 DNA-directed RNA-polymerase II, 45 kDa YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL036W CST6 ATF/CREB activator YIL038C NOT3 general negative regulator of transcription, subunit 3 YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL084C SDS3 transcriptional regulator YIL101C XBP1 stress-induced transcriptional repressor YIL106W MOB1 required for completion of mitosis and maintenance of ploidy YIL126W STH1 subunit of the RSC complex YIL128W MET18 involved in NER repair and RNA polymerase II transcription YIL129C TAO3 Transcriptional Activator of OCH1 YIL130W YIL130W similarity to PUT3P and to hypothetical protein YJL206c YIL131C FKH1 forkhead protein, involved in transcriptional silencing, cell morphology and cell cycle YIL143C SSL2 DNA helicase YIR017C MET28 transcriptional activator of sulfur amino acid metabolism YIR018W YAP5 involved in transcription activation YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YJL006C CTK2 carboxy-terminal domain (CTD) kinase, beta subunit YJL056C ZAP1 metalloregulatory protein involved in zinc-responsive transcriptional regulation YJL089W SIP4 interacts with SNF1 protein kinase YJL103C YJL103C similarity to YBR239c YJL110C GZF3 transcriptional repressor YJL115W ASF1 anti-silencing protein YJL127C SPT10 transcription regulatory protein YJL140W RPB4 DNA-directed RNA polymerase II, 32 kDa subunit YJL164C TPK1 cAMP-dependent protein kinase 1, catalytic chain YJL176C SWI3 transcription regulatory protein YJL206C YJL206C similarity to YIL130p and PUT3P YJR032W CPR7 member of the cyclophilin family YJR060W CBF1 kinetochore protein YJR094C IME1 transcription factor required for sporulation YJR119C YJR119C similarity to human retinoblastoma binding protein 2 YJR122W CAF17 CCR4 associated factor YJR140C HIR3 involved in cell cycle regulation of histone transcription YJR147W HMS2 High-copy MEP2 Suppressor YKL015W PUT3 positive activator of the proline utilisation pathway YKL028W TFA1 TFIIE subunit (transcription initiation factor), 66 kD YKL032C IXR1 intrastrand crosslink recognition protein and transcription factor YKL038W RGT1 regulator of glucose-induced genes YKL043W PHD1 transcription factor YKL058W TOA2 TFIIA subunit (transcription initiation factor), 13.5 kD YKL062W MSN4 transcriptional activator YKL070W YKL070W similarity to B.subtilis transcriptional regulatory protein YKL072W STB6 SIN3 binding protein YKL093W MBR1 required for optimal growth on glycerol YKL109W HAP4 CCAAT-binding factor subunit YKL112W ABF1 ARS-binding factor YKL139W CTK1 carboxy-terminal domain (CTD) kinase, alpha subunit YKL159C RCN1 inhibitor of calcineurin YKL166C TPK3 cAMP-dependent protein kinase 3, catalytic chain YKL185W ASH1 negative regulator of HO transcription YKL190W CNB1 calcineurin B, regulatory subunit YKL222C YKL222C weak similarity to transcription factors, similarity to finger proteins YOR162c, YOR172w and YLR266c YKR025W RPC37 Pol III transcription YKR034W DAL80 transcriptional repressor for allantoin and GABA catabolic genes YKR036C CAF4 CCR4 associated factor YKR062W TFA2 TFIIE subunit (transcription initiation factor), 43 KD YKR064W YKR064W weak similarity to transcription factors YKR072C SIS2 involved in cell cycle-specific gene expression YKR099W BAS1 transcription factor YKR101W SIR1 silencing regulatory protein YLL004W ORC3 origin recognition complex, 62 kDa subunit YLL054C YLL054C similarity to transcription factor PIP2P YLR005W SSL1 TFIIH subunit (transcription initiation factor), factor B YLR013W GAT3 weak similarity to nitrogen regulatory proteins YLR014C PPR1 transcription factor regulating pyrimidine pathway YLR039C RIC1 involved in transcription of ribosomal proteins and ribosomal RNA YLR055C SPT8 transcriptional adaptor or co-activator YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR098C CHA4 transcription factor YLR131C ACE2 metallothionein expression activator YLR176C RFX1 repressor of DNA damage-inducible genes YLR182W SWI6 transcription factor YLR192C HCR1 component of translation initiation factor eIF3, has similarity to human eIF3 p35 subunit YLR216C CPR6 member of the cyclophilin family YLR226W BUR2 divergent CDK-cyclin complex YLR228C ECM22 strong similarity to YDR213w, weak similarity to LYS14P YLR256W HAP1 transcription factor YLR266C YLR266C weak similarity to transcription factors YLR278C YLR278C weak similarity to regulatory proteins YLR321C SFH1 subunit of the RSC complex YLR399C BDF1 sporulation protein YLR418C CDC73 DNA-directed RNA polymerase II accessory protein YLR433C CNA1 calcineurin B, catalytic subunit YLR442C SIR3 silencing regulatory and DNA-repair protein YLR451W LEU3 transcription factor YML007W YAP1 transcriptional activator involved in oxidative stress response YML010W SPT5 transcription elongation protein YML015C TAF40 TFIID subunit (TBP-associated factor), 40KD YML051W GAL80 negative regulator for expression of galactose-induced genes YML057W CMP2 calcineurin B, catalytic subunit YML065W ORC1 origin recognition complex, 104 KD subunit YML076C YML076C weak similarity to transcription factor YML081W YML081W strong similarity to ZMS1 protein YML098W TAF19 TFIID subunit (TBP-associated factor), 19 kD YML099C ARG81 transcription factor involved in arginine metabolism YML112W CTK3 carboxy-terminal domain (CTD) kinase, gamma subunit YML114C TAF65 TBP Associated Factor 65 KDa YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR019W STB4 weak similarity to YIL130w, PUT3P and other transcription factors YMR021C MAC1 metal binding activator YMR037C MSN2 stress responsive regulatory protein YMR039C SUB1 transcriptional coactivator YMR042W ARG80 transcription factor involved in arginine metabolism YMR043W MCM1 transcription factor of the MADS box family YMR053C STB2 SIN3P binding protein YMR061W RNA14 component of pre-mRNA 3'-end processing factor CF I YMR070W MOT3 high-copy suppressor of MOT1-SPT3 synthetic lethality YMR112C MED11 mediator complex subunit YMR127C SAS2 involved in silencing at HMR YMR139W RIM11 ser/thr protein kinase YMR179W SPT21 required for normal transcription at a number of loci YMR182C RGM1 transcriptional repressor protein YMR227C TAF67 TFIID subunit (TBP-associated factor), 67 kD YMR228W MTF1 RNA polymerase specific factor, mitochondrial YMR236W TAF17 TFIID and SAGA subunit YMR263W SAP30 subunit of the histone deacetylase B complex YMR277W FCP1 TFIIF interacting component of CTD phosphatase YMR280C CAT8 transcription factor involved in gluconeogenesis YMR312W ELP6 subunit of RNA polymerase II elongator complex YNL012W SPO1 transcriptional regulator involved in sporulation YNL021W HDA1 histone deacetylase A YNL025C SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YNL027W CRZ1 calcineurin responsive zinc-finger YNL030W HHF2 histone H4 YNL031C HHT2 histone H3 YNL076W MKS1 pleiotropic regulatory factor YNL097C PHO23 involved in transcriptional regulation of PHO5 YNL103W MET4 transcriptional activator of sulfur metabolism YNL107W YAF9 similarity to human AF-9 protein YNL139C RLR1 regulatory protein YNL167C SKO1 cre-binding bzip protein YNL186W UBP10 derepression of telomeric silencing YNL199C GCR2 glycolytic genes transcriptional activator YNL204C SPS18 sporulation-specific zinc-finger protein YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL222W SSU72 suppressor of cs mutant of SUA7 YNL236W SIN4 global regulator protein YNL251C NRD1 involved in regulation of nuclear pre-mRNA abundance YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL309W STB1 SIN3P binding protein YNL314W DAL82 transcriptional activator for allantoin catabolic genes YNL330C RPD3 histone deacetylase B YNR010W CSE2 subunit of RNA polymerase II mediator complex YNR023W SNF12 component of SWI/SNF global transcription activator complex YNR052C POP2 required for glucose derepression YOL001W PHO80 cyclin YOL004W SIN3 transcription regulatory protein YOL005C RPB11 DNA-directed RNA polymerase II subunit, 13.6 kD YOL028C YAP7 involved in transcription activation YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL055C THI20 hydroxymethylpyrimidine phosphate (HMP-P) kinase YOL067C RTG1 basic helix-loop-helix transcription factor that regulates CIT2 gene expression YOL068C HST1 silencing protein YOL089C HAL9 transcriptional activator of ENA1 YOL108C INO4 basic helix-loop-helix transcription factor YOL116W MSN1 transcriptional activator YOL133W HRT1 similarity to Lotus RING-finger protein YOL135C MED7 member of RNA Polymerase II transcriptional regulation mediator complex YOL148C SPT20 member of the TBP class of SPT proteins that alter transcription site selection YOR025W HST3 silencing protein YOR028C CIN5 transcriptional activator YOR038C HIR2 histone transcription regulator YOR047C STD1 dosage-dependent modulator of glucose repression YOR140W SFL1 transcription factor YOR151C RPB2 DNA-directed RNA polymerase II, 140 kDa chain YOR162C YRR1 transcription factor YOR174W MED4 transcription regulation mediator YOR194C TOA1 TFIIA subunit (transcription initiation factor), 32 kD YOR210W RPB10 DNA-directed polymerase I, II, III 8.3 subunit YOR213C SAS5 subunit of the RSC complex YOR224C RPB8 DNA-directed RNA polymerase I, II, III 16 KD subunit YOR259C RPT4 26S proteasome regulatory subunit YOR290C SNF2 component of SWI/SNF global transcription activator complex YOR298C-A MBF1 multiprotein bridging factor mediates GCN4-dependent transcriptional activation YOR304W ISW2 strong similarity to Drosophila ISW1 and human SNF2P homolog YOR337W TEA1 TY1 enhancer activator YOR344C TYE7 basic helix-loop-helix transcription factor YOR358W HAP5 CCAAT-binding factor subunit YOR363C PIP2 peroxisome proliferating transcription factor YPL007C TFC8 RNA Polymerase III transcription initiation factor TFIIIC (tau), 60 kDa subunit YPL011C TAF47 component of the TBP-associated protein complex YPL015C HST2 similarity to HST1P and SIR2P YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL031C PHO85 cyclin-dependent protein kinase YPL037C EGD1 GAL4 DNA-binding enhancer protein YPL038W MET31 transcriptional regulator of sulfur amino acid metabolism YPL042C SSN3 cyclin-dependent CTD kinase YPL046C ELC1 Elongin C transcription elongation factor YPL075W GCR1 transcriptional activator YPL082C MOT1 transcriptional accessory protein YPL089C RLM1 transcription factor of the MADS box family YPL101W ELP4 RNA polymerase II Elongator protein subunit YPL122C TFB2 TFIIH subunit (transcription/repair factor) YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL139C UME1 negative regulator of meiosis YPL177C CUP9 involved in copper homeostasis repression of protein import YPL203W TPK2 cAMP-dependent protein kinase 2, catalytic chain YPL248C GAL4 transcription factor YPL254W HFI1 transcriptional coactivator YPR025C CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPR056W TFB4 component of RNA polymerase transcription initiation TFIIH factor YPR065W ROX1 heme-dependent transcriptional repressor of hypoxic genes YPR070W MED1 component of RNA polymerase II holoenzyme and mediator subcomplex YPR072W NOT5 component of the NOT protein complex YPR086W SUA7 TFIIB subunit (transcription initiation factor), factor E YPR104C FHL1 transcriptional activator of the forkhead/hnf3 family YPR115W YPR115W similarity to probable transcription factor ASK10P, and to YNL047c and YIL105c YPR162C ORC4 origin recognition complex, 56 KD subunit YPR168W NUT2 negative transcription regulator from artifical reporters YPR187W RPO26 DNA-directed RNA polymerase I, II, III 18 KD subunit YPR196W YPR196W strong similarity to regulatory protein Mal63p general transcription activities (68 ORFs) 04.05.01.01 68 YBR154C RPB5 DNA-directed RNA polymerase I, II, III 25 KD subunit YBR198C TAF90 TFIID and SAGA subunit YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YCR042C TSM1 component of TFIID complex YCR081W SRB8 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDL108W KIN28 cyclin-dependent ser/thr protein kinase YDL140C RPO21 DNA-directed RNA polymerase II, 215 KD subunit YDR045C RPC11 RNA polymerase III subunit C11, required for RNA cleavage activity and transcription termination YDR121W DPB4 DNA polymerase II (epsilon) 4th subunit YDR145W TAF61 TFIID and SAGA subunit YDR167W TAF25 TFIID and SAGA subunit YDR190C RVB1 RUVB-like protein YDR308C SRB7 DNA-directed RNA polymerase II holoenzyme and kornberg's mediator (SRB) subcomplex subunit YDR311W TFB1 TFIIH subunit (transcription initiation factor), 75 kD YDR404C RPB7 DNA-directed RNA polymerase II, 19 KD subunit YDR443C SSN2 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDR460W TFB3 TFIIH subunit (transcription/repair factor) YER022W SRB4 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YER148W SPT15 the TATA-binding protein TBP YER171W RAD3 DNA helicase/ATPase YFL036W RPO41 DNA-directed RNA polymerase, mitochondrial YGL043W DST1 TFIIS (transcription elongation factor) YGL070C RPB9 DNA-directed RNA polymerase II, 14.2 KD subunit YGL112C TAF60 TFIID and SAGA subunit YGL244W RTF1 regulates DNA binding properties of TBP YGR005C TFG2 TFIIF subunit (transcription initiation factor), 54 kD YGR063C SPT4 transcription elongation protein YGR104C SRB5 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YGR116W SPT6 transcription elongation protein YGR186W TFG1 TFIIF subunit (transcription initiation factor), 105 kD YGR200C ELP2 29 kDa subunit of elongator and elongating RNA polymerase II holoenzyme YGR274C TAF145 TFIID subunit (TBP-associated factor), 145 kD YHR041C SRB2 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YHR143W-A RPC10 DNA-directed RNA polymerases I, II, III 7.7 KD subunit YIL021W RPB3 DNA-directed RNA-polymerase II, 45 kDa YIL143C SSL2 DNA helicase YJL140W RPB4 DNA-directed RNA polymerase II, 32 kDa subunit YKL028W TFA1 TFIIE subunit (transcription initiation factor), 66 kD YKL058W TOA2 TFIIA subunit (transcription initiation factor), 13.5 kD YKR062W TFA2 TFIIE subunit (transcription initiation factor), 43 KD YLR005W SSL1 TFIIH subunit (transcription initiation factor), factor B YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YML010W SPT5 transcription elongation protein YML015C TAF40 TFIID subunit (TBP-associated factor), 40KD YML098W TAF19 TFIID subunit (TBP-associated factor), 19 kD YML114C TAF65 TBP Associated Factor 65 KDa YMR112C MED11 mediator complex subunit YMR227C TAF67 TFIID subunit (TBP-associated factor), 67 kD YMR228W MTF1 RNA polymerase specific factor, mitochondrial YMR236W TAF17 TFIID and SAGA subunit YMR312W ELP6 subunit of RNA polymerase II elongator complex YNL025C SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YNR010W CSE2 subunit of RNA polymerase II mediator complex YOL005C RPB11 DNA-directed RNA polymerase II subunit, 13.6 kD YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOR151C RPB2 DNA-directed RNA polymerase II, 140 kDa chain YOR194C TOA1 TFIIA subunit (transcription initiation factor), 32 kD YOR210W RPB10 DNA-directed polymerase I, II, III 8.3 subunit YOR224C RPB8 DNA-directed RNA polymerase I, II, III 16 KD subunit YPL011C TAF47 component of the TBP-associated protein complex YPL046C ELC1 Elongin C transcription elongation factor YPL122C TFB2 TFIIH subunit (transcription/repair factor) YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPR025C CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPR056W TFB4 component of RNA polymerase transcription initiation TFIIH factor YPR070W MED1 component of RNA polymerase II holoenzyme and mediator subcomplex YPR086W SUA7 TFIIB subunit (transcription initiation factor), factor E YPR187W RPO26 DNA-directed RNA polymerase I, II, III 18 KD subunit transcriptional control (334 ORFs) 04.05.01.04 334 YAL021C CCR4 transcriptional regulator YAL051W OAF1 peroxisome proliferating transcription factor YAR003W SWD1 similarity to human RB protein binding protein YBL002W HTB2 histone H2B.2 YBL003C HTA2 histone H2A.2 YBL005W PDR3 pleiotropic drug resistance regulatory protein YBL008W HIR1 histone transcription regulator YBL021C HAP3 CCAAT-binding factor subunit YBL052C SAS3 silencing protein YBL054W YBL054W weak similarity to transforming protein (B-myb) YBL066C SEF1 putative transcription factor YBL093C ROX3 transcription factor YBL103C RTG3 bHLH/zip transcription factor that regulates CIT2 gene expression YBR009C HHF1 histone H4 YBR010W HHT1 histone H3 YBR020W GAL1 galactokinase YBR026C (MRF1) mitochondrial respiratory function protein YBR033W YBR033W weak similarity to transcription factors YBR045C GIP1 GLC7-interacting protein YBR049C REB1 transcription factor YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR061C YBR061C similarity to E.coli ftsJ protein YBR081C SPT7 involved in alteration of transcription start site selection YBR083W TEC1 Ty transcription activator YBR103W SIF2 SIR4P interacting protein YBR112C CYC8 general repressor of transcription YBR182C SMP1 MADS-box transcription factor YBR198C TAF90 TFIID and SAGA subunit YBR215W HPC2 cell cycle regulatory protein YBR240C THI2 regulator of the thiamine biosynthetic genes YBR245C ISW1 strong similarity to D.melanogaster iswi protein YBR275C RIF1 RAP1-interacting factor 1 YBR279W PAF1 DNA-directed RNA polymerase II regulator YBR289W SNF5 component of SWI/SNF transcription activator complex YBR297W MAL33 maltose fermentation regulatory protein YCL054W SPB1 required for ribosome synthesis, putative methylase YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCL066W HMLALPHA1 mating type regulatory protein, silenced copy at HML YCR020C PET18 similarity to regulatory protein YCR039C MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040W MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCR042C TSM1 component of TFIID complex YCR052W RSC6 subunit of the RSC complex YCR065W HCM1 transcription factor YCR084C TUP1 general transcription repressor YCR093W CDC39 nuclear protein YCR106W YCR106W similarity to transcription factor YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL056W MBP1 transcription factor, subunit of the MBF factor YDL070W BDF2 similarity to bromodomain protein BDF1P YDL080C THI3 positive regulation factor of thiamin metabolism YDL106C PHO2 homeodomain protein YDL153C SAS10 involved in silencing YDL165W CDC36 transcription factor YDL170W UGA3 transcriptional activator for GABA catabolic genes YDL197C ASF2 anti-silencing protein YDL220C CDC13 cell division control protein YDR006C SOK1 high copy suppressor of a cyclic AMP-dependent protein kinase mutant YDR009W GAL3 galactokinase YDR017C KCS1 potential transcription factor of the BZIP type YDR026C YDR026C strong similarity to DNA-binding protein REB1P YDR034C LYS14 transcriptional activator of lysine pathway genes YDR043C NRG1 transcriptional repressor for glucose repression of STA1 gene expression YDR073W SNF11 component of SWI/SNF transcription activator complex YDR123C INO2 basic helix-loop-helix (BHLH) transcription factor YDR138W HPR1 hyperrecombination protein related to TOP1P YDR145W TAF61 TFIID and SAGA subunit YDR146C SWI5 transcription factor YDR159W SAC3 leucine permease transcriptional regulator YDR160W SSY1 transcriptional regulator of several transporter genes YDR167W TAF25 TFIID and SAGA subunit YDR169C STB3 SIN3 protein-binding protein YDR173C ARG82 arginine metabolism transcription factor YDR176W NGG1 general transcriptional adaptor or co-activator YDR191W HST4 member of the SIR2P family of putative NAD-dependent histone deacetylases YDR207C UME6 negative transcriptional regulator YDR213W UPC2 regulatory protein involved in control of sterol uptake YDR216W ADR1 zinc-finger transcription factor YDR217C RAD9 DNA repair checkpoint protein YDR224C HTB1 histone H2B YDR225W HTA1 histone H2A YDR227W SIR4 silencing regulatory and DNA-repair protein YDR252W BTT1 alternate beta subunit of the nascent polypeptide-associated complex YDR253C MET32 transcriptional regulator of sulfur amino acid metabolism YDR257C RMS1 regulatory protein YDR259C YAP6 transcription factor, of a fungal-specific family of bzip proteins YDR303C RSC3 similarity to transcriptional regulator proteins YDR310C SUM1 suppressor of SIR mutations YDR334W SWR1 DEAH-box protein, putative RNA helicase YDR363W ESC2 involved in silencing YDR392W SPT3 general transcriptional adaptor or co-activator YDR397C NCB2 functional homolog of human NC2beta/Dr1 YDR421W ARO80 positive transcription regulator of ARO9 and ARO10 YDR423C CAD1 transcriptional activator YDR439W LRS4 involved in rDNA silencing YDR448W ADA2 general transcriptional adaptor or co-activator YDR463W STP1 pre-tRNA splicing protein, transcription factor YDR464W SPP41 negative regulator of PRP3 and PRP4 gene expression YEL009C GCN4 transcriptional activator of amino acid biosynthetic genes YEL056W HAT2 subunit of the major yeast histone acetyltransferase YER027C GAL83 glucose repression protein YER040W GLN3 transcription factor for positive nitrogen regulation YER045C ACA1 ATF/CREB activator YER068W MOT2 transcriptional repressor YER088C DOT6 involved in derepression of telomeric silencing YER109C FLO8 required for diploid filamentous growth YER111C SWI4 transcription factor YER120W SCS2 required for inositol metabolism YER122C GLO3 zinc finger protein YER130C YER130C similarity to MSN2P and weak similarity to MSN4P YER151C UBP3 ubiquitin-specific proteinase YER159C BUR6 functional homolog of human NC2alpha YER161C SPT2 multifunctional HMG-like chromatin protein YER164W CHD1 transcriptional regulator YER169W RPH1 similarity to human retinoblastoma binding protein 2 YER184C YER184C similarity to multidrug resistance proteins PDR3P and PDR1P YFL021W GAT1 transcription factor for nitrogen regulation YFL028C CAF16 ATP-binding cassette transporter family member YFL031W HAC1 transcription factor YFL052W YFL052W strong similarity to Mal63p, YPR196w and MAL13P YFR029W PTR3 regulator of expression of the PTR2, GAP1 and BAP2 genes YFR034C PHO4 transcription factor YFR037C RSC8 subunit of the RSC complex YGL013C PDR1 transcription factor YGL025C PGD1 mediator complex subunit YGL035C MIG1 transcriptional repressor YGL071W RCS1 iron-regulated transcriptional repressor YGL073W HSF1 heat shock transcription factor YGL112C TAF60 TFIID and SAGA subunit YGL115W SNF4 nuclear regulatory protein YGL133W ITC1 subunit of ISW2 chromatin remodelling complex YGL150C INO80 similarity to SNF2P and human SNF2alpha YGL151W NUT1 negative transcription regulator from artifical reporters YGL166W CUP2 copper-dependent transcription factor YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL192W IME4 positive transcription factor for IME2 YGL208W SIP2 dominant suppressor of some ts mutations in RPO21 and PRP4 YGL209W MIG2 C2H2 zinc-finger protein YGL221C NIF3 NGG1P-interacting factor 3 YGL237C HAP2 CCAAT-binding factor subunit YGL254W FZF1 sulfite resistance protein YGR044C RME1 zinc-finger transcription factor YGR092W DBF2 ser/thr protein kinase related to DBF20P YGR097W ASK10 involved in SKN7P-dependent transcription YGR100W MDR1 MAC1P interacting protein YGR249W MGA1 similarity to heat shock transcription factors YGR252W GCN5 histone acetyltransferase YGR288W MAL13 maltose pathway regulatory protein YHL009C YAP3 transcription factor, of a fungal-specific family of bzip proteins YHL020C OPI1 negative regulator of phospholipid biosynthesis pathway YHL025W SNF6 global transcription activator YHL027W RIM101 meiotic regulatory protein YHR056C RSC30 strong similarity to YHR054c YHR058C MED6 RNA polymerase II transcriptional regulation mediator YHR084W STE12 transcriptional activator YHR099W TRA1 component of the Ada-Spt transcriptional regulatory complex YHR118C ORC6 origin recognition complex, 50 KD subunit YHR154W ESC4 Establishes Silent Chromatin YHR178W STB5 SIN3 binding protein YHR193C EGD2 alpha subunit of the nascent polypeptide-associated complex YHR206W SKN7 transcription factor with similarity to HSF1P YHR211W FLO5 member of the FLO1P family of flocculation proteins YIL010W DOT5 involved in derepression of telomeric silencing YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL036W CST6 ATF/CREB activator YIL038C NOT3 general negative regulator of transcription, subunit 3 YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL084C SDS3 transcriptional regulator YIL101C XBP1 stress-induced transcriptional repressor YIL106W MOB1 required for completion of mitosis and maintenance of ploidy YIL126W STH1 subunit of the RSC complex YIL128W MET18 involved in NER repair and RNA polymerase II transcription YIL129C TAO3 Transcriptional Activator of OCH1 YIL130W YIL130W similarity to PUT3P and to hypothetical protein YJL206c YIL131C FKH1 forkhead protein, involved in transcriptional silencing, cell morphology and cell cycle YIR017C MET28 transcriptional activator of sulfur amino acid metabolism YIR018W YAP5 involved in transcription activation YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YJL006C CTK2 carboxy-terminal domain (CTD) kinase, beta subunit YJL056C ZAP1 metalloregulatory protein involved in zinc-responsive transcriptional regulation YJL089W SIP4 interacts with SNF1 protein kinase YJL103C YJL103C similarity to YBR239c YJL110C GZF3 transcriptional repressor YJL115W ASF1 anti-silencing protein YJL127C SPT10 transcription regulatory protein YJL164C TPK1 cAMP-dependent protein kinase 1, catalytic chain YJL176C SWI3 transcription regulatory protein YJL206C YJL206C similarity to YIL130p and PUT3P YJR032W CPR7 member of the cyclophilin family YJR060W CBF1 kinetochore protein YJR094C IME1 transcription factor required for sporulation YJR119C YJR119C similarity to human retinoblastoma binding protein 2 YJR122W CAF17 CCR4 associated factor YJR140C HIR3 involved in cell cycle regulation of histone transcription YJR147W HMS2 High-copy MEP2 Suppressor YKL015W PUT3 positive activator of the proline utilisation pathway YKL032C IXR1 intrastrand crosslink recognition protein and transcription factor YKL038W RGT1 regulator of glucose-induced genes YKL043W PHD1 transcription factor YKL062W MSN4 transcriptional activator YKL070W YKL070W similarity to B.subtilis transcriptional regulatory protein YKL072W STB6 SIN3 binding protein YKL093W MBR1 required for optimal growth on glycerol YKL109W HAP4 CCAAT-binding factor subunit YKL112W ABF1 ARS-binding factor YKL139W CTK1 carboxy-terminal domain (CTD) kinase, alpha subunit YKL159C RCN1 inhibitor of calcineurin YKL166C TPK3 cAMP-dependent protein kinase 3, catalytic chain YKL185W ASH1 negative regulator of HO transcription YKL190W CNB1 calcineurin B, regulatory subunit YKL222C YKL222C weak similarity to transcription factors, similarity to finger proteins YOR162c, YOR172w and YLR266c YKR034W DAL80 transcriptional repressor for allantoin and GABA catabolic genes YKR036C CAF4 CCR4 associated factor YKR064W YKR064W weak similarity to transcription factors YKR072C SIS2 involved in cell cycle-specific gene expression YKR099W BAS1 transcription factor YKR101W SIR1 silencing regulatory protein YLL004W ORC3 origin recognition complex, 62 kDa subunit YLL054C YLL054C similarity to transcription factor PIP2P YLR013W GAT3 weak similarity to nitrogen regulatory proteins YLR014C PPR1 transcription factor regulating pyrimidine pathway YLR039C RIC1 involved in transcription of ribosomal proteins and ribosomal RNA YLR055C SPT8 transcriptional adaptor or co-activator YLR098C CHA4 transcription factor YLR131C ACE2 metallothionein expression activator YLR176C RFX1 repressor of DNA damage-inducible genes YLR182W SWI6 transcription factor YLR192C HCR1 component of translation initiation factor eIF3, has similarity to human eIF3 p35 subunit YLR216C CPR6 member of the cyclophilin family YLR226W BUR2 divergent CDK-cyclin complex YLR228C ECM22 strong similarity to YDR213w, weak similarity to LYS14P YLR256W HAP1 transcription factor YLR266C YLR266C weak similarity to transcription factors YLR278C YLR278C weak similarity to regulatory proteins YLR321C SFH1 subunit of the RSC complex YLR399C BDF1 sporulation protein YLR418C CDC73 DNA-directed RNA polymerase II accessory protein YLR433C CNA1 calcineurin B, catalytic subunit YLR442C SIR3 silencing regulatory and DNA-repair protein YLR451W LEU3 transcription factor YML007W YAP1 transcriptional activator involved in oxidative stress response YML051W GAL80 negative regulator for expression of galactose-induced genes YML057W CMP2 calcineurin B, catalytic subunit YML065W ORC1 origin recognition complex, 104 KD subunit YML076C YML076C weak similarity to transcription factor YML081W YML081W strong similarity to ZMS1 protein YML099C ARG81 transcription factor involved in arginine metabolism YML112W CTK3 carboxy-terminal domain (CTD) kinase, gamma subunit YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR019W STB4 weak similarity to YIL130w, PUT3P and other transcription factors YMR021C MAC1 metal binding activator YMR037C MSN2 stress responsive regulatory protein YMR039C SUB1 transcriptional coactivator YMR042W ARG80 transcription factor involved in arginine metabolism YMR043W MCM1 transcription factor of the MADS box family YMR053C STB2 SIN3P binding protein YMR061W RNA14 component of pre-mRNA 3'-end processing factor CF I YMR070W MOT3 high-copy suppressor of MOT1-SPT3 synthetic lethality YMR127C SAS2 involved in silencing at HMR YMR139W RIM11 ser/thr protein kinase YMR179W SPT21 required for normal transcription at a number of loci YMR182C RGM1 transcriptional repressor protein YMR263W SAP30 subunit of the histone deacetylase B complex YMR280C CAT8 transcription factor involved in gluconeogenesis YNL012W SPO1 transcriptional regulator involved in sporulation YNL021W HDA1 histone deacetylase A YNL027W CRZ1 calcineurin responsive zinc-finger YNL030W HHF2 histone H4 YNL031C HHT2 histone H3 YNL076W MKS1 pleiotropic regulatory factor YNL097C PHO23 involved in transcriptional regulation of PHO5 YNL103W MET4 transcriptional activator of sulfur metabolism YNL107W YAF9 similarity to human AF-9 protein YNL167C SKO1 cre-binding bzip protein YNL186W UBP10 derepression of telomeric silencing YNL199C GCR2 glycolytic genes transcriptional activator YNL204C SPS18 sporulation-specific zinc-finger protein YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL222W SSU72 suppressor of cs mutant of SUA7 YNL236W SIN4 global regulator protein YNL251C NRD1 involved in regulation of nuclear pre-mRNA abundance YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL309W STB1 SIN3P binding protein YNL314W DAL82 transcriptional activator for allantoin catabolic genes YNL330C RPD3 histone deacetylase B YNR023W SNF12 component of SWI/SNF global transcription activator complex YNR052C POP2 required for glucose derepression YOL001W PHO80 cyclin YOL004W SIN3 transcription regulatory protein YOL028C YAP7 involved in transcription activation YOL055C THI20 hydroxymethylpyrimidine phosphate (HMP-P) kinase YOL067C RTG1 basic helix-loop-helix transcription factor that regulates CIT2 gene expression YOL068C HST1 silencing protein YOL089C HAL9 transcriptional activator of ENA1 YOL108C INO4 basic helix-loop-helix transcription factor YOL116W MSN1 transcriptional activator YOL133W HRT1 similarity to Lotus RING-finger protein YOL135C MED7 member of RNA Polymerase II transcriptional regulation mediator complex YOL148C SPT20 member of the TBP class of SPT proteins that alter transcription site selection YOR025W HST3 silencing protein YOR028C CIN5 transcriptional activator YOR038C HIR2 histone transcription regulator YOR047C STD1 dosage-dependent modulator of glucose repression YOR140W SFL1 transcription factor YOR213C SAS5 subunit of the RSC complex YOR259C RPT4 26S proteasome regulatory subunit YOR290C SNF2 component of SWI/SNF global transcription activator complex YOR298C-A MBF1 multiprotein bridging factor mediates GCN4-dependent transcriptional activation YOR304W ISW2 strong similarity to Drosophila ISW1 and human SNF2P homolog YOR337W TEA1 TY1 enhancer activator YOR344C TYE7 basic helix-loop-helix transcription factor YOR358W HAP5 CCAAT-binding factor subunit YOR363C PIP2 peroxisome proliferating transcription factor YPL015C HST2 similarity to HST1P and SIR2P YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL031C PHO85 cyclin-dependent protein kinase YPL037C EGD1 GAL4 DNA-binding enhancer protein YPL038W MET31 transcriptional regulator of sulfur amino acid metabolism YPL042C SSN3 cyclin-dependent CTD kinase YPL075W GCR1 transcriptional activator YPL082C MOT1 transcriptional accessory protein YPL089C RLM1 transcription factor of the MADS box family YPL139C UME1 negative regulator of meiosis YPL177C CUP9 involved in copper homeostasis repression of protein import YPL203W TPK2 cAMP-dependent protein kinase 2, catalytic chain YPL248C GAL4 transcription factor YPL254W HFI1 transcriptional coactivator YPR065W ROX1 heme-dependent transcriptional repressor of hypoxic genes YPR072W NOT5 component of the NOT protein complex YPR104C FHL1 transcriptional activator of the forkhead/hnf3 family YPR115W YPR115W similarity to probable transcription factor ASK10P, and to YNL047c and YIL105c YPR162C ORC4 origin recognition complex, 56 KD subunit YPR168W NUT2 negative transcription regulator from artifical reporters YPR196W YPR196W strong similarity to regulatory protein Mal63p mRNA processing (splicing, 5'-, 3'-end processing) (142 ORFs) 04.05.05 142 YAL032C PRP45 pre-mRNA splicing factor YAL043C PTA1 pre-tRNA processing protein / PF I subunit YBL022C PIM1 ATP-dependent protease, mitochondrial YBL026W LSM2 Sm-like (Lsm) protein YBL074C AAR2 A1 cistron splicing factor YBR055C PRP6 snRNP(U4/U6)-associated splicing factor YBR119W MUD1 U1 snRNP-specific A protein YBR120C CBP6 apo-cytochrome B pre-mRNA processing protein YBR142W MAK5 ATP-dependent RNA helicase YBR152W SPP381 Suppressor of Pre-mRNA Processing mutant YBR188C NTC20 splicing factor YBR236C ABD1 mRNA cap methyltransferase YBR237W PRP5 pre-mRNA processing RNA-helicase YCR077C PAT1 topoisomerase II-associated protein YDL030W PRP9 pre-mRNA splicing factor (snRNA-associated protein) YDL043C PRP11 pre-mRNA splicing factor YDL044C MTF2 mitochondrial protein involved in mRNA splicing and protein synthesis YDL084W SUB2 probably involved in pre-mRNA splicing YDL087C LUC7 yeast U1 snRNP protein with a role in 5' splice site recognition YDL098C SNU23 Putative RNA binding zinc finger protein YDR028C REG1 regulatory subunit for protein phosphatase GLC7P YDR088C SLU7 pre-mRNA splicing factor affecting 3' splice site choice YDR194C MSS116 RNA helicase of the DEAD box family, mitochondrial YDR195W REF2 RNA 3'-end formation protein YDR228C PCF11 component of pre-mRNA 3'-end processing factor CF I YDR235W PRP42 U1 snRNP associated protein, required for pre-mRNA splicing YDR240C SNU56 U1 snRNA protein, no counterpart in mammalian snRNP YDR243C PRP28 pre-mRNA splicing factor RNA helicase of DEAD box family YDR301W CFT1 pre-mRNA 3'-end processing factor CF II YDR378C LSM6 Sm-like (Lsm) protein YDR390C UBA2 E1-like (ubiquitin-activating) enzyme YDR416W SYF1 synthetic lethal with CDC40 YDR473C PRP3 essential splicing factor YEL026W SNU13 component of the U4/U6.U5 snRNP YER013W PRP22 pre-mRNA splicing factor YER029C SMB1 associated with U1 snRNP as part of the Sm-core that is common to all spliceosomal snRNPs YER032W FIR1 interacts with the poly(A) polymerase in the two hybrid system YER112W LSM4 Sm-like (Lsm) protein YER146W LSM5 Sm-like (Lsm) protein YER165W PAB1 mRNA polyadenylate-binding protein YER172C BRR2 RNA helicase-related protein YFR005C SAD1 SnRNP assembly defective YGL044C RNA15 component of pre-mRNA 3'-end processing factor CF I YGL094C PAN2 component of PAB1P-stimulated poly(A) ribonuclease YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL120C PRP43 involved in spliceosome disassembly YGL122C NAB2 nuclear poly(A)-binding protein YGL130W CEG1 mRNA guanylyltransferase (mRNA capping enzyme, alpha subunit) YGL141W HUL5 ubiquitin-protein ligase (E3) YGL173C KEM1 multifunctional nuclease YGR006W PRP18 U5 snRNA-associated protein YGR013W SNU71 associated with U1 snRNP, no counterpart in mammalian U1 snRNP YGR074W SMD1 snRNA-associated protein YGR075C PRP38 pre-mRNA splicing factor YGR091W PRP31 pre-mRNA splicing protein YGR129W SYF2 synthetic lethal with CDC40 YGR158C MTR3 involved in mRNA transport YGR222W PET54 splicing protein and translational activator, mitochondrial YHL038C CBP2 apo-cytochrome b pre-mRNA processing protein 2 YHR015W MIP6 similarity to PES4 a PAB-like protein YHR086W NAM8 meiotic recombination protein YHR165C PRP8 U5 snRNP protein, pre-mRNA splicing factor YIL061C SNP1 U1 small nuclear ribonucleoprotein YIR009W MSL1 U2 snRNA-associated protein with similarity to U2B YIR021W MRS1 involved in mitochondrial RNA splicing of COB mRNA YJL124C LSM1 Sm-like (Lsm) protein YJL133W MRS3 RNA splicing protein and member of the mitochondrial carrier family (MCF) YJL203W PRP21 pre-mRNA splicing factor YJL209W CBP1 apo-cytochrome b pre-mRNA processing protein YJR017C ESS1 processing/termination factor 1 YJR022W LSM8 splicing factor YJR036C HUL4 hect domain E3 ubiquitin-protein ligase YJR050W ISY1 pre-mRNA splicing factor YJR093C FIP1 component of pre-mRNA polyadenylation factor PF I YKL009W MRT4 mRNA turnover 4 YKL012W PRP40 splicing factor YKL025C PAN3 component of the PAB1P-dependent poly(A) ribonuclease YKL074C MUD2 pre-mRNA splicing factor YKL078W DHR2 RNA helicase, involved in ribosomal RNA maturation YKL208W CBT1 apo-cytochrome b pre-mRNA processing protein YKR002W PAP1 poly(A) polymerase YKR052C MRS4 RNA splicing protein and member of the mitochondrial carrier family (MCF) YKR086W PRP16 RNA-dependent ATPase YLL036C PRP19 non-snRNP sliceosome component required for DNA repair YLR115W CFT2 cleavage and polyadenylation specificity factor, part of CF II YLR116W MSL5 branch point bridging protein YLR117C CLF1 strong similarity to Drosophila putative cell cycle control protein crn YLR147C SMD3 spliceosomal snRNA-associated Sm core protein required for pre-mRNA splicing YLR275W SMD2 U1 snRNP protein of the Sm class YLR277C YSH1 component of pre-mRNA polyadenylation factor PF I YLR298C YHC1 associated with the U1 snRNP complex YLR382C NAM2 leucine--tRNA ligase precursor, mitochondrial YLR438C-A LSM3 Sm-like (Lsm) protein YML046W PRP39 pre-mRNA splicing factor YML049C RSE1 involved in RNA splicing and ER to Golgi transport YMR023C MSS1 mitochondrial GTPase involved in expression of COX1 YMR061W RNA14 component of pre-mRNA 3'-end processing factor CF I YMR125W STO1 large subunit of the nuclear cap-binding protein complex CBC YMR180C CTL1 RNA 5'-triphosphatase with manganese- or cobalt-dependent NTPase activities YMR240C CUS1 U2 snRNP protein YMR268C PRP24 pre-mRNA splicing factor YMR287C MSU1 3'-5' exonuclease for RNA 3' ss-tail, mitochondrial YMR288W HSH155 component of a multiprotein splicing factor YNL147W LSM7 Sm-like (Lsm) protein YNL210W MER1 meiotic recombination protein YNL286W CUS2 cold sensitive U2 snRNA Suppressor YNL317W PFS2 polyadenylation factor I subunit 2 required for mRNA 3'-end processing, bridges two mRNA 3'-end processing factors YNR011C PRP2 RNA-dependent ATPase of DEAH box family YOL123W HRP1 CF Ib (RNA3' Cleavage factor Ib) YOL149W DCP1 mRNA decapping enzyme YOR148C SPP2 involved in pre-mRNA processing YOR159C SME1 spliceosomal snRNA-associated Sm core protein required for mRNA splicing, also likely associated with telomerase TLC1 RNA YOR179C YOR179C similarity to BRR5 protein YOR204W DED1 ATP-dependent RNA helicase YOR250C CLP1 cleavage/polyadenylation factor IA subunit YOR308C SNU66 component of U4/U6.U5 snRNP YOR319W HSH49 essential yeast splicing factor YOR334W MRS2 RNA splicing protein and member of the mitochondrial carrier family (MCF) YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL060W LPE10 strong similarity to MRS2P YPL119C DBP1 ATP-dependent RNA helicase YPL178W CBC2 small subunit of the nuclear cap-binding protein complex CBC YPL190C NAB3 polyadenylated RNA-binding protein YPL213W LEA1 U2 A' snRNP protein YPL228W CET1 RNA 5'-triphosphatase (mRNA capping enzyme, beta subunit) YPR057W BRR1 involved in snRNP biogenesis YPR101W SNT309 splicing factor YPR107C YTH1 protein of the 3' processing complex YPR125W MRS7 suppressor of MRS2-1 mutation YPR134W MSS18 splicing protein YPR178W PRP4 U4/U6 snRNP 52 KD protein YPR182W SMX3 snRNA-associated protein of the SM family Q0050 AI1 COX1 intron 1 protein Q0055 AI2 COX1 intron 2 protein Q0060 AI3 DNA endonuclease Q0065 AI4 DNA endonuclease Q0070 AI5_ALPHA DNA endonuclease AI5_ALPHA Q0110 BI2 mRNA maturase BI2 Q0115 BI3 mRNA maturase BI3 Q0120 BI4 mRNA maturase BI4 Q0160 SCEI DNA endonuclease in 21S rRNA intron Q0255 Q0255 similarity to Podospora cytb intron 1a and coII intron protein 2 splicing (101 ORFs) 04.05.05.01 101 YAL032C PRP45 pre-mRNA splicing factor YBL022C PIM1 ATP-dependent protease, mitochondrial YBL026W LSM2 Sm-like (Lsm) protein YBL074C AAR2 A1 cistron splicing factor YBR055C PRP6 snRNP(U4/U6)-associated splicing factor YBR119W MUD1 U1 snRNP-specific A protein YBR142W MAK5 ATP-dependent RNA helicase YBR152W SPP381 Suppressor of Pre-mRNA Processing mutant YBR188C NTC20 splicing factor YBR237W PRP5 pre-mRNA processing RNA-helicase YDL030W PRP9 pre-mRNA splicing factor (snRNA-associated protein) YDL043C PRP11 pre-mRNA splicing factor YDL044C MTF2 mitochondrial protein involved in mRNA splicing and protein synthesis YDL084W SUB2 probably involved in pre-mRNA splicing YDL087C LUC7 yeast U1 snRNP protein with a role in 5' splice site recognition YDL098C SNU23 Putative RNA binding zinc finger protein YDR028C REG1 regulatory subunit for protein phosphatase GLC7P YDR088C SLU7 pre-mRNA splicing factor affecting 3' splice site choice YDR194C MSS116 RNA helicase of the DEAD box family, mitochondrial YDR235W PRP42 U1 snRNP associated protein, required for pre-mRNA splicing YDR240C SNU56 U1 snRNA protein, no counterpart in mammalian snRNP YDR243C PRP28 pre-mRNA splicing factor RNA helicase of DEAD box family YDR378C LSM6 Sm-like (Lsm) protein YDR416W SYF1 synthetic lethal with CDC40 YDR473C PRP3 essential splicing factor YEL026W SNU13 component of the U4/U6.U5 snRNP YER013W PRP22 pre-mRNA splicing factor YER029C SMB1 associated with U1 snRNP as part of the Sm-core that is common to all spliceosomal snRNPs YER112W LSM4 Sm-like (Lsm) protein YER146W LSM5 Sm-like (Lsm) protein YER172C BRR2 RNA helicase-related protein YFR005C SAD1 SnRNP assembly defective YGL120C PRP43 involved in spliceosome disassembly YGR006W PRP18 U5 snRNA-associated protein YGR013W SNU71 associated with U1 snRNP, no counterpart in mammalian U1 snRNP YGR074W SMD1 snRNA-associated protein YGR075C PRP38 pre-mRNA splicing factor YGR091W PRP31 pre-mRNA splicing protein YGR129W SYF2 synthetic lethal with CDC40 YGR222W PET54 splicing protein and translational activator, mitochondrial YHL038C CBP2 apo-cytochrome b pre-mRNA processing protein 2 YHR086W NAM8 meiotic recombination protein YHR165C PRP8 U5 snRNP protein, pre-mRNA splicing factor YIL061C SNP1 U1 small nuclear ribonucleoprotein YIR009W MSL1 U2 snRNA-associated protein with similarity to U2B YIR021W MRS1 involved in mitochondrial RNA splicing of COB mRNA YJL133W MRS3 RNA splicing protein and member of the mitochondrial carrier family (MCF) YJL203W PRP21 pre-mRNA splicing factor YJR022W LSM8 splicing factor YJR050W ISY1 pre-mRNA splicing factor YKL012W PRP40 splicing factor YKL074C MUD2 pre-mRNA splicing factor YKL078W DHR2 RNA helicase, involved in ribosomal RNA maturation YKR052C MRS4 RNA splicing protein and member of the mitochondrial carrier family (MCF) YKR086W PRP16 RNA-dependent ATPase YLL036C PRP19 non-snRNP sliceosome component required for DNA repair YLR116W MSL5 branch point bridging protein YLR117C CLF1 strong similarity to Drosophila putative cell cycle control protein crn YLR147C SMD3 spliceosomal snRNA-associated Sm core protein required for pre-mRNA splicing YLR275W SMD2 U1 snRNP protein of the Sm class YLR298C YHC1 associated with the U1 snRNP complex YLR382C NAM2 leucine--tRNA ligase precursor, mitochondrial YLR438C-A LSM3 Sm-like (Lsm) protein YML046W PRP39 pre-mRNA splicing factor YML049C RSE1 involved in RNA splicing and ER to Golgi transport YMR023C MSS1 mitochondrial GTPase involved in expression of COX1 YMR125W STO1 large subunit of the nuclear cap-binding protein complex CBC YMR240C CUS1 U2 snRNP protein YMR268C PRP24 pre-mRNA splicing factor YMR287C MSU1 3'-5' exonuclease for RNA 3' ss-tail, mitochondrial YMR288W HSH155 component of a multiprotein splicing factor YNL147W LSM7 Sm-like (Lsm) protein YNL210W MER1 meiotic recombination protein YNL286W CUS2 cold sensitive U2 snRNA Suppressor YNR011C PRP2 RNA-dependent ATPase of DEAH box family YOR148C SPP2 involved in pre-mRNA processing YOR159C SME1 spliceosomal snRNA-associated Sm core protein required for mRNA splicing, also likely associated with telomerase TLC1 RNA YOR204W DED1 ATP-dependent RNA helicase YOR308C SNU66 component of U4/U6.U5 snRNP YOR319W HSH49 essential yeast splicing factor YOR334W MRS2 RNA splicing protein and member of the mitochondrial carrier family (MCF) YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL060W LPE10 strong similarity to MRS2P YPL119C DBP1 ATP-dependent RNA helicase YPL213W LEA1 U2 A' snRNP protein YPR057W BRR1 involved in snRNP biogenesis YPR101W SNT309 splicing factor YPR125W MRS7 suppressor of MRS2-1 mutation YPR134W MSS18 splicing protein YPR178W PRP4 U4/U6 snRNP 52 KD protein YPR182W SMX3 snRNA-associated protein of the SM family Q0050 AI1 COX1 intron 1 protein Q0055 AI2 COX1 intron 2 protein Q0060 AI3 DNA endonuclease Q0065 AI4 DNA endonuclease Q0070 AI5_ALPHA DNA endonuclease AI5_ALPHA Q0110 BI2 mRNA maturase BI2 Q0115 BI3 mRNA maturase BI3 Q0120 BI4 mRNA maturase BI4 Q0160 SCEI DNA endonuclease in 21S rRNA intron Q0255 Q0255 similarity to Podospora cytb intron 1a and coII intron protein 2 3'-end processing (2 ORFs) 04.05.05.05 2 YKL208W CBT1 apo-cytochrome b pre-mRNA processing protein YNL317W PFS2 polyadenylation factor I subunit 2 required for mRNA 3'-end processing, bridges two mRNA 3'-end processing factors other mRNA-transcription activities (9 ORFs) 04.05.99 9 YER028C YER028C similarity to MIG1P YFL017W-A SMX2 snRNP G protein (the homologue of the human Sm-G) YIR001C SGN1 similarity to D.melanogaster RNA binding protein YJR127C ZMS1 transcription factor with similarity to regulatory protein ARD1P YNL016W PUB1 major polyadenylated RNA-binding protein of nucleus and cytoplasm YOL042W NGL1 similarity to CCR4 protein YOL123W HRP1 CF Ib (RNA3' Cleavage factor Ib) YPR068C HOS1 similarity to human histone deacetylase HD1 YPR137W RRP9 protein associated with the U3 small nucleolar RNA, required for pre-ribosomal RNA processing RNA transport (27 ORFs) 04.07 27 YDL207W GLE1 RNA export mediator YDR002W YRB1 ran-specific GTPase-activating protein YDR192C NUP42 nuclear pore protein YDR395W SXM1 putative beta-karyopherin YDR432W NPL3 nucleolar protein YER107C GLE2 required for nuclear pore complex structure and function YGL092W NUP145 nuclear pore protein YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL122C NAB2 nuclear poly(A)-binding protein YGL172W NUP49 nuclear pore protein YGR158C MTR3 involved in mRNA transport YGR218W CRM1 nuclear export factor, exportin YIR011C STS1 required for transport of RNA15P from the cytoplasm to the nucleus YJL050W MTR4 involved in nucleocytoplasmic transport of mRNA YJL061W NUP82 nuclear pore protein YKL057C NUP120 nuclear pore protein YKL068W NUP100 nuclear pore protein YKL186C MTR2 mRNA transport protein YKL205W LOS1 pre-tRNA splicing protein YKR082W NUP133 nuclear pore protein YLR119W SRN2 suppressor of RNA1-1 mutation YLR293C GSP1 GTP-binding protein of the ras superfamily YMR235C RNA1 GTPase activating protein YOL123W HRP1 CF Ib (RNA3' Cleavage factor Ib) YOR160W MTR10 involved in nuclear protein import YOR185C GSP2 GTP-binding protein of the RAS superfamily YPL169C MEX67 factor for nuclear mRNA export other transcription activities (57 ORFs) 04.99 57 YAL016W TPD3 ser/thr protein phosphatase 2A, regulatory chain A YBR150C TBS1 weak similarity to transcription factors YBR212W NGR1 glucose-repressible RNA-binding protein YBR233W PBP2 PAB1 binding protein YBR239C YBR239C weak similarity to transcription factor PUT3P YCL033C YCL033C similarity to M.capricolum transcription repressor YCL037C SRO9 La motif-containing proteins that modulate mRNA translation YCR004C YCP4 strong similarity to S. pombe protein obr1 YCR087C-A YCR087C-A similarity to S. pombe SPBC215.06c putative nucleic acid-binding protein YDL031W DBP10 putative RNA helicase involved in ribosome biogenesis YDL051W LHP1 RNA binding protein YDL160C DHH1 putative RNA helicase of the DEAD box family YDR451C YHP1 strong similarity to YOX1P YER116C SLX8 subunit of HEX3P-SLX8P complex, required for cell growth in the absence of SGS1 or TOP3 YER129W PAK1 DNA polymerase alpha suppressing protein kinase YFL033C RIM15 protein kinase involved in expression of meiotic genes YGL014W PUF4 similarity to Drosophila pumilio protein and MPT5P protein YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL127C SOH1 allows HPR1 null mutant to grow at 37 deg. YGL251C HFM1 DNA/RNA helicase YGR067C YGR067C weak similarity to transcription factors YHR169W DBP8 strong similarity to DRS1P and other probable ATP-dependent RNA helicases YHR170W NMD3 nonsense-mediated mRNA decay protein YIL030C SSM4 involved in mRNA turnover YIL105C YIL105C weak similarity to probable transcription factor ASK10P YIR005W IST3 similarity to RNA-binding proteins YJL168C SET2 enhancer of zeste-like YKL005C YKL005C weak similarity to YKR029c and D.melanogaster transcription elongation factor DmS-II YKR092C SRP40 suppressor of mutant AC40 of RNA polymerase I and III YLR067C PET309 required for stability and translation of COX1 mRNA YLR139C SLS1 suppresses lethality of SSM4 deletion YLR147C SMD3 spliceosomal snRNA-associated Sm core protein required for pre-mRNA splicing YML017W PSP2 suppressor of DNA polymerase alpha mutation YML027W YOX1 homoeodomain protein YMR064W AEP1 nuclear control of ATPase messenger RNA expression protein YMR164C MSS11 activator of STA1, STA2, and STA3 YMR219W ESC1 Establishes Silent Chromatin YNL004W HRB1 strong similarity to GBP2P YNL037C IDH1 isocitrate dehydrogenase (NAD+) subunit 1, mitochondrial YNL068C FKH2 homology to D.melanogaster forkhead protein YNL175C NOP13 similarity to S.pombe Rnp24p, NSR1P and human splicing factor YNL255C GIS2 strong similarity to nucleic acid-binding proteins, similarity to Tetrahymena thermophila cnjB protein YNR063W YNR063W weak similarity to CYC1/CYP3 transcription activator YOL006C TOP1 DNA topoisomerase I YOL010W RCL1 similarity to human RNA 3'-terminal phosphate cyclase YOR113W AZF1 asparagine-rich zinc finger protein YOR136W IDH2 isocitrate dehydrogenase (NAD+) subunit 2, mitochondrial YOR229W WTM2 transcriptional modulator YOR230W WTM1 transcriptional modulator YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL133C YPL133C weak similarity to transcription factors YPL230W USV1 similarity to RGM1P, weak similarity to transcription factors YPR008W HAA1 similarity to transcription factor YPR013C YPR013C similarity to transcription factors YPR015C YPR015C similarity to transcription factors YPR031W YPR031W similarity to human zinc-finger protein BR140 YPR199C ARR1 involved in resistance to arsenic compounds PROTEIN SYNTHESIS (359 ORFs) 05 359 YAL003W EFB1 translation elongation factor eEF1beta YAL035W FUN12 general translation factor eIF2 homolog YBL027W RPL19B 60S large subunit ribosomal protein L19.e YBL038W MRPL16 ribosomal protein of the large subunit, mitochondrial YBL058W SHP1 potential regulatory subunit for GLC7P YBL072C RPS8A ribosomal protein S8.e YBL076C ILS1 isoleucyl-tRNA synthetase YBL080C PET112 required to maintain rho+ mitochondrial DNA YBL087C RPL23A 60S large subunit ribosomal protein L23.e YBL090W MRP21 Mitochondrial ribosomal protein YBL091C MAP2 methionine aminopeptidase, isoform 2 YBL092W RPL32 60S large subunit ribosomal protein L32.e YBR024W SCO2 involved in stability of COX1P and COX2P YBR031W RPL4A ribosomal protein YBR048W RPS11B ribosomal protein S11.e.B YBR079C RPG1 translation initiation factor eIF3 (p110 subunit) YBR084C-A RPL19A 60S large subunit ribosomal protein L19.e YBR118W TEF2 translation elongation factor eEF1 alpha-A chain, cytosolic YBR120C CBP6 apo-cytochrome B pre-mRNA processing protein YBR121C GRS1 glycine--tRNA ligase YBR122C MRPL36 ribosomal protein YmL36 precursor, mitochondrial YBR143C SUP45 translational release factor YBR146W MRPS9 ribosomal protein S9 precursor, mitochondrial YBR181C RPS6B ribosomal protein S6.e YBR189W RPS9B ribosomal protein S9.e.B YBR191W RPL21A ribosomal protein L21.e YBR251W MRPS5 ribosomal protein S5, mitochondrial YBR268W MRPL37 ribosomal protein YmL37, mitochondrial YBR282W MRPL27 ribosomal protein YmL27 precursor, mitochondrial YCL031C RRP7 involved in pre-rRNA processing and ribosome assembly YCL054W SPB1 required for ribosome synthesis, putative methylase YCR003W MRPL32 ribosomal protein YmL32, mitochondrial YCR024C YCR024C asn-tRNA synthetase, mitochondrial YCR031C RPS14A 40S Ribosomal protein S14.e YCR046C IMG1 ribosomal protein, mitochondrial YDL040C NAT1 protein N-acetyltransferase subunit YDL044C MTF2 mitochondrial protein involved in mRNA splicing and protein synthesis YDL045W-A MRP10 mitochondrial ribosomal protein YDL061C RPS29B ribosomal protein S29.e.B YDL069C CBS1 translational activator of COB mRNA YDL075W RPL31A 60S large subunit ribosomal protein L31.e YDL081C RPP1A 60S large subunit acidic ribosomal protein a1 YDL082W RPL13A 60S large subunit ribosomal protein L13 YDL083C RPS16B ribosomal protein S16.e YDL130W RPP1B 60S large subunit acidic ribosomal protein L44prime YDL133C-A RPL41B ribosomal protein YDL136W RPL35B 60S large subunit ribosomal protein YDL148C NOP14 nuclear and nucleolar protein with possible role in ribosome biogenesis YDL184C RPL41A ribosomal protein YDL191W RPL35A 60S large subunit ribosomal protein YDL202W MRPL11 ribosomal protein of the large subunit, mitochondrial YDL229W SSB1 heat shock protein of HSP70 family YDR012W RPL4B ribosomal protein L4.e.B YDR023W SES1 seryl-tRNA synthetase, cytosolic YDR025W RPS11A ribosomal protein S11.e YDR037W KRS1 lysyl-tRNA synthetase, cytosolic YDR041W RSM10 component of the mitochondrial ribosomal small subunit YDR060W MAK21 protein required for 60S ribosomal subunit biogenesis YDR064W RPS13 ribosomal protein YDR115W YDR115W similarity to bacterial ribosomal L34 proteins YDR116C YDR116C similarity to bacterial ribosomal L1 proteins YDR172W SUP35 eukaryotic peptide chain release factor GTP-binding subunit YDR175C RSM24 component of the mitochondrial ribosomal small subunit YDR185C YDR185C strong similarity to MSF1P YDR197W CBS2 cytochrome B translational activator protein YDR211W GCD6 translation initiation factor eIF2b epsilon, 81 kDa subunit YDR237W MRPL7 ribosomal protein of the large subunit, mitochondrial YDR268W MSW1 tryptophanyl-tRNA synthetase, mitochondrial YDR283C GCN2 ser/thr protein kinase YDR322W MRPL35 ribosomal protein YmL35 of the large subunit, mitochondrial YDR337W MRPS28 ribosomal protein of the small subunit, mitochondrial YDR341C YDR341C arginyl-tRNA synthetase, cytosolic YDR347W MRP1 ribosomal protein of the small subunit, mitochondrial YDR382W RPP2B 60S large subunit acidic ribosomal protein YDR385W EFT2 translation elongation factor eEF2 YDR405W MRP20 ribosomal protein of the large subunit, mitochondrial YDR418W RPL12B 60S large subunit ribosomal protein L12.e YDR429C TIF35 translation initiation factor eIF3 (p33 subunit) YDR447C RPS17B ribosomal protein S17.e.B YDR450W RPS18A ribosomal protein S18.e.c4 YDR462W MRPL28 ribosomal protein of the large subunit (YmL28), mitochondrial YDR471W RPL27B 60S large subunit ribosomal protein YDR500C RPL37B ribosomal protein L.37.e YDR515W SLF1 La motif-containing proteins that modulate mRNA translation YEL034W HYP2 translation initiation factor eIF5A.1 YEL050C RML2 ribosomal L2 protein, mitochondrial YEL054C RPL12A 60S large subunit ribosomal protein L12.e YER025W GCD11 translation initiation factor eIF2 gamma chain YER050C RSM18 component of the mitochondrial ribosomal small subunit YER056C-A RPL34A ribosomal protein L34 YER074W RPS24A 40s small subunit ribosomal protein S24.e YER087W YER087W similarity to E.coli prolyl-tRNA synthetase YER102W RPS8B ribosomal protein S8.e YER117W RPL23B ribosomal protein L23.e YER131W RPS26B 40S small subunit ribosomal protein S26e-c5 YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER153C PET122 translational activator of cytochrome c oxidase subunit III YER165W PAB1 mRNA polyadenylate-binding protein YFL022C FRS2 phenylalanine--tRNA ligase beta chain, cytosolic YFL034C-A RPL22B ribosomal protein YFR009W GCN20 positive effector of GCN2P YFR031C-A RPL2A ribosomal protein L8.e YFR032C-A RPL29 60S large subunit ribosomal protein YFR049W YMR31 ribosomal protein, mitochondrial YGL030W RPL30 60S large subunit ribosomal protein L30.e YGL031C RPL24A 60S large subunit ribosomal protein L24.e.A YGL049C TIF4632 mRNA cap-binding protein (eIF4F), 130K subunit YGL068W YGL068W strong similarity to Cricetus mitochrondial ribosomal L12 protein YGL076C RPL7A 60S large subunit ribosomal protein L7.e.A YGL094C PAN2 component of PAB1P-stimulated poly(A) ribonuclease YGL103W RPL28 60S large subunit ribosomal protein L27a.e YGL123W RPS2 40S small subunit ribosomal protein YGL125W MET13 putative methylene tetrahydrofolate reductase YGL135W RPL1B 60S large subunit ribosomal protein YGL143C MRF1 peptide chain release factor, mitochondrial YGL147C RPL9A ribosomal protein L9.e YGL169W SUA5 translation initiation protein YGL189C RPS26A 40S small subunit ribosomal protein S26e.c7 YGL195W GCN1 translational activator YGL236C MTO1 strong similarity to gidA E.coli protein YGL245W YGL245W strong similarity to glutamine--tRNA ligase YGR027C RPS25A ribosomal protein S25.e.c7 YGR034W RPL26B 60S large subunit ribosomal protein YGR072W UPF3 nonsense-mediated mRNA decay protein YGR076C MRPL25 ribosomal protein YmL25, mitochondrial YGR083C GCD2 translation initiation factor eIF2B, 71 kDa (delta) subunit YGR084C MRP13 ribosomal protein of the small subunit, mitochondrial YGR085C RPL11B ribosomal protein YGR094W VAS1 valyl-tRNA synthetase YGR118W RPS23A 40S small subunit ribosomal protein S23.e YGR147C NAT2 N-acetyltransferase for N-terminal methionine YGR148C RPL24B 60S large subunit ribosomal protein L24.e.B YGR162W TIF4631 mRNA cap-binding protein (eIF4F), 150K subunit YGR171C MSM1 methionyl-tRNA synthetase YGR185C TYS1 tyrosyl-tRNA synthetase YGR201C YGR201C strong similarity to translation elongation factor eEF1 alpha chain CAM1P YGR214W RPS0A 40S ribosomal protein p40 homolog A YGR220C MRPL9 ribosomal protein YmL9, mitochondrial YGR222W PET54 splicing protein and translational activator, mitochondrial YGR264C MES1 methionyl-tRNA synthetase YHL001W RPL14B ribosomal protein YHL004W MRP4 ribosomal protein of the small subunit, mitochondrial YHL015W RPS20 ribosomal protein YHL033C RPL8A 60S large subunit ribosomal protein L7a.e.A YHR010W RPL27A 60S large subunit ribosomal protein L27.e YHR011W DIA4 strong similarity to seryl-tRNA synthetases YHR015W MIP6 similarity to PES4 a PAB-like protein YHR019C DED81 asparaginyl-tRNA-synthetase YHR020W YHR020W strong similarity to human glutamyl-prolyl-tRNA synthetase and fruit fly multifunctional aminoacyl-tRNA synthetase YHR021C RPS27B ribosomal protein S27.e YHR038W FIL1 Killed in Mutagen, sensitive to Diepoxybutane and/or Mitomycin C YHR075C PPE1 ribosomal protein of the small subunit, mitochondrial YHR077C NMD2 nonsense-mediated mRNA decay protein 2 YHR091C MSR1 arginyl-tRNA synthetase, mitochondrial YHR141C RPL42B ribosomal protein L36a.e YHR147C MRPL6 ribosomal protein of the large subunit, mitochondrial YHR189W YHR189W similarity to peptidyl-tRNA hydrolases YHR203C RPS4B ribosomal protein S4.e.c8 YIL018W RPL2B 60S large subunit ribosomal protein L8.e YIL052C RPL34B ribosomal protein L34.e YIL069C RPS24B 40S small subunit ribosomal protein S24.e YIL078W THS1 threonyl tRNA synthetase, cytosolic YIL133C RPL16A 60S large subunit ribosomal protein YIL148W RPL40A ubiquitin YJL023C PET130 protein synthesis protein, mitochondrial YJL063C MRPL8 ribosomal protein L17, mitochondrial YJL096W MRPL49 ribosomal protein YmL49, mitochondrial YJL102W MEF2 translation elongation factor, mitochondrial YJL125C GCD14 translational repressor of GCN4 YJL136C RPS21B 40S small subunit ribosomal protein S21.e YJL138C TIF2 translation initiation factor eIF4A YJL177W RPL17B 60s large subunit ribosomal protein L17.e YJL189W RPL39 60S large subunit ribosomal protein L39.e YJL190C RPS22A ribosomal protein S15a.e.c10 YJL191W RPS14B 40S small subunit ribosomal protein S14.e.B YJR007W SUI2 translation initiation factor eIF2, alpha chain YJR047C ANB1 translation initiation factor eIF5A.2 YJR066W TOR1 phosphatidylinositol 3-kinase YJR094W-A RPL43B 60S large subunit ribosomal protein YJR113C RSM7 similarity to bacterial, chloroplast and mitochondrial ribosomal protein S7 YJR123W RPS5 ribosomal protein S5.e YJR145C RPS4A ribosomal protein S4.e.c10 YKL003C MRP17 ribosomal protein of the small subunit, mitochondrial YKL006W RPL14A ribosomal protein YKL009W MRT4 mRNA turnover 4 YKL056C YKL056C strong similarity to human IgE-dependent histamine-releasing factor YKL081W TEF4 translation elongation factor eEF1, gamma chain YKL138C MRPL31 ribosomal protein YmL31, mitochondrial YKL142W MRP8 ribosomal protein, mitochondrial YKL156W RPS27A ribosomal protein S27.e YKL167C MRP49 ribosomal protein, mitochondrial YKL170W MRPL38 ribosomal protein of the large subunit (L14), mitochondrial YKL173W SNU114 U5 snRNP-specific protein YKL180W RPL17A ribosomal protein L17.e YKL194C MST1 threonine--tRNA ligase, mitochondrial YKL204W EAP1 translation initiation factor 4E-associated protein YKR006C MRPL13 ribosomal protein YmL13, mitochondrial YKR026C GCN3 translation initiation factor eIF2B, 34 KD, alpha subunit YKR057W RPS21A ribosomal protein S21.e YKR059W TIF1 translation initiation factor 4A YKR084C HBS1 translation elongation factor eEF-1 alpha chain homolog YKR085C MRPL20 ribosomal protein YmL20, mitochondrial YKR094C RPL40B ubiquitin YLL018C DPS1 aspartyl-tRNA synthetase, cytosolic YLL039C UBI4 ubiquitin YLL045C RPL8B 60s large subunit ribosomal protein L7a.e.B YLR005W SSL1 TFIIH subunit (transcription initiation factor), factor B YLR009W YLR009W similarity to ribosomal protein L24.e.B YLR029C RPL15A 60s large subunit ribosomal protein L15.e.c12 YLR048W RPS0B 40S ribosomal protein p40 homolog B YLR060W FRS1 phenylalanyl-tRNA synthetase, alpha subunit, cytosolic YLR061W RPL22A ribosomal protein YLR067C PET309 required for stability and translation of COX1 mRNA YLR069C MEF1 translation elongation factor G, mitochondrial YLR075W RPL10 60S large subunit ribosomal protein YLR167W RPS31 ubiquitin/40S small subunit ribosomal protein YLR185W RPL37A ribosomal protein L37.e YLR203C MSS51 possibly involved in translational activation of COX1 and COB mRNA YLR249W YEF3 translation elongation factor eEF3 YLR264W RPS28B 40S small subunit ribosomal protein S28.e.c12 YLR287C-A RPS30A 40S small subunit ribosomal protein YLR289W GUF1 strong similarity to E. coli elongation factor-type GTP-binding protein lepa YLR291C GCD7 translation initiation factor eIF2b, 43 kDa subunit YLR312W-A MRPL15 ribosomal protein of the large subunit, mitochondrial YLR325C RPL38 60S large subunit ribosomal protein YLR333C RPS25B ribosomal protein S25.e.c12 YLR340W RPP0 acidic ribosomal protein L10.e YLR344W RPL26A 60S large subunit ribosomal protein YLR367W RPS22B ribosomal protein S15a.e.c12 YLR382C NAM2 leucine--tRNA ligase precursor, mitochondrial YLR388W RPS29A ribosomal protein S29.e.A YLR406C RPL31B 60S large subunit ribosomal protein L31.e.c12 YLR439W MRPL4 ribosomal protein, mitochondrial YLR441C RPS1A ribosomal protein S3a.e YLR448W RPL6B 60S large subunit ribosomal protein YML009C MRPL39 60S ribosomal protein, mitochondrial YML024W RPS17A ribosomal protein S17.e.A YML025C YML6 ribosomal protein, mitochondrial YML026C RPS18B ribosomal protein S18.e.c13 YML063W RPS1B ribosomal protein S3a.e YML073C RPL6A 60S large subunit ribosomal protein YMR005W MPT1 required for protein synthesis YMR012W CLU1 translation initiation factor eIF3 (p135 subunit) YMR023C MSS1 mitochondrial GTPase involved in expression of COX1 YMR024W MRPL3 ribosomal protein of the large subunit, mitochondrial YMR028W TAP42 component of the Tor signaling pathway YMR064W AEP1 nuclear control of ATPase messenger RNA expression protein YMR080C NAM7 nonsense-mediated mRNA decay protein YMR116C ASC1 40S small subunit ribosomal protein YMR121C RPL15B 60S large subunit ribosomal protein L15.e.c13 YMR142C RPL13B 60S large subunit ribosomal protein YMR143W RPS16A ribosomal protein S16.e YMR146C TIF34 translation initiation factor eIF3, p39 subunit YMR188C YMR188C weak similarity to bacterial ribosomal protein S17 YMR193W MRPL24 ribosomal protein of the large subunit, mitochondrial YMR194W RPL36A 60S large subunit ribosomal protein YMR225C MRPL44 ribosomal protein YMR44, mitochondrial YMR230W RPS10B ribosomal protein YMR242C RPL20A 60s large subunit ribosomal protein YMR257C PET111 required for translation of COX2 mRNA YMR260C TIF11 translation initiation factor eIF1a YMR282C AEP2 required for the expression of subunit-9 of atp synthase YMR286W MRPL33 ribosomal protein of the large subunit, mitochondrial YMR309C NIP1 associated with 40s ribosomal subunit YNL001W DOM34 functions in protein translation to promote G1 progression and differentiation YNL005C MRP7 ribosomal protein YmL2 precursor, mitochondrial YNL007C SIS1 heat shock protein YNL014W HEF3 translation elongation factor eEF3 homolog YNL053W MSG5 dual-specifity protein phosphatase YNL062C GCD10 translation initiation factor eIF3 RNA-binding subunit YNL067W RPL9B ribosomal protein L9.e.c14 YNL069C RPL16B 60S large subunit ribosomal protein YNL073W MSK1 lysyl-tRNA synthetase, mitochondrial YNL081C YNL081C similarity to ribosomal protein S13 YNL096C RPS7B strong similarity to ribosomal protein S7 YNL119W YNL119W weak similarity to M.jannaschii hypothetical protein MJ1257 YNL137C NAM9 ribosomal protein, mitochondrial YNL139C RLR1 regulatory protein YNL162W RPL42A ribosomal protein L36a.e YNL163C RIA1 translation elongation factor eEF4 YNL178W RPS3 ribosomal protein S3.e YNL185C MRPL19 ribosomal protein of the large subunit, mitochondrial YNL209W SSB2 heat shock protein of HSP70 family, cytosolic YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL217W YNL217W weak similarity to E.coli bis(5'-nucleosyl)-tetraphosphatase YNL244C SUI1 translation initiation factor 3 (eIF3) YNL247W YNL247W cysteinyl-tRNA synthetase YNL252C MRPL17 ribosomal protein of the large subunit (YmL30), mitochondrial YNL255C GIS2 strong similarity to nucleic acid-binding proteins, similarity to Tetrahymena thermophila cnjB protein YNL284C MRPL10 ribosomal protein of the large subunit, mitochondrial YNL301C RPL18B 60S large subunit ribosomal protein L18.e YNL302C RPS19B 40S small subunit ribosomal protein S19.e YNL306W MRPS18 ribosomal protein of the small subunit, mitochondrial YNR036C YNR036C strong similarity to ribosomal protein S12 YNR037C RSM19 strong similarity to Mycoplasma ribosomal protein S19 YNR045W PET494 translational activator, mitochondrial YOL023W IFM1 translation initiation factor 2, mitochondrial YOL033W MSE1 glutamyl-tRNA synthetase, mitochondrial YOL039W RPP2A acidic ribosomal protein P2.beta YOL040C RPS15 40S small subunit ribosomal protein YOL097C WRS1 tryptophan--tRNA ligase YOL120C RPL18A 60S large subunit ribosomal protein S18.e YOL121C RPS19A 40S small subunit ribosomal protein S19.e YOL127W RPL25 ribosomal protein L23a.e YOL139C CDC33 translation initiation factor eIF4E YOR017W PET127 component of mitochondrial translation system YOR063W RPL3 60S large subunit ribosomal protein L3.e YOR096W RPS7A ribosomal protein YOR133W EFT1 translation elongation factor eEF2 YOR150W MRPL23 ribosomal protein of the large subunit, mitochondrial YOR158W PET123 ribosomal protein, mitochondrial YOR167C RPS28A 40S small subunit ribosomal protein S28.e.c15 YOR168W GLN4 glutaminyl-tRNA synthetase YOR182C RPS30B ribosomal protein S30 YOR187W TUF1 translation elongation factor TU, mitochondrial YOR204W DED1 ATP-dependent RNA helicase YOR234C RPL33B ribosomal protein L35a.e.c15 YOR260W GCD1 translation initiation factor eIF2bgamma subunit YOR276W CAF20 mRNA CAP-binding protein (eIF4F), 20K subunit YOR293W RPS10A ribosomal protein S10.e YOR302W YOR302W CPA1 leader peptide YOR312C RPL20B 60S large subunit ribosomal protein YOR335C ALA1 alanyl-tRNA synthetase, cytosolic YOR361C PRT1 translation initiation factor eIF3 subunit YOR369C RPS12 40S small subunit acidic ribosomal protein S12 YPL013C YPL013C strong similarity to N.crassa mitochondrial ribosomal protein S24 YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL040C ISM1 isoleucine--tRNA ligase, mitochondrial YPL048W CAM1 translation elongation factor eEF1 gamma homologue YPL079W RPL21B ribosomal protein L21 YPL081W RPS9A ribosomal protein S9.e.A YPL090C RPS6A ribosomal protein S6.e YPL097W MSY1 tyrosyl-tRNA synthetase YPL104W MSD1 aspartate--tRNA ligase, mitochondrial YPL118W MRP51 mitochondrial ribosomal protein of the small subunit YPL131W RPL5 60S large subunit ribosomal protein L5.e YPL143W RPL33A ribosomal protein L35a.e.c16 YPL160W CDC60 leucine--tRNA ligase, cytosolic YPL173W MRPL40 ribosomal protein of the large subunit (YmL40), mitochondrial YPL179W PPQ1 phosphoprotein phosphatase YPL183W-A YPL183W-A strong similarity to mitochondrial and bacterial ribosomal L36 proteins YPL193W RSA1 nucleoplasmic protein involved in assembly of 60S ribosomal subunits YPL198W RPL7B 60S large subunit ribosomal protein YPL220W RPL1A ribosomal protein YPL226W NEW1 similarity to translation elongation factor eEF3 YPL237W SUI3 translation initiation factor eIF2 beta subunit YPL249C-A RPL36B 60S large subunit ribosomal protein YPR016C TIF6 translation initiation factor 6 (eIF6) YPR033C HTS1 histidine--tRNA ligase, mitochondrial YPR041W TIF5 translation initiation factor eIF5 YPR043W RPL43A ribosomal protein L37a.e YPR047W MSF1 phenylalanine--tRNA ligase alpha chain, mitochondrial YPR080W TEF1 translation elongation factor eEF1 alpha-A chain, cytosolic YPR081C YPR081C strong similarity to glycyl-tRNA synthetases YPR102C RPL11A ribosomal protein L11.e YPR132W RPS23B 40S small subunit ribosomal protein S23.e YPR163C TIF3 translation initiation factor eIF4B YPR166C MRP2 ribosomal protein S14 Q0140 VAR1 mitochondrial ribosomal protein ribosome biogenesis (215 ORFs) 05.01 215 YBL027W RPL19B 60S large subunit ribosomal protein L19.e YBL038W MRPL16 ribosomal protein of the large subunit, mitochondrial YBL072C RPS8A ribosomal protein S8.e YBL087C RPL23A 60S large subunit ribosomal protein L23.e YBL090W MRP21 Mitochondrial ribosomal protein YBL092W RPL32 60S large subunit ribosomal protein L32.e YBR031W RPL4A ribosomal protein YBR048W RPS11B ribosomal protein S11.e.B YBR084C-A RPL19A 60S large subunit ribosomal protein L19.e YBR122C MRPL36 ribosomal protein YmL36 precursor, mitochondrial YBR146W MRPS9 ribosomal protein S9 precursor, mitochondrial YBR181C RPS6B ribosomal protein S6.e YBR189W RPS9B ribosomal protein S9.e.B YBR191W RPL21A ribosomal protein L21.e YBR251W MRPS5 ribosomal protein S5, mitochondrial YBR268W MRPL37 ribosomal protein YmL37, mitochondrial YBR282W MRPL27 ribosomal protein YmL27 precursor, mitochondrial YCR003W MRPL32 ribosomal protein YmL32, mitochondrial YCR031C RPS14A 40S Ribosomal protein S14.e YCR046C IMG1 ribosomal protein, mitochondrial YDL045W-A MRP10 mitochondrial ribosomal protein YDL061C RPS29B ribosomal protein S29.e.B YDL075W RPL31A 60S large subunit ribosomal protein L31.e YDL081C RPP1A 60S large subunit acidic ribosomal protein a1 YDL082W RPL13A 60S large subunit ribosomal protein L13 YDL083C RPS16B ribosomal protein S16.e YDL130W RPP1B 60S large subunit acidic ribosomal protein L44prime YDL133C-A RPL41B ribosomal protein YDL136W RPL35B 60S large subunit ribosomal protein YDL148C NOP14 nuclear and nucleolar protein with possible role in ribosome biogenesis YDL184C RPL41A ribosomal protein YDL191W RPL35A 60S large subunit ribosomal protein YDL202W MRPL11 ribosomal protein of the large subunit, mitochondrial YDR012W RPL4B ribosomal protein L4.e.B YDR025W RPS11A ribosomal protein S11.e YDR041W RSM10 component of the mitochondrial ribosomal small subunit YDR064W RPS13 ribosomal protein YDR115W YDR115W similarity to bacterial ribosomal L34 proteins YDR116C YDR116C similarity to bacterial ribosomal L1 proteins YDR175C RSM24 component of the mitochondrial ribosomal small subunit YDR237W MRPL7 ribosomal protein of the large subunit, mitochondrial YDR322W MRPL35 ribosomal protein YmL35 of the large subunit, mitochondrial YDR337W MRPS28 ribosomal protein of the small subunit, mitochondrial YDR347W MRP1 ribosomal protein of the small subunit, mitochondrial YDR382W RPP2B 60S large subunit acidic ribosomal protein YDR405W MRP20 ribosomal protein of the large subunit, mitochondrial YDR418W RPL12B 60S large subunit ribosomal protein L12.e YDR447C RPS17B ribosomal protein S17.e.B YDR450W RPS18A ribosomal protein S18.e.c4 YDR462W MRPL28 ribosomal protein of the large subunit (YmL28), mitochondrial YDR471W RPL27B 60S large subunit ribosomal protein YDR500C RPL37B ribosomal protein L.37.e YEL050C RML2 ribosomal L2 protein, mitochondrial YEL054C RPL12A 60S large subunit ribosomal protein L12.e YER050C RSM18 component of the mitochondrial ribosomal small subunit YER056C-A RPL34A ribosomal protein L34 YER074W RPS24A 40s small subunit ribosomal protein S24.e YER102W RPS8B ribosomal protein S8.e YER117W RPL23B ribosomal protein L23.e YER131W RPS26B 40S small subunit ribosomal protein S26e-c5 YFL034C-A RPL22B ribosomal protein YFR031C-A RPL2A ribosomal protein L8.e YFR032C-A RPL29 60S large subunit ribosomal protein YFR049W YMR31 ribosomal protein, mitochondrial YGL030W RPL30 60S large subunit ribosomal protein L30.e YGL031C RPL24A 60S large subunit ribosomal protein L24.e.A YGL068W YGL068W strong similarity to Cricetus mitochrondial ribosomal L12 protein YGL076C RPL7A 60S large subunit ribosomal protein L7.e.A YGL103W RPL28 60S large subunit ribosomal protein L27a.e YGL123W RPS2 40S small subunit ribosomal protein YGL125W MET13 putative methylene tetrahydrofolate reductase YGL135W RPL1B 60S large subunit ribosomal protein YGL147C RPL9A ribosomal protein L9.e YGL189C RPS26A 40S small subunit ribosomal protein S26e.c7 YGR027C RPS25A ribosomal protein S25.e.c7 YGR034W RPL26B 60S large subunit ribosomal protein YGR076C MRPL25 ribosomal protein YmL25, mitochondrial YGR084C MRP13 ribosomal protein of the small subunit, mitochondrial YGR085C RPL11B ribosomal protein YGR118W RPS23A 40S small subunit ribosomal protein S23.e YGR148C RPL24B 60S large subunit ribosomal protein L24.e.B YGR214W RPS0A 40S ribosomal protein p40 homolog A YGR220C MRPL9 ribosomal protein YmL9, mitochondrial YHL001W RPL14B ribosomal protein YHL004W MRP4 ribosomal protein of the small subunit, mitochondrial YHL015W RPS20 ribosomal protein YHL033C RPL8A 60S large subunit ribosomal protein L7a.e.A YHR010W RPL27A 60S large subunit ribosomal protein L27.e YHR021C RPS27B ribosomal protein S27.e YHR075C PPE1 ribosomal protein of the small subunit, mitochondrial YHR141C RPL42B ribosomal protein L36a.e YHR147C MRPL6 ribosomal protein of the large subunit, mitochondrial YHR203C RPS4B ribosomal protein S4.e.c8 YIL018W RPL2B 60S large subunit ribosomal protein L8.e YIL052C RPL34B ribosomal protein L34.e YIL069C RPS24B 40S small subunit ribosomal protein S24.e YIL133C RPL16A 60S large subunit ribosomal protein YIL148W RPL40A ubiquitin YJL063C MRPL8 ribosomal protein L17, mitochondrial YJL096W MRPL49 ribosomal protein YmL49, mitochondrial YJL136C RPS21B 40S small subunit ribosomal protein S21.e YJL177W RPL17B 60s large subunit ribosomal protein L17.e YJL189W RPL39 60S large subunit ribosomal protein L39.e YJL190C RPS22A ribosomal protein S15a.e.c10 YJL191W RPS14B 40S small subunit ribosomal protein S14.e.B YJR094W-A RPL43B 60S large subunit ribosomal protein YJR113C RSM7 similarity to bacterial, chloroplast and mitochondrial ribosomal protein S7 YJR123W RPS5 ribosomal protein S5.e YJR145C RPS4A ribosomal protein S4.e.c10 YKL003C MRP17 ribosomal protein of the small subunit, mitochondrial YKL006W RPL14A ribosomal protein YKL009W MRT4 mRNA turnover 4 YKL056C YKL056C strong similarity to human IgE-dependent histamine-releasing factor YKL138C MRPL31 ribosomal protein YmL31, mitochondrial YKL142W MRP8 ribosomal protein, mitochondrial YKL156W RPS27A ribosomal protein S27.e YKL167C MRP49 ribosomal protein, mitochondrial YKL170W MRPL38 ribosomal protein of the large subunit (L14), mitochondrial YKL180W RPL17A ribosomal protein L17.e YKR006C MRPL13 ribosomal protein YmL13, mitochondrial YKR057W RPS21A ribosomal protein S21.e YKR085C MRPL20 ribosomal protein YmL20, mitochondrial YKR094C RPL40B ubiquitin YLL045C RPL8B 60s large subunit ribosomal protein L7a.e.B YLR009W YLR009W similarity to ribosomal protein L24.e.B YLR029C RPL15A 60s large subunit ribosomal protein L15.e.c12 YLR048W RPS0B 40S ribosomal protein p40 homolog B YLR061W RPL22A ribosomal protein YLR075W RPL10 60S large subunit ribosomal protein YLR167W RPS31 ubiquitin/40S small subunit ribosomal protein YLR185W RPL37A ribosomal protein L37.e YLR264W RPS28B 40S small subunit ribosomal protein S28.e.c12 YLR287C-A RPS30A 40S small subunit ribosomal protein YLR312W-A MRPL15 ribosomal protein of the large subunit, mitochondrial YLR325C RPL38 60S large subunit ribosomal protein YLR333C RPS25B ribosomal protein S25.e.c12 YLR340W RPP0 acidic ribosomal protein L10.e YLR344W RPL26A 60S large subunit ribosomal protein YLR367W RPS22B ribosomal protein S15a.e.c12 YLR388W RPS29A ribosomal protein S29.e.A YLR406C RPL31B 60S large subunit ribosomal protein L31.e.c12 YLR439W MRPL4 ribosomal protein, mitochondrial YLR441C RPS1A ribosomal protein S3a.e YLR448W RPL6B 60S large subunit ribosomal protein YML009C MRPL39 60S ribosomal protein, mitochondrial YML024W RPS17A ribosomal protein S17.e.A YML025C YML6 ribosomal protein, mitochondrial YML026C RPS18B ribosomal protein S18.e.c13 YML063W RPS1B ribosomal protein S3a.e YML073C RPL6A 60S large subunit ribosomal protein YMR024W MRPL3 ribosomal protein of the large subunit, mitochondrial YMR116C ASC1 40S small subunit ribosomal protein YMR121C RPL15B 60S large subunit ribosomal protein L15.e.c13 YMR142C RPL13B 60S large subunit ribosomal protein YMR143W RPS16A ribosomal protein S16.e YMR188C YMR188C weak similarity to bacterial ribosomal protein S17 YMR193W MRPL24 ribosomal protein of the large subunit, mitochondrial YMR194W RPL36A 60S large subunit ribosomal protein YMR225C MRPL44 ribosomal protein YMR44, mitochondrial YMR230W RPS10B ribosomal protein YMR242C RPL20A 60s large subunit ribosomal protein YMR286W MRPL33 ribosomal protein of the large subunit, mitochondrial YNL005C MRP7 ribosomal protein YmL2 precursor, mitochondrial YNL053W MSG5 dual-specifity protein phosphatase YNL067W RPL9B ribosomal protein L9.e.c14 YNL069C RPL16B 60S large subunit ribosomal protein YNL081C YNL081C similarity to ribosomal protein S13 YNL096C RPS7B strong similarity to ribosomal protein S7 YNL119W YNL119W weak similarity to M.jannaschii hypothetical protein MJ1257 YNL137C NAM9 ribosomal protein, mitochondrial YNL162W RPL42A ribosomal protein L36a.e YNL178W RPS3 ribosomal protein S3.e YNL185C MRPL19 ribosomal protein of the large subunit, mitochondrial YNL217W YNL217W weak similarity to E.coli bis(5'-nucleosyl)-tetraphosphatase YNL252C MRPL17 ribosomal protein of the large subunit (YmL30), mitochondrial YNL255C GIS2 strong similarity to nucleic acid-binding proteins, similarity to Tetrahymena thermophila cnjB protein YNL284C MRPL10 ribosomal protein of the large subunit, mitochondrial YNL301C RPL18B 60S large subunit ribosomal protein L18.e YNL302C RPS19B 40S small subunit ribosomal protein S19.e YNL306W MRPS18 ribosomal protein of the small subunit, mitochondrial YNR036C YNR036C strong similarity to ribosomal protein S12 YNR037C RSM19 strong similarity to Mycoplasma ribosomal protein S19 YOL039W RPP2A acidic ribosomal protein P2.beta YOL040C RPS15 40S small subunit ribosomal protein YOL120C RPL18A 60S large subunit ribosomal protein S18.e YOL121C RPS19A 40S small subunit ribosomal protein S19.e YOL127W RPL25 ribosomal protein L23a.e YOR063W RPL3 60S large subunit ribosomal protein L3.e YOR096W RPS7A ribosomal protein YOR150W MRPL23 ribosomal protein of the large subunit, mitochondrial YOR158W PET123 ribosomal protein, mitochondrial YOR167C RPS28A 40S small subunit ribosomal protein S28.e.c15 YOR182C RPS30B ribosomal protein S30 YOR234C RPL33B ribosomal protein L35a.e.c15 YOR293W RPS10A ribosomal protein S10.e YOR312C RPL20B 60S large subunit ribosomal protein YOR369C RPS12 40S small subunit acidic ribosomal protein S12 YPL013C YPL013C strong similarity to N.crassa mitochondrial ribosomal protein S24 YPL079W RPL21B ribosomal protein L21 YPL081W RPS9A ribosomal protein S9.e.A YPL090C RPS6A ribosomal protein S6.e YPL118W MRP51 mitochondrial ribosomal protein of the small subunit YPL131W RPL5 60S large subunit ribosomal protein L5.e YPL143W RPL33A ribosomal protein L35a.e.c16 YPL173W MRPL40 ribosomal protein of the large subunit (YmL40), mitochondrial YPL183W-A YPL183W-A strong similarity to mitochondrial and bacterial ribosomal L36 proteins YPL193W RSA1 nucleoplasmic protein involved in assembly of 60S ribosomal subunits YPL198W RPL7B 60S large subunit ribosomal protein YPL220W RPL1A ribosomal protein YPL249C-A RPL36B 60S large subunit ribosomal protein YPR043W RPL43A ribosomal protein L37a.e YPR102C RPL11A ribosomal protein L11.e YPR132W RPS23B 40S small subunit ribosomal protein S23.e YPR166C MRP2 ribosomal protein S14 Q0140 VAR1 mitochondrial ribosomal protein translation (64 ORFs) 05.04 64 YAL003W EFB1 translation elongation factor eEF1beta YAL035W FUN12 general translation factor eIF2 homolog YBL091C MAP2 methionine aminopeptidase, isoform 2 YBR079C RPG1 translation initiation factor eIF3 (p110 subunit) YBR118W TEF2 translation elongation factor eEF1 alpha-A chain, cytosolic YBR143C SUP45 translational release factor YDL045W-A MRP10 mitochondrial ribosomal protein YDL081C RPP1A 60S large subunit acidic ribosomal protein a1 YDR172W SUP35 eukaryotic peptide chain release factor GTP-binding subunit YDR211W GCD6 translation initiation factor eIF2b epsilon, 81 kDa subunit YDR385W EFT2 translation elongation factor eEF2 YDR429C TIF35 translation initiation factor eIF3 (p33 subunit) YEL034W HYP2 translation initiation factor eIF5A.1 YER025W GCD11 translation initiation factor eIF2 gamma chain YER165W PAB1 mRNA polyadenylate-binding protein YGL049C TIF4632 mRNA cap-binding protein (eIF4F), 130K subunit YGL094C PAN2 component of PAB1P-stimulated poly(A) ribonuclease YGL143C MRF1 peptide chain release factor, mitochondrial YGL169W SUA5 translation initiation protein YGR083C GCD2 translation initiation factor eIF2B, 71 kDa (delta) subunit YGR162W TIF4631 mRNA cap-binding protein (eIF4F), 150K subunit YGR201C YGR201C strong similarity to translation elongation factor eEF1 alpha chain CAM1P YHR015W MIP6 similarity to PES4 a PAB-like protein YJL102W MEF2 translation elongation factor, mitochondrial YJL138C TIF2 translation initiation factor eIF4A YJR007W SUI2 translation initiation factor eIF2, alpha chain YJR047C ANB1 translation initiation factor eIF5A.2 YKL081W TEF4 translation elongation factor eEF1, gamma chain YKL173W SNU114 U5 snRNP-specific protein YKL204W EAP1 translation initiation factor 4E-associated protein YKR026C GCN3 translation initiation factor eIF2B, 34 KD, alpha subunit YKR059W TIF1 translation initiation factor 4A YKR084C HBS1 translation elongation factor eEF-1 alpha chain homolog YLR005W SSL1 TFIIH subunit (transcription initiation factor), factor B YLR069C MEF1 translation elongation factor G, mitochondrial YLR249W YEF3 translation elongation factor eEF3 YLR289W GUF1 strong similarity to E. coli elongation factor-type GTP-binding protein lepa YLR291C GCD7 translation initiation factor eIF2b, 43 kDa subunit YMR012W CLU1 translation initiation factor eIF3 (p135 subunit) YMR023C MSS1 mitochondrial GTPase involved in expression of COX1 YMR116C ASC1 40S small subunit ribosomal protein YMR146C TIF34 translation initiation factor eIF3, p39 subunit YMR260C TIF11 translation initiation factor eIF1a YMR309C NIP1 associated with 40s ribosomal subunit YNL007C SIS1 heat shock protein YNL014W HEF3 translation elongation factor eEF3 homolog YNL062C GCD10 translation initiation factor eIF3 RNA-binding subunit YNL163C RIA1 translation elongation factor eEF4 YNL244C SUI1 translation initiation factor 3 (eIF3) YOL023W IFM1 translation initiation factor 2, mitochondrial YOL139C CDC33 translation initiation factor eIF4E YOR133W EFT1 translation elongation factor eEF2 YOR187W TUF1 translation elongation factor TU, mitochondrial YOR204W DED1 ATP-dependent RNA helicase YOR260W GCD1 translation initiation factor eIF2bgamma subunit YOR276W CAF20 mRNA CAP-binding protein (eIF4F), 20K subunit YOR361C PRT1 translation initiation factor eIF3 subunit YPL048W CAM1 translation elongation factor eEF1 gamma homologue YPL226W NEW1 similarity to translation elongation factor eEF3 YPL237W SUI3 translation initiation factor eIF2 beta subunit YPR016C TIF6 translation initiation factor 6 (eIF6) YPR041W TIF5 translation initiation factor eIF5 YPR080W TEF1 translation elongation factor eEF1 alpha-A chain, cytosolic YPR163C TIF3 translation initiation factor eIF4B initiation (2 ORFs) 05.04.01 2 YAL035W FUN12 general translation factor eIF2 homolog YKL204W EAP1 translation initiation factor 4E-associated protein elongation (2 ORFs) 05.04.02 2 YAL003W EFB1 translation elongation factor eEF1beta YLR069C MEF1 translation elongation factor G, mitochondrial translational control (31 ORFs) 05.07 31 YBL058W SHP1 potential regulatory subunit for GLC7P YBR024W SCO2 involved in stability of COX1P and COX2P YBR120C CBP6 apo-cytochrome B pre-mRNA processing protein YDL069C CBS1 translational activator of COB mRNA YDR197W CBS2 cytochrome B translational activator protein YDR283C GCN2 ser/thr protein kinase YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER153C PET122 translational activator of cytochrome c oxidase subunit III YFR009W GCN20 positive effector of GCN2P YGL195W GCN1 translational activator YGL236C MTO1 strong similarity to gidA E.coli protein YGR072W UPF3 nonsense-mediated mRNA decay protein YGR222W PET54 splicing protein and translational activator, mitochondrial YHR077C NMD2 nonsense-mediated mRNA decay protein 2 YJL125C GCD14 translational repressor of GCN4 YLR067C PET309 required for stability and translation of COX1 mRNA YLR203C MSS51 possibly involved in translational activation of COX1 and COB mRNA YMR023C MSS1 mitochondrial GTPase involved in expression of COX1 YMR028W TAP42 component of the Tor signaling pathway YMR064W AEP1 nuclear control of ATPase messenger RNA expression protein YMR080C NAM7 nonsense-mediated mRNA decay protein YMR257C PET111 required for translation of COX2 mRNA YMR282C AEP2 required for the expression of subunit-9 of atp synthase YNL001W DOM34 functions in protein translation to promote G1 progression and differentiation YNL139C RLR1 regulatory protein YNL216W RAP1 DNA-binding protein with repressor and activator activity YNR045W PET494 translational activator, mitochondrial YOR017W PET127 component of mitochondrial translation system YOR302W YOR302W CPA1 leader peptide YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL179W PPQ1 phosphoprotein phosphatase aminoacyl-tRNA-synthetases (37 ORFs) 05.10 37 YBL076C ILS1 isoleucyl-tRNA synthetase YBR121C GRS1 glycine--tRNA ligase YCR024C YCR024C asn-tRNA synthetase, mitochondrial YDR023W SES1 seryl-tRNA synthetase, cytosolic YDR037W KRS1 lysyl-tRNA synthetase, cytosolic YDR185C YDR185C strong similarity to MSF1P YDR268W MSW1 tryptophanyl-tRNA synthetase, mitochondrial YDR341C YDR341C arginyl-tRNA synthetase, cytosolic YER087W YER087W similarity to E.coli prolyl-tRNA synthetase YFL022C FRS2 phenylalanine--tRNA ligase beta chain, cytosolic YGL245W YGL245W strong similarity to glutamine--tRNA ligase YGR094W VAS1 valyl-tRNA synthetase YGR171C MSM1 methionyl-tRNA synthetase YGR185C TYS1 tyrosyl-tRNA synthetase YGR264C MES1 methionyl-tRNA synthetase YHR011W DIA4 strong similarity to seryl-tRNA synthetases YHR019C DED81 asparaginyl-tRNA-synthetase YHR020W YHR020W strong similarity to human glutamyl-prolyl-tRNA synthetase and fruit fly multifunctional aminoacyl-tRNA synthetase YHR091C MSR1 arginyl-tRNA synthetase, mitochondrial YIL078W THS1 threonyl tRNA synthetase, cytosolic YKL194C MST1 threonine--tRNA ligase, mitochondrial YLL018C DPS1 aspartyl-tRNA synthetase, cytosolic YLR060W FRS1 phenylalanyl-tRNA synthetase, alpha subunit, cytosolic YLR382C NAM2 leucine--tRNA ligase precursor, mitochondrial YNL073W MSK1 lysyl-tRNA synthetase, mitochondrial YNL247W YNL247W cysteinyl-tRNA synthetase YOL033W MSE1 glutamyl-tRNA synthetase, mitochondrial YOL097C WRS1 tryptophan--tRNA ligase YOR168W GLN4 glutaminyl-tRNA synthetase YOR335C ALA1 alanyl-tRNA synthetase, cytosolic YPL040C ISM1 isoleucine--tRNA ligase, mitochondrial YPL097W MSY1 tyrosyl-tRNA synthetase YPL104W MSD1 aspartate--tRNA ligase, mitochondrial YPL160W CDC60 leucine--tRNA ligase, cytosolic YPR033C HTS1 histidine--tRNA ligase, mitochondrial YPR047W MSF1 phenylalanine--tRNA ligase alpha chain, mitochondrial YPR081C YPR081C strong similarity to glycyl-tRNA synthetases other protein-synthesis activities (16 ORFs) 05.99 16 YBL080C PET112 required to maintain rho+ mitochondrial DNA YCL031C RRP7 involved in pre-rRNA processing and ribosome assembly YCL054W SPB1 required for ribosome synthesis, putative methylase YDL040C NAT1 protein N-acetyltransferase subunit YDL044C MTF2 mitochondrial protein involved in mRNA splicing and protein synthesis YDL229W SSB1 heat shock protein of HSP70 family YDR060W MAK21 protein required for 60S ribosomal subunit biogenesis YDR515W SLF1 La motif-containing proteins that modulate mRNA translation YGR147C NAT2 N-acetyltransferase for N-terminal methionine YHR038W FIL1 Killed in Mutagen, sensitive to Diepoxybutane and/or Mitomycin C YHR189W YHR189W similarity to peptidyl-tRNA hydrolases YJL023C PET130 protein synthesis protein, mitochondrial YJR066W TOR1 phosphatidylinositol 3-kinase YLL039C UBI4 ubiquitin YMR005W MPT1 required for protein synthesis YNL209W SSB2 heat shock protein of HSP70 family, cytosolic PROTEIN FATE (folding, modification, destination) (595 ORFs) 06 595 YAL002W VPS8 vacuolar sorting protein, 134 kD YAL005C SSA1 heat shock protein of HSP70 family, cytosolic YAL007C ERP2 p24 protein involved in membrane trafficking YAL023C PMT2 mannosyltransferase YAL039C CYC3 holocytochrome-c synthase (cytochrome c heme lyase) YAL048C YAL048C vacuolar aspartic proteasse YAR002C-A ERP1 p24 protein involved in membrane trafficking YBL007C SLA1 cytoskeleton assembly control protein YBL017C PEP1 vacuolar protein sorting/targeting protein YBL022C PIM1 ATP-dependent protease, mitochondrial YBL037W APL3 AP-2 complex subunit, alpha-adaptin, 113 KD YBL040C ERD2 ER lumen protein-retaining receptor YBL041W PRE7 20S proteasome subunit(beta6) YBL067C UBP13 ubiquitin carboxyl-terminal hydrolase YBL069W AST1 PMA1 protein targeting protein YBL078C AUT7 essential for autophagy YBL082C RHK1 mannosyltransferase YBL084C CDC27 subunit of anaphase-promoting complex (cyclosome) YBL091C MAP2 methionine aminopeptidase, isoform 2 YBR002C RER2 cis-prenyltransferase, a key enzyme in dolichol synthesis YBR024W SCO2 involved in stability of COX1P and COX2P YBR034C HMT1 hnRNP arginine N-methyltransferase YBR037C SCO1 involved in stabilization of COX1P and COX2P YBR044C TCM62 chaperone required for assembly of mitochondrial succinate dehydrogenase YBR058C UBP14 ubiquitin specific protease YBR059C AKL1 Ark-family Kinase-Like protein YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR091C MRS5 subunit of the TIM22-complex YBR097W VPS15 ser/thr protein kinase YBR105C VID24 required for vacuolar import and degradation of FBP1P YBR110W ALG1 beta-mannosyltransferase YBR128C APG14 required for autophagy YBR139W YBR139W strong similarity to carboxypeptidase YBR162W-A YSY6 secretory pathway protein YBR164C ARL1 ADP-ribosylation factor YBR165W UBS1 positive regulator of CDC34P YBR170C NPL4 nuclear protein localization factor and ER translocation component YBR171W SEC66 ER protein-translocation complex subunit YBR173C UMP1 proteasome maturation factor YBR185C MBA1 respiratory chain assembly protein YBR195C MSI1 chromatin assembly complex, subunit p50 YBR199W KTR4 alpha-1,2-mannosyltransferase YBR201W DER1 involved in degradation proteins in the ER YBR205W KTR3 alpha-1,2-mannosyltransferase YBR214W SDS24 strong similarity to hypothetical protein YGL056c YBR217W APG12 component of the autophagic system YBR227C MCX1 similarity to E.coli ATP-binding protein clpX YBR237W PRP5 pre-mRNA processing RNA-helicase YBR243C ALG7 UDP-N-acetylglucosamine-1-phosphate transferase YBR247C ENP1 effects N-glycosylation YBR283C SSH1 involved in co-translational pathway of protein transport YBR286W APE3 vacuolar aminopeptidase Y YCL001W RER1 required for correct localization of SEC12P YCL008C STP22 required for vacuolar targeting of temperature-sensitive plasma membrane proteins, STE2P and CAN1P YCL031C RRP7 involved in pre-rRNA processing and ribosome assembly YCL043C PDI1 protein disulfide-isomerase precursor YCL052C PBN1 required for post-translational processing of the protease B precursor PRB1P YCL057W PRD1 proteinase yscD YCR045C YCR045C similarity to serin proteases YCR066W RAD18 DNA repair protein YCR069W SCC3 peptidyl-prolyl cis-trans isomerase precursor YCR075C ERS1 intracellular protein transport protein YCR099C YCR099C strong similarity to PEP1P, VTH1P and VTH22p YCR100C YCR100C strong similarity to PEP1P, VTH1P and VTH22p YCR101C YCR101C strong similarity to PEP1P, VTH1P and VTH22p YDL007W RPT2 26S proteasome regulatory subunit YDL008W APC11 subunit of the anaphase promoting complex YDL020C RPN4 26S proteasome subunit YDL040C NAT1 protein N-acetyltransferase subunit YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL053C YDL053C hypothetical protein YDL064W UBC9 E2 ubiquitin-conjugating enzyme YDL067C COX9 cytochrome-c oxidase chain VIIA YDL077C VAM6 vacuolar carboxypeptidase Y YDL090C RAM1 protein farnesyltransferase, beta subunit YDL092W SRP14 signal recognition particle subunit YDL093W PMT5 O-mannosyltransferase similarity to PMT1P-PMT4P YDL095W PMT1 mannosyltransferase YDL097C RPN6 subunit of the regulatory particle of the proteasome YDL104C QRI7 similarity to H.influenzae sialoglycoprotease (gcp) YDL122W UBP1 ubiquitin-specific protease YDL126C CDC48 microsomal protein of CDC48/PAS1/SEC18 family of ATPases YDL132W CDC53 controls G1/S transition YDL137W ARF2 GTP-binding protein of the ARF family YDL141W BPL1 biotin holocarboxylase synthetase YDL143W CCT4 component of chaperonin-containing T-complex YDL147W RPN5 subunit of the regulatory particle of the proteasome YDL184W-A PI-SCEI homing endonuclease with protein splicing activity YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL190C UFD2 ubiquitin fusion degradation protein YDL192W ARF1 small GTP-binding protein of the ARF family YDL212W SHR3 endoplasmatic reticulum membrane protein YDL217C TIM22 subunit of the TIM22-complex YDL232W OST4 oligosaccharyltransferase subunit YDR005C MAF1 required for sorting of MOD5P YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR069C DOA4 ubiquitin-specific protease YDR079W PET100 cytochrome-c oxidase assembly protein YDR080W VPS41 required for the vacuolar assembly YDR086C SSS1 ER protein-translocase complex subunit YDR092W UBC13 E2 ubiquitin-conjugating enzyme YDR098C GRX3 member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5) YDR117C YDR117C similarity to mouse ligatin, a trafficking receptor for phosphoglycoproteins YDR118W APC4 subunit of the anaphase promoting complex YDR139C RUB1 ubiquitin-like protein YDR140W FYV9 similarity to probable methyltransferase S. pombe YDR142C PEX7 peroxisomal import protein - peroxin YDR144C MKC7 aspartyl protease of the periplasmic space YDR155C CPH1 cyclophilin (peptidylprolyl isomerase) YDR162C NBP2 NAP1P-binding protein YDR168W CDC37 cell division control protein YDR171W HSP42 heat shock protein YDR177W UBC1 E2 ubiquitin-conjugating enzyme YDR185C YDR185C strong similarity to MSF1P YDR188W CCT6 component of chaperonin-containing T-complex (zeta subunit) YDR212W TCP1 component of chaperonin-containing T-complex YDR244W PEX5 peroxisomal targeting signal receptor YDR245W MNN10 subunit of mannosyltransferase complex YDR258C HSP78 heat shock protein of clpb family of ATP-dependent proteases, mitochondrial YDR265W PEX10 peroxisomal assembly protein - peroxin YDR292C SRP101 signal recognition particle receptor, alpha chain YDR304C CYP5 peptidyl-prolyl cis-trans isomerase D precursor(cyclophilin D) of the ER YDR307W YDR307W similarity to PMT1P, PMT2P, PMT3P and PMT5P YDR322C-A TIM11 subunit E of the dimeric form of mitochondrial F1F0-ATPase YDR323C PEP7 vacuolar segregation protein YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR330W YDR330W similarity to hypothetical S. pombe protein YDR331W GPI8 essential for GPI anchor attachment YDR375C BCS1 mitochondrial protein of the CDC48/PAS1/SEC18 (AAA) family of ATPases YDR377W ATP17 ATP synthase complex, subunit f YDR389W SAC7 suppressor of actin mutation YDR390C UBA2 E1-like (ubiquitin-activating) enzyme YDR394W RPT3 26S proteasome regulatory subunit YDR409W SIZ1 E3-like factor in the SUMO pathway YDR410C STE14 farnesyl cysteine carboxyl-methyltransferase YDR414C ERD1 required for retention of luminal ER proteins YDR415C YDR415C strong similarity to bacterial leucyl aminopeptidase YDR427W RPN9 subunit of the regulatory particle of the proteasome YDR432W NPL3 nucleolar protein YDR435C PPM1 similarity to PPM2P and hypothetical C.elegans protein YDR460W TFB3 TFIIH subunit (transcription/repair factor) YDR468C TLG1 member of the syntaxin family of t-SNAREs YDR473C PRP3 essential splicing factor YDR483W KRE2 alpha-1,2-mannosyltransferase YDR495C VPS3 vacuolar sorting protein YDR498C SEC20 secretory pathway protein YDR499W LCD1 cell cycle checkpoint protein YDR510W SMT3 ubiquitin-like protein YDR518W EUG1 protein disulfide isomerase YDR519W FKB2 FK506/rapamycin-binding protein of the ER YDR529C QCR7 ubiquinol--cytochrome-c reductase subunit 7 YEL002C WBP1 oligosaccharyl transferase beta subunit precursor YEL003W GIM4 Gim complex component YEL004W YEA4 strong similarity to K.lactis golgi uridine diphosphate-N-acetylglucosamine transporter YEL012W UBC8 E2 ubiquitin-conjugating enzyme YEL013W VAC8 required for vacuole inheritance and protein targeting from the cytoplasm to vacuole YEL020W-A TIM9 essential subunit of the TIM22-complex for mitochondrial protein import YEL030W ECM10 heat shock protein of HSP70 family YEL036C ANP1 required for protein glycosylation in the golgi YEL042W GDA1 guanosine diphosphatase YEL056W HAT2 subunit of the major yeast histone acetyltransferase YEL059C-A SOM1 required for mitochondrial IMP1 peptidase function YEL060C PRB1 protease B, vacuolar YEL066W HPA3 histone and other protein acetyltransferase YER001W MNN1 alpha-1,3-mannosyltransferase YER005W YND1 Yeast Nucleoside Diphosphatase YER012W PRE1 20S proteasome subunit C11(beta4) YER017C AFG3 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YER019C-A SBH2 ER protein-translocation complex subunit YER021W RPN3 26S proteasome regulatory subunit YER047C SAP1 member of the AAA-protein family YER048C CAJ1 dnaJ homolog YER058W PET117 cytochrome c oxidase assembly factor YER078C YER078C similarity to E.coli X-Pro aminopeptidase II YER087C-B SBH1 involved in translocation into the ER YER094C PUP3 20S proteasome subunit (beta3) YER098W UBP9 ubiquitin carboxyl-terminal hydrolase YER100W UBC6 E2 ubiquitin-conjugating enzyme YER101C AST2 involved in targeting of plasma membrane [H+]ATPase YER110C KAP123 RAN-binding protein YER125W RSP5 hect domain E3 ubiquitin-protein ligase YER141W COX15 cytochrome oxidase assembly factor YER144C UBP5 ubiquitin-specific protease YER151C UBP3 ubiquitin-specific proteinase YER154W OXA1 cytochrome oxidase biogenesis protein YER174C GRX4 member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5) YFL016C MDJ1 heat shock protein - chaperone YFL033C RIM15 protein kinase involved in expression of meiotic genes YFL045C SEC53 phosphomannomutase YFR004W RPN11 26S proteasome regulatory subunit YFR006W YFR006W similarity to X-Pro dipeptidases YFR010W UBP6 ubiquitin-specific protease YFR019W FAB1 phosphatidylinositol 3-phosphate 5-kinase YFR036W CDC26 subunit of anaphase-promoting complex (cyclosome) YFR041C YFR041C weak similarity to dnaJ-like heat shock proteins YFR050C PRE4 20S proteasome subunit(beta7) YFR052W RPN12 26S proteasome regulatory subunit YGL002W ERP6 strong similarity to human gp25L2 protein YGL003C CDH1 substrate-specific activator of APC-dependent proteolysis YGL011C SCL1 20S proteasome subunit YC7ALPHA/Y8 (alpha1) YGL016W KAP122 Member of the karyopherin-beta family, nuclear import YGL017W ATE1 arginyl tRNA transferase YGL018C JAC1 molecular chaperone YGL022W STT3 oligosaccharyl transferase subunit YGL038C OCH1 alpha-1,6-mannosyltransferase YGL048C RPT6 26S proteasome regulatory subunit YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL065C ALG2 mannosyltransferase YGL095C VPS45 vacuolar protein sorting-associated protein YGL116W CDC20 cell division control protein YGL119W ABC1 ubiquinol--cytochrome-c reductase complex assembly protein YGL153W PEX14 peroxisomal protein involved in protein import - peroxin YGL155W CDC43 geranylgeranyltransferase beta subunit YGL180W APG1 essential for autophagocytosis YGL194C HOS2 putative histone deacetylase YGL203C KEX1 carboxypeptidase (YSC-alpha) YGL206C CHC1 clathrin heavy chain YGL226C-A OST5 subunit of N-oligosaccharyltransferase, zeta subunit YGL227W VID30 weak similarity to human RANBPM NP_005484.1 YGL238W CSE1 importin-beta-like protein YGL240W DOC1 component of the anaphase promoting complex YGL241W KAP114 Member of the karyopherin-beta family, nuclear import YGL257C MNT2 alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides YGR028W MSP1 intra-mitochondrial sorting protein YGR036C CAX4 required for full levels of dolichol-linked oligosaccharides in the endoplasmic reticulum YGR048W UFD1 ubiquitin fusion degradation protein YGR062C COX18 required for activity of mitochondrial cytochrome oxidase YGR074W SMD1 snRNA-associated protein YGR078C PAC10 GIM4 - Gim complex component YGR082W TOM20 mitochondrial outer membrane import receptor subunit, 20 kD YGR105W VMA21 ATPase assembly integral membrane protein YGR133W PEX4 E2 ubiquitin-conjugating enzyme - peroxin YGR135W PRE9 20S proteasome subunit Y13 (alpha3) YGR147C NAT2 N-acetyltransferase for N-terminal methionine YGR174C CBP4 ubiquinol--cytochrome-c reductase assembly factor YGR181W TIM13 Translocase of the inner membrane YGR184C UBR1 ubiquitin-protein ligase YGR199W PMT6 putative mannosyltransferase YGR209C TRX2 thioredoxin II YGR214W RPS0A 40S ribosomal protein p40 homolog A YGR232W NAS6 possible homolog of human 26S proteasome regulatory subunit p28 YGR239C PEX21 peroxin, essential for peroxisomal targeting by the PTS2 pathway YGR241C YAP1802 Yeast Adaptor Protein, member of AP180 protein family YGR252W GCN5 histone acetyltransferase YGR253C PUP2 20S proteasome subunit(alpha5) YGR270W YTA7 26S proteasome subunit YHL003C LAG1 longevity-assurance protein YHL031C GOS1 SNARE protein of Golgi compartment YHR005C-A MRS11 subunit of the TIM22-complex YHR012W VPS29 involved in vacuolar protein sorting YHR013C ARD1 protein N-acetyltransferase subunit YHR024C MAS2 processing peptidase, catalytic 53kDa (alpha) subunit, mitochondrial YHR027C RPN1 26S proteasome regulatory subunit YHR028C DAP2 dipeptidyl aminopeptidase B YHR050W SMF2 probable manganese transporter YHR057C CYP2 peptidyl-prolyl cis-trans isomerase YHR060W VMA22 vacuolar ATPase assembly protein YHR109W CTM1 cytochrome c methyltransferase YHR110W ERP5 similarity to human gp25L2 protein YHR113W YHR113W similarity to vacuolar aminopeptidase Ape1p YHR160C PEX18 peroxin, essential for peroxisomal targeting by the PTS2 pathway YHR161C YAP1801 Yeast Adaptor Protein, member of AP180 protein family YHR166C CDC23 subunit of anaphase-promoting complex (cyclosome) YHR200W RPN10 26S proteasome regulatory subunit YIL005W YIL005W similarity to protein disulfide isomerases YIL008W URM1 ubiquitin related modifier YIL014W MNT3 alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides YIL015W BAR1 barrierpepsin precursor YIL022W TIM44 mitochondrial inner membrane import receptor subunit YIL031W ULP2 SMT3P-specific protease, degrades conjugated ubiquitin-like protein SMT3P YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL075C RPN2 26S proteasome regulatory subunit YIL076W SEC28 epsilon-COP coatomer subunit YIL085C KTR7 putative alpha-1,2-mannosyltransferase YIL113W YIL113W strong similarity to dual-specificity phosphatase MSG5P YIL137C YIL137C similarity to M.musculus aminopeptidase YIL142W CCT2 chaperonin of the TCP1 ring complex, cytosolic YIL148W RPL40A ubiquitin YIL156W UBP7 ubiquitin carboxy terminal hydrolase YIL173W VTH1 strong similarity to VTH2P and PEP1P, potential membrane glycoprotein YIR004W DJP1 DnaJ-like protein involved specifically in peroxisomal protein import YIR006C PAN1 actin-cytoskeleton assembly protein YIR009W MSL1 U2 snRNA-associated protein with similarity to U2B YIR012W SQT1 suppresses dominant-negative mutants of the ribosomal protein QSR1 YIR022W SEC11 signal sequence processing protein YIR039C YPS6 GPI-anchored aspartic protease (Yapsin 6) YJL001W PRE3 20S proteasome subunit (beta1) YJL002C OST1 oligosaccharyltransferase, alpha subunit YJL008C CCT8 component of chaperonin-containing T-complex YJL014W CCT3 chaperonin of the TCP1 ring complex, cytosolic YJL031C BET4 geranylgeranyl transferase, alpha chain YJL034W KAR2 nuclear fusion protein YJL036W SNX4 weak similarity to MVP1P YJL053W PEP8 vacuolar protein sorting/targeting protein YJL054W TIM54 translocase for the insertion of proteins into the mitochondrial inner membrane YJL073W JEM1 similarity to heat shock proteins YJL111W CCT7 component of chaperonin-containing T-complex YJL125C GCD14 translational repressor of GCN4 YJL143W TIM17 mitochondrial inner membrane import translocase subunit YJL154C VPS35 protein-sorting protein, vacuolar YJL172W CPS1 Gly-X carboxypeptidase YSCS precursor YJL179W PFD1 Prefoldin subunit 1 YJL180C ATP12 F1F0-ATPase complex assembly protein YJL183W MNN11 related to MNN10P, and in a complex containing other MNN gene products YJL197W UBP12 ubiquitin C-terminal hydrolase YJL203W PRP21 pre-mRNA splicing factor YJL222W VTH2 strong similarity to PEP1P YJR005W APL1 AP-2 complex subunit, beta2-adaptin, 78 KD YJR010C-A SPC1 signal peptidase 10.8 kDa subunit YJR032W CPR7 member of the cyclophilin family YJR034W PET191 involved in assembly of cytochrome oxidase YJR045C SSC1 mitochondrial heat shock protein 70-related protein YJR058C APS2 AP-2 complex subunit, sigma2 subunit, 17 KD YJR062C NTA1 amino-terminal amidase YJR064W CCT5 T-complex protein 1, epsilon subunit YJR074W MOG1 GSP1-interacting protein YJR075W HOC1 suppressor of PKC1 YJR097W YJR097W weak similarity to CAJ1P YJR099W YUH1 ubiquitin-specific protease YJR117W STE24 zinc metallo-protease YJR131W MNS1 alpha1,2-mannosidase YJR135W-A TIM8 delivers Proteins across the intermembrane space of mitochondria to the TIM22 complex YJR143C PMT4 dolichyl-phosphate-mannose--protein O-mannosyl transferase YKL002W DID4 class E vacuolar-protein sorting and endocytosis factor YKL010C UFD4 similarity to rat ubiquitin ligase Nedd4 YKL019W RAM2 protein farnesyltransferase, alpha subunit YKL022C CDC16 subunit of anaphase-promoting complex (cyclosome) YKL035W UGP1 UTP--glucose-1-phosphate uridylyltransferase YKL041W VPS24 endosomal Vps protein complex subunit YKL073W LHS1 chaperone of the ER lumen YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL087C CYT2 holocytochrome-c1 synthase YKL103C LAP4 aminopeptidase yscI precursor, vacuolar YKL117W SBA1 Hsp90 (Ninety) Associated Co-chaperone YKL119C VPH2 H+-ATPase assembly protein YKL122C SRP21 signal recognition particle subunit YKL134C OCT1 mitochondrial intermediate peptidase YKL135C APL2 AP-1 complex subunit, beta1-adaptin, 82 KD YKL145W RPT1 26S proteasome regulatory subunit YKL154W SRP102 signal recognition particle receptor, beta chain YKL157W APE2 aminopeptidase yscII YKL176C LST4 protein required for regulated transport of nitrogen-regulated permeases from the Golgi to the plasma membrane YKL193C SDS22 regulatory subunit for the mitotic function of type I protein phosphatase YKL196C YKT6 SNARE protein for Endoplasmic Reticulum-Golgi transport YKL197C PEX1 peroxisomal assembly protein - peroxin YKL201C MNN4 regulates the mannosylphosphorylation YKL210W UBA1 E1-like (ubiquitin-activating) enzyme YKL213C DOA1 involved in ubiquitin-dependent proteolysis YKR001C VPS1 member of the dynamin family of GTPases YKR014C YPT52 GTP-binding protein of the rab family YKR035W-A DID2 class E vacuolar-protein sorting and endocytosis factor YKR038C YKR038C similarity to QRI7P YKR048C NAP1 nucleosome assembly protein I YKR094C RPL40B ubiquitin YKR098C UBP11 ubiquitin C-terminal hydrolase YLL008W DRS1 RNA helicase of the DEAD box family YLL009C COX17 interacts genetically with SCO1 and SCO2 in cytochrome oxidase assembly YLL010C PSR1 plasma membrane phosphatase involved in sodium stress response YLL024C SSA2 heat shock protein of HSP70 family, cytosolic YLL026W HSP104 heat shock protein YLL039C UBI4 ubiquitin YLL040C VPS13 involved in regulating membrane traffic YLL042C APG10 protein-conjugating enzyme essential for autophagy YLL050C COF1 cofilin, actin binding and severing protein YLR002C NOC3 required for maturation and intranuclear transport of pre-ribosomes YLR019W PSR2 plasma membrane phosphatase required for sodium stress response YLR025W SNF7 class E Vps protein YLR038C COX12 cytochrome-c oxidase, subunit VIB YLR043C TRX1 thioredoxin I YLR048W RPS0B 40S ribosomal protein p40 homolog B YLR066W SPC3 signal peptidase subunit YLR075W RPL10 60S large subunit ribosomal protein YLR088W GAA1 required for attachment of GPI anchor onto proteins YLR090W XDJ1 similarity to E.coli dnaJ YLR093C NYV1 v-SNARE, vacuolar YLR102C APC9 subunit of the Anaphase Promoting Complex YLR120C YPS1 aspergillopepsin YLR121C YPS3 GPI-anchored aspartyl protease 3 (yapsin 3) YLR127C APC2 component of the anaphase promoting complex YLR144C ACF2 necessary for cortical actin assembly YLR148W PEP3 vacuolar membrane protein YLR163C MAS1 mitochondrial processing peptidase YLR167W RPS31 ubiquitin/40S small subunit ribosomal protein YLR168C (MSF1) probably involved in intramitochondrial protein sorting YLR170C APS1 AP-1 complex subunit, sigma1 subunit, 18 KD YLR191W PEX13 peroxisomal protein involved in protein import - peroxin YLR195C NMT1 N-myristoyltransferase YLR200W YKE2 Gim complex component YLR207W HRD3 involved in degradation of HMG2P YLR216C CPR6 member of the cyclophilin family YLR244C MAP1 methionine aminopeptidase, isoform 1 YLR246W ERF2 protein involved in palmitoylation and localization of RAS2P YLR259C HSP60 heat shock protein - chaperone, mitochondrial YLR292C SEC72 ER protein-translocation complex subunit YLR306W UBC12 E2 ubiquitin-conjugating enzyme YLR309C IMH1 involved in vesicular transport YLR327C YLR327C strong similarity to STF2P YLR347C KAP95 karyopherin-beta YLR360W VPS38 protein involved in vacuolar sorting YLR369W SSQ1 mitochondrial heat shock protein 70 YLR378C SEC61 ER protein-translocation complex subunit YLR387C YLR387C similarity to YBR267w YLR389C STE23 protease involved in a-factor processing YLR393W ATP10 F1F0 ATPase complex assembly protein YLR396C VPS33 vacuolar sorting protein YLR410W VIP1 strong similarity to S. pombe protein ASP1P YLR417W VPS36 defective in vacuolar protein sorting YLR423C APG17 protein involved in authophagy YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YLR449W FPR4 nucleolar peptidylprolyl cis-trans isomerase (PPIase) YLR452C SST2 involved in desensitization to alpha-factor pheromone YML019W OST6 N-oligosaccharyltransferase complex subunit YML055W SPC2 signal peptidase 18 KD subunit YML062C MFT1 mitochondrial fusion target protein YML074C NPI46 proline cis-trans isomerase YML078W CPR3 cyclophilin (peptidylprolyl isomerase), mitochondrial YML088W UFO1 involved in degradation of HO protein YML092C PRE8 20S proteasome subunit Y7 (alpha2) YML094W GIM5 Gim complex component YML097C VPS9 vacuolar sorting protein YML102W CAC2 chromatin assembly complex, subunit p60 YML105C SEC65 signal recognition particle subunit YML111W BUL2 strong similarity to ubiquitination protein BUL1P YML115C VAN1 vanadate resistance protein YML129C COX14 cytochrome-c oxidase assembly protein YML130C ERO1 required for protein disulfide bond formation in the ER YMR004W MVP1 required for vacuolar protein sorting YMR018W YMR018W similarity to tetratricopeptide-repeat protein PAS10 YMR022W QRI8 E2 ubiquitin-conjugation enzyme YMR035W IMP2 mitochondrial inner membrane protease subunit YMR038C LYS7 copper chaperone for superoxide dismutase SOD1P YMR060C TOM37 mitochondrial outer membrane import receptor subunit, 37 kD YMR089C YTA12 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YMR091C NPL6 nuclear protein localization factor YMR101C SRT1 cis-prenyltransferase homologue YMR149W SWP1 oligosaccharyltransferase delta subunit YMR150C IMP1 protease, mitochondrial YMR152W YIM1 mitochondrial inner membrane protease YMR154C RIM13 calpain-like cysteine protease YMR159C APG16 coiled-coil protein required for autophagy YMR161W HLJ1 similarity to dnaJ proteins YMR174C PAI3 protease A (ysca) inhibitor IA3 YMR197C VTI1 v-SNARE: involved in Golgi retrograde protein traffic YMR203W TOM40 forms the hydrophilic channel of the mitochondrial import pore for preproteins YMR214W SCJ1 homolog of E. coli DnaJ, functions in the endoplasmic reticulum by interaction with KAR2P YMR223W UBP8 similarity to mouse deubiquitinating enzyme and UBP13P,UBP9,DOA4P YMR231W PEP5 vacuolar biogenesis protein YMR246W FAA4 long-chain-fatty-acid--CoA ligase YMR256C COX7 cytochrome-c oxidase, subunit VII YMR264W CUE1 involved in ubiquitination and degradation at the ER surface YMR274C RCE1 modulator of RAS2P YMR275C BUL1 ubiquitination pathway protein YMR292W GOT1 Membrane protein required for ER to Golgi transport YMR297W PRC1 carboxypeptidase y, serine-type protease YMR304W UBP15 similarity to human ubiquitin-specific protease YMR314W PRE5 20S proteasome subunit(alpha6) YNL015W PBI2 proteinase B inhibitor 2 YNL021W HDA1 histone deacetylase A YNL029C KTR5 putative mannosyltransferase YNL048W ALG11 required for asparagine-linked glycosylation YNL054W VAC7 vacuolar protein YNL064C YDJ1 mitochondrial and ER import protein YNL070W TOM7 mitochondrial outer membrane import receptor subunit, 7 kD YNL077W YNL077W similarity to dnaJ protein homolog YDJ1 YNL093W YPT53 GTP-binding protein of the RAB family (RAS superfamily) YNL121C TOM70 mitochondrial outer membrane specialized import receptor YNL131W TOM22 mitochondrial outer membrane import receptor complex subunit YNL135C FPR1 peptidyl-prolyl cis-trans isomerase, FK506-binding protein YNL148C ALF1 similarity to human tubulin folding cofactor B YNL153C GIM3 Gim complex component YNL172W APC1 subunit of anaphase-promoting complex (cyclosome) YNL186W UBP10 derepression of telomeric silencing YNL189W SRP1 karyopherin-alpha or importin YNL223W AUT2 essential for autophagy YNL227C YNL227C similarity to dnaJ-like proteins YNL233W BNI4 bud neck involved YNL238W KEX2 endoproteinase of late golgi compartment YNL239W LAP3 member of the GAL regulon YNL243W SLA2 cytoskeleton assembly control protein YNL315C ATP11 F1F0-ATPase complex assembly protein YNL328C MDJ2 heat shock protein - chaperone YNL329C PEX6 peroxisomal assembly protein YNR006W VPS27 vacuolar protein sorting-associated protein YNR007C AUT1 essential for autophagocytosis YNR017W MAS6 mitochondrial inner membrane import translocase subunit YNR028W CPR8 Cyclophilin (peptidylprolyl cis-trans isomerase or PPIase) YNR038W DBP6 RNA helicase required for 60S ribosomal subunit assembly YNR059W MNT4 similarity to to alpha-1,3-mannosyltransferase YNR069C YNR069C similarity to central part of BUL1P YOL013C HRD1 involved in degradation of HMG2P YOL018C TLG2 member of the syntaxin family of t-SNAREs YOL031C YOL031C weak similarity to Y.lipolytica SLS1 protein precursor YOL038W PRE6 20S proteasome subunit (alpha4) YOL062C APM4 AP-2 complex subunit, mu2 subunit, 55 KD YOL088C MPD2 protein disulfide isomerase-related protein YOL111C YOL111C weak similarity to human ubiquitin-like protein GDX YOL122C SMF1 manganese transporter YOL141W PPM2 similarity to YDR435c and C.elegans hypothetical protein YOL144W NOP8 nucleolar protein required for 60S ribosome biogenesis YOL153C YOL153C strong similarity to CPS1P YOR002W ALG6 glucosyltransferase YOR003W YSP3 subtilisin-like protease III YOR016C ERP4 similarity to human COP-coated vesicle membrane protein YOR020C HSP10 chaperonin, mitochondrial YOR023C AHC1 component of the ADA histone acetyltransferase complex YOR036W PEP12 syntaxin (T-SNARE), vacuolar YOR045W TOM6 mitochondrial outer membrane import receptor subunit, 6 kD YOR057W SGT1 suppressor of G2 allele of SKP1 YOR064C YNG1 component of histone acetyltransferase complex, has similarity to human retinoblastoma binding protein 2 YOR067C ALG8 glucosyltransferase YOR069W VPS5 involved in Golgi retention and vacuolar sorting YOR085W OST3 oligosaccharyltransferase gamma subunit YOR089C VPS21 GTP-binding protein YOR090C PTC5 putative 2C protein phosphatase (PP2Cs) YOR094W ARF3 ADP-ribosylation factor 3 YOR099W KTR1 mannosyltransferase involved in n-linked and o-linked glycosylation YOR103C OST2 oligosaccharyltransferase epsilon subunit YOR106W VAM3 syntaxin (t-SNARE) YOR117W RPT5 26S proteasome regulatory subunit YOR123C LEO1 extremely hydrophilic protein YOR124C UBP2 ubiquitin-specific proteinase YOR132W VPS17 vacuolar protein sorting-associated protein YOR134W BAG7 structural homolog of SAC7P YOR157C PUP1 20S proteasome subunit (beta2) YOR181W LAS17 component of actin cortical patches YOR219C STE13 type IV dipeptidyl aminopeptidase YOR232W MGE1 heat shock protein - chaperone YOR244W ESA1 histone acetyltransferase YOR249C APC5 component of the anaphase-promoting complex YOR254C SEC63 ER protein-translocation complex subunit YOR259C RPT4 26S proteasome regulatory subunit YOR261C RPN8 26S proteasome regulatory subunit YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR285W YOR285W similarity to D.melanogaster heat shock protein 67B2 YOR286W YOR286W similarity to D.melanogaster heat shock protein 67B2 YOR288C MPD1 disulfide isomerase related protein YOR297C TIM18 component of the inner mitochondrial membrane translocation complex YOR321W PMT3 mannosyltransferase YOR327C SNC2 synaptobrevin (v-SNARE) homolog present on post-Golgi vesicles YOR329C SCD5 suppressor of clathrin deficiency YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YOR339C UBC11 strong similarity to E2 ubiquitin-conjugating enzymes YOR357C GRD19 involved in retrieval of late Golgi membrane proteins from the prevacuolar compartment YOR362C PRE10 20S proteasome subunit C1 (alpha7) YOR370C MRS6 geranylgeranyltransferase regulatory subunit YPL001W HAT1 histone acetyltransferase subunit YPL003W ULA1 involved in protein modification YPL020C ULP1 Ubl-specific protease YPL037C EGD1 GAL4 DNA-binding enhancer protein YPL045W VPS16 vacuolar sorting protein YPL050C MNN9 required for complex N-glycosylation YPL051W ARL3 ADP-ribosylation factor-like protein, member of the arf-sar family in the ras superfamily YPL053C KTR6 mannosylphosphate transferase YPL059W GRX5 member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5) YPL072W UBP16 weak similarity to UBP11P YPL074W YTA6 similarity to VPS4P and YER047c YPL085W SEC16 multidomain vesicle coat protein YPL086C ELP3 subunit of elongator/RNAPII holoenzyme with histone acetylase activity YPL094C SEC62 ER protein-translocation complex subunit YPL096W PNG1 protein with de-N-glycosylation function YPL120W VPS30 involved in vacuolare protein sorting and autophagy YPL125W KAP120 nuclear transport factor, member of karyopherin-beta family YPL132W COX11 cytochrome-c oxidase assembly protein YPL148C PPT2 phosphopantetheine protein transferase YPL149W APG5 involved in autophagy and nutrient starvation YPL154C PEP4 aspartyl protease YPL172C COX10 farnesyl transferase YPL210C SRP72 signal recognition particle protein YPL213W LEA1 U2 A' snRNP protein YPL215W CBP3 required for assembly of cytochrome bc1 complex YPL227C ALG5 dolichol-P-glucose synthetase YPL231W FAS2 fatty-acyl-CoA synthase, alpha chain YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPL243W SRP68 signal recognition particle protein YPL259C APM1 AP-1 complex subunit, mu1 subunit, 54 KD YPR018W RLF2 chromatin assembly complex, subunit p90 YPR024W YME1 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YPR029C APL4 AP-1 complex subunit, gamma-adaptin, 94 KD YPR047W MSF1 phenylalanine--tRNA ligase alpha chain, mitochondrial YPR051W MAK3 N-acetyltransferase YPR066W UBA3 ubiquitin-like protein activating enzyme YPR088C SRP54 signal recognition particle subunit YPR103W PRE2 20S proteasome subunit (beta5) YPR108W RPN7 subunit of the regulatory particle of the proteasome YPR122W AXL1 protease YPR131C NAT3 N-acetyltransferases YPR141C KAR3 kinesin-related protein YPR173C VPS4 vacuolar sorting protein YPR176C BET2 geranylgeranyltransferase type II beta subunit YPR178W PRP4 U4/U6 snRNP 52 KD protein YPR180W AOS1 forms together with UBA2P a heterodimeric activating enzyme for SMT3P YPR185W APG13 protein required for the autophagic process YPR191W QCR2 ubiquinol--cytochrome-c reductase 40KD chain II YPR193C HPA2 Histone and other Protein Acetyltransferase protein folding and stabilization (59 ORFs) 06.01 59 YAL005C SSA1 heat shock protein of HSP70 family, cytosolic YCL043C PDI1 protein disulfide-isomerase precursor YCR069W SCC3 peptidyl-prolyl cis-trans isomerase precursor YDL143W CCT4 component of chaperonin-containing T-complex YDR155C CPH1 cyclophilin (peptidylprolyl isomerase) YDR168W CDC37 cell division control protein YDR171W HSP42 heat shock protein YDR188W CCT6 component of chaperonin-containing T-complex (zeta subunit) YDR212W TCP1 component of chaperonin-containing T-complex YDR304C CYP5 peptidyl-prolyl cis-trans isomerase D precursor(cyclophilin D) of the ER YDR518W EUG1 protein disulfide isomerase YDR519W FKB2 FK506/rapamycin-binding protein of the ER YEL003W GIM4 Gim complex component YEL030W ECM10 heat shock protein of HSP70 family YER048C CAJ1 dnaJ homolog YFL016C MDJ1 heat shock protein - chaperone YFR041C YFR041C weak similarity to dnaJ-like heat shock proteins YGL018C JAC1 molecular chaperone YGR078C PAC10 GIM4 - Gim complex component YHR057C CYP2 peptidyl-prolyl cis-trans isomerase YIL005W YIL005W similarity to protein disulfide isomerases YIL142W CCT2 chaperonin of the TCP1 ring complex, cytosolic YIR004W DJP1 DnaJ-like protein involved specifically in peroxisomal protein import YJL008C CCT8 component of chaperonin-containing T-complex YJL014W CCT3 chaperonin of the TCP1 ring complex, cytosolic YJL034W KAR2 nuclear fusion protein YJL073W JEM1 similarity to heat shock proteins YJL111W CCT7 component of chaperonin-containing T-complex YJL179W PFD1 Prefoldin subunit 1 YJR032W CPR7 member of the cyclophilin family YJR045C SSC1 mitochondrial heat shock protein 70-related protein YJR064W CCT5 T-complex protein 1, epsilon subunit YJR097W YJR097W weak similarity to CAJ1P YJR135W-A TIM8 delivers Proteins across the intermembrane space of mitochondria to the TIM22 complex YKL073W LHS1 chaperone of the ER lumen YKL117W SBA1 Hsp90 (Ninety) Associated Co-chaperone YLL024C SSA2 heat shock protein of HSP70 family, cytosolic YLR090W XDJ1 similarity to E.coli dnaJ YLR200W YKE2 Gim complex component YLR216C CPR6 member of the cyclophilin family YLR259C HSP60 heat shock protein - chaperone, mitochondrial YLR369W SSQ1 mitochondrial heat shock protein 70 YLR449W FPR4 nucleolar peptidylprolyl cis-trans isomerase (PPIase) YML074C NPI46 proline cis-trans isomerase YML078W CPR3 cyclophilin (peptidylprolyl isomerase), mitochondrial YML094W GIM5 Gim complex component YMR154C RIM13 calpain-like cysteine protease YMR161W HLJ1 similarity to dnaJ proteins YNL077W YNL077W similarity to dnaJ protein homolog YDJ1 YNL135C FPR1 peptidyl-prolyl cis-trans isomerase, FK506-binding protein YNL148C ALF1 similarity to human tubulin folding cofactor B YNL153C GIM3 Gim complex component YNL227C YNL227C similarity to dnaJ-like proteins YNL328C MDJ2 heat shock protein - chaperone YNR028W CPR8 Cyclophilin (peptidylprolyl cis-trans isomerase or PPIase) YOL031C YOL031C weak similarity to Y.lipolytica SLS1 protein precursor YOL088C MPD2 protein disulfide isomerase-related protein YOR232W MGE1 heat shock protein - chaperone YOR288C MPD1 disulfide isomerase related protein protein targeting, sorting and translocation (146 ORFs) 06.04 146 YAL002W VPS8 vacuolar sorting protein, 134 kD YAL005C SSA1 heat shock protein of HSP70 family, cytosolic YAL007C ERP2 p24 protein involved in membrane trafficking YAR002C-A ERP1 p24 protein involved in membrane trafficking YBL017C PEP1 vacuolar protein sorting/targeting protein YBL040C ERD2 ER lumen protein-retaining receptor YBL069W AST1 PMA1 protein targeting protein YBR091C MRS5 subunit of the TIM22-complex YBR097W VPS15 ser/thr protein kinase YBR162W-A YSY6 secretory pathway protein YBR170C NPL4 nuclear protein localization factor and ER translocation component YBR171W SEC66 ER protein-translocation complex subunit YBR283C SSH1 involved in co-translational pathway of protein transport YCL001W RER1 required for correct localization of SEC12P YCR075C ERS1 intracellular protein transport protein YCR099C YCR099C strong similarity to PEP1P, VTH1P and VTH22p YCR100C YCR100C strong similarity to PEP1P, VTH1P and VTH22p YCR101C YCR101C strong similarity to PEP1P, VTH1P and VTH22p YDL092W SRP14 signal recognition particle subunit YDL212W SHR3 endoplasmatic reticulum membrane protein YDL217C TIM22 subunit of the TIM22-complex YDR005C MAF1 required for sorting of MOD5P YDR086C SSS1 ER protein-translocase complex subunit YDR117C YDR117C similarity to mouse ligatin, a trafficking receptor for phosphoglycoproteins YDR142C PEX7 peroxisomal import protein - peroxin YDR185C YDR185C strong similarity to MSF1P YDR244W PEX5 peroxisomal targeting signal receptor YDR292C SRP101 signal recognition particle receptor, alpha chain YDR323C PEP7 vacuolar segregation protein YDR414C ERD1 required for retention of luminal ER proteins YDR432W NPL3 nucleolar protein YDR468C TLG1 member of the syntaxin family of t-SNAREs YDR495C VPS3 vacuolar sorting protein YDR498C SEC20 secretory pathway protein YEL013W VAC8 required for vacuole inheritance and protein targeting from the cytoplasm to vacuole YEL020W-A TIM9 essential subunit of the TIM22-complex for mitochondrial protein import YEL059C-A SOM1 required for mitochondrial IMP1 peptidase function YER019C-A SBH2 ER protein-translocation complex subunit YER087C-B SBH1 involved in translocation into the ER YER101C AST2 involved in targeting of plasma membrane [H+]ATPase YER110C KAP123 RAN-binding protein YFR019W FAB1 phosphatidylinositol 3-phosphate 5-kinase YGL002W ERP6 strong similarity to human gp25L2 protein YGL016W KAP122 Member of the karyopherin-beta family, nuclear import YGL095C VPS45 vacuolar protein sorting-associated protein YGL153W PEX14 peroxisomal protein involved in protein import - peroxin YGL206C CHC1 clathrin heavy chain YGL238W CSE1 importin-beta-like protein YGL241W KAP114 Member of the karyopherin-beta family, nuclear import YGR028W MSP1 intra-mitochondrial sorting protein YGR082W TOM20 mitochondrial outer membrane import receptor subunit, 20 kD YGR181W TIM13 Translocase of the inner membrane YGR239C PEX21 peroxin, essential for peroxisomal targeting by the PTS2 pathway YHL003C LAG1 longevity-assurance protein YHL031C GOS1 SNARE protein of Golgi compartment YHR005C-A MRS11 subunit of the TIM22-complex YHR012W VPS29 involved in vacuolar protein sorting YHR050W SMF2 probable manganese transporter YHR110W ERP5 similarity to human gp25L2 protein YHR160C PEX18 peroxin, essential for peroxisomal targeting by the PTS2 pathway YIL022W TIM44 mitochondrial inner membrane import receptor subunit YIL076W SEC28 epsilon-COP coatomer subunit YIL173W VTH1 strong similarity to VTH2P and PEP1P, potential membrane glycoprotein YJL034W KAR2 nuclear fusion protein YJL053W PEP8 vacuolar protein sorting/targeting protein YJL054W TIM54 translocase for the insertion of proteins into the mitochondrial inner membrane YJL143W TIM17 mitochondrial inner membrane import translocase subunit YJL154C VPS35 protein-sorting protein, vacuolar YJL222W VTH2 strong similarity to PEP1P YJR074W MOG1 GSP1-interacting protein YJR135W-A TIM8 delivers Proteins across the intermembrane space of mitochondria to the TIM22 complex YKL002W DID4 class E vacuolar-protein sorting and endocytosis factor YKL041W VPS24 endosomal Vps protein complex subunit YKL073W LHS1 chaperone of the ER lumen YKL122C SRP21 signal recognition particle subunit YKL154W SRP102 signal recognition particle receptor, beta chain YKL176C LST4 protein required for regulated transport of nitrogen-regulated permeases from the Golgi to the plasma membrane YKL196C YKT6 SNARE protein for Endoplasmic Reticulum-Golgi transport YKR001C VPS1 member of the dynamin family of GTPases YKR014C YPT52 GTP-binding protein of the rab family YKR035W-A DID2 class E vacuolar-protein sorting and endocytosis factor YLL024C SSA2 heat shock protein of HSP70 family, cytosolic YLL040C VPS13 involved in regulating membrane traffic YLR025W SNF7 class E Vps protein YLR148W PEP3 vacuolar membrane protein YLR168C (MSF1) probably involved in intramitochondrial protein sorting YLR191W PEX13 peroxisomal protein involved in protein import - peroxin YLR292C SEC72 ER protein-translocation complex subunit YLR309C IMH1 involved in vesicular transport YLR347C KAP95 karyopherin-beta YLR360W VPS38 protein involved in vacuolar sorting YLR378C SEC61 ER protein-translocation complex subunit YLR396C VPS33 vacuolar sorting protein YLR417W VPS36 defective in vacuolar protein sorting YML062C MFT1 mitochondrial fusion target protein YML097C VPS9 vacuolar sorting protein YML105C SEC65 signal recognition particle subunit YMR004W MVP1 required for vacuolar protein sorting YMR018W YMR018W similarity to tetratricopeptide-repeat protein PAS10 YMR035W IMP2 mitochondrial inner membrane protease subunit YMR060C TOM37 mitochondrial outer membrane import receptor subunit, 37 kD YMR091C NPL6 nuclear protein localization factor YMR150C IMP1 protease, mitochondrial YMR197C VTI1 v-SNARE: involved in Golgi retrograde protein traffic YMR203W TOM40 forms the hydrophilic channel of the mitochondrial import pore for preproteins YMR214W SCJ1 homolog of E. coli DnaJ, functions in the endoplasmic reticulum by interaction with KAR2P YMR231W PEP5 vacuolar biogenesis protein YMR292W GOT1 Membrane protein required for ER to Golgi transport YNL054W VAC7 vacuolar protein YNL064C YDJ1 mitochondrial and ER import protein YNL070W TOM7 mitochondrial outer membrane import receptor subunit, 7 kD YNL093W YPT53 GTP-binding protein of the RAB family (RAS superfamily) YNL121C TOM70 mitochondrial outer membrane specialized import receptor YNL131W TOM22 mitochondrial outer membrane import receptor complex subunit YNL189W SRP1 karyopherin-alpha or importin YNR006W VPS27 vacuolar protein sorting-associated protein YNR017W MAS6 mitochondrial inner membrane import translocase subunit YOL018C TLG2 member of the syntaxin family of t-SNAREs YOL031C YOL031C weak similarity to Y.lipolytica SLS1 protein precursor YOL062C APM4 AP-2 complex subunit, mu2 subunit, 55 KD YOL122C SMF1 manganese transporter YOR016C ERP4 similarity to human COP-coated vesicle membrane protein YOR020C HSP10 chaperonin, mitochondrial YOR036W PEP12 syntaxin (T-SNARE), vacuolar YOR045W TOM6 mitochondrial outer membrane import receptor subunit, 6 kD YOR069W VPS5 involved in Golgi retention and vacuolar sorting YOR089C VPS21 GTP-binding protein YOR132W VPS17 vacuolar protein sorting-associated protein YOR254C SEC63 ER protein-translocation complex subunit YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR285W YOR285W similarity to D.melanogaster heat shock protein 67B2 YOR286W YOR286W similarity to D.melanogaster heat shock protein 67B2 YOR297C TIM18 component of the inner mitochondrial membrane translocation complex YOR327C SNC2 synaptobrevin (v-SNARE) homolog present on post-Golgi vesicles YOR329C SCD5 suppressor of clathrin deficiency YOR357C GRD19 involved in retrieval of late Golgi membrane proteins from the prevacuolar compartment YPL037C EGD1 GAL4 DNA-binding enhancer protein YPL045W VPS16 vacuolar sorting protein YPL094C SEC62 ER protein-translocation complex subunit YPL125W KAP120 nuclear transport factor, member of karyopherin-beta family YPL210C SRP72 signal recognition particle protein YPL243W SRP68 signal recognition particle protein YPL259C APM1 AP-1 complex subunit, mu1 subunit, 54 KD YPR047W MSF1 phenylalanine--tRNA ligase alpha chain, mitochondrial YPR088C SRP54 signal recognition particle subunit YPR173C VPS4 vacuolar sorting protein protein modification (187 ORFs) 06.07 187 YAL023C PMT2 mannosyltransferase YAL039C CYC3 holocytochrome-c synthase (cytochrome c heme lyase) YAL048C YAL048C vacuolar aspartic proteasse YBL082C RHK1 mannosyltransferase YBL084C CDC27 subunit of anaphase-promoting complex (cyclosome) YBL091C MAP2 methionine aminopeptidase, isoform 2 YBR002C RER2 cis-prenyltransferase, a key enzyme in dolichol synthesis YBR034C HMT1 hnRNP arginine N-methyltransferase YBR059C AKL1 Ark-family Kinase-Like protein YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR110W ALG1 beta-mannosyltransferase YBR164C ARL1 ADP-ribosylation factor YBR199W KTR4 alpha-1,2-mannosyltransferase YBR205W KTR3 alpha-1,2-mannosyltransferase YBR243C ALG7 UDP-N-acetylglucosamine-1-phosphate transferase YBR247C ENP1 effects N-glycosylation YCL043C PDI1 protein disulfide-isomerase precursor YCL052C PBN1 required for post-translational processing of the protease B precursor PRB1P YCR066W RAD18 DNA repair protein YDL008W APC11 subunit of the anaphase promoting complex YDL040C NAT1 protein N-acetyltransferase subunit YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL064W UBC9 E2 ubiquitin-conjugating enzyme YDL090C RAM1 protein farnesyltransferase, beta subunit YDL093W PMT5 O-mannosyltransferase similarity to PMT1P-PMT4P YDL095W PMT1 mannosyltransferase YDL132W CDC53 controls G1/S transition YDL141W BPL1 biotin holocarboxylase synthetase YDL212W SHR3 endoplasmatic reticulum membrane protein YDL232W OST4 oligosaccharyltransferase subunit YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR092W UBC13 E2 ubiquitin-conjugating enzyme YDR098C GRX3 member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5) YDR118W APC4 subunit of the anaphase promoting complex YDR139C RUB1 ubiquitin-like protein YDR140W FYV9 similarity to probable methyltransferase S. pombe YDR177W UBC1 E2 ubiquitin-conjugating enzyme YDR245W MNN10 subunit of mannosyltransferase complex YDR307W YDR307W similarity to PMT1P, PMT2P, PMT3P and PMT5P YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR331W GPI8 essential for GPI anchor attachment YDR390C UBA2 E1-like (ubiquitin-activating) enzyme YDR410C STE14 farnesyl cysteine carboxyl-methyltransferase YDR414C ERD1 required for retention of luminal ER proteins YDR435C PPM1 similarity to PPM2P and hypothetical C.elegans protein YDR483W KRE2 alpha-1,2-mannosyltransferase YDR495C VPS3 vacuolar sorting protein YDR499W LCD1 cell cycle checkpoint protein YDR510W SMT3 ubiquitin-like protein YEL002C WBP1 oligosaccharyl transferase beta subunit precursor YEL004W YEA4 strong similarity to K.lactis golgi uridine diphosphate-N-acetylglucosamine transporter YEL012W UBC8 E2 ubiquitin-conjugating enzyme YEL036C ANP1 required for protein glycosylation in the golgi YEL042W GDA1 guanosine diphosphatase YEL056W HAT2 subunit of the major yeast histone acetyltransferase YEL060C PRB1 protease B, vacuolar YEL066W HPA3 histone and other protein acetyltransferase YER001W MNN1 alpha-1,3-mannosyltransferase YER005W YND1 Yeast Nucleoside Diphosphatase YER100W UBC6 E2 ubiquitin-conjugating enzyme YER125W RSP5 hect domain E3 ubiquitin-protein ligase YER174C GRX4 member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5) YFL033C RIM15 protein kinase involved in expression of meiotic genes YFL045C SEC53 phosphomannomutase YFR010W UBP6 ubiquitin-specific protease YFR036W CDC26 subunit of anaphase-promoting complex (cyclosome) YGL017W ATE1 arginyl tRNA transferase YGL022W STT3 oligosaccharyl transferase subunit YGL038C OCH1 alpha-1,6-mannosyltransferase YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL065C ALG2 mannosyltransferase YGL155W CDC43 geranylgeranyltransferase beta subunit YGL194C HOS2 putative histone deacetylase YGL203C KEX1 carboxypeptidase (YSC-alpha) YGL226C-A OST5 subunit of N-oligosaccharyltransferase, zeta subunit YGL240W DOC1 component of the anaphase promoting complex YGL257C MNT2 alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides YGR036C CAX4 required for full levels of dolichol-linked oligosaccharides in the endoplasmic reticulum YGR133W PEX4 E2 ubiquitin-conjugating enzyme - peroxin YGR147C NAT2 N-acetyltransferase for N-terminal methionine YGR199W PMT6 putative mannosyltransferase YGR209C TRX2 thioredoxin II YGR252W GCN5 histone acetyltransferase YHR013C ARD1 protein N-acetyltransferase subunit YHR024C MAS2 processing peptidase, catalytic 53kDa (alpha) subunit, mitochondrial YHR109W CTM1 cytochrome c methyltransferase YHR166C CDC23 subunit of anaphase-promoting complex (cyclosome) YIL008W URM1 ubiquitin related modifier YIL014W MNT3 alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides YIL031W ULP2 SMT3P-specific protease, degrades conjugated ubiquitin-like protein SMT3P YIL085C KTR7 putative alpha-1,2-mannosyltransferase YIL113W YIL113W strong similarity to dual-specificity phosphatase MSG5P YIR022W SEC11 signal sequence processing protein YIR039C YPS6 GPI-anchored aspartic protease (Yapsin 6) YJL002C OST1 oligosaccharyltransferase, alpha subunit YJL031C BET4 geranylgeranyl transferase, alpha chain YJL125C GCD14 translational repressor of GCN4 YJL183W MNN11 related to MNN10P, and in a complex containing other MNN gene products YJR010C-A SPC1 signal peptidase 10.8 kDa subunit YJR062C NTA1 amino-terminal amidase YJR075W HOC1 suppressor of PKC1 YJR099W YUH1 ubiquitin-specific protease YJR117W STE24 zinc metallo-protease YJR131W MNS1 alpha1,2-mannosidase YJR143C PMT4 dolichyl-phosphate-mannose--protein O-mannosyl transferase YKL019W RAM2 protein farnesyltransferase, alpha subunit YKL022C CDC16 subunit of anaphase-promoting complex (cyclosome) YKL035W UGP1 UTP--glucose-1-phosphate uridylyltransferase YKL087C CYT2 holocytochrome-c1 synthase YKL134C OCT1 mitochondrial intermediate peptidase YKL157W APE2 aminopeptidase yscII YKL193C SDS22 regulatory subunit for the mitotic function of type I protein phosphatase YKL201C MNN4 regulates the mannosylphosphorylation YKL210W UBA1 E1-like (ubiquitin-activating) enzyme YLL010C PSR1 plasma membrane phosphatase involved in sodium stress response YLL042C APG10 protein-conjugating enzyme essential for autophagy YLR019W PSR2 plasma membrane phosphatase required for sodium stress response YLR043C TRX1 thioredoxin I YLR066W SPC3 signal peptidase subunit YLR088W GAA1 required for attachment of GPI anchor onto proteins YLR102C APC9 subunit of the Anaphase Promoting Complex YLR120C YPS1 aspergillopepsin YLR127C APC2 component of the anaphase promoting complex YLR163C MAS1 mitochondrial processing peptidase YLR195C NMT1 N-myristoyltransferase YLR244C MAP1 methionine aminopeptidase, isoform 1 YLR246W ERF2 protein involved in palmitoylation and localization of RAS2P YLR306W UBC12 E2 ubiquitin-conjugating enzyme YLR369W SSQ1 mitochondrial heat shock protein 70 YLR389C STE23 protease involved in a-factor processing YLR410W VIP1 strong similarity to S. pombe protein ASP1P YML019W OST6 N-oligosaccharyltransferase complex subunit YML055W SPC2 signal peptidase 18 KD subunit YML111W BUL2 strong similarity to ubiquitination protein BUL1P YML115C VAN1 vanadate resistance protein YML130C ERO1 required for protein disulfide bond formation in the ER YMR022W QRI8 E2 ubiquitin-conjugation enzyme YMR035W IMP2 mitochondrial inner membrane protease subunit YMR101C SRT1 cis-prenyltransferase homologue YMR149W SWP1 oligosaccharyltransferase delta subunit YMR150C IMP1 protease, mitochondrial YMR152W YIM1 mitochondrial inner membrane protease YMR154C RIM13 calpain-like cysteine protease YMR223W UBP8 similarity to mouse deubiquitinating enzyme and UBP13P,UBP9,DOA4P YMR246W FAA4 long-chain-fatty-acid--CoA ligase YMR274C RCE1 modulator of RAS2P YMR275C BUL1 ubiquitination pathway protein YNL021W HDA1 histone deacetylase A YNL029C KTR5 putative mannosyltransferase YNL048W ALG11 required for asparagine-linked glycosylation YNL172W APC1 subunit of anaphase-promoting complex (cyclosome) YNL186W UBP10 derepression of telomeric silencing YNL238W KEX2 endoproteinase of late golgi compartment YNR059W MNT4 similarity to to alpha-1,3-mannosyltransferase YOL141W PPM2 similarity to YDR435c and C.elegans hypothetical protein YOR002W ALG6 glucosyltransferase YOR023C AHC1 component of the ADA histone acetyltransferase complex YOR064C YNG1 component of histone acetyltransferase complex, has similarity to human retinoblastoma binding protein 2 YOR067C ALG8 glucosyltransferase YOR085W OST3 oligosaccharyltransferase gamma subunit YOR090C PTC5 putative 2C protein phosphatase (PP2Cs) YOR099W KTR1 mannosyltransferase involved in n-linked and o-linked glycosylation YOR103C OST2 oligosaccharyltransferase epsilon subunit YOR219C STE13 type IV dipeptidyl aminopeptidase YOR244W ESA1 histone acetyltransferase YOR249C APC5 component of the anaphase-promoting complex YOR321W PMT3 mannosyltransferase YOR339C UBC11 strong similarity to E2 ubiquitin-conjugating enzymes YOR370C MRS6 geranylgeranyltransferase regulatory subunit YPL001W HAT1 histone acetyltransferase subunit YPL003W ULA1 involved in protein modification YPL050C MNN9 required for complex N-glycosylation YPL051W ARL3 ADP-ribosylation factor-like protein, member of the arf-sar family in the ras superfamily YPL053C KTR6 mannosylphosphate transferase YPL059W GRX5 member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5) YPL086C ELP3 subunit of elongator/RNAPII holoenzyme with histone acetylase activity YPL148C PPT2 phosphopantetheine protein transferase YPL154C PEP4 aspartyl protease YPL227C ALG5 dolichol-P-glucose synthetase YPR051W MAK3 N-acetyltransferase YPR066W UBA3 ubiquitin-like protein activating enzyme YPR122W AXL1 protease YPR131C NAT3 N-acetyltransferases YPR176C BET2 geranylgeranyltransferase type II beta subunit YPR180W AOS1 forms together with UBA2P a heterodimeric activating enzyme for SMT3P YPR193C HPA2 Histone and other Protein Acetyltransferase modification with fatty acids (e.g. myristylation, palmitylation, farnesylation) (1 ORF) 06.07.01 1 YLR246W ERF2 protein involved in palmitoylation and localization of RAS2P modification with sugar residues (e.g. glycosylation) (2 ORFs) 06.07.02 2 YJL183W MNN11 related to MNN10P, and in a complex containing other MNN gene products YNL048W ALG11 required for asparagine-linked glycosylation modification by phosphorylation, dephosphorylation (6 ORFs) 06.07.03 6 YBR059C AKL1 Ark-family Kinase-Like protein YDR499W LCD1 cell cycle checkpoint protein YIL113W YIL113W strong similarity to dual-specificity phosphatase MSG5P YLL010C PSR1 plasma membrane phosphatase involved in sodium stress response YLR019W PSR2 plasma membrane phosphatase required for sodium stress response YOR090C PTC5 putative 2C protein phosphatase (PP2Cs) modification by acetylation, deacetylation (4 ORFs) 06.07.04 4 YLR410W VIP1 strong similarity to S. pombe protein ASP1P YOR023C AHC1 component of the ADA histone acetyltransferase complex YOR064C YNG1 component of histone acetyltransferase complex, has similarity to human retinoblastoma binding protein 2 YPR131C NAT3 N-acetyltransferases protein processing (proteolytic) (1 ORF) 06.07.11 1 YLL042C APG10 protein-conjugating enzyme essential for autophagy other protein modifications (6 ORFs) 06.07.99 6 YAL039C CYC3 holocytochrome-c synthase (cytochrome c heme lyase) YDR140W FYV9 similarity to probable methyltransferase S. pombe YDR435C PPM1 similarity to PPM2P and hypothetical C.elegans protein YHR109W CTM1 cytochrome c methyltransferase YIL008W URM1 ubiquitin related modifier YIL031W ULP2 SMT3P-specific protease, degrades conjugated ubiquitin-like protein SMT3P assembly of protein complexes (95 ORFs) 06.10 95 YBL007C SLA1 cytoskeleton assembly control protein YBL022C PIM1 ATP-dependent protease, mitochondrial YBL037W APL3 AP-2 complex subunit, alpha-adaptin, 113 KD YBR024W SCO2 involved in stability of COX1P and COX2P YBR037C SCO1 involved in stabilization of COX1P and COX2P YBR044C TCM62 chaperone required for assembly of mitochondrial succinate dehydrogenase YBR185C MBA1 respiratory chain assembly protein YBR195C MSI1 chromatin assembly complex, subunit p50 YBR227C MCX1 similarity to E.coli ATP-binding protein clpX YBR237W PRP5 pre-mRNA processing RNA-helicase YCL031C RRP7 involved in pre-rRNA processing and ribosome assembly YDL067C COX9 cytochrome-c oxidase chain VIIA YDL137W ARF2 GTP-binding protein of the ARF family YDL192W ARF1 small GTP-binding protein of the ARF family YDR079W PET100 cytochrome-c oxidase assembly protein YDR080W VPS41 required for the vacuolar assembly YDR162C NBP2 NAP1P-binding protein YDR265W PEX10 peroxisomal assembly protein - peroxin YDR322C-A TIM11 subunit E of the dimeric form of mitochondrial F1F0-ATPase YDR375C BCS1 mitochondrial protein of the CDC48/PAS1/SEC18 (AAA) family of ATPases YDR377W ATP17 ATP synthase complex, subunit f YDR389W SAC7 suppressor of actin mutation YDR460W TFB3 TFIIH subunit (transcription/repair factor) YDR473C PRP3 essential splicing factor YDR495C VPS3 vacuolar sorting protein YDR529C QCR7 ubiquinol--cytochrome-c reductase subunit 7 YER017C AFG3 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YER058W PET117 cytochrome c oxidase assembly factor YER141W COX15 cytochrome oxidase assembly factor YER154W OXA1 cytochrome oxidase biogenesis protein YGL119W ABC1 ubiquinol--cytochrome-c reductase complex assembly protein YGR062C COX18 required for activity of mitochondrial cytochrome oxidase YGR074W SMD1 snRNA-associated protein YGR105W VMA21 ATPase assembly integral membrane protein YGR133W PEX4 E2 ubiquitin-conjugating enzyme - peroxin YGR174C CBP4 ubiquinol--cytochrome-c reductase assembly factor YGR214W RPS0A 40S ribosomal protein p40 homolog A YGR241C YAP1802 Yeast Adaptor Protein, member of AP180 protein family YHR060W VMA22 vacuolar ATPase assembly protein YHR161C YAP1801 Yeast Adaptor Protein, member of AP180 protein family YIR006C PAN1 actin-cytoskeleton assembly protein YIR009W MSL1 U2 snRNA-associated protein with similarity to U2B YIR012W SQT1 suppresses dominant-negative mutants of the ribosomal protein QSR1 YJL180C ATP12 F1F0-ATPase complex assembly protein YJL203W PRP21 pre-mRNA splicing factor YJR005W APL1 AP-2 complex subunit, beta2-adaptin, 78 KD YJR034W PET191 involved in assembly of cytochrome oxidase YJR058C APS2 AP-2 complex subunit, sigma2 subunit, 17 KD YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL119C VPH2 H+-ATPase assembly protein YKL135C APL2 AP-1 complex subunit, beta1-adaptin, 82 KD YKL197C PEX1 peroxisomal assembly protein - peroxin YKR048C NAP1 nucleosome assembly protein I YLL008W DRS1 RNA helicase of the DEAD box family YLL009C COX17 interacts genetically with SCO1 and SCO2 in cytochrome oxidase assembly YLL039C UBI4 ubiquitin YLL050C COF1 cofilin, actin binding and severing protein YLR038C COX12 cytochrome-c oxidase, subunit VIB YLR048W RPS0B 40S ribosomal protein p40 homolog B YLR075W RPL10 60S large subunit ribosomal protein YLR093C NYV1 v-SNARE, vacuolar YLR144C ACF2 necessary for cortical actin assembly YLR170C APS1 AP-1 complex subunit, sigma1 subunit, 18 KD YLR327C YLR327C strong similarity to STF2P YLR393W ATP10 F1F0 ATPase complex assembly protein YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YML102W CAC2 chromatin assembly complex, subunit p60 YML129C COX14 cytochrome-c oxidase assembly protein YMR089C YTA12 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YMR256C COX7 cytochrome-c oxidase, subunit VII YNL233W BNI4 bud neck involved YNL243W SLA2 cytoskeleton assembly control protein YNL315C ATP11 F1F0-ATPase complex assembly protein YNL329C PEX6 peroxisomal assembly protein YNR038W DBP6 RNA helicase required for 60S ribosomal subunit assembly YOL144W NOP8 nucleolar protein required for 60S ribosome biogenesis YOR094W ARF3 ADP-ribosylation factor 3 YOR106W VAM3 syntaxin (t-SNARE) YOR134W BAG7 structural homolog of SAC7P YOR181W LAS17 component of actin cortical patches YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YPL085W SEC16 multidomain vesicle coat protein YPL132W COX11 cytochrome-c oxidase assembly protein YPL172C COX10 farnesyl transferase YPL213W LEA1 U2 A' snRNP protein YPL215W CBP3 required for assembly of cytochrome bc1 complex YPL231W FAS2 fatty-acyl-CoA synthase, alpha chain YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPR018W RLF2 chromatin assembly complex, subunit p90 YPR024W YME1 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YPR029C APL4 AP-1 complex subunit, gamma-adaptin, 94 KD YPR141C KAR3 kinesin-related protein YPR178W PRP4 U4/U6 snRNP 52 KD protein YPR191W QCR2 ubiquinol--cytochrome-c reductase 40KD chain II proteolytic degradation (160 ORFs) 06.13 160 YBL022C PIM1 ATP-dependent protease, mitochondrial YBL041W PRE7 20S proteasome subunit(beta6) YBL067C UBP13 ubiquitin carboxyl-terminal hydrolase YBL078C AUT7 essential for autophagy YBL084C CDC27 subunit of anaphase-promoting complex (cyclosome) YBR058C UBP14 ubiquitin specific protease YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR105C VID24 required for vacuolar import and degradation of FBP1P YBR128C APG14 required for autophagy YBR139W YBR139W strong similarity to carboxypeptidase YBR165W UBS1 positive regulator of CDC34P YBR173C UMP1 proteasome maturation factor YBR201W DER1 involved in degradation proteins in the ER YBR214W SDS24 strong similarity to hypothetical protein YGL056c YBR217W APG12 component of the autophagic system YBR227C MCX1 similarity to E.coli ATP-binding protein clpX YBR286W APE3 vacuolar aminopeptidase Y YCL008C STP22 required for vacuolar targeting of temperature-sensitive plasma membrane proteins, STE2P and CAN1P YCL057W PRD1 proteinase yscD YCR045C YCR045C similarity to serin proteases YDL007W RPT2 26S proteasome regulatory subunit YDL008W APC11 subunit of the anaphase promoting complex YDL020C RPN4 26S proteasome subunit YDL053C YDL053C hypothetical protein YDL064W UBC9 E2 ubiquitin-conjugating enzyme YDL077C VAM6 vacuolar carboxypeptidase Y YDL097C RPN6 subunit of the regulatory particle of the proteasome YDL122W UBP1 ubiquitin-specific protease YDL126C CDC48 microsomal protein of CDC48/PAS1/SEC18 family of ATPases YDL132W CDC53 controls G1/S transition YDL147W RPN5 subunit of the regulatory particle of the proteasome YDL190C UFD2 ubiquitin fusion degradation protein YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR069C DOA4 ubiquitin-specific protease YDR092W UBC13 E2 ubiquitin-conjugating enzyme YDR118W APC4 subunit of the anaphase promoting complex YDR144C MKC7 aspartyl protease of the periplasmic space YDR177W UBC1 E2 ubiquitin-conjugating enzyme YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR330W YDR330W similarity to hypothetical S. pombe protein YDR390C UBA2 E1-like (ubiquitin-activating) enzyme YDR394W RPT3 26S proteasome regulatory subunit YDR409W SIZ1 E3-like factor in the SUMO pathway YDR427W RPN9 subunit of the regulatory particle of the proteasome YEL060C PRB1 protease B, vacuolar YER012W PRE1 20S proteasome subunit C11(beta4) YER017C AFG3 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YER021W RPN3 26S proteasome regulatory subunit YER047C SAP1 member of the AAA-protein family YER078C YER078C similarity to E.coli X-Pro aminopeptidase II YER094C PUP3 20S proteasome subunit (beta3) YER098W UBP9 ubiquitin carboxyl-terminal hydrolase YER100W UBC6 E2 ubiquitin-conjugating enzyme YER125W RSP5 hect domain E3 ubiquitin-protein ligase YER144C UBP5 ubiquitin-specific protease YER151C UBP3 ubiquitin-specific proteinase YFR004W RPN11 26S proteasome regulatory subunit YFR006W YFR006W similarity to X-Pro dipeptidases YFR010W UBP6 ubiquitin-specific protease YFR036W CDC26 subunit of anaphase-promoting complex (cyclosome) YFR050C PRE4 20S proteasome subunit(beta7) YFR052W RPN12 26S proteasome regulatory subunit YGL003C CDH1 substrate-specific activator of APC-dependent proteolysis YGL011C SCL1 20S proteasome subunit YC7ALPHA/Y8 (alpha1) YGL017W ATE1 arginyl tRNA transferase YGL048C RPT6 26S proteasome regulatory subunit YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL116W CDC20 cell division control protein YGL180W APG1 essential for autophagocytosis YGL227W VID30 weak similarity to human RANBPM NP_005484.1 YGL240W DOC1 component of the anaphase promoting complex YGR048W UFD1 ubiquitin fusion degradation protein YGR135W PRE9 20S proteasome subunit Y13 (alpha3) YGR184C UBR1 ubiquitin-protein ligase YGR232W NAS6 possible homolog of human 26S proteasome regulatory subunit p28 YGR253C PUP2 20S proteasome subunit(alpha5) YGR270W YTA7 26S proteasome subunit YHR027C RPN1 26S proteasome regulatory subunit YHR028C DAP2 dipeptidyl aminopeptidase B YHR113W YHR113W similarity to vacuolar aminopeptidase Ape1p YHR166C CDC23 subunit of anaphase-promoting complex (cyclosome) YHR200W RPN10 26S proteasome regulatory subunit YIL015W BAR1 barrierpepsin precursor YIL031W ULP2 SMT3P-specific protease, degrades conjugated ubiquitin-like protein SMT3P YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL075C RPN2 26S proteasome regulatory subunit YIL137C YIL137C similarity to M.musculus aminopeptidase YIL148W RPL40A ubiquitin YIL156W UBP7 ubiquitin carboxy terminal hydrolase YJL001W PRE3 20S proteasome subunit (beta1) YJL036W SNX4 weak similarity to MVP1P YJL172W CPS1 Gly-X carboxypeptidase YSCS precursor YJL197W UBP12 ubiquitin C-terminal hydrolase YJR062C NTA1 amino-terminal amidase YJR099W YUH1 ubiquitin-specific protease YKL010C UFD4 similarity to rat ubiquitin ligase Nedd4 YKL022C CDC16 subunit of anaphase-promoting complex (cyclosome) YKL103C LAP4 aminopeptidase yscI precursor, vacuolar YKL145W RPT1 26S proteasome regulatory subunit YKL210W UBA1 E1-like (ubiquitin-activating) enzyme YKL213C DOA1 involved in ubiquitin-dependent proteolysis YKR038C YKR038C similarity to QRI7P YKR094C RPL40B ubiquitin YKR098C UBP11 ubiquitin C-terminal hydrolase YLL039C UBI4 ubiquitin YLR102C APC9 subunit of the Anaphase Promoting Complex YLR121C YPS3 GPI-anchored aspartyl protease 3 (yapsin 3) YLR127C APC2 component of the anaphase promoting complex YLR167W RPS31 ubiquitin/40S small subunit ribosomal protein YLR207W HRD3 involved in degradation of HMG2P YLR387C YLR387C similarity to YBR267w YLR423C APG17 protein involved in authophagy YLR452C SST2 involved in desensitization to alpha-factor pheromone YML088W UFO1 involved in degradation of HO protein YML092C PRE8 20S proteasome subunit Y7 (alpha2) YML111W BUL2 strong similarity to ubiquitination protein BUL1P YMR022W QRI8 E2 ubiquitin-conjugation enzyme YMR089C YTA12 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YMR159C APG16 coiled-coil protein required for autophagy YMR174C PAI3 protease A (ysca) inhibitor IA3 YMR223W UBP8 similarity to mouse deubiquitinating enzyme and UBP13P,UBP9,DOA4P YMR264W CUE1 involved in ubiquitination and degradation at the ER surface YMR275C BUL1 ubiquitination pathway protein YMR297W PRC1 carboxypeptidase y, serine-type protease YMR304W UBP15 similarity to human ubiquitin-specific protease YMR314W PRE5 20S proteasome subunit(alpha6) YNL015W PBI2 proteinase B inhibitor 2 YNL172W APC1 subunit of anaphase-promoting complex (cyclosome) YNL223W AUT2 essential for autophagy YNL239W LAP3 member of the GAL regulon YNR007C AUT1 essential for autophagocytosis YNR069C YNR069C similarity to central part of BUL1P YOL013C HRD1 involved in degradation of HMG2P YOL038W PRE6 20S proteasome subunit (alpha4) YOL111C YOL111C weak similarity to human ubiquitin-like protein GDX YOL153C YOL153C strong similarity to CPS1P YOR003W YSP3 subtilisin-like protease III YOR057W SGT1 suppressor of G2 allele of SKP1 YOR117W RPT5 26S proteasome regulatory subunit YOR123C LEO1 extremely hydrophilic protein YOR124C UBP2 ubiquitin-specific proteinase YOR157C PUP1 20S proteasome subunit (beta2) YOR249C APC5 component of the anaphase-promoting complex YOR259C RPT4 26S proteasome regulatory subunit YOR261C RPN8 26S proteasome regulatory subunit YOR339C UBC11 strong similarity to E2 ubiquitin-conjugating enzymes YOR362C PRE10 20S proteasome subunit C1 (alpha7) YPL020C ULP1 Ubl-specific protease YPL072W UBP16 weak similarity to UBP11P YPL074W YTA6 similarity to VPS4P and YER047c YPL096W PNG1 protein with de-N-glycosylation function YPL120W VPS30 involved in vacuolare protein sorting and autophagy YPL149W APG5 involved in autophagy and nutrient starvation YPL154C PEP4 aspartyl protease YPR024W YME1 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YPR103W PRE2 20S proteasome subunit (beta5) YPR108W RPN7 subunit of the regulatory particle of the proteasome YPR180W AOS1 forms together with UBA2P a heterodimeric activating enzyme for SMT3P YPR185W APG13 protein required for the autophagic process cytoplasmic and nuclear degradation (99 ORFs) 06.13.01 99 YBL041W PRE7 20S proteasome subunit(beta6) YBL084C CDC27 subunit of anaphase-promoting complex (cyclosome) YBR058C UBP14 ubiquitin specific protease YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR165W UBS1 positive regulator of CDC34P YBR173C UMP1 proteasome maturation factor YDL007W RPT2 26S proteasome regulatory subunit YDL008W APC11 subunit of the anaphase promoting complex YDL020C RPN4 26S proteasome subunit YDL064W UBC9 E2 ubiquitin-conjugating enzyme YDL097C RPN6 subunit of the regulatory particle of the proteasome YDL122W UBP1 ubiquitin-specific protease YDL126C CDC48 microsomal protein of CDC48/PAS1/SEC18 family of ATPases YDL132W CDC53 controls G1/S transition YDL147W RPN5 subunit of the regulatory particle of the proteasome YDL190C UFD2 ubiquitin fusion degradation protein YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR069C DOA4 ubiquitin-specific protease YDR092W UBC13 E2 ubiquitin-conjugating enzyme YDR118W APC4 subunit of the anaphase promoting complex YDR177W UBC1 E2 ubiquitin-conjugating enzyme YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR390C UBA2 E1-like (ubiquitin-activating) enzyme YDR394W RPT3 26S proteasome regulatory subunit YDR409W SIZ1 E3-like factor in the SUMO pathway YDR427W RPN9 subunit of the regulatory particle of the proteasome YER012W PRE1 20S proteasome subunit C11(beta4) YER021W RPN3 26S proteasome regulatory subunit YER094C PUP3 20S proteasome subunit (beta3) YER098W UBP9 ubiquitin carboxyl-terminal hydrolase YER100W UBC6 E2 ubiquitin-conjugating enzyme YER125W RSP5 hect domain E3 ubiquitin-protein ligase YER144C UBP5 ubiquitin-specific protease YER151C UBP3 ubiquitin-specific proteinase YFR004W RPN11 26S proteasome regulatory subunit YFR036W CDC26 subunit of anaphase-promoting complex (cyclosome) YFR050C PRE4 20S proteasome subunit(beta7) YFR052W RPN12 26S proteasome regulatory subunit YGL011C SCL1 20S proteasome subunit YC7ALPHA/Y8 (alpha1) YGL017W ATE1 arginyl tRNA transferase YGL048C RPT6 26S proteasome regulatory subunit YGL240W DOC1 component of the anaphase promoting complex YGR048W UFD1 ubiquitin fusion degradation protein YGR135W PRE9 20S proteasome subunit Y13 (alpha3) YGR184C UBR1 ubiquitin-protein ligase YGR232W NAS6 possible homolog of human 26S proteasome regulatory subunit p28 YGR253C PUP2 20S proteasome subunit(alpha5) YGR270W YTA7 26S proteasome subunit YHR027C RPN1 26S proteasome regulatory subunit YHR166C CDC23 subunit of anaphase-promoting complex (cyclosome) YHR200W RPN10 26S proteasome regulatory subunit YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL075C RPN2 26S proteasome regulatory subunit YIL148W RPL40A ubiquitin YIL156W UBP7 ubiquitin carboxy terminal hydrolase YJL001W PRE3 20S proteasome subunit (beta1) YJL197W UBP12 ubiquitin C-terminal hydrolase YJR062C NTA1 amino-terminal amidase YJR099W YUH1 ubiquitin-specific protease YKL010C UFD4 similarity to rat ubiquitin ligase Nedd4 YKL022C CDC16 subunit of anaphase-promoting complex (cyclosome) YKL145W RPT1 26S proteasome regulatory subunit YKL210W UBA1 E1-like (ubiquitin-activating) enzyme YKL213C DOA1 involved in ubiquitin-dependent proteolysis YKR094C RPL40B ubiquitin YKR098C UBP11 ubiquitin C-terminal hydrolase YLL039C UBI4 ubiquitin YLR102C APC9 subunit of the Anaphase Promoting Complex YLR121C YPS3 GPI-anchored aspartyl protease 3 (yapsin 3) YLR127C APC2 component of the anaphase promoting complex YLR167W RPS31 ubiquitin/40S small subunit ribosomal protein YLR452C SST2 involved in desensitization to alpha-factor pheromone YML088W UFO1 involved in degradation of HO protein YML092C PRE8 20S proteasome subunit Y7 (alpha2) YML111W BUL2 strong similarity to ubiquitination protein BUL1P YMR022W QRI8 E2 ubiquitin-conjugation enzyme YMR223W UBP8 similarity to mouse deubiquitinating enzyme and UBP13P,UBP9,DOA4P YMR275C BUL1 ubiquitination pathway protein YMR314W PRE5 20S proteasome subunit(alpha6) YNL172W APC1 subunit of anaphase-promoting complex (cyclosome) YNL239W LAP3 member of the GAL regulon YOL038W PRE6 20S proteasome subunit (alpha4) YOR057W SGT1 suppressor of G2 allele of SKP1 YOR117W RPT5 26S proteasome regulatory subunit YOR123C LEO1 extremely hydrophilic protein YOR124C UBP2 ubiquitin-specific proteinase YOR157C PUP1 20S proteasome subunit (beta2) YOR249C APC5 component of the anaphase-promoting complex YOR259C RPT4 26S proteasome regulatory subunit YOR261C RPN8 26S proteasome regulatory subunit YOR339C UBC11 strong similarity to E2 ubiquitin-conjugating enzymes YOR362C PRE10 20S proteasome subunit C1 (alpha7) YPL074W YTA6 similarity to VPS4P and YER047c YPL096W PNG1 protein with de-N-glycosylation function YPR103W PRE2 20S proteasome subunit (beta5) YPR108W RPN7 subunit of the regulatory particle of the proteasome YPR180W AOS1 forms together with UBA2P a heterodimeric activating enzyme for SMT3P YPR185W APG13 protein required for the autophagic process proteasomal degradation (1 ORF) 06.13.01.01 1 YOR123C LEO1 extremely hydrophilic protein lysosomal and vacuolar degradation (19 ORFs) 06.13.04 19 YBL078C AUT7 essential for autophagy YBR105C VID24 required for vacuolar import and degradation of FBP1P YBR217W APG12 component of the autophagic system YBR286W APE3 vacuolar aminopeptidase Y YCL008C STP22 required for vacuolar targeting of temperature-sensitive plasma membrane proteins, STE2P and CAN1P YDL077C VAM6 vacuolar carboxypeptidase Y YEL060C PRB1 protease B, vacuolar YGL180W APG1 essential for autophagocytosis YGL227W VID30 weak similarity to human RANBPM NP_005484.1 YHR028C DAP2 dipeptidyl aminopeptidase B YJL172W CPS1 Gly-X carboxypeptidase YSCS precursor YKL103C LAP4 aminopeptidase yscI precursor, vacuolar YMR159C APG16 coiled-coil protein required for autophagy YMR297W PRC1 carboxypeptidase y, serine-type protease YNL223W AUT2 essential for autophagy YNR007C AUT1 essential for autophagocytosis YOR003W YSP3 subtilisin-like protease III YPL149W APG5 involved in autophagy and nutrient starvation YPL154C PEP4 aspartyl protease vacuolar degradation (1 ORF) 06.13.04.02 1 YGL227W VID30 weak similarity to human RANBPM NP_005484.1 other proteolytic degradation (15 ORFs) 06.13.99 15 YBL022C PIM1 ATP-dependent protease, mitochondrial YBR128C APG14 required for autophagy YBR201W DER1 involved in degradation proteins in the ER YCL057W PRD1 proteinase yscD YDR144C MKC7 aspartyl protease of the periplasmic space YER017C AFG3 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YFR006W YFR006W similarity to X-Pro dipeptidases YHR113W YHR113W similarity to vacuolar aminopeptidase Ape1p YIL015W BAR1 barrierpepsin precursor YIL031W ULP2 SMT3P-specific protease, degrades conjugated ubiquitin-like protein SMT3P YMR089C YTA12 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YMR264W CUE1 involved in ubiquitination and degradation at the ER surface YOL153C YOL153C strong similarity to CPS1P YPL120W VPS30 involved in vacuolare protein sorting and autophagy YPR024W YME1 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) other protein fate related activities (8 ORFs) 06.99 8 YDL104C QRI7 similarity to H.influenzae sialoglycoprotease (gcp) YDL184W-A PI-SCEI homing endonuclease with protein splicing activity YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDR258C HSP78 heat shock protein of clpb family of ATP-dependent proteases, mitochondrial YDR415C YDR415C strong similarity to bacterial leucyl aminopeptidase YLL026W HSP104 heat shock protein YLR002C NOC3 required for maturation and intranuclear transport of pre-ribosomes YMR038C LYS7 copper chaperone for superoxide dismutase SOD1P CELLULAR TRANSPORT AND TRANSPORT MECHANISMS (495 ORFs) 08 495 YAL002W VPS8 vacuolar sorting protein, 134 kD YAL005C SSA1 heat shock protein of HSP70 family, cytosolic YAL007C ERP2 p24 protein involved in membrane trafficking YAL026C DRS2 P-type amino-phospholipids-ATPase YAL029C MYO4 myosin heavy chain, unconventional (class V) isoform YAL030W SNC1 synaptic vesicle-associated membrane protein YAL042W ERV46 component of copii vesicles involved in transport between the ER and golgi complex YAL048C YAL048C vacuolar aspartic proteasse YAL055W PEX22 peroxisomal matrix protein import YAR002C-A ERP1 p24 protein involved in membrane trafficking YAR002W NUP60 nuclear pore protein YAR035W YAT1 carnitine acetyltransferase, mitochondrial YBL017C PEP1 vacuolar protein sorting/targeting protein YBL030C PET9 ADP/ATP carrier protein (MCF) YBL037W APL3 AP-2 complex subunit, alpha-adaptin, 113 KD YBL040C ERD2 ER lumen protein-retaining receptor YBL050W SEC17 transport vesicle fusion protein YBL063W KIP1 kinesin-related protein YBL078C AUT7 essential for autophagy YBL079W NUP170 nuclear pore protein YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBL106C SRO77 polarized exocytosis by regulating SNARE function YBR017C KAP104 beta-karyopherin YBR021W FUR4 uracil permease YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR068C BAP2 leucine permease, high-affinity (S1) YBR069C TAT1 amino acid permease YBR080C SEC18 vesicular-fusion protein, functional homolog of NSF YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR085W AAC3 ADP/ATP carrier protein (MCF) YBR091C MRS5 subunit of the TIM22-complex YBR097W VPS15 ser/thr protein kinase YBR102C EXO84 exocyst protein essential for secretion YBR104W YMC2 mitochondrial carrier protein (MCF) YBR105C VID24 required for vacuolar import and degradation of FBP1P YBR109C CMD1 calmodulin YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YBR162W-A YSY6 secretory pathway protein YBR164C ARL1 ADP-ribosylation factor YBR170C NPL4 nuclear protein localization factor and ER translocation component YBR171W SEC66 ER protein-translocation complex subunit YBR172C SMY2 kinesin-related protein YBR192W RIM2 mitochondrial carrier protein (MCF) YBR254C TRS20 TRAPP subunit of 20 kDa involved in targeting and fusion of ER to golgi transport vesicles YBR264C YPT10 similarity to GTP-binding proteins YBR288C APM3 AP-3 complex subunit, mu3 subunit, 55 KD YBR291C CTP1 citrate transport protein, mitochondrial (MCF) YBR294W SUL1 high-affinity sulfate transport protein YBR298C MAL31 maltose permease YCL008C STP22 required for vacuolar targeting of temperature-sensitive plasma membrane proteins, STE2P and CAN1P YCL040W GLK1 aldohexose specific glucokinase YCR009C RVS161 similarity to human amphiphysin and RVS167P YCR032W BPH1 similarity to human beige-like protein and mouse lysosomal trafficking regulator YCR067C SED4 protein of the endoplasmic reticulum YCR075C ERS1 intracellular protein transport protein YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL018C ERP3 weak similarity to DEP1P YDL029W ARP2 actin-like protein YDL058W USO1 intracellular protein transport protein YDL116W NUP84 nuclear pore protein YDL119C YDL119C similarity to bovine Graves disease carrier protein YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDL137W ARF2 GTP-binding protein of the ARF family YDL145C COP1 coatomer complex alpha chain of secretory pathway vesicles YDL161W ENT1 clathrin binding protein, required for endocytosis YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL192W ARF1 small GTP-binding protein of the ARF family YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL195W SEC31 component of the COPII coat of ER-golgi vesicles YDL198C YHM1 member of the mitochondrial carrier family (MCF) YDL207W GLE1 RNA export mediator YDL210W UGA4 GABA-specific high-affinity permease YDL217C TIM22 subunit of the TIM22-complex YDL226C GCS1 ADP-ribosylation factor GTPase-activating protein (ARF-GAP) YDR002W YRB1 ran-specific GTPase-activating protein YDR027C LUV1 interacts with the beta-tubulin binding protein RBL2P YDR040C ENA1 P-type ATPase involved in Na+ and Li+ efflux YDR046C BAP3 valine transporter YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR086C SSS1 ER protein-translocase complex subunit YDR107C YDR107C strong similarity to EMP70 protein YDR108W GSG1 sporulation specific protein YDR117C YDR117C similarity to mouse ligatin, a trafficking receptor for phosphoglycoproteins YDR129C SAC6 actin filament bundling protein, fimbrin YDR135C YCF1 glutathione S-conjugate transporter, vacuolar YDR142C PEX7 peroxisomal import protein - peroxin YDR164C SEC1 protein transport protein YDR166C SEC5 required for exocytosis YDR170C SEC7 component of non-clathrin vesicle coat YDR177W UBC1 E2 ubiquitin-conjugating enzyme YDR189W SLY1 hydrophilic suppressor of YPT1 and member of the SEC1P family YDR192C NUP42 nuclear pore protein YDR238C SEC26 coatomer complex beta chain of secretory pathway vesicles YDR244W PEX5 peroxisomal targeting signal receptor YDR246W TRS23 TRAPP subunit of 20 kDa involved in targeting and fusion of ER to golgi transport vesicles YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR299W BFR2 involved in protein transport steps at the Brefeldin A blocks YDR320C SWA2 clathrin-binding protein required for normal clathrin function and for uncoating of clathrin-coated vesicles YDR322C-A TIM11 subunit E of the dimeric form of mitochondrial F1F0-ATPase YDR323C PEP7 vacuolar segregation protein YDR329C PEX3 peroxisomal assembly protein - peroxin YDR335W MSN5 multicopy supressor of SNF1 mutation YDR342C HXT7 high-affinity hexose transporter YDR343C HXT6 high-affinity hexose transporter YDR345C HXT3 low-affinity hexose transporter YDR395W SXM1 putative beta-karyopherin YDR407C TRS120 TRAPP subunit of 120 kDa involved in targeting and fusion of ER to golgi transport vesicles YDR424C DYN2 dynein light chain 1, cytosolic YDR432W NPL3 nucleolar protein YDR456W NHX1 NA+-H+ antiporter YDR468C TLG1 member of the syntaxin family of t-SNAREs YDR472W TRS31 TRAPP subunit of 31 kDa involved in targeting and fusion of ER to golgi transport vesicles YDR484W SAC2 suppressor of actin mutation YDR488C PAC11 required in the absence of CIN8P YDR497C ITR1 myo-inositol permease, major YDR498C SEC20 secretory pathway protein YEL006W YEL006W similarity to peroxisomal membrane and mitochondrial carrier proteins YEL020W-A TIM9 essential subunit of the TIM22-complex for mitochondrial protein import YEL022W GEA2 GDP/GTP exchange factor for ARF YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YEL059C-A SOM1 required for mitochondrial IMP1 peptidase function YEL061C CIN8 kinesin-related protein YEL063C CAN1 amino acid permease YEL069C HXT13 high-affinity hexose transporter YER006W YER006W similarity to P.polycephalum myosin-related protein mlpA YER008C SEC3 component of exocyst complex YER009W NTF2 nuclear transport factor YER015W FAA2 long-chain-fatty-acid--CoA ligase YER019C-A SBH2 ER protein-translocation complex subunit YER024W YAT2 carnitine O-acetyltransferase YER031C YPT31 GTP-binding protein of the rab family YER039C HVG1 strong similarity to vanadate resistance protein GOG5P YER053C YER053C strong similarity to mitochondrial phosphate carrier protein YER056C FCY2 purine-cytosine permease YER060W FCY21 purine-cytosine permease YER060W-A FCY22 purine/cytosine permease with similarity to FCY2P YER087C-B SBH1 involved in translocation into the ER YER105C NUP157 nuclear pore protein YER107C GLE2 required for nuclear pore complex structure and function YER110C KAP123 RAN-binding protein YER136W GDI1 GDP dissociation inhibitor YER157W SEC34 required for vesicle tethering to the yeast Golgi apparatus YFL005W SEC4 GTP-binding protein of the ras superfamily YFL011W HXT10 hexose transporter YFL025C BST1 negative regulator of COPII vesicle formation YFL038C YPT1 GTP-binding protein of the rab family YFL039C ACT1 actin YFL041W FET5 multicopy oxidase YFL050C ALR2 divalent cation transprter YFR002W NIC96 nuclear pore protein YFR019W FAB1 phosphatidylinositol 3-phosphate 5-kinase YFR051C RET2 coatomer complex delta chain YGL002W ERP6 strong similarity to human gp25L2 protein YGL006W PMC1 Ca2+-transporting P-type ATPase YGL016W KAP122 Member of the karyopherin-beta family, nuclear import YGL054C ERV14 ER-derived Vesicles YGL077C HNM1 choline permease YGL092W NUP145 nuclear pore protein YGL095C VPS45 vacuolar protein sorting-associated protein YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL100W SEH1 nuclear pore protein YGL137W SEC27 coatomer complex beta' chain (beta'-cop) of secretory pathway vesicles YGL145W TIP20 required for ER to Golgi transport YGL153W PEX14 peroxisomal protein involved in protein import - peroxin YGL167C PMR1 Ca2+-transporting P-type ATPase YGL172W NUP49 nuclear pore protein YGL180W APG1 essential for autophagocytosis YGL200C EMP24 component of the COPII-coated vesicles, 24 kDa YGL206C CHC1 clathrin heavy chain YGL210W YPT32 small GTP-binding protein essential for Golgi function YGL212W VAM7 vacuolar morphogenesis protein YGL216W KIP3 kinesin-related protein required for nuclear migration YGL225W GOG5 GDP-mannose transporter into the lumen of the Golgi YGL233W SEC15 vesicular traffic control protein YGL238W CSE1 importin-beta-like protein YGL241W KAP114 Member of the karyopherin-beta family, nuclear import YGR009C SEC9 protein transport protein YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YGR028W MSP1 intra-mitochondrial sorting protein YGR055W MUP1 high affinity methionine permease YGR057C LST7 required for amino acid permease transport from the Golgi to the cell surface YGR082W TOM20 mitochondrial outer membrane import receptor subunit, 20 kD YGR096W YGR096W hypothetical mitochondrial transport protein YGR119C NUP57 nuclear pore protein YGR120C SEC35 required for ER to golgi vesicle docking YGR121C MEP1 ammonia permease of high capacity and moderate affinity YGR131W YGR131W strong similarity to Nce2p YGR166W KRE11 beta-glucan synthesis-associated protein YGR167W CLC1 clathrin light chain YGR172C YIP1 golgi membrane protein YGR191W HIP1 histidine permease YGR218W CRM1 nuclear export factor, exportin YGR239C PEX21 peroxin, essential for peroxisomal targeting by the PTS2 pathway YGR241C YAP1802 Yeast Adaptor Protein, member of AP180 protein family YGR257C YGR257C similarity to C.elegans C16C10.1 YGR261C APL6 AP-3 complex subunit, beta3-adaptin, 91 KD YHL019C APM2 involved in clathrin-independent transport processes YHL031C GOS1 SNARE protein of Golgi compartment YHL036W MUP3 very low affinity methionine permease YHR002W YHR002W similarity to bovine mitochondrial carrier protein/Grave's disease carrier protein YHR005C-A MRS11 subunit of the TIM22-complex YHR012W VPS29 involved in vacuolar protein sorting YHR023W MYO1 myosin-1 isoform (type II myosin) heavy chain YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YHR050W SMF2 probable manganese transporter YHR092C HXT4 moderate- to low-affinity glucose transporter YHR094C HXT1 low-affinity hexose transporter YHR096C HXT5 member of the hexose transporter family YHR108W GGA2 Arf-binding protein YHR110W ERP5 similarity to human gp25L2 protein YHR117W TOM71 protein with similarity to TOM70P/Mas70p YHR123W EPT1 sn-1,2-diacylglycerol ethanolamine- and cholinephosphotransferase YHR127W HSN1 hypothetical protein YHR129C ARP1 centractin YHR135C YCK1 casein kinase I isoform YHR142W CHS7 control of protein export from the ER (like chitin synthase III) YHR156C YHR156C weak similarity to mouse kinesin KIF3B YHR160C PEX18 peroxin, essential for peroxisomal targeting by the PTS2 pathway YHR161C YAP1801 Yeast Adaptor Protein, member of AP180 protein family YHR175W CTR2 copper transport protein YHR195W NVJ1 part of nucleus-vacuole junctions YIL004C BET1 protein transport protein YIL006W YIL006W similarity to FLX1P YIL022W TIM44 mitochondrial inner membrane import receptor subunit YIL062C ARC15 subunit of the ARP2/3 complex YIL063C YRB2 involved in nuclear protein export YIL068C SEC6 protein transport protein YIL076W SEC28 epsilon-COP coatomer subunit YIL109C SEC24 component of COPII coat of ER-Golgi vesicles YIL114C POR2 voltage dependent anion channel (YVDAC2) YIL115C NUP159 nuclear pore protein YIL134W FLX1 FAD carrier protein (MCF), mitochondrial YIL149C MLP2 involved in translocation of macromolecules between the nucleoplasm and the NPC YIL170W HXT12 strong similarity to sugar transport proteins YIR004W DJP1 DnaJ-like protein involved specifically in peroxisomal protein import YIR006C PAN1 actin-cytoskeleton assembly protein YIR011C STS1 required for transport of RNA15P from the cytoplasm to the nucleus YIR028W DAL4 allantoin permease YJL004C SYS1 multi copy suppressor of YPT6 YJL024C APS3 AP-3 complex subunit, sigma3 subunit, 22 KD YJL029C VPS53 subunit of VP52-54 complex, required for protein sorting at the yeast late Golgi YJL034W KAR2 nuclear fusion protein YJL039C NUP192 nucleoporin localize at the inner site of the nuclear membrane YJL041W NSP1 nuclear pore protein YJL044C GYP6 GTPase-activating protein YJL050W MTR4 involved in nucleocytoplasmic transport of mRNA YJL054W TIM54 translocase for the insertion of proteins into the mitochondrial inner membrane YJL061W NUP82 nuclear pore protein YJL085W EXO70 70 kDa exocyst component protein YJL093C TOK1 outward-rectifier potassium channel YJL099W CHS6 chitin biosynthesis protein YJL129C TRK1 potassium transport protein TRK1P, high-affinity YJL133W MRS3 RNA splicing protein and member of the mitochondrial carrier family (MCF) YJL143W TIM17 mitochondrial inner membrane import translocase subunit YJL154C VPS35 protein-sorting protein, vacuolar YJL193W YJL193W similarity to SLY41P YJL205C-A NCE101 involved in non-classical protein export pathway YJL210W PEX2 peroxisomal assembly protein - peroxin YJL214W HXT8 hexose transport protein YJL219W HXT9 hexose transport protein YJL222W VTH2 strong similarity to PEP1P YJR005W APL1 AP-2 complex subunit, beta2-adaptin, 78 KD YJR031C GEA1 GDP/GTP exchange factor for ARF YJR040W GEF1 voltage-gated chloride channel protein YJR042W NUP85 nuclear pore protein YJR045C SSC1 mitochondrial heat shock protein 70-related protein YJR058C APS2 AP-2 complex subunit, sigma2 subunit, 17 KD YJR059W PTK2 involved in polyamine uptake YJR065C ARP3 actin related protein YJR074W MOG1 GSP1-interacting protein YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR095W SFC1 succinate-fumarate transporter YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YJR135W-A TIM8 delivers Proteins across the intermembrane space of mitochondria to the TIM22 complex YJR152W DAL5 allantoate permease YJR158W HXT16 member of the hexose transporter family of the major facilitator superfamily [MFS] YKL002W DID4 class E vacuolar-protein sorting and endocytosis factor YKL006C-A SFT1 SNARE-like protein YKL013C ARC19 subunit of the ARP2/3 complex YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL041W VPS24 endosomal Vps protein complex subunit YKL057C NUP120 nuclear pore protein YKL068W NUP100 nuclear pore protein YKL079W SMY1 kinesin-related protein YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL120W OAC1 similarity to mitochondrial uncoupling proteins (MCF) YKL129C MYO3 myosin type I YKL135C APL2 AP-1 complex subunit, beta1-adaptin, 82 KD YKL175W ZRT3 vacuolar membrane protein involved in the regulation of zinc storage YKL186C MTR2 mRNA transport protein YKL188C PXA2 ABC transporter, peroxisomal YKL196C YKT6 SNARE protein for Endoplasmic Reticulum-Golgi transport YKL198C PTK1 polyamine transport enhancing protein YKL199C YKT9 PTK1-YKT9 overlapping sequences may arise from a gene duplication event involving chromosomes X and XI YKL209C STE6 ATP-binding cassette transporter protein YKL212W SAC1 recessive suppressor of secretory defect YKR014C YPT52 GTP-binding protein of the rab family YKR035W-A DID2 class E vacuolar-protein sorting and endocytosis factor YKR039W GAP1 general amino acid permease YKR050W TRK2 moderate-affinity potassium transport protein YKR052C MRS4 RNA splicing protein and member of the mitochondrial carrier family (MCF) YKR054C DYN1 dynein heavy chain, cytosolic YKR068C BET3 involved in targeting and fusion of ER to golgi transport vesicles YKR082W NUP133 nuclear pore protein YKR093W PTR2 peptide transporter YLL024C SSA2 heat shock protein of HSP70 family, cytosolic YLL043W FPS1 glycerol channel protein YLL050C COF1 cofilin, actin binding and severing protein YLR018C POM34 component of nuclear pore complex (nucleoporin) YLR025W SNF7 class E Vps protein YLR026C SED5 syntaxin (T-SNARE) YLR078C BOS1 secretory pathway protein YLR081W GAL2 galactose (and glucose) permease YLR083C EMP70 endosomal protein YLR088W GAA1 required for attachment of GPI anchor onto proteins YLR119W SRN2 suppressor of RNA1-1 mutation YLR148W PEP3 vacuolar membrane protein YLR166C SEC10 required for exocytosis YLR170C APS1 AP-1 complex subunit, sigma1 subunit, 18 KD YLR191W PEX13 peroxisomal protein involved in protein import - peroxin YLR206W ENT2 clathrin binding protein, required for endocytosis YLR208W SEC13 protein transport protein YLR240W VPS34 phosphatidylinositol 3-kinase YLR250W SSP120 secretory protein YLR262C YPT6 GTP-binding protein of the rab family YLR268W SEC22 synaptobrevin (V-SNARE) YLR292C SEC72 ER protein-translocation complex subunit YLR293C GSP1 GTP-binding protein of the ras superfamily YLR295C ATP14 F1F0-ATPase complex, subunit h YLR309C IMH1 involved in vesicular transport YLR335W NUP2 nuclear pore protein YLR337C VRP1 verprolin YLR347C KAP95 karyopherin-beta YLR348C DIC1 dicarboxylate carrier protein YLR370C ARC18 subunit of the ARP2/3 complex YLR378C SEC61 ER protein-translocation complex subunit YLR396C VPS33 vacuolar sorting protein YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YML001W YPT7 GTP-binding protein of the RAB family YML012W ERV25 component of the COPII-coated vesicles, 25 Kda YML042W CAT2 carnitine O-acetyltransferase YML049C RSE1 involved in RNA splicing and ER to Golgi transport YML062C MFT1 mitochondrial fusion target protein YML067C ERV41 component of copii vesicles involved in transport between the ER and golgi complex YML077W BET5 involved in targeting and fusion of ER to golgi transport vesicles YML097C VPS9 vacuolar sorting protein YML103C NUP188 nuclear pore protein YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YMR004W MVP1 required for vacuolar protein sorting YMR011W HXT2 high-affinity hexose transporter YMR017W SPO20 DBF2P interacting protein YMR047C NUP116 nuclear pore protein YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YMR056C AAC1 ADP/ATP carrier protein (MCF) YMR058W FET3 cell surface ferroxidase, high affinity YMR060C TOM37 mitochondrial outer membrane import receptor subunit, 37 kD YMR079W SEC14 phosphatidylinositol(PI)/phosphatidylcholine(PC) transfer protein YMR109W MYO5 myosin I YMR129W POM152 nuclear pore membrane glycoprotein YMR153W NUP53 component of the karyopherin docking complex of the nuclear pore complex YMR166C YMR166C similarity to members of the mitochondrial carrier protein family YMR183C SSO2 syntaxin (T-SNARE) YMR197C VTI1 v-SNARE: involved in Golgi retrograde protein traffic YMR198W CIK1 spindle pole body associated protein YMR203W TOM40 forms the hydrophilic channel of the mitochondrial import pore for preproteins YMR218C TRS130 TRAPP subunit of 130 kDa involved in targeting and fusion of ER to golgi transport vesicles YMR231W PEP5 vacuolar biogenesis protein YMR243C ZRC1 zinc- and cadmium resistance protein YMR255W GFD1 protein of the nuclear pore complex YMR294W JNM1 mitosis protein, involved in nuclear migration YMR301C ATM1 ATP-binding cassette transporter protein, mitochondrial YMR308C PSE1 beta karyopherin YMR319C FET4 low affinity Fe(II) iron transport protein YNL003C PET8 member of the mitochondrial carrier (MCF) family YNL006W LST8 required for transport of permeases from the golgi to the plasma membrane YNL036W NCE103 involved in non-classical protein export pathway YNL044W YIP3 protein of unknown function YNL055C POR1 mitochondrial outer membrane porin YNL064C YDJ1 mitochondrial and ER import protein YNL070W TOM7 mitochondrial outer membrane import receptor subunit, 7 kD YNL079C TPM1 tropomyosin 1 YNL083W YNL083W weak similarity to rabbit peroxisomal Ca-dependent solute carrier YNL084C END3 required for endocytosis and cytoskeletal organization YNL093W YPT53 GTP-binding protein of the RAB family (RAS superfamily) YNL121C TOM70 mitochondrial outer membrane specialized import receptor YNL131W TOM22 mitochondrial outer membrane import receptor complex subunit YNL142W MEP2 high affinity low capacity ammonia permease YNL154C YCK2 casein kinase I isoform YNL183C NPR1 ser/thr protein kinase YNL189W SRP1 karyopherin-alpha or importin YNL214W PEX17 component of the peroxisomal protein translocation - peroxin YNL223W AUT2 essential for autophagy YNL243W SLA2 cytoskeleton assembly control protein YNL263C YIF1 SLH1P Interacting Factor YNL268W LYP1 lysine-specific high-affinity permease YNL270C ALP1 high-affinity permease for basic amino acids YNL272C SEC2 protein transport protein YNL287W SEC21 coatomer complex gamma chain (gamma-COP) of secretory pathway vesicles YNL304W YPT11 similarity to YPT1P and rab GTP-binding proteins YNL318C HXT14 hexose transport protein YNL325C FIG4 weak similarity to inositol phosphatase YNR006W VPS27 vacuolar protein sorting-associated protein YNR007C AUT1 essential for autophagocytosis YNR017W MAS6 mitochondrial inner membrane import translocase subunit YNR026C SEC12 GDP/GTP exchange factor for SAR1P YNR035C ARC35 subunit of the ARP2/3 complex YNR049C MSO1 secretion protein, multicopy suppressor of SEC1 YNR072W HXT17 sugar transport protein YOL018C TLG2 member of the syntaxin family of t-SNAREs YOL020W TAT2 high affinity tryptophan transport protein YOL044W PEX15 required for peroxisome assembly - peroxin YOL062C APM4 AP-2 complex subunit, mu2 subunit, 55 KD YOL077W-A ATP19 subunit K of the dimeric form of mitochondrial F1F0-ATP synthase YOL103W ITR2 myo-inositol permease, minor YOL122C SMF1 manganese transporter YOL130W ALR1 divalent cation transporter YOL156W HXT11 low affinity glucose transport protein YOR034C AKR2 involved in constitutive endocytosis of STE3P YOR035C SHE4 required for mother cell-specific gene expression YOR036W PEP12 syntaxin (T-SNARE), vacuolar YOR037W CYC2 cytochrome-c mitochondrial import factor YOR045W TOM6 mitochondrial outer membrane import receptor subunit, 6 kD YOR048C RAT1 5'-3' exoribonuclease YOR070C GYP1 GTPase activating protein for YPT1P and SEC4P YOR075W UFE1 syntaxin (T-SNARE) of the ER YOR089C VPS21 GTP-binding protein YOR094W ARF3 ADP-ribosylation factor 3 YOR098C NUP1 nuclear pore protein YOR100C CRC1 mitochondrial carnitine carrier, member of the mitochondrial carrier (MCF) family YOR106W VAM3 syntaxin (t-SNARE) YOR115C TRS33 TRAPP subunit of 33 kDa involved in targeting and fusion of ER to golgi transport vesicles YOR130C ORT1 ornithine transport protein of mitochondria involved in arginine metabolism, member of the mitochondrial carrier family (MCF) YOR160W MTR10 involved in nuclear protein import YOR185C GSP2 GTP-binding protein of the RAS superfamily YOR206W NOC2 crucial for intranuclear movement of ribosomal precursor particles YOR216C RUD3 suppressor of USO1-1 transport defect YOR222W ODC2 similarity to ADP/ATP carrier proteins YOR232W MGE1 heat shock protein - chaperone YOR254C SEC63 ER protein-translocation complex subunit YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR307C SLY41 secretory pathway protein YOR316C COT1 cobalt accumulation protein YOR326W MYO2 myosin heavy chain YOR327C SNC2 synaptobrevin (v-SNARE) homolog present on post-Golgi vesicles YOR329C SCD5 suppressor of clathrin deficiency YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YOR348C PUT4 proline and gamma-aminobutyrate permease YPL010W RET3 coatomer complex zeta chain YPL019C VTC3 strong similarity to YFL004w, similarity to YJL012c YPL045W VPS16 vacuolar sorting protein YPL051W ARL3 ADP-ribosylation factor-like protein, member of the arf-sar family in the ras superfamily YPL065W VPS28 involved in vacuolar traffic YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL085W SEC16 multidomain vesicle coat protein YPL094C SEC62 ER protein-translocation complex subunit YPL120W VPS30 involved in vacuolare protein sorting and autophagy YPL124W NIP29 nuclear import protein YPL125W KAP120 nuclear transport factor, member of karyopherin-beta family YPL134C ODC1 similarity to ADP,ATP carrier proteins YPL145C KES1 involved in ergosterol biosynthesis YPL147W PXA1 long-chain fatty acid transporter YPL155C KIP2 kinesin-related protein YPL174C NIP100 component of the dynactin complex YPL195W APL5 AP-3 complex subunit, gamma-adaptin, 107 KD YPL218W SAR1 GTP-binding protein of the ARF family YPL224C MMT2 mitochondrial iron transporter YPL232W SSO1 syntaxin-related protein YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPL259C APM1 AP-1 complex subunit, mu1 subunit, 54 KD YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPR009W YPR009W similarity to sterol uptake protein SUT1P YPR011C YPR011C similarity to ADP/ATP carrier proteins and Graves disease carrier protein YPR017C DSS4 GDP/GTP exchange factor for SEC4P YPR021C YPR021C similarity to human citrate transporter protein YPR028W YIP2 Ypt-interacting protein YPR029C APL4 AP-1 complex subunit, gamma-adaptin, 94 KD YPR032W SRO7 polarized exocytosis by regulating SNARE function YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar YPR055W SEC8 protein transport protein YPR058W YMC1 mitochondrial carrier protein (MCF) YPR095C SYT1 guanine nucleotide exchange factor, contains a conserved SEC7P-domain YPR124W CTR1 copper transport protein YPR129W SCD6 suppressor of clathrin deficiency YPR133W-A TOM5 mitochondrial outer membrane protein YPR141C KAR3 kinesin-related protein YPR149W NCE102 involved in non-classical protein export pathway YPR173C VPS4 vacuolar sorting protein YPR181C SEC23 component of COPII coat of ER-golgi vesicles YPR185W APG13 protein required for the autophagic process Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 nuclear transport (59 ORFs) 08.01 59 YAL005C SSA1 heat shock protein of HSP70 family, cytosolic YAR002W NUP60 nuclear pore protein YBL079W NUP170 nuclear pore protein YBR017C KAP104 beta-karyopherin YBR170C NPL4 nuclear protein localization factor and ER translocation component YDL116W NUP84 nuclear pore protein YDL207W GLE1 RNA export mediator YDR002W YRB1 ran-specific GTPase-activating protein YDR192C NUP42 nuclear pore protein YDR335W MSN5 multicopy supressor of SNF1 mutation YDR395W SXM1 putative beta-karyopherin YDR432W NPL3 nucleolar protein YER009W NTF2 nuclear transport factor YER105C NUP157 nuclear pore protein YER107C GLE2 required for nuclear pore complex structure and function YER110C KAP123 RAN-binding protein YFR002W NIC96 nuclear pore protein YGL016W KAP122 Member of the karyopherin-beta family, nuclear import YGL092W NUP145 nuclear pore protein YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL100W SEH1 nuclear pore protein YGL172W NUP49 nuclear pore protein YGL238W CSE1 importin-beta-like protein YGL241W KAP114 Member of the karyopherin-beta family, nuclear import YGR119C NUP57 nuclear pore protein YGR218W CRM1 nuclear export factor, exportin YIL063C YRB2 involved in nuclear protein export YIL115C NUP159 nuclear pore protein YIL149C MLP2 involved in translocation of macromolecules between the nucleoplasm and the NPC YIR011C STS1 required for transport of RNA15P from the cytoplasm to the nucleus YJL039C NUP192 nucleoporin localize at the inner site of the nuclear membrane YJL041W NSP1 nuclear pore protein YJL050W MTR4 involved in nucleocytoplasmic transport of mRNA YJL061W NUP82 nuclear pore protein YJR042W NUP85 nuclear pore protein YJR074W MOG1 GSP1-interacting protein YKL057C NUP120 nuclear pore protein YKL068W NUP100 nuclear pore protein YKL186C MTR2 mRNA transport protein YKR082W NUP133 nuclear pore protein YLR018C POM34 component of nuclear pore complex (nucleoporin) YLR119W SRN2 suppressor of RNA1-1 mutation YLR293C GSP1 GTP-binding protein of the ras superfamily YLR335W NUP2 nuclear pore protein YLR347C KAP95 karyopherin-beta YML103C NUP188 nuclear pore protein YMR047C NUP116 nuclear pore protein YMR129W POM152 nuclear pore membrane glycoprotein YMR153W NUP53 component of the karyopherin docking complex of the nuclear pore complex YMR255W GFD1 protein of the nuclear pore complex YMR308C PSE1 beta karyopherin YNL189W SRP1 karyopherin-alpha or importin YOR048C RAT1 5'-3' exoribonuclease YOR098C NUP1 nuclear pore protein YOR160W MTR10 involved in nuclear protein import YOR185C GSP2 GTP-binding protein of the RAS superfamily YOR206W NOC2 crucial for intranuclear movement of ribosomal precursor particles YPL124W NIP29 nuclear import protein YPL125W KAP120 nuclear transport factor, member of karyopherin-beta family mitochondrial transport (80 ORFs) 08.04 80 YAR035W YAT1 carnitine acetyltransferase, mitochondrial YBL030C PET9 ADP/ATP carrier protein (MCF) YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR085W AAC3 ADP/ATP carrier protein (MCF) YBR091C MRS5 subunit of the TIM22-complex YBR104W YMC2 mitochondrial carrier protein (MCF) YBR192W RIM2 mitochondrial carrier protein (MCF) YBR291C CTP1 citrate transport protein, mitochondrial (MCF) YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL119C YDL119C similarity to bovine Graves disease carrier protein YDL198C YHM1 member of the mitochondrial carrier family (MCF) YDL217C TIM22 subunit of the TIM22-complex YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR322C-A TIM11 subunit E of the dimeric form of mitochondrial F1F0-ATPase YEL006W YEL006W similarity to peroxisomal membrane and mitochondrial carrier proteins YEL020W-A TIM9 essential subunit of the TIM22-complex for mitochondrial protein import YEL059C-A SOM1 required for mitochondrial IMP1 peptidase function YER024W YAT2 carnitine O-acetyltransferase YER053C YER053C strong similarity to mitochondrial phosphate carrier protein YGR028W MSP1 intra-mitochondrial sorting protein YGR082W TOM20 mitochondrial outer membrane import receptor subunit, 20 kD YGR096W YGR096W hypothetical mitochondrial transport protein YGR257C YGR257C similarity to C.elegans C16C10.1 YHR002W YHR002W similarity to bovine mitochondrial carrier protein/Grave's disease carrier protein YHR005C-A MRS11 subunit of the TIM22-complex YHR050W SMF2 probable manganese transporter YHR117W TOM71 protein with similarity to TOM70P/Mas70p YIL006W YIL006W similarity to FLX1P YIL022W TIM44 mitochondrial inner membrane import receptor subunit YIL114C POR2 voltage dependent anion channel (YVDAC2) YIL134W FLX1 FAD carrier protein (MCF), mitochondrial YJL054W TIM54 translocase for the insertion of proteins into the mitochondrial inner membrane YJL133W MRS3 RNA splicing protein and member of the mitochondrial carrier family (MCF) YJL143W TIM17 mitochondrial inner membrane import translocase subunit YJR045C SSC1 mitochondrial heat shock protein 70-related protein YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YJR095W SFC1 succinate-fumarate transporter YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YJR135W-A TIM8 delivers Proteins across the intermembrane space of mitochondria to the TIM22 complex YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL120W OAC1 similarity to mitochondrial uncoupling proteins (MCF) YKR052C MRS4 RNA splicing protein and member of the mitochondrial carrier family (MCF) YLL024C SSA2 heat shock protein of HSP70 family, cytosolic YLR295C ATP14 F1F0-ATPase complex, subunit h YLR348C DIC1 dicarboxylate carrier protein YML042W CAT2 carnitine O-acetyltransferase YML062C MFT1 mitochondrial fusion target protein YMR056C AAC1 ADP/ATP carrier protein (MCF) YMR060C TOM37 mitochondrial outer membrane import receptor subunit, 37 kD YMR166C YMR166C similarity to members of the mitochondrial carrier protein family YMR203W TOM40 forms the hydrophilic channel of the mitochondrial import pore for preproteins YMR301C ATM1 ATP-binding cassette transporter protein, mitochondrial YNL003C PET8 member of the mitochondrial carrier (MCF) family YNL055C POR1 mitochondrial outer membrane porin YNL064C YDJ1 mitochondrial and ER import protein YNL070W TOM7 mitochondrial outer membrane import receptor subunit, 7 kD YNL083W YNL083W weak similarity to rabbit peroxisomal Ca-dependent solute carrier YNL121C TOM70 mitochondrial outer membrane specialized import receptor YNL131W TOM22 mitochondrial outer membrane import receptor complex subunit YNR017W MAS6 mitochondrial inner membrane import translocase subunit YOL077W-A ATP19 subunit K of the dimeric form of mitochondrial F1F0-ATP synthase YOR037W CYC2 cytochrome-c mitochondrial import factor YOR045W TOM6 mitochondrial outer membrane import receptor subunit, 6 kD YOR100C CRC1 mitochondrial carnitine carrier, member of the mitochondrial carrier (MCF) family YOR130C ORT1 ornithine transport protein of mitochondria involved in arginine metabolism, member of the mitochondrial carrier family (MCF) YOR222W ODC2 similarity to ADP/ATP carrier proteins YOR232W MGE1 heat shock protein - chaperone YOR316C COT1 cobalt accumulation protein YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL134C ODC1 similarity to ADP,ATP carrier proteins YPL224C MMT2 mitochondrial iron transporter YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPR011C YPR011C similarity to ADP/ATP carrier proteins and Graves disease carrier protein YPR021C YPR021C similarity to human citrate transporter protein YPR058W YMC1 mitochondrial carrier protein (MCF) YPR133W-A TOM5 mitochondrial outer membrane protein Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 vesicular transport (Golgi network, etc.) (129 ORFs) 08.07 129 YAL007C ERP2 p24 protein involved in membrane trafficking YAL026C DRS2 P-type amino-phospholipids-ATPase YAL030W SNC1 synaptic vesicle-associated membrane protein YAL042W ERV46 component of copii vesicles involved in transport between the ER and golgi complex YAR002C-A ERP1 p24 protein involved in membrane trafficking YBL017C PEP1 vacuolar protein sorting/targeting protein YBL040C ERD2 ER lumen protein-retaining receptor YBL050W SEC17 transport vesicle fusion protein YBR080C SEC18 vesicular-fusion protein, functional homolog of NSF YBR097W VPS15 ser/thr protein kinase YBR164C ARL1 ADP-ribosylation factor YBR254C TRS20 TRAPP subunit of 20 kDa involved in targeting and fusion of ER to golgi transport vesicles YBR264C YPT10 similarity to GTP-binding proteins YCR067C SED4 protein of the endoplasmic reticulum YDL058W USO1 intracellular protein transport protein YDL137W ARF2 GTP-binding protein of the ARF family YDL145C COP1 coatomer complex alpha chain of secretory pathway vesicles YDL192W ARF1 small GTP-binding protein of the ARF family YDL195W SEC31 component of the COPII coat of ER-golgi vesicles YDR027C LUV1 interacts with the beta-tubulin binding protein RBL2P YDR107C YDR107C strong similarity to EMP70 protein YDR108W GSG1 sporulation specific protein YDR170C SEC7 component of non-clathrin vesicle coat YDR189W SLY1 hydrophilic suppressor of YPT1 and member of the SEC1P family YDR238C SEC26 coatomer complex beta chain of secretory pathway vesicles YDR246W TRS23 TRAPP subunit of 20 kDa involved in targeting and fusion of ER to golgi transport vesicles YDR299W BFR2 involved in protein transport steps at the Brefeldin A blocks YDR320C SWA2 clathrin-binding protein required for normal clathrin function and for uncoating of clathrin-coated vesicles YDR407C TRS120 TRAPP subunit of 120 kDa involved in targeting and fusion of ER to golgi transport vesicles YDR456W NHX1 NA+-H+ antiporter YDR468C TLG1 member of the syntaxin family of t-SNAREs YDR472W TRS31 TRAPP subunit of 31 kDa involved in targeting and fusion of ER to golgi transport vesicles YDR484W SAC2 suppressor of actin mutation YDR498C SEC20 secretory pathway protein YEL022W GEA2 GDP/GTP exchange factor for ARF YER031C YPT31 GTP-binding protein of the rab family YER039C HVG1 strong similarity to vanadate resistance protein GOG5P YER157W SEC34 required for vesicle tethering to the yeast Golgi apparatus YFL005W SEC4 GTP-binding protein of the ras superfamily YFL025C BST1 negative regulator of COPII vesicle formation YFL038C YPT1 GTP-binding protein of the rab family YFR051C RET2 coatomer complex delta chain YGL054C ERV14 ER-derived Vesicles YGL095C VPS45 vacuolar protein sorting-associated protein YGL137W SEC27 coatomer complex beta' chain (beta'-cop) of secretory pathway vesicles YGL145W TIP20 required for ER to Golgi transport YGL167C PMR1 Ca2+-transporting P-type ATPase YGL200C EMP24 component of the COPII-coated vesicles, 24 kDa YGL210W YPT32 small GTP-binding protein essential for Golgi function YGL225W GOG5 GDP-mannose transporter into the lumen of the Golgi YGL233W SEC15 vesicular traffic control protein YGR009C SEC9 protein transport protein YGR057C LST7 required for amino acid permease transport from the Golgi to the cell surface YGR120C SEC35 required for ER to golgi vesicle docking YGR166W KRE11 beta-glucan synthesis-associated protein YGR167W CLC1 clathrin light chain YGR172C YIP1 golgi membrane protein YHL031C GOS1 SNARE protein of Golgi compartment YHR012W VPS29 involved in vacuolar protein sorting YHR108W GGA2 Arf-binding protein YHR127W HSN1 hypothetical protein YHR135C YCK1 casein kinase I isoform YHR142W CHS7 control of protein export from the ER (like chitin synthase III) YIL004C BET1 protein transport protein YIL076W SEC28 epsilon-COP coatomer subunit YIL109C SEC24 component of COPII coat of ER-Golgi vesicles YJL004C SYS1 multi copy suppressor of YPT6 YJL029C VPS53 subunit of VP52-54 complex, required for protein sorting at the yeast late Golgi YJL154C VPS35 protein-sorting protein, vacuolar YJL193W YJL193W similarity to SLY41P YJR031C GEA1 GDP/GTP exchange factor for ARF YKL006C-A SFT1 SNARE-like protein YKL196C YKT6 SNARE protein for Endoplasmic Reticulum-Golgi transport YKL212W SAC1 recessive suppressor of secretory defect YKR054C DYN1 dynein heavy chain, cytosolic YKR068C BET3 involved in targeting and fusion of ER to golgi transport vesicles YLL024C SSA2 heat shock protein of HSP70 family, cytosolic YLR026C SED5 syntaxin (T-SNARE) YLR078C BOS1 secretory pathway protein YLR083C EMP70 endosomal protein YLR148W PEP3 vacuolar membrane protein YLR208W SEC13 protein transport protein YLR262C YPT6 GTP-binding protein of the rab family YLR268W SEC22 synaptobrevin (V-SNARE) YLR309C IMH1 involved in vesicular transport YLR396C VPS33 vacuolar sorting protein YML001W YPT7 GTP-binding protein of the RAB family YML012W ERV25 component of the COPII-coated vesicles, 25 Kda YML049C RSE1 involved in RNA splicing and ER to Golgi transport YML067C ERV41 component of copii vesicles involved in transport between the ER and golgi complex YML077W BET5 involved in targeting and fusion of ER to golgi transport vesicles YML097C VPS9 vacuolar sorting protein YMR017W SPO20 DBF2P interacting protein YMR079W SEC14 phosphatidylinositol(PI)/phosphatidylcholine(PC) transfer protein YMR183C SSO2 syntaxin (T-SNARE) YMR197C VTI1 v-SNARE: involved in Golgi retrograde protein traffic YMR218C TRS130 TRAPP subunit of 130 kDa involved in targeting and fusion of ER to golgi transport vesicles YMR231W PEP5 vacuolar biogenesis protein YNL006W LST8 required for transport of permeases from the golgi to the plasma membrane YNL044W YIP3 protein of unknown function YNL064C YDJ1 mitochondrial and ER import protein YNL263C YIF1 SLH1P Interacting Factor YNL272C SEC2 protein transport protein YNL287W SEC21 coatomer complex gamma chain (gamma-COP) of secretory pathway vesicles YNL304W YPT11 similarity to YPT1P and rab GTP-binding proteins YNR006W VPS27 vacuolar protein sorting-associated protein YNR026C SEC12 GDP/GTP exchange factor for SAR1P YOL018C TLG2 member of the syntaxin family of t-SNAREs YOL062C APM4 AP-2 complex subunit, mu2 subunit, 55 KD YOR070C GYP1 GTPase activating protein for YPT1P and SEC4P YOR075W UFE1 syntaxin (T-SNARE) of the ER YOR094W ARF3 ADP-ribosylation factor 3 YOR115C TRS33 TRAPP subunit of 33 kDa involved in targeting and fusion of ER to golgi transport vesicles YOR216C RUD3 suppressor of USO1-1 transport defect YOR326W MYO2 myosin heavy chain YOR327C SNC2 synaptobrevin (v-SNARE) homolog present on post-Golgi vesicles YPL010W RET3 coatomer complex zeta chain YPL045W VPS16 vacuolar sorting protein YPL051W ARL3 ADP-ribosylation factor-like protein, member of the arf-sar family in the ras superfamily YPL085W SEC16 multidomain vesicle coat protein YPL120W VPS30 involved in vacuolare protein sorting and autophagy YPL145C KES1 involved in ergosterol biosynthesis YPL218W SAR1 GTP-binding protein of the ARF family YPL232W SSO1 syntaxin-related protein YPL259C APM1 AP-1 complex subunit, mu1 subunit, 54 KD YPR017C DSS4 GDP/GTP exchange factor for SEC4P YPR028W YIP2 Ypt-interacting protein YPR095C SYT1 guanine nucleotide exchange factor, contains a conserved SEC7P-domain YPR181C SEC23 component of COPII coat of ER-golgi vesicles peroxisomal transport (16 ORFs) 08.10 16 YAL055W PEX22 peroxisomal matrix protein import YDR142C PEX7 peroxisomal import protein - peroxin YDR244W PEX5 peroxisomal targeting signal receptor YDR329C PEX3 peroxisomal assembly protein - peroxin YER015W FAA2 long-chain-fatty-acid--CoA ligase YGL153W PEX14 peroxisomal protein involved in protein import - peroxin YGR239C PEX21 peroxin, essential for peroxisomal targeting by the PTS2 pathway YHR160C PEX18 peroxin, essential for peroxisomal targeting by the PTS2 pathway YIR004W DJP1 DnaJ-like protein involved specifically in peroxisomal protein import YJL210W PEX2 peroxisomal assembly protein - peroxin YKL188C PXA2 ABC transporter, peroxisomal YLR191W PEX13 peroxisomal protein involved in protein import - peroxin YML042W CAT2 carnitine O-acetyltransferase YNL214W PEX17 component of the peroxisomal protein translocation - peroxin YOL044W PEX15 required for peroxisome assembly - peroxin YPL147W PXA1 long-chain fatty acid transporter vacuolar transport (56 ORFs) 08.13 56 YAL002W VPS8 vacuolar sorting protein, 134 kD YBL017C PEP1 vacuolar protein sorting/targeting protein YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR097W VPS15 ser/thr protein kinase YBR105C VID24 required for vacuolar import and degradation of FBP1P YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YCL008C STP22 required for vacuolar targeting of temperature-sensitive plasma membrane proteins, STE2P and CAN1P YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR135C YCF1 glutathione S-conjugate transporter, vacuolar YDR177W UBC1 E2 ubiquitin-conjugating enzyme YDR323C PEP7 vacuolar segregation protein YDR468C TLG1 member of the syntaxin family of t-SNAREs YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YER031C YPT31 GTP-binding protein of the rab family YFR019W FAB1 phosphatidylinositol 3-phosphate 5-kinase YGL006W PMC1 Ca2+-transporting P-type ATPase YGL095C VPS45 vacuolar protein sorting-associated protein YGL180W APG1 essential for autophagocytosis YGL212W VAM7 vacuolar morphogenesis protein YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YHR012W VPS29 involved in vacuolar protein sorting YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YJL154C VPS35 protein-sorting protein, vacuolar YJL222W VTH2 strong similarity to PEP1P YKL002W DID4 class E vacuolar-protein sorting and endocytosis factor YKL041W VPS24 endosomal Vps protein complex subunit YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL175W ZRT3 vacuolar membrane protein involved in the regulation of zinc storage YKR014C YPT52 GTP-binding protein of the rab family YKR035W-A DID2 class E vacuolar-protein sorting and endocytosis factor YLR025W SNF7 class E Vps protein YLR309C IMH1 involved in vesicular transport YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YML097C VPS9 vacuolar sorting protein YMR004W MVP1 required for vacuolar protein sorting YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YNL093W YPT53 GTP-binding protein of the RAB family (RAS superfamily) YNR006W VPS27 vacuolar protein sorting-associated protein YNR007C AUT1 essential for autophagocytosis YOL018C TLG2 member of the syntaxin family of t-SNAREs YOR036W PEP12 syntaxin (T-SNARE), vacuolar YOR089C VPS21 GTP-binding protein YOR106W VAM3 syntaxin (t-SNARE) YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YPL019C VTC3 strong similarity to YFL004w, similarity to YJL012c YPL065W VPS28 involved in vacuolar traffic YPL120W VPS30 involved in vacuolare protein sorting and autophagy YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar YPR173C VPS4 vacuolar sorting protein YPR185W APG13 protein required for the autophagic process extracellular transport, exocytosis and secretion (38 ORFs) 08.16 38 YAL048C YAL048C vacuolar aspartic proteasse YBL050W SEC17 transport vesicle fusion protein YBL106C SRO77 polarized exocytosis by regulating SNARE function YBR080C SEC18 vesicular-fusion protein, functional homolog of NSF YBR102C EXO84 exocyst protein essential for secretion YBR162W-A YSY6 secretory pathway protein YCR032W BPH1 similarity to human beige-like protein and mouse lysosomal trafficking regulator YDL226C GCS1 ADP-ribosylation factor GTPase-activating protein (ARF-GAP) YDR129C SAC6 actin filament bundling protein, fimbrin YDR164C SEC1 protein transport protein YDR166C SEC5 required for exocytosis YER006W YER006W similarity to P.polycephalum myosin-related protein mlpA YER008C SEC3 component of exocyst complex YER136W GDI1 GDP dissociation inhibitor YGL233W SEC15 vesicular traffic control protein YGR009C SEC9 protein transport protein YGR131W YGR131W strong similarity to Nce2p YGR191W HIP1 histidine permease YIL068C SEC6 protein transport protein YJL044C GYP6 GTPase-activating protein YJL085W EXO70 70 kDa exocyst component protein YJL093C TOK1 outward-rectifier potassium channel YJL205C-A NCE101 involved in non-classical protein export pathway YKL209C STE6 ATP-binding cassette transporter protein YKL212W SAC1 recessive suppressor of secretory defect YLL043W FPS1 glycerol channel protein YLR166C SEC10 required for exocytosis YLR250W SSP120 secretory protein YNL036W NCE103 involved in non-classical protein export pathway YNL272C SEC2 protein transport protein YNL325C FIG4 weak similarity to inositol phosphatase YNR049C MSO1 secretion protein, multicopy suppressor of SEC1 YOR307C SLY41 secretory pathway protein YOR326W MYO2 myosin heavy chain YPL232W SSO1 syntaxin-related protein YPR032W SRO7 polarized exocytosis by regulating SNARE function YPR055W SEC8 protein transport protein YPR149W NCE102 involved in non-classical protein export pathway cellular import (100 ORFs) 08.19 100 YBL037W APL3 AP-2 complex subunit, alpha-adaptin, 113 KD YBL050W SEC17 transport vesicle fusion protein YBR021W FUR4 uracil permease YBR068C BAP2 leucine permease, high-affinity (S1) YBR069C TAT1 amino acid permease YBR080C SEC18 vesicular-fusion protein, functional homolog of NSF YBR109C CMD1 calmodulin YBR288C APM3 AP-3 complex subunit, mu3 subunit, 55 KD YBR294W SUL1 high-affinity sulfate transport protein YBR298C MAL31 maltose permease YCL040W GLK1 aldohexose specific glucokinase YCR009C RVS161 similarity to human amphiphysin and RVS167P YDL029W ARP2 actin-like protein YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL210W UGA4 GABA-specific high-affinity permease YDL226C GCS1 ADP-ribosylation factor GTPase-activating protein (ARF-GAP) YDR046C BAP3 valine transporter YDR129C SAC6 actin filament bundling protein, fimbrin YDR342C HXT7 high-affinity hexose transporter YDR343C HXT6 high-affinity hexose transporter YDR345C HXT3 low-affinity hexose transporter YDR468C TLG1 member of the syntaxin family of t-SNAREs YDR497C ITR1 myo-inositol permease, major YEL063C CAN1 amino acid permease YEL069C HXT13 high-affinity hexose transporter YER031C YPT31 GTP-binding protein of the rab family YER056C FCY2 purine-cytosine permease YFL011W HXT10 hexose transporter YFL039C ACT1 actin YFL041W FET5 multicopy oxidase YFL050C ALR2 divalent cation transprter YGL077C HNM1 choline permease YGL206C CHC1 clathrin heavy chain YGR055W MUP1 high affinity methionine permease YGR121C MEP1 ammonia permease of high capacity and moderate affinity YGR167W CLC1 clathrin light chain YGR191W HIP1 histidine permease YGR241C YAP1802 Yeast Adaptor Protein, member of AP180 protein family YGR261C APL6 AP-3 complex subunit, beta3-adaptin, 91 KD YHL036W MUP3 very low affinity methionine permease YHR092C HXT4 moderate- to low-affinity glucose transporter YHR094C HXT1 low-affinity hexose transporter YHR096C HXT5 member of the hexose transporter family YHR161C YAP1801 Yeast Adaptor Protein, member of AP180 protein family YHR175W CTR2 copper transport protein YIL170W HXT12 strong similarity to sugar transport proteins YIR006C PAN1 actin-cytoskeleton assembly protein YIR028W DAL4 allantoin permease YJL024C APS3 AP-3 complex subunit, sigma3 subunit, 22 KD YJL129C TRK1 potassium transport protein TRK1P, high-affinity YJL214W HXT8 hexose transport protein YJL219W HXT9 hexose transport protein YJR005W APL1 AP-2 complex subunit, beta2-adaptin, 78 KD YJR040W GEF1 voltage-gated chloride channel protein YJR058C APS2 AP-2 complex subunit, sigma2 subunit, 17 KD YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR152W DAL5 allantoate permease YJR158W HXT16 member of the hexose transporter family of the major facilitator superfamily [MFS] YKL135C APL2 AP-1 complex subunit, beta1-adaptin, 82 KD YKR014C YPT52 GTP-binding protein of the rab family YKR039W GAP1 general amino acid permease YKR050W TRK2 moderate-affinity potassium transport protein YLL043W FPS1 glycerol channel protein YLL050C COF1 cofilin, actin binding and severing protein YLR081W GAL2 galactose (and glucose) permease YLR088W GAA1 required for attachment of GPI anchor onto proteins YLR170C APS1 AP-1 complex subunit, sigma1 subunit, 18 KD YLR240W VPS34 phosphatidylinositol 3-kinase YLR337C VRP1 verprolin YML001W YPT7 GTP-binding protein of the RAB family YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YMR011W HXT2 high-affinity hexose transporter YMR058W FET3 cell surface ferroxidase, high affinity YMR243C ZRC1 zinc- and cadmium resistance protein YMR319C FET4 low affinity Fe(II) iron transport protein YNL084C END3 required for endocytosis and cytoskeletal organization YNL093W YPT53 GTP-binding protein of the RAB family (RAS superfamily) YNL142W MEP2 high affinity low capacity ammonia permease YNL154C YCK2 casein kinase I isoform YNL243W SLA2 cytoskeleton assembly control protein YNL268W LYP1 lysine-specific high-affinity permease YNL270C ALP1 high-affinity permease for basic amino acids YNL318C HXT14 hexose transport protein YNR026C SEC12 GDP/GTP exchange factor for SAR1P YNR072W HXT17 sugar transport protein YOL018C TLG2 member of the syntaxin family of t-SNAREs YOL020W TAT2 high affinity tryptophan transport protein YOL103W ITR2 myo-inositol permease, minor YOL122C SMF1 manganese transporter YOL130W ALR1 divalent cation transporter YOL156W HXT11 low affinity glucose transport protein YOR034C AKR2 involved in constitutive endocytosis of STE3P YOR035C SHE4 required for mother cell-specific gene expression YOR089C VPS21 GTP-binding protein YOR329C SCD5 suppressor of clathrin deficiency YOR348C PUT4 proline and gamma-aminobutyrate permease YPL195W APL5 AP-3 complex subunit, gamma-adaptin, 107 KD YPR029C APL4 AP-1 complex subunit, gamma-adaptin, 94 KD YPR124W CTR1 copper transport protein YPR129W SCD6 suppressor of clathrin deficiency cytoskeleton-dependent transport (27 ORFs) 08.22 27 YAL029C MYO4 myosin heavy chain, unconventional (class V) isoform YBL063W KIP1 kinesin-related protein YBL078C AUT7 essential for autophagy YBR172C SMY2 kinesin-related protein YDR424C DYN2 dynein light chain 1, cytosolic YDR488C PAC11 required in the absence of CIN8P YEL061C CIN8 kinesin-related protein YGL216W KIP3 kinesin-related protein required for nuclear migration YHR023W MYO1 myosin-1 isoform (type II myosin) heavy chain YHR129C ARP1 centractin YHR156C YHR156C weak similarity to mouse kinesin KIF3B YIL062C ARC15 subunit of the ARP2/3 complex YJR065C ARP3 actin related protein YKL013C ARC19 subunit of the ARP2/3 complex YKL079W SMY1 kinesin-related protein YKL129C MYO3 myosin type I YKR054C DYN1 dynein heavy chain, cytosolic YLR370C ARC18 subunit of the ARP2/3 complex YMR109W MYO5 myosin I YMR198W CIK1 spindle pole body associated protein YMR294W JNM1 mitosis protein, involved in nuclear migration YNL223W AUT2 essential for autophagy YNR035C ARC35 subunit of the ARP2/3 complex YOR326W MYO2 myosin heavy chain YPL155C KIP2 kinesin-related protein YPL174C NIP100 component of the dynactin complex YPR141C KAR3 kinesin-related protein other intracellular transport activities (32 ORFs) 08.99 32 YBR170C NPL4 nuclear protein localization factor and ER translocation component YBR171W SEC66 ER protein-translocation complex subunit YCR075C ERS1 intracellular protein transport protein YDL018C ERP3 weak similarity to DEP1P YDL161W ENT1 clathrin binding protein, required for endocytosis YDR040C ENA1 P-type ATPase involved in Na+ and Li+ efflux YDR086C SSS1 ER protein-translocase complex subunit YDR117C YDR117C similarity to mouse ligatin, a trafficking receptor for phosphoglycoproteins YER019C-A SBH2 ER protein-translocation complex subunit YER060W FCY21 purine-cytosine permease YER060W-A FCY22 purine/cytosine permease with similarity to FCY2P YER087C-B SBH1 involved in translocation into the ER YGL002W ERP6 strong similarity to human gp25L2 protein YHL019C APM2 involved in clathrin-independent transport processes YHR110W ERP5 similarity to human gp25L2 protein YHR123W EPT1 sn-1,2-diacylglycerol ethanolamine- and cholinephosphotransferase YHR195W NVJ1 part of nucleus-vacuole junctions YIR006C PAN1 actin-cytoskeleton assembly protein YJL034W KAR2 nuclear fusion protein YJL099W CHS6 chitin biosynthesis protein YJR059W PTK2 involved in polyamine uptake YKL198C PTK1 polyamine transport enhancing protein YKL199C YKT9 PTK1-YKT9 overlapping sequences may arise from a gene duplication event involving chromosomes X and XI YKR093W PTR2 peptide transporter YLR206W ENT2 clathrin binding protein, required for endocytosis YLR292C SEC72 ER protein-translocation complex subunit YLR378C SEC61 ER protein-translocation complex subunit YNL079C TPM1 tropomyosin 1 YNL183C NPR1 ser/thr protein kinase YOR254C SEC63 ER protein-translocation complex subunit YPL094C SEC62 ER protein-translocation complex subunit YPR009W YPR009W similarity to sterol uptake protein SUT1P CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION MECHANISM (59 ORFs) 10 59 YBR260C RGD1 similarity to C.elegans GTPase-activating protein YCR027C RSG1 rheb-like Gene involved in growth regulation YDL035C GPR1 G-protein coupled receptor YDL090C RAM1 protein farnesyltransferase, beta subunit YDL101C DUN1 protein kinase YDL212W SHR3 endoplasmatic reticulum membrane protein YDL230W PTP1 protein tyrosine phosphatase YDR099W BMH2 suppressor of clathrin deficiency YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR287W YDR287W similarity to inositolmonophosphatases YDR315C IPK1 inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IP5 2-kinase) YDR373W FRQ1 regulator of phosphatidylinositol-4-OH kinase protein YDR379W RGA2 similarity to Dbm1p and to the rat GAP-associated protein p190 YER019W ISC1 weak similarity to human and mouse neutral sphingomyelinase YER020W GPA2 guanine nucleotide-binding regulatory protein YER177W BMH1 14-3-3 protein involved in rapamycin-sensitive signalling YFL026W STE2 pheromone alpha-factor receptor YFL031W HAC1 transcription factor YFR014C CMK1 Ca2+/calmodulin-dependent ser/thr protein kinase type I YGR136W LSB1 weak similarity to chicken growth factor receptor-binding protein GRB2 homolog YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YHL002W YHL002W weak similarity to mammalian signal transducing adaptor YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR046C YHR046C similarity to inositolmonophosphatases YHR079C IRE1 protein kinase YHR146W CRP1 similarity to pheromone-response G-protein MDG1P YHR206W SKN7 transcription factor with similarity to HSF1P YIL002C INP51 phosphatidylinositol phosphate 5-phosphatase YIL147C SLN1 two-component signal transducer YJL005W CYR1 adenylate cyclase YJL146W IDS2 IME2-dependent signaling protein YJL164C TPK1 cAMP-dependent protein kinase 1, catalytic chain YJR066W TOR1 phosphatidylinositol 3-kinase YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YKL166C TPK3 cAMP-dependent protein kinase 3, catalytic chain YKL178C STE3 pheromone a-factor receptor YKL203C TOR2 phosphatidylinositol 3-kinase YLR150W STM1 specific affinity for guanine-rich quadruplex nucleic acids YLR229C CDC42 GTP-binding protein of RAS superfamily YLR240W VPS34 phosphatidylinositol 3-kinase YLR305C STT4 phosphatidylinositol-4-kinase YML064C TEM1 GTP-binding protein of the RAS superfamily YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR028W TAP42 component of the Tor signaling pathway YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL098C RAS2 GTP-binding protein YNL128W TEP1 weak similarity to tensin and to the mammalian tumor suppressor gene product MMAC1/PTEN/TEP1 YNL132W KRE33 similarity to A.ambisexualis antheridiol steroid receptor YNL138W SRV2 adenylate cyclase-associated protein, 70kDa YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YNL267W PIK1 phosphatidylinositol 4-kinase YOL016C CMK2 Ca2+/calmodulin-dependent ser/thr protein kinase, type II YOR101W RAS1 GTP-binding protein YOR107W RGS2 negative regulator of glucose-induced cAMP signaling pathway YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YPL153C RAD53 ser/thr/tyr protein kinase YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YPR054W SMK1 sporulation-specific MAP kinase YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins intracellular signalling (55 ORFs) 10.01 55 YBR260C RGD1 similarity to C.elegans GTPase-activating protein YCR027C RSG1 rheb-like Gene involved in growth regulation YDL090C RAM1 protein farnesyltransferase, beta subunit YDL101C DUN1 protein kinase YDL212W SHR3 endoplasmatic reticulum membrane protein YDL230W PTP1 protein tyrosine phosphatase YDR099W BMH2 suppressor of clathrin deficiency YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR287W YDR287W similarity to inositolmonophosphatases YDR315C IPK1 inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IP5 2-kinase) YDR373W FRQ1 regulator of phosphatidylinositol-4-OH kinase protein YDR379W RGA2 similarity to Dbm1p and to the rat GAP-associated protein p190 YER019W ISC1 weak similarity to human and mouse neutral sphingomyelinase YER020W GPA2 guanine nucleotide-binding regulatory protein YER177W BMH1 14-3-3 protein involved in rapamycin-sensitive signalling YFL031W HAC1 transcription factor YFR014C CMK1 Ca2+/calmodulin-dependent ser/thr protein kinase type I YGR136W LSB1 weak similarity to chicken growth factor receptor-binding protein GRB2 homolog YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YHL002W YHL002W weak similarity to mammalian signal transducing adaptor YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR046C YHR046C similarity to inositolmonophosphatases YHR079C IRE1 protein kinase YHR146W CRP1 similarity to pheromone-response G-protein MDG1P YHR206W SKN7 transcription factor with similarity to HSF1P YIL002C INP51 phosphatidylinositol phosphate 5-phosphatase YJL005W CYR1 adenylate cyclase YJL146W IDS2 IME2-dependent signaling protein YJL164C TPK1 cAMP-dependent protein kinase 1, catalytic chain YJR066W TOR1 phosphatidylinositol 3-kinase YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YKL166C TPK3 cAMP-dependent protein kinase 3, catalytic chain YKL203C TOR2 phosphatidylinositol 3-kinase YLR150W STM1 specific affinity for guanine-rich quadruplex nucleic acids YLR229C CDC42 GTP-binding protein of RAS superfamily YLR240W VPS34 phosphatidylinositol 3-kinase YLR305C STT4 phosphatidylinositol-4-kinase YML064C TEM1 GTP-binding protein of the RAS superfamily YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR028W TAP42 component of the Tor signaling pathway YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL098C RAS2 GTP-binding protein YNL128W TEP1 weak similarity to tensin and to the mammalian tumor suppressor gene product MMAC1/PTEN/TEP1 YNL132W KRE33 similarity to A.ambisexualis antheridiol steroid receptor YNL138W SRV2 adenylate cyclase-associated protein, 70kDa YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YNL267W PIK1 phosphatidylinositol 4-kinase YOL016C CMK2 Ca2+/calmodulin-dependent ser/thr protein kinase, type II YOR101W RAS1 GTP-binding protein YOR107W RGS2 negative regulator of glucose-induced cAMP signaling pathway YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YPL153C RAD53 ser/thr/tyr protein kinase YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YPR054W SMK1 sporulation-specific MAP kinase YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins unspecified signal transduction (4 ORFs) 10.01.01 4 YDL230W PTP1 protein tyrosine phosphatase YDR099W BMH2 suppressor of clathrin deficiency YDR315C IPK1 inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IP5 2-kinase) YER177W BMH1 14-3-3 protein involved in rapamycin-sensitive signalling enzyme mediated signal transduction (12 ORFs) 10.01.05 12 YER020W GPA2 guanine nucleotide-binding regulatory protein YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR146W CRP1 similarity to pheromone-response G-protein MDG1P YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YLR229C CDC42 GTP-binding protein of RAS superfamily YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL098C RAS2 GTP-binding protein YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YOR101W RAS1 GTP-binding protein YOR107W RGS2 negative regulator of glucose-induced cAMP signaling pathway YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins G-protein mediated signal transduction (12 ORFs) 10.01.05.05 12 YER020W GPA2 guanine nucleotide-binding regulatory protein YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR146W CRP1 similarity to pheromone-response G-protein MDG1P YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YLR229C CDC42 GTP-binding protein of RAS superfamily YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL098C RAS2 GTP-binding protein YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YOR101W RAS1 GTP-binding protein YOR107W RGS2 negative regulator of glucose-induced cAMP signaling pathway YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins second messenger mediated signal transduction (2 ORFs) 10.01.09 2 YER019W ISC1 weak similarity to human and mouse neutral sphingomyelinase YJL005W CYR1 adenylate cyclase polyphosphoinositol mediated signal transduction (1 ORF) 10.01.09.11 1 YER019W ISC1 weak similarity to human and mouse neutral sphingomyelinase other intracellular signal transduction activities (37 ORFs) 10.01.99 37 YBR260C RGD1 similarity to C.elegans GTPase-activating protein YCR027C RSG1 rheb-like Gene involved in growth regulation YDL090C RAM1 protein farnesyltransferase, beta subunit YDL101C DUN1 protein kinase YDL212W SHR3 endoplasmatic reticulum membrane protein YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR287W YDR287W similarity to inositolmonophosphatases YDR373W FRQ1 regulator of phosphatidylinositol-4-OH kinase protein YDR379W RGA2 similarity to Dbm1p and to the rat GAP-associated protein p190 YFL031W HAC1 transcription factor YFR014C CMK1 Ca2+/calmodulin-dependent ser/thr protein kinase type I YGR136W LSB1 weak similarity to chicken growth factor receptor-binding protein GRB2 homolog YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YHL002W YHL002W weak similarity to mammalian signal transducing adaptor YHR046C YHR046C similarity to inositolmonophosphatases YHR079C IRE1 protein kinase YHR206W SKN7 transcription factor with similarity to HSF1P YIL002C INP51 phosphatidylinositol phosphate 5-phosphatase YJL146W IDS2 IME2-dependent signaling protein YJL164C TPK1 cAMP-dependent protein kinase 1, catalytic chain YJR066W TOR1 phosphatidylinositol 3-kinase YKL166C TPK3 cAMP-dependent protein kinase 3, catalytic chain YKL203C TOR2 phosphatidylinositol 3-kinase YLR150W STM1 specific affinity for guanine-rich quadruplex nucleic acids YLR240W VPS34 phosphatidylinositol 3-kinase YLR305C STT4 phosphatidylinositol-4-kinase YML064C TEM1 GTP-binding protein of the RAS superfamily YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR028W TAP42 component of the Tor signaling pathway YNL128W TEP1 weak similarity to tensin and to the mammalian tumor suppressor gene product MMAC1/PTEN/TEP1 YNL132W KRE33 similarity to A.ambisexualis antheridiol steroid receptor YNL138W SRV2 adenylate cyclase-associated protein, 70kDa YNL267W PIK1 phosphatidylinositol 4-kinase YOL016C CMK2 Ca2+/calmodulin-dependent ser/thr protein kinase, type II YPL153C RAD53 ser/thr/tyr protein kinase YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YPR054W SMK1 sporulation-specific MAP kinase transmembrane signal transduction (4 ORFs) 10.05 4 YDL035C GPR1 G-protein coupled receptor YFL026W STE2 pheromone alpha-factor receptor YIL147C SLN1 two-component signal transducer YKL178C STE3 pheromone a-factor receptor CELL RESCUE, DEFENSE AND VIRULENCE (278 ORFs) 11 278 YAL005C SSA1 heat shock protein of HSP70 family, cytosolic YAL015C NTG1 DNA repair protein YAL040C CLN3 cyclin, G1/S-specific YAR020C PAU7 strong similarity to members of the SRP1P/TIP1P family YBL005W PDR3 pleiotropic drug resistance regulatory protein YBL009W YBL009W strong similarity to DNA damage responsive ALK1P YBL064C YBL064C strong similarity to thiol-specific antioxidant enzyme YBL075C SSA3 heat shock protein of HSP70 family, cytosolic YBL093C ROX3 transcription factor YBL105C PKC1 ser/thr protein kinase YBR008C FLR1 fluconazole resistance protein YBR043C YBR043C similarity to benomyl/methotrexate resistance protein YBR044C TCM62 chaperone required for assembly of mitochondrial succinate dehydrogenase YBR054W YRO2 strong similarity to HSP30 heat shock protein Yro1p YBR067C TIP1 esterase YBR070C SAT2 osmotolerance protein YBR072W HSP26 heat shock protein YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR103W SIF2 SIR4P interacting protein YBR126C TPS1 alpha,alpha-trehalose-phosphate synthase, 56 KD subunit YBR131W CCZ1 Calcium Caffeine Zinc sensitivity YBR145W ADH5 alcohol dehydrogenase V YBR169C SSE2 heat shock protein of the HSP70 family YBR180W DTR1 dityrosine transporter YBR244W GPX2 glutathione peroxidases YBR293W YBR293W similarity to multidrug resistance proteins YCL035C GRX1 glutaredoxin YCL069W YCL069W strong similarity to drug resistance protein SGE1 YCL073C YCL073C strong similarity to subtelomeric encoded proteins YCR008W SAT4 serine/threonine-specific protein kinase YCR021C HSP30 heat shock protein YCR023C YCR023C weak similarity to E.coli tetracycline resistance protein TCR1 YCR060W YCR060W similarity to stress inducible protein STI1P YCR073C SSK22 MAP kinase kinase kinase YCR083W TRX3 mitochondrial thioredoxin YCR104W PAU3 strong similarity to members of the SRP1/TIP1P family YDL006W PTC1 protein serine/threonine phosphatase 2c YDL022W GPD1 glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic YDL025C YDL025C similarity to probable protein kinase NPR1 YDL100C YDL100C similarity to E.coli arsenical pump-driving ATPase YDL168W SFA1 long-chain alcohol dehydrogenase YDR011W SNQ2 multidrug resistance protein YDR033W MRH1 membrane protein related to HSP30P YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR074W TPS2 alpha,alpha-trehalose-phosphate synthase, 102 KD subunit YDR077W SED1 abundant cell surface glycoprotein YDR098C GRX3 member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5) YDR119W YDR119W similarity to B.subtilis tetracyclin resistance YDR135C YCF1 glutathione S-conjugate transporter, vacuolar YDR155C CPH1 cyclophilin (peptidylprolyl isomerase) YDR227W SIR4 silencing regulatory and DNA-repair protein YDR251W PAM1 coiled-coil protein multicopy suppressor of loss of PP2A YDR256C CTA1 catalase A, peroxisomal YDR258C HSP78 heat shock protein of clpb family of ATP-dependent proteases, mitochondrial YDR263C DIN7 DNA-damage inducible protein YDR293C SSD1 involved in the tolerance to high concentration of Ca2+ YDR402C DIT2 cytochrome P450 56 YDR404C RPB7 DNA-directed RNA polymerase II, 19 KD subunit YDR423C CAD1 transcriptional activator YDR436W PPZ2 protein ser/thr phosphatase of the PP-1 family YDR453C YDR453C strong similarity to thiol-specific antioxidant proteins YDR456W NHX1 NA+-H+ antiporter YDR477W SNF1 carbon catabolite derepressing ser/thr protein kinase YDR513W TTR1 glutaredoxin YDR519W FKB2 FK506/rapamycin-binding protein of the ER YDR538W PAD1 phenylacrylic acid decarboxylase YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL030W ECM10 heat shock protein of HSP70 family YEL039C CYC7 cytochrome-c isoform 2 YEL049W PAU2 strong similarity to members of the SRP1P/TIP1P family YEL065W SIT1 probable multidrug resistance protein YER011W TIR1 cold-shock induced protein of the TIR1P,TIP1P family YER012W PRE1 20S proteasome subunit C11(beta4) YER042W MXR1 responsible for the reduction of methionine sulfoxide YER057C HMF1 Heat-shock induceable Inhibiter of cell Growth YER062C HOR2 DL-glycerol phosphatase YER076C YER076C similarity to killer toxin Khr1p YER103W SSA4 heat shock protein of HSP70 family, cytosolic YER118C SHO1 involved in the HOG1 high-osmolarity signal transduction pathway YER125W RSP5 hect domain E3 ubiquitin-protein ligase YER143W DDI1 induced in response to DNA alkylation damage YER174C GRX4 member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5) YER185W YER185W strong similarity to Rtm1p YER187W YER187W similarity to killer toxin KHS precursor YFL014W HSP12 heat shock protein YFL016C MDJ1 heat shock protein - chaperone YFL020C PAU5 strong similarity to members of the SRP1P/TIP1P family YFL050C ALR2 divalent cation transprter YFL053W DAK2 dihydroxyacetone kinase YFL059W SNZ3 strong similarity to Para rubber tree ethylene-responsive protein1 YFL060C SNO3 strong similarity to SNO1 and SNO2 YFR022W YFR022W similarity to ROD1P YFR052W RPN12 26S proteasome regulatory subunit YGL013C PDR1 transcription factor YGL021W ALK1 DNA damage-responsive protein YGL073W HSF1 heat shock transcription factor YGL115W SNF4 nuclear regulatory protein YGL128C YGL128C weak similarity to dnaJ proteins YGL178W MPT5 multicopy suppressor of POP2 YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL190C CDC55 ser/thr phosphatase 2A regulatory subunit B YGL213C SKI8 antiviral protein of the beta-transducin (WD-40) repeat family YGL254W FZF1 sulfite resistance protein YGR088W CTT1 catalase T, cytosolic YGR100W MDR1 MAC1P interacting protein YGR138C TPO2 polyamine transport protein YGR159C NSR1 nuclear localization sequence binding protein YGR197C SNG1 involved in nitroguanidine resistance YGR209C TRX2 thioredoxin II YGR213C RTA1 involved in 7-aminocholesterol resistance YGR224W AZR1 strong similarity to drug resistance protein SGE1, YKR105c and YCL069W YGR234W YHB1 flavohemoglobin YGR249W MGA1 similarity to heat shock transcription factors YGR253C PUP2 20S proteasome subunit(alpha5) YGR271W SLH1 strong similarity to S.pombe RNA helicase YHL028W WSC4 Cell wall integrity and stress response component 4 YHL040C ARN1 ferrichrome-type siderophore transporter YHL046C YHL046C strong similarity to members of the SRP1P/TIP1P family YHL047C TAF1 siderophore transporter for triacetylfusarinine C YHR007C ERG11 cytochrome P450 lanosterol 14a-demethylase YHR008C SOD2 superoxide dismutase (Mn) precursor, mitochondrial YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR032W ERC1 ethionine resistance protein YHR042W NCP1 NADPH-cytochrome P450 reductase YHR048W YHR048W similarity to multidrug resistance proteins YHR053C CUP1-1 metallothionein YHR055C CUP1-2 metallothionein YHR057C CYP2 peptidyl-prolyl cis-trans isomerase YHR064C PDR13 regulator protein involved in pleiotropic drug resistance YHR079C IRE1 protein kinase YHR104W GRE3 aldose reductase YHR135C YCK1 casein kinase I isoform YHR206W SKN7 transcription factor with similarity to HSF1P YIL011W TIR3 strong similarity to members of the SRP1P/TIP1P family YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL120W QDR1 similarity to antibiotic resistance proteins YIL121W YIL121W similarity to antibiotic resistance proteins YIL147C SLN1 two-component signal transducer YIR002C MPH1 protection of the genome from spontaneous and chemically induced damage YIR037W HYR1 glutathione peroxidase YIR038C GTT1 glutathione S-transferase YJL001W PRE3 20S proteasome subunit (beta1) YJL095W BCK1 ser/thr protein kinase of the MEKK family YJL101C GSH1 glutamate--cysteine ligase YJL128C PBS2 tyrosine protein kinase of the MAP kinase kinase family YJL134W LCB3 sphingoid base-phosphate phosphatase YJL140W RPB4 DNA-directed RNA polymerase II, 32 kDa subunit YJL158C CIS3 strong similarity to PIR1P/HSP150P/PIR3P family YJL159W HSP150 member of the PIR1P/HSP150P/PIR3P family YJL160C YJL160C strong similarity to PIR1P/HSP150P/PIR3P family YJL165C HAL5 ser/thr protein kinase YJL223C PAU1 strong similarity to members of the SRP1P/TIP1P family YJR015W YJR015W strong similarity to SNG1P YJR045C SSC1 mitochondrial heat shock protein 70-related protein YJR051W OSM1 osmotic growth protein YJR055W HIT1 required for growth at high temperature YJR069C HAM1 controls 6-N-hydroxylaminopurine sensitivity and mutagenesis YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR104C SOD1 copper-zinc superoxide dismutase YJR147W HMS2 High-copy MEP2 Suppressor YKL026C GPX1 glutathione peroxidase YKL033W-A YKL033W-A strong similarity to holacid-halidohydrolase YKL062W MSN4 transcriptional activator YKL064W MNR2 overexpression overcomes manganese toxicity YKL088W YKL088W similarity to C.tropicalis hal3 protein, to C-term. of SIS2P and to hypothetical protein YOR054c YKL110C KTI12 involved in resistance to K.lactis killer toxin YKL143W LTV1 low-temperature viability protein YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL163W PIR3 member of the PIR1P/Pir2p/PIR3P family YKL164C PIR1 required for tolerance to heat shock YKL210W UBA1 E1-like (ubiquitin-activating) enzyme YKR042W UTH1 involved in the aging process YKR053C YSR3 dihydrosphingosine-1-phosphate phosphatase YKR066C CCP1 cytochrome-c peroxidase precursor YKR103W YKR103W similarity to multidrug resistance proteins YKR104W YKR104W similarity to multidrug resistance proteins YKR105C YKR105C strong similarity to SGE1P and hypothetical protein YCL069w YKR106W YKR106W strong similarity to subtelomeric encoded proteins YLL003W SFI1 similarity to Xenopus laevis XCAP-C YLL015W BPT1 similarity to YCF1P, YOR1P, rat organic anion transporter YLL026W HSP104 heat shock protein YLL028W TPO1 polyamine transport protein YLL039C UBI4 ubiquitin YLL043W FPS1 glycerol channel protein YLL057C YLL057C similarity to E.coli dioxygenase YLL060C GTT2 glutathione S-transferase YLR006C SSK1 two-component signal transducer YLR043C TRX1 thioredoxin I YLR046C YLR046C strong similarity to RTA1P and Rtm1p protein YLR109W AHP1 Alkyl hydroperoxide reductase YLR113W HOG1 ser/thr protein kinase of MAP kinase (MAPK) family YLR259C HSP60 heat shock protein - chaperone, mitochondrial YLR369W SSQ1 mitochondrial heat shock protein 70 YLR398C SKI2 antiviral protein and putative helicase YLR461W PAU4 strong similarity to members of the TIR1P/TIP1P family YML007W YAP1 transcriptional activator involved in oxidative stress response YML016C PPZ1 ser/thr phosphatase required for normal osmoregulation YML028W TSA1 thiol-specific antioxidant YML058W-A HUG1 hydroxyurea and UV and gamma radiation induced YML070W DAK1 dihydroxyacetone kinase, induced in high salt YML086C ALO1 D-arabinono-1,4-lactone oxidase YML116W ATR1 aminotriazole and 4-nitroquinoline resistance protein YMR015C ERG5 C-22 sterol desaturase YMR021C MAC1 metal binding activator YMR022W QRI8 E2 ubiquitin-conjugation enzyme YMR037C MSN2 stress responsive regulatory protein YMR038C LYS7 copper chaperone for superoxide dismutase SOD1P YMR043W MCM1 transcription factor of the MADS box family YMR088C YMR088C similarity to multidrug resistance proteins YMR095C SNO1 similarity to M.leprae hisH protein YMR096W SNZ1 stationary phase protein YMR173W DDR48 heat shock protein YMR174C PAI3 protease A (ysca) inhibitor IA3 YMR175W SIP18 osmotic stress protein YMR186W HSC82 heat shock protein YMR243C ZRC1 zinc- and cadmium resistance protein YMR251W-A HOR7 hyperosmolarity-responsive protein YMR273C ZDS1 involved in negative regulation of cell polarity YMR279C YMR279C strong similarity to aminotriazole resistance protein YNL027W CRZ1 calcineurin responsive zinc-finger YNL064C YDJ1 mitochondrial and ER import protein YNL065W AQR1 similarity to resistance proteins YNL098C RAS2 GTP-binding protein YNL154C YCK2 casein kinase I isoform YNL160W YGP1 secreted glycoprotein YNL239W LAP3 member of the GAL regulon YNL241C ZWF1 glucose-6-phosphate dehydrogenase YNL259C ATX1 antioxidant protein and metal homeostasis factor YNL328C MDJ2 heat shock protein - chaperone YNL333W SNZ2 putative pyridoxine (vitamin B6) biosynthetic enzyme YNL334C SNO2 strong similarity to hypothetical proteins YFL060c and YMR095c YNR031C SSK2 MAP kinase kinase kinase of the high osmolarity signal transduction pathway YNR055C HOL1 member of major facilitator superfamily multidrug-resistance protein subfamily 1 YNR070W YNR070W strong similarity to SNQ2P YNR076W PAU6 strong similarity to members of the TIR1P/TIP1P family YOL052C SPE2 adenosylmethionine decarboxylase precursor YOL052C-A DDR2 heat shock protein DDRA2 YOL064C MET22 protein ser/thr phosphatase YOL089C HAL9 transcriptional activator of ENA1 YOL105C WSC3 cell wall integrity and stress response component 3 YOL130W ALR1 divalent cation transporter YOL158C ENB1 a gene of the major facilitator superfamily encodes a transporter for enterobactin YOL161C YOL161C strong similarity to members of the SRP1P/TIP1P family YOR008C SLG1 required for cell wall integrity and for stress response YOR009W TIR4 similarity to TIR1P and TIR2P YOR010C TIR2 cold shock induced protein YOR014W RTS1 potential regulatory subunit of protein phosphatase 2A YOR018W ROD1 O-dinitrobenzene,calcium and zinc resistance protein YOR027W STI1 stress-induced protein YOR031W CRS5 suppressor of cup1 deletion, metallothionein-like protein YOR054C YOR054C similarity to SIS2P protein and C.tropicalis hal3 protein YOR079C ATX2 multicopy suppressor of SOD-linked defects YOR153W PDR5 pleiotropic drug resistance protein YOR163W DDP1 diadenosine hexaphosphate (Ap6A) hydrolase YOR208W PTP2 protein-tyrosine-phosphatase YOR231W MKK1 ser/thr protein kinase YOR247W SRL1 similarity to vanadate sensitive suppressor SVS1P YOR251C YOR251C similarity to thiosulfate sulfurtransferases YOR266W PNT1 pentamidine resistance factor YOR273C TPO4 polyamine transporter YOR378W YOR378W strong similarity to aminotriazole resistance protein YPL059W GRX5 member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5) YPL084W BRO1 required for normal response to nutrient limitation YPL091W GLR1 glutathione reductase (NADPH) YPL092W SSU1 sulfite sensitivity protein YPL106C SSE1 heat shock protein of HSP70 family YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL163C SVS1 vanadate sensitive suppressor YPL194W DDC1 DNA damage checkpoint protein YPL223C GRE1 induced by osmotic stress YPL240C HSP82 heat shock protein YPR005C HAL1 salt-induced protein YPR026W ATH1 acid trehalase, vacuolar YPR141C KAR3 kinesin-related protein YPR156C TPO3 polyamine transporter YPR189W SKI3 antiviral protein YPR198W SGE1 drug resistance protein YPR200C ARR2 arsenate reductase stress response (175 ORFs) 11.01 175 YAL005C SSA1 heat shock protein of HSP70 family, cytosolic YAL015C NTG1 DNA repair protein YAL040C CLN3 cyclin, G1/S-specific YAR020C PAU7 strong similarity to members of the SRP1P/TIP1P family YBL009W YBL009W strong similarity to DNA damage responsive ALK1P YBL075C SSA3 heat shock protein of HSP70 family, cytosolic YBL093C ROX3 transcription factor YBL105C PKC1 ser/thr protein kinase YBR044C TCM62 chaperone required for assembly of mitochondrial succinate dehydrogenase YBR054W YRO2 strong similarity to HSP30 heat shock protein Yro1p YBR067C TIP1 esterase YBR070C SAT2 osmotolerance protein YBR072W HSP26 heat shock protein YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR103W SIF2 SIR4P interacting protein YBR126C TPS1 alpha,alpha-trehalose-phosphate synthase, 56 KD subunit YBR169C SSE2 heat shock protein of the HSP70 family YCL035C GRX1 glutaredoxin YCR008W SAT4 serine/threonine-specific protein kinase YCR021C HSP30 heat shock protein YCR060W YCR060W similarity to stress inducible protein STI1P YCR073C SSK22 MAP kinase kinase kinase YCR083W TRX3 mitochondrial thioredoxin YCR104W PAU3 strong similarity to members of the SRP1/TIP1P family YDL006W PTC1 protein serine/threonine phosphatase 2c YDL022W GPD1 glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic YDL025C YDL025C similarity to probable protein kinase NPR1 YDR033W MRH1 membrane protein related to HSP30P YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR074W TPS2 alpha,alpha-trehalose-phosphate synthase, 102 KD subunit YDR077W SED1 abundant cell surface glycoprotein YDR098C GRX3 member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5) YDR155C CPH1 cyclophilin (peptidylprolyl isomerase) YDR227W SIR4 silencing regulatory and DNA-repair protein YDR251W PAM1 coiled-coil protein multicopy suppressor of loss of PP2A YDR258C HSP78 heat shock protein of clpb family of ATP-dependent proteases, mitochondrial YDR263C DIN7 DNA-damage inducible protein YDR293C SSD1 involved in the tolerance to high concentration of Ca2+ YDR404C RPB7 DNA-directed RNA polymerase II, 19 KD subunit YDR436W PPZ2 protein ser/thr phosphatase of the PP-1 family YDR456W NHX1 NA+-H+ antiporter YDR477W SNF1 carbon catabolite derepressing ser/thr protein kinase YDR513W TTR1 glutaredoxin YDR519W FKB2 FK506/rapamycin-binding protein of the ER YEL030W ECM10 heat shock protein of HSP70 family YEL039C CYC7 cytochrome-c isoform 2 YEL049W PAU2 strong similarity to members of the SRP1P/TIP1P family YER011W TIR1 cold-shock induced protein of the TIR1P,TIP1P family YER042W MXR1 responsible for the reduction of methionine sulfoxide YER057C HMF1 Heat-shock induceable Inhibiter of cell Growth YER062C HOR2 DL-glycerol phosphatase YER103W SSA4 heat shock protein of HSP70 family, cytosolic YER118C SHO1 involved in the HOG1 high-osmolarity signal transduction pathway YER125W RSP5 hect domain E3 ubiquitin-protein ligase YER143W DDI1 induced in response to DNA alkylation damage YER174C GRX4 member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5) YFL014W HSP12 heat shock protein YFL016C MDJ1 heat shock protein - chaperone YFL020C PAU5 strong similarity to members of the SRP1P/TIP1P family YFL053W DAK2 dihydroxyacetone kinase YFL059W SNZ3 strong similarity to Para rubber tree ethylene-responsive protein1 YFL060C SNO3 strong similarity to SNO1 and SNO2 YFR052W RPN12 26S proteasome regulatory subunit YGL021W ALK1 DNA damage-responsive protein YGL073W HSF1 heat shock transcription factor YGL115W SNF4 nuclear regulatory protein YGL128C YGL128C weak similarity to dnaJ proteins YGL178W MPT5 multicopy suppressor of POP2 YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL190C CDC55 ser/thr phosphatase 2A regulatory subunit B YGR088W CTT1 catalase T, cytosolic YGR100W MDR1 MAC1P interacting protein YGR159C NSR1 nuclear localization sequence binding protein YGR234W YHB1 flavohemoglobin YGR249W MGA1 similarity to heat shock transcription factors YHL028W WSC4 Cell wall integrity and stress response component 4 YHL046C YHL046C strong similarity to members of the SRP1P/TIP1P family YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR057C CYP2 peptidyl-prolyl cis-trans isomerase YHR064C PDR13 regulator protein involved in pleiotropic drug resistance YHR079C IRE1 protein kinase YHR104W GRE3 aldose reductase YHR135C YCK1 casein kinase I isoform YHR206W SKN7 transcription factor with similarity to HSF1P YIL011W TIR3 strong similarity to members of the SRP1P/TIP1P family YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL147C SLN1 two-component signal transducer YIR037W HYR1 glutathione peroxidase YIR038C GTT1 glutathione S-transferase YJL095W BCK1 ser/thr protein kinase of the MEKK family YJL128C PBS2 tyrosine protein kinase of the MAP kinase kinase family YJL134W LCB3 sphingoid base-phosphate phosphatase YJL140W RPB4 DNA-directed RNA polymerase II, 32 kDa subunit YJL158C CIS3 strong similarity to PIR1P/HSP150P/PIR3P family YJL159W HSP150 member of the PIR1P/HSP150P/PIR3P family YJL160C YJL160C strong similarity to PIR1P/HSP150P/PIR3P family YJL165C HAL5 ser/thr protein kinase YJL223C PAU1 strong similarity to members of the SRP1P/TIP1P family YJR045C SSC1 mitochondrial heat shock protein 70-related protein YJR051W OSM1 osmotic growth protein YJR055W HIT1 required for growth at high temperature YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR147W HMS2 High-copy MEP2 Suppressor YKL062W MSN4 transcriptional activator YKL088W YKL088W similarity to C.tropicalis hal3 protein, to C-term. of SIS2P and to hypothetical protein YOR054c YKL143W LTV1 low-temperature viability protein YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL163W PIR3 member of the PIR1P/Pir2p/PIR3P family YKL164C PIR1 required for tolerance to heat shock YKL210W UBA1 E1-like (ubiquitin-activating) enzyme YKR042W UTH1 involved in the aging process YKR053C YSR3 dihydrosphingosine-1-phosphate phosphatase YLL003W SFI1 similarity to Xenopus laevis XCAP-C YLL026W HSP104 heat shock protein YLL039C UBI4 ubiquitin YLL043W FPS1 glycerol channel protein YLL060C GTT2 glutathione S-transferase YLR006C SSK1 two-component signal transducer YLR109W AHP1 Alkyl hydroperoxide reductase YLR113W HOG1 ser/thr protein kinase of MAP kinase (MAPK) family YLR259C HSP60 heat shock protein - chaperone, mitochondrial YLR369W SSQ1 mitochondrial heat shock protein 70 YLR461W PAU4 strong similarity to members of the TIR1P/TIP1P family YML007W YAP1 transcriptional activator involved in oxidative stress response YML016C PPZ1 ser/thr phosphatase required for normal osmoregulation YML058W-A HUG1 hydroxyurea and UV and gamma radiation induced YML070W DAK1 dihydroxyacetone kinase, induced in high salt YML086C ALO1 D-arabinono-1,4-lactone oxidase YMR021C MAC1 metal binding activator YMR022W QRI8 E2 ubiquitin-conjugation enzyme YMR037C MSN2 stress responsive regulatory protein YMR043W MCM1 transcription factor of the MADS box family YMR095C SNO1 similarity to M.leprae hisH protein YMR096W SNZ1 stationary phase protein YMR173W DDR48 heat shock protein YMR174C PAI3 protease A (ysca) inhibitor IA3 YMR175W SIP18 osmotic stress protein YMR186W HSC82 heat shock protein YMR251W-A HOR7 hyperosmolarity-responsive protein YMR273C ZDS1 involved in negative regulation of cell polarity YNL027W CRZ1 calcineurin responsive zinc-finger YNL064C YDJ1 mitochondrial and ER import protein YNL098C RAS2 GTP-binding protein YNL154C YCK2 casein kinase I isoform YNL160W YGP1 secreted glycoprotein YNL241C ZWF1 glucose-6-phosphate dehydrogenase YNL328C MDJ2 heat shock protein - chaperone YNL333W SNZ2 putative pyridoxine (vitamin B6) biosynthetic enzyme YNL334C SNO2 strong similarity to hypothetical proteins YFL060c and YMR095c YNR031C SSK2 MAP kinase kinase kinase of the high osmolarity signal transduction pathway YNR076W PAU6 strong similarity to members of the TIR1P/TIP1P family YOL052C-A DDR2 heat shock protein DDRA2 YOL064C MET22 protein ser/thr phosphatase YOL089C HAL9 transcriptional activator of ENA1 YOL105C WSC3 cell wall integrity and stress response component 3 YOL161C YOL161C strong similarity to members of the SRP1P/TIP1P family YOR008C SLG1 required for cell wall integrity and for stress response YOR009W TIR4 similarity to TIR1P and TIR2P YOR010C TIR2 cold shock induced protein YOR014W RTS1 potential regulatory subunit of protein phosphatase 2A YOR027W STI1 stress-induced protein YOR054C YOR054C similarity to SIS2P protein and C.tropicalis hal3 protein YOR208W PTP2 protein-tyrosine-phosphatase YOR231W MKK1 ser/thr protein kinase YPL059W GRX5 member of the subfamily of yeast glutaredoxins (Grx3, GRX4, and Grx5) YPL084W BRO1 required for normal response to nutrient limitation YPL091W GLR1 glutathione reductase (NADPH) YPL106C SSE1 heat shock protein of HSP70 family YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL194W DDC1 DNA damage checkpoint protein YPL223C GRE1 induced by osmotic stress YPL240C HSP82 heat shock protein YPR005C HAL1 salt-induced protein YPR026W ATH1 acid trehalase, vacuolar YPR141C KAR3 kinesin-related protein detoxification (102 ORFs) 11.07 102 YBL005W PDR3 pleiotropic drug resistance regulatory protein YBL064C YBL064C strong similarity to thiol-specific antioxidant enzyme YBR008C FLR1 fluconazole resistance protein YBR043C YBR043C similarity to benomyl/methotrexate resistance protein YBR131W CCZ1 Calcium Caffeine Zinc sensitivity YBR145W ADH5 alcohol dehydrogenase V YBR180W DTR1 dityrosine transporter YBR244W GPX2 glutathione peroxidases YBR293W YBR293W similarity to multidrug resistance proteins YCL035C GRX1 glutaredoxin YCL069W YCL069W strong similarity to drug resistance protein SGE1 YCL073C YCL073C strong similarity to subtelomeric encoded proteins YCR023C YCR023C weak similarity to E.coli tetracycline resistance protein TCR1 YCR083W TRX3 mitochondrial thioredoxin YDL100C YDL100C similarity to E.coli arsenical pump-driving ATPase YDL168W SFA1 long-chain alcohol dehydrogenase YDR011W SNQ2 multidrug resistance protein YDR119W YDR119W similarity to B.subtilis tetracyclin resistance YDR135C YCF1 glutathione S-conjugate transporter, vacuolar YDR256C CTA1 catalase A, peroxisomal YDR402C DIT2 cytochrome P450 56 YDR423C CAD1 transcriptional activator YDR453C YDR453C strong similarity to thiol-specific antioxidant proteins YDR513W TTR1 glutaredoxin YDR538W PAD1 phenylacrylic acid decarboxylase YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL065W SIT1 probable multidrug resistance protein YER185W YER185W strong similarity to Rtm1p YFL050C ALR2 divalent cation transprter YFR022W YFR022W similarity to ROD1P YGL013C PDR1 transcription factor YGL254W FZF1 sulfite resistance protein YGR088W CTT1 catalase T, cytosolic YGR138C TPO2 polyamine transport protein YGR197C SNG1 involved in nitroguanidine resistance YGR209C TRX2 thioredoxin II YGR224W AZR1 strong similarity to drug resistance protein SGE1, YKR105c and YCL069W YGR271W SLH1 strong similarity to S.pombe RNA helicase YHL040C ARN1 ferrichrome-type siderophore transporter YHL047C TAF1 siderophore transporter for triacetylfusarinine C YHR007C ERG11 cytochrome P450 lanosterol 14a-demethylase YHR008C SOD2 superoxide dismutase (Mn) precursor, mitochondrial YHR032W ERC1 ethionine resistance protein YHR042W NCP1 NADPH-cytochrome P450 reductase YHR048W YHR048W similarity to multidrug resistance proteins YHR053C CUP1-1 metallothionein YHR055C CUP1-2 metallothionein YIL120W QDR1 similarity to antibiotic resistance proteins YIL121W YIL121W similarity to antibiotic resistance proteins YIR002C MPH1 protection of the genome from spontaneous and chemically induced damage YIR038C GTT1 glutathione S-transferase YJL101C GSH1 glutamate--cysteine ligase YJR015W YJR015W strong similarity to SNG1P YJR104C SOD1 copper-zinc superoxide dismutase YKL026C GPX1 glutathione peroxidase YKL033W-A YKL033W-A strong similarity to holacid-halidohydrolase YKL064W MNR2 overexpression overcomes manganese toxicity YKR066C CCP1 cytochrome-c peroxidase precursor YKR103W YKR103W similarity to multidrug resistance proteins YKR104W YKR104W similarity to multidrug resistance proteins YKR105C YKR105C strong similarity to SGE1P and hypothetical protein YCL069w YKR106W YKR106W strong similarity to subtelomeric encoded proteins YLL015W BPT1 similarity to YCF1P, YOR1P, rat organic anion transporter YLL028W TPO1 polyamine transport protein YLL057C YLL057C similarity to E.coli dioxygenase YLL060C GTT2 glutathione S-transferase YLR043C TRX1 thioredoxin I YLR046C YLR046C strong similarity to RTA1P and Rtm1p protein YLR398C SKI2 antiviral protein and putative helicase YML028W TSA1 thiol-specific antioxidant YML116W ATR1 aminotriazole and 4-nitroquinoline resistance protein YMR015C ERG5 C-22 sterol desaturase YMR038C LYS7 copper chaperone for superoxide dismutase SOD1P YMR043W MCM1 transcription factor of the MADS box family YMR088C YMR088C similarity to multidrug resistance proteins YMR243C ZRC1 zinc- and cadmium resistance protein YMR279C YMR279C strong similarity to aminotriazole resistance protein YNL065W AQR1 similarity to resistance proteins YNL239W LAP3 member of the GAL regulon YNL241C ZWF1 glucose-6-phosphate dehydrogenase YNL259C ATX1 antioxidant protein and metal homeostasis factor YNR055C HOL1 member of major facilitator superfamily multidrug-resistance protein subfamily 1 YNR070W YNR070W strong similarity to SNQ2P YOL052C SPE2 adenosylmethionine decarboxylase precursor YOL130W ALR1 divalent cation transporter YOL158C ENB1 a gene of the major facilitator superfamily encodes a transporter for enterobactin YOR018W ROD1 O-dinitrobenzene,calcium and zinc resistance protein YOR031W CRS5 suppressor of cup1 deletion, metallothionein-like protein YOR079C ATX2 multicopy suppressor of SOD-linked defects YOR153W PDR5 pleiotropic drug resistance protein YOR163W DDP1 diadenosine hexaphosphate (Ap6A) hydrolase YOR247W SRL1 similarity to vanadate sensitive suppressor SVS1P YOR251C YOR251C similarity to thiosulfate sulfurtransferases YOR266W PNT1 pentamidine resistance factor YOR273C TPO4 polyamine transporter YOR378W YOR378W strong similarity to aminotriazole resistance protein YPL091W GLR1 glutathione reductase (NADPH) YPL092W SSU1 sulfite sensitivity protein YPL163C SVS1 vanadate sensitive suppressor YPR156C TPO3 polyamine transporter YPR198W SGE1 drug resistance protein YPR200C ARR2 arsenate reductase detoxification involving cytochrome P450 (4 ORFs) 11.07.01 4 YDR402C DIT2 cytochrome P450 56 YHR007C ERG11 cytochrome P450 lanosterol 14a-demethylase YLL057C YLL057C similarity to E.coli dioxygenase YMR015C ERG5 C-22 sterol desaturase other detoxification (2 ORFs) 11.07.99 2 YCR083W TRX3 mitochondrial thioredoxin YOR163W DDP1 diadenosine hexaphosphate (Ap6A) hydrolase degradation of foreign (exogenous) compounds (1 ORF) 11.10 1 YGL213C SKI8 antiviral protein of the beta-transducin (WD-40) repeat family degradation of foreign (exogenous) polynucleotides (1 ORF) 11.10.03 1 YGL213C SKI8 antiviral protein of the beta-transducin (WD-40) repeat family other cell rescue activities (9 ORFs) 11.99 9 YER012W PRE1 20S proteasome subunit C11(beta4) YER076C YER076C similarity to killer toxin Khr1p YER187W YER187W similarity to killer toxin KHS precursor YGR213C RTA1 involved in 7-aminocholesterol resistance YGR253C PUP2 20S proteasome subunit(alpha5) YJL001W PRE3 20S proteasome subunit (beta1) YJR069C HAM1 controls 6-N-hydroxylaminopurine sensitivity and mutagenesis YKL110C KTI12 involved in resistance to K.lactis killer toxin YPR189W SKI3 antiviral protein REGULATION OF / INTERACTION WITH CELLULAR ENVIRONMENT (199 ORFs) 13 199 YAL041W CDC24 GTP/GDP exchange factor for CDC42P YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBR024W SCO2 involved in stability of COX1P and COX2P YBR037C SCO1 involved in stabilization of COX1P and COX2P YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YBR129C OPY1 pheromone resistant yeast 1 YBR140C IRA1 inhibitory regulator protein of the ras-cyclic AMP pathway YBR195C MSI1 chromatin assembly complex, subunit p50 YBR207W FTH1 similarity to Iron permease FTR1P (YER145c) YBR235W YBR235W similarity to bumetanide-sensitive Na-K-Cl cotransport protein YBR290W BSD2 metal homeostasis protein YBR294W SUL1 high-affinity sulfate transport protein YBR295W PCA1 P-type Cu2+-transporting ATPase YBR296C PHO89 Na+-coupled phosphate transport protein, high affinity YCL017C NFS1 regulates Iron-Sulfur cluster proteins, cellular Iron uptake, andIron distribution YCL027W FUS1 cell fusion protein YCL032W STE50 pheromone response pathway protein YCL037C SRO9 La motif-containing proteins that modulate mRNA translation YCR021C HSP30 heat shock protein YCR024C-A PMP1 H+-ATPase subunit, plasma membrane YCR037C PHO87 member of the phosphate permease family YCR044C PER1 involved in manganese homeostasis YCR073C SSK22 MAP kinase kinase kinase YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL006W PTC1 protein serine/threonine phosphatase 2c YDL022W GPD1 glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic YDL035C GPR1 G-protein coupled receptor YDL120W YFH1 regulates mitochondrial iron accumulation YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDL159W STE7 ser/thr/tyr protein kinase of MAP kinase kinase family YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL235C YPD1 phosphorelay intermediate between SLN1P and SSK1P YDR011W SNQ2 multidrug resistance protein YDR038C ENA5 P-type ATPase involved in Na+ efflux YDR039C ENA2 P-type ATPase involved in Na+ efflux YDR040C ENA1 P-type ATPase involved in Na+ and Li+ efflux YDR069C DOA4 ubiquitin-specific protease YDR103W STE5 pheromone signal transduction pathway protein YDR182W CDC1 cell division control protein YDR183W PLP1 Phosducin homologue likely to be involved in regulation of pheromone response YDR184C ATC1 binds Aip3p YDR264C AKR1 ankyrin repeat-containing protein YDR270W CCC2 probable copper-transporting ATPase YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR309C GIC2 CDC42 GTPase-binding protein YDR456W NHX1 NA+-H+ antiporter YDR461W MFA1 mating pheromone a-factor 1 YDR506C YDR506C similarity to FET3, YFL041w and F.floriforme diphenol oxidase YDR515W SLF1 La motif-containing proteins that modulate mRNA translation YEL017C-A PMP2 H+-ATPase subunit, plasma membrane YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL031W SPF1 P-type ATPase YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YER020W GPA2 guanine nucleotide-binding regulatory protein YER118C SHO1 involved in the HOG1 high-osmolarity signal transduction pathway YER145C FTR1 iron permease that mediates high-affinity iron uptake YFL014W HSP12 heat shock protein YFL026W STE2 pheromone alpha-factor receptor YFL041W FET5 multicopy oxidase YFL050C ALR2 divalent cation transprter YGL006W PMC1 Ca2+-transporting P-type ATPase YGL008C PMA1 H+-transporting P-type ATPase, major isoform, plasma membrane YGL071W RCS1 iron-regulated transcriptional repressor YGL096W TOS8 similarity to copper homeostasis protein CUP9P YGL160W YGL160W similarity to hypothetical protein YLR047c and FRE2P YGL166W CUP2 copper-dependent transcription factor YGL167C PMR1 Ca2+-transporting P-type ATPase YGL178W MPT5 multicopy suppressor of POP2 YGL255W ZRT1 high-affinity zinc transport protein YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YGR040W KSS1 ser/thr protein kinase of the MAP kinase family YGR142W BTN2 Gene/protein whose expression is elevated in a btn1 minus/Btn1p lacking yeast strain YGR191W HIP1 histidine permease YGR217W CCH1 calcium channel protein YGR238C KEL2 involved in cell fusion and morphogenesis YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHL016C DUR3 urea transport protein YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YHR061C GIC1 CDC42 GTPase-binding protein YHR084W STE12 transcriptional activator YHR146W CRP1 similarity to pheromone-response G-protein MDG1P YHR158C KEL1 involved in cell fusion and morphology YHR175W CTR2 copper transport protein YHR205W SCH9 serine/threonine protein kinase involved in stress response and nutrient-sensing signaling pathway YIL047C SYG1 member of the major facilitator superfamily YIL119C RPI1 negative regulator of ras-cAMP pathway YIL147C SLN1 two-component signal transducer YIR026C YVH1 protein tyrosine phosphatase YJL005W CYR1 adenylate cyclase YJL093C TOK1 outward-rectifier potassium channel YJL094C KHA1 K+/H+ exchanger YJL117W PHO86 inorganic phospate transporter YJL128C PBS2 tyrosine protein kinase of the MAP kinase kinase family YJL129C TRK1 potassium transport protein TRK1P, high-affinity YJL156C SSY5 part of an extracellular amino acid sensor YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJL198W PHO90 low affinity phosphate transporter YJR040W GEF1 voltage-gated chloride channel protein YJR049C UTR1 associated with ferric reductase activity YJR059W PTK2 involved in polyamine uptake YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YJR126C YJR126C similarity to human prostate-specific membrane antigen and transferrin receptor protein YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL040C NFU1 iron homeostasis YKL064W MNR2 overexpression overcomes manganese toxicity YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL134C OCT1 mitochondrial intermediate peptidase YKL159C RCN1 inhibitor of calcineurin YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL178C STE3 pheromone a-factor receptor YKL185W ASH1 negative regulator of HO transcription YKL190W CNB1 calcineurin B, regulatory subunit YKL198C PTK1 polyamine transport enhancing protein YKL220C FRE2 ferric (and cupric) reductase YLL009C COX17 interacts genetically with SCO1 and SCO2 in cytochrome oxidase assembly YLL016W SDC25 GDP/GTP exchange factor (GEF) YLL021W SPA2 involved in cell polarity YLL027W ISA1 mitochondrial protein required for normal iron metabolism YLL051C FRE6 strong similarity to ferric reductase FRE2P YLR006C SSK1 two-component signal transducer YLR034C SMF3 strong similarity to SMF2 protein and S.pombe hypothetical protein YLR092W SUL2 sulfate transporter YLR109W AHP1 Alkyl hydroperoxide reductase YLR113W HOG1 ser/thr protein kinase of MAP kinase (MAPK) family YLR130C ZRT2 low affininty zinc transporter YLR138W NHA1 putative Na+/H+ antiporter YLR178C TFS1 CDC25-dependent nutrient- and ammonia-response cell-cycle regulator YLR214W FRE1 ferric (and cupric) reductase YLR220W CCC1 involved in calcium regulation YLR229C CDC42 GTP-binding protein of RAS superfamily YLR295C ATP14 F1F0-ATPase complex, subunit h YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR336C SGD1 involved in HOG pathway YLR362W STE11 ser/thr protein kinase of the MEKK family YLR369W SSQ1 mitochondrial heat shock protein 70 YLR411W CTR3 copper transport protein YLR433C CNA1 calcineurin B, catalytic subunit YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YLR452C SST2 involved in desensitization to alpha-factor pheromone YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YMR038C LYS7 copper chaperone for superoxide dismutase SOD1P YMR052W FAR3 involved in pheromone-mediated cell cycle arrest YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YMR058W FET3 cell surface ferroxidase, high affinity YMR177W MMT1 mitochondrial gene involved in iron uptake YMR243C ZRC1 zinc- and cadmium resistance protein YMR301C ATM1 ATP-binding cassette transporter protein, mitochondrial YMR319C FET4 low affinity Fe(II) iron transport protein YNL027W CRZ1 calcineurin responsive zinc-finger YNL053W MSG5 dual-specifity protein phosphatase YNL098C RAS2 GTP-binding protein YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YNL259C ATX1 antioxidant protein and metal homeostasis factor YNL291C MID1 involved in Ca2+ influx during mating YNL325C FIG4 weak similarity to inositol phosphatase YNR013C PHO91 similarity to PHO87P and PHO90P YNR031C SSK2 MAP kinase kinase kinase of the high osmolarity signal transduction pathway YNR060W FRE4 strong similarity to FRE2P, and similarity to FRE1P YOL110W SHR5 RAS suppressor YOL122C SMF1 manganese transporter YOL130W ALR1 divalent cation transporter YOL152W FRE7 similarity to FRE1P and FRE2P YOR031W CRS5 suppressor of cup1 deletion, metallothionein-like protein YOR079C ATX2 multicopy suppressor of SOD-linked defects YOR101W RAS1 GTP-binding protein YOR153W PDR5 pleiotropic drug resistance protein YOR176W HEM15 ferrochelatase precursor YOR208W PTP2 protein-tyrosine-phosphatase YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR316C COT1 cobalt accumulation protein YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YOR381W FRE3 strong similarity to ferric reductase FRE2P YOR384W FRE5 strong similarity to ferric reductase FRE2P YPL036W PMA2 H+-transporting P-type ATPase, minor isoform, plasma membrane YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL084W BRO1 required for normal response to nutrient limitation YPL106C SSE1 heat shock protein of HSP70 family YPL161C BEM4 bud emergence protein YPL177C CUP9 involved in copper homeostasis repression of protein import YPL203W TPK2 cAMP-dependent protein kinase 2, catalytic chain YPL224C MMT2 mitochondrial iron transporter YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPR003C YPR003C similarity to sulphate transporter proteins YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar YPR067W ISA2 mitochondrial protein required for iron metabolism YPR124W CTR1 copper transport protein Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 ionic homeostasis (127 ORFs) 13.01 127 YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBR024W SCO2 involved in stability of COX1P and COX2P YBR037C SCO1 involved in stabilization of COX1P and COX2P YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YBR207W FTH1 similarity to Iron permease FTR1P (YER145c) YBR235W YBR235W similarity to bumetanide-sensitive Na-K-Cl cotransport protein YBR290W BSD2 metal homeostasis protein YBR294W SUL1 high-affinity sulfate transport protein YBR295W PCA1 P-type Cu2+-transporting ATPase YBR296C PHO89 Na+-coupled phosphate transport protein, high affinity YCL017C NFS1 regulates Iron-Sulfur cluster proteins, cellular Iron uptake, andIron distribution YCL037C SRO9 La motif-containing proteins that modulate mRNA translation YCR021C HSP30 heat shock protein YCR024C-A PMP1 H+-ATPase subunit, plasma membrane YCR037C PHO87 member of the phosphate permease family YCR044C PER1 involved in manganese homeostasis YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL120W YFH1 regulates mitochondrial iron accumulation YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDR011W SNQ2 multidrug resistance protein YDR038C ENA5 P-type ATPase involved in Na+ efflux YDR039C ENA2 P-type ATPase involved in Na+ efflux YDR040C ENA1 P-type ATPase involved in Na+ and Li+ efflux YDR182W CDC1 cell division control protein YDR184C ATC1 binds Aip3p YDR270W CCC2 probable copper-transporting ATPase YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR456W NHX1 NA+-H+ antiporter YDR506C YDR506C similarity to FET3, YFL041w and F.floriforme diphenol oxidase YDR515W SLF1 La motif-containing proteins that modulate mRNA translation YEL017C-A PMP2 H+-ATPase subunit, plasma membrane YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL031W SPF1 P-type ATPase YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YER145C FTR1 iron permease that mediates high-affinity iron uptake YFL041W FET5 multicopy oxidase YFL050C ALR2 divalent cation transprter YGL006W PMC1 Ca2+-transporting P-type ATPase YGL008C PMA1 H+-transporting P-type ATPase, major isoform, plasma membrane YGL071W RCS1 iron-regulated transcriptional repressor YGL096W TOS8 similarity to copper homeostasis protein CUP9P YGL160W YGL160W similarity to hypothetical protein YLR047c and FRE2P YGL166W CUP2 copper-dependent transcription factor YGL167C PMR1 Ca2+-transporting P-type ATPase YGL255W ZRT1 high-affinity zinc transport protein YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YGR142W BTN2 Gene/protein whose expression is elevated in a btn1 minus/Btn1p lacking yeast strain YGR191W HIP1 histidine permease YGR217W CCH1 calcium channel protein YHL016C DUR3 urea transport protein YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YHR175W CTR2 copper transport protein YJL093C TOK1 outward-rectifier potassium channel YJL094C KHA1 K+/H+ exchanger YJL117W PHO86 inorganic phospate transporter YJL129C TRK1 potassium transport protein TRK1P, high-affinity YJL198W PHO90 low affinity phosphate transporter YJR040W GEF1 voltage-gated chloride channel protein YJR049C UTR1 associated with ferric reductase activity YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YJR126C YJR126C similarity to human prostate-specific membrane antigen and transferrin receptor protein YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL040C NFU1 iron homeostasis YKL064W MNR2 overexpression overcomes manganese toxicity YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL134C OCT1 mitochondrial intermediate peptidase YKL159C RCN1 inhibitor of calcineurin YKL190W CNB1 calcineurin B, regulatory subunit YKL220C FRE2 ferric (and cupric) reductase YLL009C COX17 interacts genetically with SCO1 and SCO2 in cytochrome oxidase assembly YLL027W ISA1 mitochondrial protein required for normal iron metabolism YLL051C FRE6 strong similarity to ferric reductase FRE2P YLR034C SMF3 strong similarity to SMF2 protein and S.pombe hypothetical protein YLR092W SUL2 sulfate transporter YLR109W AHP1 Alkyl hydroperoxide reductase YLR130C ZRT2 low affininty zinc transporter YLR138W NHA1 putative Na+/H+ antiporter YLR214W FRE1 ferric (and cupric) reductase YLR220W CCC1 involved in calcium regulation YLR295C ATP14 F1F0-ATPase complex, subunit h YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR369W SSQ1 mitochondrial heat shock protein 70 YLR411W CTR3 copper transport protein YLR433C CNA1 calcineurin B, catalytic subunit YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YMR038C LYS7 copper chaperone for superoxide dismutase SOD1P YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YMR058W FET3 cell surface ferroxidase, high affinity YMR177W MMT1 mitochondrial gene involved in iron uptake YMR243C ZRC1 zinc- and cadmium resistance protein YMR301C ATM1 ATP-binding cassette transporter protein, mitochondrial YMR319C FET4 low affinity Fe(II) iron transport protein YNL027W CRZ1 calcineurin responsive zinc-finger YNL259C ATX1 antioxidant protein and metal homeostasis factor YNL291C MID1 involved in Ca2+ influx during mating YNR013C PHO91 similarity to PHO87P and PHO90P YNR060W FRE4 strong similarity to FRE2P, and similarity to FRE1P YOL122C SMF1 manganese transporter YOL130W ALR1 divalent cation transporter YOL152W FRE7 similarity to FRE1P and FRE2P YOR031W CRS5 suppressor of cup1 deletion, metallothionein-like protein YOR079C ATX2 multicopy suppressor of SOD-linked defects YOR153W PDR5 pleiotropic drug resistance protein YOR176W HEM15 ferrochelatase precursor YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR316C COT1 cobalt accumulation protein YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YOR381W FRE3 strong similarity to ferric reductase FRE2P YOR384W FRE5 strong similarity to ferric reductase FRE2P YPL036W PMA2 H+-transporting P-type ATPase, minor isoform, plasma membrane YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL177C CUP9 involved in copper homeostasis repression of protein import YPL224C MMT2 mitochondrial iron transporter YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPR003C YPR003C similarity to sulphate transporter proteins YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar YPR067W ISA2 mitochondrial protein required for iron metabolism YPR124W CTR1 copper transport protein Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 homeostasis of cations (117 ORFs) 13.01.01 117 YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBR024W SCO2 involved in stability of COX1P and COX2P YBR037C SCO1 involved in stabilization of COX1P and COX2P YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YBR207W FTH1 similarity to Iron permease FTR1P (YER145c) YBR235W YBR235W similarity to bumetanide-sensitive Na-K-Cl cotransport protein YBR290W BSD2 metal homeostasis protein YBR295W PCA1 P-type Cu2+-transporting ATPase YBR296C PHO89 Na+-coupled phosphate transport protein, high affinity YCL017C NFS1 regulates Iron-Sulfur cluster proteins, cellular Iron uptake, andIron distribution YCL037C SRO9 La motif-containing proteins that modulate mRNA translation YCR021C HSP30 heat shock protein YCR024C-A PMP1 H+-ATPase subunit, plasma membrane YCR044C PER1 involved in manganese homeostasis YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL120W YFH1 regulates mitochondrial iron accumulation YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDR011W SNQ2 multidrug resistance protein YDR038C ENA5 P-type ATPase involved in Na+ efflux YDR039C ENA2 P-type ATPase involved in Na+ efflux YDR040C ENA1 P-type ATPase involved in Na+ and Li+ efflux YDR182W CDC1 cell division control protein YDR184C ATC1 binds Aip3p YDR270W CCC2 probable copper-transporting ATPase YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR456W NHX1 NA+-H+ antiporter YDR506C YDR506C similarity to FET3, YFL041w and F.floriforme diphenol oxidase YDR515W SLF1 La motif-containing proteins that modulate mRNA translation YEL017C-A PMP2 H+-ATPase subunit, plasma membrane YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL031W SPF1 P-type ATPase YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YER145C FTR1 iron permease that mediates high-affinity iron uptake YFL041W FET5 multicopy oxidase YFL050C ALR2 divalent cation transprter YGL006W PMC1 Ca2+-transporting P-type ATPase YGL008C PMA1 H+-transporting P-type ATPase, major isoform, plasma membrane YGL071W RCS1 iron-regulated transcriptional repressor YGL096W TOS8 similarity to copper homeostasis protein CUP9P YGL160W YGL160W similarity to hypothetical protein YLR047c and FRE2P YGL166W CUP2 copper-dependent transcription factor YGL167C PMR1 Ca2+-transporting P-type ATPase YGL255W ZRT1 high-affinity zinc transport protein YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YGR191W HIP1 histidine permease YGR217W CCH1 calcium channel protein YHL016C DUR3 urea transport protein YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YHR175W CTR2 copper transport protein YJL093C TOK1 outward-rectifier potassium channel YJL094C KHA1 K+/H+ exchanger YJL129C TRK1 potassium transport protein TRK1P, high-affinity YJR049C UTR1 associated with ferric reductase activity YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YJR126C YJR126C similarity to human prostate-specific membrane antigen and transferrin receptor protein YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL040C NFU1 iron homeostasis YKL064W MNR2 overexpression overcomes manganese toxicity YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL134C OCT1 mitochondrial intermediate peptidase YKL159C RCN1 inhibitor of calcineurin YKL190W CNB1 calcineurin B, regulatory subunit YKL220C FRE2 ferric (and cupric) reductase YLL009C COX17 interacts genetically with SCO1 and SCO2 in cytochrome oxidase assembly YLL027W ISA1 mitochondrial protein required for normal iron metabolism YLL051C FRE6 strong similarity to ferric reductase FRE2P YLR034C SMF3 strong similarity to SMF2 protein and S.pombe hypothetical protein YLR109W AHP1 Alkyl hydroperoxide reductase YLR130C ZRT2 low affininty zinc transporter YLR138W NHA1 putative Na+/H+ antiporter YLR214W FRE1 ferric (and cupric) reductase YLR220W CCC1 involved in calcium regulation YLR295C ATP14 F1F0-ATPase complex, subunit h YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR369W SSQ1 mitochondrial heat shock protein 70 YLR411W CTR3 copper transport protein YLR433C CNA1 calcineurin B, catalytic subunit YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YMR038C LYS7 copper chaperone for superoxide dismutase SOD1P YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YMR058W FET3 cell surface ferroxidase, high affinity YMR177W MMT1 mitochondrial gene involved in iron uptake YMR243C ZRC1 zinc- and cadmium resistance protein YMR301C ATM1 ATP-binding cassette transporter protein, mitochondrial YMR319C FET4 low affinity Fe(II) iron transport protein YNL027W CRZ1 calcineurin responsive zinc-finger YNL259C ATX1 antioxidant protein and metal homeostasis factor YNL291C MID1 involved in Ca2+ influx during mating YNR060W FRE4 strong similarity to FRE2P, and similarity to FRE1P YOL122C SMF1 manganese transporter YOL130W ALR1 divalent cation transporter YOL152W FRE7 similarity to FRE1P and FRE2P YOR031W CRS5 suppressor of cup1 deletion, metallothionein-like protein YOR079C ATX2 multicopy suppressor of SOD-linked defects YOR153W PDR5 pleiotropic drug resistance protein YOR176W HEM15 ferrochelatase precursor YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR316C COT1 cobalt accumulation protein YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YOR381W FRE3 strong similarity to ferric reductase FRE2P YOR384W FRE5 strong similarity to ferric reductase FRE2P YPL036W PMA2 H+-transporting P-type ATPase, minor isoform, plasma membrane YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL177C CUP9 involved in copper homeostasis repression of protein import YPL224C MMT2 mitochondrial iron transporter YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar YPR067W ISA2 mitochondrial protein required for iron metabolism YPR124W CTR1 copper transport protein Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 homeostasis of metal ions (Na, K, Ca etc.) (62 ORFs) 13.01.01.01 62 YBR024W SCO2 involved in stability of COX1P and COX2P YBR037C SCO1 involved in stabilization of COX1P and COX2P YBR207W FTH1 similarity to Iron permease FTR1P (YER145c) YBR290W BSD2 metal homeostasis protein YBR295W PCA1 P-type Cu2+-transporting ATPase YCL017C NFS1 regulates Iron-Sulfur cluster proteins, cellular Iron uptake, andIron distribution YCL037C SRO9 La motif-containing proteins that modulate mRNA translation YCR044C PER1 involved in manganese homeostasis YDL120W YFH1 regulates mitochondrial iron accumulation YDR011W SNQ2 multidrug resistance protein YDR182W CDC1 cell division control protein YDR270W CCC2 probable copper-transporting ATPase YDR506C YDR506C similarity to FET3, YFL041w and F.floriforme diphenol oxidase YDR515W SLF1 La motif-containing proteins that modulate mRNA translation YER145C FTR1 iron permease that mediates high-affinity iron uptake YFL041W FET5 multicopy oxidase YFL050C ALR2 divalent cation transprter YGL071W RCS1 iron-regulated transcriptional repressor YGL096W TOS8 similarity to copper homeostasis protein CUP9P YGL160W YGL160W similarity to hypothetical protein YLR047c and FRE2P YGL166W CUP2 copper-dependent transcription factor YGL255W ZRT1 high-affinity zinc transport protein YGR191W HIP1 histidine permease YHR175W CTR2 copper transport protein YJR049C UTR1 associated with ferric reductase activity YJR126C YJR126C similarity to human prostate-specific membrane antigen and transferrin receptor protein YKL040C NFU1 iron homeostasis YKL064W MNR2 overexpression overcomes manganese toxicity YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL134C OCT1 mitochondrial intermediate peptidase YKL220C FRE2 ferric (and cupric) reductase YLL009C COX17 interacts genetically with SCO1 and SCO2 in cytochrome oxidase assembly YLL027W ISA1 mitochondrial protein required for normal iron metabolism YLL051C FRE6 strong similarity to ferric reductase FRE2P YLR034C SMF3 strong similarity to SMF2 protein and S.pombe hypothetical protein YLR109W AHP1 Alkyl hydroperoxide reductase YLR130C ZRT2 low affininty zinc transporter YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR369W SSQ1 mitochondrial heat shock protein 70 YLR411W CTR3 copper transport protein YMR038C LYS7 copper chaperone for superoxide dismutase SOD1P YMR058W FET3 cell surface ferroxidase, high affinity YMR177W MMT1 mitochondrial gene involved in iron uptake YMR243C ZRC1 zinc- and cadmium resistance protein YMR301C ATM1 ATP-binding cassette transporter protein, mitochondrial YMR319C FET4 low affinity Fe(II) iron transport protein YNL259C ATX1 antioxidant protein and metal homeostasis factor YNR060W FRE4 strong similarity to FRE2P, and similarity to FRE1P YOL122C SMF1 manganese transporter YOL130W ALR1 divalent cation transporter YOL152W FRE7 similarity to FRE1P and FRE2P YOR031W CRS5 suppressor of cup1 deletion, metallothionein-like protein YOR079C ATX2 multicopy suppressor of SOD-linked defects YOR153W PDR5 pleiotropic drug resistance protein YOR176W HEM15 ferrochelatase precursor YOR316C COT1 cobalt accumulation protein YOR381W FRE3 strong similarity to ferric reductase FRE2P YOR384W FRE5 strong similarity to ferric reductase FRE2P YPL177C CUP9 involved in copper homeostasis repression of protein import YPL224C MMT2 mitochondrial iron transporter YPR067W ISA2 mitochondrial protein required for iron metabolism YPR124W CTR1 copper transport protein homeostasis of protons (36 ORFs) 13.01.01.03 36 YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YCR021C HSP30 heat shock protein YCR024C-A PMP1 H+-ATPase subunit, plasma membrane YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR456W NHX1 NA+-H+ antiporter YEL017C-A PMP2 H+-ATPase subunit, plasma membrane YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YGL008C PMA1 H+-transporting P-type ATPase, major isoform, plasma membrane YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YJL094C KHA1 K+/H+ exchanger YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL159C RCN1 inhibitor of calcineurin YLR138W NHA1 putative Na+/H+ antiporter YLR295C ATP14 F1F0-ATPase complex, subunit h YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YPL036W PMA2 H+-transporting P-type ATPase, minor isoform, plasma membrane YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 homeostasis of other cations (23 ORFs) 13.01.01.99 23 YBR235W YBR235W similarity to bumetanide-sensitive Na-K-Cl cotransport protein YBR296C PHO89 Na+-coupled phosphate transport protein, high affinity YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDR038C ENA5 P-type ATPase involved in Na+ efflux YDR039C ENA2 P-type ATPase involved in Na+ efflux YDR040C ENA1 P-type ATPase involved in Na+ and Li+ efflux YDR456W NHX1 NA+-H+ antiporter YEL031W SPF1 P-type ATPase YGL006W PMC1 Ca2+-transporting P-type ATPase YGL167C PMR1 Ca2+-transporting P-type ATPase YGR217W CCH1 calcium channel protein YHL016C DUR3 urea transport protein YJL093C TOK1 outward-rectifier potassium channel YJL094C KHA1 K+/H+ exchanger YJL129C TRK1 potassium transport protein TRK1P, high-affinity YKL159C RCN1 inhibitor of calcineurin YKL190W CNB1 calcineurin B, regulatory subunit YLR138W NHA1 putative Na+/H+ antiporter YLR214W FRE1 ferric (and cupric) reductase YLR220W CCC1 involved in calcium regulation YLR433C CNA1 calcineurin B, catalytic subunit YNL027W CRZ1 calcineurin responsive zinc-finger YNL291C MID1 involved in Ca2+ influx during mating homeostasis of anions (13 ORFs) 13.01.03 13 YBR235W YBR235W similarity to bumetanide-sensitive Na-K-Cl cotransport protein YBR294W SUL1 high-affinity sulfate transport protein YBR296C PHO89 Na+-coupled phosphate transport protein, high affinity YCR037C PHO87 member of the phosphate permease family YHL016C DUR3 urea transport protein YJL117W PHO86 inorganic phospate transporter YJL198W PHO90 low affinity phosphate transporter YJR040W GEF1 voltage-gated chloride channel protein YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YLR092W SUL2 sulfate transporter YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YNR013C PHO91 similarity to PHO87P and PHO90P YPR003C YPR003C similarity to sulphate transporter proteins homeostasis of sulfates (3 ORFs) 13.01.03.01 3 YBR294W SUL1 high-affinity sulfate transport protein YLR092W SUL2 sulfate transporter YPR003C YPR003C similarity to sulphate transporter proteins homeostasis of phosphate (7 ORFs) 13.01.03.03 7 YBR296C PHO89 Na+-coupled phosphate transport protein, high affinity YCR037C PHO87 member of the phosphate permease family YJL117W PHO86 inorganic phospate transporter YJL198W PHO90 low affinity phosphate transporter YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YNR013C PHO91 similarity to PHO87P and PHO90P homeostasis of chloride (2 ORFs) 13.01.03.05 2 YBR235W YBR235W similarity to bumetanide-sensitive Na-K-Cl cotransport protein YJR040W GEF1 voltage-gated chloride channel protein homeostasis of other anions (1 ORF) 13.01.03.99 1 YHL016C DUR3 urea transport protein cellular sensing and response (73 ORFs) 13.11 73 YAL041W CDC24 GTP/GDP exchange factor for CDC42P YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBR129C OPY1 pheromone resistant yeast 1 YBR140C IRA1 inhibitory regulator protein of the ras-cyclic AMP pathway YBR195C MSI1 chromatin assembly complex, subunit p50 YCL027W FUS1 cell fusion protein YCL032W STE50 pheromone response pathway protein YCR073C SSK22 MAP kinase kinase kinase YDL006W PTC1 protein serine/threonine phosphatase 2c YDL022W GPD1 glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic YDL035C GPR1 G-protein coupled receptor YDL159W STE7 ser/thr/tyr protein kinase of MAP kinase kinase family YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL235C YPD1 phosphorelay intermediate between SLN1P and SSK1P YDR069C DOA4 ubiquitin-specific protease YDR103W STE5 pheromone signal transduction pathway protein YDR183W PLP1 Phosducin homologue likely to be involved in regulation of pheromone response YDR264C AKR1 ankyrin repeat-containing protein YDR309C GIC2 CDC42 GTPase-binding protein YDR461W MFA1 mating pheromone a-factor 1 YER020W GPA2 guanine nucleotide-binding regulatory protein YER118C SHO1 involved in the HOG1 high-osmolarity signal transduction pathway YFL014W HSP12 heat shock protein YFL026W STE2 pheromone alpha-factor receptor YGL178W MPT5 multicopy suppressor of POP2 YGR040W KSS1 ser/thr protein kinase of the MAP kinase family YGR238C KEL2 involved in cell fusion and morphogenesis YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR061C GIC1 CDC42 GTPase-binding protein YHR084W STE12 transcriptional activator YHR146W CRP1 similarity to pheromone-response G-protein MDG1P YHR158C KEL1 involved in cell fusion and morphology YHR205W SCH9 serine/threonine protein kinase involved in stress response and nutrient-sensing signaling pathway YIL047C SYG1 member of the major facilitator superfamily YIL119C RPI1 negative regulator of ras-cAMP pathway YIL147C SLN1 two-component signal transducer YIR026C YVH1 protein tyrosine phosphatase YJL005W CYR1 adenylate cyclase YJL128C PBS2 tyrosine protein kinase of the MAP kinase kinase family YJL156C SSY5 part of an extracellular amino acid sensor YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJR059W PTK2 involved in polyamine uptake YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL178C STE3 pheromone a-factor receptor YKL185W ASH1 negative regulator of HO transcription YKL198C PTK1 polyamine transport enhancing protein YLL016W SDC25 GDP/GTP exchange factor (GEF) YLL021W SPA2 involved in cell polarity YLR006C SSK1 two-component signal transducer YLR113W HOG1 ser/thr protein kinase of MAP kinase (MAPK) family YLR178C TFS1 CDC25-dependent nutrient- and ammonia-response cell-cycle regulator YLR229C CDC42 GTP-binding protein of RAS superfamily YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR336C SGD1 involved in HOG pathway YLR362W STE11 ser/thr protein kinase of the MEKK family YLR452C SST2 involved in desensitization to alpha-factor pheromone YMR052W FAR3 involved in pheromone-mediated cell cycle arrest YNL053W MSG5 dual-specifity protein phosphatase YNL098C RAS2 GTP-binding protein YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YNL325C FIG4 weak similarity to inositol phosphatase YNR031C SSK2 MAP kinase kinase kinase of the high osmolarity signal transduction pathway YOL110W SHR5 RAS suppressor YOR101W RAS1 GTP-binding protein YOR208W PTP2 protein-tyrosine-phosphatase YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YPL084W BRO1 required for normal response to nutrient limitation YPL106C SSE1 heat shock protein of HSP70 family YPL161C BEM4 bud emergence protein YPL203W TPK2 cAMP-dependent protein kinase 2, catalytic chain chemoperception and response (73 ORFs) 13.11.03 73 YAL041W CDC24 GTP/GDP exchange factor for CDC42P YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBR129C OPY1 pheromone resistant yeast 1 YBR140C IRA1 inhibitory regulator protein of the ras-cyclic AMP pathway YBR195C MSI1 chromatin assembly complex, subunit p50 YCL027W FUS1 cell fusion protein YCL032W STE50 pheromone response pathway protein YCR073C SSK22 MAP kinase kinase kinase YDL006W PTC1 protein serine/threonine phosphatase 2c YDL022W GPD1 glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic YDL035C GPR1 G-protein coupled receptor YDL159W STE7 ser/thr/tyr protein kinase of MAP kinase kinase family YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL235C YPD1 phosphorelay intermediate between SLN1P and SSK1P YDR069C DOA4 ubiquitin-specific protease YDR103W STE5 pheromone signal transduction pathway protein YDR183W PLP1 Phosducin homologue likely to be involved in regulation of pheromone response YDR264C AKR1 ankyrin repeat-containing protein YDR309C GIC2 CDC42 GTPase-binding protein YDR461W MFA1 mating pheromone a-factor 1 YER020W GPA2 guanine nucleotide-binding regulatory protein YER118C SHO1 involved in the HOG1 high-osmolarity signal transduction pathway YFL014W HSP12 heat shock protein YFL026W STE2 pheromone alpha-factor receptor YGL178W MPT5 multicopy suppressor of POP2 YGR040W KSS1 ser/thr protein kinase of the MAP kinase family YGR238C KEL2 involved in cell fusion and morphogenesis YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR061C GIC1 CDC42 GTPase-binding protein YHR084W STE12 transcriptional activator YHR146W CRP1 similarity to pheromone-response G-protein MDG1P YHR158C KEL1 involved in cell fusion and morphology YHR205W SCH9 serine/threonine protein kinase involved in stress response and nutrient-sensing signaling pathway YIL047C SYG1 member of the major facilitator superfamily YIL119C RPI1 negative regulator of ras-cAMP pathway YIL147C SLN1 two-component signal transducer YIR026C YVH1 protein tyrosine phosphatase YJL005W CYR1 adenylate cyclase YJL128C PBS2 tyrosine protein kinase of the MAP kinase kinase family YJL156C SSY5 part of an extracellular amino acid sensor YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJR059W PTK2 involved in polyamine uptake YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL178C STE3 pheromone a-factor receptor YKL185W ASH1 negative regulator of HO transcription YKL198C PTK1 polyamine transport enhancing protein YLL016W SDC25 GDP/GTP exchange factor (GEF) YLL021W SPA2 involved in cell polarity YLR006C SSK1 two-component signal transducer YLR113W HOG1 ser/thr protein kinase of MAP kinase (MAPK) family YLR178C TFS1 CDC25-dependent nutrient- and ammonia-response cell-cycle regulator YLR229C CDC42 GTP-binding protein of RAS superfamily YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR336C SGD1 involved in HOG pathway YLR362W STE11 ser/thr protein kinase of the MEKK family YLR452C SST2 involved in desensitization to alpha-factor pheromone YMR052W FAR3 involved in pheromone-mediated cell cycle arrest YNL053W MSG5 dual-specifity protein phosphatase YNL098C RAS2 GTP-binding protein YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YNL325C FIG4 weak similarity to inositol phosphatase YNR031C SSK2 MAP kinase kinase kinase of the high osmolarity signal transduction pathway YOL110W SHR5 RAS suppressor YOR101W RAS1 GTP-binding protein YOR208W PTP2 protein-tyrosine-phosphatase YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YPL084W BRO1 required for normal response to nutrient limitation YPL106C SSE1 heat shock protein of HSP70 family YPL161C BEM4 bud emergence protein YPL203W TPK2 cAMP-dependent protein kinase 2, catalytic chain perception of nutrients and nutritional adaptation (25 ORFs) 13.11.03.01 25 YBR140C IRA1 inhibitory regulator protein of the ras-cyclic AMP pathway YBR195C MSI1 chromatin assembly complex, subunit p50 YDL035C GPR1 G-protein coupled receptor YDL159W STE7 ser/thr/tyr protein kinase of MAP kinase kinase family YDL194W SNF3 high-affinity glucose transporter/regulatory protein YER020W GPA2 guanine nucleotide-binding regulatory protein YHR084W STE12 transcriptional activator YHR205W SCH9 serine/threonine protein kinase involved in stress response and nutrient-sensing signaling pathway YIL119C RPI1 negative regulator of ras-cAMP pathway YIR026C YVH1 protein tyrosine phosphatase YJL005W CYR1 adenylate cyclase YJL156C SSY5 part of an extracellular amino acid sensor YJR059W PTK2 involved in polyamine uptake YKL198C PTK1 polyamine transport enhancing protein YLL016W SDC25 GDP/GTP exchange factor (GEF) YLR178C TFS1 CDC25-dependent nutrient- and ammonia-response cell-cycle regulator YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR362W STE11 ser/thr protein kinase of the MEKK family YNL098C RAS2 GTP-binding protein YOL110W SHR5 RAS suppressor YOR101W RAS1 GTP-binding protein YOR208W PTP2 protein-tyrosine-phosphatase YPL084W BRO1 required for normal response to nutrient limitation YPL106C SSE1 heat shock protein of HSP70 family YPL203W TPK2 cAMP-dependent protein kinase 2, catalytic chain pheromone response (37 ORFs) 13.11.03.07 37 YAL041W CDC24 GTP/GDP exchange factor for CDC42P YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBR129C OPY1 pheromone resistant yeast 1 YCL027W FUS1 cell fusion protein YCL032W STE50 pheromone response pathway protein YDL159W STE7 ser/thr/tyr protein kinase of MAP kinase kinase family YDR103W STE5 pheromone signal transduction pathway protein YDR183W PLP1 Phosducin homologue likely to be involved in regulation of pheromone response YDR264C AKR1 ankyrin repeat-containing protein YDR309C GIC2 CDC42 GTPase-binding protein YDR461W MFA1 mating pheromone a-factor 1 YER020W GPA2 guanine nucleotide-binding regulatory protein YFL026W STE2 pheromone alpha-factor receptor YGL178W MPT5 multicopy suppressor of POP2 YGR040W KSS1 ser/thr protein kinase of the MAP kinase family YGR238C KEL2 involved in cell fusion and morphogenesis YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR061C GIC1 CDC42 GTPase-binding protein YHR084W STE12 transcriptional activator YHR146W CRP1 similarity to pheromone-response G-protein MDG1P YHR158C KEL1 involved in cell fusion and morphology YIL047C SYG1 member of the major facilitator superfamily YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YKL178C STE3 pheromone a-factor receptor YKL185W ASH1 negative regulator of HO transcription YLL021W SPA2 involved in cell polarity YLR229C CDC42 GTP-binding protein of RAS superfamily YLR362W STE11 ser/thr protein kinase of the MEKK family YLR452C SST2 involved in desensitization to alpha-factor pheromone YMR052W FAR3 involved in pheromone-mediated cell cycle arrest YNL053W MSG5 dual-specifity protein phosphatase YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YNL325C FIG4 weak similarity to inositol phosphatase YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YPL161C BEM4 bud emergence protein osmosensing (17 ORFs) 13.11.03.13 17 YCR073C SSK22 MAP kinase kinase kinase YDL006W PTC1 protein serine/threonine phosphatase 2c YDL022W GPD1 glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic YDL235C YPD1 phosphorelay intermediate between SLN1P and SSK1P YDR069C DOA4 ubiquitin-specific protease YER118C SHO1 involved in the HOG1 high-osmolarity signal transduction pathway YFL014W HSP12 heat shock protein YHR030C SLT2 ser/thr protein kinase of MAP kinase family YIL147C SLN1 two-component signal transducer YJL128C PBS2 tyrosine protein kinase of the MAP kinase kinase family YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YLR006C SSK1 two-component signal transducer YLR113W HOG1 ser/thr protein kinase of MAP kinase (MAPK) family YLR336C SGD1 involved in HOG pathway YLR362W STE11 ser/thr protein kinase of the MEKK family YNR031C SSK2 MAP kinase kinase kinase of the high osmolarity signal transduction pathway YOR208W PTP2 protein-tyrosine-phosphatase CELL FATE (427 ORFs) 14 427 YAL009W SPO7 meiotic protein YAL016W TPD3 ser/thr protein phosphatase 2A, regulatory chain A YAL029C MYO4 myosin heavy chain, unconventional (class V) isoform YAL040C CLN3 cyclin, G1/S-specific YAL041W CDC24 GTP/GDP exchange factor for CDC42P YAR007C RFA1 DNA replication factor A, 69 KD subunit YBL007C SLA1 cytoskeleton assembly control protein YBL015W ACH1 acetyl-CoA hydrolase YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBL028C YBL028C hypothetical protein - involved in mating-type regulation YBL052C SAS3 silencing protein YBL058W SHP1 potential regulatory subunit for GLC7P YBL066C SEF1 putative transcription factor YBL085W BOI1 BEM1 protein-binding protein YBL105C PKC1 ser/thr protein kinase YBL106C SRO77 polarized exocytosis by regulating SNARE function YBR015C MNN2 type II membrane protein YBR023C CHS3 chitin synthase III YBR038W CHS2 chitin synthase II YBR040W FIG1 required for efficient mating YBR045C GIP1 GLC7-interacting protein YBR057C MUM2 meiotic protein YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR078W ECM33 involved in cell wall biogenesis and architecture YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR083W TEC1 Ty transcription activator YBR089C-A NHP6B nonhistone chromosomal protein YBR109C CMD1 calmodulin YBR130C SHE3 required for mother cell-specific expression of HO YBR148W YSW1 spore-specific protein YBR160W CDC28 cyclin-dependent protein kinase YBR161W YBR161W strong similarity to SUR1P YBR200W BEM1 bud emergence mediator YBR210W YBR210W strong similarity to D.melanogaster cornichon protein YBR212W NGR1 glucose-repressible RNA-binding protein YBR234C ARC40 ARP2/3 protein complex subunit, 40 kilodalton YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR289W SNF5 component of SWI/SNF transcription activator complex YCL014W BUD3 budding protein YCL027W FUS1 cell fusion protein YCL029C BIK1 nuclear fusion protein YCL032W STE50 pheromone response pathway protein YCL048W YCL048W strong similarity to sporulation-specific protein SPS2P YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCL066W HMLALPHA1 mating type regulatory protein, silenced copy at HML YCL067C HMLALPHA2 mating type regulatory protein, silenced copy at HML YCR002C CDC10 cell division control protein YCR009C RVS161 similarity to human amphiphysin and RVS167P YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR038C BUD5 GDP/GTP exchange factor for RSR1P/Bud1p YCR039C MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040W MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCR048W ARE1 acyl-CoA sterol acyltransferase YCR057C PWP2 periodic tryptophan protein YCR086W CSM1 involved in nuclear migration YCR088W ABP1 actin-binding protein YCR089W FIG2 required for efficient mating YCR093W CDC39 nuclear protein YCR096C A2 mating type regulatory protein, silenced copy at HMR locus YCR097W A1 mating type regulatory protein, silenced copy at HMR locus YDL006W PTC1 protein serine/threonine phosphatase 2c YDL029W ARP2 actin-like protein YDL035C GPR1 G-protein coupled receptor YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL047W SIT4 ser/thr protein phosphatase YDL116W NUP84 nuclear pore protein YDL134C PPH21 protein ser/thr phosphatase PP2A-1 YDL135C RDI1 rho GDP dissociation inhibitor with activity toward RHO1P YDL159W STE7 ser/thr/tyr protein kinase of MAP kinase kinase family YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL224C WHI4 strong similarity to WHI3 protein YDL225W SHS1 septin YDL227C HO homothallic switching endonuclease YDL240W LRG1 GTPase-activating protein of the rho/rac family YDR004W RAD57 DNA repair protein YDR055W PST1 strong similarity to SPS2 protein YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR069C DOA4 ubiquitin-specific protease YDR073W SNF11 component of SWI/SNF transcription activator complex YDR075W PPH3 protein ser/thr phosphatase YDR076W RAD55 DNA repair protein YDR085C AFR1 involved in morphogenesis of the mating projection YDR099W BMH2 suppressor of clathrin deficiency YDR103W STE5 pheromone signal transduction pathway protein YDR104C SPO71 protein involved in spore wall formation YDR108W GSG1 sporulation specific protein YDR129C SAC6 actin filament bundling protein, fimbrin YDR137W RGP1 reduced growth phenotype protein YDR143C SAN1 mating-type regulation protein YDR146C SWI5 transcription factor YDR151C CTH1 strong similarity to CCCH zinc finger protein TIS11P YDR173C ARG82 arginine metabolism transcription factor YDR177W UBC1 E2 ubiquitin-conjugating enzyme YDR182W CDC1 cell division control protein YDR191W HST4 member of the SIR2P family of putative NAD-dependent histone deacetylases YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR218C SPR28 septin-related sporulation protein YDR227W SIR4 silencing regulatory and DNA-repair protein YDR245W MNN10 subunit of mannosyltransferase complex YDR251W PAM1 coiled-coil protein multicopy suppressor of loss of PP2A YDR260C SWM1 developmentally regulated gene, is required for spore wall assembly YDR261C EXG2 exo-beta-1,3-glucanase minor isoform YDR264C AKR1 ankyrin repeat-containing protein YDR284C DPP1 diacylglycerol pyrophosphate phosphatase YDR293C SSD1 involved in the tolerance to high concentration of Ca2+ YDR299W BFR2 involved in protein transport steps at the Brefeldin A blocks YDR309C GIC2 CDC42 GTPase-binding protein YDR312W SSF2 protein with a potential role in mating YDR335W MSN5 multicopy supressor of SNF1 mutation YDR351W SBE2 bud growth protein YDR363W-A SEM1 regulator of exocytosis and pseudohyphal differentiation YDR388W RVS167 reduced viability upon starvation protein YDR392W SPT3 general transcriptional adaptor or co-activator YDR402C DIT2 cytochrome P450 56 YDR403W DIT1 spore wall maturation protein YDR461W MFA1 mating pheromone a-factor 1 YDR480W DIG2 MAP kinase-associated protein, down-regulator of invasive growth and mating YDR507C GIN4 ser/thr protein kinase YDR522C SPS2 sporulation-specific protein YDR523C SPS1 ser/thr protein kinase YER008C SEC3 component of exocyst complex YER012W PRE1 20S proteasome subunit C11(beta4) YER020W GPA2 guanine nucleotide-binding regulatory protein YER044C-A MEI4 meiosis-specific protein YER068W MOT2 transcriptional repressor YER072W VTC1 Negative Regulator of Cdc Fourty two (CDC42) YER075C PTP3 protein tyrosine phosphatase YER095W RAD51 DNA repair protein YER096W SHC1 sporulation specific protein YER100W UBC6 E2 ubiquitin-conjugating enzyme YER109C FLO8 required for diploid filamentous growth YER114C BOI2 budding protein YER115C SPR6 sporulation-specific protein YER125W RSP5 hect domain E3 ubiquitin-protein ligase YER132C PMD1 negative regulator of early meiotic expression YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER149C PEA2 involved in oriented growth toward mating partner YER155C BEM2 GTPase-activating protein YER170W ADK2 adenylate kinase, mitochondrial YER177W BMH1 14-3-3 protein involved in rapamycin-sensitive signalling YFL005W SEC4 GTP-binding protein of the ras superfamily YFL009W CDC4 cell division control protein YFL026W STE2 pheromone alpha-factor receptor YFL039C ACT1 actin YFL047W RGD2 GTPase activating protein YFR014C CMK1 Ca2+/calmodulin-dependent ser/thr protein kinase type I YFR040W SAP155 SIT4P-associated protein YGL032C AGA2 a-agglutinin binding subunit YGL054C ERV14 ER-derived Vesicles YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL089C MF(ALPHA)2 mating pheromone alpha-2 factor YGL090W LIF1 DNA ligase IV interacting factor YGL095C VPS45 vacuolar protein sorting-associated protein YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL100W SEH1 nuclear pore protein YGL106W MLC1 MYO2P light chain YGL155W CDC43 geranylgeranyltransferase beta subunit YGL178W MPT5 multicopy suppressor of POP2 YGL180W APG1 essential for autophagocytosis YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL190C CDC55 ser/thr phosphatase 2A regulatory subunit B YGL192W IME4 positive transcription factor for IME2 YGL197W MDS3 negative regulator of early meiotic expression YGR009C SEC9 protein transport protein YGR014W MSB2 multicopy suppressor of a CDC24 bud emergence defect YGR023W MTL1 potential cell wall stres sensor YGR032W GSC2 1,3-beta-D-glucan synthase subunit YGR040W KSS1 ser/thr protein kinase of the MAP kinase family YGR041W BUD9 budding protein YGR059W SPR3 sporulation-specific septin YGR070W ROM1 GDP/GTP exchange protein for RHO1P YGR080W TWF1 twinfilin, an actin monomer sequestering protein YGR152C RSR1 GTP-binding protein YGR167W CLC1 clathrin light chain YGR214W RPS0A 40S ribosomal protein p40 homolog A YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YGR217W CCH1 calcium channel protein YGR225W AMA1 required for sporulation YGR238C KEL2 involved in cell fusion and morphogenesis YGR253C PUP2 20S proteasome subunit(alpha5) YHL003C LAG1 longevity-assurance protein YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHL024W RIM4 No sporulation YHL025W SNF6 global transcription activator YHR004C NEM1 required for nuclear morphology YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR023W MYO1 myosin-1 isoform (type II myosin) heavy chain YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR061C GIC1 CDC42 GTPase-binding protein YHR066W SSF1 mating protein YHR084W STE12 transcriptional activator YHR103W SBE22 golgi protein involved in yeast cell wall formation YHR107C CDC12 septin YHR118C ORC6 origin recognition complex, 50 KD subunit YHR119W SET1 involved in chromatin-mediated gene regulation YHR135C YCK1 casein kinase I isoform YHR139C SPS100 sporulation-specific wall maturation protein YHR146W CRP1 similarity to pheromone-response G-protein MDG1P YHR152W SPO12 sporulation protein YHR153C SPO16 sporulation protein YHR158C KEL1 involved in cell fusion and morphology YHR184W SSP1 essential for meiosis and spore formation YHR185C PFS1 similarity to S. pombe TEA1P YHR205W SCH9 serine/threonine protein kinase involved in stress response and nutrient-sensing signaling pathway YHR206W SKN7 transcription factor with similarity to HSF1P YIL015W BAR1 barrierpepsin precursor YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL034C CAP2 F-actin capping protein, beta subunit YIL047C SYG1 member of the major facilitator superfamily YIL049W DFG10 involved in filamentous growth, cell polarity, and cellular elongation YIL073C SPO22 weak similarity to mouse polycystic kidney disease-related protein YIL084C SDS3 transcriptional regulator YIL099W SGA1 sporulation specific glucan 1,4-alpha-glucosidase YIL118W RHO3 GTP-binding protein of the rho family YIL123W SIM1 involved in cell cycle regulation and aging YIL124W AYR1 1-Acyldihydroxyacetone-phosphate reductase YIL138C TPM2 tropomyosin, isoform 2 YIL140W AXL2 required for axial pattern of budding YIL159W BNR1 regulator of budding YIR006C PAN1 actin-cytoskeleton assembly protein YIR026C YVH1 protein tyrosine phosphatase YJL001W PRE3 20S proteasome subunit (beta1) YJL005W CYR1 adenylate cyclase YJL078C PRY3 strong similarity to the plant PR-1 class of pathogen related proteins YJL079C PRY1 strong similarity to the plant PR-1 class of pathogen related proteins YJL095W BCK1 ser/thr protein kinase of the MEKK family YJL098W SAP185 SIT4P-associating protein YJL106W IME2 ser/thr protein kinase YJL116C NCA3 involved in regulation of synthesis of ATP6P and Atp8p YJL146W IDS2 IME2-dependent signaling protein YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJL158C CIS3 strong similarity to PIR1P/HSP150P/PIR3P family YJL159W HSP150 member of the PIR1P/HSP150P/PIR3P family YJL160C YJL160C strong similarity to PIR1P/HSP150P/PIR3P family YJL170C ASG7 weak similarity to Helicobacter pylori endonuclease III YJL174W KRE9 cell wall synthesis protein YJL176C SWI3 transcription regulatory protein YJL212C OPT1 oligopeptide transporter specific for tetra- and pentapeptides YJR004C SAG1 alpha-agglutinin YJR032W CPR7 member of the cyclophilin family YJR042W NUP85 nuclear pore protein YJR075W HOC1 suppressor of PKC1 YJR076C CDC11 septin YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YJR089W BIR1 member of the inhibitor of apoptosis family, participate in chromosome segregation events YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR092W BUD4 budding protein YJR094C IME1 transcription factor required for sporulation YJR117W STE24 zinc metallo-protease YKL007W CAP1 F-actin capping protein alpha subunit YKL008C LAC1 protein required with LAG1P for ER-to-Golgi transport of GPI-anchored proteins YKL021C MAK11 involved in cell growth and replication of M1 dsRNA virus YKL043W PHD1 transcription factor YKL048C ELM1 ser/thr-specific protein kinase YKL079W SMY1 kinesin-related protein YKL092C BUD2 GTPase-activating protein for Bud1p/RSR1P YKL101W HSL1 ser/thr protein kinase, coupling septin ring assembly to cell cycle progression YKL104C GFA1 glucosamine--fructose-6-phosphate transaminase YKL117W SBA1 Hsp90 (Ninety) Associated Co-chaperone YKL129C MYO3 myosin type I YKL130C SHE2 required for mother cell-specific expression of HO YKL149C DBR1 lariat-debranching enzyme YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL165C MCD4 sporulation protein YKL178C STE3 pheromone a-factor receptor YKL181W PRS1 ribose-phosphate pyrophosphokinase YKL185W ASH1 negative regulator of HO transcription YKL189W HYM1 similarity to mouse hypothetical calcium-binding protein and D.melanogaster Mo25 gene YKL190W CNB1 calcineurin B, regulatory subunit YKL203C TOR2 phosphatidylinositol 3-kinase YKL209C STE6 ATP-binding cassette transporter protein YKR028W SAP190 SIT4P-associated protein YKR031C SPO14 phospholipase D YKR042W UTH1 involved in the aging process YKR048C NAP1 nucleosome assembly protein I YKR055W RHO4 GTP-binding protein of the rho family YKR063C LAS1 involved in cell morphogenesis, cytoskeletal regulation and bud formation YKR082W NUP133 nuclear pore protein YKR101W SIR1 silencing regulatory protein YLL004W ORC3 origin recognition complex, 62 kDa subunit YLL021W SPA2 involved in cell polarity YLL039C UBI4 ubiquitin YLL050C COF1 cofilin, actin binding and severing protein YLR025W SNF7 class E Vps protein YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR175W CBF5 putative rRNA pseuduridine synthase YLR229C CDC42 GTP-binding protein of RAS superfamily YLR300W EXG1 exo-beta-1,3-glucanase (I/II), major isoform YLR307W CDA1 sporulation-specific chitin deacetylase YLR308W CDA2 sporulation-specific chitin deacetylase YLR313C SPH1 required for bipolar bud site selection YLR314C CDC3 cell division control protein YLR319C BUD6 bud site selection protein YLR330W CHS5 chitin synthesis protein YLR332W MID2 mating process protein YLR337C VRP1 verprolin YLR353W BUD8 budding protein YLR362W STE11 ser/thr protein kinase of the MEKK family YLR371W ROM2 GDP/GTP exchange factor for RHO1P YLR372W SUR4 sterol isomerase, fatty acid elongase YLR389C STE23 protease involved in a-factor processing YLR399C BDF1 sporulation protein YLR403W SFP1 zinc finger protein YLR433C CNA1 calcineurin B, catalytic subunit YLR441C RPS1A ribosomal protein S3a.e YLR442C SIR3 silencing regulatory and DNA-repair protein YLR452C SST2 involved in desensitization to alpha-factor pheromone YML032C RAD52 recombination and DNA repair protein YML057W CMP2 calcineurin B, catalytic subunit YML065W ORC1 origin recognition complex, 104 KD subunit YML109W ZDS2 multicopy suppressor of SIN4 YML115C VAN1 vanadate resistance protein YMR013C SEC59 dolichol kinase YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR017W SPO20 DBF2P interacting protein YMR022W QRI8 E2 ubiquitin-conjugation enzyme YMR043W MCM1 transcription factor of the MADS box family YMR052W FAR3 involved in pheromone-mediated cell cycle arrest YMR063W RIM9 regulator for sporulation and invasive growth YMR065W KAR5 nuclear fusion protein YMR100W MUB1 involved in budding YMR109W MYO5 myosin I YMR127C SAS2 involved in silencing at HMR YMR154C RIM13 calpain-like cysteine protease YMR165C SMP2 involved in plasmid maintenance, respiration and cell proliferation YMR190C SGS1 DNA helicase YMR232W FUS2 required for cell fusion during mating YMR238W DFG5 required for filamentous growth, cell polarity, and cellular elongation YMR263W SAP30 subunit of the histone deacetylase B complex YMR273C ZDS1 involved in negative regulation of cell polarity YNL012W SPO1 transcriptional regulator involved in sporulation YNL053W MSG5 dual-specifity protein phosphatase YNL066W SUN4 strong similarity to YIL123w, UTH1P, NCA3P and C. wickerhamii beta-glucosidase protein YNL079C TPM1 tropomyosin 1 YNL084C END3 required for endocytosis and cytoskeletal organization YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL098C RAS2 GTP-binding protein YNL138W SRV2 adenylate cyclase-associated protein, 70kDa YNL145W MFA2 mating pheromone a-factor 2 YNL154C YCK2 casein kinase I isoform YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YNL180C RHO5 similarity to S.pombe CDC42P and other GTP-binding proteins YNL188W KAR1 cell division control protein YNL192W CHS1 chitin synthase I YNL196C SLZ1 sporulation-specific protein YNL197C WHI3 involved in regulation of cell size YNL204C SPS18 sporulation-specific zinc-finger protein YNL225C CNM67 involved in cytokinesis YNL233W BNI4 bud neck involved YNL236W SIN4 global regulator protein YNL238W KEX2 endoproteinase of late golgi compartment YNL242W APG2 required for sporulation YNL243W SLA2 cytoskeleton assembly control protein YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL271C BNI1 regulator of budding YNL291C MID1 involved in Ca2+ influx during mating YNL307C MCK1 ser/thr/tyr protein kinase YNL320W YNL320W strong similarity to S.pombe Bem46 protein YNL327W EGT2 cell-cycle regulation protein YNL330C RPD3 histone deacetylase B YNR019W ARE2 acyl-CoA sterol acyltransferase YNR044W AGA1 a-agglutinin anchor subunit YNR052C POP2 required for glucose derepression YOL004W SIN3 transcription regulatory protein YOL025W LAG2 involved in determining longevity YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL052C SPE2 adenosylmethionine decarboxylase precursor YOL068C HST1 silencing protein YOL113W SKM1 STE20/PAK-like protein kinase YOL139C CDC33 translation initiation factor eIF4E YOR005C DNL4 DNA ligase IV YOR027W STI1 stress-induced protein YOR030W DFG16 involved in invasive growth upon nitrogen starvation YOR035C SHE4 required for mother cell-specific gene expression YOR043W WHI2 growth regulation protein YOR075W UFE1 syntaxin (T-SNARE) of the ER YOR101W RAS1 GTP-binding protein YOR122C PFY1 profilin YOR127W RGA1 RHO-type GTPase-activating protein for CDC42P YOR149C SMP3 protein kinase C pathway protein YOR156C NFI1 interacts with CDC12P in 2-hybrid assay YOR181W LAS17 component of actin cortical patches YOR188W MSB1 morphogenesis-related protein YOR190W SPR1 exo-1,3-beta-glucanase precursor YOR198C BFR1 maintenance of normal ploidy YOR208W PTP2 protein-tyrosine-phosphatase YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YOR219C STE13 type IV dipeptidyl aminopeptidase YOR231W MKK1 ser/thr protein kinase YOR281C PLP2 phosducin homologue, likely to be involved in regulation of pheromone response YOR290C SNF2 component of SWI/SNF global transcription activator complex YOR298W MUM3 required for meiosis YOR304C-A YOR304C-A similarity to mouse apolipoprotein A-IV precursor YOR313C SPS4 sporulation-specific protein YOR326W MYO2 myosin heavy chain YOR336W KRE5 killer toxin-resistance protein YOR361C PRT1 translation initiation factor eIF3 subunit YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL032C SVL3 strong similarity to PAM1P YPL046C ELC1 Elongin C transcription elongation factor YPL049C DIG1 MAP kinase-associated protein, down-regulator of invasive growth and mating YPL057C SUR1 required for mannosylation of sphingolipids YPL089C RLM1 transcription factor of the MADS box family YPL106C SSE1 heat shock protein of HSP70 family YPL115C BEM3 GTPase-activating protein for CDC42P and RHO1P YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL161C BEM4 bud emergence protein YPL187W MFALPHA1 mating pheromone alpha-1 precursor YPL240C HSP82 heat shock protein YPL242C IQG1 involved in cytokinesis, has similarity to mammalian IQGAP proteins YPL255W BBP1 cell division control protein YPL256C CLN2 cyclin, G1/S-specific YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YPR007C SPO69 protein required for meiosis and sporulation YPR032W SRO7 polarized exocytosis by regulating SNARE function YPR052C NHP6A nonhistone chromosomal protein related to mammalian HMG1 YPR054W SMK1 sporulation-specific MAP kinase YPR075C OPY2 pheromone resistant yeast 2 YPR103W PRE2 20S proteasome subunit (beta5) YPR119W CLB2 cyclin, G2/M-specific YPR122W AXL1 protease YPR141C KAR3 kinesin-related protein YPR159W KRE6 glucan synthase subunit YPR161C SGV1 ser/thr protein kinase YPR162C ORC4 origin recognition complex, 56 KD subunit YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins cell growth / morphogenesis (96 ORFs) 14.01 96 YAL016W TPD3 ser/thr protein phosphatase 2A, regulatory chain A YAL040C CLN3 cyclin, G1/S-specific YAL041W CDC24 GTP/GDP exchange factor for CDC42P YBL007C SLA1 cytoskeleton assembly control protein YBL105C PKC1 ser/thr protein kinase YBR015C MNN2 type II membrane protein YBR089C-A NHP6B nonhistone chromosomal protein YBR109C CMD1 calmodulin YBR160W CDC28 cyclin-dependent protein kinase YBR200W BEM1 bud emergence mediator YBR212W NGR1 glucose-repressible RNA-binding protein YBR234C ARC40 ARP2/3 protein complex subunit, 40 kilodalton YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR088W ABP1 actin-binding protein YDL006W PTC1 protein serine/threonine phosphatase 2c YDL029W ARP2 actin-like protein YDL035C GPR1 G-protein coupled receptor YDL134C PPH21 protein ser/thr phosphatase PP2A-1 YDL135C RDI1 rho GDP dissociation inhibitor with activity toward RHO1P YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL224C WHI4 strong similarity to WHI3 protein YDR075W PPH3 protein ser/thr phosphatase YDR099W BMH2 suppressor of clathrin deficiency YDR137W RGP1 reduced growth phenotype protein YDR151C CTH1 strong similarity to CCCH zinc finger protein TIS11P YDR182W CDC1 cell division control protein YDR251W PAM1 coiled-coil protein multicopy suppressor of loss of PP2A YDR261C EXG2 exo-beta-1,3-glucanase minor isoform YDR284C DPP1 diacylglycerol pyrophosphate phosphatase YDR293C SSD1 involved in the tolerance to high concentration of Ca2+ YDR299W BFR2 involved in protein transport steps at the Brefeldin A blocks YDR309C GIC2 CDC42 GTPase-binding protein YDR480W DIG2 MAP kinase-associated protein, down-regulator of invasive growth and mating YER020W GPA2 guanine nucleotide-binding regulatory protein YER072W VTC1 Negative Regulator of Cdc Fourty two (CDC42) YER170W ADK2 adenylate kinase, mitochondrial YER177W BMH1 14-3-3 protein involved in rapamycin-sensitive signalling YFL047W RGD2 GTPase activating protein YFR014C CMK1 Ca2+/calmodulin-dependent ser/thr protein kinase type I YGL095C VPS45 vacuolar protein sorting-associated protein YGL190C CDC55 ser/thr phosphatase 2A regulatory subunit B YGR070W ROM1 GDP/GTP exchange protein for RHO1P YGR167W CLC1 clathrin light chain YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR061C GIC1 CDC42 GTPase-binding protein YHR135C YCK1 casein kinase I isoform YHR205W SCH9 serine/threonine protein kinase involved in stress response and nutrient-sensing signaling pathway YHR206W SKN7 transcription factor with similarity to HSF1P YJL095W BCK1 ser/thr protein kinase of the MEKK family YJL174W KRE9 cell wall synthesis protein YJR032W CPR7 member of the cyclophilin family YJR075W HOC1 suppressor of PKC1 YJR090C GRR1 required for glucose repression and for glucose and cation transport YKL021C MAK11 involved in cell growth and replication of M1 dsRNA virus YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL185W ASH1 negative regulator of HO transcription YKL190W CNB1 calcineurin B, regulatory subunit YKL203C TOR2 phosphatidylinositol 3-kinase YLL021W SPA2 involved in cell polarity YLR175W CBF5 putative rRNA pseuduridine synthase YLR229C CDC42 GTP-binding protein of RAS superfamily YLR300W EXG1 exo-beta-1,3-glucanase (I/II), major isoform YLR337C VRP1 verprolin YLR371W ROM2 GDP/GTP exchange factor for RHO1P YLR403W SFP1 zinc finger protein YLR433C CNA1 calcineurin B, catalytic subunit YML057W CMP2 calcineurin B, catalytic subunit YMR165C SMP2 involved in plasmid maintenance, respiration and cell proliferation YMR263W SAP30 subunit of the histone deacetylase B complex YNL079C TPM1 tropomyosin 1 YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL138W SRV2 adenylate cyclase-associated protein, 70kDa YNL154C YCK2 casein kinase I isoform YNL180C RHO5 similarity to S.pombe CDC42P and other GTP-binding proteins YNL197C WHI3 involved in regulation of cell size YNL327W EGT2 cell-cycle regulation protein YOL052C SPE2 adenosylmethionine decarboxylase precursor YOL113W SKM1 STE20/PAK-like protein kinase YOR027W STI1 stress-induced protein YOR043W WHI2 growth regulation protein YOR075W UFE1 syntaxin (T-SNARE) of the ER YOR149C SMP3 protein kinase C pathway protein YOR231W MKK1 ser/thr protein kinase YOR336W KRE5 killer toxin-resistance protein YPL032C SVL3 strong similarity to PAM1P YPL089C RLM1 transcription factor of the MADS box family YPL106C SSE1 heat shock protein of HSP70 family YPL115C BEM3 GTPase-activating protein for CDC42P and RHO1P YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL161C BEM4 bud emergence protein YPL242C IQG1 involved in cytokinesis, has similarity to mammalian IQGAP proteins YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YPR052C NHP6A nonhistone chromosomal protein related to mammalian HMG1 YPR159W KRE6 glucan synthase subunit YPR161C SGV1 ser/thr protein kinase YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins directional cell growth (morphogenesis) (28 ORFs) 14.01.03 28 YAL041W CDC24 GTP/GDP exchange factor for CDC42P YBL105C PKC1 ser/thr protein kinase YBR109C CMD1 calmodulin YBR200W BEM1 bud emergence mediator YDL135C RDI1 rho GDP dissociation inhibitor with activity toward RHO1P YDR309C GIC2 CDC42 GTPase-binding protein YER072W VTC1 Negative Regulator of Cdc Fourty two (CDC42) YFL047W RGD2 GTPase activating protein YGL095C VPS45 vacuolar protein sorting-associated protein YGR070W ROM1 GDP/GTP exchange protein for RHO1P YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR061C GIC1 CDC42 GTPase-binding protein YJL095W BCK1 ser/thr protein kinase of the MEKK family YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL185W ASH1 negative regulator of HO transcription YLL021W SPA2 involved in cell polarity YLR229C CDC42 GTP-binding protein of RAS superfamily YLR371W ROM2 GDP/GTP exchange factor for RHO1P YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YOL113W SKM1 STE20/PAK-like protein kinase YOR149C SMP3 protein kinase C pathway protein YOR231W MKK1 ser/thr protein kinase YPL089C RLM1 transcription factor of the MADS box family YPL106C SSE1 heat shock protein of HSP70 family YPL115C BEM3 GTPase-activating protein for CDC42P and RHO1P YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL161C BEM4 bud emergence protein YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins other morphogenetic activities (12 ORFs) 14.01.03.99 12 YBR109C CMD1 calmodulin YBR200W BEM1 bud emergence mediator YDR309C GIC2 CDC42 GTPase-binding protein YER072W VTC1 Negative Regulator of Cdc Fourty two (CDC42) YGL095C VPS45 vacuolar protein sorting-associated protein YHR061C GIC1 CDC42 GTPase-binding protein YKL185W ASH1 negative regulator of HO transcription YLL021W SPA2 involved in cell polarity YOR149C SMP3 protein kinase C pathway protein YPL089C RLM1 transcription factor of the MADS box family YPL106C SSE1 heat shock protein of HSP70 family YPL161C BEM4 bud emergence protein cell differentiation (382 ORFs) 14.04 382 YAL009W SPO7 meiotic protein YAL016W TPD3 ser/thr protein phosphatase 2A, regulatory chain A YAL029C MYO4 myosin heavy chain, unconventional (class V) isoform YAL040C CLN3 cyclin, G1/S-specific YAL041W CDC24 GTP/GDP exchange factor for CDC42P YAR007C RFA1 DNA replication factor A, 69 KD subunit YBL015W ACH1 acetyl-CoA hydrolase YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBL028C YBL028C hypothetical protein - involved in mating-type regulation YBL052C SAS3 silencing protein YBL058W SHP1 potential regulatory subunit for GLC7P YBL066C SEF1 putative transcription factor YBL085W BOI1 BEM1 protein-binding protein YBL105C PKC1 ser/thr protein kinase YBL106C SRO77 polarized exocytosis by regulating SNARE function YBR023C CHS3 chitin synthase III YBR038W CHS2 chitin synthase II YBR040W FIG1 required for efficient mating YBR045C GIP1 GLC7-interacting protein YBR057C MUM2 meiotic protein YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR078W ECM33 involved in cell wall biogenesis and architecture YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR083W TEC1 Ty transcription activator YBR089C-A NHP6B nonhistone chromosomal protein YBR109C CMD1 calmodulin YBR130C SHE3 required for mother cell-specific expression of HO YBR148W YSW1 spore-specific protein YBR160W CDC28 cyclin-dependent protein kinase YBR161W YBR161W strong similarity to SUR1P YBR200W BEM1 bud emergence mediator YBR210W YBR210W strong similarity to D.melanogaster cornichon protein YBR234C ARC40 ARP2/3 protein complex subunit, 40 kilodalton YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR289W SNF5 component of SWI/SNF transcription activator complex YCL014W BUD3 budding protein YCL027W FUS1 cell fusion protein YCL029C BIK1 nuclear fusion protein YCL032W STE50 pheromone response pathway protein YCL048W YCL048W strong similarity to sporulation-specific protein SPS2P YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCL066W HMLALPHA1 mating type regulatory protein, silenced copy at HML YCL067C HMLALPHA2 mating type regulatory protein, silenced copy at HML YCR002C CDC10 cell division control protein YCR009C RVS161 similarity to human amphiphysin and RVS167P YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR038C BUD5 GDP/GTP exchange factor for RSR1P/Bud1p YCR039C MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040W MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCR048W ARE1 acyl-CoA sterol acyltransferase YCR057C PWP2 periodic tryptophan protein YCR086W CSM1 involved in nuclear migration YCR088W ABP1 actin-binding protein YCR089W FIG2 required for efficient mating YCR093W CDC39 nuclear protein YCR096C A2 mating type regulatory protein, silenced copy at HMR locus YCR097W A1 mating type regulatory protein, silenced copy at HMR locus YDL006W PTC1 protein serine/threonine phosphatase 2c YDL029W ARP2 actin-like protein YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL047W SIT4 ser/thr protein phosphatase YDL116W NUP84 nuclear pore protein YDL134C PPH21 protein ser/thr phosphatase PP2A-1 YDL135C RDI1 rho GDP dissociation inhibitor with activity toward RHO1P YDL159W STE7 ser/thr/tyr protein kinase of MAP kinase kinase family YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL225W SHS1 septin YDL227C HO homothallic switching endonuclease YDL240W LRG1 GTPase-activating protein of the rho/rac family YDR004W RAD57 DNA repair protein YDR055W PST1 strong similarity to SPS2 protein YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR069C DOA4 ubiquitin-specific protease YDR073W SNF11 component of SWI/SNF transcription activator complex YDR076W RAD55 DNA repair protein YDR085C AFR1 involved in morphogenesis of the mating projection YDR103W STE5 pheromone signal transduction pathway protein YDR104C SPO71 protein involved in spore wall formation YDR108W GSG1 sporulation specific protein YDR129C SAC6 actin filament bundling protein, fimbrin YDR143C SAN1 mating-type regulation protein YDR146C SWI5 transcription factor YDR173C ARG82 arginine metabolism transcription factor YDR177W UBC1 E2 ubiquitin-conjugating enzyme YDR182W CDC1 cell division control protein YDR191W HST4 member of the SIR2P family of putative NAD-dependent histone deacetylases YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR218C SPR28 septin-related sporulation protein YDR227W SIR4 silencing regulatory and DNA-repair protein YDR245W MNN10 subunit of mannosyltransferase complex YDR251W PAM1 coiled-coil protein multicopy suppressor of loss of PP2A YDR260C SWM1 developmentally regulated gene, is required for spore wall assembly YDR261C EXG2 exo-beta-1,3-glucanase minor isoform YDR264C AKR1 ankyrin repeat-containing protein YDR293C SSD1 involved in the tolerance to high concentration of Ca2+ YDR309C GIC2 CDC42 GTPase-binding protein YDR312W SSF2 protein with a potential role in mating YDR335W MSN5 multicopy supressor of SNF1 mutation YDR351W SBE2 bud growth protein YDR363W-A SEM1 regulator of exocytosis and pseudohyphal differentiation YDR388W RVS167 reduced viability upon starvation protein YDR392W SPT3 general transcriptional adaptor or co-activator YDR402C DIT2 cytochrome P450 56 YDR403W DIT1 spore wall maturation protein YDR461W MFA1 mating pheromone a-factor 1 YDR480W DIG2 MAP kinase-associated protein, down-regulator of invasive growth and mating YDR507C GIN4 ser/thr protein kinase YDR522C SPS2 sporulation-specific protein YDR523C SPS1 ser/thr protein kinase YER008C SEC3 component of exocyst complex YER012W PRE1 20S proteasome subunit C11(beta4) YER020W GPA2 guanine nucleotide-binding regulatory protein YER044C-A MEI4 meiosis-specific protein YER068W MOT2 transcriptional repressor YER075C PTP3 protein tyrosine phosphatase YER095W RAD51 DNA repair protein YER096W SHC1 sporulation specific protein YER100W UBC6 E2 ubiquitin-conjugating enzyme YER109C FLO8 required for diploid filamentous growth YER114C BOI2 budding protein YER115C SPR6 sporulation-specific protein YER125W RSP5 hect domain E3 ubiquitin-protein ligase YER132C PMD1 negative regulator of early meiotic expression YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER149C PEA2 involved in oriented growth toward mating partner YER155C BEM2 GTPase-activating protein YFL005W SEC4 GTP-binding protein of the ras superfamily YFL009W CDC4 cell division control protein YFL026W STE2 pheromone alpha-factor receptor YFL039C ACT1 actin YFR040W SAP155 SIT4P-associated protein YGL032C AGA2 a-agglutinin binding subunit YGL054C ERV14 ER-derived Vesicles YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL089C MF(ALPHA)2 mating pheromone alpha-2 factor YGL090W LIF1 DNA ligase IV interacting factor YGL095C VPS45 vacuolar protein sorting-associated protein YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL100W SEH1 nuclear pore protein YGL106W MLC1 MYO2P light chain YGL155W CDC43 geranylgeranyltransferase beta subunit YGL178W MPT5 multicopy suppressor of POP2 YGL180W APG1 essential for autophagocytosis YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL190C CDC55 ser/thr phosphatase 2A regulatory subunit B YGL192W IME4 positive transcription factor for IME2 YGL197W MDS3 negative regulator of early meiotic expression YGR009C SEC9 protein transport protein YGR014W MSB2 multicopy suppressor of a CDC24 bud emergence defect YGR023W MTL1 potential cell wall stres sensor YGR032W GSC2 1,3-beta-D-glucan synthase subunit YGR040W KSS1 ser/thr protein kinase of the MAP kinase family YGR041W BUD9 budding protein YGR059W SPR3 sporulation-specific septin YGR070W ROM1 GDP/GTP exchange protein for RHO1P YGR080W TWF1 twinfilin, an actin monomer sequestering protein YGR152C RSR1 GTP-binding protein YGR214W RPS0A 40S ribosomal protein p40 homolog A YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YGR217W CCH1 calcium channel protein YGR225W AMA1 required for sporulation YGR238C KEL2 involved in cell fusion and morphogenesis YGR253C PUP2 20S proteasome subunit(alpha5) YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHL024W RIM4 No sporulation YHL025W SNF6 global transcription activator YHR004C NEM1 required for nuclear morphology YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR023W MYO1 myosin-1 isoform (type II myosin) heavy chain YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR061C GIC1 CDC42 GTPase-binding protein YHR066W SSF1 mating protein YHR084W STE12 transcriptional activator YHR103W SBE22 golgi protein involved in yeast cell wall formation YHR107C CDC12 septin YHR118C ORC6 origin recognition complex, 50 KD subunit YHR119W SET1 involved in chromatin-mediated gene regulation YHR135C YCK1 casein kinase I isoform YHR139C SPS100 sporulation-specific wall maturation protein YHR146W CRP1 similarity to pheromone-response G-protein MDG1P YHR152W SPO12 sporulation protein YHR153C SPO16 sporulation protein YHR158C KEL1 involved in cell fusion and morphology YHR184W SSP1 essential for meiosis and spore formation YHR185C PFS1 similarity to S. pombe TEA1P YIL015W BAR1 barrierpepsin precursor YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL034C CAP2 F-actin capping protein, beta subunit YIL047C SYG1 member of the major facilitator superfamily YIL049W DFG10 involved in filamentous growth, cell polarity, and cellular elongation YIL073C SPO22 weak similarity to mouse polycystic kidney disease-related protein YIL084C SDS3 transcriptional regulator YIL099W SGA1 sporulation specific glucan 1,4-alpha-glucosidase YIL118W RHO3 GTP-binding protein of the rho family YIL124W AYR1 1-Acyldihydroxyacetone-phosphate reductase YIL138C TPM2 tropomyosin, isoform 2 YIL140W AXL2 required for axial pattern of budding YIL159W BNR1 regulator of budding YIR006C PAN1 actin-cytoskeleton assembly protein YIR026C YVH1 protein tyrosine phosphatase YJL001W PRE3 20S proteasome subunit (beta1) YJL005W CYR1 adenylate cyclase YJL078C PRY3 strong similarity to the plant PR-1 class of pathogen related proteins YJL079C PRY1 strong similarity to the plant PR-1 class of pathogen related proteins YJL095W BCK1 ser/thr protein kinase of the MEKK family YJL098W SAP185 SIT4P-associating protein YJL106W IME2 ser/thr protein kinase YJL146W IDS2 IME2-dependent signaling protein YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJL158C CIS3 strong similarity to PIR1P/HSP150P/PIR3P family YJL159W HSP150 member of the PIR1P/HSP150P/PIR3P family YJL160C YJL160C strong similarity to PIR1P/HSP150P/PIR3P family YJL170C ASG7 weak similarity to Helicobacter pylori endonuclease III YJL174W KRE9 cell wall synthesis protein YJL176C SWI3 transcription regulatory protein YJL212C OPT1 oligopeptide transporter specific for tetra- and pentapeptides YJR004C SAG1 alpha-agglutinin YJR042W NUP85 nuclear pore protein YJR075W HOC1 suppressor of PKC1 YJR076C CDC11 septin YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR092W BUD4 budding protein YJR094C IME1 transcription factor required for sporulation YJR117W STE24 zinc metallo-protease YKL007W CAP1 F-actin capping protein alpha subunit YKL043W PHD1 transcription factor YKL048C ELM1 ser/thr-specific protein kinase YKL079W SMY1 kinesin-related protein YKL092C BUD2 GTPase-activating protein for Bud1p/RSR1P YKL101W HSL1 ser/thr protein kinase, coupling septin ring assembly to cell cycle progression YKL104C GFA1 glucosamine--fructose-6-phosphate transaminase YKL117W SBA1 Hsp90 (Ninety) Associated Co-chaperone YKL129C MYO3 myosin type I YKL130C SHE2 required for mother cell-specific expression of HO YKL149C DBR1 lariat-debranching enzyme YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL165C MCD4 sporulation protein YKL178C STE3 pheromone a-factor receptor YKL181W PRS1 ribose-phosphate pyrophosphokinase YKL185W ASH1 negative regulator of HO transcription YKL189W HYM1 similarity to mouse hypothetical calcium-binding protein and D.melanogaster Mo25 gene YKL190W CNB1 calcineurin B, regulatory subunit YKL209C STE6 ATP-binding cassette transporter protein YKR028W SAP190 SIT4P-associated protein YKR031C SPO14 phospholipase D YKR048C NAP1 nucleosome assembly protein I YKR055W RHO4 GTP-binding protein of the rho family YKR063C LAS1 involved in cell morphogenesis, cytoskeletal regulation and bud formation YKR082W NUP133 nuclear pore protein YKR101W SIR1 silencing regulatory protein YLL004W ORC3 origin recognition complex, 62 kDa subunit YLL021W SPA2 involved in cell polarity YLL039C UBI4 ubiquitin YLL050C COF1 cofilin, actin binding and severing protein YLR025W SNF7 class E Vps protein YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR229C CDC42 GTP-binding protein of RAS superfamily YLR300W EXG1 exo-beta-1,3-glucanase (I/II), major isoform YLR307W CDA1 sporulation-specific chitin deacetylase YLR308W CDA2 sporulation-specific chitin deacetylase YLR313C SPH1 required for bipolar bud site selection YLR314C CDC3 cell division control protein YLR319C BUD6 bud site selection protein YLR330W CHS5 chitin synthesis protein YLR332W MID2 mating process protein YLR337C VRP1 verprolin YLR353W BUD8 budding protein YLR362W STE11 ser/thr protein kinase of the MEKK family YLR371W ROM2 GDP/GTP exchange factor for RHO1P YLR372W SUR4 sterol isomerase, fatty acid elongase YLR389C STE23 protease involved in a-factor processing YLR399C BDF1 sporulation protein YLR433C CNA1 calcineurin B, catalytic subunit YLR441C RPS1A ribosomal protein S3a.e YLR442C SIR3 silencing regulatory and DNA-repair protein YLR452C SST2 involved in desensitization to alpha-factor pheromone YML032C RAD52 recombination and DNA repair protein YML057W CMP2 calcineurin B, catalytic subunit YML065W ORC1 origin recognition complex, 104 KD subunit YML109W ZDS2 multicopy suppressor of SIN4 YML115C VAN1 vanadate resistance protein YMR013C SEC59 dolichol kinase YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR017W SPO20 DBF2P interacting protein YMR022W QRI8 E2 ubiquitin-conjugation enzyme YMR043W MCM1 transcription factor of the MADS box family YMR052W FAR3 involved in pheromone-mediated cell cycle arrest YMR063W RIM9 regulator for sporulation and invasive growth YMR065W KAR5 nuclear fusion protein YMR100W MUB1 involved in budding YMR109W MYO5 myosin I YMR127C SAS2 involved in silencing at HMR YMR154C RIM13 calpain-like cysteine protease YMR232W FUS2 required for cell fusion during mating YMR238W DFG5 required for filamentous growth, cell polarity, and cellular elongation YMR263W SAP30 subunit of the histone deacetylase B complex YMR273C ZDS1 involved in negative regulation of cell polarity YNL012W SPO1 transcriptional regulator involved in sporulation YNL053W MSG5 dual-specifity protein phosphatase YNL079C TPM1 tropomyosin 1 YNL084C END3 required for endocytosis and cytoskeletal organization YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL098C RAS2 GTP-binding protein YNL138W SRV2 adenylate cyclase-associated protein, 70kDa YNL145W MFA2 mating pheromone a-factor 2 YNL154C YCK2 casein kinase I isoform YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YNL188W KAR1 cell division control protein YNL192W CHS1 chitin synthase I YNL196C SLZ1 sporulation-specific protein YNL197C WHI3 involved in regulation of cell size YNL204C SPS18 sporulation-specific zinc-finger protein YNL225C CNM67 involved in cytokinesis YNL233W BNI4 bud neck involved YNL236W SIN4 global regulator protein YNL238W KEX2 endoproteinase of late golgi compartment YNL242W APG2 required for sporulation YNL243W SLA2 cytoskeleton assembly control protein YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL271C BNI1 regulator of budding YNL291C MID1 involved in Ca2+ influx during mating YNL307C MCK1 ser/thr/tyr protein kinase YNL320W YNL320W strong similarity to S.pombe Bem46 protein YNL330C RPD3 histone deacetylase B YNR019W ARE2 acyl-CoA sterol acyltransferase YNR044W AGA1 a-agglutinin anchor subunit YNR052C POP2 required for glucose derepression YOL004W SIN3 transcription regulatory protein YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL052C SPE2 adenosylmethionine decarboxylase precursor YOL068C HST1 silencing protein YOL139C CDC33 translation initiation factor eIF4E YOR005C DNL4 DNA ligase IV YOR030W DFG16 involved in invasive growth upon nitrogen starvation YOR035C SHE4 required for mother cell-specific gene expression YOR075W UFE1 syntaxin (T-SNARE) of the ER YOR122C PFY1 profilin YOR127W RGA1 RHO-type GTPase-activating protein for CDC42P YOR149C SMP3 protein kinase C pathway protein YOR156C NFI1 interacts with CDC12P in 2-hybrid assay YOR181W LAS17 component of actin cortical patches YOR188W MSB1 morphogenesis-related protein YOR190W SPR1 exo-1,3-beta-glucanase precursor YOR198C BFR1 maintenance of normal ploidy YOR208W PTP2 protein-tyrosine-phosphatase YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YOR219C STE13 type IV dipeptidyl aminopeptidase YOR231W MKK1 ser/thr protein kinase YOR281C PLP2 phosducin homologue, likely to be involved in regulation of pheromone response YOR290C SNF2 component of SWI/SNF global transcription activator complex YOR298W MUM3 required for meiosis YOR304C-A YOR304C-A similarity to mouse apolipoprotein A-IV precursor YOR313C SPS4 sporulation-specific protein YOR326W MYO2 myosin heavy chain YOR361C PRT1 translation initiation factor eIF3 subunit YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL032C SVL3 strong similarity to PAM1P YPL046C ELC1 Elongin C transcription elongation factor YPL049C DIG1 MAP kinase-associated protein, down-regulator of invasive growth and mating YPL057C SUR1 required for mannosylation of sphingolipids YPL115C BEM3 GTPase-activating protein for CDC42P and RHO1P YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL161C BEM4 bud emergence protein YPL187W MFALPHA1 mating pheromone alpha-1 precursor YPL240C HSP82 heat shock protein YPL242C IQG1 involved in cytokinesis, has similarity to mammalian IQGAP proteins YPL255W BBP1 cell division control protein YPL256C CLN2 cyclin, G1/S-specific YPR007C SPO69 protein required for meiosis and sporulation YPR032W SRO7 polarized exocytosis by regulating SNARE function YPR052C NHP6A nonhistone chromosomal protein related to mammalian HMG1 YPR054W SMK1 sporulation-specific MAP kinase YPR075C OPY2 pheromone resistant yeast 2 YPR103W PRE2 20S proteasome subunit (beta5) YPR119W CLB2 cyclin, G2/M-specific YPR122W AXL1 protease YPR141C KAR3 kinesin-related protein YPR161C SGV1 ser/thr protein kinase YPR162C ORC4 origin recognition complex, 56 KD subunit YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins fungal cell differentiation (382 ORFs) 14.04.03 382 YAL009W SPO7 meiotic protein YAL016W TPD3 ser/thr protein phosphatase 2A, regulatory chain A YAL029C MYO4 myosin heavy chain, unconventional (class V) isoform YAL040C CLN3 cyclin, G1/S-specific YAL041W CDC24 GTP/GDP exchange factor for CDC42P YAR007C RFA1 DNA replication factor A, 69 KD subunit YBL015W ACH1 acetyl-CoA hydrolase YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBL028C YBL028C hypothetical protein - involved in mating-type regulation YBL052C SAS3 silencing protein YBL058W SHP1 potential regulatory subunit for GLC7P YBL066C SEF1 putative transcription factor YBL085W BOI1 BEM1 protein-binding protein YBL105C PKC1 ser/thr protein kinase YBL106C SRO77 polarized exocytosis by regulating SNARE function YBR023C CHS3 chitin synthase III YBR038W CHS2 chitin synthase II YBR040W FIG1 required for efficient mating YBR045C GIP1 GLC7-interacting protein YBR057C MUM2 meiotic protein YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR078W ECM33 involved in cell wall biogenesis and architecture YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR083W TEC1 Ty transcription activator YBR089C-A NHP6B nonhistone chromosomal protein YBR109C CMD1 calmodulin YBR130C SHE3 required for mother cell-specific expression of HO YBR148W YSW1 spore-specific protein YBR160W CDC28 cyclin-dependent protein kinase YBR161W YBR161W strong similarity to SUR1P YBR200W BEM1 bud emergence mediator YBR210W YBR210W strong similarity to D.melanogaster cornichon protein YBR234C ARC40 ARP2/3 protein complex subunit, 40 kilodalton YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR289W SNF5 component of SWI/SNF transcription activator complex YCL014W BUD3 budding protein YCL027W FUS1 cell fusion protein YCL029C BIK1 nuclear fusion protein YCL032W STE50 pheromone response pathway protein YCL048W YCL048W strong similarity to sporulation-specific protein SPS2P YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCL066W HMLALPHA1 mating type regulatory protein, silenced copy at HML YCL067C HMLALPHA2 mating type regulatory protein, silenced copy at HML YCR002C CDC10 cell division control protein YCR009C RVS161 similarity to human amphiphysin and RVS167P YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR038C BUD5 GDP/GTP exchange factor for RSR1P/Bud1p YCR039C MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040W MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCR048W ARE1 acyl-CoA sterol acyltransferase YCR057C PWP2 periodic tryptophan protein YCR086W CSM1 involved in nuclear migration YCR088W ABP1 actin-binding protein YCR089W FIG2 required for efficient mating YCR093W CDC39 nuclear protein YCR096C A2 mating type regulatory protein, silenced copy at HMR locus YCR097W A1 mating type regulatory protein, silenced copy at HMR locus YDL006W PTC1 protein serine/threonine phosphatase 2c YDL029W ARP2 actin-like protein YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL047W SIT4 ser/thr protein phosphatase YDL116W NUP84 nuclear pore protein YDL134C PPH21 protein ser/thr phosphatase PP2A-1 YDL135C RDI1 rho GDP dissociation inhibitor with activity toward RHO1P YDL159W STE7 ser/thr/tyr protein kinase of MAP kinase kinase family YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL225W SHS1 septin YDL227C HO homothallic switching endonuclease YDL240W LRG1 GTPase-activating protein of the rho/rac family YDR004W RAD57 DNA repair protein YDR055W PST1 strong similarity to SPS2 protein YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR069C DOA4 ubiquitin-specific protease YDR073W SNF11 component of SWI/SNF transcription activator complex YDR076W RAD55 DNA repair protein YDR085C AFR1 involved in morphogenesis of the mating projection YDR103W STE5 pheromone signal transduction pathway protein YDR104C SPO71 protein involved in spore wall formation YDR108W GSG1 sporulation specific protein YDR129C SAC6 actin filament bundling protein, fimbrin YDR143C SAN1 mating-type regulation protein YDR146C SWI5 transcription factor YDR173C ARG82 arginine metabolism transcription factor YDR177W UBC1 E2 ubiquitin-conjugating enzyme YDR182W CDC1 cell division control protein YDR191W HST4 member of the SIR2P family of putative NAD-dependent histone deacetylases YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR218C SPR28 septin-related sporulation protein YDR227W SIR4 silencing regulatory and DNA-repair protein YDR245W MNN10 subunit of mannosyltransferase complex YDR251W PAM1 coiled-coil protein multicopy suppressor of loss of PP2A YDR260C SWM1 developmentally regulated gene, is required for spore wall assembly YDR261C EXG2 exo-beta-1,3-glucanase minor isoform YDR264C AKR1 ankyrin repeat-containing protein YDR293C SSD1 involved in the tolerance to high concentration of Ca2+ YDR309C GIC2 CDC42 GTPase-binding protein YDR312W SSF2 protein with a potential role in mating YDR335W MSN5 multicopy supressor of SNF1 mutation YDR351W SBE2 bud growth protein YDR363W-A SEM1 regulator of exocytosis and pseudohyphal differentiation YDR388W RVS167 reduced viability upon starvation protein YDR392W SPT3 general transcriptional adaptor or co-activator YDR402C DIT2 cytochrome P450 56 YDR403W DIT1 spore wall maturation protein YDR461W MFA1 mating pheromone a-factor 1 YDR480W DIG2 MAP kinase-associated protein, down-regulator of invasive growth and mating YDR507C GIN4 ser/thr protein kinase YDR522C SPS2 sporulation-specific protein YDR523C SPS1 ser/thr protein kinase YER008C SEC3 component of exocyst complex YER012W PRE1 20S proteasome subunit C11(beta4) YER020W GPA2 guanine nucleotide-binding regulatory protein YER044C-A MEI4 meiosis-specific protein YER068W MOT2 transcriptional repressor YER075C PTP3 protein tyrosine phosphatase YER095W RAD51 DNA repair protein YER096W SHC1 sporulation specific protein YER100W UBC6 E2 ubiquitin-conjugating enzyme YER109C FLO8 required for diploid filamentous growth YER114C BOI2 budding protein YER115C SPR6 sporulation-specific protein YER125W RSP5 hect domain E3 ubiquitin-protein ligase YER132C PMD1 negative regulator of early meiotic expression YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER149C PEA2 involved in oriented growth toward mating partner YER155C BEM2 GTPase-activating protein YFL005W SEC4 GTP-binding protein of the ras superfamily YFL009W CDC4 cell division control protein YFL026W STE2 pheromone alpha-factor receptor YFL039C ACT1 actin YFR040W SAP155 SIT4P-associated protein YGL032C AGA2 a-agglutinin binding subunit YGL054C ERV14 ER-derived Vesicles YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL089C MF(ALPHA)2 mating pheromone alpha-2 factor YGL090W LIF1 DNA ligase IV interacting factor YGL095C VPS45 vacuolar protein sorting-associated protein YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL100W SEH1 nuclear pore protein YGL106W MLC1 MYO2P light chain YGL155W CDC43 geranylgeranyltransferase beta subunit YGL178W MPT5 multicopy suppressor of POP2 YGL180W APG1 essential for autophagocytosis YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL190C CDC55 ser/thr phosphatase 2A regulatory subunit B YGL192W IME4 positive transcription factor for IME2 YGL197W MDS3 negative regulator of early meiotic expression YGR009C SEC9 protein transport protein YGR014W MSB2 multicopy suppressor of a CDC24 bud emergence defect YGR023W MTL1 potential cell wall stres sensor YGR032W GSC2 1,3-beta-D-glucan synthase subunit YGR040W KSS1 ser/thr protein kinase of the MAP kinase family YGR041W BUD9 budding protein YGR059W SPR3 sporulation-specific septin YGR070W ROM1 GDP/GTP exchange protein for RHO1P YGR080W TWF1 twinfilin, an actin monomer sequestering protein YGR152C RSR1 GTP-binding protein YGR214W RPS0A 40S ribosomal protein p40 homolog A YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YGR217W CCH1 calcium channel protein YGR225W AMA1 required for sporulation YGR238C KEL2 involved in cell fusion and morphogenesis YGR253C PUP2 20S proteasome subunit(alpha5) YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHL024W RIM4 No sporulation YHL025W SNF6 global transcription activator YHR004C NEM1 required for nuclear morphology YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR023W MYO1 myosin-1 isoform (type II myosin) heavy chain YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR061C GIC1 CDC42 GTPase-binding protein YHR066W SSF1 mating protein YHR084W STE12 transcriptional activator YHR103W SBE22 golgi protein involved in yeast cell wall formation YHR107C CDC12 septin YHR118C ORC6 origin recognition complex, 50 KD subunit YHR119W SET1 involved in chromatin-mediated gene regulation YHR135C YCK1 casein kinase I isoform YHR139C SPS100 sporulation-specific wall maturation protein YHR146W CRP1 similarity to pheromone-response G-protein MDG1P YHR152W SPO12 sporulation protein YHR153C SPO16 sporulation protein YHR158C KEL1 involved in cell fusion and morphology YHR184W SSP1 essential for meiosis and spore formation YHR185C PFS1 similarity to S. pombe TEA1P YIL015W BAR1 barrierpepsin precursor YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL034C CAP2 F-actin capping protein, beta subunit YIL047C SYG1 member of the major facilitator superfamily YIL049W DFG10 involved in filamentous growth, cell polarity, and cellular elongation YIL073C SPO22 weak similarity to mouse polycystic kidney disease-related protein YIL084C SDS3 transcriptional regulator YIL099W SGA1 sporulation specific glucan 1,4-alpha-glucosidase YIL118W RHO3 GTP-binding protein of the rho family YIL124W AYR1 1-Acyldihydroxyacetone-phosphate reductase YIL138C TPM2 tropomyosin, isoform 2 YIL140W AXL2 required for axial pattern of budding YIL159W BNR1 regulator of budding YIR006C PAN1 actin-cytoskeleton assembly protein YIR026C YVH1 protein tyrosine phosphatase YJL001W PRE3 20S proteasome subunit (beta1) YJL005W CYR1 adenylate cyclase YJL078C PRY3 strong similarity to the plant PR-1 class of pathogen related proteins YJL079C PRY1 strong similarity to the plant PR-1 class of pathogen related proteins YJL095W BCK1 ser/thr protein kinase of the MEKK family YJL098W SAP185 SIT4P-associating protein YJL106W IME2 ser/thr protein kinase YJL146W IDS2 IME2-dependent signaling protein YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJL158C CIS3 strong similarity to PIR1P/HSP150P/PIR3P family YJL159W HSP150 member of the PIR1P/HSP150P/PIR3P family YJL160C YJL160C strong similarity to PIR1P/HSP150P/PIR3P family YJL170C ASG7 weak similarity to Helicobacter pylori endonuclease III YJL174W KRE9 cell wall synthesis protein YJL176C SWI3 transcription regulatory protein YJL212C OPT1 oligopeptide transporter specific for tetra- and pentapeptides YJR004C SAG1 alpha-agglutinin YJR042W NUP85 nuclear pore protein YJR075W HOC1 suppressor of PKC1 YJR076C CDC11 septin YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR092W BUD4 budding protein YJR094C IME1 transcription factor required for sporulation YJR117W STE24 zinc metallo-protease YKL007W CAP1 F-actin capping protein alpha subunit YKL043W PHD1 transcription factor YKL048C ELM1 ser/thr-specific protein kinase YKL079W SMY1 kinesin-related protein YKL092C BUD2 GTPase-activating protein for Bud1p/RSR1P YKL101W HSL1 ser/thr protein kinase, coupling septin ring assembly to cell cycle progression YKL104C GFA1 glucosamine--fructose-6-phosphate transaminase YKL117W SBA1 Hsp90 (Ninety) Associated Co-chaperone YKL129C MYO3 myosin type I YKL130C SHE2 required for mother cell-specific expression of HO YKL149C DBR1 lariat-debranching enzyme YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL165C MCD4 sporulation protein YKL178C STE3 pheromone a-factor receptor YKL181W PRS1 ribose-phosphate pyrophosphokinase YKL185W ASH1 negative regulator of HO transcription YKL189W HYM1 similarity to mouse hypothetical calcium-binding protein and D.melanogaster Mo25 gene YKL190W CNB1 calcineurin B, regulatory subunit YKL209C STE6 ATP-binding cassette transporter protein YKR028W SAP190 SIT4P-associated protein YKR031C SPO14 phospholipase D YKR048C NAP1 nucleosome assembly protein I YKR055W RHO4 GTP-binding protein of the rho family YKR063C LAS1 involved in cell morphogenesis, cytoskeletal regulation and bud formation YKR082W NUP133 nuclear pore protein YKR101W SIR1 silencing regulatory protein YLL004W ORC3 origin recognition complex, 62 kDa subunit YLL021W SPA2 involved in cell polarity YLL039C UBI4 ubiquitin YLL050C COF1 cofilin, actin binding and severing protein YLR025W SNF7 class E Vps protein YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR229C CDC42 GTP-binding protein of RAS superfamily YLR300W EXG1 exo-beta-1,3-glucanase (I/II), major isoform YLR307W CDA1 sporulation-specific chitin deacetylase YLR308W CDA2 sporulation-specific chitin deacetylase YLR313C SPH1 required for bipolar bud site selection YLR314C CDC3 cell division control protein YLR319C BUD6 bud site selection protein YLR330W CHS5 chitin synthesis protein YLR332W MID2 mating process protein YLR337C VRP1 verprolin YLR353W BUD8 budding protein YLR362W STE11 ser/thr protein kinase of the MEKK family YLR371W ROM2 GDP/GTP exchange factor for RHO1P YLR372W SUR4 sterol isomerase, fatty acid elongase YLR389C STE23 protease involved in a-factor processing YLR399C BDF1 sporulation protein YLR433C CNA1 calcineurin B, catalytic subunit YLR441C RPS1A ribosomal protein S3a.e YLR442C SIR3 silencing regulatory and DNA-repair protein YLR452C SST2 involved in desensitization to alpha-factor pheromone YML032C RAD52 recombination and DNA repair protein YML057W CMP2 calcineurin B, catalytic subunit YML065W ORC1 origin recognition complex, 104 KD subunit YML109W ZDS2 multicopy suppressor of SIN4 YML115C VAN1 vanadate resistance protein YMR013C SEC59 dolichol kinase YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR017W SPO20 DBF2P interacting protein YMR022W QRI8 E2 ubiquitin-conjugation enzyme YMR043W MCM1 transcription factor of the MADS box family YMR052W FAR3 involved in pheromone-mediated cell cycle arrest YMR063W RIM9 regulator for sporulation and invasive growth YMR065W KAR5 nuclear fusion protein YMR100W MUB1 involved in budding YMR109W MYO5 myosin I YMR127C SAS2 involved in silencing at HMR YMR154C RIM13 calpain-like cysteine protease YMR232W FUS2 required for cell fusion during mating YMR238W DFG5 required for filamentous growth, cell polarity, and cellular elongation YMR263W SAP30 subunit of the histone deacetylase B complex YMR273C ZDS1 involved in negative regulation of cell polarity YNL012W SPO1 transcriptional regulator involved in sporulation YNL053W MSG5 dual-specifity protein phosphatase YNL079C TPM1 tropomyosin 1 YNL084C END3 required for endocytosis and cytoskeletal organization YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL098C RAS2 GTP-binding protein YNL138W SRV2 adenylate cyclase-associated protein, 70kDa YNL145W MFA2 mating pheromone a-factor 2 YNL154C YCK2 casein kinase I isoform YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YNL188W KAR1 cell division control protein YNL192W CHS1 chitin synthase I YNL196C SLZ1 sporulation-specific protein YNL197C WHI3 involved in regulation of cell size YNL204C SPS18 sporulation-specific zinc-finger protein YNL225C CNM67 involved in cytokinesis YNL233W BNI4 bud neck involved YNL236W SIN4 global regulator protein YNL238W KEX2 endoproteinase of late golgi compartment YNL242W APG2 required for sporulation YNL243W SLA2 cytoskeleton assembly control protein YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL271C BNI1 regulator of budding YNL291C MID1 involved in Ca2+ influx during mating YNL307C MCK1 ser/thr/tyr protein kinase YNL320W YNL320W strong similarity to S.pombe Bem46 protein YNL330C RPD3 histone deacetylase B YNR019W ARE2 acyl-CoA sterol acyltransferase YNR044W AGA1 a-agglutinin anchor subunit YNR052C POP2 required for glucose derepression YOL004W SIN3 transcription regulatory protein YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL052C SPE2 adenosylmethionine decarboxylase precursor YOL068C HST1 silencing protein YOL139C CDC33 translation initiation factor eIF4E YOR005C DNL4 DNA ligase IV YOR030W DFG16 involved in invasive growth upon nitrogen starvation YOR035C SHE4 required for mother cell-specific gene expression YOR075W UFE1 syntaxin (T-SNARE) of the ER YOR122C PFY1 profilin YOR127W RGA1 RHO-type GTPase-activating protein for CDC42P YOR149C SMP3 protein kinase C pathway protein YOR156C NFI1 interacts with CDC12P in 2-hybrid assay YOR181W LAS17 component of actin cortical patches YOR188W MSB1 morphogenesis-related protein YOR190W SPR1 exo-1,3-beta-glucanase precursor YOR198C BFR1 maintenance of normal ploidy YOR208W PTP2 protein-tyrosine-phosphatase YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YOR219C STE13 type IV dipeptidyl aminopeptidase YOR231W MKK1 ser/thr protein kinase YOR281C PLP2 phosducin homologue, likely to be involved in regulation of pheromone response YOR290C SNF2 component of SWI/SNF global transcription activator complex YOR298W MUM3 required for meiosis YOR304C-A YOR304C-A similarity to mouse apolipoprotein A-IV precursor YOR313C SPS4 sporulation-specific protein YOR326W MYO2 myosin heavy chain YOR361C PRT1 translation initiation factor eIF3 subunit YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL032C SVL3 strong similarity to PAM1P YPL046C ELC1 Elongin C transcription elongation factor YPL049C DIG1 MAP kinase-associated protein, down-regulator of invasive growth and mating YPL057C SUR1 required for mannosylation of sphingolipids YPL115C BEM3 GTPase-activating protein for CDC42P and RHO1P YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL161C BEM4 bud emergence protein YPL187W MFALPHA1 mating pheromone alpha-1 precursor YPL240C HSP82 heat shock protein YPL242C IQG1 involved in cytokinesis, has similarity to mammalian IQGAP proteins YPL255W BBP1 cell division control protein YPL256C CLN2 cyclin, G1/S-specific YPR007C SPO69 protein required for meiosis and sporulation YPR032W SRO7 polarized exocytosis by regulating SNARE function YPR052C NHP6A nonhistone chromosomal protein related to mammalian HMG1 YPR054W SMK1 sporulation-specific MAP kinase YPR075C OPY2 pheromone resistant yeast 2 YPR103W PRE2 20S proteasome subunit (beta5) YPR119W CLB2 cyclin, G2/M-specific YPR122W AXL1 protease YPR141C KAR3 kinesin-related protein YPR161C SGV1 ser/thr protein kinase YPR162C ORC4 origin recognition complex, 56 KD subunit YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins budding, cell polarity and filament formation (170 ORFs) 14.04.03.01 170 YAL016W TPD3 ser/thr protein phosphatase 2A, regulatory chain A YAL029C MYO4 myosin heavy chain, unconventional (class V) isoform YAL040C CLN3 cyclin, G1/S-specific YAL041W CDC24 GTP/GDP exchange factor for CDC42P YBL058W SHP1 potential regulatory subunit for GLC7P YBL085W BOI1 BEM1 protein-binding protein YBL105C PKC1 ser/thr protein kinase YBL106C SRO77 polarized exocytosis by regulating SNARE function YBR023C CHS3 chitin synthase III YBR038W CHS2 chitin synthase II YBR083W TEC1 Ty transcription activator YBR089C-A NHP6B nonhistone chromosomal protein YBR109C CMD1 calmodulin YBR160W CDC28 cyclin-dependent protein kinase YBR161W YBR161W strong similarity to SUR1P YBR200W BEM1 bud emergence mediator YBR210W YBR210W strong similarity to D.melanogaster cornichon protein YBR234C ARC40 ARP2/3 protein complex subunit, 40 kilodalton YCL014W BUD3 budding protein YCR009C RVS161 similarity to human amphiphysin and RVS167P YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR038C BUD5 GDP/GTP exchange factor for RSR1P/Bud1p YCR057C PWP2 periodic tryptophan protein YCR088W ABP1 actin-binding protein YCR093W CDC39 nuclear protein YDL006W PTC1 protein serine/threonine phosphatase 2c YDL029W ARP2 actin-like protein YDL047W SIT4 ser/thr protein phosphatase YDL134C PPH21 protein ser/thr phosphatase PP2A-1 YDL135C RDI1 rho GDP dissociation inhibitor with activity toward RHO1P YDL159W STE7 ser/thr/tyr protein kinase of MAP kinase kinase family YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL225W SHS1 septin YDR085C AFR1 involved in morphogenesis of the mating projection YDR129C SAC6 actin filament bundling protein, fimbrin YDR182W CDC1 cell division control protein YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR245W MNN10 subunit of mannosyltransferase complex YDR251W PAM1 coiled-coil protein multicopy suppressor of loss of PP2A YDR260C SWM1 developmentally regulated gene, is required for spore wall assembly YDR293C SSD1 involved in the tolerance to high concentration of Ca2+ YDR309C GIC2 CDC42 GTPase-binding protein YDR351W SBE2 bud growth protein YDR363W-A SEM1 regulator of exocytosis and pseudohyphal differentiation YDR388W RVS167 reduced viability upon starvation protein YDR507C GIN4 ser/thr protein kinase YER008C SEC3 component of exocyst complex YER020W GPA2 guanine nucleotide-binding regulatory protein YER109C FLO8 required for diploid filamentous growth YER114C BOI2 budding protein YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER149C PEA2 involved in oriented growth toward mating partner YER155C BEM2 GTPase-activating protein YFL005W SEC4 GTP-binding protein of the ras superfamily YFL009W CDC4 cell division control protein YFL039C ACT1 actin YFR040W SAP155 SIT4P-associated protein YGL054C ERV14 ER-derived Vesicles YGL095C VPS45 vacuolar protein sorting-associated protein YGL106W MLC1 MYO2P light chain YGL155W CDC43 geranylgeranyltransferase beta subunit YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL190C CDC55 ser/thr phosphatase 2A regulatory subunit B YGR009C SEC9 protein transport protein YGR014W MSB2 multicopy suppressor of a CDC24 bud emergence defect YGR041W BUD9 budding protein YGR070W ROM1 GDP/GTP exchange protein for RHO1P YGR080W TWF1 twinfilin, an actin monomer sequestering protein YGR152C RSR1 GTP-binding protein YGR214W RPS0A 40S ribosomal protein p40 homolog A YGR238C KEL2 involved in cell fusion and morphogenesis YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHR023W MYO1 myosin-1 isoform (type II myosin) heavy chain YHR030C SLT2 ser/thr protein kinase of MAP kinase family YHR061C GIC1 CDC42 GTPase-binding protein YHR084W STE12 transcriptional activator YHR103W SBE22 golgi protein involved in yeast cell wall formation YHR107C CDC12 septin YHR135C YCK1 casein kinase I isoform YHR158C KEL1 involved in cell fusion and morphology YIL034C CAP2 F-actin capping protein, beta subunit YIL049W DFG10 involved in filamentous growth, cell polarity, and cellular elongation YIL118W RHO3 GTP-binding protein of the rho family YIL138C TPM2 tropomyosin, isoform 2 YIL140W AXL2 required for axial pattern of budding YIL159W BNR1 regulator of budding YIR006C PAN1 actin-cytoskeleton assembly protein YJL095W BCK1 ser/thr protein kinase of the MEKK family YJL098W SAP185 SIT4P-associating protein YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJL158C CIS3 strong similarity to PIR1P/HSP150P/PIR3P family YJL159W HSP150 member of the PIR1P/HSP150P/PIR3P family YJL160C YJL160C strong similarity to PIR1P/HSP150P/PIR3P family YJL174W KRE9 cell wall synthesis protein YJR075W HOC1 suppressor of PKC1 YJR076C CDC11 septin YJR090C GRR1 required for glucose repression and for glucose and cation transport YJR092W BUD4 budding protein YKL007W CAP1 F-actin capping protein alpha subunit YKL043W PHD1 transcription factor YKL048C ELM1 ser/thr-specific protein kinase YKL079W SMY1 kinesin-related protein YKL092C BUD2 GTPase-activating protein for Bud1p/RSR1P YKL101W HSL1 ser/thr protein kinase, coupling septin ring assembly to cell cycle progression YKL129C MYO3 myosin type I YKL149C DBR1 lariat-debranching enzyme YKL161C (MLP1) strong similarity to ser/thr-specific protein kinase SLT2P YKL181W PRS1 ribose-phosphate pyrophosphokinase YKL185W ASH1 negative regulator of HO transcription YKL189W HYM1 similarity to mouse hypothetical calcium-binding protein and D.melanogaster Mo25 gene YKR028W SAP190 SIT4P-associated protein YKR048C NAP1 nucleosome assembly protein I YKR055W RHO4 GTP-binding protein of the rho family YKR063C LAS1 involved in cell morphogenesis, cytoskeletal regulation and bud formation YLL021W SPA2 involved in cell polarity YLL050C COF1 cofilin, actin binding and severing protein YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR229C CDC42 GTP-binding protein of RAS superfamily YLR313C SPH1 required for bipolar bud site selection YLR314C CDC3 cell division control protein YLR319C BUD6 bud site selection protein YLR330W CHS5 chitin synthesis protein YLR337C VRP1 verprolin YLR353W BUD8 budding protein YLR362W STE11 ser/thr protein kinase of the MEKK family YLR371W ROM2 GDP/GTP exchange factor for RHO1P YLR372W SUR4 sterol isomerase, fatty acid elongase YML109W ZDS2 multicopy suppressor of SIN4 YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR063W RIM9 regulator for sporulation and invasive growth YMR100W MUB1 involved in budding YMR109W MYO5 myosin I YMR238W DFG5 required for filamentous growth, cell polarity, and cellular elongation YMR273C ZDS1 involved in negative regulation of cell polarity YNL079C TPM1 tropomyosin 1 YNL084C END3 required for endocytosis and cytoskeletal organization YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL138W SRV2 adenylate cyclase-associated protein, 70kDa YNL154C YCK2 casein kinase I isoform YNL197C WHI3 involved in regulation of cell size YNL233W BNI4 bud neck involved YNL243W SLA2 cytoskeleton assembly control protein YNL271C BNI1 regulator of budding YNL320W YNL320W strong similarity to S.pombe Bem46 protein YOR030W DFG16 involved in invasive growth upon nitrogen starvation YOR122C PFY1 profilin YOR127W RGA1 RHO-type GTPase-activating protein for CDC42P YOR149C SMP3 protein kinase C pathway protein YOR156C NFI1 interacts with CDC12P in 2-hybrid assay YOR181W LAS17 component of actin cortical patches YOR188W MSB1 morphogenesis-related protein YOR198C BFR1 maintenance of normal ploidy YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YOR231W MKK1 ser/thr protein kinase YOR304C-A YOR304C-A similarity to mouse apolipoprotein A-IV precursor YOR326W MYO2 myosin heavy chain YPL032C SVL3 strong similarity to PAM1P YPL049C DIG1 MAP kinase-associated protein, down-regulator of invasive growth and mating YPL057C SUR1 required for mannosylation of sphingolipids YPL115C BEM3 GTPase-activating protein for CDC42P and RHO1P YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL161C BEM4 bud emergence protein YPL242C IQG1 involved in cytokinesis, has similarity to mammalian IQGAP proteins YPL255W BBP1 cell division control protein YPL256C CLN2 cyclin, G1/S-specific YPR032W SRO7 polarized exocytosis by regulating SNARE function YPR052C NHP6A nonhistone chromosomal protein related to mammalian HMG1 YPR119W CLB2 cyclin, G2/M-specific YPR122W AXL1 protease YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins pheromone response, mating-type determination, sex-specific proteins (160 ORFs) 14.04.03.03 160 YAL029C MYO4 myosin heavy chain, unconventional (class V) isoform YAL041W CDC24 GTP/GDP exchange factor for CDC42P YAR007C RFA1 DNA replication factor A, 69 KD subunit YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBL028C YBL028C hypothetical protein - involved in mating-type regulation YBL052C SAS3 silencing protein YBR023C CHS3 chitin synthase III YBR040W FIG1 required for efficient mating YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR109C CMD1 calmodulin YBR130C SHE3 required for mother cell-specific expression of HO YBR200W BEM1 bud emergence mediator YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR289W SNF5 component of SWI/SNF transcription activator complex YCL027W FUS1 cell fusion protein YCL029C BIK1 nuclear fusion protein YCL032W STE50 pheromone response pathway protein YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCL066W HMLALPHA1 mating type regulatory protein, silenced copy at HML YCL067C HMLALPHA2 mating type regulatory protein, silenced copy at HML YCR002C CDC10 cell division control protein YCR009C RVS161 similarity to human amphiphysin and RVS167P YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR039C MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040W MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCR089W FIG2 required for efficient mating YCR096C A2 mating type regulatory protein, silenced copy at HMR locus YCR097W A1 mating type regulatory protein, silenced copy at HMR locus YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL159W STE7 ser/thr/tyr protein kinase of MAP kinase kinase family YDL227C HO homothallic switching endonuclease YDR004W RAD57 DNA repair protein YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR073W SNF11 component of SWI/SNF transcription activator complex YDR076W RAD55 DNA repair protein YDR085C AFR1 involved in morphogenesis of the mating projection YDR103W STE5 pheromone signal transduction pathway protein YDR143C SAN1 mating-type regulation protein YDR146C SWI5 transcription factor YDR191W HST4 member of the SIR2P family of putative NAD-dependent histone deacetylases YDR227W SIR4 silencing regulatory and DNA-repair protein YDR261C EXG2 exo-beta-1,3-glucanase minor isoform YDR264C AKR1 ankyrin repeat-containing protein YDR309C GIC2 CDC42 GTPase-binding protein YDR312W SSF2 protein with a potential role in mating YDR335W MSN5 multicopy supressor of SNF1 mutation YDR392W SPT3 general transcriptional adaptor or co-activator YDR461W MFA1 mating pheromone a-factor 1 YDR480W DIG2 MAP kinase-associated protein, down-regulator of invasive growth and mating YER020W GPA2 guanine nucleotide-binding regulatory protein YER068W MOT2 transcriptional repressor YER075C PTP3 protein tyrosine phosphatase YER095W RAD51 DNA repair protein YER100W UBC6 E2 ubiquitin-conjugating enzyme YER149C PEA2 involved in oriented growth toward mating partner YFL026W STE2 pheromone alpha-factor receptor YGL032C AGA2 a-agglutinin binding subunit YGL089C MF(ALPHA)2 mating pheromone alpha-2 factor YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL178W MPT5 multicopy suppressor of POP2 YGR023W MTL1 potential cell wall stres sensor YGR040W KSS1 ser/thr protein kinase of the MAP kinase family YGR217W CCH1 calcium channel protein YGR238C KEL2 involved in cell fusion and morphogenesis YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHL025W SNF6 global transcription activator YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR061C GIC1 CDC42 GTPase-binding protein YHR066W SSF1 mating protein YHR084W STE12 transcriptional activator YHR107C CDC12 septin YHR118C ORC6 origin recognition complex, 50 KD subunit YHR146W CRP1 similarity to pheromone-response G-protein MDG1P YHR158C KEL1 involved in cell fusion and morphology YIL015W BAR1 barrierpepsin precursor YIL034C CAP2 F-actin capping protein, beta subunit YIL047C SYG1 member of the major facilitator superfamily YJL078C PRY3 strong similarity to the plant PR-1 class of pathogen related proteins YJL079C PRY1 strong similarity to the plant PR-1 class of pathogen related proteins YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJL170C ASG7 weak similarity to Helicobacter pylori endonuclease III YJL174W KRE9 cell wall synthesis protein YJL176C SWI3 transcription regulatory protein YJL212C OPT1 oligopeptide transporter specific for tetra- and pentapeptides YJR004C SAG1 alpha-agglutinin YJR076C CDC11 septin YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YJR117W STE24 zinc metallo-protease YKL007W CAP1 F-actin capping protein alpha subunit YKL104C GFA1 glucosamine--fructose-6-phosphate transaminase YKL117W SBA1 Hsp90 (Ninety) Associated Co-chaperone YKL130C SHE2 required for mother cell-specific expression of HO YKL178C STE3 pheromone a-factor receptor YKL185W ASH1 negative regulator of HO transcription YKL190W CNB1 calcineurin B, regulatory subunit YKL209C STE6 ATP-binding cassette transporter protein YKR101W SIR1 silencing regulatory protein YLL004W ORC3 origin recognition complex, 62 kDa subunit YLL021W SPA2 involved in cell polarity YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR229C CDC42 GTP-binding protein of RAS superfamily YLR300W EXG1 exo-beta-1,3-glucanase (I/II), major isoform YLR314C CDC3 cell division control protein YLR330W CHS5 chitin synthesis protein YLR332W MID2 mating process protein YLR362W STE11 ser/thr protein kinase of the MEKK family YLR371W ROM2 GDP/GTP exchange factor for RHO1P YLR389C STE23 protease involved in a-factor processing YLR433C CNA1 calcineurin B, catalytic subunit YLR441C RPS1A ribosomal protein S3a.e YLR442C SIR3 silencing regulatory and DNA-repair protein YLR452C SST2 involved in desensitization to alpha-factor pheromone YML032C RAD52 recombination and DNA repair protein YML057W CMP2 calcineurin B, catalytic subunit YML065W ORC1 origin recognition complex, 104 KD subunit YMR022W QRI8 E2 ubiquitin-conjugation enzyme YMR043W MCM1 transcription factor of the MADS box family YMR052W FAR3 involved in pheromone-mediated cell cycle arrest YMR065W KAR5 nuclear fusion protein YMR127C SAS2 involved in silencing at HMR YMR232W FUS2 required for cell fusion during mating YMR263W SAP30 subunit of the histone deacetylase B complex YNL053W MSG5 dual-specifity protein phosphatase YNL079C TPM1 tropomyosin 1 YNL084C END3 required for endocytosis and cytoskeletal organization YNL145W MFA2 mating pheromone a-factor 2 YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YNL188W KAR1 cell division control protein YNL192W CHS1 chitin synthase I YNL236W SIN4 global regulator protein YNL238W KEX2 endoproteinase of late golgi compartment YNL243W SLA2 cytoskeleton assembly control protein YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL271C BNI1 regulator of budding YNL291C MID1 involved in Ca2+ influx during mating YNL307C MCK1 ser/thr/tyr protein kinase YNL330C RPD3 histone deacetylase B YNR044W AGA1 a-agglutinin anchor subunit YOL004W SIN3 transcription regulatory protein YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL068C HST1 silencing protein YOR035C SHE4 required for mother cell-specific gene expression YOR127W RGA1 RHO-type GTPase-activating protein for CDC42P YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YOR219C STE13 type IV dipeptidyl aminopeptidase YOR281C PLP2 phosducin homologue, likely to be involved in regulation of pheromone response YOR290C SNF2 component of SWI/SNF global transcription activator complex YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL049C DIG1 MAP kinase-associated protein, down-regulator of invasive growth and mating YPL115C BEM3 GTPase-activating protein for CDC42P and RHO1P YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL161C BEM4 bud emergence protein YPL187W MFALPHA1 mating pheromone alpha-1 precursor YPL240C HSP82 heat shock protein YPL256C CLN2 cyclin, G1/S-specific YPR075C OPY2 pheromone resistant yeast 2 YPR141C KAR3 kinesin-related protein YPR161C SGV1 ser/thr protein kinase YPR162C ORC4 origin recognition complex, 56 KD subunit sporulation and germination (114 ORFs) 14.04.03.05 114 YAL009W SPO7 meiotic protein YBL015W ACH1 acetyl-CoA hydrolase YBL066C SEF1 putative transcription factor YBR023C CHS3 chitin synthase III YBR045C GIP1 GLC7-interacting protein YBR057C MUM2 meiotic protein YBR078W ECM33 involved in cell wall biogenesis and architecture YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR148W YSW1 spore-specific protein YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YCL048W YCL048W strong similarity to sporulation-specific protein SPS2P YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR048W ARE1 acyl-CoA sterol acyltransferase YCR086W CSM1 involved in nuclear migration YDL116W NUP84 nuclear pore protein YDL240W LRG1 GTPase-activating protein of the rho/rac family YDR055W PST1 strong similarity to SPS2 protein YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR069C DOA4 ubiquitin-specific protease YDR104C SPO71 protein involved in spore wall formation YDR108W GSG1 sporulation specific protein YDR173C ARG82 arginine metabolism transcription factor YDR177W UBC1 E2 ubiquitin-conjugating enzyme YDR182W CDC1 cell division control protein YDR218C SPR28 septin-related sporulation protein YDR261C EXG2 exo-beta-1,3-glucanase minor isoform YDR402C DIT2 cytochrome P450 56 YDR403W DIT1 spore wall maturation protein YDR522C SPS2 sporulation-specific protein YDR523C SPS1 ser/thr protein kinase YER012W PRE1 20S proteasome subunit C11(beta4) YER044C-A MEI4 meiosis-specific protein YER096W SHC1 sporulation specific protein YER115C SPR6 sporulation-specific protein YER125W RSP5 hect domain E3 ubiquitin-protein ligase YER132C PMD1 negative regulator of early meiotic expression YFL009W CDC4 cell division control protein YGL054C ERV14 ER-derived Vesicles YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL090W LIF1 DNA ligase IV interacting factor YGL100W SEH1 nuclear pore protein YGL106W MLC1 MYO2P light chain YGL180W APG1 essential for autophagocytosis YGL192W IME4 positive transcription factor for IME2 YGL197W MDS3 negative regulator of early meiotic expression YGR032W GSC2 1,3-beta-D-glucan synthase subunit YGR059W SPR3 sporulation-specific septin YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YGR225W AMA1 required for sporulation YGR253C PUP2 20S proteasome subunit(alpha5) YHL024W RIM4 No sporulation YHR004C NEM1 required for nuclear morphology YHR119W SET1 involved in chromatin-mediated gene regulation YHR139C SPS100 sporulation-specific wall maturation protein YHR152W SPO12 sporulation protein YHR153C SPO16 sporulation protein YHR184W SSP1 essential for meiosis and spore formation YHR185C PFS1 similarity to S. pombe TEA1P YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL073C SPO22 weak similarity to mouse polycystic kidney disease-related protein YIL084C SDS3 transcriptional regulator YIL099W SGA1 sporulation specific glucan 1,4-alpha-glucosidase YIL124W AYR1 1-Acyldihydroxyacetone-phosphate reductase YIR026C YVH1 protein tyrosine phosphatase YJL001W PRE3 20S proteasome subunit (beta1) YJL005W CYR1 adenylate cyclase YJL106W IME2 ser/thr protein kinase YJL146W IDS2 IME2-dependent signaling protein YJR042W NUP85 nuclear pore protein YJR094C IME1 transcription factor required for sporulation YKL165C MCD4 sporulation protein YKR031C SPO14 phospholipase D YKR082W NUP133 nuclear pore protein YLL039C UBI4 ubiquitin YLR025W SNF7 class E Vps protein YLR300W EXG1 exo-beta-1,3-glucanase (I/II), major isoform YLR307W CDA1 sporulation-specific chitin deacetylase YLR308W CDA2 sporulation-specific chitin deacetylase YLR399C BDF1 sporulation protein YML115C VAN1 vanadate resistance protein YMR013C SEC59 dolichol kinase YMR017W SPO20 DBF2P interacting protein YMR043W MCM1 transcription factor of the MADS box family YMR063W RIM9 regulator for sporulation and invasive growth YMR154C RIM13 calpain-like cysteine protease YMR263W SAP30 subunit of the histone deacetylase B complex YNL012W SPO1 transcriptional regulator involved in sporulation YNL098C RAS2 GTP-binding protein YNL192W CHS1 chitin synthase I YNL196C SLZ1 sporulation-specific protein YNL204C SPS18 sporulation-specific zinc-finger protein YNL225C CNM67 involved in cytokinesis YNL236W SIN4 global regulator protein YNL242W APG2 required for sporulation YNL307C MCK1 ser/thr/tyr protein kinase YNL330C RPD3 histone deacetylase B YNR019W ARE2 acyl-CoA sterol acyltransferase YNR052C POP2 required for glucose derepression YOL004W SIN3 transcription regulatory protein YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL052C SPE2 adenosylmethionine decarboxylase precursor YOL139C CDC33 translation initiation factor eIF4E YOR005C DNL4 DNA ligase IV YOR075W UFE1 syntaxin (T-SNARE) of the ER YOR190W SPR1 exo-1,3-beta-glucanase precursor YOR208W PTP2 protein-tyrosine-phosphatase YOR298W MUM3 required for meiosis YOR313C SPS4 sporulation-specific protein YOR361C PRT1 translation initiation factor eIF3 subunit YPL046C ELC1 Elongin C transcription elongation factor YPL240C HSP82 heat shock protein YPR007C SPO69 protein required for meiosis and sporulation YPR054W SMK1 sporulation-specific MAP kinase YPR103W PRE2 20S proteasome subunit (beta5) cell death (10 ORFs) 14.10 10 YDR227W SIR4 silencing regulatory and DNA-repair protein YHL003C LAG1 longevity-assurance protein YJL116C NCA3 involved in regulation of synthesis of ATP6P and Atp8p YJR089W BIR1 member of the inhibitor of apoptosis family, participate in chromosome segregation events YKL008C LAC1 protein required with LAG1P for ER-to-Golgi transport of GPI-anchored proteins YKR042W UTH1 involved in the aging process YMR190C SGS1 DNA helicase YNL098C RAS2 GTP-binding protein YOL025W LAG2 involved in determining longevity YOR101W RAS1 GTP-binding protein apoptosis (type I programmed cell death) (1 ORF) 14.10.02 1 YJR089W BIR1 member of the inhibitor of apoptosis family, participate in chromosome segregation events anti-apoptosis (1 ORF) 14.10.02.01 1 YJR089W BIR1 member of the inhibitor of apoptosis family, participate in chromosome segregation events cell aging (4 ORFs) 14.20 4 YGL178W MPT5 multicopy suppressor of POP2 YIL123W SIM1 involved in cell cycle regulation and aging YNL066W SUN4 strong similarity to YIL123w, UTH1P, NCA3P and C. wickerhamii beta-glucosidase protein YOR101W RAS1 GTP-binding protein TRANSPOSABLE ELEMENTS, VIRAL AND PLASMID PROTEINS (116 ORFs) 29 116 YCL074W YCL074W hypothetical protein - putative pseudo-TY5 YCL075W YCL075W hypothetical protein - putative pseudo-TY5 YCL076W YCL076W hypothetical protein - putative pseudo-TY5 YCR019W MAK32 necessary for structural stability of L-A dsRNA-containing particles YCR020C-A MAK31 involved in stability of L-A dsRNA-containing particles YDR289C RTT103 regulator of Ty1 Transposition YGR275W RTT102 Regulator of Ty1 Transposition YIL080W YIL080W strong similarity to other TY3B proteins YJL047C RTT101 weak similarity to CDC53P YNL085W MKT1 required for propagation of M2 dsRNA satellite of L-A virus Q0050 AI1 COX1 intron 1 protein Q0055 AI2 COX1 intron 2 protein TY1A_A TY1A TY1A protein TY1A_BL TY1A TY1A protein TY1A_BR TY1A TY1A protein TY1A_DR1 TY1A TY1A protein TY1A_DR2 TY1A TY1A protein TY1A_DR3 TY1A TY1A protein TY1A_DR4 TY1A TY1A protein TY1A_DR5 TY1A TY1A protein TY1A_DR6 TY1A TY1A protein TY1A_ER1 TY1A TY1A protein TY1A_ER2 TY1A TY1A protein TY1A_GR1 TY1A TY1A protein TY1A_GR2 TY1A TY1A protein TY1A_GR3 TY1A TY1A protein TY1A_H TY1A TY1A protein TY1A_JR1 TY1A TY1A protein TY1A_JR2 TY1A TY1A protein TY1A_LR1 TY1A TY1A protein TY1A_LR2 TY1A TY1A protein TY1A_LR3 TY1A TY1A protein TY1A_LR4 TY1A TY1A protein TY1A_ML1 TY1A TY1A protein TY1A_ML2 TY1A TY1A protein TY1A_MR1 TY1A TY1A protein TY1A_MR2 TY1A TY1A protein TY1A_NL1 TY1A TY1A protein TY1A_NL2 TY1A TY1A protein TY1A_OL TY1A TY1A protein TY1A_OR TY1A TY1A protein TY1A_PL TY1A TY1A protein TY1A_PR1 TY1A TY1A protein TY1A_PR2 TY1A TY1A protein TY1A_PR3 TY1A TY1A protein TY1B_A TY1B Ty1B protein TY1B_A_LR4 TY1B TY1B protein TY1B_BL TY1B TY1B protein TY1B_BR TY1B TY1B protein TY1B_B_LR4 TY1B TY1B protein TY1B_DR1 TY1B TY1B protein TY1B_DR2 TY1B truncated TY1B TY1B_DR3 TY1B TY1B protein TY1B_DR4 TY1B TY1B protein TY1B_DR5 TY1B TY1B protein TY1B_DR6 TY1B TY1B protein TY1B_ER1 TY1B TY1B protein TY1B_ER2 TY1B TY1B protein TY1B_GR1 TY1B TY1B protein TY1B_GR2 TY1B TY1B protein TY1B_GR3 TY1B TY1B protein TY1B_H TY1B TY1B TY1B_JR1 TY1B TY1B protein TY1B_JR2 TY1B TY1B protein TY1B_LR1 TY1B TY1B protein TY1B_LR2 TY1B TY1B protein TY1B_LR3 TY1B TY1B protein TY1B_ML1 TY1B TY1B protein TY1B_ML2 TY1B TY1B protein TY1B_MR1 TY1B TY1B protein TY1B_MR2 TY1B TY1B protein TY1B_NL1 TY1B TY1B protein TY1B_NL2 TY1B TY1B protein TY1B_OL TY1B TY1B protein TY1B_OR TY1B TY1B protein TY1B_PL TY1B TY1B protein TY1B_PR1 TY1B TY1B protein TY1B_PR2 TY1B TY1B protein TY1B_PR3 TY1B TY1B protein TY2A_B TY2A TY2A protein TY2A_C TY2A TY2A protein TY2A_DR1 TY2A TY2A protein TY2A_DR2 TY2A TY2A protein TY2A_DR3 TY2A TY2A protein TY2A_F TY2A TY2A protein TY2A_GR1 TY2A putative pseudo-TY2A TY2A_GR2 TY2A TY2A protein TY2A_LR1 TY2A TY2A protein TY2A_LR2 TY2A TY2A protein TY2A_N TY2A TY2A protein TY2A_OR1 TY2A TY2A protein TY2A_OR2 TY2A TY2A protein TY2B_A_GR1 TY2B putative pseudo-TY2B TY2B_B TY2B TY2B protein TY2B_B_GR1 TY2B putative pseudo-TY2B TY2B_C TY2B TY2B protein TY2B_DR1 TY2B TY2B protein TY2B_DR2 TY2B TY2B protein TY2B_DR3 TY2B TY2B protein TY2B_F TY2B TY2B protein TY2B_GR2 TY2B TY2B protein TY2B_LR1 TY2B TY2B protein TY2B_LR2 TY2B TY2B protein TY2B_N TY2B TY2B protein TY2B_OR1 TY2B TY2B protein TY2B_OR2 TY2B TY2B protein TY3A_G TY3A TY3A protein TY3A_I TY3A TY3A protein TY3B_G TY3B TY3B protein TY3B_I TY3B TY3B protein TY4A_H TY4A TY4A protein TY4A_J TY4A TY4A protein TY4A_P TY4A probably inactive TY4A TY4B_H TY4B TY4B protein TY4B_J TY4B TY4B protein TY4B_P TY4B probably inactive TY4B other transposable elements, viral and plasmid proteins (3 ORFs) 29.99 3 YDR289C RTT103 regulator of Ty1 Transposition YGR275W RTT102 Regulator of Ty1 Transposition YJL047C RTT101 weak similarity to CDC53P CONTROL OF CELLULAR ORGANIZATION (209 ORFs) 30 209 YAL009W SPO7 meiotic protein YAL054C ACS1 acetyl-CoA synthetase YAL059W ECM1 involved in cell wall biosynthesis YAL062W GDH3 NADP-glutamate dehydrogenase YBL001C ECM15 involved in cell wall biogenesis and architecture YBL039C URA7 CTP synthase 1 YBL043W ECM13 involved in cell wall structure of biosynthesis YBL050W SEC17 transport vesicle fusion protein YBL061C SKT5 protoplast regeneration and killer toxin resistance protein YBL088C TEL1 telomere length control protein YBL101C ECM21 involved in cell wall biogenesis and architecture YBL106C SRO77 polarized exocytosis by regulating SNARE function YBR002C RER2 cis-prenyltransferase, a key enzyme in dolichol synthesis YBR023C CHS3 chitin synthase III YBR065C ECM2 involved in cell wall biogenesis and architecture YBR076W ECM8 involved in cell wall structure or biosynthesis YBR078W ECM33 involved in cell wall biogenesis and architecture YBR091C MRS5 subunit of the TIM22-complex YBR123C TFC1 TFIIIC (transcription initiation factor) subunit, 95 kD YBR152W SPP381 Suppressor of Pre-mRNA Processing mutant YBR176W ECM31 involved in cell wall biogenesis and architecture YBR179C FZO1 required for biogenesis of mitochondria YBR195C MSI1 chromatin assembly complex, subunit p50 YBR217W APG12 component of the autophagic system YCL001W RER1 required for correct localization of SEC12P YCL004W PGS1 phosphatidylglycerophosphate synthase YCL007C CWH36 affects the mannoprotein layer of the cell wall YCR071C IMG2 required for Integrity of Mitochondrial Genome YDL006W PTC1 protein serine/threonine phosphatase 2c YDL055C PSA1 mannose-1-phosphate guanyltransferase YDL103C QRI1 UDP-N-acetylglucosamine pyrophosphorylase YDL137W ARF2 GTP-binding protein of the ARF family YDL138W RGT2 suppressor of SNF3 mutant YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL234C GYP7 GTPase-activating protein for YPT7P YDR060W MAK21 protein required for 60S ribosomal subunit biogenesis YDR069C DOA4 ubiquitin-specific protease YDR072C IPT1 mannosyl diphosphorylinositol ceramide synthase YDR125C ECM18 involved in cell wall biogenesis and architecture YDR142C PEX7 peroxisomal import protein - peroxin YDR181C SAS4 involved in silencing at telomeres YDR184C ATC1 binds Aip3p YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR231C COX20 in the maturation and assembly of cytochrome oxidase involved protein YDR260C SWM1 developmentally regulated gene, is required for spore wall assembly YDR356W NUF1 spindle pole body component YDR402C DIT2 cytochrome P450 56 YDR414C ERD1 required for retention of luminal ER proteins YDR446W ECM11 involved in cell wall biogenesis and architecture YDR468C TLG1 member of the syntaxin family of t-SNAREs YDR483W KRE2 alpha-1,2-mannosyltransferase YEL003W GIM4 Gim complex component YEL013W VAC8 required for vacuole inheritance and protein targeting from the cytoplasm to vacuole YEL020W-A TIM9 essential subunit of the TIM22-complex for mitochondrial protein import YEL030W ECM10 heat shock protein of HSP70 family YEL037C RAD23 nucleotide excision repair protein (ubiquitin-like protein) YEL040W UTR2 cell wall protein YEL059C-A SOM1 required for mitochondrial IMP1 peptidase function YER016W BIM1 binding to microtubules YER150W SPI1 Stationary Phase Induced YER176W ECM32 DNA dependent ATPase/DNA helicase B YFR019W FAB1 phosphatidylinositol 3-phosphate 5-kinase YGL016W KAP122 Member of the karyopherin-beta family, nuclear import YGL027C CWH41 ER glucosidase I YGL029W CGR1 Coiled-coil protein, may play a role in ribosome biogenesis YGL095C VPS45 vacuolar protein sorting-associated protein YGL142C GPI10 required for Glycosyl Phosphatdyl Inositol synthesis YGL210W YPT32 small GTP-binding protein essential for Golgi function YGL212W VAM7 vacuolar morphogenesis protein YGL238W CSE1 importin-beta-like protein YGL241W KAP114 Member of the karyopherin-beta family, nuclear import YGR008C STF2 ATPase stabilizing factor YGR036C CAX4 required for full levels of dolichol-linked oligosaccharides in the endoplasmic reticulum YGR078C PAC10 GIM4 - Gim complex component YGR195W SKI6 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YGR239C PEX21 peroxin, essential for peroxisomal targeting by the PTS2 pathway YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHL028W WSC4 Cell wall integrity and stress response component 4 YHL030W ECM29 involved in cell wall biogenesis and architecture YHL043W ECM34 involved in cell wall biogenesis and architecture YHR004C NEM1 required for nuclear morphology YHR005C-A MRS11 subunit of the TIM22-complex YHR012W VPS29 involved in vacuolar protein sorting YHR021W-A ECM12 probably involved in cell wall structure or biogenesis YHR061C GIC1 CDC42 GTPase-binding protein YHR102W KIC1 ser/thr protein kinase that interacts with CDC31P YHR119W SET1 involved in chromatin-mediated gene regulation YHR132C ECM14 involved in cell wall biogenesis and architecture YHR142W CHS7 control of protein export from the ER (like chitin synthase III) YHR160C PEX18 peroxin, essential for peroxisomal targeting by the PTS2 pathway YHR166C CDC23 subunit of anaphase-promoting complex (cyclosome) YHR171W APG7 component of the autophagic system YHR195W NVJ1 part of nucleus-vacuole junctions YIL009C-A EST3 subunit of the telomerase YIL051C MMF1 required for maintenance of mitochondrial DNA YIL065C FIS1 protein involved in mitochondrial division YIL072W HOP1 meiosis-specific protein YIL146C ECM37 involved in cell wall biogenesis and architecture YIL154C (IMP2) sugar utilization regulatory protein YIR004W DJP1 DnaJ-like protein involved specifically in peroxisomal protein import YIR006C PAN1 actin-cytoskeleton assembly protein YIR030C DCG1 involved in nitrogen-catabolite metabolism YJL033W HCA4 can suppress the U14 snoRNA rRNA processing function YJL074C SMC3 required for structural maintenance of chromosomes YJL081C ARP4 actin-related protein YJL154C VPS35 protein-sorting protein, vacuolar YJL165C HAL5 ser/thr protein kinase YJL194W CDC6 cell division control protein YJL201W ECM25 involved in cell wall biogenesis and architecture YJR060W CBF1 kinetochore protein YJR075W HOC1 suppressor of PKC1 YJR106W ECM27 involved in cell wall biogenesis and architecture YJR137C ECM17 involved in cell wall biogenesis and architecture YJR138W IML1 similarity to C.elegans hypothetical protein T08A11.1 YKL004W AUR1 aureobasidin-resistance protein YKL025C PAN3 component of the PAB1P-dependent poly(A) ribonuclease YKL093W MBR1 required for optimal growth on glycerol YKL179C YKL179C similarity to NUF1P YKL184W SPE1 ornithine decarboxylase YKL197C PEX1 peroxisomal assembly protein - peroxin YKL212W SAC1 recessive suppressor of secretory defect YKR004C ECM9 involved in cell wall biogenesis and architecture YKR008W RSC4 member of RSC complex, which remodels the structure of chromatin YKR009C FOX2 hydratase-dehydrogenase-epimerase, peroxisomal YKR048C NAP1 nucleosome assembly protein I YKR076W ECM4 involved in cell wall biogenesis and architecture YLR086W SMC4 Stable Maintenance of Chromosomes YLR110C CCW12 strong similarity to FLO1P YLR144C ACF2 necessary for cortical actin assembly YLR175W CBF5 putative rRNA pseuduridine synthase YLR182W SWI6 transcription factor YLR200W YKE2 Gim complex component YLR233C EST1 telomere elongation protein YLR249W YEF3 translation elongation factor eEF3 YLR263W RED1 meiosis-specific protein YLR288C MEC3 G2-specific checkpoint protein YLR299W ECM38 gamma-glutamyltransferase, involved in glutathione synthesis YLR309C IMH1 involved in vesicular transport YLR318W EST2 catalytic subunit of the telomerase YLR321C SFH1 subunit of the RSC complex YLR343W YLR343W strong similarity to GAS1P and C.albicans pH responsive protein YLR353W BUD8 budding protein YLR357W RSC2 member of RSC complex, which remodels the structure of chromatin YLR371W ROM2 GDP/GTP exchange factor for RHO1P YLR390W ECM19 involved in cell wall biogenesis and architecture YLR390W-A CCW14 Secretory Stress Response protein 1 YLR396C VPS33 vacuolar sorting protein YLR436C ECM30 involved in cell wall biogenesis and architecture YLR443W ECM7 involved in cell wall biogenesis and architecture YLR453C RIF2 RAP1P interacting factor 2 YLR457C NBP1 NAP1P-binding protein YML048W GSF2 involved in glucose repression YML094W GIM5 Gim complex component YML115C VAN1 vanadate resistance protein YMR012W CLU1 translation initiation factor eIF3 (p135 subunit) YMR072W ABF2 high mobility group protein YMR101C SRT1 cis-prenyltransferase homologue YMR128W ECM16 putative DEAH-box RNA helicase YMR131C RRB1 involved in the regulation of ribosome biosynthesis YMR165C SMP2 involved in plasmid maintenance, respiration and cell proliferation YMR176W ECM5 involved in cell wall biogenesis and architecture YMR224C MRE11 DNA repair and meiotic recombination protein YMR234W RNH1 ribonuclease H YMR307W GAS1 glycophospholipid-anchored surface glycoprotein YMR317W YMR317W similarity to mucins, glucan 1,4-alpha-glucosidase and exo-alpha-sialidase YNL020C ARK1 Actin Regulating Kinase YNL076W MKS1 pleiotropic regulatory factor YNL153C GIM3 Gim complex component YNL189W SRP1 karyopherin-alpha or importin YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL218W MGS1 similarity to E.coli hypothetical protein in serS 5'region YNL219C ALG9 mannosyltransferase YNL298W CLA4 ser/thr protein kinase YNR003C RPC34 DNA-directed RNA polymerase III, 34 KD subunit YNR030W ECM39 involved in cell wall biogenesis and architecture YNR031C SSK2 MAP kinase kinase kinase of the high osmolarity signal transduction pathway YOL007C CSI2 involved in chitin synthesis YOL018C TLG2 member of the syntaxin family of t-SNAREs YOL023W IFM1 translation initiation factor 2, mitochondrial YOL025W LAG2 involved in determining longevity YOL116W MSN1 transcriptional activator YOR030W DFG16 involved in invasive growth upon nitrogen starvation YOR092W ECM3 involved in cell wall biogenesis and architecture YOR109W INP53 phosphatidylinositol phosphate phosphatase YOR206W NOC2 crucial for intranuclear movement of ribosomal precursor particles YOR257W CDC31 spindle pole body component, centrin YOR326W MYO2 myosin heavy chain YOR367W SCP1 similarity to mammalian smooth muscle protein SM22 and chicken calponin alpha YPL021W ECM23 similarity to SRD1P YPL045W VPS16 vacuolar sorting protein YPL050C MNN9 required for complex N-glycosylation YPL053C KTR6 mannosylphosphate transferase YPL115C BEM3 GTPase-activating protein for CDC42P and RHO1P YPL132W COX11 cytochrome-c oxidase assembly protein YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL149W APG5 involved in autophagy and nutrient starvation YPL175W SPT14 N-acetylglucosaminyltransferase YPL259C APM1 AP-1 complex subunit, mu1 subunit, 54 KD YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YPR032W SRO7 polarized exocytosis by regulating SNARE function YPR069C SPE3 putrescine aminopropyltransferase (spermidine synthase) YPR141C KAR3 kinesin-related protein YPR155C NCA2 control of mitochondrial synthesis of ATP6P and Atp8p YPR159W KRE6 glucan synthase subunit YPR173C VPS4 vacuolar sorting protein Q0255 Q0255 similarity to Podospora cytb intron 1a and coII intron protein 2 cell wall (107 ORFs) 30.01 107 YAL054C ACS1 acetyl-CoA synthetase YAL059W ECM1 involved in cell wall biosynthesis YAL062W GDH3 NADP-glutamate dehydrogenase YBL001C ECM15 involved in cell wall biogenesis and architecture YBL039C URA7 CTP synthase 1 YBL043W ECM13 involved in cell wall structure of biosynthesis YBL061C SKT5 protoplast regeneration and killer toxin resistance protein YBL101C ECM21 involved in cell wall biogenesis and architecture YBR002C RER2 cis-prenyltransferase, a key enzyme in dolichol synthesis YBR023C CHS3 chitin synthase III YBR065C ECM2 involved in cell wall biogenesis and architecture YBR076W ECM8 involved in cell wall structure or biosynthesis YBR078W ECM33 involved in cell wall biogenesis and architecture YBR123C TFC1 TFIIIC (transcription initiation factor) subunit, 95 kD YBR176W ECM31 involved in cell wall biogenesis and architecture YCL004W PGS1 phosphatidylglycerophosphate synthase YCL007C CWH36 affects the mannoprotein layer of the cell wall YDL055C PSA1 mannose-1-phosphate guanyltransferase YDL103C QRI1 UDP-N-acetylglucosamine pyrophosphorylase YDL138W RGT2 suppressor of SNF3 mutant YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL188C PPH22 protein ser/thr phosphatase PP2A-2 YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDR072C IPT1 mannosyl diphosphorylinositol ceramide synthase YDR125C ECM18 involved in cell wall biogenesis and architecture YDR402C DIT2 cytochrome P450 56 YDR414C ERD1 required for retention of luminal ER proteins YDR446W ECM11 involved in cell wall biogenesis and architecture YDR483W KRE2 alpha-1,2-mannosyltransferase YEL030W ECM10 heat shock protein of HSP70 family YEL037C RAD23 nucleotide excision repair protein (ubiquitin-like protein) YEL040W UTR2 cell wall protein YER150W SPI1 Stationary Phase Induced YER176W ECM32 DNA dependent ATPase/DNA helicase B YGL027C CWH41 ER glucosidase I YGL142C GPI10 required for Glycosyl Phosphatdyl Inositol synthesis YGR008C STF2 ATPase stabilizing factor YGR036C CAX4 required for full levels of dolichol-linked oligosaccharides in the endoplasmic reticulum YGR195W SKI6 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YHL028W WSC4 Cell wall integrity and stress response component 4 YHL030W ECM29 involved in cell wall biogenesis and architecture YHL043W ECM34 involved in cell wall biogenesis and architecture YHR021W-A ECM12 probably involved in cell wall structure or biogenesis YHR102W KIC1 ser/thr protein kinase that interacts with CDC31P YHR119W SET1 involved in chromatin-mediated gene regulation YHR132C ECM14 involved in cell wall biogenesis and architecture YHR142W CHS7 control of protein export from the ER (like chitin synthase III) YIL146C ECM37 involved in cell wall biogenesis and architecture YIL154C (IMP2) sugar utilization regulatory protein YIR030C DCG1 involved in nitrogen-catabolite metabolism YJL033W HCA4 can suppress the U14 snoRNA rRNA processing function YJL165C HAL5 ser/thr protein kinase YJL201W ECM25 involved in cell wall biogenesis and architecture YJR075W HOC1 suppressor of PKC1 YJR106W ECM27 involved in cell wall biogenesis and architecture YJR137C ECM17 involved in cell wall biogenesis and architecture YKL025C PAN3 component of the PAB1P-dependent poly(A) ribonuclease YKL184W SPE1 ornithine decarboxylase YKR004C ECM9 involved in cell wall biogenesis and architecture YKR009C FOX2 hydratase-dehydrogenase-epimerase, peroxisomal YKR076W ECM4 involved in cell wall biogenesis and architecture YLR110C CCW12 strong similarity to FLO1P YLR182W SWI6 transcription factor YLR249W YEF3 translation elongation factor eEF3 YLR288C MEC3 G2-specific checkpoint protein YLR299W ECM38 gamma-glutamyltransferase, involved in glutathione synthesis YLR343W YLR343W strong similarity to GAS1P and C.albicans pH responsive protein YLR353W BUD8 budding protein YLR371W ROM2 GDP/GTP exchange factor for RHO1P YLR390W ECM19 involved in cell wall biogenesis and architecture YLR390W-A CCW14 Secretory Stress Response protein 1 YLR436C ECM30 involved in cell wall biogenesis and architecture YLR443W ECM7 involved in cell wall biogenesis and architecture YML048W GSF2 involved in glucose repression YML115C VAN1 vanadate resistance protein YMR101C SRT1 cis-prenyltransferase homologue YMR128W ECM16 putative DEAH-box RNA helicase YMR165C SMP2 involved in plasmid maintenance, respiration and cell proliferation YMR176W ECM5 involved in cell wall biogenesis and architecture YMR224C MRE11 DNA repair and meiotic recombination protein YMR234W RNH1 ribonuclease H YMR307W GAS1 glycophospholipid-anchored surface glycoprotein YMR317W YMR317W similarity to mucins, glucan 1,4-alpha-glucosidase and exo-alpha-sialidase YNL076W MKS1 pleiotropic regulatory factor YNL219C ALG9 mannosyltransferase YNR003C RPC34 DNA-directed RNA polymerase III, 34 KD subunit YNR030W ECM39 involved in cell wall biogenesis and architecture YNR031C SSK2 MAP kinase kinase kinase of the high osmolarity signal transduction pathway YOL007C CSI2 involved in chitin synthesis YOL023W IFM1 translation initiation factor 2, mitochondrial YOL025W LAG2 involved in determining longevity YOL116W MSN1 transcriptional activator YOR030W DFG16 involved in invasive growth upon nitrogen starvation YOR092W ECM3 involved in cell wall biogenesis and architecture YOR109W INP53 phosphatidylinositol phosphate phosphatase YOR257W CDC31 spindle pole body component, centrin YPL021W ECM23 similarity to SRD1P YPL045W VPS16 vacuolar sorting protein YPL050C MNN9 required for complex N-glycosylation YPL053C KTR6 mannosylphosphate transferase YPL132W COX11 cytochrome-c oxidase assembly protein YPL140C MKK2 protein kinase of the map kinase kinase (MEK) family YPL175W SPT14 N-acetylglucosaminyltransferase YPL268W PLC1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase YPR069C SPE3 putrescine aminopropyltransferase (spermidine synthase) YPR159W KRE6 glucan synthase subunit plasma membrane (1 ORF) 30.02 1 YJL194W CDC6 cell division control protein cytoplasm (1 ORF) 30.03 1 YDR142C PEX7 peroxisomal import protein - peroxin cytoskeleton (23 ORFs) 30.04 23 YBL106C SRO77 polarized exocytosis by regulating SNARE function YDR184C ATC1 binds Aip3p YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YEL003W GIM4 Gim complex component YGR078C PAC10 GIM4 - Gim complex component YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHR061C GIC1 CDC42 GTPase-binding protein YHR166C CDC23 subunit of anaphase-promoting complex (cyclosome) YIR006C PAN1 actin-cytoskeleton assembly protein YKL004W AUR1 aureobasidin-resistance protein YKL179C YKL179C similarity to NUF1P YKL212W SAC1 recessive suppressor of secretory defect YLR144C ACF2 necessary for cortical actin assembly YLR175W CBF5 putative rRNA pseuduridine synthase YLR200W YKE2 Gim complex component YLR371W ROM2 GDP/GTP exchange factor for RHO1P YML094W GIM5 Gim complex component YNL020C ARK1 Actin Regulating Kinase YNL153C GIM3 Gim complex component YNL298W CLA4 ser/thr protein kinase YOR367W SCP1 similarity to mammalian smooth muscle protein SM22 and chicken calponin alpha YPL115C BEM3 GTPase-activating protein for CDC42P and RHO1P YPR032W SRO7 polarized exocytosis by regulating SNARE function endoplasmic reticulum (3 ORFs) 30.07 3 YCL001W RER1 required for correct localization of SEC12P YDR468C TLG1 member of the syntaxin family of t-SNAREs YJL154C VPS35 protein-sorting protein, vacuolar Golgi (3 ORFs) 30.08 3 YDL137W ARF2 GTP-binding protein of the ARF family YPL259C APM1 AP-1 complex subunit, mu1 subunit, 54 KD YPR173C VPS4 vacuolar sorting protein intracellular transport vesicles (1 ORF) 30.09 1 YGL210W YPT32 small GTP-binding protein essential for Golgi function nucleus (31 ORFs) 30.10 31 YAL009W SPO7 meiotic protein YBL088C TEL1 telomere length control protein YBR152W SPP381 Suppressor of Pre-mRNA Processing mutant YBR195C MSI1 chromatin assembly complex, subunit p50 YDR181C SAS4 involved in silencing at telomeres YDR356W NUF1 spindle pole body component YER016W BIM1 binding to microtubules YGL016W KAP122 Member of the karyopherin-beta family, nuclear import YGL238W CSE1 importin-beta-like protein YGL241W KAP114 Member of the karyopherin-beta family, nuclear import YHR004C NEM1 required for nuclear morphology YHR119W SET1 involved in chromatin-mediated gene regulation YIL009C-A EST3 subunit of the telomerase YIL072W HOP1 meiosis-specific protein YJL074C SMC3 required for structural maintenance of chromosomes YJL081C ARP4 actin-related protein YJR060W CBF1 kinetochore protein YJR138W IML1 similarity to C.elegans hypothetical protein T08A11.1 YKR008W RSC4 member of RSC complex, which remodels the structure of chromatin YKR048C NAP1 nucleosome assembly protein I YLR086W SMC4 Stable Maintenance of Chromosomes YLR233C EST1 telomere elongation protein YLR263W RED1 meiosis-specific protein YLR318W EST2 catalytic subunit of the telomerase YLR321C SFH1 subunit of the RSC complex YLR357W RSC2 member of RSC complex, which remodels the structure of chromatin YLR453C RIF2 RAP1P interacting factor 2 YLR457C NBP1 NAP1P-binding protein YNL189W SRP1 karyopherin-alpha or importin YNL216W RAP1 DNA-binding protein with repressor and activator activity YPR141C KAR3 kinesin-related protein organization of chromosome structure (18 ORFs) 30.10.03 18 YBL088C TEL1 telomere length control protein YBR195C MSI1 chromatin assembly complex, subunit p50 YHR119W SET1 involved in chromatin-mediated gene regulation YIL009C-A EST3 subunit of the telomerase YIL072W HOP1 meiosis-specific protein YJL074C SMC3 required for structural maintenance of chromosomes YJL081C ARP4 actin-related protein YKR008W RSC4 member of RSC complex, which remodels the structure of chromatin YKR048C NAP1 nucleosome assembly protein I YLR086W SMC4 Stable Maintenance of Chromosomes YLR233C EST1 telomere elongation protein YLR263W RED1 meiosis-specific protein YLR318W EST2 catalytic subunit of the telomerase YLR321C SFH1 subunit of the RSC complex YLR357W RSC2 member of RSC complex, which remodels the structure of chromatin YLR453C RIF2 RAP1P interacting factor 2 YLR457C NBP1 NAP1P-binding protein YNL216W RAP1 DNA-binding protein with repressor and activator activity mitochondrion (17 ORFs) 30.16 17 YBR091C MRS5 subunit of the TIM22-complex YBR179C FZO1 required for biogenesis of mitochondria YCL004W PGS1 phosphatidylglycerophosphate synthase YCR071C IMG2 required for Integrity of Mitochondrial Genome YDL006W PTC1 protein serine/threonine phosphatase 2c YDR231C COX20 in the maturation and assembly of cytochrome oxidase involved protein YEL020W-A TIM9 essential subunit of the TIM22-complex for mitochondrial protein import YEL059C-A SOM1 required for mitochondrial IMP1 peptidase function YHR005C-A MRS11 subunit of the TIM22-complex YIL051C MMF1 required for maintenance of mitochondrial DNA YIL065C FIS1 protein involved in mitochondrial division YKL093W MBR1 required for optimal growth on glycerol YMR012W CLU1 translation initiation factor eIF3 (p135 subunit) YMR072W ABF2 high mobility group protein YNL218W MGS1 similarity to E.coli hypothetical protein in serS 5'region YPR155C NCA2 control of mitochondrial synthesis of ATP6P and Atp8p Q0255 Q0255 similarity to Podospora cytb intron 1a and coII intron protein 2 peroxisome (4 ORFs) 30.19 4 YGR239C PEX21 peroxin, essential for peroxisomal targeting by the PTS2 pathway YHR160C PEX18 peroxin, essential for peroxisomal targeting by the PTS2 pathway YIR004W DJP1 DnaJ-like protein involved specifically in peroxisomal protein import YKL197C PEX1 peroxisomal assembly protein - peroxin endosome (1 ORF) 30.22 1 YLR309C IMH1 involved in vesicular transport vacuole or lysosome (18 ORFs) 30.25 18 YBL050W SEC17 transport vesicle fusion protein YBR217W APG12 component of the autophagic system YDL234C GYP7 GTPase-activating protein for YPT7P YDR069C DOA4 ubiquitin-specific protease YDR468C TLG1 member of the syntaxin family of t-SNAREs YEL013W VAC8 required for vacuole inheritance and protein targeting from the cytoplasm to vacuole YFR019W FAB1 phosphatidylinositol 3-phosphate 5-kinase YGL095C VPS45 vacuolar protein sorting-associated protein YGL212W VAM7 vacuolar morphogenesis protein YHR012W VPS29 involved in vacuolar protein sorting YHR171W APG7 component of the autophagic system YHR195W NVJ1 part of nucleus-vacuole junctions YLR396C VPS33 vacuolar sorting protein YOL018C TLG2 member of the syntaxin family of t-SNAREs YOR326W MYO2 myosin heavy chain YPL045W VPS16 vacuolar sorting protein YPL149W APG5 involved in autophagy and nutrient starvation YPR173C VPS4 vacuolar sorting protein other control of cellular organization (7 ORFs) 30.99 7 YDR060W MAK21 protein required for 60S ribosomal subunit biogenesis YDR260C SWM1 developmentally regulated gene, is required for spore wall assembly YGL029W CGR1 Coiled-coil protein, may play a role in ribosome biogenesis YHR102W KIC1 ser/thr protein kinase that interacts with CDC31P YMR131C RRB1 involved in the regulation of ribosome biosynthesis YOR206W NOC2 crucial for intranuclear movement of ribosomal precursor particles YOR257W CDC31 spindle pole body component, centrin SUBCELLULAR LOCALISATION (2258 ORFs) 40 2258 YAL001C TFC3 TFIIIC (transcription initiation factor) subunit, 138 kD YAL003W EFB1 translation elongation factor eEF1beta YAL005C SSA1 heat shock protein of HSP70 family, cytosolic YAL009W SPO7 meiotic protein YAL010C MDM10 involved in mitochondrial morphology and inheritance YAL011W FUN36 weak similarity to Mus musculus p53-associated cellular protein YAL012W CYS3 cystathionine gamma-lyase YAL013W DEP1 regulator of phospholipid metabolism YAL019W FUN30 similarity to helicases of the SNF2/RAD54 family YAL020C ATS1 alpha-tubulin suppressor YAL021C CCR4 transcriptional regulator YAL023C PMT2 mannosyltransferase YAL025C MAK16 nuclear viral propagation protein YAL026C DRS2 P-type amino-phospholipids-ATPase YAL029C MYO4 myosin heavy chain, unconventional (class V) isoform YAL030W SNC1 synaptic vesicle-associated membrane protein YAL033W POP5 required for processing of tRNAs and rRNAs YAL034W-A MTW1 determining metaphase spindle length YAL035W FUN12 general translation factor eIF2 homolog YAL038W CDC19 pyruvate kinase YAL039C CYC3 holocytochrome-c synthase (cytochrome c heme lyase) YAL040C CLN3 cyclin, G1/S-specific YAL041W CDC24 GTP/GDP exchange factor for CDC42P YAL042W ERV46 component of copii vesicles involved in transport between the ER and golgi complex YAL043C PTA1 pre-tRNA processing protein / PF I subunit YAL044C GCV3 glycine decarboxylase, subunit H YAL051W OAF1 peroxisome proliferating transcription factor YAL054C ACS1 acetyl-CoA synthetase YAL058W CNE1 calnexin, involved in regulation of secretion YAL063C FLO9 strong similarity to FLO1P YAR007C RFA1 DNA replication factor A, 69 KD subunit YAR008W SEN34 tRNA splicing endonuclease gamma subunit YAR035W YAT1 carnitine acetyltransferase, mitochondrial YAR050W FLO1 cell wall protein involved in flocculation YAR071W PHO11 secreted acid phosphatase YBL002W HTB2 histone H2B.2 YBL003C HTA2 histone H2A.2 YBL005W PDR3 pleiotropic drug resistance regulatory protein YBL007C SLA1 cytoskeleton assembly control protein YBL008W HIR1 histone transcription regulator YBL013W FMT1 Methionyl-tRNA Transformylase YBL014C RRN6 RNA polymerase I specific transcription initiation factor YBL015W ACH1 acetyl-CoA hydrolase YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBL017C PEP1 vacuolar protein sorting/targeting protein YBL018C POP8 required for processing of tRNAs and rRNAs YBL020W RFT1 nuclear division protein YBL021C HAP3 CCAAT-binding factor subunit YBL022C PIM1 ATP-dependent protease, mitochondrial YBL023C MCM2 member of the MCM2P,MCM3P,CDC46P family YBL024W NCL1 tRNA (cytosine-5-)-methyltransferase YBL025W RRN10 RNA polymerase I-specific transcription initiation factor YBL026W LSM2 Sm-like (Lsm) protein YBL027W RPL19B 60S large subunit ribosomal protein L19.e YBL030C PET9 ADP/ATP carrier protein (MCF) YBL034C STU1 mitotic spindle protein YBL035C POL12 DNA-directed DNA polymerase alpha, 70 KD subunit YBL037W APL3 AP-2 complex subunit, alpha-adaptin, 113 KD YBL038W MRPL16 ribosomal protein of the large subunit, mitochondrial YBL039C URA7 CTP synthase 1 YBL040C ERD2 ER lumen protein-retaining receptor YBL041W PRE7 20S proteasome subunit(beta6) YBL042C FUI1 uridine transport protein YBL045C COR1 ubiquinol--cytochrome-c reductase 44K core protein YBL050W SEC17 transport vesicle fusion protein YBL054W YBL054W weak similarity to transforming protein (B-myb) YBL063W KIP1 kinesin-related protein YBL066C SEF1 putative transcription factor YBL072C RPS8A ribosomal protein S8.e YBL074C AAR2 A1 cistron splicing factor YBL075C SSA3 heat shock protein of HSP70 family, cytosolic YBL076C ILS1 isoleucyl-tRNA synthetase YBL078C AUT7 essential for autophagy YBL079W NUP170 nuclear pore protein YBL080C PET112 required to maintain rho+ mitochondrial DNA YBL082C RHK1 mannosyltransferase YBL084C CDC27 subunit of anaphase-promoting complex (cyclosome) YBL087C RPL23A 60S large subunit ribosomal protein L23.e YBL090W MRP21 Mitochondrial ribosomal protein YBL091C MAP2 methionine aminopeptidase, isoform 2 YBL092W RPL32 60S large subunit ribosomal protein L32.e YBL093C ROX3 transcription factor YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBL102W SFT2 suppressor of SED5 ts mutants YBL103C RTG3 bHLH/zip transcription factor that regulates CIT2 gene expression YBL105C PKC1 ser/thr protein kinase YBR003W COQ1 hexaprenyl pyrophosphate synthetase precursor YBR009C HHF1 histone H4 YBR010W HHT1 histone H3 YBR011C IPP1 inorganic pyrophosphatase, cytoplasmic YBR017C KAP104 beta-karyopherin YBR018C GAL7 UDP-glucose--hexose-1-phosphate uridylyltransferase YBR019C GAL10 UDP-glucose 4-epimerase YBR020W GAL1 galactokinase YBR021W FUR4 uracil permease YBR023C CHS3 chitin synthase III YBR024W SCO2 involved in stability of COX1P and COX2P YBR026C (MRF1) mitochondrial respiratory function protein YBR029C CDS1 CDP-diacylglycerol synthase YBR031W RPL4A ribosomal protein YBR034C HMT1 hnRNP arginine N-methyltransferase YBR036C CSG2 calcium dependent regulatory protein YBR037C SCO1 involved in stabilization of COX1P and COX2P YBR038W CHS2 chitin synthase II YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR040W FIG1 required for efficient mating YBR041W FAT1 very long-chain fatty acyl-CoA synthetase YBR044C TCM62 chaperone required for assembly of mitochondrial succinate dehydrogenase YBR048W RPS11B ribosomal protein S11.e.B YBR049C REB1 transcription factor YBR055C PRP6 snRNP(U4/U6)-associated splicing factor YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR067C TIP1 esterase YBR068C BAP2 leucine permease, high-affinity (S1) YBR069C TAT1 amino acid permease YBR072W HSP26 heat shock protein YBR079C RPG1 translation initiation factor eIF3 (p110 subunit) YBR080C SEC18 vesicular-fusion protein, functional homolog of NSF YBR081C SPT7 involved in alteration of transcription start site selection YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR083W TEC1 Ty transcription activator YBR084C-A RPL19A 60S large subunit ribosomal protein L19.e YBR084W MIS1 C1-tetrahydrofolate synthase precursor, mitochondrial YBR085W AAC3 ADP/ATP carrier protein (MCF) YBR087W RFC5 DNA replication factor C, 40 KD subunit YBR088C POL30 Proliferating Cell Nuclear Antigen (PCNA) YBR089C-A NHP6B nonhistone chromosomal protein YBR091C MRS5 subunit of the TIM22-complex YBR092C PHO3 constitutive acid phosphatase precursor YBR093C PHO5 repressible acid phosphatase precursor YBR097W VPS15 ser/thr protein kinase YBR102C EXO84 exocyst protein essential for secretion YBR103W SIF2 SIR4P interacting protein YBR104W YMC2 mitochondrial carrier protein (MCF) YBR105C VID24 required for vacuolar import and degradation of FBP1P YBR109C CMD1 calmodulin YBR110W ALG1 beta-mannosyltransferase YBR112C CYC8 general repressor of transcription YBR114W RAD16 nucleotide excision repair protein YBR115C LYS2 L-aminoadipate-semialdehyde dehydrogenase, large subunit YBR117C TKL2 transketolase 2 YBR118W TEF2 translation elongation factor eEF1 alpha-A chain, cytosolic YBR119W MUD1 U1 snRNP-specific A protein YBR120C CBP6 apo-cytochrome B pre-mRNA processing protein YBR121C GRS1 glycine--tRNA ligase YBR122C MRPL36 ribosomal protein YmL36 precursor, mitochondrial YBR123C TFC1 TFIIIC (transcription initiation factor) subunit, 95 kD YBR126C TPS1 alpha,alpha-trehalose-phosphate synthase, 56 KD subunit YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YBR130C SHE3 required for mother cell-specific expression of HO YBR133C HSL7 adapter in a regulatory pathway that relieves tyrosine phosphorylation of CDC28 YBR140C IRA1 inhibitory regulator protein of the ras-cyclic AMP pathway YBR142W MAK5 ATP-dependent RNA helicase YBR143C SUP45 translational release factor YBR146W MRPS9 ribosomal protein S9 precursor, mitochondrial YBR150C TBS1 weak similarity to transcription factors YBR154C RPB5 DNA-directed RNA polymerase I, II, III 25 KD subunit YBR158W CST13 weak similarity to TRCDSEMBL:AF176518_1 F-box protein FBL2; human YBR164C ARL1 ADP-ribosylation factor YBR166C TYR1 prephenate dehydrogenase (NADP+) YBR167C POP7 nuclear RNase P subunit YBR168W YBR168W weak similarity to hypothetical protein YLR324w YBR169C SSE2 heat shock protein of the HSP70 family YBR171W SEC66 ER protein-translocation complex subunit YBR172C SMY2 kinesin-related protein YBR173C UMP1 proteasome maturation factor YBR179C FZO1 required for biogenesis of mitochondria YBR181C RPS6B ribosomal protein S6.e YBR182C SMP1 MADS-box transcription factor YBR185C MBA1 respiratory chain assembly protein YBR186W PCH2 putative ATPase YBR189W RPS9B ribosomal protein S9.e.B YBR191W RPL21A ribosomal protein L21.e YBR192W RIM2 mitochondrial carrier protein (MCF) YBR193C MED8 transcriptional regulation mediator YBR196C PGI1 glucose-6-phosphate isomerase YBR198C TAF90 TFIID and SAGA subunit YBR200W BEM1 bud emergence mediator YBR201W DER1 involved in degradation proteins in the ER YBR202W CDC47 cell division control protein YBR204C YBR204C weak similarity to peroxisomal serine-active lipase YBR211C AME1 actin related protein YBR217W APG12 component of the autophagic system YBR218C PYC2 pyruvate carboxylase 2 YBR221C PDB1 pyruvate dehydrogenase (lipoamide) beta chain precursor YBR222C FAT2 AMP-binding protein, peroxisomal YBR227C MCX1 similarity to E.coli ATP-binding protein clpX YBR229C ROT2 glucosidase II, catalytic subunit YBR234C ARC40 ARP2/3 protein complex subunit, 40 kilodalton YBR236C ABD1 mRNA cap methyltransferase YBR237W PRP5 pre-mRNA processing RNA-helicase YBR239C YBR239C weak similarity to transcription factor PUT3P YBR240C THI2 regulator of the thiamine biosynthetic genes YBR243C ALG7 UDP-N-acetylglucosamine-1-phosphate transferase YBR247C ENP1 effects N-glycosylation YBR249C ARO4 2-dehydro-3-deoxyphosphoheptonate aldolase, tyrosine-inhibited YBR251W MRPS5 ribosomal protein S5, mitochondrial YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR254C TRS20 TRAPP subunit of 20 kDa involved in targeting and fusion of ER to golgi transport vesicles YBR257W POP4 involved in processing of tRNAs and rRNAs YBR263W SHM1 serine hydroxymethyltransferase precursor, mitochondrial YBR265W TSC10 3-ketosphinganine reductase YBR268W MRPL37 ribosomal protein YmL37, mitochondrial YBR275C RIF1 RAP1-interacting factor 1 YBR278W DPB3 DNA-directed DNA polymerase epsilon, subunit C YBR279W PAF1 DNA-directed RNA polymerase II regulator YBR282W MRPL27 ribosomal protein YmL27 precursor, mitochondrial YBR283C SSH1 involved in co-translational pathway of protein transport YBR286W APE3 vacuolar aminopeptidase Y YBR289W SNF5 component of SWI/SNF transcription activator complex YBR290W BSD2 metal homeostasis protein YBR291C CTP1 citrate transport protein, mitochondrial (MCF) YBR294W SUL1 high-affinity sulfate transport protein YBR297W MAL33 maltose fermentation regulatory protein YBR298C MAL31 maltose permease YBR299W MAL32 alpha-glucosidase YBR301W DAN3 cell wall mannoprotein YCL001W RER1 required for correct localization of SEC12P YCL004W PGS1 phosphatidylglycerophosphate synthase YCL009C ILV6 acetolactate synthase, regulatory subunit YCL011C GBP2 potential telomere-associated protein YCL014W BUD3 budding protein YCL017C NFS1 regulates Iron-Sulfur cluster proteins, cellular Iron uptake, andIron distribution YCL018W LEU2 beta-isopropyl-malate dehydrogenase YCL024W KCC4 kinase coordinate cell cycle progression with the organization of the peripheralcytoskeleton YCL025C AGP1 asparagine and glutamine permease YCL027W FUS1 cell fusion protein YCL029C BIK1 nuclear fusion protein YCL034W LSB5 possible role in the regulation of actin cytoskeletal organization YCL040W GLK1 aldohexose specific glucokinase YCL043C PDI1 protein disulfide-isomerase precursor YCL052C PBN1 required for post-translational processing of the protease B precursor PRB1P YCL054W SPB1 required for ribosome synthesis, putative methylase YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCL057W PRD1 proteinase yscD YCL059C KRR1 required for 40S ribosome biogenesis YCL066W HMLALPHA1 mating type regulatory protein, silenced copy at HML YCL067C HMLALPHA2 mating type regulatory protein, silenced copy at HML YCR002C CDC10 cell division control protein YCR003W MRPL32 ribosomal protein YmL32, mitochondrial YCR005C CIT2 citrate (si)-synthase, peroxisomal YCR009C RVS161 similarity to human amphiphysin and RVS167P YCR011C ADP1 ATP-dependent permease YCR012W PGK1 phosphoglycerate kinase YCR014C POL4 DNA polymerase YCR018C SRD1 nucleolar protein YCR021C HSP30 heat shock protein YCR024C-A PMP1 H+-ATPase subunit, plasma membrane YCR028C-A RIM1 ssDNA-binding protein, mitochondrial YCR031C RPS14A 40S Ribosomal protein S14.e YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR038C BUD5 GDP/GTP exchange factor for RSR1P/Bud1p YCR039C MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040W MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCR042C TSM1 component of TFIID complex YCR044C PER1 involved in manganese homeostasis YCR046C IMG1 ribosomal protein, mitochondrial YCR052W RSC6 subunit of the RSC complex YCR053W THR4 threonine synthase (o-p-homoserine p-lyase) YCR057C PWP2 periodic tryptophan protein YCR065W HCM1 transcription factor YCR066W RAD18 DNA repair protein YCR067C SED4 protein of the endoplasmic reticulum YCR069W SCC3 peptidyl-prolyl cis-trans isomerase precursor YCR072C YCR072C strong similarity to S. pombe trp-asp repeat containing protein YCR075C ERS1 intracellular protein transport protein YCR077C PAT1 topoisomerase II-associated protein YCR081W SRB8 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YCR083W TRX3 mitochondrial thioredoxin YCR084C TUP1 general transcription repressor YCR088W ABP1 actin-binding protein YCR089W FIG2 required for efficient mating YCR092C MSH3 DNA mismatch repair protein YCR093W CDC39 nuclear protein YCR096C A2 mating type regulatory protein, silenced copy at HMR locus YCR097W A1 mating type regulatory protein, silenced copy at HMR locus YCR098C GIT1 glycerophosphoinositol transporter YCR106W YCR106W similarity to transcription factor YDL003W MCD1 Mitotic Chromosome Determinant YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL005C MED2 transcriptional regulation mediator YDL007W RPT2 26S proteasome regulatory subunit YDL008W APC11 subunit of the anaphase promoting complex YDL014W NOP1 fibrillarin YDL017W CDC7 protein kinase YDL020C RPN4 26S proteasome subunit YDL022W GPD1 glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic YDL029W ARP2 actin-like protein YDL030W PRP9 pre-mRNA splicing factor (snRNA-associated protein) YDL035C GPR1 G-protein coupled receptor YDL040C NAT1 protein N-acetyltransferase subunit YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL043C PRP11 pre-mRNA splicing factor YDL044C MTF2 mitochondrial protein involved in mRNA splicing and protein synthesis YDL045C FAD1 flavin adenine dinucleotide (FAD) synthetase YDL045W-A MRP10 mitochondrial ribosomal protein YDL052C SLC1 fatty acyltransferase YDL056W MBP1 transcription factor, subunit of the MBF factor YDL058W USO1 intracellular protein transport protein YDL059C RAD59 recombination and DNA repair protein YDL061C RPS29B ribosomal protein S29.e.B YDL064W UBC9 E2 ubiquitin-conjugating enzyme YDL065C PEX19 required for biogenesis of peroxisomes - peroxin YDL066W IDP1 isocitrate dehydrogenase (NADP+), mitochondrial YDL067C COX9 cytochrome-c oxidase chain VIIA YDL069C CBS1 translational activator of COB mRNA YDL075W RPL31A 60S large subunit ribosomal protein L31.e YDL077C VAM6 vacuolar carboxypeptidase Y YDL078C MDH3 malate dehydrogenase, peroxisomal YDL081C RPP1A 60S large subunit acidic ribosomal protein a1 YDL082W RPL13A 60S large subunit ribosomal protein L13 YDL083C RPS16B ribosomal protein S16.e YDL090C RAM1 protein farnesyltransferase, beta subunit YDL092W SRP14 signal recognition particle subunit YDL095W PMT1 mannosyltransferase YDL097C RPN6 subunit of the regulatory particle of the proteasome YDL101C DUN1 protein kinase YDL102W CDC2 DNA-directed DNA polymerase delta, catalytic 125 KD subunit YDL106C PHO2 homeodomain protein YDL108W KIN28 cyclin-dependent ser/thr protein kinase YDL116W NUP84 nuclear pore protein YDL119C YDL119C similarity to bovine Graves disease carrier protein YDL120W YFH1 regulates mitochondrial iron accumulation YDL122W UBP1 ubiquitin-specific protease YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDL130W RPP1B 60S large subunit acidic ribosomal protein L44prime YDL130W-A STF1 ATPase stabilizing factor, 10 kDa YDL131W LYS21 homocitrate synthase YDL133C-A RPL41B ribosomal protein YDL135C RDI1 rho GDP dissociation inhibitor with activity toward RHO1P YDL136W RPL35B 60S large subunit ribosomal protein YDL137W ARF2 GTP-binding protein of the ARF family YDL140C RPO21 DNA-directed RNA polymerase II, 215 KD subunit YDL143W CCT4 component of chaperonin-containing T-complex YDL145C COP1 coatomer complex alpha chain of secretory pathway vesicles YDL147W RPN5 subunit of the regulatory particle of the proteasome YDL149W APG9 integral membrane protein required for Cvt and autophagy transport YDL150W RPC53 DNA-directed RNA polymerase III, 47 KD subunit YDL153C SAS10 involved in silencing YDL154W MSH5 meiosis-specific protein YDL160C DHH1 putative RNA helicase of the DEAD box family YDL161W ENT1 clathrin binding protein, required for endocytosis YDL164C CDC9 DNA ligase YDL165W CDC36 transcription factor YDL170W UGA3 transcriptional activator for GABA catabolic genes YDL174C DLD1 D-lactate ferricytochrome C oxidoreductase (D-LCR) YDL178W AIP2 actin interacting protein 2 YDL181W INH1 inhibitor of mitochondrial ATPase YDL182W LYS20 homocitrate synthase YDL184C RPL41A ribosomal protein YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL191W RPL35A 60S large subunit ribosomal protein YDL192W ARF1 small GTP-binding protein of the ARF family YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL195W SEC31 component of the COPII coat of ER-golgi vesicles YDL198C YHM1 member of the mitochondrial carrier family (MCF) YDL200C MGT1 O6-methylguanine DNA repair methyltransferase YDL202W MRPL11 ribosomal protein of the large subunit, mitochondrial YDL205C HEM3 porphobilinogen deaminase YDL207W GLE1 RNA export mediator YDL208W NHP2 nucleolar rRNA processing protein YDL210W UGA4 GABA-specific high-affinity permease YDL212W SHR3 endoplasmatic reticulum membrane protein YDL215C GDH2 NAD-specific glutamate dehydrogenase (NAD) YDL217C TIM22 subunit of the TIM22-complex YDL220C CDC13 cell division control protein YDL226C GCS1 ADP-ribosylation factor GTPase-activating protein (ARF-GAP) YDL227C HO homothallic switching endonuclease YDL229W SSB1 heat shock protein of HSP70 family YDL230W PTP1 protein tyrosine phosphatase YDL232W OST4 oligosaccharyltransferase subunit YDL236W PHO13 4-nitrophenylphosphatase YDL245C HXT15 strong similarity to HXT17P and HXT7P YDR001C NTH1 neutral trehalase (alpha,alpha-trehalase) YDR002W YRB1 ran-specific GTPase-activating protein YDR004W RAD57 DNA repair protein YDR006C SOK1 high copy suppressor of a cyclic AMP-dependent protein kinase mutant YDR007W TRP1 phosphoribosylanthranilate isomerase YDR011W SNQ2 multidrug resistance protein YDR012W RPL4B ribosomal protein L4.e.B YDR019C GCV1 glycine decarboxylase, subunit T YDR021W FAL1 involved in maturation of 18S rRNA YDR023W SES1 seryl-tRNA synthetase, cytosolic YDR025W RPS11A ribosomal protein S11.e YDR027C LUV1 interacts with the beta-tubulin binding protein RBL2P YDR028C REG1 regulatory subunit for protein phosphatase GLC7P YDR033W MRH1 membrane protein related to HSP30P YDR034C LYS14 transcriptional activator of lysine pathway genes YDR035W ARO3 2-dehydro-3-deoxyphosphoheptonate aldolase, phenylalanine-inhibited YDR037W KRS1 lysyl-tRNA synthetase, cytosolic YDR040C ENA1 P-type ATPase involved in Na+ and Li+ efflux YDR044W HEM13 coproporphyrinogen III oxidase YDR046C BAP3 valine transporter YDR047W HEM12 uroporphyrinogen decarboxylase YDR050C TPI1 triose-phosphate isomerase YDR052C DBF4 regulatory subunit for CDC7P protein kinase YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR057W YDR057W weak similarity to L.lactis mleR protein YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR064W RPS13 ribosomal protein YDR069C DOA4 ubiquitin-specific protease YDR073W SNF11 component of SWI/SNF transcription activator complex YDR074W TPS2 alpha,alpha-trehalose-phosphate synthase, 102 KD subunit YDR076W RAD55 DNA repair protein YDR077W SED1 abundant cell surface glycoprotein YDR079W PET100 cytochrome-c oxidase assembly protein YDR080W VPS41 required for the vacuolar assembly YDR081C PDC2 pyruvate decarboxylase regulatory protein YDR082W STN1 involved in telomere length regulation YDR085C AFR1 involved in morphogenesis of the mating projection YDR086C SSS1 ER protein-translocase complex subunit YDR088C SLU7 pre-mRNA splicing factor affecting 3' splice site choice YDR097C MSH6 DNA mismatch repair protein YDR106W ARP10 similarity to Actin proteins YDR107C YDR107C strong similarity to EMP70 protein YDR108W GSG1 sporulation specific protein YDR110W FOB1 DNA replication fork blocking protein YDR113C PDS1 cell cycle regulator YDR118W APC4 subunit of the anaphase promoting complex YDR120C TRM1 N2,N2-dimethylguanine tRNA methyltransferase YDR122W KIN1 ser/thr protein kinase YDR123C INO2 basic helix-loop-helix (BHLH) transcription factor YDR127W ARO1 arom pentafunctional enzyme YDR129C SAC6 actin filament bundling protein, fimbrin YDR134C YDR134C strong similarity to FLO1P, FLO5P, FLO9P and YLR110c YDR135C YCF1 glutathione S-conjugate transporter, vacuolar YDR138W HPR1 hyperrecombination protein related to TOP1P YDR142C PEX7 peroxisomal import protein - peroxin YDR144C MKC7 aspartyl protease of the periplasmic space YDR146C SWI5 transcription factor YDR148C KGD2 2-oxoglutarate dehydrogenase complex E2 component YDR155C CPH1 cyclophilin (peptidylprolyl isomerase) YDR156W RPA14 DNA-directed RNA polymerase I, A14 subunit YDR159W SAC3 leucine permease transcriptional regulator YDR164C SEC1 protein transport protein YDR166C SEC5 required for exocytosis YDR167W TAF25 TFIID and SAGA subunit YDR170C SEC7 component of non-clathrin vesicle coat YDR172W SUP35 eukaryotic peptide chain release factor GTP-binding subunit YDR173C ARG82 arginine metabolism transcription factor YDR174W HMO1 Non-histone protein YDR176W NGG1 general transcriptional adaptor or co-activator YDR177W UBC1 E2 ubiquitin-conjugating enzyme YDR178W SDH4 succinate dehydrogenase membrane anchor subunit for SDH2P YDR180W SCC2 involved in sister chromatid cohesion YDR182W CDC1 cell division control protein YDR188W CCT6 component of chaperonin-containing T-complex (zeta subunit) YDR189W SLY1 hydrophilic suppressor of YPT1 and member of the SEC1P family YDR190C RVB1 RUVB-like protein YDR192C NUP42 nuclear pore protein YDR194C MSS116 RNA helicase of the DEAD box family, mitochondrial YDR195W REF2 RNA 3'-end formation protein YDR197W CBS2 cytochrome B translational activator protein YDR201W SPC19 spindle pole body protein YDR207C UME6 negative transcriptional regulator YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR211W GCD6 translation initiation factor eIF2b epsilon, 81 kDa subunit YDR212W TCP1 component of chaperonin-containing T-complex YDR216W ADR1 zinc-finger transcription factor YDR217C RAD9 DNA repair checkpoint protein YDR218C SPR28 septin-related sporulation protein YDR224C HTB1 histone H2B YDR225W HTA1 histone H2A YDR226W ADK1 adenylate kinase, cytosolic YDR227W SIR4 silencing regulatory and DNA-repair protein YDR228C PCF11 component of pre-mRNA 3'-end processing factor CF I YDR231C COX20 in the maturation and assembly of cytochrome oxidase involved protein YDR232W HEM1 5-aminolevulinate synthase YDR233C YDR233C similarity to hypothetical protein YDL204w YDR234W LYS4 homoaconitase YDR235W PRP42 U1 snRNP associated protein, required for pre-mRNA splicing YDR237W MRPL7 ribosomal protein of the large subunit, mitochondrial YDR238C SEC26 coatomer complex beta chain of secretory pathway vesicles YDR240C SNU56 U1 snRNA protein, no counterpart in mammalian snRNP YDR243C PRP28 pre-mRNA splicing factor RNA helicase of DEAD box family YDR244W PEX5 peroxisomal targeting signal receptor YDR245W MNN10 subunit of mannosyltransferase complex YDR246W TRS23 TRAPP subunit of 20 kDa involved in targeting and fusion of ER to golgi transport vesicles YDR254W CHL4 chromosome segregation protein YDR256C CTA1 catalase A, peroxisomal YDR257C RMS1 regulatory protein YDR258C HSP78 heat shock protein of clpb family of ATP-dependent proteases, mitochondrial YDR259C YAP6 transcription factor, of a fungal-specific family of bzip proteins YDR261C EXG2 exo-beta-1,3-glucanase minor isoform YDR265W PEX10 peroxisomal assembly protein - peroxin YDR268W MSW1 tryptophanyl-tRNA synthetase, mitochondrial YDR270W CCC2 probable copper-transporting ATPase YDR272W GLO2 glyoxalase II (hydroxyacylglutathione hydrolase) YDR283C GCN2 ser/thr protein kinase YDR285W ZIP1 synaptonemal complex protein YDR292C SRP101 signal recognition particle receptor, alpha chain YDR293C SSD1 involved in the tolerance to high concentration of Ca2+ YDR297W SUR2 required for the hydroxylation of C-4 of the sphingoid moiety of ceramide YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR300C PRO1 glutamate 5-kinase YDR301W CFT1 pre-mRNA 3'-end processing factor CF II YDR303C RSC3 similarity to transcriptional regulator proteins YDR304C CYP5 peptidyl-prolyl cis-trans isomerase D precursor(cyclophilin D) of the ER YDR308C SRB7 DNA-directed RNA polymerase II holoenzyme and kornberg's mediator (SRB) subcomplex subunit YDR309C GIC2 CDC42 GTPase-binding protein YDR310C SUM1 suppressor of SIR mutations YDR311W TFB1 TFIIH subunit (transcription initiation factor), 75 kD YDR313C PIB1 phosphatidylinositol(3)-phosphate binding protein YDR318W MCM21 involved in minichromosome maintenance YDR321W ASP1 asparaginase YDR322C-A TIM11 subunit E of the dimeric form of mitochondrial F1F0-ATPase YDR322W MRPL35 ribosomal protein YmL35 of the large subunit, mitochondrial YDR323C PEP7 vacuolar segregation protein YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR329C PEX3 peroxisomal assembly protein - peroxin YDR331W GPI8 essential for GPI anchor attachment YDR337W MRPS28 ribosomal protein of the small subunit, mitochondrial YDR341C YDR341C arginyl-tRNA synthetase, cytosolic YDR342C HXT7 high-affinity hexose transporter YDR343C HXT6 high-affinity hexose transporter YDR345C HXT3 low-affinity hexose transporter YDR347W MRP1 ribosomal protein of the small subunit, mitochondrial YDR354W TRP4 anthranilate phosphoribosyltransferase YDR356W NUF1 spindle pole body component YDR358W GGA1 Arf-binding protein; involved in trafficking of proteins YDR362C TFC6 TFIIIC (transcription initiation factor) subunit, 91 kD YDR364C CDC40 cell division control protein YDR369C XRS2 DNA repair protein YDR372C YDR372C similarity to hypothetical S. pombe protein YDR375C BCS1 mitochondrial protein of the CDC48/PAS1/SEC18 (AAA) family of ATPases YDR376W ARH1 mitochondrial protein with similarity to human adrenodoxin reductase and ferredoxin-NADP+ reductase YDR377W ATP17 ATP synthase complex, subunit f YDR381W YRA1 RNA annealing protein YDR382W RPP2B 60S large subunit acidic ribosomal protein YDR385W EFT2 translation elongation factor eEF2 YDR388W RVS167 reduced viability upon starvation protein YDR389W SAC7 suppressor of actin mutation YDR390C UBA2 E1-like (ubiquitin-activating) enzyme YDR392W SPT3 general transcriptional adaptor or co-activator YDR394W RPT3 26S proteasome regulatory subunit YDR395W SXM1 putative beta-karyopherin YDR397C NCB2 functional homolog of human NC2beta/Dr1 YDR404C RPB7 DNA-directed RNA polymerase II, 19 KD subunit YDR405W MRP20 ribosomal protein of the large subunit, mitochondrial YDR407C TRS120 TRAPP subunit of 120 kDa involved in targeting and fusion of ER to golgi transport vesicles YDR408C ADE8 phosphoribosylglycinamide formyltransferase (GART) YDR410C STE14 farnesyl cysteine carboxyl-methyltransferase YDR414C ERD1 required for retention of luminal ER proteins YDR418W RPL12B 60S large subunit ribosomal protein L12.e YDR420W HKR1 Hansenula MrakII k9 killer toxin-resistance protein YDR423C CAD1 transcriptional activator YDR424C DYN2 dynein light chain 1, cytosolic YDR427W RPN9 subunit of the regulatory particle of the proteasome YDR429C TIF35 translation initiation factor eIF3 (p33 subunit) YDR432W NPL3 nucleolar protein YDR443C SSN2 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDR447C RPS17B ribosomal protein S17.e.B YDR448W ADA2 general transcriptional adaptor or co-activator YDR450W RPS18A ribosomal protein S18.e.c4 YDR456W NHX1 NA+-H+ antiporter YDR461W MFA1 mating pheromone a-factor 1 YDR462W MRPL28 ribosomal protein of the large subunit (YmL28), mitochondrial YDR463W STP1 pre-tRNA splicing protein, transcription factor YDR468C TLG1 member of the syntaxin family of t-SNAREs YDR471W RPL27B 60S large subunit ribosomal protein YDR472W TRS31 TRAPP subunit of 31 kDa involved in targeting and fusion of ER to golgi transport vesicles YDR473C PRP3 essential splicing factor YDR477W SNF1 carbon catabolite derepressing ser/thr protein kinase YDR480W DIG2 MAP kinase-associated protein, down-regulator of invasive growth and mating YDR481C PHO8 repressible alkaline phosphatase vacuolar YDR483W KRE2 alpha-1,2-mannosyltransferase YDR484W SAC2 suppressor of actin mutation YDR488C PAC11 required in the absence of CIN8P YDR495C VPS3 vacuolar sorting protein YDR497C ITR1 myo-inositol permease, major YDR498C SEC20 secretory pathway protein YDR500C RPL37B ribosomal protein L.37.e YDR513W TTR1 glutaredoxin YDR517W GRH1 Yeast (GR)ASP65 (H)omologue YDR518W EUG1 protein disulfide isomerase YDR519W FKB2 FK506/rapamycin-binding protein of the ER YDR529C QCR7 ubiquinol--cytochrome-c reductase subunit 7 YDR536W STL1 member of the sugar permease family YEL002C WBP1 oligosaccharyl transferase beta subunit precursor YEL003W GIM4 Gim complex component YEL004W YEA4 strong similarity to K.lactis golgi uridine diphosphate-N-acetylglucosamine transporter YEL009C GCN4 transcriptional activator of amino acid biosynthetic genes YEL011W GLC3 1,4-glucan branching enzyme (glycogen branching enzyme) YEL013W VAC8 required for vacuole inheritance and protein targeting from the cytoplasm to vacuole YEL017C-A PMP2 H+-ATPase subunit, plasma membrane YEL020W-A TIM9 essential subunit of the TIM22-complex for mitochondrial protein import YEL022W GEA2 GDP/GTP exchange factor for ARF YEL024W RIP1 ubiquinol--cytochrome-c reductase iron-sulfur protein precursor YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL032W MCM3 replication initiation protein YEL034W HYP2 translation initiation factor eIF5A.1 YEL036C ANP1 required for protein glycosylation in the golgi YEL037C RAD23 nucleotide excision repair protein (ubiquitin-like protein) YEL039C CYC7 cytochrome-c isoform 2 YEL042W GDA1 guanosine diphosphatase YEL047C FRDS1 soluble fumarate reductase, cytoplasmic YEL050C RML2 ribosomal L2 protein, mitochondrial YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YEL054C RPL12A 60S large subunit ribosomal protein L12.e YEL056W HAT2 subunit of the major yeast histone acetyltransferase YEL059C-A SOM1 required for mitochondrial IMP1 peptidase function YEL060C PRB1 protease B, vacuolar YEL061C CIN8 kinesin-related protein YEL063C CAN1 amino acid permease YEL069C HXT13 high-affinity hexose transporter YEL071W DLD3 D-lactate dehydrogenase YER001W MNN1 alpha-1,3-mannosyltransferase YER002W NOP16 weak similarity to chicken microfibril-associated protein YER003C PMI40 mannose-6-phosphate isomerase YER007W PAC2 involved in the stabilization of microtubles YER008C SEC3 component of exocyst complex YER009W NTF2 nuclear transport factor YER011W TIR1 cold-shock induced protein of the TIR1P,TIP1P family YER012W PRE1 20S proteasome subunit C11(beta4) YER013W PRP22 pre-mRNA splicing factor YER014W HEM14 protoporphyrinogen oxidase, mitochondrial YER015W FAA2 long-chain-fatty-acid--CoA ligase YER016W BIM1 binding to microtubules YER017C AFG3 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YER018C SPC25 spindle pole body protein YER021W RPN3 26S proteasome regulatory subunit YER022W SRB4 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YER023W PRO3 delta 1-pyrroline-5-carboxylate reductase YER025W GCD11 translation initiation factor eIF2 gamma chain YER026C CHO1 CDP-diacylglycerol serine O-phosphatidyltransferase YER029C SMB1 associated with U1 snRNP as part of the Sm-core that is common to all spliceosomal snRNPs YER031C YPT31 GTP-binding protein of the rab family YER040W GLN3 transcription factor for positive nitrogen regulation YER047C SAP1 member of the AAA-protein family YER056C FCY2 purine-cytosine permease YER056C-A RPL34A ribosomal protein L34 YER058W PET117 cytochrome c oxidase assembly factor YER061C CEM1 beta-keto-acyl-ACP synthase, mitochondrial YER065C ICL1 isocitrate lyase YER068W MOT2 transcriptional repressor YER069W ARG5,6 acetylglutamate kinase and acetylglutamyl-phosphate reductase YER072W VTC1 Negative Regulator of Cdc Fourty two (CDC42) YER073W ALD5 aldehyde dehydrogenase (NAD+), mitochondrial YER074W RPS24A 40s small subunit ribosomal protein S24.e YER086W ILV1 anabolic serine and threonine dehydratase precursor YER087C-B SBH1 involved in translocation into the ER YER088C DOT6 involved in derepression of telomeric silencing YER090W TRP2 anthranilate synthase component I YER091C MET6 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase YER094C PUP3 20S proteasome subunit (beta3) YER095W RAD51 DNA repair protein YER100W UBC6 E2 ubiquitin-conjugating enzyme YER102W RPS8B ribosomal protein S8.e YER103W SSA4 heat shock protein of HSP70 family, cytosolic YER105C NUP157 nuclear pore protein YER107C GLE2 required for nuclear pore complex structure and function YER109C FLO8 required for diploid filamentous growth YER110C KAP123 RAN-binding protein YER111C SWI4 transcription factor YER112W LSM4 Sm-like (Lsm) protein YER117W RPL23B ribosomal protein L23.e YER118C SHO1 involved in the HOG1 high-osmolarity signal transduction pathway YER120W SCS2 required for inositol metabolism YER122C GLO3 zinc finger protein YER123W YCK3 casein kinase, isoform 3 YER125W RSP5 hect domain E3 ubiquitin-protein ligase YER131W RPS26B 40S small subunit ribosomal protein S26e-c5 YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER136W GDI1 GDP dissociation inhibitor YER141W COX15 cytochrome oxidase assembly factor YER142C MAG1 3-methyladenine DNA glycosylase YER145C FTR1 iron permease that mediates high-affinity iron uptake YER146W LSM5 Sm-like (Lsm) protein YER148W SPT15 the TATA-binding protein TBP YER151C UBP3 ubiquitin-specific proteinase YER153C PET122 translational activator of cytochrome c oxidase subunit III YER154W OXA1 cytochrome oxidase biogenesis protein YER155C BEM2 GTPase-activating protein YER157W SEC34 required for vesicle tethering to the yeast Golgi apparatus YER159C BUR6 functional homolog of human NC2alpha YER161C SPT2 multifunctional HMG-like chromatin protein YER162C RAD4 excision repair protein YER165W PAB1 mRNA polyadenylate-binding protein YER168C CCA1 tRNA nucleotidyltransferase YER170W ADK2 adenylate kinase, mitochondrial YER171W RAD3 DNA helicase/ATPase YER172C BRR2 RNA helicase-related protein YER176W ECM32 DNA dependent ATPase/DNA helicase B YER178W PDA1 pyruvate dehydrogenase (lipoamide) alpha chain precursor YER179W DMC1 meiosis-specific protein YER184C YER184C similarity to multidrug resistance proteins PDR3P and PDR1P YFL001W DEG1 pseudouridine synthase YFL002C SPB4 ATP-dependent RNA helicase of DEAH box family YFL003C MSH4 meiosis-specific protein YFL005W SEC4 GTP-binding protein of the ras superfamily YFL008W SMC1 chromosome segregation protein YFL009W CDC4 cell division control protein YFL011W HXT10 hexose transporter YFL016C MDJ1 heat shock protein - chaperone YFL017C GNA1 essential acetyltransferase YFL017W-A SMX2 snRNP G protein (the homologue of the human Sm-G) YFL018C LPD1 dihydrolipoamide dehydrogenase precursor YFL021W GAT1 transcription factor for nitrogen regulation YFL022C FRS2 phenylalanine--tRNA ligase beta chain, cytosolic YFL025C BST1 negative regulator of COPII vesicle formation YFL026W STE2 pheromone alpha-factor receptor YFL031W HAC1 transcription factor YFL036W RPO41 DNA-directed RNA polymerase, mitochondrial YFL037W TUB2 beta-tubulin YFL038C YPT1 GTP-binding protein of the rab family YFL039C ACT1 actin YFL041W FET5 multicopy oxidase YFL045C SEC53 phosphomannomutase YFL048C EMP47 Golgi membrane protein YFL050C ALR2 divalent cation transprter YFL051C YFL051C strong similarity to FLO1P, FLO5P and FLO9P - putative pseudogene YFR002W NIC96 nuclear pore protein YFR004W RPN11 26S proteasome regulatory subunit YFR009W GCN20 positive effector of GCN2P YFR013W IOC3 similarity to YOL017w YFR014C CMK1 Ca2+/calmodulin-dependent ser/thr protein kinase type I YFR015C GSY1 UDP glucose--starch glucosyltransferase, isoform 1 YFR023W PES4 DNA-directed DNA polymerase epsilon suppressor YFR024C-A LSB3 possible role in the regulation of actin cytoskeletal organization YFR031C SMC2 chromosome segregation protein YFR032C-A RPL29 60S large subunit ribosomal protein YFR033C QCR6 ubiquinol--cytochrome-c reductase 17K protein YFR034C PHO4 transcription factor YFR036W CDC26 subunit of anaphase-promoting complex (cyclosome) YFR037C RSC8 subunit of the RSC complex YFR049W YMR31 ribosomal protein, mitochondrial YFR050C PRE4 20S proteasome subunit(beta7) YFR051C RET2 coatomer complex delta chain YFR052W RPN12 26S proteasome regulatory subunit YFR053C HXK1 hexokinase I YGL006W PMC1 Ca2+-transporting P-type ATPase YGL008C PMA1 H+-transporting P-type ATPase, major isoform, plasma membrane YGL009C LEU1 3-isopropylmalate dehydratase YGL011C SCL1 20S proteasome subunit YC7ALPHA/Y8 (alpha1) YGL013C PDR1 transcription factor YGL016W KAP122 Member of the karyopherin-beta family, nuclear import YGL017W ATE1 arginyl tRNA transferase YGL018C JAC1 molecular chaperone YGL019W CKB1 casein kinase II, beta subunit YGL022W STT3 oligosaccharyl transferase subunit YGL025C PGD1 mediator complex subunit YGL026C TRP5 tryptophan synthase YGL027C CWH41 ER glucosidase I YGL030W RPL30 60S large subunit ribosomal protein L30.e YGL031C RPL24A 60S large subunit ribosomal protein L24.e.A YGL032C AGA2 a-agglutinin binding subunit YGL033W HOP2 required for pairing of homologous chromosomes YGL035C MIG1 transcriptional repressor YGL038C OCH1 alpha-1,6-mannosyltransferase YGL040C HEM2 porphobilinogen synthase YGL043W DST1 TFIIS (transcription elongation factor) YGL044C RNA15 component of pre-mRNA 3'-end processing factor CF I YGL048C RPT6 26S proteasome regulatory subunit YGL049C TIF4632 mRNA cap-binding protein (eIF4F), 130K subunit YGL054C ERV14 ER-derived Vesicles YGL055W OLE1 stearoyl-CoA desaturase YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL061C DUO1 essential mitotic spindle protein YGL062W PYC1 pyruvate carboxylase 1 YGL068W YGL068W strong similarity to Cricetus mitochrondial ribosomal L12 protein YGL070C RPB9 DNA-directed RNA polymerase II, 14.2 KD subunit YGL071W RCS1 iron-regulated transcriptional repressor YGL073W HSF1 heat shock transcription factor YGL075C MPS2 Protein of the nuclear envelope/endoplasmic reticulum required for spindle pole body assembly and normal chromosome segregation YGL076C RPL7A 60S large subunit ribosomal protein L7.e.A YGL077C HNM1 choline permease YGL078C DBP3 putative RNA helicase required for pre-rRNA processing YGL086W MAD1 spindle assembly checkpoint protein YGL089C MF(ALPHA)2 mating pheromone alpha-2 factor YGL090W LIF1 DNA ligase IV interacting factor YGL091C NBP35 nucleotide-binding protein YGL092W NUP145 nuclear pore protein YGL093W SPC105 spindle pole body protein YGL095C VPS45 vacuolar protein sorting-associated protein YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL100W SEH1 nuclear pore protein YGL103W RPL28 60S large subunit ribosomal protein L27a.e YGL105W ARC1 protein with specific affinity for G4 quadruplex nucleic acids YGL112C TAF60 TFIID and SAGA subunit YGL115W SNF4 nuclear regulatory protein YGL116W CDC20 cell division control protein YGL119W ABC1 ubiquinol--cytochrome-c reductase complex assembly protein YGL120C PRP43 involved in spliceosome disassembly YGL122C NAB2 nuclear poly(A)-binding protein YGL123W RPS2 40S small subunit ribosomal protein YGL125W MET13 putative methylene tetrahydrofolate reductase YGL130W CEG1 mRNA guanylyltransferase (mRNA capping enzyme, alpha subunit) YGL131C YGL131C weak similarity to S.pombe hypothetical protein C3H1.12C YGL133W ITC1 subunit of ISW2 chromatin remodelling complex YGL135W RPL1B 60S large subunit ribosomal protein YGL137W SEC27 coatomer complex beta' chain (beta'-cop) of secretory pathway vesicles YGL143C MRF1 peptide chain release factor, mitochondrial YGL145W TIP20 required for ER to Golgi transport YGL147C RPL9A ribosomal protein L9.e YGL148W ARO2 chorismate synthase YGL151W NUT1 negative transcription regulator from artifical reporters YGL153W PEX14 peroxisomal protein involved in protein import - peroxin YGL154C LYS5 L-aminoadipate-semialdehyde dehydrogenase, small subunit YGL155W CDC43 geranylgeranyltransferase beta subunit YGL156W AMS1 alpha-mannosidase YGL163C RAD54 DNA-dependent ATPase of the SNF2P family YGL166W CUP2 copper-dependent transcription factor YGL167C PMR1 Ca2+-transporting P-type ATPase YGL172W NUP49 nuclear pore protein YGL173C KEM1 multifunctional nuclease YGL180W APG1 essential for autophagocytosis YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL187C COX4 cytochrome-c oxidase chain IV YGL189C RPS26A 40S small subunit ribosomal protein S26e.c7 YGL191W COX13 cytochrome-c oxidase chain VIa YGL192W IME4 positive transcription factor for IME2 YGL195W GCN1 translational activator YGL200C EMP24 component of the COPII-coated vesicles, 24 kDa YGL201C MCM6 involved in replication YGL203C KEX1 carboxypeptidase (YSC-alpha) YGL205W POX1 acyl-CoA oxidase YGL206C CHC1 clathrin heavy chain YGL207W SPT16 general chromatin factor YGL208W SIP2 dominant suppressor of some ts mutations in RPO21 and PRP4 YGL212W VAM7 vacuolar morphogenesis protein YGL216W KIP3 kinesin-related protein required for nuclear migration YGL225W GOG5 GDP-mannose transporter into the lumen of the Golgi YGL226C-A OST5 subunit of N-oligosaccharyltransferase, zeta subunit YGL233W SEC15 vesicular traffic control protein YGL236C MTO1 strong similarity to gidA E.coli protein YGL237C HAP2 CCAAT-binding factor subunit YGL238W CSE1 importin-beta-like protein YGL241W KAP114 Member of the karyopherin-beta family, nuclear import YGL244W RTF1 regulates DNA binding properties of TBP YGL248W PDE1 low affinity 3',5'-cyclic-nucleotide phosphodiesterase YGL251C HFM1 DNA/RNA helicase YGL252C RTG2 retrograde regulation protein YGL253W HXK2 hexokinase II YGL254W FZF1 sulfite resistance protein YGL256W ADH4 alcohol dehydrogenase IV YGR005C TFG2 TFIIF subunit (transcription initiation factor), 54 kD YGR006W PRP18 U5 snRNA-associated protein YGR008C STF2 ATPase stabilizing factor YGR009C SEC9 protein transport protein YGR013W SNU71 associated with U1 snRNP, no counterpart in mammalian U1 snRNP YGR014W MSB2 multicopy suppressor of a CDC24 bud emergence defect YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YGR027C RPS25A ribosomal protein S25.e.c7 YGR028W MSP1 intra-mitochondrial sorting protein YGR029W ERV1 mitochondrial biogenesis and regulation of cell cycle YGR030C POP6 required for processing of tRNAs and rRNAs YGR032W GSC2 1,3-beta-D-glucan synthase subunit YGR034W RPL26B 60S large subunit ribosomal protein YGR040W KSS1 ser/thr protein kinase of the MAP kinase family YGR044C RME1 zinc-finger transcription factor YGR047C TFC4 TFIIIC (transcription initiation factor) subunit, 131 kD YGR055W MUP1 high affinity methionine permease YGR056W RSC1 member of RSC complex, which remodels the structure of chromatin YGR059W SPR3 sporulation-specific septin YGR060W ERG25 C-4 sterol methyl oxidase YGR061C ADE6 5'-phosphoribosylformyl glycinamidine synthetase YGR062C COX18 required for activity of mitochondrial cytochrome oxidase YGR063C SPT4 transcription elongation protein YGR072W UPF3 nonsense-mediated mRNA decay protein YGR074W SMD1 snRNA-associated protein YGR075C PRP38 pre-mRNA splicing factor YGR076C MRPL25 ribosomal protein YmL25, mitochondrial YGR077C PEX8 similarity to Hansenula polymorpha PER1 protein and weak similarity to Pichia pastoris PER3 protein YGR078C PAC10 GIM4 - Gim complex component YGR080W TWF1 twinfilin, an actin monomer sequestering protein YGR082W TOM20 mitochondrial outer membrane import receptor subunit, 20 kD YGR083C GCD2 translation initiation factor eIF2B, 71 kDa (delta) subunit YGR084C MRP13 ribosomal protein of the small subunit, mitochondrial YGR085C RPL11B ribosomal protein YGR087C PDC6 pyruvate decarboxylase 3 YGR088W CTT1 catalase T, cytosolic YGR091W PRP31 pre-mRNA splicing protein YGR094W VAS1 valyl-tRNA synthetase YGR098C ESP1 required for sister chromatid separation YGR099W TEL2 involved in controlling telomere length and position effect YGR104C SRB5 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YGR105W VMA21 ATPase assembly integral membrane protein YGR112W SHY1 SURF homologue protein YGR113W DAM1 essential mitotic spindle pole protein YGR116W SPT6 transcription elongation protein YGR118W RPS23A 40S small subunit ribosomal protein S23.e YGR119C NUP57 nuclear pore protein YGR120C SEC35 required for ER to golgi vesicle docking YGR121C MEP1 ammonia permease of high capacity and moderate affinity YGR133W PEX4 E2 ubiquitin-conjugating enzyme - peroxin YGR135W PRE9 20S proteasome subunit Y13 (alpha3) YGR136W LSB1 weak similarity to chicken growth factor receptor-binding protein GRB2 homolog YGR140W CBF2 kinetochore protein complex CBF3, 110 KD subunit YGR143W SKN1 glucan synthase subunit YGR147C NAT2 N-acetyltransferase for N-terminal methionine YGR148C RPL24B 60S large subunit ribosomal protein L24.e.B YGR152C RSR1 GTP-binding protein YGR157W CHO2 phosphatidylethanolamine N-methyltransferase YGR158C MTR3 involved in mRNA transport YGR159C NSR1 nuclear localization sequence binding protein YGR162W TIF4631 mRNA cap-binding protein (eIF4F), 150K subunit YGR166W KRE11 beta-glucan synthesis-associated protein YGR167W CLC1 clathrin light chain YGR170W PSD2 phosphatidylserine decarboxylase 2 YGR171C MSM1 methionyl-tRNA synthetase YGR172C YIP1 golgi membrane protein YGR174C CBP4 ubiquinol--cytochrome-c reductase assembly factor YGR175C ERG1 squalene monooxygenase YGR178C PBP1 PAB1P interacting protein YGR180C RNR4 ribonucleotide reductase small subunit YGR183C QCR9 ubiquinol--cytochrome-c reductase subunit 9 YGR184C UBR1 ubiquitin-protein ligase YGR185C TYS1 tyrosyl-tRNA synthetase YGR186W TFG1 TFIIF subunit (transcription initiation factor), 105 kD YGR188C BUB1 ser/thr protein kinase YGR189C CRH1 family of putative glycosidases might exert a common role in cell wall organization YGR191W HIP1 histidine permease YGR192C TDH3 glyceraldehyde-3-phosphate dehydrogenase 3 YGR193C PDX1 pyruvate dehydrogenase complex protein X YGR202C PCT1 cholinephosphate cytidylyltransferase YGR204W ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YGR207C ETF-BETA electron-transferring flavoprotein, beta chain YGR214W RPS0A 40S ribosomal protein p40 homolog A YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YGR218W CRM1 nuclear export factor, exportin YGR220C MRPL9 ribosomal protein YmL9, mitochondrial YGR222W PET54 splicing protein and translational activator, mitochondrial YGR229C SMI1 beta-1,3-glucan synthesis protein YGR232W NAS6 possible homolog of human 26S proteasome regulatory subunit p28 YGR234W YHB1 flavohemoglobin YGR238C KEL2 involved in cell fusion and morphogenesis YGR240C PFK1 6-phosphofructokinase, alpha subunit YGR241C YAP1802 Yeast Adaptor Protein, member of AP180 protein family YGR245C SDA1 required for normal organization of the actin cytoskeleton; required for passage through Start YGR246C BRF1 TFIIIB subunit, 70 kD YGR252W GCN5 histone acetyltransferase YGR253C PUP2 20S proteasome subunit(alpha5) YGR254W ENO1 enolase I (2-phosphoglycerate dehydratase) YGR258C RAD2 structure-specific nuclease of the nucleotide excision repairosome YGR261C APL6 AP-3 complex subunit, beta3-adaptin, 91 KD YGR264C MES1 methionyl-tRNA synthetase YGR270W YTA7 26S proteasome subunit YGR274C TAF145 TFIID subunit (TBP-associated factor), 145 kD YGR281W YOR1 ATP-binding cassette transporter protein YGR282C BGL2 endo-beta-1,3-glucanase of the cell wall YGR285C ZUO1 zuotin, a putative Z-DNA binding protein YGR288W MAL13 maltose pathway regulatory protein YGR292W MAL12 alpha-glucosidase of the MAL1 locus YHL001W RPL14B ribosomal protein YHL004W MRP4 ribosomal protein of the small subunit, mitochondrial YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHL009C YAP3 transcription factor, of a fungal-specific family of bzip proteins YHL015W RPS20 ribosomal protein YHL016C DUR3 urea transport protein YHL019C APM2 involved in clathrin-independent transport processes YHL020C OPI1 negative regulator of phospholipid biosynthesis pathway YHL022C SPO11 catalytic subunit of the meiotic double strand break transesterase YHL025W SNF6 global transcription activator YHL027W RIM101 meiotic regulatory protein YHL031C GOS1 SNARE protein of Golgi compartment YHL033C RPL8A 60S large subunit ribosomal protein L7a.e.A YHL034C SBP1 single-strand nucleic acid binding protein YHL036W MUP3 very low affinity methionine permease YHL038C CBP2 apo-cytochrome b pre-mRNA processing protein 2 YHR001W-A QCR10 ubiquinol--cytochrome-c reductase 8.5 kDa subunit YHR004C NEM1 required for nuclear morphology YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR005C-A MRS11 subunit of the TIM22-complex YHR007C ERG11 cytochrome P450 lanosterol 14a-demethylase YHR008C SOD2 superoxide dismutase (Mn) precursor, mitochondrial YHR010W RPL27A 60S large subunit ribosomal protein L27.e YHR012W VPS29 involved in vacuolar protein sorting YHR013C ARD1 protein N-acetyltransferase subunit YHR016C YSC84 strong similarity to hypothetical protein YFR024c-a YHR018C ARG4 arginosuccinate lyase YHR021C RPS27B ribosomal protein S27.e YHR023W MYO1 myosin-1 isoform (type II myosin) heavy chain YHR024C MAS2 processing peptidase, catalytic 53kDa (alpha) subunit, mitochondrial YHR026W PPA1 H+-ATPase 23 KD subunit, vacuolar YHR027C RPN1 26S proteasome regulatory subunit YHR028C DAP2 dipeptidyl aminopeptidase B YHR037W PUT2 1-pyrroline-5-carboxylate dehydrogenase YHR038W FIL1 Killed in Mutagen, sensitive to Diepoxybutane and/or Mitomycin C YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YHR041C SRB2 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YHR042W NCP1 NADPH-cytochrome P450 reductase YHR050W SMF2 probable manganese transporter YHR051W COX6 cytochrome-c oxidase subunit VI YHR053C CUP1-1 metallothionein YHR055C CUP1-2 metallothionein YHR057C CYP2 peptidyl-prolyl cis-trans isomerase YHR058C MED6 RNA polymerase II transcriptional regulation mediator YHR060W VMA22 vacuolar ATPase assembly protein YHR062C RPP1 required for processing of tRNA and 35S rRNA YHR065C RRP3 required for maturation of the 35S primary transcript YHR066W SSF1 mating protein YHR069C RRP4 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YHR072W ERG7 lanosterol synthase YHR072W-A NOP10 nucleolar rRNA processing protein YHR075C PPE1 ribosomal protein of the small subunit, mitochondrial YHR076W YHR076W weak similarity to C.elegans hypothetical protein CEW09D10 YHR077C NMD2 nonsense-mediated mRNA decay protein 2 YHR079C IRE1 protein kinase YHR082C KSP1 ser/thr protein kinase YHR084W STE12 transcriptional activator YHR089C GAR1 nucleolar rRNA processing protein YHR090C YNG2 component of NuA4 histone acetyltransferase complex YHR091C MSR1 arginyl-tRNA synthetase, mitochondrial YHR092C HXT4 moderate- to low-affinity glucose transporter YHR094C HXT1 low-affinity hexose transporter YHR096C HXT5 member of the hexose transporter family YHR107C CDC12 septin YHR117W TOM71 protein with similarity to TOM70P/Mas70p YHR118C ORC6 origin recognition complex, 50 KD subunit YHR119W SET1 involved in chromatin-mediated gene regulation YHR120W MSH1 DNA mismatch repair protein, mitochondrial YHR123W EPT1 sn-1,2-diacylglycerol ethanolamine- and cholinephosphotransferase YHR128W FUR1 uracil phosphoribosyltransferase YHR129C ARP1 centractin YHR135C YCK1 casein kinase I isoform YHR139C SPS100 sporulation-specific wall maturation protein YHR141C RPL42B ribosomal protein L36a.e YHR142W CHS7 control of protein export from the ER (like chitin synthase III) YHR143W-A RPC10 DNA-directed RNA polymerases I, II, III 7.7 KD subunit YHR147C MRPL6 ribosomal protein of the large subunit, mitochondrial YHR157W REC104 meiosis-specific protein YHR158C KEL1 involved in cell fusion and morphology YHR161C YAP1801 Yeast Adaptor Protein, member of AP180 protein family YHR164C DNA2 DNA helicase YHR165C PRP8 U5 snRNP protein, pre-mRNA splicing factor YHR166C CDC23 subunit of anaphase-promoting complex (cyclosome) YHR171W APG7 component of the autophagic system YHR172W SPC97 spindle pole body component YHR174W ENO2 enolase II (2-phosphoglycerate dehydratase) YHR183W GND1 6-phosphogluconate dehydrogenase YHR184W SSP1 essential for meiosis and spore formation YHR190W ERG9 farnesyl-diphosphate farnesyltransferase YHR193C EGD2 alpha subunit of the nascent polypeptide-associated complex YHR195W NVJ1 part of nucleus-vacuole junctions YHR200W RPN10 26S proteasome regulatory subunit YHR201C PPX1 exopolyphosphatase YHR203C RPS4B ribosomal protein S4.e.c8 YHR206W SKN7 transcription factor with similarity to HSF1P YHR208W BAT1 branched chain amino acid aminotransferase, mitochondrial YHR210C YHR210C strong similarity to UDP-glucose-4-epimerase YHR215W PHO12 secreted acid phosphatase YIL004C BET1 protein transport protein YIL013C PDR11 membrane transporter YIL015W BAR1 barrierpepsin precursor YIL018W RPL2B 60S large subunit ribosomal protein L8.e YIL021W RPB3 DNA-directed RNA-polymerase II, 45 kDa YIL022W TIM44 mitochondrial inner membrane import receptor subunit YIL026C IRR1 essential protein YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL034C CAP2 F-actin capping protein, beta subunit YIL035C CKA1 casein kinase II, catalytic alpha chain YIL038C NOT3 general negative regulator of transcription, subunit 3 YIL043C CBR1 cytochrome-b5 reductase YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL047C SYG1 member of the major facilitator superfamily YIL052C RPL34B ribosomal protein L34.e YIL061C SNP1 U1 small nuclear ribonucleoprotein YIL062C ARC15 subunit of the ARP2/3 complex YIL063C YRB2 involved in nuclear protein export YIL066C RNR3 ribonucleotide reductase, repair inducible large subunit YIL068C SEC6 protein transport protein YIL069C RPS24B 40S small subunit ribosomal protein S24.e YIL070C MAM33 mitochondrial acidic matrix protein YIL072W HOP1 meiosis-specific protein YIL075C RPN2 26S proteasome regulatory subunit YIL076W SEC28 epsilon-COP coatomer subunit YIL078W THS1 threonyl tRNA synthetase, cytosolic YIL084C SDS3 transcriptional regulator YIL095W PRK1 serine/threonine protein kinase involved in regulation of actin cytoskeleton organization YIL099W SGA1 sporulation specific glucan 1,4-alpha-glucosidase YIL107C PFK26 6-phosphofructose-2-kinase, isozyme 1 YIL109C SEC24 component of COPII coat of ER-Golgi vesicles YIL111W COX5B cytochrome-c oxidase chain Vb YIL114C POR2 voltage dependent anion channel (YVDAC2) YIL115C NUP159 nuclear pore protein YIL125W KGD1 2-oxoglutarate dehydrogenase complex E1 component YIL126W STH1 subunit of the RSC complex YIL128W MET18 involved in NER repair and RNA polymerase II transcription YIL129C TAO3 Transcriptional Activator of OCH1 YIL131C FKH1 forkhead protein, involved in transcriptional silencing, cell morphology and cell cycle YIL133C RPL16A 60S large subunit ribosomal protein YIL134W FLX1 FAD carrier protein (MCF), mitochondrial YIL136W OM45 protein of the outer mitochondrial membrane YIL138C TPM2 tropomyosin, isoform 2 YIL140W AXL2 required for axial pattern of budding YIL142W CCT2 chaperonin of the TCP1 ring complex, cytosolic YIL143C SSL2 DNA helicase YIL144W TID3 DMC1P interacting protein YIL147C SLN1 two-component signal transducer YIL148W RPL40A ubiquitin YIL149C MLP2 involved in translocation of macromolecules between the nucleoplasm and the NPC YIL150C DNA43 required for S-phase initiation or completion YIL155C GUT2 glycerol-3-phosphate dehydrogenase, mitochondrial YIL159W BNR1 regulator of budding YIL160C POT1 acetyl-CoA C-acyltransferase, peroxisomal YIL162W SUC2 invertase (sucrose hydrolyzing enzyme) YIL167W SDL1 serine dehydratase YIL170W HXT12 strong similarity to sugar transport proteins YIR004W DJP1 DnaJ-like protein involved specifically in peroxisomal protein import YIR006C PAN1 actin-cytoskeleton assembly protein YIR008C PRI1 DNA-directed DNA polymerase alpha 48kDa subunit (DNA primase) YIR011C STS1 required for transport of RNA15P from the cytoplasm to the nucleus YIR012W SQT1 suppresses dominant-negative mutants of the ribosomal protein QSR1 YIR015W RPR2 RNase P subunit YIR017C MET28 transcriptional activator of sulfur amino acid metabolism YIR018W YAP5 involved in transcription activation YIR019C MUC1 extracellular alpha-1,4-glucan glucosidase YIR021W MRS1 involved in mitochondrial RNA splicing of COB mRNA YIR022W SEC11 signal sequence processing protein YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YIR028W DAL4 allantoin permease YIR031C DAL7 malate synthase 2 YIR033W MGA2 may be involved in the remodeling chromatin structure YIR034C LYS1 saccharopine dehydrogenase YJL001W PRE3 20S proteasome subunit (beta1) YJL002C OST1 oligosaccharyltransferase, alpha subunit YJL005W CYR1 adenylate cyclase YJL006C CTK2 carboxy-terminal domain (CTD) kinase, beta subunit YJL008C CCT8 component of chaperonin-containing T-complex YJL013C MAD3 spindle-assembly checkpoint protein YJL014W CCT3 chaperonin of the TCP1 ring complex, cytosolic YJL023C PET130 protein synthesis protein, mitochondrial YJL025W RRN7 polymerase I specific transcription initiation factor YJL026W RNR2 ribonucleoside-diphosphate reductase, small subunit YJL029C VPS53 subunit of VP52-54 complex, required for protein sorting at the yeast late Golgi YJL031C BET4 geranylgeranyl transferase, alpha chain YJL034W KAR2 nuclear fusion protein YJL039C NUP192 nucleoporin localize at the inner site of the nuclear membrane YJL041W NSP1 nuclear pore protein YJL042W MHP1 microtubule-associated protein YJL050W MTR4 involved in nucleocytoplasmic transport of mRNA YJL052W TDH1 glyceraldehyde-3-phosphate dehydrogenase 1 YJL053W PEP8 vacuolar protein sorting/targeting protein YJL054W TIM54 translocase for the insertion of proteins into the mitochondrial inner membrane YJL056C ZAP1 metalloregulatory protein involved in zinc-responsive transcriptional regulation YJL061W NUP82 nuclear pore protein YJL062W LAS21 required for addition of a side chain to the glycosylphospatidylinositol (GPI) core structure YJL063C MRPL8 ribosomal protein L17, mitochondrial YJL073W JEM1 similarity to heat shock proteins YJL080C SCP160 required for maintenance of exact ploidy YJL081C ARP4 actin-related protein YJL085W EXO70 70 kDa exocyst component protein YJL087C TRL1 tRNA ligase YJL088W ARG3 ornithine carbamoyltransferase YJL089W SIP4 interacts with SNF1 protein kinase YJL090C DPB11 involved in DNA replication and S-phase checkpoint YJL092W HPR5 ATP-dependent DNA helicase YJL093C TOK1 outward-rectifier potassium channel YJL095W BCK1 ser/thr protein kinase of the MEKK family YJL096W MRPL49 ribosomal protein YmL49, mitochondrial YJL102W MEF2 translation elongation factor, mitochondrial YJL103C YJL103C similarity to YBR239c YJL110C GZF3 transcriptional repressor YJL111W CCT7 component of chaperonin-containing T-complex YJL121C RPE1 D-ribulose-5-phosphate 3-epimerase YJL127C SPT10 transcription regulatory protein YJL129C TRK1 potassium transport protein TRK1P, high-affinity YJL130C URA2 multifunctional pyrimidine biosynthesis protein YJL133W MRS3 RNA splicing protein and member of the mitochondrial carrier family (MCF) YJL136C RPS21B 40S small subunit ribosomal protein S21.e YJL138C TIF2 translation initiation factor eIF4A YJL139C YUR1 mannosyltransferase YJL140W RPB4 DNA-directed RNA polymerase II, 32 kDa subunit YJL141C YAK1 ser/thr protein kinase YJL143W TIM17 mitochondrial inner membrane import translocase subunit YJL148W RPA34 nonessential component of RNA-polI YJL153C INO1 myo-inositol-1-phosphate synthase YJL154C VPS35 protein-sorting protein, vacuolar YJL155C FBP26 fructose-2,6-bisphosphatase YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJL159W HSP150 member of the PIR1P/HSP150P/PIR3P family YJL164C TPK1 cAMP-dependent protein kinase 1, catalytic chain YJL166W QCR8 ubiquinol--cytochrome-c reductase chain VIII YJL167W ERG20 farnesyl-pyrophosphate synthetase YJL172W CPS1 Gly-X carboxypeptidase YSCS precursor YJL173C RFA3 DNA replication factor A, 13 KD subunit YJL174W KRE9 cell wall synthesis protein YJL176C SWI3 transcription regulatory protein YJL177W RPL17B 60s large subunit ribosomal protein L17.e YJL180C ATP12 F1F0-ATPase complex assembly protein YJL189W RPL39 60S large subunit ribosomal protein L39.e YJL190C RPS22A ribosomal protein S15a.e.c10 YJL191W RPS14B 40S small subunit ribosomal protein S14.e.B YJL194W CDC6 cell division control protein YJL203W PRP21 pre-mRNA splicing factor YJL208C NUC1 nuclease, mitochondrial YJL209W CBP1 apo-cytochrome b pre-mRNA processing protein YJL210W PEX2 peroxisomal assembly protein - peroxin YJL214W HXT8 hexose transport protein YJL219W HXT9 hexose transport protein YJR002W MPP10 component of the U3 small nucleolar ribonucleoprotein YJR004C SAG1 alpha-agglutinin YJR005W APL1 AP-2 complex subunit, beta2-adaptin, 78 KD YJR006W HYS2 DNA-directed DNA polymerase delta, 55 KD subunit YJR007W SUI2 translation initiation factor eIF2, alpha chain YJR009C TDH2 glyceraldehyde-3-phosphate dehydrogenase 2 YJR010C-A SPC1 signal peptidase 10.8 kDa subunit YJR016C ILV3 dihydroxy-acid dehydratase YJR019C TES1 thioesterase, peroxisomal YJR021C REC107 meiotic recombination protein YJR022W LSM8 splicing factor YJR023C YJR023C hypothetical protein YJR031C GEA1 GDP/GTP exchange factor for ARF YJR034W PET191 involved in assembly of cytochrome oxidase YJR035W RAD26 DNA repair and recombination protein YJR040W GEF1 voltage-gated chloride channel protein YJR042W NUP85 nuclear pore protein YJR043C POL32 polymerase-associated gene, third (55 kDa) subunit of DNA polymerase delta YJR045C SSC1 mitochondrial heat shock protein 70-related protein YJR047C ANB1 translation initiation factor eIF5A.2 YJR048W CYC1 cytochrome-c isoform 1 YJR051W OSM1 osmotic growth protein YJR052W RAD7 nucleotide excision repair protein YJR057W CDC8 dTMP kinase YJR058C APS2 AP-2 complex subunit, sigma2 subunit, 17 KD YJR060W CBF1 kinetochore protein YJR062C NTA1 amino-terminal amidase YJR063W RPA12 DNA-directed RNA polymerase I, 13.7 KD subunit YJR064W CCT5 T-complex protein 1, epsilon subunit YJR065C ARP3 actin related protein YJR068W RFC2 DNA replication factor C, 41 KD subunit YJR073C OPI3 methylene-fatty-acyl-phospholipid synthase YJR075W HOC1 suppressor of PKC1 YJR076C CDC11 septin YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YJR092W BUD4 budding protein YJR093C FIP1 component of pre-mRNA polyadenylation factor PF I YJR094C IME1 transcription factor required for sporulation YJR094W-A RPL43B 60S large subunit ribosomal protein YJR095W SFC1 succinate-fumarate transporter YJR099W YUH1 ubiquitin-specific protease YJR104C SOD1 copper-zinc superoxide dismutase YJR109C CPA2 arginine-specific carbamoylphosphate synthase, large chain YJR112W NNF1 nuclear envelope protein YJR113C RSM7 similarity to bacterial, chloroplast and mitochondrial ribosomal protein S7 YJR117W STE24 zinc metallo-protease YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YJR122W CAF17 CCR4 associated factor YJR123W RPS5 ribosomal protein S5.e YJR125C ENT3 cytoskeletal adaptor YJR131W MNS1 alpha1,2-mannosidase YJR135W-A TIM8 delivers Proteins across the intermembrane space of mitochondria to the TIM22 complex YJR143C PMT4 dolichyl-phosphate-mannose--protein O-mannosyl transferase YJR144W MGM101 mitochondrial genome maintenance protein YJR145C RPS4A ribosomal protein S4.e.c10 YJR148W BAT2 branched chain amino acid aminotransferase, cytosolic YJR150C DAN1 only expressed under anaerobic conditions YJR151C DAN4 similarity to mucin proteins, YKL224c, Sta1p YJR152W DAL5 allantoate permease YJR158W HXT16 member of the hexose transporter family of the major facilitator superfamily [MFS] YKL002W DID4 class E vacuolar-protein sorting and endocytosis factor YKL003C MRP17 ribosomal protein of the small subunit, mitochondrial YKL005C YKL005C weak similarity to YKR029c and D.melanogaster transcription elongation factor DmS-II YKL006C-A SFT1 SNARE-like protein YKL006W RPL14A ribosomal protein YKL007W CAP1 F-actin capping protein alpha subunit YKL010C UFD4 similarity to rat ubiquitin ligase Nedd4 YKL011C CCE1 cruciform-cutting endonuclease, mitochondrial YKL012W PRP40 splicing factor YKL013C ARC19 subunit of the ARP2/3 complex YKL015W PUT3 positive activator of the proline utilisation pathway YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL019W RAM2 protein farnesyltransferase, alpha subunit YKL020C SPT23 dosage-dependent suppressor of Ty-induced promotor mutations YKL022C CDC16 subunit of anaphase-promoting complex (cyclosome) YKL024C URA6 uridine-monophosphate kinase YKL028W TFA1 TFIIE subunit (transcription initiation factor), 66 kD YKL029C MAE1 malic enzyme YKL032C IXR1 intrastrand crosslink recognition protein and transcription factor YKL038W RGT1 regulator of glucose-induced genes YKL041W VPS24 endosomal Vps protein complex subunit YKL042W SPC42 spindle pole body component YKL043W PHD1 transcription factor YKL045W PRI2 DNA-directed DNA polymerase alpha , 58 KD subunit (DNA primase) YKL049C CSE4 component of the core centromere YKL056C YKL056C strong similarity to human IgE-dependent histamine-releasing factor YKL057C NUP120 nuclear pore protein YKL058W TOA2 TFIIA subunit (transcription initiation factor), 13.5 kD YKL060C FBA1 fructose-bisphosphate aldolase YKL062W MSN4 transcriptional activator YKL064W MNR2 overexpression overcomes manganese toxicity YKL065C YET1 Yeast endoplasmic reticulum 25 kDa transmembrane protein YKL067W YNK1 nucleoside diphosphate kinase YKL068W NUP100 nuclear pore protein YKL073W LHS1 chaperone of the ER lumen YKL074C MUD2 pre-mRNA splicing factor YKL079W SMY1 kinesin-related protein YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL081W TEF4 translation elongation factor eEF1, gamma chain YKL085W MDH1 malate dehydrogenase precursor, mitochondrial YKL087C CYT2 holocytochrome-c1 synthase YKL089W MIF2 required for normal chromosome segregation and spindle integrity YKL095W YJU2 similarity to C.elegans hypothetical proteins YKL096W CWP1 cell wall mannoprotein YKL096W-A CWP2 cell wall mannoprotein YKL101W HSL1 ser/thr protein kinase, coupling septin ring assembly to cell cycle progression YKL103C LAP4 aminopeptidase yscI precursor, vacuolar YKL104C GFA1 glucosamine--fructose-6-phosphate transaminase YKL106W AAT1 aspartate transaminase, mitochondrial YKL108W SLD2 chromosomal DNA replication protein YKL109W HAP4 CCAAT-binding factor subunit YKL112W ABF1 ARS-binding factor YKL113C RAD27 ssDNA endonuclease and 5'-3'exonuclease YKL114C APN1 AP endonuclease YKL119C VPH2 H+-ATPase assembly protein YKL120W OAC1 similarity to mitochondrial uncoupling proteins (MCF) YKL122C SRP21 signal recognition particle subunit YKL125W RRN3 RNA polymerase I specific transcription factor YKL127W PGM1 phosphoglucomutase, minor isoform YKL129C MYO3 myosin type I YKL130C SHE2 required for mother cell-specific expression of HO YKL134C OCT1 mitochondrial intermediate peptidase YKL135C APL2 AP-1 complex subunit, beta1-adaptin, 82 KD YKL138C MRPL31 ribosomal protein YmL31, mitochondrial YKL139W CTK1 carboxy-terminal domain (CTD) kinase, alpha subunit YKL141W SDH3 cytochrome b560 subunit of respiratory complex II YKL142W MRP8 ribosomal protein, mitochondrial YKL144C RPC25 DNA-direcred RNA polymerase III, 25 KD subunit YKL145W RPT1 26S proteasome regulatory subunit YKL148C SDH1 succinate dehydrogenase flavoprotein precursor YKL149C DBR1 lariat-debranching enzyme YKL150W MCR1 cytochrome-b5 reductase YKL152C GPM1 phosphoglycerate mutase YKL154W SRP102 signal recognition particle receptor, beta chain YKL156W RPS27A ribosomal protein S27.e YKL157W APE2 aminopeptidase yscII YKL163W PIR3 member of the PIR1P/Pir2p/PIR3P family YKL164C PIR1 required for tolerance to heat shock YKL166C TPK3 cAMP-dependent protein kinase 3, catalytic chain YKL167C MRP49 ribosomal protein, mitochondrial YKL170W MRPL38 ribosomal protein of the large subunit (L14), mitochondrial YKL178C STE3 pheromone a-factor receptor YKL180W RPL17A ribosomal protein L17.e YKL182W FAS1 fatty-acyl-CoA synthase, beta chain YKL185W ASH1 negative regulator of HO transcription YKL186C MTR2 mRNA transport protein YKL188C PXA2 ABC transporter, peroxisomal YKL190W CNB1 calcineurin B, regulatory subunit YKL192C ACP1 mitochonrial acyl-carrier protein YKL193C SDS22 regulatory subunit for the mitotic function of type I protein phosphatase YKL194C MST1 threonine--tRNA ligase, mitochondrial YKL196C YKT6 SNARE protein for Endoplasmic Reticulum-Golgi transport YKL197C PEX1 peroxisomal assembly protein - peroxin YKL203C TOR2 phosphatidylinositol 3-kinase YKL205W LOS1 pre-tRNA splicing protein YKL208W CBT1 apo-cytochrome b pre-mRNA processing protein YKL209C STE6 ATP-binding cassette transporter protein YKL210W UBA1 E1-like (ubiquitin-activating) enzyme YKL211C TRP3 anthranilate synthase component II YKL212W SAC1 recessive suppressor of secretory defect YKL216W URA1 dihydroorotate dehydrogenase YKL220C FRE2 ferric (and cupric) reductase YKL222C YKL222C weak similarity to transcription factors, similarity to finger proteins YOR162c, YOR172w and YLR266c YKR001C VPS1 member of the dynamin family of GTPases YKR002W PAP1 poly(A) polymerase YKR006C MRPL13 ribosomal protein YmL13, mitochondrial YKR008W RSC4 member of RSC complex, which remodels the structure of chromatin YKR009C FOX2 hydratase-dehydrogenase-epimerase, peroxisomal YKR026C GCN3 translation initiation factor eIF2B, 34 KD, alpha subunit YKR034W DAL80 transcriptional repressor for allantoin and GABA catabolic genes YKR035W-A DID2 class E vacuolar-protein sorting and endocytosis factor YKR037C SPC34 spindle pole body protein YKR039W GAP1 general amino acid permease YKR048C NAP1 nucleosome assembly protein I YKR050W TRK2 moderate-affinity potassium transport protein YKR052C MRS4 RNA splicing protein and member of the mitochondrial carrier family (MCF) YKR054C DYN1 dynein heavy chain, cytosolic YKR056W RNC1 tRNA(m5U54)methyltransferase YKR057W RPS21A ribosomal protein S21.e YKR059W TIF1 translation initiation factor 4A YKR061W KTR2 mannosyltransferase YKR062W TFA2 TFIIE subunit (transcription initiation factor), 43 KD YKR063C LAS1 involved in cell morphogenesis, cytoskeletal regulation and bud formation YKR064W YKR064W weak similarity to transcription factors YKR066C CCP1 cytochrome-c peroxidase precursor YKR068C BET3 involved in targeting and fusion of ER to golgi transport vesicles YKR072C SIS2 involved in cell cycle-specific gene expression YKR080W MTD1 methylenetetrahydrofolate dehydrogenase (NAD+) YKR082W NUP133 nuclear pore protein YKR084C HBS1 translation elongation factor eEF-1 alpha chain homolog YKR085C MRPL20 ribosomal protein YmL20, mitochondrial YKR086W PRP16 RNA-dependent ATPase YKR092C SRP40 suppressor of mutant AC40 of RNA polymerase I and III YKR093W PTR2 peptide transporter YKR094C RPL40B ubiquitin YKR095W MLP1 myosin-like protein related to USO1P YKR097W PCK1 phosphoenolpyruvate carboxykinase YKR099W BAS1 transcription factor YKR101W SIR1 silencing regulatory protein YKR102W FLO10 similarity to FLO1P YLL001W DNM1 dynamin-related protein YLL004W ORC3 origin recognition complex, 62 kDa subunit YLL006W MMM1 required for mitochondrial shape and structure YLL008W DRS1 RNA helicase of the DEAD box family YLL009C COX17 interacts genetically with SCO1 and SCO2 in cytochrome oxidase assembly YLL011W SOF1 involved in 18S pre-rRNA production YLL016W SDC25 GDP/GTP exchange factor (GEF) YLL018C DPS1 aspartyl-tRNA synthetase, cytosolic YLL021W SPA2 involved in cell polarity YLL026W HSP104 heat shock protein YLL036C PRP19 non-snRNP sliceosome component required for DNA repair YLL039C UBI4 ubiquitin YLL041C SDH2 succinate dehydrogenase iron-sulfur protein subunit YLL045C RPL8B 60s large subunit ribosomal protein L7a.e.B YLL048C YBT1 yeast bile transporter YLL050C COF1 cofilin, actin binding and severing protein YLR014C PPR1 transcription factor regulating pyrimidine pathway YLR025W SNF7 class E Vps protein YLR026C SED5 syntaxin (T-SNARE) YLR027C AAT2 aspartate aminotransferase, cytosolic YLR029C RPL15A 60s large subunit ribosomal protein L15.e.c12 YLR032W RAD5 DNA helicase YLR034C SMF3 strong similarity to SMF2 protein and S.pombe hypothetical protein YLR037C DAN2 strong similarity to members of the SRP1P/TIP1P family YLR038C COX12 cytochrome-c oxidase, subunit VIB YLR044C PDC1 pyruvate decarboxylase, isozyme 1 YLR045C STU2 suppressor of a cs tubulin mutation YLR048W RPS0B 40S ribosomal protein p40 homolog B YLR055C SPT8 transcriptional adaptor or co-activator YLR056W ERG3 C-5 sterol desaturase YLR058C SHM2 serine hydroxymethyltransferase, cytoplasmic YLR060W FRS1 phenylalanyl-tRNA synthetase, alpha subunit, cytosolic YLR066W SPC3 signal peptidase subunit YLR067C PET309 required for stability and translation of COX1 mRNA YLR069C MEF1 translation elongation factor G, mitochondrial YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR075W RPL10 60S large subunit ribosomal protein YLR078C BOS1 secretory pathway protein YLR079W SIC1 p40 inhibitor of CDC28P-Clb protein kinase complex YLR081W GAL2 galactose (and glucose) permease YLR083C EMP70 endosomal protein YLR085C ARP6 Actin-related protein YLR088W GAA1 required for attachment of GPI anchor onto proteins YLR093C NYV1 v-SNARE, vacuolar YLR096W KIN2 ser/thr protein kinase YLR098C CHA4 transcription factor YLR103C CDC45 required for minichromosome maintenance and initiation of chromosomal DNA replication YLR105C SEN2 tRNA splicing endonuclease beta subunit YLR109W AHP1 Alkyl hydroperoxide reductase YLR115W CFT2 cleavage and polyadenylation specificity factor, part of CF II YLR116W MSL5 branch point bridging protein YLR120C YPS1 aspergillopepsin YLR126C YLR126C weak similarity to P.aeruginosa anthranilate synthase component II YLR131C ACE2 metallothionein expression activator YLR133W CKI1 choline kinase YLR134W PDC5 pyruvate decarboxylase, isozyme 2 YLR139C SLS1 suppresses lethality of SSM4 deletion YLR141W RRN5 RNA polymerase I specific transcription initiation factor YLR142W PUT1 proline oxidase YLR147C SMD3 spliceosomal snRNA-associated Sm core protein required for pre-mRNA splicing YLR148W PEP3 vacuolar membrane protein YLR155C ASP3A L-asparaginase II YLR157C ASP3B L-asparaginase II YLR158C ASP3C L-asparaginase II YLR160C ASP3D L-asparaginase II YLR163C MAS1 mitochondrial processing peptidase YLR166C SEC10 required for exocytosis YLR167W RPS31 ubiquitin/40S small subunit ribosomal protein YLR168C (MSF1) probably involved in intramitochondrial protein sorting YLR170C APS1 AP-1 complex subunit, sigma1 subunit, 18 KD YLR174W IDP2 isocitrate dehydrogenase, cytosolic YLR175W CBF5 putative rRNA pseuduridine synthase YLR176C RFX1 repressor of DNA damage-inducible genes YLR182W SWI6 transcription factor YLR185W RPL37A ribosomal protein L37.e YLR191W PEX13 peroxisomal protein involved in protein import - peroxin YLR195C NMT1 N-myristoyltransferase YLR197W SIK1 involved in pre-rRNA processing YLR200W YKE2 Gim complex component YLR203C MSS51 possibly involved in translational activation of COX1 and COB mRNA YLR206W ENT2 clathrin binding protein, required for endocytosis YLR208W SEC13 protein transport protein YLR212C TUB4 gamma tubulin YLR214W FRE1 ferric (and cupric) reductase YLR216C CPR6 member of the cyclophilin family YLR220W CCC1 involved in calcium regulation YLR223C IFH1 pre-rRNA processing machinery control protein YLR229C CDC42 GTP-binding protein of RAS superfamily YLR233C EST1 telomere elongation protein YLR234W TOP3 DNA topoisomerase III YLR240W VPS34 phosphatidylinositol 3-kinase YLR242C ARV1 involved in sterol uptake and distribution into the plasma membrane YLR244C MAP1 methionine aminopeptidase, isoform 1 YLR248W RCK2 Ca/calmodulin-dependent ser/thr protein kinase YLR249W YEF3 translation elongation factor eEF3 YLR250W SSP120 secretory protein YLR251W YLR251W similarity to peroxisomal rat membrane protein PMP22 YLR256W HAP1 transcription factor YLR258W GSY2 UDP-glucose--starch glucosyltransferase, isoform 2 YLR259C HSP60 heat shock protein - chaperone, mitochondrial YLR262C YPT6 GTP-binding protein of the rab family YLR263W RED1 meiosis-specific protein YLR264W RPS28B 40S small subunit ribosomal protein S28.e.c12 YLR266C YLR266C weak similarity to transcription factors YLR268W SEC22 synaptobrevin (V-SNARE) YLR272C YCS4 subunit of condensin protein complex YLR274W CDC46 cell division control protein YLR275W SMD2 U1 snRNP protein of the Sm class YLR277C YSH1 component of pre-mRNA polyadenylation factor PF I YLR284C ECI1 delta3-cis-delta2-trans-enoyl-CoA isomerase YLR286C CTS1 endochitinase YLR287C-A RPS30A 40S small subunit ribosomal protein YLR291C GCD7 translation initiation factor eIF2b, 43 kDa subunit YLR292C SEC72 ER protein-translocation complex subunit YLR293C GSP1 GTP-binding protein of the ras superfamily YLR295C ATP14 F1F0-ATPase complex, subunit h YLR298C YHC1 associated with the U1 snRNP complex YLR300W EXG1 exo-beta-1,3-glucanase (I/II), major isoform YLR303W MET17 O-acetylhomoserine sulfhydrylase YLR304C ACO1 aconitate hydratase YLR309C IMH1 involved in vesicular transport YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR312W-A MRPL15 ribosomal protein of the large subunit, mitochondrial YLR313C SPH1 required for bipolar bud site selection YLR314C CDC3 cell division control protein YLR318W EST2 catalytic subunit of the telomerase YLR319C BUD6 bud site selection protein YLR321C SFH1 subunit of the RSC complex YLR325C RPL38 60S large subunit ribosomal protein YLR329W REC102 meiotic recombination protein YLR330W CHS5 chitin synthesis protein YLR333C RPS25B ribosomal protein S25.e.c12 YLR335W NUP2 nuclear pore protein YLR337C VRP1 verprolin YLR340W RPP0 acidic ribosomal protein L10.e YLR342W FKS1 1,3-beta-D-glucan synthase, catalytic subunit YLR344W RPL26A 60S large subunit ribosomal protein YLR347C KAP95 karyopherin-beta YLR348C DIC1 dicarboxylate carrier protein YLR354C TAL1 transaldolase YLR355C ILV5 ketol-acid reducto-isomerase YLR367W RPS22B ribosomal protein S15a.e.c12 YLR369W SSQ1 mitochondrial heat shock protein 70 YLR370C ARC18 subunit of the ARP2/3 complex YLR377C FBP1 fructose-1,6-bisphosphatase YLR378C SEC61 ER protein-translocation complex subunit YLR382C NAM2 leucine--tRNA ligase precursor, mitochondrial YLR388W RPS29A ribosomal protein S29.e.A YLR393W ATP10 F1F0 ATPase complex assembly protein YLR395C COX8 cytochrome-c oxidase chain VIII YLR396C VPS33 vacuolar sorting protein YLR398C SKI2 antiviral protein and putative helicase YLR399C BDF1 sporulation protein YLR403W SFP1 zinc finger protein YLR406C RPL31B 60S large subunit ribosomal protein L31.e.c12 YLR418C CDC73 DNA-directed RNA polymerase II accessory protein YLR429W CRN1 a coronin, that promotes actin polymerization and crosslinking to microtubules YLR430W SEN1 positive effector of tRNA-splicing endonuclease YLR433C CNA1 calcineurin B, catalytic subunit YLR438C-A LSM3 Sm-like (Lsm) protein YLR438W CAR2 ornithine aminotransferase YLR439W MRPL4 ribosomal protein, mitochondrial YLR441C RPS1A ribosomal protein S3a.e YLR442C SIR3 silencing regulatory and DNA-repair protein YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YLR448W RPL6B 60S large subunit ribosomal protein YLR450W HMG2 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 YLR451W LEU3 transcription factor YLR452C SST2 involved in desensitization to alpha-factor pheromone YLR453C RIF2 RAP1P interacting factor 2 YML001W YPT7 GTP-binding protein of the RAB family YML007W YAP1 transcriptional activator involved in oxidative stress response YML008C ERG6 S-adenosyl-methionine delta-24-sterol-c-methyltransferase YML009C MRPL39 60S ribosomal protein, mitochondrial YML010W SPT5 transcription elongation protein YML012W ERV25 component of the COPII-coated vesicles, 25 Kda YML015C TAF40 TFIID subunit (TBP-associated factor), 40KD YML021C UNG1 uracil-DNA glycosylase YML024W RPS17A ribosomal protein S17.e.A YML025C YML6 ribosomal protein, mitochondrial YML026C RPS18B ribosomal protein S18.e.c13 YML027W YOX1 homoeodomain protein YML028W TSA1 thiol-specific antioxidant YML031W NDC1 nuclear envelope protein YML032C RAD52 recombination and DNA repair protein YML042W CAT2 carnitine O-acetyltransferase YML043C RRN11 RNA polymerase I specific transcription initiation factor YML046W PRP39 pre-mRNA splicing factor YML051W GAL80 negative regulator for expression of galactose-induced genes YML054C CYB2 lactate dehydrogenase cytochrome b2 YML055W SPC2 signal peptidase 18 KD subunit YML057W CMP2 calcineurin B, catalytic subunit YML060W OGG1 8-oxoguanine DNA glycosylase YML061C PIF1 DNA helicase involved in mitochondrial DNA repair and telomere length YML062C MFT1 mitochondrial fusion target protein YML063W RPS1B ribosomal protein S3a.e YML065W ORC1 origin recognition complex, 104 KD subunit YML069W POB3 protein that binds to DNA polymerase I (PolI) YML073C RPL6A 60S large subunit ribosomal protein YML074C NPI46 proline cis-trans isomerase YML075C HMG1 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 YML076C YML076C weak similarity to transcription factor YML077W BET5 involved in targeting and fusion of ER to golgi transport vesicles YML078W CPR3 cyclophilin (peptidylprolyl isomerase), mitochondrial YML081C-A ATP18 gene for subunit i/j of the mitochondrial F1F0-ATP synthase YML085C TUB1 alpha-1 tubulin YML091C RPM2 ribonuclease P precursor, mitochondrial YML092C PRE8 20S proteasome subunit Y7 (alpha2) YML094W GIM5 Gim complex component YML095C RAD10 DNA repair protein YML097C VPS9 vacuolar sorting protein YML098W TAF19 TFIID subunit (TBP-associated factor), 19 kD YML099C ARG81 transcription factor involved in arginine metabolism YML100W TSL1 alpha,alpha-trehalose-phosphate synthase, 123 KD subunit YML102W CAC2 chromatin assembly complex, subunit p60 YML103C NUP188 nuclear pore protein YML104C MDM1 intermediate filament protein YML105C SEC65 signal recognition particle subunit YML110C COQ5 ubiquinone biosynthesis, methyltransferase YML112W CTK3 carboxy-terminal domain (CTD) kinase, gamma subunit YML113W DAT1 datin, oligo(dA)/oligo(dT)-binding protein YML115C VAN1 vanadate resistance protein YML116W ATR1 aminotriazole and 4-nitroquinoline resistance protein YML120C NDI1 NADH-ubiquinone-6 oxidoreductase YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YML124C TUB3 alpha-3 tubulin YML129C COX14 cytochrome-c oxidase assembly protein YML130C ERO1 required for protein disulfide bond formation in the ER YMR001C CDC5 involved in regulation of DNA replication YMR004W MVP1 required for vacuolar protein sorting YMR008C PLB1 phospholipase B (lysophospholipase) YMR011W HXT2 high-affinity hexose transporter YMR013C SEC59 dolichol kinase YMR015C ERG5 C-22 sterol desaturase YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR019W STB4 weak similarity to YIL130w, PUT3P and other transcription factors YMR021C MAC1 metal binding activator YMR022W QRI8 E2 ubiquitin-conjugation enzyme YMR023C MSS1 mitochondrial GTPase involved in expression of COX1 YMR024W MRPL3 ribosomal protein of the large subunit, mitochondrial YMR026C PEX12 required for biogenesis of peroxisomes - peroxin YMR032W HOF1 involved in cytokinesis YMR033W ARP9 Actin-related protein YMR035W IMP2 mitochondrial inner membrane protease subunit YMR037C MSN2 stress responsive regulatory protein YMR038C LYS7 copper chaperone for superoxide dismutase SOD1P YMR039C SUB1 transcriptional coactivator YMR042W ARG80 transcription factor involved in arginine metabolism YMR043W MCM1 transcription factor of the MADS box family YMR047C NUP116 nuclear pore protein YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YMR056C AAC1 ADP/ATP carrier protein (MCF) YMR058W FET3 cell surface ferroxidase, high affinity YMR059W SEN15 tRNA splicing endonuclease delta subunit YMR060C TOM37 mitochondrial outer membrane import receptor subunit, 37 kD YMR061W RNA14 component of pre-mRNA 3'-end processing factor CF I YMR062C ECM40 acetylornithine acetyltransferase YMR065W KAR5 nuclear fusion protein YMR072W ABF2 high mobility group protein YMR078C CTF18 required for accurate chromosome transmission in mitosis and maintenance of normal telomere length YMR079W SEC14 phosphatidylinositol(PI)/phosphatidylcholine(PC) transfer protein YMR080C NAM7 nonsense-mediated mRNA decay protein YMR083W ADH3 alcohol dehydrogenase III YMR089C YTA12 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YMR092C AIP1 actin cytoskeleton component YMR094W CTF13 kinetochore protein complex, CBF3, 58 KD subunit YMR105C PGM2 phosphoglucomutase, major isoform YMR106C YKU80 component of DNA end-joining repair pathway YMR108W ILV2 acetolactate synthase YMR109W MYO5 myosin I YMR112C MED11 mediator complex subunit YMR116C ASC1 40S small subunit ribosomal protein YMR117C SPC24 spindle pole body protein YMR121C RPL15B 60S large subunit ribosomal protein L15.e.c13 YMR125W STO1 large subunit of the nuclear cap-binding protein complex CBC YMR128W ECM16 putative DEAH-box RNA helicase YMR129W POM152 nuclear pore membrane glycoprotein YMR133W REC114 meiotic recombination protein YMR137C PSO2 DNA repair protein YMR138W CIN4 GTP-binding protein YMR139W RIM11 ser/thr protein kinase YMR142C RPL13B 60S large subunit ribosomal protein YMR143W RPS16A ribosomal protein S16.e YMR145C NDH1 mitochondrial cytosolically directed NADH dehydrogenase YMR146C TIF34 translation initiation factor eIF3, p39 subunit YMR149W SWP1 oligosaccharyltransferase delta subunit YMR150C IMP1 protease, mitochondrial YMR152W YIM1 mitochondrial inner membrane protease YMR167W MLH1 DNA mismatch repair protein YMR168C CEP3 kinetochore protein complex, 71 KD subunit YMR174C PAI3 protease A (ysca) inhibitor IA3 YMR177W MMT1 mitochondrial gene involved in iron uptake YMR179W SPT21 required for normal transcription at a number of loci YMR182C RGM1 transcriptional repressor protein YMR183C SSO2 syntaxin (T-SNARE) YMR186W HSC82 heat shock protein YMR189W GCV2 glycine decarboxylase P subunit YMR193W MRPL24 ribosomal protein of the large subunit, mitochondrial YMR194W RPL36A 60S large subunit ribosomal protein YMR197C VTI1 v-SNARE: involved in Golgi retrograde protein traffic YMR198W CIK1 spindle pole body associated protein YMR199W CLN1 cyclin, G1/S-specific YMR201C RAD14 nucleotide excision repair protein YMR202W ERG2 C-8 sterol isomerase YMR203W TOM40 forms the hydrophilic channel of the mitochondrial import pore for preproteins YMR205C PFK2 6-phosphofructokinase, beta subunit YMR208W ERG12 mevalonate kinase YMR214W SCJ1 homolog of E. coli DnaJ, functions in the endoplasmic reticulum by interaction with KAR2P YMR218C TRS130 TRAPP subunit of 130 kDa involved in targeting and fusion of ER to golgi transport vesicles YMR220W ERG8 phosphomevalonate kinase YMR224C MRE11 DNA repair and meiotic recombination protein YMR225C MRPL44 ribosomal protein YMR44, mitochondrial YMR227C TAF67 TFIID subunit (TBP-associated factor), 67 kD YMR228W MTF1 RNA polymerase specific factor, mitochondrial YMR229C RRP5 processing of pre-ribosomal RNA YMR230W RPS10B ribosomal protein YMR231W PEP5 vacuolar biogenesis protein YMR235C RNA1 GTPase activating protein YMR236W TAF17 TFIID and SAGA subunit YMR239C RNT1 double-stranded ribonuclease YMR240C CUS1 U2 snRNP protein YMR241W YHM2 yeast suppressor gene of HM (mitochondrial histone) mutant (ABF2) YMR242C RPL20A 60s large subunit ribosomal protein YMR243C ZRC1 zinc- and cadmium resistance protein YMR256C COX7 cytochrome-c oxidase, subunit VII YMR257C PET111 required for translation of COX2 mRNA YMR260C TIF11 translation initiation factor eIF1a YMR261C TPS3 alpha,alpha-trehalose-phosphate synthase, 115 KD subunit YMR267W PPA2 inorganic pyrophosphatase, mitochondrial YMR268C PRP24 pre-mRNA splicing factor YMR270C RRN9 RNA polymerase I specific transcription initiation factor YMR272C SCS7 required for hydroxylation of ceramide YMR276W DSK2 ubiquitin-like protein YMR277W FCP1 TFIIF interacting component of CTD phosphatase YMR280C CAT8 transcription factor involved in gluconeogenesis YMR282C AEP2 required for the expression of subunit-9 of atp synthase YMR284W YKU70 high-affinity DNA-binding protein YMR286W MRPL33 ribosomal protein of the large subunit, mitochondrial YMR287C MSU1 3'-5' exonuclease for RNA 3' ss-tail, mitochondrial YMR294W JNM1 mitosis protein, involved in nuclear migration YMR297W PRC1 carboxypeptidase y, serine-type protease YMR301C ATM1 ATP-binding cassette transporter protein, mitochondrial YMR302C PRP12 involved in early maturation of pre-rRNA YMR303C ADH2 alcohol dehydrogenase II YMR307W GAS1 glycophospholipid-anchored surface glycoprotein YMR308C PSE1 beta karyopherin YMR309C NIP1 associated with 40s ribosomal subunit YMR314W PRE5 20S proteasome subunit(alpha6) YMR319C FET4 low affinity Fe(II) iron transport protein YNL005C MRP7 ribosomal protein YmL2 precursor, mitochondrial YNL007C SIS1 heat shock protein YNL009W IDP3 isocitrate dehydrogenase, NADP-dependent YNL012W SPO1 transcriptional regulator involved in sporulation YNL015W PBI2 proteinase B inhibitor 2 YNL016W PUB1 major polyadenylated RNA-binding protein of nucleus and cytoplasm YNL021W HDA1 histone deacetylase A YNL025C SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YNL030W HHF2 histone H4 YNL031C HHT2 histone H3 YNL037C IDH1 isocitrate dehydrogenase (NAD+) subunit 1, mitochondrial YNL039W BDP1 TFIIIB subunit, 90 kD YNL052W COX5A cytochrome-c oxidase chain V.A precursor YNL054W VAC7 vacuolar protein YNL055C POR1 mitochondrial outer membrane porin YNL059C ARP5 Actin-related protein YNL061W NOP2 nucleolar protein YNL062C GCD10 translation initiation factor eIF3 RNA-binding subunit YNL064C YDJ1 mitochondrial and ER import protein YNL066W SUN4 strong similarity to YIL123w, UTH1P, NCA3P and C. wickerhamii beta-glucosidase protein YNL067W RPL9B ribosomal protein L9.e.c14 YNL068C FKH2 homology to D.melanogaster forkhead protein YNL069C RPL16B 60S large subunit ribosomal protein YNL070W TOM7 mitochondrial outer membrane import receptor subunit, 7 kD YNL071W LAT1 dihydrolipoamide S-acetyltransferase YNL073W MSK1 lysyl-tRNA synthetase, mitochondrial YNL077W YNL077W similarity to dnaJ protein homolog YDJ1 YNL079C TPM1 tropomyosin 1 YNL082W PMS1 DNA mismatch repair protein YNL084C END3 required for endocytosis and cytoskeletal organization YNL088W TOP2 DNA topoisomerase II (ATP-hydrolysing) YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL096C RPS7B strong similarity to ribosomal protein S7 YNL098C RAS2 GTP-binding protein YNL102W POL1 DNA-directed DNA polymerase alpha, 180 KD subunit YNL103W MET4 transcriptional activator of sulfur metabolism YNL104C LEU4 2-isopropylmalalate synthase YNL112W DBP2 ATP-dependent RNA helicase of DEAD box family YNL113W RPC19 DNA-directed RNA polymerase I,III 16 KD subunit YNL117W MLS1 malate synthase 1 YNL121C TOM70 mitochondrial outer membrane specialized import receptor YNL126W SPC98 spindle pole body component YNL130C CPT1 diacylglycerol cholinephosphotransferase YNL131W TOM22 mitochondrial outer membrane import receptor complex subunit YNL134C YNL134C similarity to C.carbonum toxD gene YNL135C FPR1 peptidyl-prolyl cis-trans isomerase, FK506-binding protein YNL137C NAM9 ribosomal protein, mitochondrial YNL138W SRV2 adenylate cyclase-associated protein, 70kDa YNL142W MEP2 high affinity low capacity ammonia permease YNL145W MFA2 mating pheromone a-factor 2 YNL147W LSM7 Sm-like (Lsm) protein YNL148C ALF1 similarity to human tubulin folding cofactor B YNL151C RPC31 DNA-directed RNA polymerase III, 31 KD subunit YNL153C GIM3 Gim complex component YNL154C YCK2 casein kinase I isoform YNL160W YGP1 secreted glycoprotein YNL162W RPL42A ribosomal protein L36a.e YNL167C SKO1 cre-binding bzip protein YNL169C PSD1 phosphatidylserine decarboxylase 1 YNL172W APC1 subunit of anaphase-promoting complex (cyclosome) YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YNL178W RPS3 ribosomal protein S3.e YNL185C MRPL19 ribosomal protein of the large subunit, mitochondrial YNL188W KAR1 cell division control protein YNL189W SRP1 karyopherin-alpha or importin YNL192W CHS1 chitin synthase I YNL199C GCR2 glycolytic genes transcriptional activator YNL202W SPS19 peroxisomal 2,4-dienoyl-CoA reductase YNL204C SPS18 sporulation-specific zinc-finger protein YNL206C RTT106 similarity to structure-specific recognition proteins YNL209W SSB2 heat shock protein of HSP70 family, cytosolic YNL210W MER1 meiotic recombination protein YNL213C YNL213C similarity to hypothetical protein Neurospora crassa YNL214W PEX17 component of the peroxisomal protein translocation - peroxin YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL220W ADE12 adenylosuccinate synthetase YNL221C POP1 protein component of ribonuclease P and ribonuclease MRP YNL222W SSU72 suppressor of cs mutant of SUA7 YNL223W AUT2 essential for autophagy YNL225C CNM67 involved in cytokinesis YNL233W BNI4 bud neck involved YNL236W SIN4 global regulator protein YNL238W KEX2 endoproteinase of late golgi compartment YNL239W LAP3 member of the GAL regulon YNL241C ZWF1 glucose-6-phosphate dehydrogenase YNL243W SLA2 cytoskeleton assembly control protein YNL244C SUI1 translation initiation factor 3 (eIF3) YNL248C RPA49 DNA-directed RNA polymerase A (I) chain, 46 kDa YNL250W RAD50 DNA repair protein YNL251C NRD1 involved in regulation of nuclear pre-mRNA abundance YNL252C MRPL17 ribosomal protein of the large subunit (YmL30), mitochondrial YNL259C ATX1 antioxidant protein and metal homeostasis factor YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL262W POL2 DNA-directed DNA polymerase epsilon, catalytic subunit A YNL267W PIK1 phosphatidylinositol 4-kinase YNL268W LYP1 lysine-specific high-affinity permease YNL270C ALP1 high-affinity permease for basic amino acids YNL271C BNI1 regulator of budding YNL272C SEC2 protein transport protein YNL277W MET2 homoserine O-acetyltransferase YNL282W POP3 involved in processsing of tRNAs and rRNAs YNL284C MRPL10 ribosomal protein of the large subunit, mitochondrial YNL287W SEC21 coatomer complex gamma chain (gamma-COP) of secretory pathway vesicles YNL290W RFC3 DNA replication factor C, 40 kDa subunit YNL291C MID1 involved in Ca2+ influx during mating YNL292W PUS4 pseudouridine synthase YNL301C RPL18B 60S large subunit ribosomal protein L18.e YNL302C RPS19B 40S small subunit ribosomal protein S19.e YNL306W MRPS18 ribosomal protein of the small subunit, mitochondrial YNL312W RFA2 DNA replication factor A, 36 kDa subunit YNL314W DAL82 transcriptional activator for allantoin catabolic genes YNL315C ATP11 F1F0-ATPase complex assembly protein YNL316C PHA2 prephenate dehydratase YNL318C HXT14 hexose transport protein YNL322C KRE1 cell wall protein YNL328C MDJ2 heat shock protein - chaperone YNL329C PEX6 peroxisomal assembly protein YNL330C RPD3 histone deacetylase B YNR001C CIT1 citrate (si)-synthase, mitochondrial YNR003C RPC34 DNA-directed RNA polymerase III, 34 KD subunit YNR006W VPS27 vacuolar protein sorting-associated protein YNR010W CSE2 subunit of RNA polymerase II mediator complex YNR011C PRP2 RNA-dependent ATPase of DEAH box family YNR016C ACC1 acetyl-CoA carboxylase YNR017W MAS6 mitochondrial inner membrane import translocase subunit YNR023W SNF12 component of SWI/SNF global transcription activator complex YNR026C SEC12 GDP/GTP exchange factor for SAR1P YNR035C ARC35 subunit of the ARP2/3 complex YNR038W DBP6 RNA helicase required for 60S ribosomal subunit assembly YNR041C COQ2 para-hydroxybenzoate--polyprenyltransferase YNR044W AGA1 a-agglutinin anchor subunit YNR045W PET494 translational activator, mitochondrial YNR049C MSO1 secretion protein, multicopy suppressor of SEC1 YNR050C LYS9 saccharopine dehydrogenase (NADP+, L-glutamate forming) YNR052C POP2 required for glucose derepression YNR072W HXT17 sugar transport protein YOL001W PHO80 cyclin YOL004W SIN3 transcription regulatory protein YOL005C RPB11 DNA-directed RNA polymerase II subunit, 13.6 kD YOL006C TOP1 DNA topoisomerase I YOL009C MDM12 involved in mitochondrial inheritance YOL012C HTZ1 evolutionarily conserved member of the histone H2A F/Z family of histone variants YOL013C HRD1 involved in degradation of HMG2P YOL016C CMK2 Ca2+/calmodulin-dependent ser/thr protein kinase, type II YOL018C TLG2 member of the syntaxin family of t-SNAREs YOL020W TAT2 high affinity tryptophan transport protein YOL021C DIS3 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YOL023W IFM1 translation initiation factor 2, mitochondrial YOL025W LAG2 involved in determining longevity YOL028C YAP7 involved in transcription activation YOL030W YOL030W strong similarity to glycoprotein GAS1P YOL031C YOL031C weak similarity to Y.lipolytica SLS1 protein precursor YOL033W MSE1 glutamyl-tRNA synthetase, mitochondrial YOL038W PRE6 20S proteasome subunit (alpha4) YOL039W RPP2A acidic ribosomal protein P2.beta YOL040C RPS15 40S small subunit ribosomal protein YOL044W PEX15 required for peroxisome assembly - peroxin YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL058W ARG1 argininosuccinate synthetase YOL059W GPD2 glycerol-3-phosphate dehydrogenase (NAD+), mitochondrial YOL062C APM4 AP-2 complex subunit, mu2 subunit, 55 KD YOL067C RTG1 basic helix-loop-helix transcription factor that regulates CIT2 gene expression YOL069W NUF2 spindle pole body protein YOL076W MDM20 necessary for mitochondrial inheritance and organisation of the actin cytoskeleton YOL077W-A ATP19 subunit K of the dimeric form of mitochondrial F1F0-ATP synthase YOL081W IRA2 GTPase-activating protein for RAS proteins YOL086C ADH1 alcohol dehydrogenase I YOL088C MPD2 protein disulfide isomerase-related protein YOL089C HAL9 transcriptional activator of ENA1 YOL090W MSH2 DNA mismatch repair protein YOL094C RFC4 DNA replication factor C, 37 kDa subunit YOL096C COQ3 enzyme of ubiquinone (coenzyme Q) biosynthesis YOL097C WRS1 tryptophan--tRNA ligase YOL103W ITR2 myo-inositol permease, minor YOL104C NDJ1 meiotic telomere protein YOL105C WSC3 cell wall integrity and stress response component 3 YOL108C INO4 basic helix-loop-helix transcription factor YOL115W TRF4 topoisomerase I-related protein YOL116W MSN1 transcriptional activator YOL120C RPL18A 60S large subunit ribosomal protein S18.e YOL121C RPS19A 40S small subunit ribosomal protein S19.e YOL122C SMF1 manganese transporter YOL123W HRP1 CF Ib (RNA3' Cleavage factor Ib) YOL126C MDH2 malate dehydrogenase, cytoplasmic YOL127W RPL25 ribosomal protein L23a.e YOL130W ALR1 divalent cation transporter YOL133W HRT1 similarity to Lotus RING-finger protein YOL135C MED7 member of RNA Polymerase II transcriptional regulation mediator complex YOL139C CDC33 translation initiation factor eIF4E YOL140W ARG8 acetylornithine aminotransferase YOL145C CTR9 required for G1 cyclin expression YOL147C PEX11 peroxisomal membrane protein - peroxin YOL148C SPT20 member of the TBP class of SPT proteins that alter transcription site selection YOL156W HXT11 low affinity glucose transport protein YOR005C DNL4 DNA ligase IV YOR008C SLG1 required for cell wall integrity and for stress response YOR010C TIR2 cold shock induced protein YOR014W RTS1 potential regulatory subunit of protein phosphatase 2A YOR017W PET127 component of mitochondrial translation system YOR020C HSP10 chaperonin, mitochondrial YOR028C CIN5 transcriptional activator YOR036W PEP12 syntaxin (T-SNARE), vacuolar YOR037W CYC2 cytochrome-c mitochondrial import factor YOR038C HIR2 histone transcription regulator YOR039W CKB2 casein kinase II beta' chain YOR040W GLO4 glyoxalase II (hydroxyacylglutathione hydrolase) YOR045W TOM6 mitochondrial outer membrane import receptor subunit, 6 kD YOR048C RAT1 5'-3' exoribonuclease YOR058C ASE1 microtubule-associated protein (nonmotor) YOR061W CKA2 casein kinase II alpha' chain YOR063W RPL3 60S large subunit ribosomal protein L3.e YOR065W CYT1 cytochrome-c1 YOR067C ALG8 glucosyltransferase YOR069W VPS5 involved in Golgi retention and vacuolar sorting YOR074C CDC21 thymidylate synthase YOR075W UFE1 syntaxin (T-SNARE) of the ER YOR079C ATX2 multicopy suppressor of SOD-linked defects YOR085W OST3 oligosaccharyltransferase gamma subunit YOR089C VPS21 GTP-binding protein YOR095C RKI1 D-ribose-5-phosphate ketol-isomerase YOR096W RPS7A ribosomal protein YOR098C NUP1 nuclear pore protein YOR099W KTR1 mannosyltransferase involved in n-linked and o-linked glycosylation YOR101W RAS1 GTP-binding protein YOR103C OST2 oligosaccharyltransferase epsilon subunit YOR106W VAM3 syntaxin (t-SNARE) YOR110W TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa YOR113W AZF1 asparagine-rich zinc finger protein YOR115C TRS33 TRAPP subunit of 33 kDa involved in targeting and fusion of ER to golgi transport vesicles YOR116C RPO31 DNA-directed RNA polymerase III, 160 KD subunit YOR117W RPT5 26S proteasome regulatory subunit YOR120W GCY1 galactose-induced protein of aldo/keto reductase family YOR122C PFY1 profilin YOR124C UBP2 ubiquitin-specific proteinase YOR125C CAT5 involved in coenzyme Q (ubiquinone) biosynthesis YOR130C ORT1 ornithine transport protein of mitochondria involved in arginine metabolism, member of the mitochondrial carrier family (MCF) YOR133W EFT1 translation elongation factor eEF2 YOR134W BAG7 structural homolog of SAC7P YOR136W IDH2 isocitrate dehydrogenase (NAD+) subunit 2, mitochondrial YOR140W SFL1 transcription factor YOR141C ARP8 Actin-related protein YOR150W MRPL23 ribosomal protein of the large subunit, mitochondrial YOR151C RPB2 DNA-directed RNA polymerase II, 140 kDa chain YOR153W PDR5 pleiotropic drug resistance protein YOR156C NFI1 interacts with CDC12P in 2-hybrid assay YOR157C PUP1 20S proteasome subunit (beta2) YOR158W PET123 ribosomal protein, mitochondrial YOR159C SME1 spliceosomal snRNA-associated Sm core protein required for mRNA splicing, also likely associated with telomerase TLC1 RNA YOR160W MTR10 involved in nuclear protein import YOR162C YRR1 transcription factor YOR167C RPS28A 40S small subunit ribosomal protein S28.e.c15 YOR168W GLN4 glutaminyl-tRNA synthetase YOR174W MED4 transcription regulation mediator YOR176W HEM15 ferrochelatase precursor YOR177C MPC54 meiosis-specific component of the SPB YOR178C GAC1 ser/thr phosphoprotein phosphatase 1, regulatory chain YOR180C DCI1 Enoyl-CoA Hydratase, peroxisomal YOR181W LAS17 component of actin cortical patches YOR182C RPS30B ribosomal protein S30 YOR185C GSP2 GTP-binding protein of the RAS superfamily YOR187W TUF1 translation elongation factor TU, mitochondrial YOR190W SPR1 exo-1,3-beta-glucanase precursor YOR194C TOA1 TFIIA subunit (transcription initiation factor), 32 kD YOR196C LIP5 lipoic acid synthase YOR201C PET56 rRNA (guanosine-2'-O-)-methyltransferase YOR202W HIS3 imidazoleglycerol-phosphate dehydratase YOR204W DED1 ATP-dependent RNA helicase YOR207C RET1 DNA-directed RNA polymerase III, 130 KD subunit YOR208W PTP2 protein-tyrosine-phosphatase YOR210W RPB10 DNA-directed polymerase I, II, III 8.3 subunit YOR211C MGM1 dynamin-like protein YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YOR213C SAS5 subunit of the RSC complex YOR216C RUD3 suppressor of USO1-1 transport defect YOR217W RFC1 DNA replication factor C, 95 KD subunit YOR219C STE13 type IV dipeptidyl aminopeptidase YOR224C RPB8 DNA-directed RNA polymerase I, II, III 16 KD subunit YOR229W WTM2 transcriptional modulator YOR230W WTM1 transcriptional modulator YOR232W MGE1 heat shock protein - chaperone YOR236W DFR1 dihydrofolate reductase YOR239W-A ABP140 actin filament-binding protein YOR250C CLP1 cleavage/polyadenylation factor IA subunit YOR254C SEC63 ER protein-translocation complex subunit YOR257W CDC31 spindle pole body component, centrin YOR259C RPT4 26S proteasome regulatory subunit YOR260W GCD1 translation initiation factor eIF2bgamma subunit YOR261C RPN8 26S proteasome regulatory subunit YOR265W RBL2 beta-tubulin binding protein YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR272W YTM1 microtubule-interacting protein YOR274W MOD5 tRNA isopentenyltransferase YOR276W CAF20 mRNA CAP-binding protein (eIF4F), 20K subunit YOR288C MPD1 disulfide isomerase related protein YOR290C SNF2 component of SWI/SNF global transcription activator complex YOR293W RPS10A ribosomal protein S10.e YOR301W RAX1 similarity to S. pombe SPAC23G3.05c YOR302W YOR302W CPA1 leader peptide YOR303W CPA1 arginine-specific carbamoylphosphate synthase, small chain YOR310C NOP58 required for pre-18S rRNA processing YOR312C RPL20B 60S large subunit ribosomal protein YOR316C COT1 cobalt accumulation protein YOR319W HSH49 essential yeast splicing factor YOR321W PMT3 mannosyltransferase YOR326W MYO2 myosin heavy chain YOR327C SNC2 synaptobrevin (v-SNARE) homolog present on post-Golgi vesicles YOR328W PDR10 member of ATP-binding cassette (ABC) superfamily YOR330C MIP1 DNA-directed DNA polymerase gamma catalytic subunit, mitochondrial YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YOR334W MRS2 RNA splicing protein and member of the mitochondrial carrier family (MCF) YOR335C ALA1 alanyl-tRNA synthetase, cytosolic YOR336W KRE5 killer toxin-resistance protein YOR337W TEA1 TY1 enhancer activator YOR340C RPA43 DNA-directed RNA polymerase I, 36 KD subunit YOR341W RPA190 DNA-directed RNA polymerase I, 190 KD alpha subunit YOR344C TYE7 basic helix-loop-helix transcription factor YOR348C PUT4 proline and gamma-aminobutyrate permease YOR349W CIN1 chromosome segregation protein YOR351C MEK1 ser/thr protein kinase YOR357C GRD19 involved in retrieval of late Golgi membrane proteins from the prevacuolar compartment YOR358W HAP5 CCAAT-binding factor subunit YOR360C PDE2 high affinity 3',5'-cyclic-nucleotide phosphodiesterase YOR361C PRT1 translation initiation factor eIF3 subunit YOR362C PRE10 20S proteasome subunit C1 (alpha7) YOR363C PIP2 peroxisome proliferating transcription factor YOR369C RPS12 40S small subunit acidic ribosomal protein S12 YOR370C MRS6 geranylgeranyltransferase regulatory subunit YOR373W NUD1 cell cycle regulatory protein YOR375C GDH1 glutamate dehydrogenase (NADP+) YOR386W PHR1 deoxyribodipyrimidine photo-lyase YPL001W HAT1 histone acetyltransferase subunit YPL008W CHL1 protein of the DEAH box family YPL010W RET3 coatomer complex zeta chain YPL013C YPL013C strong similarity to N.crassa mitochondrial ribosomal protein S24 YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL022W RAD1 component of the nucleotide excision repairosome YPL028W ERG10 acetyl-CoA C-acetyltransferase, cytosolic YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL031C PHO85 cyclin-dependent protein kinase YPL036W PMA2 H+-transporting P-type ATPase, minor isoform, plasma membrane YPL037C EGD1 GAL4 DNA-binding enhancer protein YPL040C ISM1 isoleucine--tRNA ligase, mitochondrial YPL042C SSN3 cyclin-dependent CTD kinase YPL043W NOP4 nucleolar protein YPL045W VPS16 vacuolar sorting protein YPL046C ELC1 Elongin C transcription elongation factor YPL048W CAM1 translation elongation factor eEF1 gamma homologue YPL049C DIG1 MAP kinase-associated protein, down-regulator of invasive growth and mating YPL050C MNN9 required for complex N-glycosylation YPL061W ALD6 aldehyde dehydrogenase, cytosolic YPL065W VPS28 involved in vacuolar traffic YPL075W GCR1 transcriptional activator YPL076W GPI2 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL079W RPL21B ribosomal protein L21 YPL081W RPS9A ribosomal protein S9.e.A YPL082C MOT1 transcriptional accessory protein YPL083C SEN54 tRNA splicing endonuclease alpha subunit YPL085W SEC16 multidomain vesicle coat protein YPL089C RLM1 transcription factor of the MADS box family YPL090C RPS6A ribosomal protein S6.e YPL092W SSU1 sulfite sensitivity protein YPL094C SEC62 ER protein-translocation complex subunit YPL097W MSY1 tyrosyl-tRNA synthetase YPL104W MSD1 aspartate--tRNA ligase, mitochondrial YPL105C YPL105C similarity to SMY2P YPL106C SSE1 heat shock protein of HSP70 family YPL111W CAR1 arginase YPL117C IDI1 isopentenyl-diphosphate delta-isomerase YPL118W MRP51 mitochondrial ribosomal protein of the small subunit YPL119C DBP1 ATP-dependent RNA helicase YPL122C TFB2 TFIIH subunit (transcription/repair factor) YPL124W NIP29 nuclear import protein YPL126W NAN1 weak similarity to fruit fly TFIID subunit p85 YPL127C HHO1 histone H1 protein YPL128C TBF1 telomere TTAGGG repeat-binding factor 1 YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL131W RPL5 60S large subunit ribosomal protein L5.e YPL132W COX11 cytochrome-c oxidase assembly protein YPL133C YPL133C weak similarity to transcription factors YPL139C UME1 negative regulator of meiosis YPL143W RPL33A ribosomal protein L35a.e.c16 YPL145C KES1 involved in ergosterol biosynthesis YPL147W PXA1 long-chain fatty acid transporter YPL149W APG5 involved in autophagy and nutrient starvation YPL153C RAD53 ser/thr/tyr protein kinase YPL154C PEP4 aspartyl protease YPL155C KIP2 kinesin-related protein YPL160W CDC60 leucine--tRNA ligase, cytosolic YPL167C REV3 DNA-directed DNA polymerase zeta subunit YPL169C MEX67 factor for nuclear mRNA export YPL172C COX10 farnesyl transferase YPL173W MRPL40 ribosomal protein of the large subunit (YmL40), mitochondrial YPL174C NIP100 component of the dynactin complex YPL175W SPT14 N-acetylglucosaminyltransferase YPL176C SSP134 similarity to chinese hamster transferrin receptor protein YPL177C CUP9 involved in copper homeostasis repression of protein import YPL178W CBC2 small subunit of the nuclear cap-binding protein complex CBC YPL183W-A YPL183W-A strong similarity to mitochondrial and bacterial ribosomal L36 proteins YPL187W MFALPHA1 mating pheromone alpha-1 precursor YPL190C NAB3 polyadenylated RNA-binding protein YPL198W RPL7B 60S large subunit ribosomal protein YPL204W HRR25 casein kinase I, ser/thr/tyr protein kinase YPL210C SRP72 signal recognition particle protein YPL211W NIP7 required for efficient 60S ribosome subunit biogenesis YPL212C PUS1 pseudouridine synthase 1 YPL215W CBP3 required for assembly of cytochrome bc1 complex YPL218W SAR1 GTP-binding protein of the ARF family YPL220W RPL1A ribosomal protein YPL224C MMT2 mitochondrial iron transporter YPL227C ALG5 dolichol-P-glucose synthetase YPL231W FAS2 fatty-acyl-CoA synthase, alpha chain YPL232W SSO1 syntaxin-related protein YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPL237W SUI3 translation initiation factor eIF2 beta subunit YPL240C HSP82 heat shock protein YPL241C CIN2 involved in chromosome segregation YPL242C IQG1 involved in cytokinesis, has similarity to mammalian IQGAP proteins YPL243W SRP68 signal recognition particle protein YPL248C GAL4 transcription factor YPL249C-A RPL36B 60S large subunit ribosomal protein YPL254W HFI1 transcriptional coactivator YPL255W BBP1 cell division control protein YPL256C CLN2 cyclin, G1/S-specific YPL259C APM1 AP-1 complex subunit, mu1 subunit, 54 KD YPL262W FUM1 fumarate hydratase YPL265W DIP5 dicarboxylic amino acid permease YPL266W DIM1 rRNA (adenine-N6,N6-)-dimethyltransferase YPL269W KAR9 cortical protein required for cytoplasmic microtubule orientation and nuclear migration YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPR001W CIT3 citrate (si)-synthase, mitochondrial YPR004C YPR004C strong similarity to electron transfer flavoproteins alpha chain YPR005C HAL1 salt-induced protein YPR010C RPA135 DNA-directed RNA polymerase I, 135 KD subunit YPR016C TIF6 translation initiation factor 6 (eIF6) YPR017C DSS4 GDP/GTP exchange factor for SEC4P YPR018W RLF2 chromatin assembly complex, subunit p90 YPR019W CDC54 member of the CDC46P/MCM2P/MCM3P family YPR020W ATP20 subunit G of the dimeric form of mitochondrial F1F0-ATP Synthase YPR024W YME1 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YPR025C CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPR026W ATH1 acid trehalase, vacuolar YPR032W SRO7 polarized exocytosis by regulating SNARE function YPR033C HTS1 histidine--tRNA ligase, mitochondrial YPR034W ARP7 component of SWI-SNF global transcription activator complex and RSC chromatin remodeling complex YPR035W GLN1 glutamate--ammonia ligase YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar YPR037C ERV2 similarity to ERV1P and rat ALR protein YPR041W TIF5 translation initiation factor eIF5 YPR043W RPL43A ribosomal protein L37a.e YPR045C YPR045C similarity to C.elegans hypothetical protein YPR047W MSF1 phenylalanine--tRNA ligase alpha chain, mitochondrial YPR051W MAK3 N-acetyltransferase YPR052C NHP6A nonhistone chromosomal protein related to mammalian HMG1 YPR055W SEC8 protein transport protein YPR056W TFB4 component of RNA polymerase transcription initiation TFIIH factor YPR057W BRR1 involved in snRNP biogenesis YPR058W YMC1 mitochondrial carrier protein (MCF) YPR060C ARO7 chorismate mutase YPR065W ROX1 heme-dependent transcriptional repressor of hypoxic genes YPR074C TKL1 transketolase 1 YPR080W TEF1 translation elongation factor eEF1 alpha-A chain, cytosolic YPR086W SUA7 TFIIB subunit (transcription initiation factor), factor E YPR088C SRP54 signal recognition particle subunit YPR101W SNT309 splicing factor YPR102C RPL11A ribosomal protein L11.e YPR103W PRE2 20S proteasome subunit (beta5) YPR104C FHL1 transcriptional activator of the forkhead/hnf3 family YPR108W RPN7 subunit of the regulatory particle of the proteasome YPR110C RPC40 DNA-directed RNA polymerase I, III 40 KD subunit YPR113W PIS1 CDP diacylglycerol--inositol 3-phosphatidyltransferase YPR124W CTR1 copper transport protein YPR132W RPS23B 40S small subunit ribosomal protein S23.e YPR133C IWS1 similarity to C.elegans hypothetical protein YPR133W-A TOM5 mitochondrial outer membrane protein YPR134W MSS18 splicing protein YPR135W CTF4 DNA-directed DNA polymerase alpha-binding protein YPR141C KAR3 kinesin-related protein YPR145W ASN1 asparagine synthetase YPR159W KRE6 glucan synthase subunit YPR160W GPH1 glycogen phosphorylase YPR162C ORC4 origin recognition complex, 56 KD subunit YPR163C TIF3 translation initiation factor eIF4B YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins YPR166C MRP2 ribosomal protein S14 YPR168W NUT2 negative transcription regulator from artifical reporters YPR173C VPS4 vacuolar sorting protein YPR175W DPB2 DNA-directed DNA polymerase epsilon, subunit B YPR178W PRP4 U4/U6 snRNP 52 KD protein YPR181C SEC23 component of COPII coat of ER-golgi vesicles YPR182W SMX3 snRNA-associated protein of the SM family YPR183W DPM1 dolichyl-phosphate beta-D-mannosyltransferase YPR186C PZF1 TFIIIA (transcription initiation factor) YPR187W RPO26 DNA-directed RNA polymerase I, II, III 18 KD subunit YPR189W SKI3 antiviral protein YPR190C RPC82 DNA-directed RNA polymerase III, 82 KD subunit YPR191W QCR2 ubiquinol--cytochrome-c reductase 40KD chain II YPR196W YPR196W strong similarity to regulatory protein Mal63p YPR201W ARR3 involved in arsenite transport Q0045 COX1 cytochrome-c oxidase subunit I Q0050 AI1 COX1 intron 1 protein Q0055 AI2 COX1 intron 2 protein Q0060 AI3 DNA endonuclease Q0065 AI4 DNA endonuclease Q0070 AI5_ALPHA DNA endonuclease AI5_ALPHA Q0075 AI5_BETA COX1 intron protein aI5-beta Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0105 COB ubiquinol-cytochrome-c reductase subunit (cytochrome B) Q0110 BI2 mRNA maturase BI2 Q0115 BI3 mRNA maturase BI3 Q0120 BI4 mRNA maturase BI4 Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 Q0140 VAR1 mitochondrial ribosomal protein Q0160 SCEI DNA endonuclease in 21S rRNA intron Q0250 COX2 cytochrome-c oxidase subunit II Q0275 COX3 cytochrome-c oxidase chain III cell wall (38 ORFs) 40.01 38 YAL063C FLO9 strong similarity to FLO1P YAR050W FLO1 cell wall protein involved in flocculation YBR040W FIG1 required for efficient mating YBR067C TIP1 esterase YBR093C PHO5 repressible acid phosphatase precursor YBR301W DAN3 cell wall mannoprotein YCR089W FIG2 required for efficient mating YDR134C YDR134C strong similarity to FLO1P, FLO5P, FLO9P and YLR110c YDR261C EXG2 exo-beta-1,3-glucanase minor isoform YER011W TIR1 cold-shock induced protein of the TIR1P,TIP1P family YFL017C GNA1 essential acetyltransferase YFL051C YFL051C strong similarity to FLO1P, FLO5P and FLO9P - putative pseudogene YGL032C AGA2 a-agglutinin binding subunit YGR189C CRH1 family of putative glycosidases might exert a common role in cell wall organization YGR282C BGL2 endo-beta-1,3-glucanase of the cell wall YHR139C SPS100 sporulation-specific wall maturation protein YIR019C MUC1 extracellular alpha-1,4-glucan glucosidase YJL062W LAS21 required for addition of a side chain to the glycosylphospatidylinositol (GPI) core structure YJL159W HSP150 member of the PIR1P/HSP150P/PIR3P family YJR092W BUD4 budding protein YJR150C DAN1 only expressed under anaerobic conditions YJR151C DAN4 similarity to mucin proteins, YKL224c, Sta1p YKL096W CWP1 cell wall mannoprotein YKL096W-A CWP2 cell wall mannoprotein YKL163W PIR3 member of the PIR1P/Pir2p/PIR3P family YKL164C PIR1 required for tolerance to heat shock YKR102W FLO10 similarity to FLO1P YLR037C DAN2 strong similarity to members of the SRP1P/TIP1P family YLR155C ASP3A L-asparaginase II YLR157C ASP3B L-asparaginase II YLR158C ASP3C L-asparaginase II YLR160C ASP3D L-asparaginase II YNL066W SUN4 strong similarity to YIL123w, UTH1P, NCA3P and C. wickerhamii beta-glucosidase protein YOL030W YOL030W strong similarity to glycoprotein GAS1P YOL105C WSC3 cell wall integrity and stress response component 3 YOR010C TIR2 cold shock induced protein YOR190W SPR1 exo-1,3-beta-glucanase precursor YOR301W RAX1 similarity to S. pombe SPAC23G3.05c plasma membrane (145 ORFs) 40.02 145 YAL041W CDC24 GTP/GDP exchange factor for CDC42P YBL042C FUI1 uridine transport protein YBR021W FUR4 uracil permease YBR023C CHS3 chitin synthase III YBR038W CHS2 chitin synthase II YBR041W FAT1 very long-chain fatty acyl-CoA synthetase YBR068C BAP2 leucine permease, high-affinity (S1) YBR069C TAT1 amino acid permease YBR140C IRA1 inhibitory regulator protein of the ras-cyclic AMP pathway YBR294W SUL1 high-affinity sulfate transport protein YBR298C MAL31 maltose permease YCL025C AGP1 asparagine and glutamine permease YCL027W FUS1 cell fusion protein YCR011C ADP1 ATP-dependent permease YCR021C HSP30 heat shock protein YCR024C-A PMP1 H+-ATPase subunit, plasma membrane YCR034W FEN1 fatty acid elongase required for sphingolipid formation YCR038C BUD5 GDP/GTP exchange factor for RSR1P/Bud1p YCR098C GIT1 glycerophosphoinositol transporter YDL035C GPR1 G-protein coupled receptor YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL210W UGA4 GABA-specific high-affinity permease YDL245C HXT15 strong similarity to HXT17P and HXT7P YDR011W SNQ2 multidrug resistance protein YDR033W MRH1 membrane protein related to HSP30P YDR046C BAP3 valine transporter YDR077W SED1 abundant cell surface glycoprotein YDR122W KIN1 ser/thr protein kinase YDR144C MKC7 aspartyl protease of the periplasmic space YDR208W MSS4 phosphatidylinositol-4-phosphate 5-kinase YDR342C HXT7 high-affinity hexose transporter YDR343C HXT6 high-affinity hexose transporter YDR345C HXT3 low-affinity hexose transporter YDR420W HKR1 Hansenula MrakII k9 killer toxin-resistance protein YDR497C ITR1 myo-inositol permease, major YDR536W STL1 member of the sugar permease family YEL017C-A PMP2 H+-ATPase subunit, plasma membrane YEL063C CAN1 amino acid permease YEL069C HXT13 high-affinity hexose transporter YER008C SEC3 component of exocyst complex YER056C FCY2 purine-cytosine permease YER118C SHO1 involved in the HOG1 high-osmolarity signal transduction pathway YER123W YCK3 casein kinase, isoform 3 YER125W RSP5 hect domain E3 ubiquitin-protein ligase YER145C FTR1 iron permease that mediates high-affinity iron uptake YFL005W SEC4 GTP-binding protein of the ras superfamily YFL011W HXT10 hexose transporter YFL026W STE2 pheromone alpha-factor receptor YFL041W FET5 multicopy oxidase YFL050C ALR2 divalent cation transprter YGL008C PMA1 H+-transporting P-type ATPase, major isoform, plasma membrane YGL077C HNM1 choline permease YGL233W SEC15 vesicular traffic control protein YGR009C SEC9 protein transport protein YGR014W MSB2 multicopy suppressor of a CDC24 bud emergence defect YGR032W GSC2 1,3-beta-D-glucan synthase subunit YGR055W MUP1 high affinity methionine permease YGR121C MEP1 ammonia permease of high capacity and moderate affinity YGR152C RSR1 GTP-binding protein YGR191W HIP1 histidine permease YGR241C YAP1802 Yeast Adaptor Protein, member of AP180 protein family YGR281W YOR1 ATP-binding cassette transporter protein YHL016C DUR3 urea transport protein YHL019C APM2 involved in clathrin-independent transport processes YHL036W MUP3 very low affinity methionine permease YHR005C GPA1 GTP-binding protein alpha subunit of the pheromone pathway YHR092C HXT4 moderate- to low-affinity glucose transporter YHR094C HXT1 low-affinity hexose transporter YHR096C HXT5 member of the hexose transporter family YHR135C YCK1 casein kinase I isoform YHR161C YAP1801 Yeast Adaptor Protein, member of AP180 protein family YIL013C PDR11 membrane transporter YIL047C SYG1 member of the major facilitator superfamily YIL068C SEC6 protein transport protein YIL140W AXL2 required for axial pattern of budding YIL147C SLN1 two-component signal transducer YIL170W HXT12 strong similarity to sugar transport proteins YIR028W DAL4 allantoin permease YJL005W CYR1 adenylate cyclase YJL093C TOK1 outward-rectifier potassium channel YJL129C TRK1 potassium transport protein TRK1P, high-affinity YJL214W HXT8 hexose transport protein YJL219W HXT9 hexose transport protein YJR004C SAG1 alpha-agglutinin YJR040W GEF1 voltage-gated chloride channel protein YJR086W STE18 GTP-binding protein gamma subunit of the pheromone pathway YJR152W DAL5 allantoate permease YJR158W HXT16 member of the hexose transporter family of the major facilitator superfamily [MFS] YKL178C STE3 pheromone a-factor receptor YKL209C STE6 ATP-binding cassette transporter protein YKL220C FRE2 ferric (and cupric) reductase YKR039W GAP1 general amino acid permease YKR050W TRK2 moderate-affinity potassium transport protein YKR093W PTR2 peptide transporter YLL016W SDC25 GDP/GTP exchange factor (GEF) YLR081W GAL2 galactose (and glucose) permease YLR096W KIN2 ser/thr protein kinase YLR120C YPS1 aspergillopepsin YLR166C SEC10 required for exocytosis YLR214W FRE1 ferric (and cupric) reductase YLR229C CDC42 GTP-binding protein of RAS superfamily YLR242C ARV1 involved in sterol uptake and distribution into the plasma membrane YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR342W FKS1 1,3-beta-D-glucan synthase, catalytic subunit YLR452C SST2 involved in desensitization to alpha-factor pheromone YML116W ATR1 aminotriazole and 4-nitroquinoline resistance protein YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YMR008C PLB1 phospholipase B (lysophospholipase) YMR011W HXT2 high-affinity hexose transporter YMR058W FET3 cell surface ferroxidase, high affinity YMR183C SSO2 syntaxin (T-SNARE) YMR243C ZRC1 zinc- and cadmium resistance protein YMR307W GAS1 glycophospholipid-anchored surface glycoprotein YMR319C FET4 low affinity Fe(II) iron transport protein YNL098C RAS2 GTP-binding protein YNL142W MEP2 high affinity low capacity ammonia permease YNL154C YCK2 casein kinase I isoform YNL173C MDG1 GTP-binding protein of the pheromone-response pathway YNL192W CHS1 chitin synthase I YNL239W LAP3 member of the GAL regulon YNL268W LYP1 lysine-specific high-affinity permease YNL270C ALP1 high-affinity permease for basic amino acids YNL291C MID1 involved in Ca2+ influx during mating YNL318C HXT14 hexose transport protein YNL322C KRE1 cell wall protein YNR044W AGA1 a-agglutinin anchor subunit YNR072W HXT17 sugar transport protein YOL020W TAT2 high affinity tryptophan transport protein YOL081W IRA2 GTPase-activating protein for RAS proteins YOL103W ITR2 myo-inositol permease, minor YOL122C SMF1 manganese transporter YOL130W ALR1 divalent cation transporter YOL156W HXT11 low affinity glucose transport protein YOR008C SLG1 required for cell wall integrity and for stress response YOR153W PDR5 pleiotropic drug resistance protein YOR212W STE4 GTP-binding protein beta subunit of the pheromone pathway YOR328W PDR10 member of ATP-binding cassette (ABC) superfamily YOR348C PUT4 proline and gamma-aminobutyrate permease YPL036W PMA2 H+-transporting P-type ATPase, minor isoform, plasma membrane YPL092W SSU1 sulfite sensitivity protein YPL176C SSP134 similarity to chinese hamster transferrin receptor protein YPL232W SSO1 syntaxin-related protein YPL265W DIP5 dicarboxylic amino acid permease YPR124W CTR1 copper transport protein YPR201W ARR3 involved in arsenite transport cytoplasm (554 ORFs) 40.03 554 YAL003W EFB1 translation elongation factor eEF1beta YAL005C SSA1 heat shock protein of HSP70 family, cytosolic YAL012W CYS3 cystathionine gamma-lyase YAL013W DEP1 regulator of phospholipid metabolism YAL035W FUN12 general translation factor eIF2 homolog YAL038W CDC19 pyruvate kinase YAL040C CLN3 cyclin, G1/S-specific YBL007C SLA1 cytoskeleton assembly control protein YBL015W ACH1 acetyl-CoA hydrolase YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBL023C MCM2 member of the MCM2P,MCM3P,CDC46P family YBL027W RPL19B 60S large subunit ribosomal protein L19.e YBL039C URA7 CTP synthase 1 YBL050W SEC17 transport vesicle fusion protein YBL072C RPS8A ribosomal protein S8.e YBL075C SSA3 heat shock protein of HSP70 family, cytosolic YBL076C ILS1 isoleucyl-tRNA synthetase YBL078C AUT7 essential for autophagy YBL087C RPL23A 60S large subunit ribosomal protein L23.e YBL091C MAP2 methionine aminopeptidase, isoform 2 YBL092W RPL32 60S large subunit ribosomal protein L32.e YBL105C PKC1 ser/thr protein kinase YBR011C IPP1 inorganic pyrophosphatase, cytoplasmic YBR017C KAP104 beta-karyopherin YBR018C GAL7 UDP-glucose--hexose-1-phosphate uridylyltransferase YBR019C GAL10 UDP-glucose 4-epimerase YBR020W GAL1 galactokinase YBR031W RPL4A ribosomal protein YBR048W RPS11B ribosomal protein S11.e.B YBR072W HSP26 heat shock protein YBR079C RPG1 translation initiation factor eIF3 (p110 subunit) YBR080C SEC18 vesicular-fusion protein, functional homolog of NSF YBR082C UBC4 E2 ubiquitin-conjugating enzyme YBR084C-A RPL19A 60S large subunit ribosomal protein L19.e YBR102C EXO84 exocyst protein essential for secretion YBR115C LYS2 L-aminoadipate-semialdehyde dehydrogenase, large subunit YBR117C TKL2 transketolase 2 YBR118W TEF2 translation elongation factor eEF1 alpha-A chain, cytosolic YBR121C GRS1 glycine--tRNA ligase YBR126C TPS1 alpha,alpha-trehalose-phosphate synthase, 56 KD subunit YBR130C SHE3 required for mother cell-specific expression of HO YBR143C SUP45 translational release factor YBR164C ARL1 ADP-ribosylation factor YBR166C TYR1 prephenate dehydrogenase (NADP+) YBR168W YBR168W weak similarity to hypothetical protein YLR324w YBR169C SSE2 heat shock protein of the HSP70 family YBR181C RPS6B ribosomal protein S6.e YBR189W RPS9B ribosomal protein S9.e.B YBR191W RPL21A ribosomal protein L21.e YBR196C PGI1 glucose-6-phosphate isomerase YBR218C PYC2 pyruvate carboxylase 2 YBR249C ARO4 2-dehydro-3-deoxyphosphoheptonate aldolase, tyrosine-inhibited YBR299W MAL32 alpha-glucosidase YCL018W LEU2 beta-isopropyl-malate dehydrogenase YCL040W GLK1 aldohexose specific glucokinase YCL057W PRD1 proteinase yscD YCR012W PGK1 phosphoglycerate kinase YCR031C RPS14A 40S Ribosomal protein S14.e YCR053W THR4 threonine synthase (o-p-homoserine p-lyase) YCR057C PWP2 periodic tryptophan protein YCR077C PAT1 topoisomerase II-associated protein YDL022W GPD1 glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic YDL040C NAT1 protein N-acetyltransferase subunit YDL045C FAD1 flavin adenine dinucleotide (FAD) synthetase YDL058W USO1 intracellular protein transport protein YDL061C RPS29B ribosomal protein S29.e.B YDL065C PEX19 required for biogenesis of peroxisomes - peroxin YDL075W RPL31A 60S large subunit ribosomal protein L31.e YDL081C RPP1A 60S large subunit acidic ribosomal protein a1 YDL082W RPL13A 60S large subunit ribosomal protein L13 YDL083C RPS16B ribosomal protein S16.e YDL090C RAM1 protein farnesyltransferase, beta subunit YDL092W SRP14 signal recognition particle subunit YDL122W UBP1 ubiquitin-specific protease YDL130W RPP1B 60S large subunit acidic ribosomal protein L44prime YDL133C-A RPL41B ribosomal protein YDL135C RDI1 rho GDP dissociation inhibitor with activity toward RHO1P YDL136W RPL35B 60S large subunit ribosomal protein YDL143W CCT4 component of chaperonin-containing T-complex YDL184C RPL41A ribosomal protein YDL191W RPL35A 60S large subunit ribosomal protein YDL205C HEM3 porphobilinogen deaminase YDL207W GLE1 RNA export mediator YDL215C GDH2 NAD-specific glutamate dehydrogenase (NAD) YDL229W SSB1 heat shock protein of HSP70 family YDL230W PTP1 protein tyrosine phosphatase YDL236W PHO13 4-nitrophenylphosphatase YDR001C NTH1 neutral trehalase (alpha,alpha-trehalase) YDR002W YRB1 ran-specific GTPase-activating protein YDR007W TRP1 phosphoribosylanthranilate isomerase YDR012W RPL4B ribosomal protein L4.e.B YDR023W SES1 seryl-tRNA synthetase, cytosolic YDR025W RPS11A ribosomal protein S11.e YDR035W ARO3 2-dehydro-3-deoxyphosphoheptonate aldolase, phenylalanine-inhibited YDR037W KRS1 lysyl-tRNA synthetase, cytosolic YDR044W HEM13 coproporphyrinogen III oxidase YDR047W HEM12 uroporphyrinogen decarboxylase YDR050C TPI1 triose-phosphate isomerase YDR059C UBC5 E2 ubiquitin-conjugating enzyme YDR064W RPS13 ribosomal protein YDR074W TPS2 alpha,alpha-trehalose-phosphate synthase, 102 KD subunit YDR081C PDC2 pyruvate decarboxylase regulatory protein YDR110W FOB1 DNA replication fork blocking protein YDR120C TRM1 N2,N2-dimethylguanine tRNA methyltransferase YDR127W ARO1 arom pentafunctional enzyme YDR142C PEX7 peroxisomal import protein - peroxin YDR155C CPH1 cyclophilin (peptidylprolyl isomerase) YDR166C SEC5 required for exocytosis YDR170C SEC7 component of non-clathrin vesicle coat YDR172W SUP35 eukaryotic peptide chain release factor GTP-binding subunit YDR177W UBC1 E2 ubiquitin-conjugating enzyme YDR182W CDC1 cell division control protein YDR188W CCT6 component of chaperonin-containing T-complex (zeta subunit) YDR189W SLY1 hydrophilic suppressor of YPT1 and member of the SEC1P family YDR211W GCD6 translation initiation factor eIF2b epsilon, 81 kDa subunit YDR212W TCP1 component of chaperonin-containing T-complex YDR226W ADK1 adenylate kinase, cytosolic YDR233C YDR233C similarity to hypothetical protein YDL204w YDR244W PEX5 peroxisomal targeting signal receptor YDR272W GLO2 glyoxalase II (hydroxyacylglutathione hydrolase) YDR283C GCN2 ser/thr protein kinase YDR293C SSD1 involved in the tolerance to high concentration of Ca2+ YDR300C PRO1 glutamate 5-kinase YDR303C RSC3 similarity to transcriptional regulator proteins YDR321W ASP1 asparaginase YDR341C YDR341C arginyl-tRNA synthetase, cytosolic YDR354W TRP4 anthranilate phosphoribosyltransferase YDR372C YDR372C similarity to hypothetical S. pombe protein YDR382W RPP2B 60S large subunit acidic ribosomal protein YDR385W EFT2 translation elongation factor eEF2 YDR408C ADE8 phosphoribosylglycinamide formyltransferase (GART) YDR418W RPL12B 60S large subunit ribosomal protein L12.e YDR429C TIF35 translation initiation factor eIF3 (p33 subunit) YDR447C RPS17B ribosomal protein S17.e.B YDR450W RPS18A ribosomal protein S18.e.c4 YDR471W RPL27B 60S large subunit ribosomal protein YDR477W SNF1 carbon catabolite derepressing ser/thr protein kinase YDR500C RPL37B ribosomal protein L.37.e YDR513W TTR1 glutaredoxin YEL003W GIM4 Gim complex component YEL011W GLC3 1,4-glucan branching enzyme (glycogen branching enzyme) YEL032W MCM3 replication initiation protein YEL034W HYP2 translation initiation factor eIF5A.1 YEL047C FRDS1 soluble fumarate reductase, cytoplasmic YEL054C RPL12A 60S large subunit ribosomal protein L12.e YEL056W HAT2 subunit of the major yeast histone acetyltransferase YEL071W DLD3 D-lactate dehydrogenase YER002W NOP16 weak similarity to chicken microfibril-associated protein YER003C PMI40 mannose-6-phosphate isomerase YER008C SEC3 component of exocyst complex YER009W NTF2 nuclear transport factor YER023W PRO3 delta 1-pyrroline-5-carboxylate reductase YER025W GCD11 translation initiation factor eIF2 gamma chain YER056C-A RPL34A ribosomal protein L34 YER065C ICL1 isocitrate lyase YER074W RPS24A 40s small subunit ribosomal protein S24.e YER090W TRP2 anthranilate synthase component I YER091C MET6 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase YER102W RPS8B ribosomal protein S8.e YER103W SSA4 heat shock protein of HSP70 family, cytosolic YER107C GLE2 required for nuclear pore complex structure and function YER110C KAP123 RAN-binding protein YER117W RPL23B ribosomal protein L23.e YER131W RPS26B 40S small subunit ribosomal protein S26e-c5 YER133W GLC7 ser/thr phosphoprotein phosphatase 1, catalytic chain YER136W GDI1 GDP dissociation inhibitor YER151C UBP3 ubiquitin-specific proteinase YER155C BEM2 GTPase-activating protein YER165W PAB1 mRNA polyadenylate-binding protein YER168C CCA1 tRNA nucleotidyltransferase YFL001W DEG1 pseudouridine synthase YFL008W SMC1 chromosome segregation protein YFL022C FRS2 phenylalanine--tRNA ligase beta chain, cytosolic YFL045C SEC53 phosphomannomutase YFR009W GCN20 positive effector of GCN2P YFR013W IOC3 similarity to YOL017w YFR014C CMK1 Ca2+/calmodulin-dependent ser/thr protein kinase type I YFR015C GSY1 UDP glucose--starch glucosyltransferase, isoform 1 YFR032C-A RPL29 60S large subunit ribosomal protein YFR034C PHO4 transcription factor YFR053C HXK1 hexokinase I YGL009C LEU1 3-isopropylmalate dehydratase YGL017W ATE1 arginyl tRNA transferase YGL026C TRP5 tryptophan synthase YGL030W RPL30 60S large subunit ribosomal protein L30.e YGL031C RPL24A 60S large subunit ribosomal protein L24.e.A YGL040C HEM2 porphobilinogen synthase YGL049C TIF4632 mRNA cap-binding protein (eIF4F), 130K subunit YGL062W PYC1 pyruvate carboxylase 1 YGL076C RPL7A 60S large subunit ribosomal protein L7.e.A YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL103W RPL28 60S large subunit ribosomal protein L27a.e YGL105W ARC1 protein with specific affinity for G4 quadruplex nucleic acids YGL123W RPS2 40S small subunit ribosomal protein YGL131C YGL131C weak similarity to S.pombe hypothetical protein C3H1.12C YGL135W RPL1B 60S large subunit ribosomal protein YGL147C RPL9A ribosomal protein L9.e YGL148W ARO2 chorismate synthase YGL154C LYS5 L-aminoadipate-semialdehyde dehydrogenase, small subunit YGL155W CDC43 geranylgeranyltransferase beta subunit YGL173C KEM1 multifunctional nuclease YGL180W APG1 essential for autophagocytosis YGL189C RPS26A 40S small subunit ribosomal protein S26e.c7 YGL195W GCN1 translational activator YGL206C CHC1 clathrin heavy chain YGL212W VAM7 vacuolar morphogenesis protein YGL233W SEC15 vesicular traffic control protein YGL248W PDE1 low affinity 3',5'-cyclic-nucleotide phosphodiesterase YGL252C RTG2 retrograde regulation protein YGL253W HXK2 hexokinase II YGL256W ADH4 alcohol dehydrogenase IV YGR027C RPS25A ribosomal protein S25.e.c7 YGR034W RPL26B 60S large subunit ribosomal protein YGR061C ADE6 5'-phosphoribosylformyl glycinamidine synthetase YGR072W UPF3 nonsense-mediated mRNA decay protein YGR078C PAC10 GIM4 - Gim complex component YGR080W TWF1 twinfilin, an actin monomer sequestering protein YGR083C GCD2 translation initiation factor eIF2B, 71 kDa (delta) subunit YGR085C RPL11B ribosomal protein YGR087C PDC6 pyruvate decarboxylase 3 YGR088W CTT1 catalase T, cytosolic YGR094W VAS1 valyl-tRNA synthetase YGR118W RPS23A 40S small subunit ribosomal protein S23.e YGR120C SEC35 required for ER to golgi vesicle docking YGR147C NAT2 N-acetyltransferase for N-terminal methionine YGR148C RPL24B 60S large subunit ribosomal protein L24.e.B YGR162W TIF4631 mRNA cap-binding protein (eIF4F), 150K subunit YGR166W KRE11 beta-glucan synthesis-associated protein YGR167W CLC1 clathrin light chain YGR184C UBR1 ubiquitin-protein ligase YGR185C TYS1 tyrosyl-tRNA synthetase YGR192C TDH3 glyceraldehyde-3-phosphate dehydrogenase 3 YGR204W ADE3 C1-tetrahydrofolate synthase (trifunctional enzyme),cytoplasmic YGR214W RPS0A 40S ribosomal protein p40 homolog A YGR234W YHB1 flavohemoglobin YGR238C KEL2 involved in cell fusion and morphogenesis YGR240C PFK1 6-phosphofructokinase, alpha subunit YGR254W ENO1 enolase I (2-phosphoglycerate dehydratase) YGR261C APL6 AP-3 complex subunit, beta3-adaptin, 91 KD YGR264C MES1 methionyl-tRNA synthetase YGR292W MAL12 alpha-glucosidase of the MAL1 locus YHL001W RPL14B ribosomal protein YHL007C STE20 ser/thr protein kinase of the pheromone pathway YHL015W RPS20 ribosomal protein YHL033C RPL8A 60S large subunit ribosomal protein L7a.e.A YHR010W RPL27A 60S large subunit ribosomal protein L27.e YHR013C ARD1 protein N-acetyltransferase subunit YHR018C ARG4 arginosuccinate lyase YHR021C RPS27B ribosomal protein S27.e YHR053C CUP1-1 metallothionein YHR055C CUP1-2 metallothionein YHR077C NMD2 nonsense-mediated mRNA decay protein 2 YHR128W FUR1 uracil phosphoribosyltransferase YHR129C ARP1 centractin YHR141C RPL42B ribosomal protein L36a.e YHR158C KEL1 involved in cell fusion and morphology YHR174W ENO2 enolase II (2-phosphoglycerate dehydratase) YHR183W GND1 6-phosphogluconate dehydrogenase YHR193C EGD2 alpha subunit of the nascent polypeptide-associated complex YHR201C PPX1 exopolyphosphatase YHR203C RPS4B ribosomal protein S4.e.c8 YHR210C YHR210C strong similarity to UDP-glucose-4-epimerase YIL018W RPL2B 60S large subunit ribosomal protein L8.e YIL026C IRR1 essential protein YIL033C BCY1 cAMP dependent protein kinase, regulatory subunit YIL052C RPL34B ribosomal protein L34.e YIL066C RNR3 ribonucleotide reductase, repair inducible large subunit YIL068C SEC6 protein transport protein YIL069C RPS24B 40S small subunit ribosomal protein S24.e YIL078W THS1 threonyl tRNA synthetase, cytosolic YIL095W PRK1 serine/threonine protein kinase involved in regulation of actin cytoskeleton organization YIL107C PFK26 6-phosphofructose-2-kinase, isozyme 1 YIL133C RPL16A 60S large subunit ribosomal protein YIL142W CCT2 chaperonin of the TCP1 ring complex, cytosolic YIL148W RPL40A ubiquitin YIL167W SDL1 serine dehydratase YIR004W DJP1 DnaJ-like protein involved specifically in peroxisomal protein import YIR011C STS1 required for transport of RNA15P from the cytoplasm to the nucleus YIR012W SQT1 suppresses dominant-negative mutants of the ribosomal protein QSR1 YIR034C LYS1 saccharopine dehydrogenase YJL008C CCT8 component of chaperonin-containing T-complex YJL014W CCT3 chaperonin of the TCP1 ring complex, cytosolic YJL026W RNR2 ribonucleoside-diphosphate reductase, small subunit YJL031C BET4 geranylgeranyl transferase, alpha chain YJL052W TDH1 glyceraldehyde-3-phosphate dehydrogenase 1 YJL085W EXO70 70 kDa exocyst component protein YJL088W ARG3 ornithine carbamoyltransferase YJL095W BCK1 ser/thr protein kinase of the MEKK family YJL111W CCT7 component of chaperonin-containing T-complex YJL121C RPE1 D-ribulose-5-phosphate 3-epimerase YJL136C RPS21B 40S small subunit ribosomal protein S21.e YJL138C TIF2 translation initiation factor eIF4A YJL141C YAK1 ser/thr protein kinase YJL153C INO1 myo-inositol-1-phosphate synthase YJL155C FBP26 fructose-2,6-bisphosphatase YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJL164C TPK1 cAMP-dependent protein kinase 1, catalytic chain YJL167W ERG20 farnesyl-pyrophosphate synthetase YJL177W RPL17B 60s large subunit ribosomal protein L17.e YJL189W RPL39 60S large subunit ribosomal protein L39.e YJL190C RPS22A ribosomal protein S15a.e.c10 YJL191W RPS14B 40S small subunit ribosomal protein S14.e.B YJL194W CDC6 cell division control protein YJR007W SUI2 translation initiation factor eIF2, alpha chain YJR009C TDH2 glyceraldehyde-3-phosphate dehydrogenase 2 YJR023C YJR023C hypothetical protein YJR047C ANB1 translation initiation factor eIF5A.2 YJR057W CDC8 dTMP kinase YJR062C NTA1 amino-terminal amidase YJR064W CCT5 T-complex protein 1, epsilon subunit YJR094W-A RPL43B 60S large subunit ribosomal protein YJR099W YUH1 ubiquitin-specific protease YJR104C SOD1 copper-zinc superoxide dismutase YJR109C CPA2 arginine-specific carbamoylphosphate synthase, large chain YJR123W RPS5 ribosomal protein S5.e YJR145C RPS4A ribosomal protein S4.e.c10 YJR148W BAT2 branched chain amino acid aminotransferase, cytosolic YKL006W RPL14A ribosomal protein YKL010C UFD4 similarity to rat ubiquitin ligase Nedd4 YKL019W RAM2 protein farnesyltransferase, alpha subunit YKL024C URA6 uridine-monophosphate kinase YKL056C YKL056C strong similarity to human IgE-dependent histamine-releasing factor YKL060C FBA1 fructose-bisphosphate aldolase YKL062W MSN4 transcriptional activator YKL064W MNR2 overexpression overcomes manganese toxicity YKL067W YNK1 nucleoside diphosphate kinase YKL081W TEF4 translation elongation factor eEF1, gamma chain YKL104C GFA1 glucosamine--fructose-6-phosphate transaminase YKL122C SRP21 signal recognition particle subunit YKL127W PGM1 phosphoglucomutase, minor isoform YKL130C SHE2 required for mother cell-specific expression of HO YKL152C GPM1 phosphoglycerate mutase YKL156W RPS27A ribosomal protein S27.e YKL166C TPK3 cAMP-dependent protein kinase 3, catalytic chain YKL180W RPL17A ribosomal protein L17.e YKL182W FAS1 fatty-acyl-CoA synthase, beta chain YKL190W CNB1 calcineurin B, regulatory subunit YKL197C PEX1 peroxisomal assembly protein - peroxin YKL210W UBA1 E1-like (ubiquitin-activating) enzyme YKL211C TRP3 anthranilate synthase component II YKL216W URA1 dihydroorotate dehydrogenase YKR026C GCN3 translation initiation factor eIF2B, 34 KD, alpha subunit YKR057W RPS21A ribosomal protein S21.e YKR059W TIF1 translation initiation factor 4A YKR080W MTD1 methylenetetrahydrofolate dehydrogenase (NAD+) YKR084C HBS1 translation elongation factor eEF-1 alpha chain homolog YKR094C RPL40B ubiquitin YKR097W PCK1 phosphoenolpyruvate carboxykinase YLL009C COX17 interacts genetically with SCO1 and SCO2 in cytochrome oxidase assembly YLL018C DPS1 aspartyl-tRNA synthetase, cytosolic YLL026W HSP104 heat shock protein YLL039C UBI4 ubiquitin YLL045C RPL8B 60s large subunit ribosomal protein L7a.e.B YLR027C AAT2 aspartate aminotransferase, cytosolic YLR029C RPL15A 60s large subunit ribosomal protein L15.e.c12 YLR044C PDC1 pyruvate decarboxylase, isozyme 1 YLR048W RPS0B 40S ribosomal protein p40 homolog B YLR058C SHM2 serine hydroxymethyltransferase, cytoplasmic YLR060W FRS1 phenylalanyl-tRNA synthetase, alpha subunit, cytosolic YLR075W RPL10 60S large subunit ribosomal protein YLR079W SIC1 p40 inhibitor of CDC28P-Clb protein kinase complex YLR126C YLR126C weak similarity to P.aeruginosa anthranilate synthase component II YLR133W CKI1 choline kinase YLR134W PDC5 pyruvate decarboxylase, isozyme 2 YLR166C SEC10 required for exocytosis YLR167W RPS31 ubiquitin/40S small subunit ribosomal protein YLR174W IDP2 isocitrate dehydrogenase, cytosolic YLR185W RPL37A ribosomal protein L37.e YLR195C NMT1 N-myristoyltransferase YLR200W YKE2 Gim complex component YLR216C CPR6 member of the cyclophilin family YLR240W VPS34 phosphatidylinositol 3-kinase YLR244C MAP1 methionine aminopeptidase, isoform 1 YLR248W RCK2 Ca/calmodulin-dependent ser/thr protein kinase YLR249W YEF3 translation elongation factor eEF3 YLR258W GSY2 UDP-glucose--starch glucosyltransferase, isoform 2 YLR264W RPS28B 40S small subunit ribosomal protein S28.e.c12 YLR287C-A RPS30A 40S small subunit ribosomal protein YLR291C GCD7 translation initiation factor eIF2b, 43 kDa subunit YLR293C GSP1 GTP-binding protein of the ras superfamily YLR303W MET17 O-acetylhomoserine sulfhydrylase YLR304C ACO1 aconitate hydratase YLR313C SPH1 required for bipolar bud site selection YLR325C RPL38 60S large subunit ribosomal protein YLR333C RPS25B ribosomal protein S25.e.c12 YLR340W RPP0 acidic ribosomal protein L10.e YLR344W RPL26A 60S large subunit ribosomal protein YLR347C KAP95 karyopherin-beta YLR354C TAL1 transaldolase YLR367W RPS22B ribosomal protein S15a.e.c12 YLR377C FBP1 fructose-1,6-bisphosphatase YLR388W RPS29A ribosomal protein S29.e.A YLR396C VPS33 vacuolar sorting protein YLR406C RPL31B 60S large subunit ribosomal protein L31.e.c12 YLR433C CNA1 calcineurin B, catalytic subunit YLR438W CAR2 ornithine aminotransferase YLR441C RPS1A ribosomal protein S3a.e YLR448W RPL6B 60S large subunit ribosomal protein YML007W YAP1 transcriptional activator involved in oxidative stress response YML024W RPS17A ribosomal protein S17.e.A YML026C RPS18B ribosomal protein S18.e.c13 YML028W TSA1 thiol-specific antioxidant YML057W CMP2 calcineurin B, catalytic subunit YML062C MFT1 mitochondrial fusion target protein YML063W RPS1B ribosomal protein S3a.e YML073C RPL6A 60S large subunit ribosomal protein YML094W GIM5 Gim complex component YML097C VPS9 vacuolar sorting protein YML100W TSL1 alpha,alpha-trehalose-phosphate synthase, 123 KD subunit YML105C SEC65 signal recognition particle subunit YMR037C MSN2 stress responsive regulatory protein YMR038C LYS7 copper chaperone for superoxide dismutase SOD1P YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YMR079W SEC14 phosphatidylinositol(PI)/phosphatidylcholine(PC) transfer protein YMR080C NAM7 nonsense-mediated mRNA decay protein YMR105C PGM2 phosphoglucomutase, major isoform YMR116C ASC1 40S small subunit ribosomal protein YMR121C RPL15B 60S large subunit ribosomal protein L15.e.c13 YMR142C RPL13B 60S large subunit ribosomal protein YMR143W RPS16A ribosomal protein S16.e YMR146C TIF34 translation initiation factor eIF3, p39 subunit YMR174C PAI3 protease A (ysca) inhibitor IA3 YMR186W HSC82 heat shock protein YMR194W RPL36A 60S large subunit ribosomal protein YMR199W CLN1 cyclin, G1/S-specific YMR205C PFK2 6-phosphofructokinase, beta subunit YMR208W ERG12 mevalonate kinase YMR220W ERG8 phosphomevalonate kinase YMR230W RPS10B ribosomal protein YMR235C RNA1 GTPase activating protein YMR242C RPL20A 60s large subunit ribosomal protein YMR260C TIF11 translation initiation factor eIF1a YMR261C TPS3 alpha,alpha-trehalose-phosphate synthase, 115 KD subunit YMR303C ADH2 alcohol dehydrogenase II YMR309C NIP1 associated with 40s ribosomal subunit YNL007C SIS1 heat shock protein YNL015W PBI2 proteinase B inhibitor 2 YNL016W PUB1 major polyadenylated RNA-binding protein of nucleus and cytoplasm YNL062C GCD10 translation initiation factor eIF3 RNA-binding subunit YNL064C YDJ1 mitochondrial and ER import protein YNL067W RPL9B ribosomal protein L9.e.c14 YNL069C RPL16B 60S large subunit ribosomal protein YNL077W YNL077W similarity to dnaJ protein homolog YDJ1 YNL096C RPS7B strong similarity to ribosomal protein S7 YNL104C LEU4 2-isopropylmalalate synthase YNL126W SPC98 spindle pole body component YNL134C YNL134C similarity to C.carbonum toxD gene YNL135C FPR1 peptidyl-prolyl cis-trans isomerase, FK506-binding protein YNL153C GIM3 Gim complex component YNL162W RPL42A ribosomal protein L36a.e YNL178W RPS3 ribosomal protein S3.e YNL209W SSB2 heat shock protein of HSP70 family, cytosolic YNL223W AUT2 essential for autophagy YNL239W LAP3 member of the GAL regulon YNL241C ZWF1 glucose-6-phosphate dehydrogenase YNL244C SUI1 translation initiation factor 3 (eIF3) YNL259C ATX1 antioxidant protein and metal homeostasis factor YNL272C SEC2 protein transport protein YNL277W MET2 homoserine O-acetyltransferase YNL301C RPL18B 60S large subunit ribosomal protein L18.e YNL302C RPS19B 40S small subunit ribosomal protein S19.e YNL316C PHA2 prephenate dehydratase YNL329C PEX6 peroxisomal assembly protein YNR050C LYS9 saccharopine dehydrogenase (NADP+, L-glutamate forming) YOL016C CMK2 Ca2+/calmodulin-dependent ser/thr protein kinase, type II YOL039W RPP2A acidic ribosomal protein P2.beta YOL040C RPS15 40S small subunit ribosomal protein YOL058W ARG1 argininosuccinate synthetase YOL076W MDM20 necessary for mitochondrial inheritance and organisation of the actin cytoskeleton YOL086C ADH1 alcohol dehydrogenase I YOL097C WRS1 tryptophan--tRNA ligase YOL120C RPL18A 60S large subunit ribosomal protein S18.e YOL121C RPS19A 40S small subunit ribosomal protein S19.e YOL123W HRP1 CF Ib (RNA3' Cleavage factor Ib) YOL126C MDH2 malate dehydrogenase, cytoplasmic YOL127W RPL25 ribosomal protein L23a.e YOL139C CDC33 translation initiation factor eIF4E YOR014W RTS1 potential regulatory subunit of protein phosphatase 2A YOR063W RPL3 60S large subunit ribosomal protein L3.e YOR069W VPS5 involved in Golgi retention and vacuolar sorting YOR095C RKI1 D-ribose-5-phosphate ketol-isomerase YOR096W RPS7A ribosomal protein YOR101W RAS1 GTP-binding protein YOR120W GCY1 galactose-induced protein of aldo/keto reductase family YOR124C UBP2 ubiquitin-specific proteinase YOR133W EFT1 translation elongation factor eEF2 YOR160W MTR10 involved in nuclear protein import YOR167C RPS28A 40S small subunit ribosomal protein S28.e.c15 YOR168W GLN4 glutaminyl-tRNA synthetase YOR178C GAC1 ser/thr phosphoprotein phosphatase 1, regulatory chain YOR182C RPS30B ribosomal protein S30 YOR185C GSP2 GTP-binding protein of the RAS superfamily YOR202W HIS3 imidazoleglycerol-phosphate dehydratase YOR204W DED1 ATP-dependent RNA helicase YOR208W PTP2 protein-tyrosine-phosphatase YOR236W DFR1 dihydrofolate reductase YOR260W GCD1 translation initiation factor eIF2bgamma subunit YOR274W MOD5 tRNA isopentenyltransferase YOR276W CAF20 mRNA CAP-binding protein (eIF4F), 20K subunit YOR293W RPS10A ribosomal protein S10.e YOR302W YOR302W CPA1 leader peptide YOR303W CPA1 arginine-specific carbamoylphosphate synthase, small chain YOR312C RPL20B 60S large subunit ribosomal protein YOR335C ALA1 alanyl-tRNA synthetase, cytosolic YOR357C GRD19 involved in retrieval of late Golgi membrane proteins from the prevacuolar compartment YOR360C PDE2 high affinity 3',5'-cyclic-nucleotide phosphodiesterase YOR361C PRT1 translation initiation factor eIF3 subunit YOR369C RPS12 40S small subunit acidic ribosomal protein S12 YOR370C MRS6 geranylgeranyltransferase regulatory subunit YOR375C GDH1 glutamate dehydrogenase (NADP+) YPL001W HAT1 histone acetyltransferase subunit YPL028W ERG10 acetyl-CoA C-acetyltransferase, cytosolic YPL048W CAM1 translation elongation factor eEF1 gamma homologue YPL061W ALD6 aldehyde dehydrogenase, cytosolic YPL065W VPS28 involved in vacuolar traffic YPL079W RPL21B ribosomal protein L21 YPL081W RPS9A ribosomal protein S9.e.A YPL090C RPS6A ribosomal protein S6.e YPL106C SSE1 heat shock protein of HSP70 family YPL111W CAR1 arginase YPL117C IDI1 isopentenyl-diphosphate delta-isomerase YPL131W RPL5 60S large subunit ribosomal protein L5.e YPL143W RPL33A ribosomal protein L35a.e.c16 YPL145C KES1 involved in ergosterol biosynthesis YPL160W CDC60 leucine--tRNA ligase, cytosolic YPL198W RPL7B 60S large subunit ribosomal protein YPL210C SRP72 signal recognition particle protein YPL220W RPL1A ribosomal protein YPL231W FAS2 fatty-acyl-CoA synthase, alpha chain YPL237W SUI3 translation initiation factor eIF2 beta subunit YPL240C HSP82 heat shock protein YPL242C IQG1 involved in cytokinesis, has similarity to mammalian IQGAP proteins YPL243W SRP68 signal recognition particle protein YPL249C-A RPL36B 60S large subunit ribosomal protein YPL256C CLN2 cyclin, G1/S-specific YPL262W FUM1 fumarate hydratase YPR005C HAL1 salt-induced protein YPR016C TIF6 translation initiation factor 6 (eIF6) YPR032W SRO7 polarized exocytosis by regulating SNARE function YPR033C HTS1 histidine--tRNA ligase, mitochondrial YPR035W GLN1 glutamate--ammonia ligase YPR041W TIF5 translation initiation factor eIF5 YPR043W RPL43A ribosomal protein L37a.e YPR051W MAK3 N-acetyltransferase YPR055W SEC8 protein transport protein YPR060C ARO7 chorismate mutase YPR074C TKL1 transketolase 1 YPR080W TEF1 translation elongation factor eEF1 alpha-A chain, cytosolic YPR088C SRP54 signal recognition particle subunit YPR102C RPL11A ribosomal protein L11.e YPR132W RPS23B 40S small subunit ribosomal protein S23.e YPR145W ASN1 asparagine synthetase YPR160W GPH1 glycogen phosphorylase YPR163C TIF3 translation initiation factor eIF4B cytoskeleton (108 ORFs) 40.04 108 YAL020C ATS1 alpha-tubulin suppressor YAL029C MYO4 myosin heavy chain, unconventional (class V) isoform YBL007C SLA1 cytoskeleton assembly control protein YBL034C STU1 mitotic spindle protein YBL063W KIP1 kinesin-related protein YBR109C CMD1 calmodulin YBR130C SHE3 required for mother cell-specific expression of HO YBR133C HSL7 adapter in a regulatory pathway that relieves tyrosine phosphorylation of CDC28 YBR172C SMY2 kinesin-related protein YBR200W BEM1 bud emergence mediator YBR234C ARC40 ARP2/3 protein complex subunit, 40 kilodalton YCL014W BUD3 budding protein YCL024W KCC4 kinase coordinate cell cycle progression with the organization of the peripheralcytoskeleton YCL029C BIK1 nuclear fusion protein YCL034W LSB5 possible role in the regulation of actin cytoskeletal organization YCR002C CDC10 cell division control protein YCR009C RVS161 similarity to human amphiphysin and RVS167P YCR088W ABP1 actin-binding protein YDL029W ARP2 actin-like protein YDL178W AIP2 actin interacting protein 2 YDR085C AFR1 involved in morphogenesis of the mating projection YDR106W ARP10 similarity to Actin proteins YDR129C SAC6 actin filament bundling protein, fimbrin YDR164C SEC1 protein transport protein YDR218C SPR28 septin-related sporulation protein YDR309C GIC2 CDC42 GTPase-binding protein YDR356W NUF1 spindle pole body component YDR388W RVS167 reduced viability upon starvation protein YDR389W SAC7 suppressor of actin mutation YDR424C DYN2 dynein light chain 1, cytosolic YDR484W SAC2 suppressor of actin mutation YDR488C PAC11 required in the absence of CIN8P YEL061C CIN8 kinesin-related protein YER007W PAC2 involved in the stabilization of microtubles YER016W BIM1 binding to microtubules YFL009W CDC4 cell division control protein YFL037W TUB2 beta-tubulin YFL039C ACT1 actin YFR024C-A LSB3 possible role in the regulation of actin cytoskeletal organization YGL061C DUO1 essential mitotic spindle protein YGL216W KIP3 kinesin-related protein required for nuclear migration YGR059W SPR3 sporulation-specific septin YGR080W TWF1 twinfilin, an actin monomer sequestering protein YGR113W DAM1 essential mitotic spindle pole protein YGR245C SDA1 required for normal organization of the actin cytoskeleton; required for passage through Start YHR016C YSC84 strong similarity to hypothetical protein YFR024c-a YHR023W MYO1 myosin-1 isoform (type II myosin) heavy chain YHR107C CDC12 septin YIL034C CAP2 F-actin capping protein, beta subunit YIL062C ARC15 subunit of the ARP2/3 complex YIL138C TPM2 tropomyosin, isoform 2 YIL149C MLP2 involved in translocation of macromolecules between the nucleoplasm and the NPC YIL159W BNR1 regulator of budding YIR006C PAN1 actin-cytoskeleton assembly protein YJL042W MHP1 microtubule-associated protein YJR065C ARP3 actin related protein YJR076C CDC11 septin YJR125C ENT3 cytoskeletal adaptor YKL007W CAP1 F-actin capping protein alpha subunit YKL013C ARC19 subunit of the ARP2/3 complex YKL022C CDC16 subunit of anaphase-promoting complex (cyclosome) YKL079W SMY1 kinesin-related protein YKL129C MYO3 myosin type I YLL021W SPA2 involved in cell polarity YLL050C COF1 cofilin, actin binding and severing protein YLR085C ARP6 Actin-related protein YLR314C CDC3 cell division control protein YLR319C BUD6 bud site selection protein YLR337C VRP1 verprolin YLR370C ARC18 subunit of the ARP2/3 complex YLR429W CRN1 a coronin, that promotes actin polymerization and crosslinking to microtubules YML085C TUB1 alpha-1 tubulin YML104C MDM1 intermediate filament protein YML124C TUB3 alpha-3 tubulin YMR032W HOF1 involved in cytokinesis YMR033W ARP9 Actin-related protein YMR092C AIP1 actin cytoskeleton component YMR109W MYO5 myosin I YMR138W CIN4 GTP-binding protein YNL059C ARP5 Actin-related protein YNL079C TPM1 tropomyosin 1 YNL084C END3 required for endocytosis and cytoskeletal organization YNL138W SRV2 adenylate cyclase-associated protein, 70kDa YNL148C ALF1 similarity to human tubulin folding cofactor B YNL233W BNI4 bud neck involved YNL243W SLA2 cytoskeleton assembly control protein YNL271C BNI1 regulator of budding YNR035C ARC35 subunit of the ARP2/3 complex YOL145C CTR9 required for G1 cyclin expression YOR058C ASE1 microtubule-associated protein (nonmotor) YOR122C PFY1 profilin YOR134W BAG7 structural homolog of SAC7P YOR141C ARP8 Actin-related protein YOR156C NFI1 interacts with CDC12P in 2-hybrid assay YOR181W LAS17 component of actin cortical patches YOR239W-A ABP140 actin filament-binding protein YOR265W RBL2 beta-tubulin binding protein YOR272W YTM1 microtubule-interacting protein YOR326W MYO2 myosin heavy chain YOR349W CIN1 chromosome segregation protein YOR362C PRE10 20S proteasome subunit C1 (alpha7) YPL105C YPL105C similarity to SMY2P YPL155C KIP2 kinesin-related protein YPL174C NIP100 component of the dynactin complex YPL241C CIN2 involved in chromosome segregation YPL269W KAR9 cortical protein required for cytoplasmic microtubule orientation and nuclear migration YPR034W ARP7 component of SWI-SNF global transcription activator complex and RSC chromatin remodeling complex YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins centrosome (31 ORFs) 40.05 31 YAL034W-A MTW1 determining metaphase spindle length YBR109C CMD1 calmodulin YBR211C AME1 actin related protein YCL029C BIK1 nuclear fusion protein YDR201W SPC19 spindle pole body protein YER018C SPC25 spindle pole body protein YGL075C MPS2 Protein of the nuclear envelope/endoplasmic reticulum required for spindle pole body assembly and normal chromosome segregation YGL093W SPC105 spindle pole body protein YHR172W SPC97 spindle pole body component YIL144W TID3 DMC1P interacting protein YJL041W NSP1 nuclear pore protein YKL042W SPC42 spindle pole body component YKR037C SPC34 spindle pole body protein YKR054C DYN1 dynein heavy chain, cytosolic YLR045C STU2 suppressor of a cs tubulin mutation YLR212C TUB4 gamma tubulin YMR065W KAR5 nuclear fusion protein YMR117C SPC24 spindle pole body protein YMR198W CIK1 spindle pole body associated protein YMR294W JNM1 mitosis protein, involved in nuclear migration YNL126W SPC98 spindle pole body component YNL188W KAR1 cell division control protein YNL225C CNM67 involved in cytokinesis YOL069W NUF2 spindle pole body protein YOR177C MPC54 meiosis-specific component of the SPB YOR257W CDC31 spindle pole body component, centrin YOR373W NUD1 cell cycle regulatory protein YPL124W NIP29 nuclear import protein YPL174C NIP100 component of the dynactin complex YPL255W BBP1 cell division control protein YPR141C KAR3 kinesin-related protein endoplasmic reticulum (157 ORFs) 40.07 157 YAL009W SPO7 meiotic protein YAL023C PMT2 mannosyltransferase YAL042W ERV46 component of copii vesicles involved in transport between the ER and golgi complex YAL058W CNE1 calnexin, involved in regulation of secretion YBL040C ERD2 ER lumen protein-retaining receptor YBL041W PRE7 20S proteasome subunit(beta6) YBL082C RHK1 mannosyltransferase YBR029C CDS1 CDP-diacylglycerol synthase YBR036C CSG2 calcium dependent regulatory protein YBR110W ALG1 beta-mannosyltransferase YBR171W SEC66 ER protein-translocation complex subunit YBR173C UMP1 proteasome maturation factor YBR201W DER1 involved in degradation proteins in the ER YBR229C ROT2 glucosidase II, catalytic subunit YBR243C ALG7 UDP-N-acetylglucosamine-1-phosphate transferase YBR265W TSC10 3-ketosphinganine reductase YBR283C SSH1 involved in co-translational pathway of protein transport YBR290W BSD2 metal homeostasis protein YCL001W RER1 required for correct localization of SEC12P YCL043C PDI1 protein disulfide-isomerase precursor YCL052C PBN1 required for post-translational processing of the protease B precursor PRB1P YCR067C SED4 protein of the endoplasmic reticulum YCR069W SCC3 peptidyl-prolyl cis-trans isomerase precursor YCR075C ERS1 intracellular protein transport protein YDL007W RPT2 26S proteasome regulatory subunit YDL020C RPN4 26S proteasome subunit YDL095W PMT1 mannosyltransferase YDL097C RPN6 subunit of the regulatory particle of the proteasome YDL147W RPN5 subunit of the regulatory particle of the proteasome YDL212W SHR3 endoplasmatic reticulum membrane protein YDL232W OST4 oligosaccharyltransferase subunit YDR040C ENA1 P-type ATPase involved in Na+ and Li+ efflux YDR057W YDR057W weak similarity to L.lactis mleR protein YDR069C DOA4 ubiquitin-specific protease YDR086C SSS1 ER protein-translocase complex subunit YDR245W MNN10 subunit of mannosyltransferase complex YDR292C SRP101 signal recognition particle receptor, alpha chain YDR297W SUR2 required for the hydroxylation of C-4 of the sphingoid moiety of ceramide YDR304C CYP5 peptidyl-prolyl cis-trans isomerase D precursor(cyclophilin D) of the ER YDR331W GPI8 essential for GPI anchor attachment YDR394W RPT3 26S proteasome regulatory subunit YDR410C STE14 farnesyl cysteine carboxyl-methyltransferase YDR414C ERD1 required for retention of luminal ER proteins YDR427W RPN9 subunit of the regulatory particle of the proteasome YDR498C SEC20 secretory pathway protein YDR518W EUG1 protein disulfide isomerase YDR519W FKB2 FK506/rapamycin-binding protein of the ER YEL002C WBP1 oligosaccharyl transferase beta subunit precursor YER012W PRE1 20S proteasome subunit C11(beta4) YER021W RPN3 26S proteasome regulatory subunit YER026C CHO1 CDP-diacylglycerol serine O-phosphatidyltransferase YER087C-B SBH1 involved in translocation into the ER YER094C PUP3 20S proteasome subunit (beta3) YER100W UBC6 E2 ubiquitin-conjugating enzyme YER120W SCS2 required for inositol metabolism YFL025C BST1 negative regulator of COPII vesicle formation YFL048C EMP47 Golgi membrane protein YFR004W RPN11 26S proteasome regulatory subunit YFR050C PRE4 20S proteasome subunit(beta7) YFR052W RPN12 26S proteasome regulatory subunit YGL011C SCL1 20S proteasome subunit YC7ALPHA/Y8 (alpha1) YGL022W STT3 oligosaccharyl transferase subunit YGL027C CWH41 ER glucosidase I YGL048C RPT6 26S proteasome regulatory subunit YGL055W OLE1 stearoyl-CoA desaturase YGL145W TIP20 required for ER to Golgi transport YGL226C-A OST5 subunit of N-oligosaccharyltransferase, zeta subunit YGR060W ERG25 C-4 sterol methyl oxidase YGR105W VMA21 ATPase assembly integral membrane protein YGR135W PRE9 20S proteasome subunit Y13 (alpha3) YGR157W CHO2 phosphatidylethanolamine N-methyltransferase YGR175C ERG1 squalene monooxygenase YGR202C PCT1 cholinephosphate cytidylyltransferase YGR216C GPI1 required for N-acetylglucosaminyl phosphatidylinositol synthesis YGR232W NAS6 possible homolog of human 26S proteasome regulatory subunit p28 YGR253C PUP2 20S proteasome subunit(alpha5) YGR270W YTA7 26S proteasome subunit YHR004C NEM1 required for nuclear morphology YHR007C ERG11 cytochrome P450 lanosterol 14a-demethylase YHR027C RPN1 26S proteasome regulatory subunit YHR042W NCP1 NADPH-cytochrome P450 reductase YHR057C CYP2 peptidyl-prolyl cis-trans isomerase YHR060W VMA22 vacuolar ATPase assembly protein YHR072W ERG7 lanosterol synthase YHR079C IRE1 protein kinase YHR123W EPT1 sn-1,2-diacylglycerol ethanolamine- and cholinephosphotransferase YHR142W CHS7 control of protein export from the ER (like chitin synthase III) YHR190W ERG9 farnesyl-diphosphate farnesyltransferase YHR200W RPN10 26S proteasome regulatory subunit YIL075C RPN2 26S proteasome regulatory subunit YIL109C SEC24 component of COPII coat of ER-Golgi vesicles YIR022W SEC11 signal sequence processing protein YJL001W PRE3 20S proteasome subunit (beta1) YJL002C OST1 oligosaccharyltransferase, alpha subunit YJL034W KAR2 nuclear fusion protein YJL073W JEM1 similarity to heat shock proteins YJL080C SCP160 required for maintenance of exact ploidy YJR010C-A SPC1 signal peptidase 10.8 kDa subunit YJR073C OPI3 methylene-fatty-acyl-phospholipid synthase YJR117W STE24 zinc metallo-protease YJR131W MNS1 alpha1,2-mannosidase YJR143C PMT4 dolichyl-phosphate-mannose--protein O-mannosyl transferase YKL065C YET1 Yeast endoplasmic reticulum 25 kDa transmembrane protein YKL073W LHS1 chaperone of the ER lumen YKL119C VPH2 H+-ATPase assembly protein YKL145W RPT1 26S proteasome regulatory subunit YKL154W SRP102 signal recognition particle receptor, beta chain YKL212W SAC1 recessive suppressor of secretory defect YLR056W ERG3 C-5 sterol desaturase YLR066W SPC3 signal peptidase subunit YLR078C BOS1 secretory pathway protein YLR088W GAA1 required for attachment of GPI anchor onto proteins YLR292C SEC72 ER protein-translocation complex subunit YLR378C SEC61 ER protein-translocation complex subunit YLR450W HMG2 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 YML055W SPC2 signal peptidase 18 KD subunit YML075C HMG1 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 YML092C PRE8 20S proteasome subunit Y7 (alpha2) YML130C ERO1 required for protein disulfide bond formation in the ER YMR013C SEC59 dolichol kinase YMR015C ERG5 C-22 sterol desaturase YMR022W QRI8 E2 ubiquitin-conjugation enzyme YMR065W KAR5 nuclear fusion protein YMR149W SWP1 oligosaccharyltransferase delta subunit YMR202W ERG2 C-8 sterol isomerase YMR214W SCJ1 homolog of E. coli DnaJ, functions in the endoplasmic reticulum by interaction with KAR2P YMR314W PRE5 20S proteasome subunit(alpha6) YNL064C YDJ1 mitochondrial and ER import protein YNL130C CPT1 diacylglycerol cholinephosphotransferase YNR016C ACC1 acetyl-CoA carboxylase YNR026C SEC12 GDP/GTP exchange factor for SAR1P YOL013C HRD1 involved in degradation of HMG2P YOL031C YOL031C weak similarity to Y.lipolytica SLS1 protein precursor YOL038W PRE6 20S proteasome subunit (alpha4) YOL088C MPD2 protein disulfide isomerase-related protein YOR067C ALG8 glucosyltransferase YOR075W UFE1 syntaxin (T-SNARE) of the ER YOR085W OST3 oligosaccharyltransferase gamma subunit YOR103C OST2 oligosaccharyltransferase epsilon subunit YOR117W RPT5 26S proteasome regulatory subunit YOR157C PUP1 20S proteasome subunit (beta2) YOR254C SEC63 ER protein-translocation complex subunit YOR259C RPT4 26S proteasome regulatory subunit YOR261C RPN8 26S proteasome regulatory subunit YOR288C MPD1 disulfide isomerase related protein YOR321W PMT3 mannosyltransferase YOR336W KRE5 killer toxin-resistance protein YOR370C MRS6 geranylgeranyltransferase regulatory subunit YPL076W GPI2 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein YPL085W SEC16 multidomain vesicle coat protein YPL094C SEC62 ER protein-translocation complex subunit YPL175W SPT14 N-acetylglucosaminyltransferase YPL227C ALG5 dolichol-P-glucose synthetase YPR103W PRE2 20S proteasome subunit (beta5) YPR108W RPN7 subunit of the regulatory particle of the proteasome YPR113W PIS1 CDP diacylglycerol--inositol 3-phosphatidyltransferase YPR183W DPM1 dolichyl-phosphate beta-D-mannosyltransferase Golgi (82 ORFs) 40.08 82 YAL026C DRS2 P-type amino-phospholipids-ATPase YAL042W ERV46 component of copii vesicles involved in transport between the ER and golgi complex YBL017C PEP1 vacuolar protein sorting/targeting protein YBL040C ERD2 ER lumen protein-retaining receptor YBL102W SFT2 suppressor of SED5 ts mutants YBR079C RPG1 translation initiation factor eIF3 (p110 subunit) YBR097W VPS15 ser/thr protein kinase YBR254C TRS20 TRAPP subunit of 20 kDa involved in targeting and fusion of ER to golgi transport vesicles YCL001W RER1 required for correct localization of SEC12P YDL137W ARF2 GTP-binding protein of the ARF family YDL192W ARF1 small GTP-binding protein of the ARF family YDR027C LUV1 interacts with the beta-tubulin binding protein RBL2P YDR108W GSG1 sporulation specific protein YDR170C SEC7 component of non-clathrin vesicle coat YDR189W SLY1 hydrophilic suppressor of YPT1 and member of the SEC1P family YDR246W TRS23 TRAPP subunit of 20 kDa involved in targeting and fusion of ER to golgi transport vesicles YDR270W CCC2 probable copper-transporting ATPase YDR358W GGA1 Arf-binding protein; involved in trafficking of proteins YDR407C TRS120 TRAPP subunit of 120 kDa involved in targeting and fusion of ER to golgi transport vesicles YDR468C TLG1 member of the syntaxin family of t-SNAREs YDR472W TRS31 TRAPP subunit of 31 kDa involved in targeting and fusion of ER to golgi transport vesicles YDR483W KRE2 alpha-1,2-mannosyltransferase YDR484W SAC2 suppressor of actin mutation YDR517W GRH1 Yeast (GR)ASP65 (H)omologue YEL004W YEA4 strong similarity to K.lactis golgi uridine diphosphate-N-acetylglucosamine transporter YEL022W GEA2 GDP/GTP exchange factor for ARF YEL036C ANP1 required for protein glycosylation in the golgi YEL042W GDA1 guanosine diphosphatase YER001W MNN1 alpha-1,3-mannosyltransferase YER031C YPT31 GTP-binding protein of the rab family YER123W YCK3 casein kinase, isoform 3 YER157W SEC34 required for vesicle tethering to the yeast Golgi apparatus YFL038C YPT1 GTP-binding protein of the rab family YFL048C EMP47 Golgi membrane protein YGL038C OCH1 alpha-1,6-mannosyltransferase YGL054C ERV14 ER-derived Vesicles YGL167C PMR1 Ca2+-transporting P-type ATPase YGL203C KEX1 carboxypeptidase (YSC-alpha) YGL225W GOG5 GDP-mannose transporter into the lumen of the Golgi YGR143W SKN1 glucan synthase subunit YGR166W KRE11 beta-glucan synthesis-associated protein YGR170W PSD2 phosphatidylserine decarboxylase 2 YGR172C YIP1 golgi membrane protein YHL031C GOS1 SNARE protein of Golgi compartment YHR012W VPS29 involved in vacuolar protein sorting YIL109C SEC24 component of COPII coat of ER-Golgi vesicles YJL029C VPS53 subunit of VP52-54 complex, required for protein sorting at the yeast late Golgi YJL139C YUR1 mannosyltransferase YJL154C VPS35 protein-sorting protein, vacuolar YJR031C GEA1 GDP/GTP exchange factor for ARF YJR075W HOC1 suppressor of PKC1 YKL006C-A SFT1 SNARE-like protein YKL196C YKT6 SNARE protein for Endoplasmic Reticulum-Golgi transport YKL212W SAC1 recessive suppressor of secretory defect YKR001C VPS1 member of the dynamin family of GTPases YKR061W KTR2 mannosyltransferase YKR068C BET3 involved in targeting and fusion of ER to golgi transport vesicles YLR026C SED5 syntaxin (T-SNARE) YLR034C SMF3 strong similarity to SMF2 protein and S.pombe hypothetical protein YLR220W CCC1 involved in calcium regulation YLR240W VPS34 phosphatidylinositol 3-kinase YLR262C YPT6 GTP-binding protein of the rab family YLR330W CHS5 chitin synthesis protein YML077W BET5 involved in targeting and fusion of ER to golgi transport vesicles YML115C VAN1 vanadate resistance protein YMR004W MVP1 required for vacuolar protein sorting YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YMR218C TRS130 TRAPP subunit of 130 kDa involved in targeting and fusion of ER to golgi transport vesicles YMR272C SCS7 required for hydroxylation of ceramide YNL090W RHO2 GTP-binding protein of the RHO subfamily of RAS-like proteins YNL130C CPT1 diacylglycerol cholinephosphotransferase YNL238W KEX2 endoproteinase of late golgi compartment YOR079C ATX2 multicopy suppressor of SOD-linked defects YOR099W KTR1 mannosyltransferase involved in n-linked and o-linked glycosylation YOR115C TRS33 TRAPP subunit of 33 kDa involved in targeting and fusion of ER to golgi transport vesicles YOR216C RUD3 suppressor of USO1-1 transport defect YOR219C STE13 type IV dipeptidyl aminopeptidase YOR370C MRS6 geranylgeranyltransferase regulatory subunit YPL050C MNN9 required for complex N-glycosylation YPR113W PIS1 CDP diacylglycerol--inositol 3-phosphatidyltransferase YPR159W KRE6 glucan synthase subunit YPR165W RHO1 GTP-binding protein of the rho subfamily of ras-like proteins intracellular transport vesicles (42 ORFs) 40.09 42 YAL030W SNC1 synaptic vesicle-associated membrane protein YBL037W APL3 AP-2 complex subunit, alpha-adaptin, 113 KD YBL050W SEC17 transport vesicle fusion protein YBR079C RPG1 translation initiation factor eIF3 (p110 subunit) YBR080C SEC18 vesicular-fusion protein, functional homolog of NSF YBR097W VPS15 ser/thr protein kinase YBR105C VID24 required for vacuolar import and degradation of FBP1P YDL137W ARF2 GTP-binding protein of the ARF family YDL145C COP1 coatomer complex alpha chain of secretory pathway vesicles YDL195W SEC31 component of the COPII coat of ER-golgi vesicles YDR170C SEC7 component of non-clathrin vesicle coat YDR238C SEC26 coatomer complex beta chain of secretory pathway vesicles YFL005W SEC4 GTP-binding protein of the ras superfamily YFR051C RET2 coatomer complex delta chain YGL137W SEC27 coatomer complex beta' chain (beta'-cop) of secretory pathway vesicles YGL200C EMP24 component of the COPII-coated vesicles, 24 kDa YIL004C BET1 protein transport protein YIL076W SEC28 epsilon-COP coatomer subunit YIL109C SEC24 component of COPII coat of ER-Golgi vesicles YJR005W APL1 AP-2 complex subunit, beta2-adaptin, 78 KD YJR058C APS2 AP-2 complex subunit, sigma2 subunit, 17 KD YKL135C APL2 AP-1 complex subunit, beta1-adaptin, 82 KD YLR078C BOS1 secretory pathway protein YLR170C APS1 AP-1 complex subunit, sigma1 subunit, 18 KD YLR208W SEC13 protein transport protein YLR240W VPS34 phosphatidylinositol 3-kinase YLR268W SEC22 synaptobrevin (V-SNARE) YML001W YPT7 GTP-binding protein of the RAB family YML012W ERV25 component of the COPII-coated vesicles, 25 Kda YMR197C VTI1 v-SNARE: involved in Golgi retrograde protein traffic YNL272C SEC2 protein transport protein YNL287W SEC21 coatomer complex gamma chain (gamma-COP) of secretory pathway vesicles YNR049C MSO1 secretion protein, multicopy suppressor of SEC1 YOL062C APM4 AP-2 complex subunit, mu2 subunit, 55 KD YOR089C VPS21 GTP-binding protein YOR327C SNC2 synaptobrevin (v-SNARE) homolog present on post-Golgi vesicles YPL010W RET3 coatomer complex zeta chain YPL085W SEC16 multidomain vesicle coat protein YPL218W SAR1 GTP-binding protein of the ARF family YPL259C APM1 AP-1 complex subunit, mu1 subunit, 54 KD YPR017C DSS4 GDP/GTP exchange factor for SEC4P YPR181C SEC23 component of COPII coat of ER-golgi vesicles nucleus (774 ORFs) 40.10 774 YAL001C TFC3 TFIIIC (transcription initiation factor) subunit, 138 kD YAL009W SPO7 meiotic protein YAL019W FUN30 similarity to helicases of the SNF2/RAD54 family YAL021C CCR4 transcriptional regulator YAL025C MAK16 nuclear viral propagation protein YAL033W POP5 required for processing of tRNAs and rRNAs YAL041W CDC24 GTP/GDP exchange factor for CDC42P YAL043C PTA1 pre-tRNA processing protein / PF I subunit YAL051W OAF1 peroxisome proliferating transcription factor YAR007C RFA1 DNA replication factor A, 69 KD subunit YAR008W SEN34 tRNA splicing endonuclease gamma subunit YBL002W HTB2 histone H2B.2 YBL003C HTA2 histone H2A.2 YBL005W PDR3 pleiotropic drug resistance regulatory protein YBL008W HIR1 histone transcription regulator YBL014C RRN6 RNA polymerase I specific transcription initiation factor YBL018C POP8 required for processing of tRNAs and rRNAs YBL020W RFT1 nuclear division protein YBL021C HAP3 CCAAT-binding factor subunit YBL023C MCM2 member of the MCM2P,MCM3P,CDC46P family YBL024W NCL1 tRNA (cytosine-5-)-methyltransferase YBL025W RRN10 RNA polymerase I-specific transcription initiation factor YBL026W LSM2 Sm-like (Lsm) protein YBL035C POL12 DNA-directed DNA polymerase alpha, 70 KD subunit YBL041W PRE7 20S proteasome subunit(beta6) YBL054W YBL054W weak similarity to transforming protein (B-myb) YBL063W KIP1 kinesin-related protein YBL066C SEF1 putative transcription factor YBL074C AAR2 A1 cistron splicing factor YBL079W NUP170 nuclear pore protein YBL084C CDC27 subunit of anaphase-promoting complex (cyclosome) YBL093C ROX3 transcription factor YBL103C RTG3 bHLH/zip transcription factor that regulates CIT2 gene expression YBR009C HHF1 histone H4 YBR010W HHT1 histone H3 YBR026C (MRF1) mitochondrial respiratory function protein YBR034C HMT1 hnRNP arginine N-methyltransferase YBR049C REB1 transcription factor YBR055C PRP6 snRNP(U4/U6)-associated splicing factor YBR060C ORC2 origin recognition complex, 72 kDa subunit YBR072W HSP26 heat shock protein YBR081C SPT7 involved in alteration of transcription start site selection YBR083W TEC1 Ty transcription activator YBR087W RFC5 DNA replication factor C, 40 KD subunit YBR088C POL30 Proliferating Cell Nuclear Antigen (PCNA) YBR089C-A NHP6B nonhistone chromosomal protein YBR103W SIF2 SIR4P interacting protein YBR112C CYC8 general repressor of transcription YBR114W RAD16 nucleotide excision repair protein YBR119W MUD1 U1 snRNP-specific A protein YBR123C TFC1 TFIIIC (transcription initiation factor) subunit, 95 kD YBR142W MAK5 ATP-dependent RNA helicase YBR150C TBS1 weak similarity to transcription factors YBR154C RPB5 DNA-directed RNA polymerase I, II, III 25 KD subunit YBR158W CST13 weak similarity to TRCDSEMBL:AF176518_1 F-box protein FBL2; human YBR167C POP7 nuclear RNase P subunit YBR173C UMP1 proteasome maturation factor YBR182C SMP1 MADS-box transcription factor YBR186W PCH2 putative ATPase YBR193C MED8 transcriptional regulation mediator YBR198C TAF90 TFIID and SAGA subunit YBR202W CDC47 cell division control protein YBR236C ABD1 mRNA cap methyltransferase YBR237W PRP5 pre-mRNA processing RNA-helicase YBR239C YBR239C weak similarity to transcription factor PUT3P YBR240C THI2 regulator of the thiamine biosynthetic genes YBR247C ENP1 effects N-glycosylation YBR253W SRB6 DNA-directed RNA polymerase II suppressor protein YBR257W POP4 involved in processing of tRNAs and rRNAs YBR275C RIF1 RAP1-interacting factor 1 YBR278W DPB3 DNA-directed DNA polymerase epsilon, subunit C YBR279W PAF1 DNA-directed RNA polymerase II regulator YBR289W SNF5 component of SWI/SNF transcription activator complex YBR297W MAL33 maltose fermentation regulatory protein YCL011C GBP2 potential telomere-associated protein YCL017C NFS1 regulates Iron-Sulfur cluster proteins, cellular Iron uptake, andIron distribution YCL029C BIK1 nuclear fusion protein YCL054W SPB1 required for ribosome synthesis, putative methylase YCL055W KAR4 regulatory protein required for pheromone induction of karyogamy genes YCL059C KRR1 required for 40S ribosome biogenesis YCL066W HMLALPHA1 mating type regulatory protein, silenced copy at HML YCL067C HMLALPHA2 mating type regulatory protein, silenced copy at HML YCR014C POL4 DNA polymerase YCR018C SRD1 nucleolar protein YCR039C MATALPHA2 mating type regulatory protein, expressed copy at MAT locus YCR040W MATALPHA1 mating type regulatory protein, expressed copy at MAT locus YCR042C TSM1 component of TFIID complex YCR052W RSC6 subunit of the RSC complex YCR065W HCM1 transcription factor YCR066W RAD18 DNA repair protein YCR072C YCR072C strong similarity to S. pombe trp-asp repeat containing protein YCR081W SRB8 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YCR084C TUP1 general transcription repressor YCR092C MSH3 DNA mismatch repair protein YCR093W CDC39 nuclear protein YCR096C A2 mating type regulatory protein, silenced copy at HMR locus YCR097W A1 mating type regulatory protein, silenced copy at HMR locus YCR106W YCR106W similarity to transcription factor YDL003W MCD1 Mitotic Chromosome Determinant YDL005C MED2 transcriptional regulation mediator YDL007W RPT2 26S proteasome regulatory subunit YDL008W APC11 subunit of the anaphase promoting complex YDL014W NOP1 fibrillarin YDL017W CDC7 protein kinase YDL020C RPN4 26S proteasome subunit YDL029W ARP2 actin-like protein YDL030W PRP9 pre-mRNA splicing factor (snRNA-associated protein) YDL042C SIR2 silencing regulatory protein and DNA-repair protein YDL043C PRP11 pre-mRNA splicing factor YDL056W MBP1 transcription factor, subunit of the MBF factor YDL059C RAD59 recombination and DNA repair protein YDL064W UBC9 E2 ubiquitin-conjugating enzyme YDL097C RPN6 subunit of the regulatory particle of the proteasome YDL101C DUN1 protein kinase YDL102W CDC2 DNA-directed DNA polymerase delta, catalytic 125 KD subunit YDL106C PHO2 homeodomain protein YDL108W KIN28 cyclin-dependent ser/thr protein kinase YDL116W NUP84 nuclear pore protein YDL131W LYS21 homocitrate synthase YDL140C RPO21 DNA-directed RNA polymerase II, 215 KD subunit YDL147W RPN5 subunit of the regulatory particle of the proteasome YDL150W RPC53 DNA-directed RNA polymerase III, 47 KD subunit YDL153C SAS10 involved in silencing YDL154W MSH5 meiosis-specific protein YDL160C DHH1 putative RNA helicase of the DEAD box family YDL164C CDC9 DNA ligase YDL165W CDC36 transcription factor YDL170W UGA3 transcriptional activator for GABA catabolic genes YDL182W LYS20 homocitrate synthase YDL200C MGT1 O6-methylguanine DNA repair methyltransferase YDL207W GLE1 RNA export mediator YDL208W NHP2 nucleolar rRNA processing protein YDL220C CDC13 cell division control protein YDL226C GCS1 ADP-ribosylation factor GTPase-activating protein (ARF-GAP) YDL227C HO homothallic switching endonuclease YDR004W RAD57 DNA repair protein YDR006C SOK1 high copy suppressor of a cyclic AMP-dependent protein kinase mutant YDR021W FAL1 involved in maturation of 18S rRNA YDR028C REG1 regulatory subunit for protein phosphatase GLC7P YDR034C LYS14 transcriptional activator of lysine pathway genes YDR052C DBF4 regulatory subunit for CDC7P protein kinase YDR054C CDC34 E2 ubiquitin-conjugating enzyme YDR069C DOA4 ubiquitin-specific protease YDR073W SNF11 component of SWI/SNF transcription activator complex YDR076W RAD55 DNA repair protein YDR082W STN1 involved in telomere length regulation YDR088C SLU7 pre-mRNA splicing factor affecting 3' splice site choice YDR097C MSH6 DNA mismatch repair protein YDR113C PDS1 cell cycle regulator YDR118W APC4 subunit of the anaphase promoting complex YDR123C INO2 basic helix-loop-helix (BHLH) transcription factor YDR138W HPR1 hyperrecombination protein related to TOP1P YDR146C SWI5 transcription factor YDR156W RPA14 DNA-directed RNA polymerase I, A14 subunit YDR159W SAC3 leucine permease transcriptional regulator YDR167W TAF25 TFIID and SAGA subunit YDR173C ARG82 arginine metabolism transcription factor YDR174W HMO1 Non-histone protein YDR176W NGG1 general transcriptional adaptor or co-activator YDR180W SCC2 involved in sister chromatid cohesion YDR190C RVB1 RUVB-like protein YDR192C NUP42 nuclear pore protein YDR195W REF2 RNA 3'-end formation protein YDR207C UME6 negative transcriptional regulator YDR216W ADR1 zinc-finger transcription factor YDR217C RAD9 DNA repair checkpoint protein YDR224C HTB1 histone H2B YDR225W HTA1 histone H2A YDR227W SIR4 silencing regulatory and DNA-repair protein YDR228C PCF11 component of pre-mRNA 3'-end processing factor CF I YDR235W PRP42 U1 snRNP associated protein, required for pre-mRNA splicing YDR240C SNU56 U1 snRNA protein, no counterpart in mammalian snRNP YDR243C PRP28 pre-mRNA splicing factor RNA helicase of DEAD box family YDR254W CHL4 chromosome segregation protein YDR257C RMS1 regulatory protein YDR259C YAP6 transcription factor, of a fungal-specific family of bzip proteins YDR285W ZIP1 synaptonemal complex protein YDR301W CFT1 pre-mRNA 3'-end processing factor CF II YDR308C SRB7 DNA-directed RNA polymerase II holoenzyme and kornberg's mediator (SRB) subcomplex subunit YDR310C SUM1 suppressor of SIR mutations YDR311W TFB1 TFIIH subunit (transcription initiation factor), 75 kD YDR318W MCM21 involved in minichromosome maintenance YDR328C SKP1 kinetochore protein complex CBF3, subunit D YDR362C TFC6 TFIIIC (transcription initiation factor) subunit, 91 kD YDR364C CDC40 cell division control protein YDR369C XRS2 DNA repair protein YDR381W YRA1 RNA annealing protein YDR390C UBA2 E1-like (ubiquitin-activating) enzyme YDR392W SPT3 general transcriptional adaptor or co-activator YDR394W RPT3 26S proteasome regulatory subunit YDR395W SXM1 putative beta-karyopherin YDR397C NCB2 functional homolog of human NC2beta/Dr1 YDR404C RPB7 DNA-directed RNA polymerase II, 19 KD subunit YDR423C CAD1 transcriptional activator YDR427W RPN9 subunit of the regulatory particle of the proteasome YDR432W NPL3 nucleolar protein YDR443C SSN2 DNA-directed RNA polymerase II holoenzyme and Srb10 CDK subcomplex subunit YDR448W ADA2 general transcriptional adaptor or co-activator YDR463W STP1 pre-tRNA splicing protein, transcription factor YDR473C PRP3 essential splicing factor YDR480W DIG2 MAP kinase-associated protein, down-regulator of invasive growth and mating YEL009C GCN4 transcriptional activator of amino acid biosynthetic genes YEL032W MCM3 replication initiation protein YEL037C RAD23 nucleotide excision repair protein (ubiquitin-like protein) YEL061C CIN8 kinesin-related protein YER009W NTF2 nuclear transport factor YER012W PRE1 20S proteasome subunit C11(beta4) YER013W PRP22 pre-mRNA splicing factor YER021W RPN3 26S proteasome regulatory subunit YER022W SRB4 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YER029C SMB1 associated with U1 snRNP as part of the Sm-core that is common to all spliceosomal snRNPs YER040W GLN3 transcription factor for positive nitrogen regulation YER047C SAP1 member of the AAA-protein family YER068W MOT2 transcriptional repressor YER088C DOT6 involved in derepression of telomeric silencing YER094C PUP3 20S proteasome subunit (beta3) YER095W RAD51 DNA repair protein YER100W UBC6 E2 ubiquitin-conjugating enzyme YER105C NUP157 nuclear pore protein YER107C GLE2 required for nuclear pore complex structure and function YER109C FLO8 required for diploid filamentous growth YER110C KAP123 RAN-binding protein YER111C SWI4 transcription factor YER112W LSM4 Sm-like (Lsm) protein YER122C GLO3 zinc finger protein YER123W YCK3 casein kinase, isoform 3 YER142C MAG1 3-methyladenine DNA glycosylase YER146W LSM5 Sm-like (Lsm) protein YER148W SPT15 the TATA-binding protein TBP YER159C BUR6 functional homolog of human NC2alpha YER161C SPT2 multifunctional HMG-like chromatin protein YER162C RAD4 excision repair protein YER165W PAB1 mRNA polyadenylate-binding protein YER168C CCA1 tRNA nucleotidyltransferase YER171W RAD3 DNA helicase/ATPase YER172C BRR2 RNA helicase-related protein YER176W ECM32 DNA dependent ATPase/DNA helicase B YER179W DMC1 meiosis-specific protein YER184C YER184C similarity to multidrug resistance proteins PDR3P and PDR1P YFL001W DEG1 pseudouridine synthase YFL002C SPB4 ATP-dependent RNA helicase of DEAH box family YFL003C MSH4 meiosis-specific protein YFL008W SMC1 chromosome segregation protein YFL017W-A SMX2 snRNP G protein (the homologue of the human Sm-G) YFL021W GAT1 transcription factor for nitrogen regulation YFL031W HAC1 transcription factor YFR002W NIC96 nuclear pore protein YFR004W RPN11 26S proteasome regulatory subunit YFR023W PES4 DNA-directed DNA polymerase epsilon suppressor YFR031C SMC2 chromosome segregation protein YFR034C PHO4 transcription factor YFR036W CDC26 subunit of anaphase-promoting complex (cyclosome) YFR037C RSC8 subunit of the RSC complex YFR050C PRE4 20S proteasome subunit(beta7) YFR052W RPN12 26S proteasome regulatory subunit YGL011C SCL1 20S proteasome subunit YC7ALPHA/Y8 (alpha1) YGL013C PDR1 transcription factor YGL016W KAP122 Member of the karyopherin-beta family, nuclear import YGL019W CKB1 casein kinase II, beta subunit YGL025C PGD1 mediator complex subunit YGL033W HOP2 required for pairing of homologous chromosomes YGL035C MIG1 transcriptional repressor YGL043W DST1 TFIIS (transcription elongation factor) YGL044C RNA15 component of pre-mRNA 3'-end processing factor CF I YGL048C RPT6 26S proteasome regulatory subunit YGL058W RAD6 E2 ubiquitin-conjugating enzyme YGL070C RPB9 DNA-directed RNA polymerase II, 14.2 KD subunit YGL071W RCS1 iron-regulated transcriptional repressor YGL073W HSF1 heat shock transcription factor YGL078C DBP3 putative RNA helicase required for pre-rRNA processing YGL086W MAD1 spindle assembly checkpoint protein YGL090W LIF1 DNA ligase IV interacting factor YGL091C NBP35 nucleotide-binding protein YGL092W NUP145 nuclear pore protein YGL097W SRM1 GDP/GTP exchange factor for GSP1P/GSP2P YGL100W SEH1 nuclear pore protein YGL112C TAF60 TFIID and SAGA subunit YGL115W SNF4 nuclear regulatory protein YGL116W CDC20 cell division control protein YGL120C PRP43 involved in spliceosome disassembly YGL122C NAB2 nuclear poly(A)-binding protein YGL130W CEG1 mRNA guanylyltransferase (mRNA capping enzyme, alpha subunit) YGL133W ITC1 subunit of ISW2 chromatin remodelling complex YGL151W NUT1 negative transcription regulator from artifical reporters YGL163C RAD54 DNA-dependent ATPase of the SNF2P family YGL166W CUP2 copper-dependent transcription factor YGL172W NUP49 nuclear pore protein YGL181W GTS1 transcription factor of the GCS1P/GLO3P/SPS18P family YGL192W IME4 positive transcription factor for IME2 YGL201C MCM6 involved in replication YGL207W SPT16 general chromatin factor YGL208W SIP2 dominant suppressor of some ts mutations in RPO21 and PRP4 YGL216W KIP3 kinesin-related protein required for nuclear migration YGL237C HAP2 CCAAT-binding factor subunit YGL238W CSE1 importin-beta-like protein YGL241W KAP114 Member of the karyopherin-beta family, nuclear import YGL244W RTF1 regulates DNA binding properties of TBP YGL251C HFM1 DNA/RNA helicase YGL253W HXK2 hexokinase II YGL254W FZF1 sulfite resistance protein YGR005C TFG2 TFIIF subunit (transcription initiation factor), 54 kD YGR006W PRP18 U5 snRNA-associated protein YGR013W SNU71 associated with U1 snRNP, no counterpart in mammalian U1 snRNP YGR030C POP6 required for processing of tRNAs and rRNAs YGR040W KSS1 ser/thr protein kinase of the MAP kinase family YGR044C RME1 zinc-finger transcription factor YGR047C TFC4 TFIIIC (transcription initiation factor) subunit, 131 kD YGR056W RSC1 member of RSC complex, which remodels the structure of chromatin YGR063C SPT4 transcription elongation protein YGR072W UPF3 nonsense-mediated mRNA decay protein YGR074W SMD1 snRNA-associated protein YGR075C PRP38 pre-mRNA splicing factor YGR091W PRP31 pre-mRNA splicing protein YGR098C ESP1 required for sister chromatid separation YGR099W TEL2 involved in controlling telomere length and position effect YGR104C SRB5 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YGR116W SPT6 transcription elongation protein YGR119C NUP57 nuclear pore protein YGR135W PRE9 20S proteasome subunit Y13 (alpha3) YGR136W LSB1 weak similarity to chicken growth factor receptor-binding protein GRB2 homolog YGR140W CBF2 kinetochore protein complex CBF3, 110 KD subunit YGR158C MTR3 involved in mRNA transport YGR159C NSR1 nuclear localization sequence binding protein YGR178C PBP1 PAB1P interacting protein YGR180C RNR4 ribonucleotide reductase small subunit YGR186W TFG1 TFIIF subunit (transcription initiation factor), 105 kD YGR188C BUB1 ser/thr protein kinase YGR218W CRM1 nuclear export factor, exportin YGR229C SMI1 beta-1,3-glucan synthesis protein YGR232W NAS6 possible homolog of human 26S proteasome regulatory subunit p28 YGR246C BRF1 TFIIIB subunit, 70 kD YGR252W GCN5 histone acetyltransferase YGR253C PUP2 20S proteasome subunit(alpha5) YGR258C RAD2 structure-specific nuclease of the nucleotide excision repairosome YGR270W YTA7 26S proteasome subunit YGR274C TAF145 TFIID subunit (TBP-associated factor), 145 kD YGR285C ZUO1 zuotin, a putative Z-DNA binding protein YGR288W MAL13 maltose pathway regulatory protein YHL009C YAP3 transcription factor, of a fungal-specific family of bzip proteins YHL020C OPI1 negative regulator of phospholipid biosynthesis pathway YHL022C SPO11 catalytic subunit of the meiotic double strand break transesterase YHL025W SNF6 global transcription activator YHL027W RIM101 meiotic regulatory protein YHL034C SBP1 single-strand nucleic acid binding protein YHR004C NEM1 required for nuclear morphology YHR027C RPN1 26S proteasome regulatory subunit YHR041C SRB2 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YHR058C MED6 RNA polymerase II transcriptional regulation mediator YHR062C RPP1 required for processing of tRNA and 35S rRNA YHR065C RRP3 required for maturation of the 35S primary transcript YHR066W SSF1 mating protein YHR069C RRP4 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YHR072W-A NOP10 nucleolar rRNA processing protein YHR082C KSP1 ser/thr protein kinase YHR084W STE12 transcriptional activator YHR089C GAR1 nucleolar rRNA processing protein YHR090C YNG2 component of NuA4 histone acetyltransferase complex YHR118C ORC6 origin recognition complex, 50 KD subunit YHR119W SET1 involved in chromatin-mediated gene regulation YHR143W-A RPC10 DNA-directed RNA polymerases I, II, III 7.7 KD subunit YHR157W REC104 meiosis-specific protein YHR164C DNA2 DNA helicase YHR165C PRP8 U5 snRNP protein, pre-mRNA splicing factor YHR166C CDC23 subunit of anaphase-promoting complex (cyclosome) YHR184W SSP1 essential for meiosis and spore formation YHR195W NVJ1 part of nucleus-vacuole junctions YHR200W RPN10 26S proteasome regulatory subunit YHR206W SKN7 transcription factor with similarity to HSF1P YIL021W RPB3 DNA-directed RNA-polymerase II, 45 kDa YIL035C CKA1 casein kinase II, catalytic alpha chain YIL038C NOT3 general negative regulator of transcription, subunit 3 YIL046W MET30 involved in regulation of sulfur assimilation genes and cell cycle progression YIL061C SNP1 U1 small nuclear ribonucleoprotein YIL063C YRB2 involved in nuclear protein export YIL072W HOP1 meiosis-specific protein YIL075C RPN2 26S proteasome regulatory subunit YIL084C SDS3 transcriptional regulator YIL115C NUP159 nuclear pore protein YIL126W STH1 subunit of the RSC complex YIL128W MET18 involved in NER repair and RNA polymerase II transcription YIL129C TAO3 Transcriptional Activator of OCH1 YIL131C FKH1 forkhead protein, involved in transcriptional silencing, cell morphology and cell cycle YIL143C SSL2 DNA helicase YIL150C DNA43 required for S-phase initiation or completion YIR008C PRI1 DNA-directed DNA polymerase alpha 48kDa subunit (DNA primase) YIR015W RPR2 RNase P subunit YIR017C MET28 transcriptional activator of sulfur amino acid metabolism YIR018W YAP5 involved in transcription activation YIR023W DAL81 transcriptional activator for allantoin and GABA catabolic genes YIR033W MGA2 may be involved in the remodeling chromatin structure YJL001W PRE3 20S proteasome subunit (beta1) YJL006C CTK2 carboxy-terminal domain (CTD) kinase, beta subunit YJL013C MAD3 spindle-assembly checkpoint protein YJL025W RRN7 polymerase I specific transcription initiation factor YJL039C NUP192 nucleoporin localize at the inner site of the nuclear membrane YJL041W NSP1 nuclear pore protein YJL050W MTR4 involved in nucleocytoplasmic transport of mRNA YJL056C ZAP1 metalloregulatory protein involved in zinc-responsive transcriptional regulation YJL061W NUP82 nuclear pore protein YJL080C SCP160 required for maintenance of exact ploidy YJL081C ARP4 actin-related protein YJL087C TRL1 tRNA ligase YJL089W SIP4 interacts with SNF1 protein kinase YJL090C DPB11 involved in DNA replication and S-phase checkpoint YJL092W HPR5 ATP-dependent DNA helicase YJL103C YJL103C similarity to YBR239c YJL110C GZF3 transcriptional repressor YJL127C SPT10 transcription regulatory protein YJL130C URA2 multifunctional pyrimidine biosynthesis protein YJL140W RPB4 DNA-directed RNA polymerase II, 32 kDa subunit YJL148W RPA34 nonessential component of RNA-polI YJL157C FAR1 cyclin-dependent kinase inhibitor (CKI) YJL173C RFA3 DNA replication factor A, 13 KD subunit YJL176C SWI3 transcription regulatory protein YJL194W CDC6 cell division control protein YJL203W PRP21 pre-mRNA splicing factor YJR002W MPP10 component of the U3 small nucleolar ribonucleoprotein YJR006W HYS2 DNA-directed DNA polymerase delta, 55 KD subunit YJR021C REC107 meiotic recombination protein YJR022W LSM8 splicing factor YJR035W RAD26 DNA repair and recombination protein YJR042W NUP85 nuclear pore protein YJR043C POL32 polymerase-associated gene, third (55 kDa) subunit of DNA polymerase delta YJR052W RAD7 nucleotide excision repair protein YJR060W CBF1 kinetochore protein YJR063W RPA12 DNA-directed RNA polymerase I, 13.7 KD subunit YJR068W RFC2 DNA replication factor C, 41 KD subunit YJR093C FIP1 component of pre-mRNA polyadenylation factor PF I YJR094C IME1 transcription factor required for sporulation YJR112W NNF1 nuclear envelope protein YJR122W CAF17 CCR4 associated factor YKL005C YKL005C weak similarity to YKR029c and D.melanogaster transcription elongation factor DmS-II YKL012W PRP40 splicing factor YKL015W PUT3 positive activator of the proline utilisation pathway YKL020C SPT23 dosage-dependent suppressor of Ty-induced promotor mutations YKL022C CDC16 subunit of anaphase-promoting complex (cyclosome) YKL024C URA6 uridine-monophosphate kinase YKL028W TFA1 TFIIE subunit (transcription initiation factor), 66 kD YKL032C IXR1 intrastrand crosslink recognition protein and transcription factor YKL038W RGT1 regulator of glucose-induced genes YKL043W PHD1 transcription factor YKL045W PRI2 DNA-directed DNA polymerase alpha , 58 KD subunit (DNA primase) YKL049C CSE4 component of the core centromere YKL057C NUP120 nuclear pore protein YKL058W TOA2 TFIIA subunit (transcription initiation factor), 13.5 kD YKL062W MSN4 transcriptional activator YKL068W NUP100 nuclear pore protein YKL074C MUD2 pre-mRNA splicing factor YKL089W MIF2 required for normal chromosome segregation and spindle integrity YKL095W YJU2 similarity to C.elegans hypothetical proteins YKL101W HSL1 ser/thr protein kinase, coupling septin ring assembly to cell cycle progression YKL108W SLD2 chromosomal DNA replication protein YKL109W HAP4 CCAAT-binding factor subunit YKL112W ABF1 ARS-binding factor YKL113C RAD27 ssDNA endonuclease and 5'-3'exonuclease YKL114C APN1 AP endonuclease YKL125W RRN3 RNA polymerase I specific transcription factor YKL139W CTK1 carboxy-terminal domain (CTD) kinase, alpha subunit YKL144C RPC25 DNA-direcred RNA polymerase III, 25 KD subunit YKL145W RPT1 26S proteasome regulatory subunit YKL149C DBR1 lariat-debranching enzyme YKL185W ASH1 negative regulator of HO transcription YKL186C MTR2 mRNA transport protein YKL193C SDS22 regulatory subunit for the mitotic function of type I protein phosphatase YKL205W LOS1 pre-tRNA splicing protein YKL210W UBA1 E1-like (ubiquitin-activating) enzyme YKL222C YKL222C weak similarity to transcription factors, similarity to finger proteins YOR162c, YOR172w and YLR266c YKR002W PAP1 poly(A) polymerase YKR008W RSC4 member of RSC complex, which remodels the structure of chromatin YKR034W DAL80 transcriptional repressor for allantoin and GABA catabolic genes YKR048C NAP1 nucleosome assembly protein I YKR054C DYN1 dynein heavy chain, cytosolic YKR056W RNC1 tRNA(m5U54)methyltransferase YKR062W TFA2 TFIIE subunit (transcription initiation factor), 43 KD YKR063C LAS1 involved in cell morphogenesis, cytoskeletal regulation and bud formation YKR064W YKR064W weak similarity to transcription factors YKR072C SIS2 involved in cell cycle-specific gene expression YKR082W NUP133 nuclear pore protein YKR086W PRP16 RNA-dependent ATPase YKR092C SRP40 suppressor of mutant AC40 of RNA polymerase I and III YKR095W MLP1 myosin-like protein related to USO1P YKR099W BAS1 transcription factor YKR101W SIR1 silencing regulatory protein YLL004W ORC3 origin recognition complex, 62 kDa subunit YLL008W DRS1 RNA helicase of the DEAD box family YLL011W SOF1 involved in 18S pre-rRNA production YLL036C PRP19 non-snRNP sliceosome component required for DNA repair YLL039C UBI4 ubiquitin YLR014C PPR1 transcription factor regulating pyrimidine pathway YLR032W RAD5 DNA helicase YLR055C SPT8 transcriptional adaptor or co-activator YLR071C RGR1 DNA-directed RNA polymerase II holoenzyme subunit YLR098C CHA4 transcription factor YLR103C CDC45 required for minichromosome maintenance and initiation of chromosomal DNA replication YLR105C SEN2 tRNA splicing endonuclease beta subunit YLR115W CFT2 cleavage and polyadenylation specificity factor, part of CF II YLR116W MSL5 branch point bridging protein YLR131C ACE2 metallothionein expression activator YLR141W RRN5 RNA polymerase I specific transcription initiation factor YLR147C SMD3 spliceosomal snRNA-associated Sm core protein required for pre-mRNA splicing YLR175W CBF5 putative rRNA pseuduridine synthase YLR176C RFX1 repressor of DNA damage-inducible genes YLR182W SWI6 transcription factor YLR197W SIK1 involved in pre-rRNA processing YLR223C IFH1 pre-rRNA processing machinery control protein YLR233C EST1 telomere elongation protein YLR234W TOP3 DNA topoisomerase III YLR256W HAP1 transcription factor YLR263W RED1 meiosis-specific protein YLR266C YLR266C weak similarity to transcription factors YLR272C YCS4 subunit of condensin protein complex YLR274W CDC46 cell division control protein YLR275W SMD2 U1 snRNP protein of the Sm class YLR277C YSH1 component of pre-mRNA polyadenylation factor PF I YLR293C GSP1 GTP-binding protein of the ras superfamily YLR298C YHC1 associated with the U1 snRNP complex YLR318W EST2 catalytic subunit of the telomerase YLR321C SFH1 subunit of the RSC complex YLR329W REC102 meiotic recombination protein YLR335W NUP2 nuclear pore protein YLR398C SKI2 antiviral protein and putative helicase YLR399C BDF1 sporulation protein YLR403W SFP1 zinc finger protein YLR418C CDC73 DNA-directed RNA polymerase II accessory protein YLR430W SEN1 positive effector of tRNA-splicing endonuclease YLR438C-A LSM3 Sm-like (Lsm) protein YLR442C SIR3 silencing regulatory and DNA-repair protein YLR451W LEU3 transcription factor YLR453C RIF2 RAP1P interacting factor 2 YML007W YAP1 transcriptional activator involved in oxidative stress response YML010W SPT5 transcription elongation protein YML015C TAF40 TFIID subunit (TBP-associated factor), 40KD YML021C UNG1 uracil-DNA glycosylase YML027W YOX1 homoeodomain protein YML031W NDC1 nuclear envelope protein YML032C RAD52 recombination and DNA repair protein YML043C RRN11 RNA polymerase I specific transcription initiation factor YML046W PRP39 pre-mRNA splicing factor YML051W GAL80 negative regulator for expression of galactose-induced genes YML060W OGG1 8-oxoguanine DNA glycosylase YML061C PIF1 DNA helicase involved in mitochondrial DNA repair and telomere length YML065W ORC1 origin recognition complex, 104 KD subunit YML069W POB3 protein that binds to DNA polymerase I (PolI) YML074C NPI46 proline cis-trans isomerase YML076C YML076C weak similarity to transcription factor YML092C PRE8 20S proteasome subunit Y7 (alpha2) YML095C RAD10 DNA repair protein YML098W TAF19 TFIID subunit (TBP-associated factor), 19 kD YML099C ARG81 transcription factor involved in arginine metabolism YML102W CAC2 chromatin assembly complex, subunit p60 YML103C NUP188 nuclear pore protein YML112W CTK3 carboxy-terminal domain (CTD) kinase, gamma subunit YML113W DAT1 datin, oligo(dA)/oligo(dT)-binding protein YMR001C CDC5 involved in regulation of DNA replication YMR016C SOK2 regulatory protein in the PKA signal transduction pathway YMR019W STB4 weak similarity to YIL130w, PUT3P and other transcription factors YMR021C MAC1 metal binding activator YMR037C MSN2 stress responsive regulatory protein YMR039C SUB1 transcriptional coactivator YMR042W ARG80 transcription factor involved in arginine metabolism YMR043W MCM1 transcription factor of the MADS box family YMR047C NUP116 nuclear pore protein YMR059W SEN15 tRNA splicing endonuclease delta subunit YMR061W RNA14 component of pre-mRNA 3'-end processing factor CF I YMR072W ABF2 high mobility group protein YMR078C CTF18 required for accurate chromosome transmission in mitosis and maintenance of normal telomere length YMR094W CTF13 kinetochore protein complex, CBF3, 58 KD subunit YMR106C YKU80 component of DNA end-joining repair pathway YMR112C MED11 mediator complex subunit YMR125W STO1 large subunit of the nuclear cap-binding protein complex CBC YMR128W ECM16 putative DEAH-box RNA helicase YMR129W POM152 nuclear pore membrane glycoprotein YMR133W REC114 meiotic recombination protein YMR137C PSO2 DNA repair protein YMR139W RIM11 ser/thr protein kinase YMR167W MLH1 DNA mismatch repair protein YMR168C CEP3 kinetochore protein complex, 71 KD subunit YMR179W SPT21 required for normal transcription at a number of loci YMR182C RGM1 transcriptional repressor protein YMR201C RAD14 nucleotide excision repair protein YMR224C MRE11 DNA repair and meiotic recombination protein YMR227C TAF67 TFIID subunit (TBP-associated factor), 67 kD YMR229C RRP5 processing of pre-ribosomal RNA YMR236W TAF17 TFIID and SAGA subunit YMR239C RNT1 double-stranded ribonuclease YMR240C CUS1 U2 snRNP protein YMR241W YHM2 yeast suppressor gene of HM (mitochondrial histone) mutant (ABF2) YMR268C PRP24 pre-mRNA splicing factor YMR270C RRN9 RNA polymerase I specific transcription initiation factor YMR276W DSK2 ubiquitin-like protein YMR277W FCP1 TFIIF interacting component of CTD phosphatase YMR280C CAT8 transcription factor involved in gluconeogenesis YMR284W YKU70 high-affinity DNA-binding protein YMR308C PSE1 beta karyopherin YMR314W PRE5 20S proteasome subunit(alpha6) YNL007C SIS1 heat shock protein YNL012W SPO1 transcriptional regulator involved in sporulation YNL016W PUB1 major polyadenylated RNA-binding protein of nucleus and cytoplasm YNL021W HDA1 histone deacetylase A YNL025C SSN8 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit, cyclin C homolog YNL030W HHF2 histone H4 YNL031C HHT2 histone H3 YNL039W BDP1 TFIIIB subunit, 90 kD YNL059C ARP5 Actin-related protein YNL061W NOP2 nucleolar protein YNL068C FKH2 homology to D.melanogaster forkhead protein YNL082W PMS1 DNA mismatch repair protein YNL088W TOP2 DNA topoisomerase II (ATP-hydrolysing) YNL102W POL1 DNA-directed DNA polymerase alpha, 180 KD subunit YNL103W MET4 transcriptional activator of sulfur metabolism YNL112W DBP2 ATP-dependent RNA helicase of DEAD box family YNL113W RPC19 DNA-directed RNA polymerase I,III 16 KD subunit YNL126W SPC98 spindle pole body component YNL147W LSM7 Sm-like (Lsm) protein YNL151C RPC31 DNA-directed RNA polymerase III, 31 KD subunit YNL167C SKO1 cre-binding bzip protein YNL172W APC1 subunit of anaphase-promoting complex (cyclosome) YNL189W SRP1 karyopherin-alpha or importin YNL199C GCR2 glycolytic genes transcriptional activator YNL204C SPS18 sporulation-specific zinc-finger protein YNL206C RTT106 similarity to structure-specific recognition proteins YNL210W MER1 meiotic recombination protein YNL216W RAP1 DNA-binding protein with repressor and activator activity YNL220W ADE12 adenylosuccinate synthetase YNL221C POP1 protein component of ribonuclease P and ribonuclease MRP YNL222W SSU72 suppressor of cs mutant of SUA7 YNL236W SIN4 global regulator protein YNL248C RPA49 DNA-directed RNA polymerase A (I) chain, 46 kDa YNL250W RAD50 DNA repair protein YNL251C NRD1 involved in regulation of nuclear pre-mRNA abundance YNL261W ORC5 origin recognition complex, 50 kDa subunit YNL262W POL2 DNA-directed DNA polymerase epsilon, catalytic subunit A YNL267W PIK1 phosphatidylinositol 4-kinase YNL282W POP3 involved in processsing of tRNAs and rRNAs YNL290W RFC3 DNA replication factor C, 40 kDa subunit YNL292W PUS4 pseudouridine synthase YNL312W RFA2 DNA replication factor A, 36 kDa subunit YNL314W DAL82 transcriptional activator for allantoin catabolic genes YNL330C RPD3 histone deacetylase B YNR003C RPC34 DNA-directed RNA polymerase III, 34 KD subunit YNR010W CSE2 subunit of RNA polymerase II mediator complex YNR011C PRP2 RNA-dependent ATPase of DEAH box family YNR023W SNF12 component of SWI/SNF global transcription activator complex YNR038W DBP6 RNA helicase required for 60S ribosomal subunit assembly YNR052C POP2 required for glucose derepression YOL001W PHO80 cyclin YOL004W SIN3 transcription regulatory protein YOL005C RPB11 DNA-directed RNA polymerase II subunit, 13.6 kD YOL006C TOP1 DNA topoisomerase I YOL012C HTZ1 evolutionarily conserved member of the histone H2A F/Z family of histone variants YOL021C DIS3 3'->5' exoribonuclease required for 3' end formation of 5.8S rRNA YOL028C YAP7 involved in transcription activation YOL038W PRE6 20S proteasome subunit (alpha4) YOL051W GAL11 DNA-directed RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex subunit YOL067C RTG1 basic helix-loop-helix transcription factor that regulates CIT2 gene expression YOL089C HAL9 transcriptional activator of ENA1 YOL090W MSH2 DNA mismatch repair protein YOL094C RFC4 DNA replication factor C, 37 kDa subunit YOL104C NDJ1 meiotic telomere protein YOL108C INO4 basic helix-loop-helix transcription factor YOL115W TRF4 topoisomerase I-related protein YOL116W MSN1 transcriptional activator YOL123W HRP1 CF Ib (RNA3' Cleavage factor Ib) YOL133W HRT1 similarity to Lotus RING-finger protein YOL135C MED7 member of RNA Polymerase II transcriptional regulation mediator complex YOL148C SPT20 member of the TBP class of SPT proteins that alter transcription site selection YOR005C DNL4 DNA ligase IV YOR028C CIN5 transcriptional activator YOR038C HIR2 histone transcription regulator YOR039W CKB2 casein kinase II beta' chain YOR048C RAT1 5'-3' exoribonuclease YOR058C ASE1 microtubule-associated protein (nonmotor) YOR061W CKA2 casein kinase II alpha' chain YOR074C CDC21 thymidylate synthase YOR098C NUP1 nuclear pore protein YOR110W TFC7 TFIIIC (transcription initiation factor) subunit, 55 kDa YOR113W AZF1 asparagine-rich zinc finger protein YOR116C RPO31 DNA-directed RNA polymerase III, 160 KD subunit YOR117W RPT5 26S proteasome regulatory subunit YOR140W SFL1 transcription factor YOR151C RPB2 DNA-directed RNA polymerase II, 140 kDa chain YOR157C PUP1 20S proteasome subunit (beta2) YOR159C SME1 spliceosomal snRNA-associated Sm core protein required for mRNA splicing, also likely associated with telomerase TLC1 RNA YOR160W MTR10 involved in nuclear protein import YOR162C YRR1 transcription factor YOR174W MED4 transcription regulation mediator YOR185C GSP2 GTP-binding protein of the RAS superfamily YOR194C TOA1 TFIIA subunit (transcription initiation factor), 32 kD YOR204W DED1 ATP-dependent RNA helicase YOR207C RET1 DNA-directed RNA polymerase III, 130 KD subunit YOR210W RPB10 DNA-directed polymerase I, II, III 8.3 subunit YOR213C SAS5 subunit of the RSC complex YOR217W RFC1 DNA replication factor C, 95 KD subunit YOR224C RPB8 DNA-directed RNA polymerase I, II, III 16 KD subunit YOR229W WTM2 transcriptional modulator YOR230W WTM1 transcriptional modulator YOR250C CLP1 cleavage/polyadenylation factor IA subunit YOR259C RPT4 26S proteasome regulatory subunit YOR261C RPN8 26S proteasome regulatory subunit YOR274W MOD5 tRNA isopentenyltransferase YOR290C SNF2 component of SWI/SNF global transcription activator complex YOR310C NOP58 required for pre-18S rRNA processing YOR319W HSH49 essential yeast splicing factor YOR337W TEA1 TY1 enhancer activator YOR340C RPA43 DNA-directed RNA polymerase I, 36 KD subunit YOR341W RPA190 DNA-directed RNA polymerase I, 190 KD alpha subunit YOR344C TYE7 basic helix-loop-helix transcription factor YOR351C MEK1 ser/thr protein kinase YOR358W HAP5 CCAAT-binding factor subunit YOR362C PRE10 20S proteasome subunit C1 (alpha7) YOR363C PIP2 peroxisome proliferating transcription factor YOR386W PHR1 deoxyribodipyrimidine photo-lyase YPL001W HAT1 histone acetyltransferase subunit YPL008W CHL1 protein of the DEAH box family YPL016W SWI1 component of SWI/SNF global transcription activator complex YPL022W RAD1 component of the nucleotide excision repairosome YPL031C PHO85 cyclin-dependent protein kinase YPL037C EGD1 GAL4 DNA-binding enhancer protein YPL042C SSN3 cyclin-dependent CTD kinase YPL043W NOP4 nucleolar protein YPL046C ELC1 Elongin C transcription elongation factor YPL049C DIG1 MAP kinase-associated protein, down-regulator of invasive growth and mating YPL075W GCR1 transcriptional activator YPL082C MOT1 transcriptional accessory protein YPL083C SEN54 tRNA splicing endonuclease alpha subunit YPL089C RLM1 transcription factor of the MADS box family YPL119C DBP1 ATP-dependent RNA helicase YPL122C TFB2 TFIIH subunit (transcription/repair factor) YPL126W NAN1 weak similarity to fruit fly TFIID subunit p85 YPL127C HHO1 histone H1 protein YPL128C TBF1 telomere TTAGGG repeat-binding factor 1 YPL129W ANC1 TFIIF subunit (transcription initiation factor), 30 kD YPL133C YPL133C weak similarity to transcription factors YPL139C UME1 negative regulator of meiosis YPL153C RAD53 ser/thr/tyr protein kinase YPL167C REV3 DNA-directed DNA polymerase zeta subunit YPL169C MEX67 factor for nuclear mRNA export YPL177C CUP9 involved in copper homeostasis repression of protein import YPL178W CBC2 small subunit of the nuclear cap-binding protein complex CBC YPL190C NAB3 polyadenylated RNA-binding protein YPL204W HRR25 casein kinase I, ser/thr/tyr protein kinase YPL211W NIP7 required for efficient 60S ribosome subunit biogenesis YPL212C PUS1 pseudouridine synthase 1 YPL248C GAL4 transcription factor YPL254W HFI1 transcriptional coactivator YPL266W DIM1 rRNA (adenine-N6,N6-)-dimethyltransferase YPR010C RPA135 DNA-directed RNA polymerase I, 135 KD subunit YPR018W RLF2 chromatin assembly complex, subunit p90 YPR019W CDC54 member of the CDC46P/MCM2P/MCM3P family YPR025C CCL1 TFIIH subunit (transcription initiation factor), cyclin C component YPR033C HTS1 histidine--tRNA ligase, mitochondrial YPR045C YPR045C similarity to C.elegans hypothetical protein YPR052C NHP6A nonhistone chromosomal protein related to mammalian HMG1 YPR056W TFB4 component of RNA polymerase transcription initiation TFIIH factor YPR057W BRR1 involved in snRNP biogenesis YPR065W ROX1 heme-dependent transcriptional repressor of hypoxic genes YPR086W SUA7 TFIIB subunit (transcription initiation factor), factor E YPR101W SNT309 splicing factor YPR103W PRE2 20S proteasome subunit (beta5) YPR104C FHL1 transcriptional activator of the forkhead/hnf3 family YPR108W RPN7 subunit of the regulatory particle of the proteasome YPR110C RPC40 DNA-directed RNA polymerase I, III 40 KD subunit YPR133C IWS1 similarity to C.elegans hypothetical protein YPR135W CTF4 DNA-directed DNA polymerase alpha-binding protein YPR162C ORC4 origin recognition complex, 56 KD subunit YPR168W NUT2 negative transcription regulator from artifical reporters YPR175W DPB2 DNA-directed DNA polymerase epsilon, subunit B YPR178W PRP4 U4/U6 snRNP 52 KD protein YPR182W SMX3 snRNA-associated protein of the SM family YPR186C PZF1 TFIIIA (transcription initiation factor) YPR187W RPO26 DNA-directed RNA polymerase I, II, III 18 KD subunit YPR189W SKI3 antiviral protein YPR190C RPC82 DNA-directed RNA polymerase III, 82 KD subunit YPR196W YPR196W strong similarity to regulatory protein Mal63p chromosome (44 ORFs) 40.10.03 44 YBL002W HTB2 histone H2B.2 YBL003C HTA2 histone H2A.2 YBR009C HHF1 histone H4 YBR010W HHT1 histone H3 YBR089C-A NHP6B nonhistone chromosomal protein YBR158W CST13 weak similarity to TRCDSEMBL:AF176518_1 F-box protein FBL2; human YBR275C RIF1 RAP1-interacting factor 1 YCL011C GBP2 potential telomere-associated protein YCR052W RSC6 subunit of the RSC complex YDL220C CDC13 cell division control protein YDR082W STN1 involved in telomere length regulation YDR174W HMO1 Non-histone protein YDR224C HTB1 histone H2B YDR225W HTA1 histone H2A YDR285W ZIP1 synaptonemal complex protein YDR318W MCM21 involved in minichromosome maintenance YER161C SPT2 multifunctional HMG-like chromatin protein YFR037C RSC8 subunit of the RSC complex YGL033W HOP2 required for pairing of homologous chromosomes YGL133W ITC1 subunit of ISW2 chromatin remodelling complex YGR056W RSC1 member of RSC complex, which remodels the structure of chromatin YGR099W TEL2 involved in controlling telomere length and position effect YGR285C ZUO1 zuotin, a putative Z-DNA binding protein YHR090C YNG2 component of NuA4 histone acetyltransferase complex YIL126W STH1 subunit of the RSC complex YJR060W CBF1 kinetochore protein YKL049C CSE4 component of the core centromere YKL089W MIF2 required for normal chromosome segregation and spindle integrity YLR272C YCS4 subunit of condensin protein complex YML102W CAC2 chromatin assembly complex, subunit p60 YMR072W ABF2 high mobility group protein YMR094W CTF13 kinetochore protein complex, CBF3, 58 KD subunit YMR168C CEP3 kinetochore protein complex, 71 KD subunit YMR241W YHM2 yeast suppressor gene of HM (mitochondrial histone) mutant (ABF2) YNL030W HHF2 histone H4 YNL031C HHT2 histone H3 YOL012C HTZ1 evolutionarily conserved member of the histone H2A F/Z family of histone variants YOL104C NDJ1 meiotic telomere protein YOR213C SAS5 subunit of the RSC complex YPL126W NAN1 weak similarity to fruit fly TFIID subunit p85 YPL127C HHO1 histone H1 protein YPL128C TBF1 telomere TTAGGG repeat-binding factor 1 YPR018W RLF2 chromatin assembly complex, subunit p90 YPR052C NHP6A nonhistone chromosomal protein related to mammalian HMG1 mitochondrion (366 ORFs) 40.16 366 YAL010C MDM10 involved in mitochondrial morphology and inheritance YAL011W FUN36 weak similarity to Mus musculus p53-associated cellular protein YAL039C CYC3 holocytochrome-c synthase (cytochrome c heme lyase) YAL044C GCV3 glycine decarboxylase, subunit H YAL054C ACS1 acetyl-CoA synthetase YAR035W YAT1 carnitine acetyltransferase, mitochondrial YBL013W FMT1 Methionyl-tRNA Transformylase YBL022C PIM1 ATP-dependent protease, mitochondrial YBL030C PET9 ADP/ATP carrier protein (MCF) YBL038W MRPL16 ribosomal protein of the large subunit, mitochondrial YBL045C COR1 ubiquinol--cytochrome-c reductase 44K core protein YBL080C PET112 required to maintain rho+ mitochondrial DNA YBL090W MRP21 Mitochondrial ribosomal protein YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBR003W COQ1 hexaprenyl pyrophosphate synthetase precursor YBR024W SCO2 involved in stability of COX1P and COX2P YBR029C CDS1 CDP-diacylglycerol synthase YBR037C SCO1 involved in stabilization of COX1P and COX2P YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR044C TCM62 chaperone required for assembly of mitochondrial succinate dehydrogenase YBR084W MIS1 C1-tetrahydrofolate synthase precursor, mitochondrial YBR085W AAC3 ADP/ATP carrier protein (MCF) YBR091C MRS5 subunit of the TIM22-complex YBR104W YMC2 mitochondrial carrier protein (MCF) YBR120C CBP6 apo-cytochrome B pre-mRNA processing protein YBR122C MRPL36 ribosomal protein YmL36 precursor, mitochondrial YBR146W MRPS9 ribosomal protein S9 precursor, mitochondrial YBR179C FZO1 required for biogenesis of mitochondria YBR185C MBA1 respiratory chain assembly protein YBR192W RIM2 mitochondrial carrier protein (MCF) YBR221C PDB1 pyruvate dehydrogenase (lipoamide) beta chain precursor YBR227C MCX1 similarity to E.coli ATP-binding protein clpX YBR251W MRPS5 ribosomal protein S5, mitochondrial YBR263W SHM1 serine hydroxymethyltransferase precursor, mitochondrial YBR268W MRPL37 ribosomal protein YmL37, mitochondrial YBR282W MRPL27 ribosomal protein YmL27 precursor, mitochondrial YBR291C CTP1 citrate transport protein, mitochondrial (MCF) YCL004W PGS1 phosphatidylglycerophosphate synthase YCL009C ILV6 acetolactate synthase, regulatory subunit YCL017C NFS1 regulates Iron-Sulfur cluster proteins, cellular Iron uptake, andIron distribution YCL057W PRD1 proteinase yscD YCR003W MRPL32 ribosomal protein YmL32, mitochondrial YCR028C-A RIM1 ssDNA-binding protein, mitochondrial YCR046C IMG1 ribosomal protein, mitochondrial YCR083W TRX3 mitochondrial thioredoxin YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL044C MTF2 mitochondrial protein involved in mRNA splicing and protein synthesis YDL045W-A MRP10 mitochondrial ribosomal protein YDL066W IDP1 isocitrate dehydrogenase (NADP+), mitochondrial YDL067C COX9 cytochrome-c oxidase chain VIIA YDL069C CBS1 translational activator of COB mRNA YDL119C YDL119C similarity to bovine Graves disease carrier protein YDL120W YFH1 regulates mitochondrial iron accumulation YDL130W-A STF1 ATPase stabilizing factor, 10 kDa YDL174C DLD1 D-lactate ferricytochrome C oxidoreductase (D-LCR) YDL181W INH1 inhibitor of mitochondrial ATPase YDL198C YHM1 member of the mitochondrial carrier family (MCF) YDL202W MRPL11 ribosomal protein of the large subunit, mitochondrial YDL217C TIM22 subunit of the TIM22-complex YDR019C GCV1 glycine decarboxylase, subunit T YDR035W ARO3 2-dehydro-3-deoxyphosphoheptonate aldolase, phenylalanine-inhibited YDR074W TPS2 alpha,alpha-trehalose-phosphate synthase, 102 KD subunit YDR079W PET100 cytochrome-c oxidase assembly protein YDR120C TRM1 N2,N2-dimethylguanine tRNA methyltransferase YDR148C KGD2 2-oxoglutarate dehydrogenase complex E2 component YDR178W SDH4 succinate dehydrogenase membrane anchor subunit for SDH2P YDR194C MSS116 RNA helicase of the DEAD box family, mitochondrial YDR197W CBS2 cytochrome B translational activator protein YDR231C COX20 in the maturation and assembly of cytochrome oxidase involved protein YDR232W HEM1 5-aminolevulinate synthase YDR234W LYS4 homoaconitase YDR237W MRPL7 ribosomal protein of the large subunit, mitochondrial YDR258C HSP78 heat shock protein of clpb family of ATP-dependent proteases, mitochondrial YDR268W MSW1 tryptophanyl-tRNA synthetase, mitochondrial YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR322C-A TIM11 subunit E of the dimeric form of mitochondrial F1F0-ATPase YDR322W MRPL35 ribosomal protein YmL35 of the large subunit, mitochondrial YDR337W MRPS28 ribosomal protein of the small subunit, mitochondrial YDR347W MRP1 ribosomal protein of the small subunit, mitochondrial YDR375C BCS1 mitochondrial protein of the CDC48/PAS1/SEC18 (AAA) family of ATPases YDR376W ARH1 mitochondrial protein with similarity to human adrenodoxin reductase and ferredoxin-NADP+ reductase YDR377W ATP17 ATP synthase complex, subunit f YDR405W MRP20 ribosomal protein of the large subunit, mitochondrial YDR456W NHX1 NA+-H+ antiporter YDR462W MRPL28 ribosomal protein of the large subunit (YmL28), mitochondrial YDR529C QCR7 ubiquinol--cytochrome-c reductase subunit 7 YEL020W-A TIM9 essential subunit of the TIM22-complex for mitochondrial protein import YEL024W RIP1 ubiquinol--cytochrome-c reductase iron-sulfur protein precursor YEL039C CYC7 cytochrome-c isoform 2 YEL050C RML2 ribosomal L2 protein, mitochondrial YEL059C-A SOM1 required for mitochondrial IMP1 peptidase function YER014W HEM14 protoporphyrinogen oxidase, mitochondrial YER017C AFG3 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YER026C CHO1 CDP-diacylglycerol serine O-phosphatidyltransferase YER058W PET117 cytochrome c oxidase assembly factor YER061C CEM1 beta-keto-acyl-ACP synthase, mitochondrial YER069W ARG5,6 acetylglutamate kinase and acetylglutamyl-phosphate reductase YER073W ALD5 aldehyde dehydrogenase (NAD+), mitochondrial YER086W ILV1 anabolic serine and threonine dehydratase precursor YER141W COX15 cytochrome oxidase assembly factor YER153C PET122 translational activator of cytochrome c oxidase subunit III YER154W OXA1 cytochrome oxidase biogenesis protein YER168C CCA1 tRNA nucleotidyltransferase YER170W ADK2 adenylate kinase, mitochondrial YER178W PDA1 pyruvate dehydrogenase (lipoamide) alpha chain precursor YFL016C MDJ1 heat shock protein - chaperone YFL018C LPD1 dihydrolipoamide dehydrogenase precursor YFL036W RPO41 DNA-directed RNA polymerase, mitochondrial YFR033C QCR6 ubiquinol--cytochrome-c reductase 17K protein YFR049W YMR31 ribosomal protein, mitochondrial YGL018C JAC1 molecular chaperone YGL068W YGL068W strong similarity to Cricetus mitochrondial ribosomal L12 protein YGL119W ABC1 ubiquinol--cytochrome-c reductase complex assembly protein YGL125W MET13 putative methylene tetrahydrofolate reductase YGL143C MRF1 peptide chain release factor, mitochondrial YGL187C COX4 cytochrome-c oxidase chain IV YGL191W COX13 cytochrome-c oxidase chain VIa YGL236C MTO1 strong similarity to gidA E.coli protein YGR008C STF2 ATPase stabilizing factor YGR028W MSP1 intra-mitochondrial sorting protein YGR029W ERV1 mitochondrial biogenesis and regulation of cell cycle YGR062C COX18 required for activity of mitochondrial cytochrome oxidase YGR076C MRPL25 ribosomal protein YmL25, mitochondrial YGR082W TOM20 mitochondrial outer membrane import receptor subunit, 20 kD YGR084C MRP13 ribosomal protein of the small subunit, mitochondrial YGR094W VAS1 valyl-tRNA synthetase YGR112W SHY1 SURF homologue protein YGR171C MSM1 methionyl-tRNA synthetase YGR174C CBP4 ubiquinol--cytochrome-c reductase assembly factor YGR183C QCR9 ubiquinol--cytochrome-c reductase subunit 9 YGR193C PDX1 pyruvate dehydrogenase complex protein X YGR207C ETF-BETA electron-transferring flavoprotein, beta chain YGR220C MRPL9 ribosomal protein YmL9, mitochondrial YGR222W PET54 splicing protein and translational activator, mitochondrial YHL004W MRP4 ribosomal protein of the small subunit, mitochondrial YHL038C CBP2 apo-cytochrome b pre-mRNA processing protein 2 YHR001W-A QCR10 ubiquinol--cytochrome-c reductase 8.5 kDa subunit YHR005C-A MRS11 subunit of the TIM22-complex YHR008C SOD2 superoxide dismutase (Mn) precursor, mitochondrial YHR024C MAS2 processing peptidase, catalytic 53kDa (alpha) subunit, mitochondrial YHR037W PUT2 1-pyrroline-5-carboxylate dehydrogenase YHR038W FIL1 Killed in Mutagen, sensitive to Diepoxybutane and/or Mitomycin C YHR050W SMF2 probable manganese transporter YHR051W COX6 cytochrome-c oxidase subunit VI YHR075C PPE1 ribosomal protein of the small subunit, mitochondrial YHR076W YHR076W weak similarity to C.elegans hypothetical protein CEW09D10 YHR091C MSR1 arginyl-tRNA synthetase, mitochondrial YHR117W TOM71 protein with similarity to TOM70P/Mas70p YHR120W MSH1 DNA mismatch repair protein, mitochondrial YHR147C MRPL6 ribosomal protein of the large subunit, mitochondrial YHR208W BAT1 branched chain amino acid aminotransferase, mitochondrial YIL022W TIM44 mitochondrial inner membrane import receptor subunit YIL043C CBR1 cytochrome-b5 reductase YIL070C MAM33 mitochondrial acidic matrix protein YIL111W COX5B cytochrome-c oxidase chain Vb YIL114C POR2 voltage dependent anion channel (YVDAC2) YIL125W KGD1 2-oxoglutarate dehydrogenase complex E1 component YIL134W FLX1 FAD carrier protein (MCF), mitochondrial YIL136W OM45 protein of the outer mitochondrial membrane YIL155C GUT2 glycerol-3-phosphate dehydrogenase, mitochondrial YIR021W MRS1 involved in mitochondrial RNA splicing of COB mRNA YJL023C PET130 protein synthesis protein, mitochondrial YJL054W TIM54 translocase for the insertion of proteins into the mitochondrial inner membrane YJL063C MRPL8 ribosomal protein L17, mitochondrial YJL096W MRPL49 ribosomal protein YmL49, mitochondrial YJL102W MEF2 translation elongation factor, mitochondrial YJL133W MRS3 RNA splicing protein and member of the mitochondrial carrier family (MCF) YJL143W TIM17 mitochondrial inner membrane import translocase subunit YJL166W QCR8 ubiquinol--cytochrome-c reductase chain VIII YJL180C ATP12 F1F0-ATPase complex assembly protein YJL208C NUC1 nuclease, mitochondrial YJL209W CBP1 apo-cytochrome b pre-mRNA processing protein YJR016C ILV3 dihydroxy-acid dehydratase YJR034W PET191 involved in assembly of cytochrome oxidase YJR045C SSC1 mitochondrial heat shock protein 70-related protein YJR048W CYC1 cytochrome-c isoform 1 YJR051W OSM1 osmotic growth protein YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YJR095W SFC1 succinate-fumarate transporter YJR113C RSM7 similarity to bacterial, chloroplast and mitochondrial ribosomal protein S7 YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YJR135W-A TIM8 delivers Proteins across the intermembrane space of mitochondria to the TIM22 complex YJR144W MGM101 mitochondrial genome maintenance protein YKL003C MRP17 ribosomal protein of the small subunit, mitochondrial YKL011C CCE1 cruciform-cutting endonuclease, mitochondrial YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL029C MAE1 malic enzyme YKL085W MDH1 malate dehydrogenase precursor, mitochondrial YKL087C CYT2 holocytochrome-c1 synthase YKL106W AAT1 aspartate transaminase, mitochondrial YKL120W OAC1 similarity to mitochondrial uncoupling proteins (MCF) YKL134C OCT1 mitochondrial intermediate peptidase YKL138C MRPL31 ribosomal protein YmL31, mitochondrial YKL141W SDH3 cytochrome b560 subunit of respiratory complex II YKL142W MRP8 ribosomal protein, mitochondrial YKL148C SDH1 succinate dehydrogenase flavoprotein precursor YKL150W MCR1 cytochrome-b5 reductase YKL167C MRP49 ribosomal protein, mitochondrial YKL170W MRPL38 ribosomal protein of the large subunit (L14), mitochondrial YKL192C ACP1 mitochonrial acyl-carrier protein YKL194C MST1 threonine--tRNA ligase, mitochondrial YKL208W CBT1 apo-cytochrome b pre-mRNA processing protein YKR006C MRPL13 ribosomal protein YmL13, mitochondrial YKR052C MRS4 RNA splicing protein and member of the mitochondrial carrier family (MCF) YKR066C CCP1 cytochrome-c peroxidase precursor YKR085C MRPL20 ribosomal protein YmL20, mitochondrial YLL001W DNM1 dynamin-related protein YLL006W MMM1 required for mitochondrial shape and structure YLL009C COX17 interacts genetically with SCO1 and SCO2 in cytochrome oxidase assembly YLL041C SDH2 succinate dehydrogenase iron-sulfur protein subunit YLR038C COX12 cytochrome-c oxidase, subunit VIB YLR067C PET309 required for stability and translation of COX1 mRNA YLR069C MEF1 translation elongation factor G, mitochondrial YLR139C SLS1 suppresses lethality of SSM4 deletion YLR142W PUT1 proline oxidase YLR163C MAS1 mitochondrial processing peptidase YLR168C (MSF1) probably involved in intramitochondrial protein sorting YLR203C MSS51 possibly involved in translational activation of COX1 and COB mRNA YLR259C HSP60 heat shock protein - chaperone, mitochondrial YLR295C ATP14 F1F0-ATPase complex, subunit h YLR304C ACO1 aconitate hydratase YLR312W-A MRPL15 ribosomal protein of the large subunit, mitochondrial YLR348C DIC1 dicarboxylate carrier protein YLR355C ILV5 ketol-acid reducto-isomerase YLR369W SSQ1 mitochondrial heat shock protein 70 YLR382C NAM2 leucine--tRNA ligase precursor, mitochondrial YLR393W ATP10 F1F0 ATPase complex assembly protein YLR395C COX8 cytochrome-c oxidase chain VIII YLR439W MRPL4 ribosomal protein, mitochondrial YML009C MRPL39 60S ribosomal protein, mitochondrial YML021C UNG1 uracil-DNA glycosylase YML025C YML6 ribosomal protein, mitochondrial YML042W CAT2 carnitine O-acetyltransferase YML054C CYB2 lactate dehydrogenase cytochrome b2 YML061C PIF1 DNA helicase involved in mitochondrial DNA repair and telomere length YML078W CPR3 cyclophilin (peptidylprolyl isomerase), mitochondrial YML081C-A ATP18 gene for subunit i/j of the mitochondrial F1F0-ATP synthase YML091C RPM2 ribonuclease P precursor, mitochondrial YML110C COQ5 ubiquinone biosynthesis, methyltransferase YML120C NDI1 NADH-ubiquinone-6 oxidoreductase YML129C COX14 cytochrome-c oxidase assembly protein YMR023C MSS1 mitochondrial GTPase involved in expression of COX1 YMR024W MRPL3 ribosomal protein of the large subunit, mitochondrial YMR035W IMP2 mitochondrial inner membrane protease subunit YMR056C AAC1 ADP/ATP carrier protein (MCF) YMR060C TOM37 mitochondrial outer membrane import receptor subunit, 37 kD YMR062C ECM40 acetylornithine acetyltransferase YMR072W ABF2 high mobility group protein YMR083W ADH3 alcohol dehydrogenase III YMR089C YTA12 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YMR108W ILV2 acetolactate synthase YMR145C NDH1 mitochondrial cytosolically directed NADH dehydrogenase YMR150C IMP1 protease, mitochondrial YMR152W YIM1 mitochondrial inner membrane protease YMR177W MMT1 mitochondrial gene involved in iron uptake YMR189W GCV2 glycine decarboxylase P subunit YMR193W MRPL24 ribosomal protein of the large subunit, mitochondrial YMR203W TOM40 forms the hydrophilic channel of the mitochondrial import pore for preproteins YMR225C MRPL44 ribosomal protein YMR44, mitochondrial YMR228W MTF1 RNA polymerase specific factor, mitochondrial YMR241W YHM2 yeast suppressor gene of HM (mitochondrial histone) mutant (ABF2) YMR256C COX7 cytochrome-c oxidase, subunit VII YMR257C PET111 required for translation of COX2 mRNA YMR267W PPA2 inorganic pyrophosphatase, mitochondrial YMR282C AEP2 required for the expression of subunit-9 of atp synthase YMR286W MRPL33 ribosomal protein of the large subunit, mitochondrial YMR287C MSU1 3'-5' exonuclease for RNA 3' ss-tail, mitochondrial YMR301C ATM1 ATP-binding cassette transporter protein, mitochondrial YMR302C PRP12 involved in early maturation of pre-rRNA YNL005C MRP7 ribosomal protein YmL2 precursor, mitochondrial YNL037C IDH1 isocitrate dehydrogenase (NAD+) subunit 1, mitochondrial YNL052W COX5A cytochrome-c oxidase chain V.A precursor YNL055C POR1 mitochondrial outer membrane porin YNL070W TOM7 mitochondrial outer membrane import receptor subunit, 7 kD YNL071W LAT1 dihydrolipoamide S-acetyltransferase YNL073W MSK1 lysyl-tRNA synthetase, mitochondrial YNL104C LEU4 2-isopropylmalalate synthase YNL121C TOM70 mitochondrial outer membrane specialized import receptor YNL131W TOM22 mitochondrial outer membrane import receptor complex subunit YNL137C NAM9 ribosomal protein, mitochondrial YNL169C PSD1 phosphatidylserine decarboxylase 1 YNL185C MRPL19 ribosomal protein of the large subunit, mitochondrial YNL213C YNL213C similarity to hypothetical protein Neurospora crassa YNL252C MRPL17 ribosomal protein of the large subunit (YmL30), mitochondrial YNL284C MRPL10 ribosomal protein of the large subunit, mitochondrial YNL306W MRPS18 ribosomal protein of the small subunit, mitochondrial YNL315C ATP11 F1F0-ATPase complex assembly protein YNL328C MDJ2 heat shock protein - chaperone YNR001C CIT1 citrate (si)-synthase, mitochondrial YNR017W MAS6 mitochondrial inner membrane import translocase subunit YNR041C COQ2 para-hydroxybenzoate--polyprenyltransferase YNR045W PET494 translational activator, mitochondrial YOL009C MDM12 involved in mitochondrial inheritance YOL023W IFM1 translation initiation factor 2, mitochondrial YOL025W LAG2 involved in determining longevity YOL033W MSE1 glutamyl-tRNA synthetase, mitochondrial YOL059W GPD2 glycerol-3-phosphate dehydrogenase (NAD+), mitochondrial YOL077W-A ATP19 subunit K of the dimeric form of mitochondrial F1F0-ATP synthase YOL096C COQ3 enzyme of ubiquinone (coenzyme Q) biosynthesis YOL140W ARG8 acetylornithine aminotransferase YOR017W PET127 component of mitochondrial translation system YOR020C HSP10 chaperonin, mitochondrial YOR037W CYC2 cytochrome-c mitochondrial import factor YOR040W GLO4 glyoxalase II (hydroxyacylglutathione hydrolase) YOR045W TOM6 mitochondrial outer membrane import receptor subunit, 6 kD YOR065W CYT1 cytochrome-c1 YOR125C CAT5 involved in coenzyme Q (ubiquinone) biosynthesis YOR130C ORT1 ornithine transport protein of mitochondria involved in arginine metabolism, member of the mitochondrial carrier family (MCF) YOR136W IDH2 isocitrate dehydrogenase (NAD+) subunit 2, mitochondrial YOR150W MRPL23 ribosomal protein of the large subunit, mitochondrial YOR158W PET123 ribosomal protein, mitochondrial YOR176W HEM15 ferrochelatase precursor YOR187W TUF1 translation elongation factor TU, mitochondrial YOR196C LIP5 lipoic acid synthase YOR201C PET56 rRNA (guanosine-2'-O-)-methyltransferase YOR211C MGM1 dynamin-like protein YOR232W MGE1 heat shock protein - chaperone YOR274W MOD5 tRNA isopentenyltransferase YOR316C COT1 cobalt accumulation protein YOR330C MIP1 DNA-directed DNA polymerase gamma catalytic subunit, mitochondrial YOR334W MRS2 RNA splicing protein and member of the mitochondrial carrier family (MCF) YOR386W PHR1 deoxyribodipyrimidine photo-lyase YPL013C YPL013C strong similarity to N.crassa mitochondrial ribosomal protein S24 YPL029W SUV3 ATP-dependent RNA helicase, mitochondrial YPL040C ISM1 isoleucine--tRNA ligase, mitochondrial YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL097W MSY1 tyrosyl-tRNA synthetase YPL104W MSD1 aspartate--tRNA ligase, mitochondrial YPL118W MRP51 mitochondrial ribosomal protein of the small subunit YPL132W COX11 cytochrome-c oxidase assembly protein YPL172C COX10 farnesyl transferase YPL173W MRPL40 ribosomal protein of the large subunit (YmL40), mitochondrial YPL183W-A YPL183W-A strong similarity to mitochondrial and bacterial ribosomal L36 proteins YPL215W CBP3 required for assembly of cytochrome bc1 complex YPL224C MMT2 mitochondrial iron transporter YPL262W FUM1 fumarate hydratase YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPR001W CIT3 citrate (si)-synthase, mitochondrial YPR004C YPR004C strong similarity to electron transfer flavoproteins alpha chain YPR020W ATP20 subunit G of the dimeric form of mitochondrial F1F0-ATP Synthase YPR024W YME1 protease of the SEC18/CDC48/PAS1 family of ATPases (AAA) YPR037C ERV2 similarity to ERV1P and rat ALR protein YPR047W MSF1 phenylalanine--tRNA ligase alpha chain, mitochondrial YPR058W YMC1 mitochondrial carrier protein (MCF) YPR133W-A TOM5 mitochondrial outer membrane protein YPR134W MSS18 splicing protein YPR166C MRP2 ribosomal protein S14 YPR191W QCR2 ubiquinol--cytochrome-c reductase 40KD chain II Q0045 COX1 cytochrome-c oxidase subunit I Q0050 AI1 COX1 intron 1 protein Q0055 AI2 COX1 intron 2 protein Q0060 AI3 DNA endonuclease Q0065 AI4 DNA endonuclease Q0070 AI5_ALPHA DNA endonuclease AI5_ALPHA Q0075 AI5_BETA COX1 intron protein aI5-beta Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0105 COB ubiquinol-cytochrome-c reductase subunit (cytochrome B) Q0110 BI2 mRNA maturase BI2 Q0115 BI3 mRNA maturase BI3 Q0120 BI4 mRNA maturase BI4 Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 Q0140 VAR1 mitochondrial ribosomal protein Q0160 SCEI DNA endonuclease in 21S rRNA intron Q0250 COX2 cytochrome-c oxidase subunit II Q0275 COX3 cytochrome-c oxidase chain III peroxisome (39 ORFs) 40.19 39 YAL054C ACS1 acetyl-CoA synthetase YBR041W FAT1 very long-chain fatty acyl-CoA synthetase YBR204C YBR204C weak similarity to peroxisomal serine-active lipase YBR222C FAT2 AMP-binding protein, peroxisomal YCR005C CIT2 citrate (si)-synthase, peroxisomal YDL065C PEX19 required for biogenesis of peroxisomes - peroxin YDL078C MDH3 malate dehydrogenase, peroxisomal YDR142C PEX7 peroxisomal import protein - peroxin YDR244W PEX5 peroxisomal targeting signal receptor YDR256C CTA1 catalase A, peroxisomal YDR265W PEX10 peroxisomal assembly protein - peroxin YDR329C PEX3 peroxisomal assembly protein - peroxin YER015W FAA2 long-chain-fatty-acid--CoA ligase YGL153W PEX14 peroxisomal protein involved in protein import - peroxin YGL205W POX1 acyl-CoA oxidase YGR077C PEX8 similarity to Hansenula polymorpha PER1 protein and weak similarity to Pichia pastoris PER3 protein YGR133W PEX4 E2 ubiquitin-conjugating enzyme - peroxin YIL160C POT1 acetyl-CoA C-acyltransferase, peroxisomal YIR031C DAL7 malate synthase 2 YJL210W PEX2 peroxisomal assembly protein - peroxin YJR019C TES1 thioesterase, peroxisomal YKL188C PXA2 ABC transporter, peroxisomal YKR009C FOX2 hydratase-dehydrogenase-epimerase, peroxisomal YLR027C AAT2 aspartate aminotransferase, cytosolic YLR109W AHP1 Alkyl hydroperoxide reductase YLR191W PEX13 peroxisomal protein involved in protein import - peroxin YLR251W YLR251W similarity to peroxisomal rat membrane protein PMP22 YLR284C ECI1 delta3-cis-delta2-trans-enoyl-CoA isomerase YML042W CAT2 carnitine O-acetyltransferase YMR026C PEX12 required for biogenesis of peroxisomes - peroxin YNL009W IDP3 isocitrate dehydrogenase, NADP-dependent YNL117W MLS1 malate synthase 1 YNL202W SPS19 peroxisomal 2,4-dienoyl-CoA reductase YNL214W PEX17 component of the peroxisomal protein translocation - peroxin YNL329C PEX6 peroxisomal assembly protein YOL044W PEX15 required for peroxisome assembly - peroxin YOL147C PEX11 peroxisomal membrane protein - peroxin YOR180C DCI1 Enoyl-CoA Hydratase, peroxisomal YPL147W PXA1 long-chain fatty acid transporter endosome (12 ORFs) 40.22 12 YDR107C YDR107C strong similarity to EMP70 protein YDR313C PIB1 phosphatidylinositol(3)-phosphate binding protein YDR323C PEP7 vacuolar segregation protein YDR468C TLG1 member of the syntaxin family of t-SNAREs YGL095C VPS45 vacuolar protein sorting-associated protein YJL154C VPS35 protein-sorting protein, vacuolar YKL041W VPS24 endosomal Vps protein complex subunit YLR083C EMP70 endosomal protein YLR309C IMH1 involved in vesicular transport YNR006W VPS27 vacuolar protein sorting-associated protein YOL018C TLG2 member of the syntaxin family of t-SNAREs YPR173C VPS4 vacuolar sorting protein vacuole or lysosome (59 ORFs) 40.25 59 YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YBR217W APG12 component of the autophagic system YBR286W APE3 vacuolar aminopeptidase Y YCR044C PER1 involved in manganese homeostasis YDL077C VAM6 vacuolar carboxypeptidase Y YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDL149W APG9 integral membrane protein required for Cvt and autophagy transport YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDR080W VPS41 required for the vacuolar assembly YDR135C YCF1 glutathione S-conjugate transporter, vacuolar YDR323C PEP7 vacuolar segregation protein YDR468C TLG1 member of the syntaxin family of t-SNAREs YDR481C PHO8 repressible alkaline phosphatase vacuolar YDR495C VPS3 vacuolar sorting protein YEL013W VAC8 required for vacuole inheritance and protein targeting from the cytoplasm to vacuole YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YEL060C PRB1 protease B, vacuolar YGL006W PMC1 Ca2+-transporting P-type ATPase YGL095C VPS45 vacuolar protein sorting-associated protein YGL156W AMS1 alpha-mannosidase YGL212W VAM7 vacuolar morphogenesis protein YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YHR026W PPA1 H+-ATPase 23 KD subunit, vacuolar YHR028C DAP2 dipeptidyl aminopeptidase B YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YHR171W APG7 component of the autophagic system YIL099W SGA1 sporulation specific glucan 1,4-alpha-glucosidase YJL053W PEP8 vacuolar protein sorting/targeting protein YJL154C VPS35 protein-sorting protein, vacuolar YJL172W CPS1 Gly-X carboxypeptidase YSCS precursor YKL002W DID4 class E vacuolar-protein sorting and endocytosis factor YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL103C LAP4 aminopeptidase yscI precursor, vacuolar YKL203C TOR2 phosphatidylinositol 3-kinase YKR035W-A DID2 class E vacuolar-protein sorting and endocytosis factor YLL048C YBT1 yeast bile transporter YLR025W SNF7 class E Vps protein YLR034C SMF3 strong similarity to SMF2 protein and S.pombe hypothetical protein YLR093C NYV1 v-SNARE, vacuolar YLR148W PEP3 vacuolar membrane protein YLR309C IMH1 involved in vesicular transport YLR396C VPS33 vacuolar sorting protein YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YMR231W PEP5 vacuolar biogenesis protein YMR297W PRC1 carboxypeptidase y, serine-type protease YNL054W VAC7 vacuolar protein YOL018C TLG2 member of the syntaxin family of t-SNAREs YOR036W PEP12 syntaxin (T-SNARE), vacuolar YOR106W VAM3 syntaxin (t-SNARE) YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YPL045W VPS16 vacuolar sorting protein YPL149W APG5 involved in autophagy and nutrient starvation YPL154C PEP4 aspartyl protease YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPR026W ATH1 acid trehalase, vacuolar YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar extracellular / secretion proteins (20 ORFs) 40.27 20 YAR071W PHO11 secreted acid phosphatase YBR092C PHO3 constitutive acid phosphatase precursor YDR461W MFA1 mating pheromone a-factor 1 YGL032C AGA2 a-agglutinin binding subunit YGL089C MF(ALPHA)2 mating pheromone alpha-2 factor YHR215W PHO12 secreted acid phosphatase YIL015W BAR1 barrierpepsin precursor YIL162W SUC2 invertase (sucrose hydrolyzing enzyme) YIR019C MUC1 extracellular alpha-1,4-glucan glucosidase YJL159W HSP150 member of the PIR1P/HSP150P/PIR3P family YJL174W KRE9 cell wall synthesis protein YKL157W APE2 aminopeptidase yscII YKR102W FLO10 similarity to FLO1P YLR250W SSP120 secretory protein YLR286C CTS1 endochitinase YLR300W EXG1 exo-beta-1,3-glucanase (I/II), major isoform YNL145W MFA2 mating pheromone a-factor 2 YNL160W YGP1 secreted glycoprotein YNL322C KRE1 cell wall protein YPL187W MFALPHA1 mating pheromone alpha-1 precursor prokaryotic cell membrane (inner membrane of gram - bacteria) (1 ORF) 40.30 1 YER072W VTC1 Negative Regulator of Cdc Fourty two (CDC42) other subcellular localisation (8 ORFs) 40.99 8 YBR041W FAT1 very long-chain fatty acyl-CoA synthetase YDL052C SLC1 fatty acyltransferase YDL161W ENT1 clathrin binding protein, required for endocytosis YDR027C LUV1 interacts with the beta-tubulin binding protein RBL2P YER026C CHO1 CDP-diacylglycerol serine O-phosphatidyltransferase YGR175C ERG1 squalene monooxygenase YLR206W ENT2 clathrin binding protein, required for endocytosis YML008C ERG6 S-adenosyl-methionine delta-24-sterol-c-methyltransferase PROTEIN ACTIVITY REGULATION (13 ORFs) 62 13 YAL041W CDC24 GTP/GDP exchange factor for CDC42P YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBR140C IRA1 inhibitory regulator protein of the ras-cyclic AMP pathway YBR195C MSI1 chromatin assembly complex, subunit p50 YDL135C RDI1 rho GDP dissociation inhibitor with activity toward RHO1P YDR183W PLP1 Phosducin homologue likely to be involved in regulation of pheromone response YFL047W RGD2 GTPase activating protein YGR070W ROM1 GDP/GTP exchange protein for RHO1P YLL016W SDC25 GDP/GTP exchange factor (GEF) YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR371W ROM2 GDP/GTP exchange factor for RHO1P YOR107W RGS2 negative regulator of glucose-induced cAMP signaling pathway YPL115C BEM3 GTPase-activating protein for CDC42P and RHO1P target of regulation (13 ORFs) 62.02 13 YAL041W CDC24 GTP/GDP exchange factor for CDC42P YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBR140C IRA1 inhibitory regulator protein of the ras-cyclic AMP pathway YBR195C MSI1 chromatin assembly complex, subunit p50 YDL135C RDI1 rho GDP dissociation inhibitor with activity toward RHO1P YDR183W PLP1 Phosducin homologue likely to be involved in regulation of pheromone response YFL047W RGD2 GTPase activating protein YGR070W ROM1 GDP/GTP exchange protein for RHO1P YLL016W SDC25 GDP/GTP exchange factor (GEF) YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR371W ROM2 GDP/GTP exchange factor for RHO1P YOR107W RGS2 negative regulator of glucose-induced cAMP signaling pathway YPL115C BEM3 GTPase-activating protein for CDC42P and RHO1P regulator of G-protein signalling (13 ORFs) 62.02.05 13 YAL041W CDC24 GTP/GDP exchange factor for CDC42P YBL016W FUS3 mitogen-activated protein kinase (MAP kinase) YBR140C IRA1 inhibitory regulator protein of the ras-cyclic AMP pathway YBR195C MSI1 chromatin assembly complex, subunit p50 YDL135C RDI1 rho GDP dissociation inhibitor with activity toward RHO1P YDR183W PLP1 Phosducin homologue likely to be involved in regulation of pheromone response YFL047W RGD2 GTPase activating protein YGR070W ROM1 GDP/GTP exchange protein for RHO1P YLL016W SDC25 GDP/GTP exchange factor (GEF) YLR310C CDC25 GDP/GTP exchange factor for RAS1P and RAS2P YLR371W ROM2 GDP/GTP exchange factor for RHO1P YOR107W RGS2 negative regulator of glucose-induced cAMP signaling pathway YPL115C BEM3 GTPase-activating protein for CDC42P and RHO1P PROTEIN WITH BINDING FUNCTION OR COFACTOR REQUIREMENT (structural or catalytic) (4 ORFs) 63 4 YDL235C YPD1 phosphorelay intermediate between SLN1P and SSK1P YHR001W OSH7 similarity to KES1P YIL147C SLN1 two-component signal transducer YLR006C SSK1 two-component signal transducer protein binding (3 ORFs) 63.01 3 YDL235C YPD1 phosphorelay intermediate between SLN1P and SSK1P YIL147C SLN1 two-component signal transducer YLR006C SSK1 two-component signal transducer lipid binding (1 ORF) 63.09 1 YHR001W OSH7 similarity to KES1P TRANSPORT FACILITATION (313 ORFs) 67 313 YAL026C DRS2 P-type amino-phospholipids-ATPase YAL067C SEO1 suppressor of sulfoxyde ethionine resistance YAR035W YAT1 carnitine acetyltransferase, mitochondrial YBL011W SCT1 suppresses a choline-transport mutant YBL030C PET9 ADP/ATP carrier protein (MCF) YBL089W YBL089W weak similarity to A.thaliana aminoacid permease AAP3 YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBR008C FLR1 fluconazole resistance protein YBR021W FUR4 uracil permease YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR043C YBR043C similarity to benomyl/methotrexate resistance protein YBR052C YBR052C strong similarity to S.pombe brefeldin A resistance protein obr1 YBR068C BAP2 leucine permease, high-affinity (S1) YBR069C TAT1 amino acid permease YBR085W AAC3 ADP/ATP carrier protein (MCF) YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YBR132C AGP2 amino-acid permease YBR171W SEC66 ER protein-translocation complex subunit YBR180W DTR1 dityrosine transporter YBR192W RIM2 mitochondrial carrier protein (MCF) YBR207W FTH1 similarity to Iron permease FTR1P (YER145c) YBR235W YBR235W similarity to bumetanide-sensitive Na-K-Cl cotransport protein YBR241C YBR241C similarity to glucose transport proteins YBR291C CTP1 citrate transport protein, mitochondrial (MCF) YBR293W YBR293W similarity to multidrug resistance proteins YBR294W SUL1 high-affinity sulfate transport protein YBR295W PCA1 P-type Cu2+-transporting ATPase YBR296C PHO89 Na+-coupled phosphate transport protein, high affinity YBR298C MAL31 maltose permease YCL025C AGP1 asparagine and glutamine permease YCL038C YCL038C similarity to bacterial membrane transporter YCL069W YCL069W strong similarity to drug resistance protein SGE1 YCL073C YCL073C strong similarity to subtelomeric encoded proteins YCR011C ADP1 ATP-dependent permease YCR017C CWH43 putative sensor/transporter protein YCR023C YCR023C weak similarity to E.coli tetracycline resistance protein TCR1 YCR024C-A PMP1 H+-ATPase subunit, plasma membrane YCR028C FEN2 high affinity H+/pantothenate symporter YCR037C PHO87 member of the phosphate permease family YCR098C GIT1 glycerophosphoinositol transporter YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDL138W RGT2 suppressor of SNF3 mutant YDL149W APG9 integral membrane protein required for Cvt and autophagy transport YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL198C YHM1 member of the mitochondrial carrier family (MCF) YDL199C YDL199C similarity to sugar transporter proteins YDL206W YDL206W weak similarity to transporter proteins YDL210W UGA4 GABA-specific high-affinity permease YDL217C TIM22 subunit of the TIM22-complex YDL245C HXT15 strong similarity to HXT17P and HXT7P YDL247W YDL247W strong similarity to sugar transport proteins YDR011W SNQ2 multidrug resistance protein YDR038C ENA5 P-type ATPase involved in Na+ efflux YDR039C ENA2 P-type ATPase involved in Na+ efflux YDR040C ENA1 P-type ATPase involved in Na+ and Li+ efflux YDR046C BAP3 valine transporter YDR086C SSS1 ER protein-translocase complex subunit YDR091C RLI1 strong similarity to human RNase L inhibitor and M.jannaschii ABC transporter protein YDR093W YDR093W similarity to P.falciparum ATPase 2 YDR119W YDR119W similarity to B.subtilis tetracyclin resistance YDR135C YCF1 glutathione S-conjugate transporter, vacuolar YDR270W CCC2 probable copper-transporting ATPase YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR322C-A TIM11 subunit E of the dimeric form of mitochondrial F1F0-ATPase YDR342C HXT7 high-affinity hexose transporter YDR343C HXT6 high-affinity hexose transporter YDR345C HXT3 low-affinity hexose transporter YDR375C BCS1 mitochondrial protein of the CDC48/PAS1/SEC18 (AAA) family of ATPases YDR387C YDR387C similarity to ITR1P and ITR2P and E.coli araE YDR406W PDR15 ATP-binding cassette transporter family member YDR456W NHX1 NA+-H+ antiporter YDR497C ITR1 myo-inositol permease, major YDR508C GNP1 high-affinity glutamine permease YDR536W STL1 member of the sugar permease family YEL004W YEA4 strong similarity to K.lactis golgi uridine diphosphate-N-acetylglucosamine transporter YEL006W YEL006W similarity to peroxisomal membrane and mitochondrial carrier proteins YEL017C-A PMP2 H+-ATPase subunit, plasma membrane YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL031W SPF1 P-type ATPase YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YEL063C CAN1 amino acid permease YEL064C YEL064C similarity to YBL089w YEL065W SIT1 probable multidrug resistance protein YEL069C HXT13 high-affinity hexose transporter YER019C-A SBH2 ER protein-translocation complex subunit YER024W YAT2 carnitine O-acetyltransferase YER036C KRE30 strong similarity to members of the ABC transporter family YER053C YER053C strong similarity to mitochondrial phosphate carrier protein YER056C FCY2 purine-cytosine permease YER060W FCY21 purine-cytosine permease YER060W-A FCY22 purine/cytosine permease with similarity to FCY2P YER087C-B SBH1 involved in translocation into the ER YER119C YER119C weak similarity to E.herbicola tyrosine permease YER145C FTR1 iron permease that mediates high-affinity iron uptake YER166W YER166W similarity to ATPase P.falciparum ATPase 2 YFL011W HXT10 hexose transporter YFL040W YFL040W similarity to yeast glucose transport proteins YFL041W FET5 multicopy oxidase YFL050C ALR2 divalent cation transprter YFL054C YFL054C similarity to channel proteins YFL055W AGP3 amino acid permease YFR009W GCN20 positive effector of GCN2P YFR045W YFR045W similarity to mitochondrial citrate transport proteins YGL006W PMC1 Ca2+-transporting P-type ATPase YGL008C PMA1 H+-transporting P-type ATPase, major isoform, plasma membrane YGL077C HNM1 choline permease YGL084C GUP1 similarity to GUP2P - putative glycerol transporter YGL104C YGL104C similarity to glucose transport proteins YGL167C PMR1 Ca2+-transporting P-type ATPase YGL186C YGL186C similarity to hypothetical protein FCY21P and weak similarity to FCY2 protein YGL225W GOG5 GDP-mannose transporter into the lumen of the Golgi YGL255W ZRT1 high-affinity zinc transport protein YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YGR055W MUP1 high affinity methionine permease YGR065C VHT1 plasma membrane H+-biotin symporter YGR082W TOM20 mitochondrial outer membrane import receptor subunit, 20 kD YGR096W YGR096W hypothetical mitochondrial transport protein YGR121C MEP1 ammonia permease of high capacity and moderate affinity YGR138C TPO2 polyamine transport protein YGR191W HIP1 histidine permease YGR197C SNG1 involved in nitroguanidine resistance YGR217W CCH1 calcium channel protein YGR224W AZR1 strong similarity to drug resistance protein SGE1, YKR105c and YCL069W YGR260W TNA1 similarity to allantoate transport protein YGR281W YOR1 ATP-binding cassette transporter protein YGR289C MAL11 general alpha-glucoside permease YHL016C DUR3 urea transport protein YHL035C YHL035C similarity to multidrug resistance proteins YHL036W MUP3 very low affinity methionine permease YHL040C ARN1 ferrichrome-type siderophore transporter YHL047C TAF1 siderophore transporter for triacetylfusarinine C YHR002W YHR002W similarity to bovine mitochondrial carrier protein/Grave's disease carrier protein YHR026W PPA1 H+-ATPase 23 KD subunit, vacuolar YHR032W ERC1 ethionine resistance protein YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YHR048W YHR048W similarity to multidrug resistance proteins YHR092C HXT4 moderate- to low-affinity glucose transporter YHR094C HXT1 low-affinity hexose transporter YHR096C HXT5 member of the hexose transporter family YHR175W CTR2 copper transport protein YIL006W YIL006W similarity to FLX1P YIL013C PDR11 membrane transporter YIL022W TIM44 mitochondrial inner membrane import receptor subunit YIL048W NEO1 ATPase whose overproduction confers neomycin resistance YIL056W YIL056W similarity to YER064c YIL088C YIL088C weak similarity to A.thaliana aminoacid permease AAP4 YIL114C POR2 voltage dependent anion channel (YVDAC2) YIL120W QDR1 similarity to antibiotic resistance proteins YIL121W YIL121W similarity to antibiotic resistance proteins YIL134W FLX1 FAD carrier protein (MCF), mitochondrial YIL166C YIL166C similarity to allantoate permease DAL5P YIL170W HXT12 strong similarity to sugar transport proteins YIL171W HXT12 strong similarity to sugar transport proteins YIR028W DAL4 allantoin permease YJL034W KAR2 nuclear fusion protein YJL054W TIM54 translocase for the insertion of proteins into the mitochondrial inner membrane YJL093C TOK1 outward-rectifier potassium channel YJL094C KHA1 K+/H+ exchanger YJL117W PHO86 inorganic phospate transporter YJL129C TRK1 potassium transport protein TRK1P, high-affinity YJL143W TIM17 mitochondrial inner membrane import translocase subunit YJL198W PHO90 low affinity phosphate transporter YJL212C OPT1 oligopeptide transporter specific for tetra- and pentapeptides YJL214W HXT8 hexose transport protein YJL219W HXT9 hexose transport protein YJR001W YJR001W weak similarity to A.thaliana aminoacid permease AAP4 YJR040W GEF1 voltage-gated chloride channel protein YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YJR095W SFC1 succinate-fumarate transporter YJR106W ECM27 involved in cell wall biogenesis and architecture YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YJR124C YJR124C weak similarity to Staphylococcus multidrug resistance protein YJR152W DAL5 allantoate permease YJR158W HXT16 member of the hexose transporter family of the major facilitator superfamily [MFS] YJR160C YJR160C strong similarity to MAL31P YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL120W OAC1 similarity to mitochondrial uncoupling proteins (MCF) YKL146W YKL146W strong similarity to S.pombe hypothetical protein C3H1.09C YKL174C YKL174C similarity to choline transport protein HNM1P YKL175W ZRT3 vacuolar membrane protein involved in the regulation of zinc storage YKL188C PXA2 ABC transporter, peroxisomal YKL192C ACP1 mitochonrial acyl-carrier protein YKL209C STE6 ATP-binding cassette transporter protein YKL217W JEN1 carboxylic acid transporter protein YKL221W YKL221W weak similarity to human X-linked PEST-containing transporter YKR039W GAP1 general amino acid permease YKR050W TRK2 moderate-affinity potassium transport protein YKR067W GPT2 strong similarity to SCT1P YKR093W PTR2 peptide transporter YKR103W YKR103W similarity to multidrug resistance proteins YKR104W YKR104W similarity to multidrug resistance proteins YKR105C YKR105C strong similarity to SGE1P and hypothetical protein YCL069w YKR106W YKR106W strong similarity to subtelomeric encoded proteins YLL015W BPT1 similarity to YCF1P, YOR1P, rat organic anion transporter YLL027W ISA1 mitochondrial protein required for normal iron metabolism YLL028W TPO1 polyamine transport protein YLL043W FPS1 glycerol channel protein YLL048C YBT1 yeast bile transporter YLL052C AQY2 strong similarity to AQY1 YLL053C YLL053C similarity to water channel proteins YLL055W YLL055W similarity to DAL5P YLL061W MMP1 high affinity S-methylmethionine permease YLR004C YLR004C similarity to allantoate transport protein YLR081W GAL2 galactose (and glucose) permease YLR092W SUL2 sulfate transporter YLR130C ZRT2 low affininty zinc transporter YLR138W NHA1 putative Na+/H+ antiporter YLR188W MDL1 ATP-binding cassette transporter family member YLR237W THI7 thiamin transport protein YLR292C SEC72 ER protein-translocation complex subunit YLR295C ATP14 F1F0-ATPase complex, subunit h YLR341W SPO77 probably ATP-powered Ca2+ pump, possible role in sporulation YLR348C DIC1 dicarboxylate carrier protein YLR378C SEC61 ER protein-translocation complex subunit YLR411W CTR3 copper transport protein YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YML116W ATR1 aminotriazole and 4-nitroquinoline resistance protein YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YMR011W HXT2 high-affinity hexose transporter YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YMR056C AAC1 ADP/ATP carrier protein (MCF) YMR058W FET3 cell surface ferroxidase, high affinity YMR060C TOM37 mitochondrial outer membrane import receptor subunit, 37 kD YMR088C YMR088C similarity to multidrug resistance proteins YMR123W PKR1 resistance against Pichia farinosa killer toxin (SMK toxin) when expressed by a multi copy plasmid YMR162C YMR162C similarity to ATPases YMR203W TOM40 forms the hydrophilic channel of the mitochondrial import pore for preproteins YMR243C ZRC1 zinc- and cadmium resistance protein YMR279C YMR279C strong similarity to aminotriazole resistance protein YMR301C ATM1 ATP-binding cassette transporter protein, mitochondrial YMR319C FET4 low affinity Fe(II) iron transport protein YNL003C PET8 member of the mitochondrial carrier (MCF) family YNL014W HEF3 translation elongation factor eEF3 homolog YNL055C POR1 mitochondrial outer membrane porin YNL065W AQR1 similarity to resistance proteins YNL070W TOM7 mitochondrial outer membrane import receptor subunit, 7 kD YNL121C TOM70 mitochondrial outer membrane specialized import receptor YNL125C ESBP6 similarity to YKL221w and human X-linked PEST-containing transporter YNL131W TOM22 mitochondrial outer membrane import receptor complex subunit YNL142W MEP2 high affinity low capacity ammonia permease YNL259C ATX1 antioxidant protein and metal homeostasis factor YNL268W LYP1 lysine-specific high-affinity permease YNL270C ALP1 high-affinity permease for basic amino acids YNL318C HXT14 hexose transport protein YNR013C PHO91 similarity to PHO87P and PHO90P YNR017W MAS6 mitochondrial inner membrane import translocase subunit YNR039C ZRG17 weak similarity to Anopheles mitochondrial NADH dehydrogenase subunit 2 YNR055C HOL1 member of major facilitator superfamily multidrug-resistance protein subfamily 1 YNR056C BIO5 similarity to choline transport protein HNM1P YNR070W YNR070W strong similarity to SNQ2P YNR072W HXT17 sugar transport protein YOL020W TAT2 high affinity tryptophan transport protein YOL075C YOL075C similarity to A.gambiae ATP-binding-cassette protein YOL103W ITR2 myo-inositol permease, minor YOL119C YOL119C similarity to monocarboxylate transporter proteins YOL122C SMF1 manganese transporter YOL130W ALR1 divalent cation transporter YOL156W HXT11 low affinity glucose transport protein YOL158C ENB1 a gene of the major facilitator superfamily encodes a transporter for enterobactin YOL163W YOL163W similarity to P. putida phthalate transporter YOR011W AUS1 strong similarity to ATP-dependent permeases YOR035C SHE4 required for mother cell-specific gene expression YOR045W TOM6 mitochondrial outer membrane import receptor subunit, 6 kD YOR071C YOR071C strong similarity to Thi10p YOR130C ORT1 ornithine transport protein of mitochondria involved in arginine metabolism, member of the mitochondrial carrier family (MCF) YOR153W PDR5 pleiotropic drug resistance protein YOR192C YOR192C strong similarity to Thi10p YOR222W ODC2 similarity to ADP/ATP carrier proteins YOR254C SEC63 ER protein-translocation complex subunit YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR271C YOR271C strong similarity to Rattus tricarboxylate carrier YOR273C TPO4 polyamine transporter YOR291W YOR291W similarity to cation translocating ATPases YOR306C YOR306C similarity to human X-linked PEST-containing transporter YOR316C COT1 cobalt accumulation protein YOR328W PDR10 member of ATP-binding cassette (ABC) superfamily YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YOR348C PUT4 proline and gamma-aminobutyrate permease YOR378W YOR378W strong similarity to aminotriazole resistance protein YPL036W PMA2 H+-transporting P-type ATPase, minor isoform, plasma membrane YPL058C PDR12 multidrug resistance transporter YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL094C SEC62 ER protein-translocation complex subunit YPL134C ODC1 similarity to ADP,ATP carrier proteins YPL147W PXA1 long-chain fatty acid transporter YPL176C SSP134 similarity to chinese hamster transferrin receptor protein YPL189W GUP2 putative glycerol transporter involved in active glycerol uptake YPL224C MMT2 mitochondrial iron transporter YPL226W NEW1 similarity to translation elongation factor eEF3 YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPL265W DIP5 dicarboxylic amino acid permease YPL270W MDL2 ATP-binding cassette (ABC) transporter family member YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPL274W SAM3 high affinity S-adenosylmethionine permease YPR003C YPR003C similarity to sulphate transporter proteins YPR011C YPR011C similarity to ADP/ATP carrier proteins and Graves disease carrier protein YPR021C YPR021C similarity to human citrate transporter protein YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar YPR058W YMC1 mitochondrial carrier protein (MCF) YPR124W CTR1 copper transport protein YPR138C MEP3 low affinity high capacity ammonium permease YPR156C TPO3 polyamine transporter YPR192W AQY1 similarity to plasma membrane and water channel proteins YPR194C OPT2 similarity to S.pombe isp4 protein YPR198W SGE1 drug resistance protein YPR201W ARR3 involved in arsenite transport Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 channel / pore class transporters (6 ORFs) 67.01 6 YGR217W CCH1 calcium channel protein YIL114C POR2 voltage dependent anion channel (YVDAC2) YJL093C TOK1 outward-rectifier potassium channel YLL052C AQY2 strong similarity to AQY1 YLL053C YLL053C similarity to water channel proteins YPR192W AQY1 similarity to plasma membrane and water channel proteins ion channels (6 ORFs) 67.01.01 6 YGR217W CCH1 calcium channel protein YIL114C POR2 voltage dependent anion channel (YVDAC2) YJL093C TOK1 outward-rectifier potassium channel YLL052C AQY2 strong similarity to AQY1 YLL053C YLL053C similarity to water channel proteins YPR192W AQY1 similarity to plasma membrane and water channel proteins ion transporters (79 ORFs) 67.04 79 YAL026C DRS2 P-type amino-phospholipids-ATPase YAL067C SEO1 suppressor of sulfoxyde ethionine resistance YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YBR207W FTH1 similarity to Iron permease FTR1P (YER145c) YBR235W YBR235W similarity to bumetanide-sensitive Na-K-Cl cotransport protein YBR291C CTP1 citrate transport protein, mitochondrial (MCF) YBR294W SUL1 high-affinity sulfate transport protein YBR295W PCA1 P-type Cu2+-transporting ATPase YBR296C PHO89 Na+-coupled phosphate transport protein, high affinity YCR024C-A PMP1 H+-ATPase subunit, plasma membrane YCR037C PHO87 member of the phosphate permease family YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDR011W SNQ2 multidrug resistance protein YDR270W CCC2 probable copper-transporting ATPase YDR456W NHX1 NA+-H+ antiporter YEL017C-A PMP2 H+-ATPase subunit, plasma membrane YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL031W SPF1 P-type ATPase YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YEL065W SIT1 probable multidrug resistance protein YER053C YER053C strong similarity to mitochondrial phosphate carrier protein YER145C FTR1 iron permease that mediates high-affinity iron uptake YFL041W FET5 multicopy oxidase YFL050C ALR2 divalent cation transprter YGL006W PMC1 Ca2+-transporting P-type ATPase YGL008C PMA1 H+-transporting P-type ATPase, major isoform, plasma membrane YGL167C PMR1 Ca2+-transporting P-type ATPase YGL255W ZRT1 high-affinity zinc transport protein YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YGR065C VHT1 plasma membrane H+-biotin symporter YGR121C MEP1 ammonia permease of high capacity and moderate affinity YGR191W HIP1 histidine permease YHL016C DUR3 urea transport protein YHR026W PPA1 H+-ATPase 23 KD subunit, vacuolar YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YHR175W CTR2 copper transport protein YJL094C KHA1 K+/H+ exchanger YJL117W PHO86 inorganic phospate transporter YJL129C TRK1 potassium transport protein TRK1P, high-affinity YJL198W PHO90 low affinity phosphate transporter YJR040W GEF1 voltage-gated chloride channel protein YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL120W OAC1 similarity to mitochondrial uncoupling proteins (MCF) YKL175W ZRT3 vacuolar membrane protein involved in the regulation of zinc storage YKR050W TRK2 moderate-affinity potassium transport protein YLR092W SUL2 sulfate transporter YLR130C ZRT2 low affininty zinc transporter YLR138W NHA1 putative Na+/H+ antiporter YLR341W SPO77 probably ATP-powered Ca2+ pump, possible role in sporulation YLR348C DIC1 dicarboxylate carrier protein YLR411W CTR3 copper transport protein YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YMR058W FET3 cell surface ferroxidase, high affinity YMR243C ZRC1 zinc- and cadmium resistance protein YMR319C FET4 low affinity Fe(II) iron transport protein YNL142W MEP2 high affinity low capacity ammonia permease YNL259C ATX1 antioxidant protein and metal homeostasis factor YNR013C PHO91 similarity to PHO87P and PHO90P YNR039C ZRG17 weak similarity to Anopheles mitochondrial NADH dehydrogenase subunit 2 YOL122C SMF1 manganese transporter YOL130W ALR1 divalent cation transporter YOR153W PDR5 pleiotropic drug resistance protein YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR316C COT1 cobalt accumulation protein YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YPL036W PMA2 H+-transporting P-type ATPase, minor isoform, plasma membrane YPL176C SSP134 similarity to chinese hamster transferrin receptor protein YPL224C MMT2 mitochondrial iron transporter YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPR003C YPR003C similarity to sulphate transporter proteins YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar YPR124W CTR1 copper transport protein YPR138C MEP3 low affinity high capacity ammonium permease YPR201W ARR3 involved in arsenite transport cation transporters (62 ORFs) 67.04.01 62 YAL026C DRS2 P-type amino-phospholipids-ATPase YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YBR207W FTH1 similarity to Iron permease FTR1P (YER145c) YBR235W YBR235W similarity to bumetanide-sensitive Na-K-Cl cotransport protein YBR295W PCA1 P-type Cu2+-transporting ATPase YCR024C-A PMP1 H+-ATPase subunit, plasma membrane YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDR011W SNQ2 multidrug resistance protein YDR270W CCC2 probable copper-transporting ATPase YDR456W NHX1 NA+-H+ antiporter YEL017C-A PMP2 H+-ATPase subunit, plasma membrane YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL031W SPF1 P-type ATPase YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YEL065W SIT1 probable multidrug resistance protein YER145C FTR1 iron permease that mediates high-affinity iron uptake YFL041W FET5 multicopy oxidase YFL050C ALR2 divalent cation transprter YGL006W PMC1 Ca2+-transporting P-type ATPase YGL008C PMA1 H+-transporting P-type ATPase, major isoform, plasma membrane YGL167C PMR1 Ca2+-transporting P-type ATPase YGL255W ZRT1 high-affinity zinc transport protein YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YGR065C VHT1 plasma membrane H+-biotin symporter YGR121C MEP1 ammonia permease of high capacity and moderate affinity YGR191W HIP1 histidine permease YHL016C DUR3 urea transport protein YHR026W PPA1 H+-ATPase 23 KD subunit, vacuolar YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YHR175W CTR2 copper transport protein YJL094C KHA1 K+/H+ exchanger YJL129C TRK1 potassium transport protein TRK1P, high-affinity YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKR050W TRK2 moderate-affinity potassium transport protein YLR130C ZRT2 low affininty zinc transporter YLR138W NHA1 putative Na+/H+ antiporter YLR341W SPO77 probably ATP-powered Ca2+ pump, possible role in sporulation YLR411W CTR3 copper transport protein YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YMR058W FET3 cell surface ferroxidase, high affinity YMR243C ZRC1 zinc- and cadmium resistance protein YMR319C FET4 low affinity Fe(II) iron transport protein YNL142W MEP2 high affinity low capacity ammonia permease YNL259C ATX1 antioxidant protein and metal homeostasis factor YNR039C ZRG17 weak similarity to Anopheles mitochondrial NADH dehydrogenase subunit 2 YOL122C SMF1 manganese transporter YOL130W ALR1 divalent cation transporter YOR153W PDR5 pleiotropic drug resistance protein YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR316C COT1 cobalt accumulation protein YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YPL036W PMA2 H+-transporting P-type ATPase, minor isoform, plasma membrane YPL176C SSP134 similarity to chinese hamster transferrin receptor protein YPL224C MMT2 mitochondrial iron transporter YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar YPR124W CTR1 copper transport protein YPR138C MEP3 low affinity high capacity ammonium permease YPR201W ARR3 involved in arsenite transport heavy metal ion transporters (Cu, Fe, etc.) (23 ORFs) 67.04.01.01 23 YBR207W FTH1 similarity to Iron permease FTR1P (YER145c) YBR295W PCA1 P-type Cu2+-transporting ATPase YDR270W CCC2 probable copper-transporting ATPase YEL065W SIT1 probable multidrug resistance protein YER145C FTR1 iron permease that mediates high-affinity iron uptake YFL041W FET5 multicopy oxidase YFL050C ALR2 divalent cation transprter YGL255W ZRT1 high-affinity zinc transport protein YGR191W HIP1 histidine permease YHR175W CTR2 copper transport protein YLR130C ZRT2 low affininty zinc transporter YLR411W CTR3 copper transport protein YMR058W FET3 cell surface ferroxidase, high affinity YMR243C ZRC1 zinc- and cadmium resistance protein YMR319C FET4 low affinity Fe(II) iron transport protein YNL259C ATX1 antioxidant protein and metal homeostasis factor YNR039C ZRG17 weak similarity to Anopheles mitochondrial NADH dehydrogenase subunit 2 YOL122C SMF1 manganese transporter YOL130W ALR1 divalent cation transporter YOR316C COT1 cobalt accumulation protein YPL176C SSP134 similarity to chinese hamster transferrin receptor protein YPR124W CTR1 copper transport protein YPR201W ARR3 involved in arsenite transport other cation transporters (Na, K, Ca , NH4, etc.) (39 ORFs) 67.04.01.02 39 YAL026C DRS2 P-type amino-phospholipids-ATPase YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YBR235W YBR235W similarity to bumetanide-sensitive Na-K-Cl cotransport protein YCR024C-A PMP1 H+-ATPase subunit, plasma membrane YDL128W VCX1 Ca2+-transport (H+/Ca2+ exchange) protein, vacuolar YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDR011W SNQ2 multidrug resistance protein YDR456W NHX1 NA+-H+ antiporter YEL017C-A PMP2 H+-ATPase subunit, plasma membrane YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL031W SPF1 P-type ATPase YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YGL006W PMC1 Ca2+-transporting P-type ATPase YGL008C PMA1 H+-transporting P-type ATPase, major isoform, plasma membrane YGL167C PMR1 Ca2+-transporting P-type ATPase YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YGR065C VHT1 plasma membrane H+-biotin symporter YGR121C MEP1 ammonia permease of high capacity and moderate affinity YHL016C DUR3 urea transport protein YHR026W PPA1 H+-ATPase 23 KD subunit, vacuolar YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YJL094C KHA1 K+/H+ exchanger YJL129C TRK1 potassium transport protein TRK1P, high-affinity YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKR050W TRK2 moderate-affinity potassium transport protein YLR138W NHA1 putative Na+/H+ antiporter YLR341W SPO77 probably ATP-powered Ca2+ pump, possible role in sporulation YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YNL142W MEP2 high affinity low capacity ammonia permease YOR153W PDR5 pleiotropic drug resistance protein YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YPL036W PMA2 H+-transporting P-type ATPase, minor isoform, plasma membrane YPL224C MMT2 mitochondrial iron transporter YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar YPR138C MEP3 low affinity high capacity ammonium permease anion transporters (Cl, SO4, PO4, etc.) (21 ORFs) 67.04.07 21 YAL067C SEO1 suppressor of sulfoxyde ethionine resistance YBR235W YBR235W similarity to bumetanide-sensitive Na-K-Cl cotransport protein YBR291C CTP1 citrate transport protein, mitochondrial (MCF) YBR294W SUL1 high-affinity sulfate transport protein YBR296C PHO89 Na+-coupled phosphate transport protein, high affinity YCR037C PHO87 member of the phosphate permease family YER053C YER053C strong similarity to mitochondrial phosphate carrier protein YGR121C MEP1 ammonia permease of high capacity and moderate affinity YHL016C DUR3 urea transport protein YJL117W PHO86 inorganic phospate transporter YJL198W PHO90 low affinity phosphate transporter YJR040W GEF1 voltage-gated chloride channel protein YJR077C MIR1 phosphate transport protein, mitochondrial (MCF) YKL120W OAC1 similarity to mitochondrial uncoupling proteins (MCF) YLR092W SUL2 sulfate transporter YLR348C DIC1 dicarboxylate carrier protein YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YNL142W MEP2 high affinity low capacity ammonia permease YNR013C PHO91 similarity to PHO87P and PHO90P YPR003C YPR003C similarity to sulphate transporter proteins YPR138C MEP3 low affinity high capacity ammonium permease C-compound and carbohydrate transporters (46 ORFs) 67.07 46 YBR241C YBR241C similarity to glucose transport proteins YBR298C MAL31 maltose permease YDL138W RGT2 suppressor of SNF3 mutant YDL194W SNF3 high-affinity glucose transporter/regulatory protein YDL198C YHM1 member of the mitochondrial carrier family (MCF) YDL199C YDL199C similarity to sugar transporter proteins YDL245C HXT15 strong similarity to HXT17P and HXT7P YDL247W YDL247W strong similarity to sugar transport proteins YDR342C HXT7 high-affinity hexose transporter YDR343C HXT6 high-affinity hexose transporter YDR345C HXT3 low-affinity hexose transporter YDR387C YDR387C similarity to ITR1P and ITR2P and E.coli araE YDR497C ITR1 myo-inositol permease, major YDR536W STL1 member of the sugar permease family YEL004W YEA4 strong similarity to K.lactis golgi uridine diphosphate-N-acetylglucosamine transporter YEL069C HXT13 high-affinity hexose transporter YFL011W HXT10 hexose transporter YFL040W YFL040W similarity to yeast glucose transport proteins YFR045W YFR045W similarity to mitochondrial citrate transport proteins YGL084C GUP1 similarity to GUP2P - putative glycerol transporter YGL104C YGL104C similarity to glucose transport proteins YGL225W GOG5 GDP-mannose transporter into the lumen of the Golgi YGR289C MAL11 general alpha-glucoside permease YHR092C HXT4 moderate- to low-affinity glucose transporter YHR094C HXT1 low-affinity hexose transporter YHR096C HXT5 member of the hexose transporter family YIL170W HXT12 strong similarity to sugar transport proteins YIL171W HXT12 strong similarity to sugar transport proteins YJL214W HXT8 hexose transport protein YJL219W HXT9 hexose transport protein YJR095W SFC1 succinate-fumarate transporter YJR158W HXT16 member of the hexose transporter family of the major facilitator superfamily [MFS] YJR160C YJR160C strong similarity to MAL31P YKL217W JEN1 carboxylic acid transporter protein YLL043W FPS1 glycerol channel protein YLR081W GAL2 galactose (and glucose) permease YLR348C DIC1 dicarboxylate carrier protein YML123C PHO84 high-affinity inorganic phosphate/H+ symporter YMR011W HXT2 high-affinity hexose transporter YNL318C HXT14 hexose transport protein YNR072W HXT17 sugar transport protein YOL103W ITR2 myo-inositol permease, minor YOL156W HXT11 low affinity glucose transport protein YOR271C YOR271C strong similarity to Rattus tricarboxylate carrier YPL189W GUP2 putative glycerol transporter involved in active glycerol uptake YPR021C YPR021C similarity to human citrate transporter protein other C-compound transporters (2 ORFs) 67.07.99 2 YGL084C GUP1 similarity to GUP2P - putative glycerol transporter YPL189W GUP2 putative glycerol transporter involved in active glycerol uptake amino-acid transporters (25 ORFs) 67.10 25 YBR068C BAP2 leucine permease, high-affinity (S1) YBR069C TAT1 amino acid permease YBR132C AGP2 amino-acid permease YCL025C AGP1 asparagine and glutamine permease YDL210W UGA4 GABA-specific high-affinity permease YDR046C BAP3 valine transporter YDR508C GNP1 high-affinity glutamine permease YEL063C CAN1 amino acid permease YFL055W AGP3 amino acid permease YGL077C HNM1 choline permease YGR055W MUP1 high affinity methionine permease YGR191W HIP1 histidine permease YHL036W MUP3 very low affinity methionine permease YKL174C YKL174C similarity to choline transport protein HNM1P YKR039W GAP1 general amino acid permease YLL061W MMP1 high affinity S-methylmethionine permease YNL268W LYP1 lysine-specific high-affinity permease YNL270C ALP1 high-affinity permease for basic amino acids YNR056C BIO5 similarity to choline transport protein HNM1P YOL020W TAT2 high affinity tryptophan transport protein YOR071C YOR071C strong similarity to Thi10p YOR130C ORT1 ornithine transport protein of mitochondria involved in arginine metabolism, member of the mitochondrial carrier family (MCF) YOR348C PUT4 proline and gamma-aminobutyrate permease YPL265W DIP5 dicarboxylic amino acid permease YPL274W SAM3 high affinity S-adenosylmethionine permease peptide transporters (1 ORF) 67.11 1 YJL212C OPT1 oligopeptide transporter specific for tetra- and pentapeptides lipid transporters (7 ORFs) 67.13 7 YCR098C GIT1 glycerophosphoinositol transporter YKL174C YKL174C similarity to choline transport protein HNM1P YKL188C PXA2 ABC transporter, peroxisomal YKL192C ACP1 mitochonrial acyl-carrier protein YNR056C BIO5 similarity to choline transport protein HNM1P YOR035C SHE4 required for mother cell-specific gene expression YPL147W PXA1 long-chain fatty acid transporter nucleotide transporters (15 ORFs) 67.16 15 YBL030C PET9 ADP/ATP carrier protein (MCF) YBR021W FUR4 uracil permease YBR085W AAC3 ADP/ATP carrier protein (MCF) YBR192W RIM2 mitochondrial carrier protein (MCF) YER056C FCY2 purine-cytosine permease YER060W FCY21 purine-cytosine permease YER060W-A FCY22 purine/cytosine permease with similarity to FCY2P YGL186C YGL186C similarity to hypothetical protein FCY21P and weak similarity to FCY2 protein YGR096W YGR096W hypothetical mitochondrial transport protein YHR002W YHR002W similarity to bovine mitochondrial carrier protein/Grave's disease carrier protein YMR056C AAC1 ADP/ATP carrier protein (MCF) YOR192C YOR192C strong similarity to Thi10p YOR222W ODC2 similarity to ADP/ATP carrier proteins YPL134C ODC1 similarity to ADP,ATP carrier proteins YPR011C YPR011C similarity to ADP/ATP carrier proteins and Graves disease carrier protein allantoin and allantoate transporters (9 ORFs) 67.19 9 YCR028C FEN2 high affinity H+/pantothenate symporter YGR260W TNA1 similarity to allantoate transport protein YIL166C YIL166C similarity to allantoate permease DAL5P YIR028W DAL4 allantoin permease YJR152W DAL5 allantoate permease YLL055W YLL055W similarity to DAL5P YLR004C YLR004C similarity to allantoate transport protein YOR071C YOR071C strong similarity to Thi10p YOR192C YOR192C strong similarity to Thi10p drug transporters (35 ORFs) 67.28 35 YBR008C FLR1 fluconazole resistance protein YBR043C YBR043C similarity to benomyl/methotrexate resistance protein YBR052C YBR052C strong similarity to S.pombe brefeldin A resistance protein obr1 YBR180W DTR1 dityrosine transporter YBR293W YBR293W similarity to multidrug resistance proteins YCL069W YCL069W strong similarity to drug resistance protein SGE1 YCL073C YCL073C strong similarity to subtelomeric encoded proteins YDR119W YDR119W similarity to B.subtilis tetracyclin resistance YEL065W SIT1 probable multidrug resistance protein YGR138C TPO2 polyamine transport protein YGR197C SNG1 involved in nitroguanidine resistance YGR224W AZR1 strong similarity to drug resistance protein SGE1, YKR105c and YCL069W YGR281W YOR1 ATP-binding cassette transporter protein YHL040C ARN1 ferrichrome-type siderophore transporter YHL047C TAF1 siderophore transporter for triacetylfusarinine C YHR032W ERC1 ethionine resistance protein YHR048W YHR048W similarity to multidrug resistance proteins YIL013C PDR11 membrane transporter YIL048W NEO1 ATPase whose overproduction confers neomycin resistance YIL120W QDR1 similarity to antibiotic resistance proteins YIL121W YIL121W similarity to antibiotic resistance proteins YKR105C YKR105C strong similarity to SGE1P and hypothetical protein YCL069w YKR106W YKR106W strong similarity to subtelomeric encoded proteins YLL028W TPO1 polyamine transport protein YML116W ATR1 aminotriazole and 4-nitroquinoline resistance protein YMR088C YMR088C similarity to multidrug resistance proteins YMR123W PKR1 resistance against Pichia farinosa killer toxin (SMK toxin) when expressed by a multi copy plasmid YMR279C YMR279C strong similarity to aminotriazole resistance protein YNL065W AQR1 similarity to resistance proteins YNR055C HOL1 member of major facilitator superfamily multidrug-resistance protein subfamily 1 YOL158C ENB1 a gene of the major facilitator superfamily encodes a transporter for enterobactin YOR273C TPO4 polyamine transporter YOR378W YOR378W strong similarity to aminotriazole resistance protein YPR156C TPO3 polyamine transporter YPR198W SGE1 drug resistance protein transport mechanism (74 ORFs) 67.50 74 YAL026C DRS2 P-type amino-phospholipids-ATPase YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YBR295W PCA1 P-type Cu2+-transporting ATPase YCR011C ADP1 ATP-dependent permease YCR024C-A PMP1 H+-ATPase subunit, plasma membrane YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDR011W SNQ2 multidrug resistance protein YDR038C ENA5 P-type ATPase involved in Na+ efflux YDR039C ENA2 P-type ATPase involved in Na+ efflux YDR040C ENA1 P-type ATPase involved in Na+ and Li+ efflux YDR091C RLI1 strong similarity to human RNase L inhibitor and M.jannaschii ABC transporter protein YDR093W YDR093W similarity to P.falciparum ATPase 2 YDR135C YCF1 glutathione S-conjugate transporter, vacuolar YDR270W CCC2 probable copper-transporting ATPase YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR375C BCS1 mitochondrial protein of the CDC48/PAS1/SEC18 (AAA) family of ATPases YDR406W PDR15 ATP-binding cassette transporter family member YEL017C-A PMP2 H+-ATPase subunit, plasma membrane YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL031W SPF1 P-type ATPase YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YER036C KRE30 strong similarity to members of the ABC transporter family YER166W YER166W similarity to ATPase P.falciparum ATPase 2 YFR009W GCN20 positive effector of GCN2P YGL006W PMC1 Ca2+-transporting P-type ATPase YGL008C PMA1 H+-transporting P-type ATPase, major isoform, plasma membrane YGL167C PMR1 Ca2+-transporting P-type ATPase YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YGR281W YOR1 ATP-binding cassette transporter protein YHL035C YHL035C similarity to multidrug resistance proteins YHR026W PPA1 H+-ATPase 23 KD subunit, vacuolar YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YIL013C PDR11 membrane transporter YIL048W NEO1 ATPase whose overproduction confers neomycin resistance YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YKL188C PXA2 ABC transporter, peroxisomal YKL209C STE6 ATP-binding cassette transporter protein YKR103W YKR103W similarity to multidrug resistance proteins YKR104W YKR104W similarity to multidrug resistance proteins YLL015W BPT1 similarity to YCF1P, YOR1P, rat organic anion transporter YLL027W ISA1 mitochondrial protein required for normal iron metabolism YLL048C YBT1 yeast bile transporter YLR188W MDL1 ATP-binding cassette transporter family member YLR295C ATP14 F1F0-ATPase complex, subunit h YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YMR162C YMR162C similarity to ATPases YMR301C ATM1 ATP-binding cassette transporter protein, mitochondrial YNL014W HEF3 translation elongation factor eEF3 homolog YNR070W YNR070W strong similarity to SNQ2P YOL075C YOL075C similarity to A.gambiae ATP-binding-cassette protein YOR011W AUS1 strong similarity to ATP-dependent permeases YOR153W PDR5 pleiotropic drug resistance protein YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR328W PDR10 member of ATP-binding cassette (ABC) superfamily YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YPL036W PMA2 H+-transporting P-type ATPase, minor isoform, plasma membrane YPL058C PDR12 multidrug resistance transporter YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL147W PXA1 long-chain fatty acid transporter YPL226W NEW1 similarity to translation elongation factor eEF3 YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPL270W MDL2 ATP-binding cassette (ABC) transporter family member YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 transport ATPases (45 ORFs) 67.50.22 45 YAL026C DRS2 P-type amino-phospholipids-ATPase YBL099W ATP1 F1F0-ATPase complex, F1 alpha subunit YBR039W ATP3 F1F0-ATPase complex, F1 gamma subunit YBR127C VMA2 H+-ATPase V1 domain 60 KD subunit, vacuolar YBR295W PCA1 P-type Cu2+-transporting ATPase YCR024C-A PMP1 H+-ATPase subunit, plasma membrane YDL004W ATP16 F1F0-ATPase complex, F1 delta subunit YDL184W-B TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDL185W TFP1 H+-ATPase V1 domain 69 KD catalytic subunit, vacuolar YDR038C ENA5 P-type ATPase involved in Na+ efflux YDR039C ENA2 P-type ATPase involved in Na+ efflux YDR040C ENA1 P-type ATPase involved in Na+ and Li+ efflux YDR093W YDR093W similarity to P.falciparum ATPase 2 YDR270W CCC2 probable copper-transporting ATPase YDR298C ATP5 F1F0-ATPase complex, OSCP subunit YDR375C BCS1 mitochondrial protein of the CDC48/PAS1/SEC18 (AAA) family of ATPases YEL017C-A PMP2 H+-ATPase subunit, plasma membrane YEL027W CUP5 H+-ATPase V0 domain 17 KD subunit, vacuolar YEL031W SPF1 P-type ATPase YEL051W VMA8 H+-ATPsynthase V1 domain 32 KD subunit, vacuolar YER166W YER166W similarity to ATPase P.falciparum ATPase 2 YGL006W PMC1 Ca2+-transporting P-type ATPase YGL008C PMA1 H+-transporting P-type ATPase, major isoform, plasma membrane YGL167C PMR1 Ca2+-transporting P-type ATPase YGR020C VMA7 H+-ATPase V1 domain 14 kDa subunit, vacuolar YHR026W PPA1 H+-ATPase 23 KD subunit, vacuolar YHR039C-A VMA10 H+-transporting ATPase V0 domain 13 KD subunit, vacuolar YIL048W NEO1 ATPase whose overproduction confers neomycin resistance YJR121W ATP2 F1F0-ATPase complex, F1 beta subunit YKL016C ATP7 F1F0-ATPase complex, FO D subunit YKL080W VMA5 H+-ATPase V1 domain 42 KD subunit, vacuolar YLR295C ATP14 F1F0-ATPase complex, subunit h YLR447C VMA6 H+-ATPase V0 domain 36 KD subunit, vacuolar YMR054W STV1 H+-ATPase V0 domain 102 KD subunit, not vacuolar YMR162C YMR162C similarity to ATPases YOR270C VPH1 H+-ATPase V0 domain 95K subunit, vacuolar YOR332W VMA4 H+-ATPase V1 domain 27 KD subunit, vacuolar YPL036W PMA2 H+-transporting P-type ATPase, minor isoform, plasma membrane YPL078C ATP4 F1F0-ATPase complex, F0 subunit B YPL234C TFP3 H+-ATPase V0 domain 17 KD subunit, vacuolar YPL271W ATP15 F1F0-ATPase complex, F1 epsilon subunit YPR036W VMA13 H+-ATPase V1 domain 54 KD subunit, vacuolar Q0080 AAP1 F1F0-ATPase complex, F0 subunit 8 Q0085 ATP6 F1F0-ATPase complex, FO A subunit Q0130 OLI1 F1F0-ATPase complex, F0 subunit 9 ABC transporters (28 ORFs) 67.50.25 28 YCR011C ADP1 ATP-dependent permease YDR011W SNQ2 multidrug resistance protein YDR091C RLI1 strong similarity to human RNase L inhibitor and M.jannaschii ABC transporter protein YDR135C YCF1 glutathione S-conjugate transporter, vacuolar YDR406W PDR15 ATP-binding cassette transporter family member YER036C KRE30 strong similarity to members of the ABC transporter family YFR009W GCN20 positive effector of GCN2P YGR281W YOR1 ATP-binding cassette transporter protein YHL035C YHL035C similarity to multidrug resistance proteins YIL013C PDR11 membrane transporter YKL188C PXA2 ABC transporter, peroxisomal YKL209C STE6 ATP-binding cassette transporter protein YKR103W YKR103W similarity to multidrug resistance proteins YKR104W YKR104W similarity to multidrug resistance proteins YLL015W BPT1 similarity to YCF1P, YOR1P, rat organic anion transporter YLL048C YBT1 yeast bile transporter YLR188W MDL1 ATP-binding cassette transporter family member YMR301C ATM1 ATP-binding cassette transporter protein, mitochondrial YNL014W HEF3 translation elongation factor eEF3 homolog YNR070W YNR070W strong similarity to SNQ2P YOL075C YOL075C similarity to A.gambiae ATP-binding-cassette protein YOR011W AUS1 strong similarity to ATP-dependent permeases YOR153W PDR5 pleiotropic drug resistance protein YOR328W PDR10 member of ATP-binding cassette (ABC) superfamily YPL058C PDR12 multidrug resistance transporter YPL147W PXA1 long-chain fatty acid transporter YPL226W NEW1 similarity to translation elongation factor eEF3 YPL270W MDL2 ATP-binding cassette (ABC) transporter family member other transport mechanisms (1 ORF) 67.50.99 1 YLL027W ISA1 mitochondrial protein required for normal iron metabolism other transport facilitators (58 ORFs) 67.99 58 YAL067C SEO1 suppressor of sulfoxyde ethionine resistance YAR035W YAT1 carnitine acetyltransferase, mitochondrial YBL011W SCT1 suppresses a choline-transport mutant YBL089W YBL089W weak similarity to A.thaliana aminoacid permease AAP3 YBR171W SEC66 ER protein-translocation complex subunit YCL038C YCL038C similarity to bacterial membrane transporter YCR017C CWH43 putative sensor/transporter protein YCR023C YCR023C weak similarity to E.coli tetracycline resistance protein TCR1 YDL149W APG9 integral membrane protein required for Cvt and autophagy transport YDL206W YDL206W weak similarity to transporter proteins YDL217C TIM22 subunit of the TIM22-complex YDR086C SSS1 ER protein-translocase complex subunit YDR322C-A TIM11 subunit E of the dimeric form of mitochondrial F1F0-ATPase YEL006W YEL006W similarity to peroxisomal membrane and mitochondrial carrier proteins YEL064C YEL064C similarity to YBL089w YER019C-A SBH2 ER protein-translocation complex subunit YER024W YAT2 carnitine O-acetyltransferase YER087C-B SBH1 involved in translocation into the ER YER119C YER119C weak similarity to E.herbicola tyrosine permease YFL054C YFL054C similarity to channel proteins YGR065C VHT1 plasma membrane H+-biotin symporter YGR082W TOM20 mitochondrial outer membrane import receptor subunit, 20 kD YIL006W YIL006W similarity to FLX1P YIL022W TIM44 mitochondrial inner membrane import receptor subunit YIL056W YIL056W similarity to YER064c YIL088C YIL088C weak similarity to A.thaliana aminoacid permease AAP4 YIL134W FLX1 FAD carrier protein (MCF), mitochondrial YJL034W KAR2 nuclear fusion protein YJL054W TIM54 translocase for the insertion of proteins into the mitochondrial inner membrane YJL143W TIM17 mitochondrial inner membrane import translocase subunit YJR001W YJR001W weak similarity to A.thaliana aminoacid permease AAP4 YJR106W ECM27 involved in cell wall biogenesis and architecture YJR124C YJR124C weak similarity to Staphylococcus multidrug resistance protein YKL146W YKL146W strong similarity to S.pombe hypothetical protein C3H1.09C YKL221W YKL221W weak similarity to human X-linked PEST-containing transporter YKR067W GPT2 strong similarity to SCT1P YKR093W PTR2 peptide transporter YLR237W THI7 thiamin transport protein YLR292C SEC72 ER protein-translocation complex subunit YLR378C SEC61 ER protein-translocation complex subunit YMR060C TOM37 mitochondrial outer membrane import receptor subunit, 37 kD YMR203W TOM40 forms the hydrophilic channel of the mitochondrial import pore for preproteins YNL003C PET8 member of the mitochondrial carrier (MCF) family YNL055C POR1 mitochondrial outer membrane porin YNL070W TOM7 mitochondrial outer membrane import receptor subunit, 7 kD YNL121C TOM70 mitochondrial outer membrane specialized import receptor YNL125C ESBP6 similarity to YKL221w and human X-linked PEST-containing transporter YNL131W TOM22 mitochondrial outer membrane import receptor complex subunit YNR017W MAS6 mitochondrial inner membrane import translocase subunit YOL119C YOL119C similarity to monocarboxylate transporter proteins YOL163W YOL163W similarity to P. putida phthalate transporter YOR045W TOM6 mitochondrial outer membrane import receptor subunit, 6 kD YOR254C SEC63 ER protein-translocation complex subunit YOR291W YOR291W similarity to cation translocating ATPases YOR306C YOR306C similarity to human X-linked PEST-containing transporter YPL094C SEC62 ER protein-translocation complex subunit YPR058W YMC1 mitochondrial carrier protein (MCF) YPR194C OPT2 similarity to S.pombe isp4 protein CLASSIFICATION NOT YET CLEAR-CUT (115 ORFs) 98 115 YAL065C YAL065C strong similarity to FLO1P and FLO9P - putative pseudogene YAR018C KIN3 ser/thr protein kinase YAR061W YAR061W strong similarity to N-terminus of FLO1P - putative pseudogene YAR062W YAR062W strong similarity to FLO1P - putative pseudogene YBL056W PTC3 ser/thr protein phosphatase PP2C YBR028C YBR028C similarity to ribosomal protein kinases YBR046C ZTA1 similarity to zeta-crystallin YBR125C PTC4 serine/threonine protein phosphatases (PP2Cs) YBR177C EHT1 alcohol acyl transferase YCL028W RNQ1 prion, epigenetic modifier of protein function YCL051W LRE1 involved in laminarinase resistance YCL068C YCL068C strong similarity to BUD5P; putative pseudogene YCR047C BUD23 weak similarity to N-methyltransferases YCR063W BUD31 strong similarity to Xenopus G10 and human edg-2 protein YCR091W KIN82 ser/thr protein kinase YDL002C NHP10 Non-histone protein YDL079C MRK1 ser/thr protein kinase YDL179W PCL9 cyclin like protein interacting with PHO85P YDL214C PRR2 strong similarity to putative protein kinase NPR1 YDL238C YDL238C similarity to E.coli hypothetical protein and to chlorohydrolases YDR036C YDR036C similarity to enoyl CoA hydratase YDR084C YDR084C similarity to hypothetical C.elegans protein YDR100W YDR100W similarity to Dictyostelium development-specific membrane protein YDR236C FMN1 Riboflavin kinase YDR276C PMP3 sensitive to natrium YDR291W YDR291W similarity to B.subtilis helicases YDR349C YPS7 GPI-anchored aspartic protease YDR466W YDR466W similarity to ser/thr protein kinase YDR490C PKH1 ser/thr protein kinases YDR501W PLM2 PLasmid Maintenance mutant shows 2mu-m plasmid instability YDR505C PSP1 high copy suppressor of ts mutations in DNA polymerase alpha YEL005C VAB2 VAC8P binding protein of 31 kDa YEL007W TOS9 similarity to S.pombe PAC2 protein YEL052W AFG1 ATPase family gene YEL055C POL5 DNA polymerase V YER059W PCL6 cyclin like protein interacting with PHO85P YER089C PTC2 protein serine/threonine phosphatase of the PP2C family YER104W RTT105 disruption causes increase in Ty1 retrotransposition YFR011C YFR011C ochre suppressor tyr-tRNA YGL028C SCW11 similarity to glucanase YGL129C RSM23 similarity to S.pombe hypothetical protein SPBC29A3.15C - putative mitochondrial function YGL179C TOS3 strong similarity to PAK1P, ELM1P and KIN82P YGL185C YGL185C weak similarity to dehydrogenases YGR123C PPT1 protein ser/thr phosphatase YGR262C BUD32 weak similarity to protein kinases and M.jannaschii O-sialoglycoprotein endopeptidase homolog YGR279C SCW4 similarity to glucanase YHR071W PCL5 cyclin like protein interacting with PHO85P YHR136C SPL2 suppressor of PLC1-delta YHR168W YHR168W similarity to GTP-binding proteins YHR187W IKI1 confers sensitivity to killer toxin YIL016W SNL1 high copy suppressor of NUP116, GLE2 and NIC96 alleles YIL050W PCL7 cyclin like protein interacting with PHO85P YIL103W YIL103W weak similarity to DPH2 protein YJL059W YHC3 may function as a chaperone, similarity to human Batten disease-related protein CLN3 YJR110W YJR110W similarity to human myotubularin YJR134C SGM1 similarity to paramyosin, myosin YKL116C PRR1 similarity to rat SNF1, Celegans unc-51, DUN1P and other protein serine kinases YKL126W YPK1 ser/thr-specific protein kinase YKL168C KKQ8 ser/thr protein kinase YKL171W YKL171W weak similarity to ser/thr protein kinase YKR010C TOF2 topoisomerase I interacting factor 2 YLL002W REM50 drug resistance YLL019C KNS1 ser/thr protein kinase YLL022C HIF1 HAT1 Interacting Factor 1 YLL034C YLL034C similarity to mammalian valosin YLL046C RNP1 ribonucleoprotein YLR063W YLR063W hypothetical protein YLR080W YLR080W strong similarity to EMP47P YLR118C YLR118C similarity to several esterases YLR193C YLR193C similarity to G.gallus px19 and MSF1P YLR276C DBP9 similarity to YDL031w, MAK5P and RNA helicases YLR281C YLR281C similarity to polypeptide chain release factors YLR384C IKI3 confers sensitivity to killer toxin YLR409C YLR409C strong similarity to S. pombe beta-transducin YLR419W YLR419W similarity to helicases YLR459W CDC91 cell division control protein YMR027W HRT2 high level expression reduced Ty3 transposition YMR077C VPS20 similarity to SNF7 protein YMR099C YMR099C similarity to P.ciliare possible apospory-associated protein YMR110C YMR110C similarity to aldehyde dehydrogenase YMR226C YMR226C similarity to ketoreductases YMR305C SCW10 similarity to B.japonicum putative beta-(-6)glucan transferase YNL002C RLP7 strong similarity to mammalian ribosomal L7 proteins YNL023C FAP1 similarity to D.melanogaster shuttle craft protein YNL161W CBK1 strong similarity to U.maydis Ukc1p protein kinase YNL275W YNL275W similarity to human band 3 anion transport protein YNR015W SMM1 similarity to E.histolytica nitrogen fixation regulatory protein-3 homolog YNR047W YNR047W similarity to ser/thr protein kinases YNR067C YNR067C similarity to beta-glucan-elicitor receptor - Glycine max YOL109W ZEO1 weak similarity to G.hirsutum embryonic abundant protein D-7 YOL132W YOL132W similarity to glycophospholipid-anchored surface glycoprotein GAS1P YOL164W YOL164W similarity to Pseudomonas alkyl sulfatase YOR008C-A KIM1 reduced growth in diepoxybutane and/or mitomycin C YOR032C HMS1 weak similarity to DNA-binding proteins YOR046C DBP5 RNA helicase YOR165W YOR165W similarity to E.histolytica surface lectin YOR227W YOR227W similarity to microtubule-interacting protein MHP1P YOR233W KIN4 ser/thr protein kinase YOR246C YOR246C weak similarity to reductases YOR256C YOR256C strong similarity to secretory protein SSP134P YOR355W GDS1 NAM9-1 suppressor YOR374W ALD4 aldehyde dehydrogenase, mitochondrial YOR383C FIT3 weak similarity to L.mexicana secreted acid phosphatase 2 YPL024W NCE4 negative regulator of CTS1 expression YPL109C YPL109C similarity to aminoglycoside acetyltransferase regulator from P. stuartii YPL116W HOS3 similarity to HOS1P, HOS2P, HOS3P, RPD3P and human histone deacetylase HD1 YPL236C YPL236C similarity to PRK1P, and serine/threonine protein kinase homolog from A. thaliana YPL252C YAH1 similarity to adrenodoxin and ferrodoxin YPR042C PUF2 similarity to JSN1P YPR073C LTP1 protein-tyrosine-phosphatase YPR106W ISR1 protein kinase YPR112C MRD1 similarity to RNA-binding proteins YPR140W YPR140W similarity to human BTHS gene involved in Barth syndrome YPR164W KIM3 drug resistance YPR188C MLC2 similarity to calmodulin and calmodulin-related proteins UNCLASSIFIED PROTEINS (2399 ORFs) 99 2399 YAL008W FUN14 hypothetical protein YAL014C (FUN34) hypothetical protein YAL016C-A YAL016C-A questionable ORF YAL017W FUN31 similarity to ser/thr protein kinases YAL018C YAL018C weak similarity to hypothetical proteins YOL047c and YOL048c YAL019W-A YAL019W-A questionable ORF YAL026C-A YAL026C-A questionable ORF YAL027W YAL027W hypothetical protein YAL028W YAL028W similarity to hypothetical protein YOR324c YAL031C FUN21 hypothetical protein YAL031W-A YAL031W-A questionable ORF YAL034C FUN19 similarity to hypothetical protein YOR338w YAL034C-B YAL034C-B questionable ORF YAL036C FUN11 strong similarity to GTP-binding proteins YAL037C-A YAL037C-A hypothetical protein - identified by SAGE YAL037C-B YAL037C-B similarity to Z. rouxii hypothetical protein YAL037W YAL037W strong similarity to GTP-binding proteins YAL042C-A KRE23 questionable ORF YAL044W-A YAL044W-A similarity to S. pombe uvi31 YAL045C YAL045C hypothetical protein YAL046C YAL046C weak similarity to hypothetical protein S. pombe YAL047W-A YAL047W-A similarity to S. bayanus hypothetical protein YAL049C YAL049C weak similarity to Legionella small basic protein sbpA YAL053W YAL053W strong similarity to hypothetical proteins YOR365c,YGL139w,YPL221w YAL056C-A KRE20 questionable ORF YAL056W GPE2 similarity to hypothetical protein YOR371c YAL059C-A YAL059C-A questionable ORF YAL064C-A YAL064C-A strong similarity to FLO1P, FLO5P - putative pseudogene YAL064W YAL064W hypothetical protein YAL064W-B YAL064W-B questionable ORF YAL066W YAL066W weak similarity to membrane protein yybF - Bacillus subtilis YAL068C YAL068C strong similarity to subtelomeric encoded proteins YAR014C BUD14 similarity to hypothetical protein S.pombe YAR019W-A YAR019W-A questionable ORF YAR023C YAR023C strong similarity to FUN55P, FUN59P, YGL051w, YCR007c, YGL053w, YAR031w and YAR028w YAR027W FUN55 strong similarity to YAR028w, YCR007c, YGL053w, YAR031w, FUN59P and YGL051w YAR028W YAR028W strong similarity to FUN55P, YGL053w, YCR007c, YAR031w, FUN59P and YGL051w YAR029W FUN57 strong similarity to YAR031w, YGL053w, FUN55P, FUN59P and YGL051w YAR030C YAR030C hypothetical protein YAR031W PRM9 strong similarity to YGL053w, FUN59P, YGL051w, FUN55P, YAR028w and YCR007c YAR033W FUN59 strong similarity to YGL051w, YGL053w, YAR031w, FUN55P, YAR028w and YCR007c YAR047C YAR047C hypothetical protein YAR053W YAR053W hypothetical protein YAR060C YAR060C identical to hypothetical protein YHR212c YAR064W YAR064W hypothetical protein YAR066W YAR066W similarity to Sta1p, identical to YHR214w hypothetical protein YAR068W YAR068W strong similarity to hypothetical protein YHR214w-a YAR069C YAR069C hypothetical protein YAR070C YAR070C hypothetical protein YBL004W YBL004W weak similarity to Papaya ringspot virus polyprotein YBL006C YBL006C hypothetical protein YBL010C YBL010C hypothetical protein YBL012C YBL012C questionable ORF YBL029C-A YBL029C-A similarity to S. servazzii YBL029W YBL029W hypothetical protein YBL031W SHE1 hypothetical protein YBL032W YBL032W weak similarity to hnRNP complex protein homolog YBR233w YBL036C YBL036C strong similarity to C.elegans hypothetical protein YBL044W YBL044W hypothetical protein YBL046W YBL046W weak similarity to hypothetical protein YOR054c YBL047C EDE1 similarity to mouse eps15R protein YBL048W YBL048W hypothetical protein YBL049W YBL049W strong similarity to hypothetical protein - human YBL051C PIN4 similarity to S.pombe Z66568_C protein YBL053W YBL053W questionable ORF YBL055C YBL055C similarity to hypothetical S.pombe protein YBL057C YBL057C strong similarity to hypothetical S.pombe protein YBL059C-A YBL059C-A weak similarity to hypothetical protein SPBC21D10.07 S. pombe YBL059W YBL059W weak similarity to hypothetical protein YER093c-a YBL060W YBL060W weak similarity to probable guanine nucleotide exchange factor, S.pombe YBL062W YBL062W questionable ORF YBL065W YBL065W questionable ORF YBL070C YBL070C questionable ORF YBL071C YBL071C hypothetical protein YBL071W-A YBL071W-A similarity to K. marxianus YBL073W YBL073W questionable ORF YBL077W YBL077W questionable ORF YBL081W YBL081W hypothetical protein YBL083C YBL083C questionable ORF YBL091C-A YBL091C-A weak similarity to SCS2 YBL094C YBL094C questionable ORF YBL095W YBL095W similarity to C.albicans hypothetical protein YBL096C YBL096C questionable ORF YBL100C YBL100C questionable ORF YBL104C YBL104C weak similarity to S.pombe hypothetical protein SPAC12G12.01c YBL107C YBL107C hypothetical protein YBL107W-A YBL107W-A questionable ORF - identified by SAGE YBL108C-A YBL108C-A similarity to S. bayanus YBL108W YBL108W strong similarity to subtelomeric encoded proteins YBL109W YBL109W similarity to subtelomeric encoded proteins YBL111C YBL111C strong similarity to subtelomeric encoded proteins YBL112C YBL112C strong similarity to subtelomeric encoded proteins YBL113C YBL113C similarity to Y' ORFs YBR004C YBR004C similarity to S.pombe hypothetical protein SPAC18B11.05 YBR005W YBR005W strong similarity to hypothetical protein YDR003w YBR007C YBR007C hypothetical protein YBR012C YBR012C hypothetical protein YBR013C YBR013C hypothetical protein YBR016W YBR016W strong similarity to hypothetical proteins YDL012c and YDR210w YBR022W YBR022W weak similarity to hypothetical protein Mycobacterium tuberculosis YBR025C YBR025C strong similarity to Ylf1p YBR027C YBR027C hypothetical protein YBR032W YBR032W hypothetical protein YBR047W YBR047W hypothetical protein YBR051W YBR051W questionable ORF YBR053C YBR053C similarity to rat regucalcin YBR056W-A YBR056W-A hypothetical protein - identified by SAGE YBR062C YBR062C similarity to rat neurodegeneration associated protein 1 YBR063C YBR063C hypothetical protein YBR064W YBR064W questionable ORF YBR066C NRG2 weak similarity to A.niger carbon catabolite repressor protein YBR071W YBR071W hypothetical protein YBR074W YBR074W weak similarity to aminopeptidase Y YBR075W YBR075W weak similarity to hypothetical protein S. pombe YBR077C YBR077C hypothetical protein YBR085C-A YBR085C-A hypothetical protein - identified by SAGE YBR086C IST2 weak similarity to calcium and sodium channel proteins YBR089W YBR089W questionable ORF YBR090C YBR090C questionable ORF YBR094W YBR094W weak similarity to pig tubulin-tyrosine ligase YBR095C YBR095C weak similarity to hypothetical protein S. pombe YBR096W YBR096W weak similarity to CG4660; D. melanogaster YBR099C YBR099C weak similarity to T.brucei mitochondrion hypothetical protein 6 YBR100W YBR100W questionable ORF YBR101C YBR101C weak similarity to S.pombe hypothetical protein SPBC3B9.01 YBR103C-A YBR103C-A similarity to S. bayanus YBR108W YBR108W weak similarity to R.norvegicus atrophin-1 related protein YBR109W-A YBR109W-A questionable ORF - upstream ORF of ALG1 YBR113W YBR113W questionable ORF YBR116C YBR116C questionable ORF YBR124W YBR124W questionable ORF YBR126W-A YBR126W-A hypothetical protein - identified by SAGE YBR134W YBR134W questionable ORF YBR137W YBR137W similarity to hypothetical protein Streptomyces coelicolor YBR141C YBR141C similarity to hypothetical protein S. pombe YBR144C YBR144C hypothetical protein YBR147W YBR147W strong similarity to hypothetical protein YOL092w YBR151W APD1 weak similarity to potato sucrose cleavage protein YBR155W CNS1 weak similarity to stress-induced STI1P YBR157C ICS2 hypothetical protein YBR162C TOS1 similarity to hypothetical protein YJL171c YBR163W DEM1 weak similarity to PTA1P (pre-tRNA processing protein) YBR174C YBR174C questionable ORF YBR175W SWD3 similarity to S.pombe beta-transducin YBR178W YBR178W questionable ORF YBR184W YBR184W hypothetical protein YBR187W YBR187W similarity to mouse putative transmembrane protein FT27 YBR190W YBR190W questionable ORF YBR191W-A YBR191W-A similarity to S. bayanus YBR194W YBR194W hypothetical protein YBR197C YBR197C weak similarity to hypothetical protein YPL077c YBR203W YBR203W hypothetical protein YBR206W YBR206W questionable ORF YBR209W YBR209W hypothetical protein YBR216C YBR216C strong similarity to hypothetical protein YGL060w YBR220C YBR220C similarity to human acetyl-coenzyme A transporter YBR223C YBR223C hypothetical protein YBR224W YBR224W questionable ORF YBR225W YBR225W hypothetical protein YBR226C YBR226C questionable ORF YBR228W SLX1 similarity to hypothetical A.thaliana protein YBR230C YBR230C hypothetical protein YBR231C AOR1 similarity to human BCNT protein NP_006315.1 YBR232C YBR232C questionable ORF YBR233W-A YBR233W-A similarity to Z. rouxii YBR242W YBR242W strong similarity to hypothetical protein YGL101w YBR246W YBR246W similarity to TREMBL:SPCC18_15 hypothetical protein, S. pombe YBR250W YBR250W weak similarity to hypothetical protein S. pombe YBR255C-A YBR255C-A similarity to S. bayanus YBR255W YBR255W hypothetical protein YBR258C SHG1 hypothetical protein YBR259W YBR259W weak similarity to 'BH1924', sugar transport system; Bacillus halodurans YBR261C YBR261C similarity to hypothetical S. pombe protein YBR262C YBR262C questionable ORF YBR266C YBR266C questionable ORF YBR267W YBR267W similarity to hypothetical protein YLR387c YBR269C YBR269C weak similarity to 'cpa', phospholipase C, Clostridium perfringens YBR270C YBR270C strong similarity to hypothetical protein YJL058c YBR271W YBR271W weak similarity to S.pombe uvi22 protein and hypothetical protein YNL024c YBR273C YBR273C similarity to hypothetical protein YJL048c YBR277C YBR277C questionable ORF YBR280C YBR280C similarity to hypothetical protein S. pombe YBR281C YBR281C similarity to hypothetical protein YFR044c YBR285W YBR285W weak similarity to RecQ5, D. melanogaster YBR287W YBR287W similarity to hypothetical S. pombe protein YBR292C YBR292C hypothetical protein YBR300C YBR300C strong similarity to hypothetical protein YGR293c YBR302C COS2 strong similarity to subtelomeric encoded proteins YCL001W-A YCL001W-A similarity to DOM34P YCL001W-B YCL001W-B similarity to S. servazzii YCL002C YCL002C strong similarity to Saccharomyces pastorianus hypothetical protein LgYCL002c YCL005W YCL005W strong similarity to Saccharomyces pastorianus hypothetical protein LgYCL005w YCL010C YCL010C strong similarity to Saccharomyces pastorianus hypothetical protein LgYCL010c YCL021W-A YCL021W-A hypothetical protein YCL023C YCL023C questionable ORF YCL026C-B YCL026C-B strong similarity to FRM2 YCL036W YCL036W similarity to hypothetical protein YDR514c YCL039W YCL039W similarity to TUP1P general repressor of RNA polymerase II transcription YCL041C YCL041C questionable ORF YCL042W YCL042W questionable ORF YCL044C YCL044C similarity to hypothetical protein K. lactis YCL045C YCL045C weak similarity to human ORF YCL046W YCL046W questionable ORF YCL047C YCL047C similarity to hypothetical protein SPAC694.03 S. pombe YCL049C YCL049C similarity to 'unknown protein'; S. pastorianus YCL056C YCL056C hypothetical protein YCL057C-A YCL057C-A strong similarity to hypothetical protein S.pombe YCL058C FYV5 hypothetical protein YCL061C MRC1 similarity to URK1 YCL063W YCL063W weak similarity to yeast translation regulator GCD6P YCL065W YCL065W strong similarity to probable membrane protein YCR041w YCR001W YCR001W weak similarity to chloride channel proteins YCR006C YCR006C hypothetical protein YCR007C YCR007C strong similarity to subtelomeric encoded proteins YCR013C YCR013C similarity to M.leprae B1496_F1_41 protein YCR015C YCR015C hypothetical protein YCR016W YCR016W hypothetical protein YCR018C-A YCR018C-A questionable ORF - identified by SAGE YCR020W-B HTL1 similarity to S. bayanus YCR022C YCR022C hypothetical protein YCR025C YCR025C hypothetical protein YCR026C YCR026C similarity to human autotaxin precursor YCR030C YCR030C weak similarity to S.pombe hypothetical protein SPBC4C3.06 YCR033W YCR033W similarity to nuclear receptor co-repressor N-Cor YCR038W-A YCR038W-A similarity to S. bayanus YCR041W YCR041W questionable ORF YCR043C YCR043C hypothetical protein YCR049C YCR049C questionable ORF YCR050C YCR050C questionable ORF YCR051W YCR051W weak similarity to ankyrins YCR054C CTR86 weak similarity to THR4P YCR059C YIH1 weak similarity to hypothetical protein YDL177c YCR061W YCR061W similarity to YTP1 YCR064C YCR064C questionable ORF YCR068W CVT17 similarity to starvation induced pSI-7 protein of C. fluvum YCR076C YCR076C weak similarity to latent transforming growth factor beta binding protein 3' H. sapiens YCR079W YCR079W weak similarity to A.thaliana protein phosphatase 2C YCR082W YCR082W weak similarity to RBK1P YCR085W YCR085W hypothetical protein YCR087W YCR087W questionable ORF YCR090C YCR090C similarity to S. pombe SPBC2D10.03c YCR095C YCR095C similarity to Saccharomyces kluyveri strain NRRL Y-12651 YCR097W-A YCR097W-A similarity to S. bayanus YCR102C YCR102C similarity to C.carbonum toxD gene YCR102W-A YCR102W-A similarity to other hypothetical yeast proteins YDL001W YDL001W similarity to hypothetical protein YFR048w, YDR282c and S.pombe hypothetical protein SPAC12G12.14 YDL009C YDL009C questionable ORF YDL011C YDL011C questionable ORF YDL012C YDL012C strong similarity to hypothetical protein YBR016w and YDR210w YDL016C YDL016C questionable ORF YDL023C YDL023C questionable ORF YDL026W YDL026W questionable ORF YDL027C YDL027C weak similarity to hypothetical protein Methanococcus jannaschii YDL032W YDL032W questionable ORF YDL033C YDL033C similarity to H.influenzae hypothetical protein HI0174 YDL034W YDL034W questionable ORF YDL038C YDL038C similarity to mucin proteins YDL039C PRM7 hypothetical protein YDL041W KRE26 questionable ORF YDL046W YDL046W strong similarity to phosphatidylglycerol/phosphatidylinositol transfer protein YDL050C YDL050C questionable ORF YDL054C YDL054C similarity to hypothetical protein C. albicans YDL057W YDL057W weak similarity to hypothetical protein A. thaliana YDL060W TSR1 similarity to C.elegans hypothetical protein YDL062W YDL062W questionable ORF YDL063C YDL063C weak similarity to human estrogen-responsive finger protein YDL068W YDL068W questionable ORF YDL071C YDL071C questionable ORF YDL072C YDL072C weak similarity to hypothetical protein YMR040w YDL073W YDL073W weak similarity to Cyprinus carpio calcium channel protein YDL074C BRE1 weak similarity to spindle pole body protein NUF1 YDL076C YDL076C weak similarity to hypothetical protein S. pombe YDL085C-A YDL085C-A questionable ORF - identified by SAGE YDL086W YDL086W similarity to hypothetical Synechocystis protein YDL089W YDL089W weak similarity to hypothetical protein S. pombe YDL091C YDL091C weak similarity to mouse FAF1 protein YDL094C YDL094C questionable ORF YDL096C YDL096C questionable ORF YDL099W YDL099W weak similarity to myosin heavy chain proteins YDL105W QRI2 weak similarity to proteins of unknown function YDL110C YDL110C hypothetical protein YDL113C YDL113C similarity to hypothetical protein YDR425w YDL114W-A YDL114W-A similarity to S. bayanus hypothetical protein YDL115C IWR1 weak similarity to hypothetical protein D. melanogaster YDL117W CYK3 similarity to hypothetical S. pombe protein, protein possibly involved in cytokinesis YDL118W YDL118W questionable ORF YDL121C YDL121C hypothetical protein YDL123W SNA4 similarity to hypothetical protein SNA3/YJL151c YDL129W YDL129W hypothetical protein YDL133W YDL133W hypothetical protein YDL139C SCM3 hypothetical protein YDL144C YDL144C weak similarity to probable oxidoreductase - Streptomyces coelicolor YDL146W YDL146W weak similarity to ORC3P YDL151C FYV3 questionable ORF YDL152W YDL152W questionable ORF YDL156W YDL156W weak similarity to Pas7p YDL157C YDL157C hypothetical protein YDL158C YDL158C questionable ORF YDL159W-A YDL159W-A similarity to S. bayanus hypothetical protein YDL162C YDL162C hypothetical protein YDL163W YDL163W questionable ORF YDL166C YDL166C weak similarity to Pyrococcus horikoshii hypothetical protein PHBJ019 YDL167C NRP1 similarity to human TAF2N Zinc finger TBP-associated factor N, component of the TFIID complex YDL169C UGX2 hypothetical protein YDL172C YDL172C questionable ORF YDL173W YDL173W hypothetical protein YDL175C YDL175C weak similarity to cellular nucleic acid binding proteins YDL176W YDL176W hypothetical protein YDL177C YDL177C similarity to hypothetical protein YCR059c YDL180W YDL180W hypothetical protein YDL183C YDL183C weak similarity to S.pombe hypothetical protein SPAC23H3 YDL185C-A YDL185C-A similarity to S. bayanus hypothetical protein YDL186W YDL186W hypothetical protein YDL187C YDL187C questionable ORF YDL189W YDL189W weak similarity to 'KIAA1002'; H. sapiens YDL193W YDL193W similarity to N.crassa hypothetical 32 kDa protein YDL196W YDL196W hypothetical protein YDL201W YDL201W strong similarity to probable methyltransferase related protein Neurospora crassa YDL204W YDL204W similarity to hypothetical protein YDR233c YDL209C YDL209C similarity to hypothetical S. pombe protein YDL211C YDL211C similarity to hypothetical protein YNL176c YDL213C FYV14 weak similarity to potato small nuclear ribonucleoprotein U2B and human splicing factor homolog YDL216C RRI1 similarity to Jun activation domain binding protein homologue of A. thaliana YDL218W YDL218W weak similarity to hypothetical protein YNR061c YDL219W YDL219W strong similarity to S.equisimilis hypothetical protein YDL221W YDL221W questionable ORF YDL222C YDL222C strong similarity to hypothetical protein YNL194c and similarity to YML052w YDL223C YDL223C weak similarity to mucin YDL228C YDL228C similarity to A.klebsiana glutamate dehydrogenase YDL231C BRE4 similarity to hypothetical protein SPAC26F1.08c S. pombe YDL233W YDL233W hypothetical protein YDL237W YDL237W weak similarity to hypothetical protein, Streptomyces coelicolor YDL239C ADY3 hypothetical protein YDL240C-A YDL240C-A similarity to S. bayanus hypothetical protein YDL241W YDL241W hypothetical protein YDL242W YDL242W strong similarity to hypothetical protein YPR079w YDL247W-A YDL247W-A similarity to S. bayanus hypothetical protein YDL248W COS7 strong similarity to subtelomeric encoded proteins YDR003W YDR003W strong similarity to hypothetical protein YBR005w YDR008C YDR008C questionable ORF YDR010C YDR010C hypothetical protein YDR013W YDR013W similarity to human hypothetical KIAA0186 protein YDR014W YDR014W weak similarity to chicken neurofilament triplet M protein YDR015C YDR015C hypothetical protein YDR016C DAD1 hypothetical protein YDR018C YDR018C strong similarity to hypothetical protein YBR042c YDR024W FYV1 hypothetical protein YDR029W YDR029W hypothetical protein YDR031W YDR031W weak similarity to squalene synthase; Artemisia annua YDR032C PST2 strong similarity to S.pombe obr1 brefeldin A resistance protein YDR034C-A YDR034C-A questionable ORF - identified by SAGE YDR034W-B YDR034W-B questionable ORF - identified by SAGE YDR042C YDR042C hypothetical protein YDR048C YDR048C questionable ORF YDR049W YDR049W similarity to C.elegans K06H7.3 protein YDR051C YDR051C similarity to hypothetical A. thaliana protein BAC F7G19 YDR053W YDR053W questionable ORF YDR056C YDR056C hypothetical protein YDR063W YDR063W weak similarity to glia maturation factor beta YDR065W YDR065W hypothetical protein YDR066C YDR066C similarity to hypothetical protein YER139c YDR067C YDR067C similarity to YNL099c YDR068W DOS2 weak similarity to mouse transcription factor UBF YDR070C YDR070C hypothetical protein YDR071C YDR071C similarity to O.aries arylalkylamine N-acetyltransferase YDR078C YDR078C hypothetical protein YDR079C-A YDR079C-A similarity to S. bayanus hypothetical protein YDR089W YDR089W weak similarity to Streptococcus transposase YDR090C YDR090C weak similarity to YRO2 protein YDR094W YDR094W questionable ORF YDR095C YDR095C hypothetical protein YDR101C YDR101C weak similarity to proliferation-associated protein YDR102C YDR102C hypothetical protein YDR105C YDR105C similarity to mouse hypothetical protein YDR109C YDR109C similarity to MPA43P YDR112W YDR112W questionable ORF YDR114C YDR114C questionable ORF YDR124W YDR124W hypothetical protein YDR126W PSL10 similarity to hypothetical protein YLR246w and YOL003c YDR128W YDR128W weak similarity to SEC27P, YMR131c and human retinoblastoma-binding protein YDR131C YDR131C similarity to hypothetical protein YJL149w YDR132C YDR132C strong similarity to hypothetical protein YLR108c YDR133C YDR133C questionable ORF YDR136C YDR136C questionable ORF YDR141C DOP1 strong similarity to Emericella nidulans developmental regulatory gene, dopey (dopA) YDR149C YDR149C questionable ORF YDR152W YDR152W weak similarity to C.elegans hypothetical protein CET26E3 YDR153C YDR153C weak similarity to lqf protein D. melanogaster YDR154C YDR154C questionable ORF YDR157W YDR157W questionable ORF YDR161W TCI1 weak similarity to S. pombe protein of unknown function SPBC16D10.01c YDR163W YDR163W weak similarity to S.pombe hypothetical protein YDR165W YDR165W weak similarity to hypothetical C.elegans protein YDR179C YDR179C weak similarity to hypothetical protein D. melanogaster YDR179W-A YDR179W-A hypothetical protein YDR186C YDR186C hypothetical protein YDR187C YDR187C questionable ORF YDR193W YDR193W questionable ORF YDR196C YDR196C similarity to C.elegans hypothetical protein T05G5.5 YDR198C YDR198C similarity to hypothetical protein S. pombe YDR199W YDR199W questionable ORF YDR200C YDR200C similarity to hypothetical protein YLR238w YDR202C RAV2 hypothetical protein YDR203W YDR203W questionable ORF YDR205W MSC2 similarity to A.eutrophus cation efflux system membrane protein czcD, rat zinc transport protein ZnT-1 and COT1P YDR209C YDR209C questionable ORF YDR210W YDR210W strong similarity to hypothetical protein YBR016w YDR214W YDR214W similarity to hypothetical protein YNL281w YDR215C YDR215C hypothetical protein YDR219C YDR219C hypothetical protein YDR220C YDR220C questionable ORF YDR221W YDR221W weak similarity to the beta subunit of an ER luminal alpha-glucosidase from mouse YDR222W YDR222W strong similarity to hypothetical protein YLR225c YDR223W YDR223W similarity to IFH1P YDR229W YDR229W similarity to hypothetical protein N. crassa YDR230W YDR230W questionable ORF YDR239C YDR239C hypothetical protein YDR241W BUD26 questionable ORF YDR247W YDR247W strong similarity to SKS1P YDR249C YDR249C weak similarity to cytochrome b YDR250C YDR250C hypothetical protein YDR255C YDR255C weak similarity to hypothetical S.pombe hypothetical protein SPBC29A3 YDR262W YDR262W hypothetical protein YDR266C YDR266C similarity to hypothetical C.elegans protein YDR267C YDR267C weak similarity to human TAFII100 and other WD-40 repeat containing proteins YDR269C YDR269C questionable ORF YDR271C YDR271C questionable ORF YDR273W YDR273W weak similarity to YOR042w YDR274C YDR274C hypothetical protein YDR275W YDR275W weak similarity to YOR042w YDR278C YDR278C hypothetical protein YDR279W YDR279W hypothetical protein YDR281C PHM6 hypothetical protein, has a role in phosphate metabolism YDR282C YDR282C similarity to hypothetical protein YDL001w, YFR048w and S.pombe hypothetical protein SPAC12G12.14 YDR286C YDR286C weak similarity hypothetical protein - A. thaliana YDR288W YDR288W hypothetical protein YDR290W YDR290W questionable ORF YDR295C PLO2 weak similarity to USO1P, YPR179c and fruit fly tropomyosin YDR306C YDR306C weak similarity to S.pombe hypothetical protein SPAC6F6 YDR314C YDR314C weak similarity to hypothetical S.pombe protein YDR316W YDR316W similarity to hypothetical ubiquitin system protein S. pombe YDR317W YDR317W hypothetical protein YDR319C YDR319C weak similarity to ARE2P YDR320C-A YDR320C-A similarity to S. bayanus hypothetical protein YDR324C YDR324C weak similarity to beta transducin from S. pombe and other WD-40 repeat containing proteins YDR326C YDR326C strong similarity to YHR080c, similarity to YFL042c and YLR072w YDR327W YDR327W questionable ORF YDR332W YDR332W similarity to E.coli hypothetical protein and weak similarity to RNA helicase MSS116 / YDR194c YDR333C YDR333C similarity to hypothetical S. pombe protein YDR336W YDR336W weak similarity to B.subtilis hypothetical protein X YDR338C YDR338C similarity to ERC1P YDR339C YDR339C weak similarity to hypothetical protein YOR004w YDR340W YDR340W questionable ORF YDR344C YDR344C hypothetical protein YDR346C YDR346C similarity to hypothetical S.pombe protein YDR348C YDR348C similarity to hypothetical protein YHR097c YDR350C TCM10 hypothetical protein YDR352W YDR352W weak similarity to hypothetical proteins YOL092w, YBR147w and YMR010w YDR355C YDR355C questionable ORF YDR357C YDR357C hypothetical protein YDR359C VID21 weak similarity to human trichohyalin YDR360W YDR360W questionable ORF YDR361C BCP1 similarity to hypothetical protein S. pombe YDR365C YDR365C weak similarity to Streptococcus M protein YDR366C YDR366C similarity to YOL106w and YER181c YDR367W YDR367W similarity to hypothetical protein SPAC26H5.13c S. pombe YDR370C YDR370C hypothetical protein YDR374C YDR374C similarity to hypothetical A. thaliana protein BAC F21M12 YDR379C-A YDR379C-A similarity to P. angusta hypothetical protein YDR381C-A YDR381C-A similarity to K. marxianus hypothetical protein YDR383C YDR383C weak similarity to S.pombe paramyosin YDR391C YDR391C strong similarity to hypothetical protein YOR013w YDR393W SHE9 weak similarity to rabbit trichohyalin YDR396W YDR396W hypothetical protein YDR398W YDR398W similarity to human KIAA0007 gene YDR401W YDR401W questionable ORF YDR411C YDR411C weak similarity to DER1P YDR412W YDR412W similarity to hypothetical protein SPAC29A4.09 - S. pombe YDR413C YDR413C weak similarity to NADH dehydrogenase YDR417C YDR417C questionable ORF YDR425W YDR425W similarity to hypothetical protein YDL113c YDR426C YDR426C questionable ORF YDR428C YDR428C weak similarity to predicted esterase of proteobacterium YDR430C YDR430C similarity to C.perfringens hypothetical hypA protein YDR431W YDR431W questionable ORF YDR433W KRE22 questionable ORF YDR434W GPI17 similarity to S.pombe hypothetical protein YDR437W YDR437W weak similarity to DSCR5b H. sapiens YDR438W YDR438W strong similarity to hypothetical protein YML018c YDR442W YDR442W questionable ORF YDR445C YDR445C questionable ORF YDR449C YDR449C similarity to hypothetical protein S. pombe YDR455C YDR455C questionable ORF YDR458C YDR458C similarity to hypothetical protein YML034w and YML033w YDR459C YDR459C weak similarity to YNL326c YDR467C YDR467C questionable ORF YDR469W SDC1 weak similarity to D. melanogaster hypothetical protein YDR470C UGO1 similarity to chromosome segregation protein CSE1P YDR474C YDR474C similarity to C-terminal region of YOR019w YDR475C YDR475C weak similarity to N-terminal region of YOR019w YDR476C YDR476C hypothetical protein YDR479C YDR479C weak similarity to YHR150w YDR482C YDR482C hypothetical protein YDR485C YDR485C similarity to trichohyalin YDR486C VPS60 weak similarity to SNF7P YDR489W YDR489W weak similarity to hypothetical protein S. pombe YDR491C YDR491C questionable ORF YDR492W YDR492W strong similarity to hypothetical protein YOL002c YDR493W YDR493W similarity to hypothetical protein Neurospora crassa YDR494W RCT1 weak similarity to hypothetical protein D. melanogaster YDR496C PUF6 similarity to hypothetical human and C.elegans proteins YDR504C YDR504C similarity to hypothetical T.brucei protein YDR509W YDR509W questionable ORF YDR511W ACN9 weak similarity to C. elegans protein F25H9.7 and to the human complement 3 precursor YDR512C YDR512C questionable ORF YDR514C YDR514C strong similarity to hypothetical protein YCL036w YDR520C YDR520C weak similarity to transcription factors of the zinc finger class YDR521W YDR521W questionable ORF YDR524C AGE1 similarity to ADP-ribosylation factor (ARF) GTPase activating protein (GAP) with effector functions YDR524C-B YDR524C-B hypothetical protein - identified by SAGE YDR524W-A YDR524W-A hypothetical protein - identified by SAGE YDR525W YDR525W hypothetical protein YDR525W-A SNA2 similarity to PMP3/SNA1 YDR526C YDR526C questionable ORF YDR527W YDR527W weak similarity to Plasmodium yoelii rhoptry protein YDR528W HLR1 similarity to LRE1P YDR531W YDR531W similarity to hypothetical A. thaliana and C. elegans proteins YDR532C KRE28 weak similarity Plasmodium repeat organellar protein YDR533C YDR533C strong similarity to hypothetical proteins YPL280w, YOR391c and YMR322c YDR534C FIT1 similarity to YOR383c,Sta1p and pig mucin YDR535C YDR535C hypothetical protein YDR537C YDR537C questionable ORF YDR539W YDR539W similarity to E.coli hypothetical 55.3 kDa protein in rfah-rfe intergenic region YDR540C YDR540C similarity to E. coli unknown gene YDR542W YDR542W strong similarity to subtelomeric encoded proteins YDR543C YDR543C strong similarity to subtelomeric encoded proteins YDR544C YDR544C strong similarity to subtelomeric encoded proteins YEL001C YEL001C hypothetical protein YEL008W YEL008W hypothetical protein YEL009C-A YEL009C-A questionable ORF YEL010W YEL010W hypothetical protein YEL014C YEL014C hypothetical protein YEL015W YEL015W weak similarity to SPA2P YEL016C YEL016C similarity to human nucleotide pyrophosphatase YEL017W YEL017W hypothetical protein YEL018C-A YEL018C-A questionable ORF YEL018W YEL018W weak similarity to RAD50P YEL023C YEL023C similarity to hypothetical protein PA2063 - Pseudomonas aeruginosa YEL025C SRI1 hypothetical protein YEL028W YEL028W hypothetical protein YEL029C BUD16 similarity to hypothetical protein YNR027w YEL030C-A YEL030C-A similarity to Debaryomyces hansenii hypothetical protein YEL033W YEL033W weak similarity to Sauroleishmania mitochondrial hypothetical ORF-5 protein YEL034C-A YEL034C-A similarity to Pichia angusta hypothetical protein YEL035C UTR5 weak similarity to Neisseria gonorrhoeae PilG protein YEL041W YEL041W strong similarity to UTR1P YEL043W YEL043W weak similarity to MAD1P YEL044W IES6 similarity to SPAC222.04c hypothetical protein S. pombe YEL045C YEL045C weak similarity to cytochrome c oxidase III of T.brucei kinetoplast YEL048C YEL048C weak similarity to trp-asp repeat protein - S. pombe YEL053W-A YEL053W-A similarity to K. lactis hypothetical protein YEL057C YEL057C hypothetical protein YEL059W YEL059W hypothetical protein YEL067C YEL067C weak similarity to YKL083w YEL068C YEL068C hypothetical protein YEL072W YEL072W hypothetical protein YEL073C YEL073C similarity to YJR108w YEL074W YEL074W similarity to subtelomeric encoded proteins YEL075C YEL075C strong similarity to subtelomeric encoded proteins YEL075W-A YEL075W-A questionable ORF YEL076C-B YEL076C-B strong similarity to subtelomeric encoded proteins YEL077C YEL077C strong similarity to subtelomeric encoded proteins YER004W YER004W similarity to hypothetical E.coli and C.elegans proteins YER006C-A YER006C-A questionable ORF YER007C-A YER007C-A strong similarity to C.elegans AF045640 and S.pombe SPBC31F10 YER010C YER010C similarity to L.pneumophila dlpA protein YER014C-A BUD25 questionable ORF YER030W YER030W similarity to mouse nucleolin YER033C ZRG8 weak similarity to NMD2P, KEX1P and hamster nucleolin YER034W YER034W hypothetical protein YER035W EDC2 weak similarity to EDC1 YER037W PHM8 strong similarity to hypothetical protein YGL224c YER038C KRE29 hypothetical protein YER038W-A YER038W-A questionable ORF YER039C-A YER039C-A similarity to S. bayanus YER041W YEN1 weak similarity to DNA repair protein RAD2P and Dsh1p YER046W SPO73 hypothetical protein YER046W-A YER046W-A questionable ORF YER048W-A YER048W-A similarity to D. melanogaster protein YER049W YER049W strong similarity to hypothetical S.pombe protein YER049W YER051W YER051W similarity to C.elegans hypothetical protein YER063W THO1 weak similarity to human heterogeneous ribonuclear particle protein U YER064C YER064C similarity to hypothetical protein YIL056w YER066C-A YER066C-A hypothetical protein YER067C-A YER067C-A questionable ORF YER067W YER067W strong similarity to hypothetical protein YIL057c YER068C-A YER068C-A questionable ORF YER071C YER071C hypothetical protein YER074W-A YER074W-A similarity to S. bayanus YER076W-A YER076W-A questionable ORF YER077C YER077C hypothetical protein YER079C-A YER079C-A similarity to Saccharomyces servazzii hypothetical protein YER079W YER079W hypothetical protein YER080W YER080W hypothetical protein YER082C KRE31 similarity to M.sexta steroid regulated MNG10 protein YER083C YER083C hypothetical protein YER084W YER084W questionable ORF YER084W-A YER084W-A questionable ORF YER085C YER085C weak similarity to myosins YER087C-A YER087C-A questionable ORF YER088C-A YER088C-A questionable ORF YER091C-A YER091C-A hypothetical protein - identified by SAGE YER092W IES5 weak similarity to tryptophan synthase beta subunit - Aquifex aeolicus YER093C YER093C weak similarity to S.epidermidis PepB protein YER093C-A YER093C-A similarity to hypothetical protein YBL059w YER097W YER097W weak similarity to ribosomal S3 proteins YER106W MAM1 weak similarity to At2g20470 A. thaliana YER107W-A YER107W-A questionable ORF YER113C YER113C similarity to EMP70P YER119C-A YER119C-A questionable ORF YER121W YER121W hypothetical protein YER124C YER124C weak similarity to Dictyostelium WD40 repeat protein 2 YER126C KRE32 weak similarity to E.coli colicin N YER128W YER128W hypothetical protein YER133W-A YER133W-A questionable ORF YER134C YER134C weak similarity to S.pombe SPBC13G1 and C.elegans F26F2.d hypothetical proteins YER135C YER135C hypothetical protein YER137C YER137C weak similarity to Mycoplasma hominis P120 protein YER137W-A YER137W-A questionable ORF YER138W-A YER138W-A questionable ORF - identified by SAGE YER139C YER139C similarity to hypothetical protein YDR066c YER140W YER140W similarity to PIR:T39406 hypothetical protein S. pombe YER145C-A YER145C-A questionable ORF YER147C SCC4 protein required for sister chromatid cohesion YER147C-A YER147C-A similarity to Saccharomyces exiguus and S. servazzii hypothetical protein YER148W-A YER148W-A questionable ORF YER152C YER152C weak similarity to E.coli hypothetical protein f470 YER152W-A YER152W-A questionable ORF YER156C YER156C similarity to hypothetical C. elegans protein C27H6.5 YER158C YER158C weak similarity to AFR1P YER163C YER163C weak similarity to E.coli cation transport protein YER165C-A YER165C-A questionable ORF YER167W BCK2 suppressor of mutations in protein kinase C pathway components YER172C-A YER172C-A hypothetical protein YER175C TMT1 similarity to hypothetical protein YHR209w YER181C YER181C questionable ORF YER182W YER182W similarity to hypothetical protein SPAC3A12.08 - S. pombe YER186C YER186C weak similarity to hypothetical protein YMR316w YER188C-A YER188C-A strong similarity to subtelomeric encoded proteins YER188W YER188W weak similarity to viral RNA replicase YER189W YER189W strong similarity to subtelomeric encoded proteins YFL006W YFL006W similarity to hypothetical protein TRCDSEMBL:AB024034_15 A. thaliana YFL007W BLM3 weak similarity to Mms19p YFL010C YFL010C questionable ORF YFL012W YFL012W hypothetical protein YFL012W-A YFL012W-A questionable ORF YFL013C IES1 weak similarity to Dictyostelium protein kinase YFL013W-A YFL013W-A questionable ORF YFL015C YFL015C weak similarity to YDR504c YFL015W-A YFL015W-A questionable ORF YFL019C YFL019C hypothetical protein YFL021C-A YFL021C-A hypothetical protein YFL023W FYV11 similarity to repeat structures in a Plasmodium falciparum protein (MESA) that binds human erythrocyte protein 4.1. YFL024C EPL1 weak similarity to YMR164c and GAL11P YFL027C GYP8 weak similarity to P.falciparum Pfmdr2 protein YFL032W YFL032W questionable ORF YFL034W YFL034W similarity to hypothetical S. pombe protein and to C.elegans F35D11 protein YFL042C YFL042C similarity to hypothetical protein YLR072w YFL044C YFL044C weak similarity to human dystrophin YFL046W YFL046W weak similarity to middle part of C.elegans myosin heavy chain A YFL049W YFL049W weak similarity to NPL6P YFL062W COS4 strong similarity to subtelomeric encoded proteins YFL063W YFL063W strong similarity to subtelomeric encoded proteins YFL064C YFL064C strong similarity to subtelomeric encoded proteins YFL065C YFL065C strong similarity to subtelomeric encoded proteins YFL066C YFL066C strong similarity to subtelomeric encoded proteins YFL067W YFL067W similarity to mouse period clock protein YFL068W YFL068W weak similarity to hypothetical E.coli protein YFR001W LOC1 weak similarity to rabbit triadin SPP41P YFR003C YFR003C strong similarity to hypothetical protein SPAC6B12.13 - S.pombe YFR007W YFR007W weak similarity to YER176w YFR008W YFR008W weak similarity to human centromere protein E YFR012W YFR012W similarity to hypothetical protein YOL019w YFR012W-A YFR012W-A similarity to S. bayanus YFR016C YFR016C similarity to mammalian neurofilament proteins and to Dictyostelium protein kinase YFR017C YFR017C hypothetical protein YFR020W YFR020W hypothetical protein YFR021W AUT10 similarity to hypothetical protein YPL100w YFR026C YFR026C hypothetical protein YFR032C YFR032C weak similarity to S.pombe polyadenylate-binding protein, YPR112c and SBP1P YFR035C YFR035C hypothetical protein YFR036W-A YFR036W-A questionable ORF YFR039C YFR039C similarity to hypothetical protein YGL228w YFR042W YFR042W hypothetical protein YFR043C YFR043C hypothetical protein YFR044C YFR044C similarity to hypothetical protein YBR281c YFR046C YFR046C hypothetical protein YFR048W YFR048W similarity to hypothetical S.pombe protein SPAC12G12.14 and to YDL001w and YDR282c YFR052C-A YFR052C-A questionable ORF YFR054C YFR054C hypothetical protein YFR056C YFR056C questionable ORF YFR057W YFR057W weak similarity to CHA4P YGL004C YGL004C weak similarity to TUP1P YGL005C COD5 weak similarity to Xenopus kinesin-related protein Eg5 YGL006W-A YGL006W-A hypothetical protein - identified by SAGE YGL007W YGL007W questionable ORF YGL010W YGL010W similarity to hypothetical S. pombe protein YGL015C YGL015C hypothetical protein YGL020C YGL020C weak similarity to TRCDSEMBL:SPBC543_10 putative coiled-coil protein S. pombe YGL023C PIB2 phosphatidylinositol 3-phosphate binding YGL024W YGL024W questionable ORF YGL034C YGL034C questionable ORF YGL036W MTC2 similarity to EDE1P YGL037C PNC1 similarity to PIR:B70386 pyrazinamidase/nicotinamidase - Aquifex aeolicus YGL041C YGL041C weak similarity to YJL109c YGL042C YGL042C questionable ORF YGL045W YGL045W similarity to TRCDSEMBL:AF173842_1 Rim8p C. albicans YGL046W YGL046W similarity to TRCDSEMBL:AF173842_1 Rim8p C. albicans YGL047W YGL047W similarity to hypothetical S. pombe protein YGL050W YGL050W similarity to hypothetical protein SPAC25B8.15c S. pombe YGL051W YGL051W strong similarity to YAR033w protein YGL052W YGL052W questionable ORF YGL053W PRM8 strong similarity to hypothetical proteins YAR031w, YGL051w, YAR028w, YAR033w and YCR007c YGL057C YGL057C hypothetical protein YGL059W YGL059W similarity to rat branched-chain alpha-ketoacid dehydrogenase kinase YGL060W YGL060W strong similarity to hypothetical protein YBR216c YGL064C YGL064C similarity to YLR276c and YKR024c YGL066W YGL066W similarity to human ATAXIN 7 YGL069C YGL069C questionable ORF YGL072C YGL072C questionable ORF YGL074C YGL074C questionable ORF YGL079W YGL079W hypothetical protein YGL080W YGL080W strong similarity to C.elegans R07E5.13 protein YGL081W YGL081W hypothetical protein YGL082W YGL082W strong similarity to hypothetical protein YPL191c YGL083W SCY1 weak similarity to bovine rhodopsin kinase and to YGR052w YGL085W YGL085W weak similarity to Staphylococcus aureus nuclease (SNase) YGL088W YGL088W questionable ORF YGL098W YGL098W hypothetical protein YGL099W KRE35 similarity to putative human GTP-binding protein MMR1 YGL101W YGL101W strong similarity to hypothetical protein YBR242w YGL102C YGL102C questionable ORF YGL107C YGL107C strong similarity to hypothetical protein YBR238c YGL108C YGL108C weak similarity to hypotetical S.pombe protein YGL109W YGL109W questionable ORF YGL110C YGL110C similarity to hypothetical protein SPCC1906.02c S. pombe YGL111W YGL111W weak similarity to hypothetical protein S. pombe YGL113W SLD3 weak similarity to YOR165w YGL114W YGL114W weak similarity to H.influenzae permease YGL117W YGL117W hypothetical protein YGL118C YGL118C questionable ORF YGL121C YGL121C hypothetical protein YGL124C MON1 similarity to S.pombe hypothetical protein YGL132W YGL132W questionable ORF YGL136C YGL136C weak similarity to E.coli ftsJ protein YGL138C YGL138C hypothetical protein YGL139W YGL139W strong similarity to hypothetical protein YPL221w YGL140C YGL140C weak similarity to Lactobacillus putative histidine protein kinase SppK YGL146C YGL146C hypothetical protein YGL149W YGL149W questionable ORF YGL152C YGL152C questionable ORF YGL159W YGL159W hypothetical protein YGL161C YGL161C weak similarity to TRCDSEMBL:HS167A19_1 dJ167A19.1 human YGL164C YGL164C similarity to S.pombe hypothetical protein SPAC31A2.10 YGL165C YGL165C questionable ORF YGL168W YGL168W questionable ORF YGL170C SPO74 hypothetical protein YGL174W BUD13 weak similarity to C.elegans hypothetical protein R08D7.1 YGL176C YGL176C weak similarity to Oryctolagus calcium channel BIII YGL177W YGL177W questionable ORF YGL182C YGL182C questionable ORF YGL183C MND1 weak similarity to hypothetical coiled-coil protein S. pombe YGL188C YGL188C hypothetical protein YGL193C YGL193C questionable ORF YGL196W YGL196W similarity to hypothetical protein SPAC1039.06 S. pombe YGL198W YGL198W weak similarity to YIP1P YGL199C YGL199C questionable ORF YGL204C YGL204C questionable ORF YGL211W YGL211W similarity to M.jannaschii hypothetical proteins MJ1157 and MJ1478 YGL214W YGL214W questionable ORF YGL217C YGL217C questionable ORF YGL218W YGL218W questionable ORF YGL219C MMM2 similarity to hypothetical protein SPBC19C2.11c - S. pombe YGL220W YGL220W weak similarity to V.alginolyticus bolA protein YGL222C EDC1 weak similarity to EDC2 YGL223C TFI1 weak similarity to Clostridium regulatory protein YGL224C YGL224C strong similarity to hypothetical protein YER037w YGL228W SHE10 similarity to hypothetical protein YFR039c YGL230C YGL230C hypothetical protein YGL231C YGL231C similarity to hypothetical protein SPCC1281.03c - S. pombe YGL232W YGL232W weak similarity to P.falciparum dihydropteroate synthase YGL235W YGL235W questionable ORF YGL239C YGL239C questionable ORF YGL242C YGL242C weak similarity to Drosophila ANK protein YGL246C RAI1 weak similarity to C.elegans dom-3 protein YGL247W YGL247W similarity to hypothetical protein YHR036w YGL250W YGL250W weak similarity to hypothetical protein S. pombe YGL258W YGL258W strong similarity to hypothetical protein YOR387c YGL258W-A YGL258W-A similarity to S. bayanus YGL259W YPS5 similarity to hypothetical aspartyl proteinase YIR039C YGL260W YGL260W strong similarity to subtelomeric encoded proteins YGL261C YGL261C strong similarity to members of the SRP1/TIP1 family YGL262W YGL262W similarity to hypothetical protein YER187w YGL263W COS12 similarity to subtelomeric encoded proteins YGR001C YGR001C similarity to C.elegans hypothetical M142.5 protein YGR002C YGR002C similarity to hypothetical S. pombe protein YGR003W YGR003W similarity to D.melanogaster lin19 protein YGR004W YGR004W strong similarity to hypothetical protein YLR324w YGR010W YGR010W strong similarity to hypothetical protein YLR328w YGR011W YGR011W questionable ORF YGR015C YGR015C similarity to hypothetical protein YGR031w YGR016W YGR016W weak similarity to M.jannaschii hypothetical protein MJ1317 YGR017W YGR017W weak similarity to TRCDSEMBL:AC006418_11 A. thaliana YGR018C YGR018C questionable ORF YGR021W YGR021W similarity to M.leprae yfcA protein YGR022C YGR022C questionable ORF YGR024C YGR024C weak similarity to Methanobacterium thermoautotrophicum hypothetical protein MTH972 YGR025W YGR025W questionable ORF YGR026W YGR026W hypothetical protein YGR031W YGR031W similarity to hypothetical protein YGR015c and weak similarity H.influenzae dihydrolipoamide acetyltransferase YGR033C YGR033C weak similarity to TRCDSEMBLNEW:AP002861_10 Oryza sativa YGR035C YGR035C hypothetical protein YGR038W ORM1 strong similarity to hypothetical protein YLR350w YGR039W YGR039W questionable ORF YGR042W YGR042W weak similarity to TRCDSEMBL:CH20111_1 Troponin-I; Clupea harengus YGR045C YGR045C questionable ORF YGR046W YGR046W similarity to proline transport helper PTH1 C. albicans YGR050C YGR050C questionable ORF YGR051C YGR051C questionable ORF YGR052W YGR052W similarity to ser/thr protein kinases YGR053C YGR053C weak similarity to PIR:T49786 hypothetical protein B9J10.230 Neurospora crassa YGR054W YGR054W similarity to C.elegans E04D5.1 protein YGR058W YGR058W similarity to mouse calcium-binding protein YGR064W YGR064W questionable ORF YGR066C YGR066C similarity to hypothetical protein YBR105c YGR068C YGR068C weak similarity to ROD1P YGR069W YGR069W questionable ORF YGR071C YGR071C similarity to hypothetical protein YLR373c YGR073C YGR073C questionable ORF YGR079W YGR079W hypothetical protein YGR081C YGR081C weak similarity to mammalian myosin heavy chain YGR086C YGR086C strong similarity to hypothetical protein YPL004c YGR089W YGR089W weak similarity to rat tropomyosin YGR090W YGR090W similarity to PIR:T40678 hypothetical protein SPBC776.08c S. pombe YGR093W YGR093W similarity to hypothetical S.pombe protein YGR101W YGR101W weak similarity to B.subtilis YqgP YGR102C YGR102C hypothetical protein YGR103W RRP13 similarity to zebrafish essential for embryonic development gene pescadillo YGR106C YGR106C hypothetical protein YGR107W YGR107W questionable ORF YGR110W YGR110W weak similarity to YLR099c and YDR125c YGR111W YGR111W weak similarity to mosquito carboxylesterase YGR114C YGR114C questionable ORF YGR115C YGR115C questionable ORF YGR117C YGR117C hypothetical protein YGR122C-A YGR122C-A questionable ORF - identified by SAGE YGR122W YGR122W hypothetical protein YGR125W YGR125W similarity to S.pombe hypothetical protein SPAC24H6.11c YGR126W YGR126W weak similarity to hypothetical protein YPR156c YGR127W YGR127W weak similarity to mouse T10 protein YGR128C YGR128C hypothetical protein YGR130C YGR130C weak similarity to myosin heavy chain proteins YGR134W CAF130 hypothetical protein YGR137W YGR137W questionable ORF YGR139W YGR139W questionable ORF YGR141W YGR141W strong similarity to hypothetical protein YPR157w YGR145W YGR145W similarity to C.elegans hypothetical protein YGR146C YGR146C hypothetical protein YGR149W YGR149W similarity to PIR:T40675 hypothetical protein SPBC776.05 S. pombe YGR150C YGR150C similarity to PIR:T39838 hypothetical protein SPBC19G7.07c S. pombe YGR151C YGR151C questionable ORF YGR153W TOS10 hypothetical protein YGR154C YGR154C strong similarity to hypothetical proteins YKR076w and YMR251w YGR156W PTI1 weak similarity to PIR:A40220 cleavage stimulation factor 64K chain - human YGR160W FYV13 weak similarity to C. elegans Y113G7B.12 protein of unknown function YGR161C YGR161C hypothetical protein YGR161W-A YGR161W-A similarity to S. bayanus YGR163W GTR2 similarity to human ragA protein and GTR1P YGR164W YGR164W questionable ORF YGR165W YGR165W similarity to PIR:T39444 hypothetical protein SPBC14C8.16c S. pombe YGR168C YGR168C hypothetical protein YGR173W YGR173W strong similarity to human GTP-binding protein YGR176W YGR176W questionable ORF YGR182C YGR182C questionable ORF YGR187C HGH1 weak similarity to human HMG1P and HMG2P YGR190C YGR190C questionable ORF YGR196C FYV8 weak similarity to Tetrahymena acidic repetitive protein ARP1 YGR198W YGR198W weak similarity to PIR:T38996 hypothetical protein SPAC637.04 S. pombe YGR203W YGR203W weak similarity to X.laevis protein-tyrosin-phosphatase cdc homolog 2 and to hypothetical protein YPR200c YGR205W YGR205W similarity to S.pombe hypothetical protein D89234 YGR206W YGR206W similarity to Xenopus transcription factor Oct-1.17 YGR210C YGR210C similarity to M.jannaschii GTP-binding protein and to M.capricolum hypothetical protein SGC3 YGR211W ZPR1 similarity to M.musculus zinc finger protein ZPR1 YGR212W YGR212W weak similarity to S.pombe hypothetical protein SPAC18B11.03c YGR215W RSM27 strong similarity to hypothetical S. pombe protein YGR219W YGR219W questionable ORF YGR221C TOS2 similarity to hypothetical protein YHR149c YGR223C YGR223C weak similarity to hypothetical protein YFR021w YGR226C YGR226C hypothetical protein YGR228W YGR228W questionable ORF YGR235C YGR235C hypothetical protein YGR236C SPG1 hypothetical protein YGR237C YGR237C weak similarity to YOR019w YGR242W YGR242W questionable ORF YGR243W YGR243W strong similarity to hypothetical protein YHR162w YGR247W YGR247W hypothetical protein YGR250C YGR250C weak similarity to human cleavage stimulation factor 64K chain YGR251W YGR251W hypothetical protein YGR259C YGR259C questionable ORF YGR263C YGR263C weak similarity to E.coli lipase like enzyme YGR265W YGR265W questionable ORF YGR266W YGR266W hypothetical protein YGR268C YGR268C weak similarity to S.pombe hypothetical protein SPAC17A5 YGR269W YGR269W questionable ORF YGR271C-A YGR271C-A similarity to S. bayanus YGR272C YGR272C similarity to hypothetical S.pombe protein SPAC12G12.02 YGR273C YGR273C similarity to hypothetical protein YMR295c YGR277C YGR277C similarity to hypothetical S.pombe protein YGR278W YGR278W similarity to C.elegans LET-858 YGR280C YGR280C weak similarity to CBF5P YGR283C YGR283C similarity to hypothetical protein YMR310c YGR284C ERV29 similarity to mouse Surf-4 protein YGR290W YGR290W hypothetical protein YGR291C YGR291C hypothetical protein YGR293C YGR293C strong similarity to hypothetical protein YBR300c YGR294W YGR294W strong similarity to members of the SRP1P/TIP1P family YGR295C COS6 strong similarity to subtelomeric encoded proteins YGR296W YRF1-3 strong similarity to YPL283c; YNL339c and other Y' encoded proteins YHL002C-A YHL002C-A questionable ORF YHL005C YHL005C hypothetical protein YHL006C SHU1 hypothetical protein YHL006W-A YHL006W-A questionable ORF YHL010C YHL010C similarity to C.elegans hypothetical protein, homolog to human breast cancer-associated protein BRAP2 YHL013C YHL013C similarity to C.elegans hypothetical protein F21D5.2 YHL014C YLF2 similarity to E.coli GTP-binding protein YHL017W YHL017W strong similarity to PTM1P YHL019W-A YHL019W-A questionable ORF YHL021C YHL021C weak similarity to Pseudomonas gamma-butyrobetaine hydroxylase YHL023C YHL023C weak similarity to TRCDSEMBL:SPBC543_4 hypothetical protein S.pombe YHL026C YHL026C similarity to PIR:T41446 conserved hypothetical protein SPCC594.02c S. pombe YHL029C YHL029C hypothetical protein YHL030W-A YHL030W-A questionable ORF YHL034W-A YHL034W-A similarity to S. bayanus hypothetical protein YHL037C YHL037C hypothetical protein YHL039W YHL039W weak similarity to YPL208w YHL041W YHL041W weak similarity to Drosophila hypothetical protein 6 YHL042W YHL042W similarity to subtelomeric encoded proteins YHL044W YHL044W similarity to subtelomeric encoded proteins YHL045W YHL045W strong similarity to subtelomeric encoded proteins YHL046W-A YHL046W-A questionable ORF YHL048W COS8 strong similarity to subtelomeric encoded proteins YHL049C YHL049C strong similarity to subtelomeric encoded proteins YHL050C YHL050C strong similarity to subtelomeric encoded proteins YHR009C YHR009C similarity to S.pombe hypothetical protein YHR017W YSC83 strong similarity to S.douglasii YSD83 YHR022C YHR022C weak similarity to ras-related protein YHR028W-A YHR028W-A questionable ORF YHR029C YHR029C similarity to S.lincolnensis lmbX protein YHR034C YHR034C weak similarity to TRCDSEMBL:AK000650_1 unnamed ORF; Homo sapiens YHR035W YHR035W weak similarity to human SEC23 protein YHR036W YHR036W similarity to hypothetical protein YGL247w YHR040W YHR040W weak similarity to HIT1P YHR045W YHR045W hypothetical protein YHR049C-A YHR049C-A questionable ORF YHR049W YHR049W similarity to S.pombe dihydrofolate reductase and YOR280c YHR052W CIC1 adaptor protein specifically linking the 26S proteasome to its substrate, the SCF component CDC4 YHR054C YHR054C weak similarity to YOR262w YHR056W-A YHR056W-A questionable ORF YHR059W FYV4 weak similarity to Ustilago hordei B east mating protein 2 YHR063W-A YHR063W-A questionable ORF YHR067W YHR067W weak similarity to PIR:T39292 hypothetical protein SPBC1105.15c S. pombe YHR069C-A YHR069C-A similarity to S. bayanus hypothetical protein YHR070C-A YHR070C-A questionable ORF YHR071C-A YHR071C-A questionable ORF YHR074W QNS1 weak similarity to B.subtilis spore outgrowth factor B YHR078W YHR078W hypothetical protein YHR080C YHR080C similarity to hypothetical protein YDR326c, YFL042c and YLR072w YHR081W YHR081W weak similarity to human C1D protein YHR083W YHR083W hypothetical protein YHR085W YHR085W weak similarity to fruit fly brahma transcriptional activator YHR087W YHR087W weak similarity to PIR:T50363 hypothetical protein SPBC21C3.19 S.pombe YHR088W RPF1 similarity to hypothetical protein YNL075w YHR093W AHT1 hypothetical protein YHR095W YHR095W hypothetical protein YHR097C YHR097C strong similarity to hypothetical protein YDR348c YHR098C SFB3 similarity to human hypothetical protein YHR100C YHR100C strong similarity to PIR:T48794 hypothetical protein Neurospora crassa YHR105W YHR105W weak similarity to MVP1P YHR114W BZZ1 similarity to S.pombe hypothetical protein and human protein-tyrosine kinase fer YHR115C YHR115C strong similarity to hypothetical protein YNL116w YHR116W YHR116W weak similarity to TRCDSEMBLNEW:AE003592_6 CG4186 D. melanogaster YHR121W YHR121W weak similarity to C.elegans hypothetical protein YHR122W YHR122W similarity to hypothetical C. elegans protein F45G2.a YHR125W YHR125W questionable ORF YHR126C YHR126C hypothetical protein YHR130C YHR130C weak similarity to T.brucei H+-transporting ATP synthase YHR131C YHR131C similarity to hypothetical protein YNL144c YHR131W-A YHR131W-A questionable ORF YHR132W-A YHR132W-A strong similarity to hypothetical S. cerevisiae gene product of YNL157w YHR133C YHR133C similarity to hypothetical protein YNL156c YHR134W WSS1 similarity to S. pombe SPCC1442.07c putative Zn-protease YHR138C YHR138C hypothetical protein YHR139C-A YHR139C-A hypothetical protein YHR140W YHR140W hypothetical protein YHR143W YHR143W weak similarity to a-agglutinin core protein AGA1 YHR145C YHR145C questionable ORF YHR149C YHR149C similarity to hypothetical protein YGR221c YHR150W YHR150W weak similarity to YDR479c YHR151C YHR151C hypothetical protein YHR159W YHR159W hypothetical protein YHR162W YHR162W strong similarity to hypothetical protein YGR243w YHR165W-A YHR165W-A questionable ORF YHR167W THP2 subunit of the THO complex, which appears to functionally connect transcription elongation with mitotic recombination YHR173C YHR173C hypothetical protein YHR177W YHR177W weak similarity to Spombe PAC2 protein YHR180W YHR180W hypothetical protein YHR181W YHR181W similarity to mouse TEG-261 protein YHR182C-A YHR182C-A similarity to S. servazzii hypothetical protein YHR182W YHR182W weak similarity to PIR:S58162 probable Rho GTPase protein S. pombe YHR186C YHR186C similarity to C.elegans hypothetical protein C10C5.6 YHR191C CTF8 weak similarity to hypothetical protein B24H17.20 Neurospora crassa YHR192W YHR192W hypothetical protein YHR193C-A YHR193C-A questionable ORF YHR194W YHR194W similarity to hypothetical protein YOR147w YHR196W YHR196W weak similarity to YDR398w YHR197W YHR197W weak similarity to PIR:T22172 hypothetical protein F44E5.2 C. elegans YHR198C YHR198C strong similarity to hypothetical protein YHR199c YHR199C YHR199C strong similarity to hypothetical protein YHR198c YHR202W YHR202W similarity to S.pombe hypothetical protein SPAC17G6 YHR207C YHR207C weak similarity to YPL165c YHR209W YHR209W similarity to hypothetical protein YER175c YHR212C YHR212C identical to hypothetical protein YAR060c YHR213W YHR213W strong similarity to FLO5P, FLO1P, FLO9P - putative pseudogene YHR214W YHR214W similarity to Sta1, identical to YAR066w, strong imilarity to YIL169c, YOL155c YHR214W-A YHR214W-A strong similarity to hypothetical protein YAR068w YHR217C YHR217C strong similarity to subtelomeric encoded YDR544c YHR218W YHR218W strong similarity to subtelomeric encoded proteins YHR218W-A YHR218W-A strong similarity to subtelomeric encoded proteins YHR219W YHR219W strong similarity to other subtelomeric encoded proteins YIL001W YIL001W similarity to S.pombe hypothetical protein, weak similarity to human ankyrin YIL003W DRE3 strong similarity to NBP35P and human nucleotide-binding protein YIL007C YIL007C similarity to C.elegans hypothetical protein YIL012W YIL012W hypothetical protein YIL014C-A YIL014C-A strong similarity to hypothetical protein YIL102c YIL017C VID28 similarity to S. pombe SPAC26H5.04 protein of unknown function YIL019W YIL019W weak similarity to S.pombe hypothetical protein SPAC3F10 YIL020C-A YIL020C-A questionable ORF YIL023C YIL023C similarity to mouse MHC H-2K/t-w5-linked ORF precursor YIL024C YIL024C hypothetical protein YIL025C YIL025C weak similarity to E.gracilis RNA polymerase subunit YIL027C KRE27 hypothetical protein YIL028W YIL028W hypothetical protein YIL029C YIL029C strong similarity to hypothetical protein YPR071w YIL029W-A YIL029W-A questionable ORF YIL030W-A YIL030W-A questionable ORF YIL032C YIL032C hypothetical protein YIL037C PRM2 weak similarity to C. elegans F26G1.6 protease YIL039W YIL039W weak similarity to hypothetical protein SPAC23A1.02c S. pombe YIL040W YIL040W weak similarity to T.brucei NADH dehydrogenase YIL041W YIL041W similarity to S.pombe hypothetical protein YIL044C AGE2 weak similarity to zinc finger protein GCS1P YIL047C-A YIL047C-A questionable ORF YIL054W FYV2 weak similarity to fruit fly NADH dehydrogenase YIL055C YIL055C hypothetical protein YIL057C YIL057C strong similarity to YER067w YIL058W YIL058W hypothetical protein YIL059C YIL059C hypothetical protein YIL060W YIL060W questionable ORF YIL064W YIL064W weak similarity to fowlpox virus major core protein YIL066W-A YIL066W-A questionable ORF YIL067C YIL067C hypothetical protein YIL068W-A YIL068W-A questionable ORF YIL071C PCI8 hypothetical protein YIL071W-A YIL071W-A questionable ORF YIL077C YIL077C hypothetical protein YIL079C YIL079C strong similarity to hypothetical protein YDL175c YIL083C YIL083C similarity to conserved hypothetical protein SPCC4B3.18 S. pombe YIL086C YIL086C hypothetical protein YIL087C YIL087C weak similarity to hypothetical protein SPAC17A3.02 S. pombe YIL089W YIL089W similarity to hypothetical protein YLR036c YIL090W YIL090W similarity to hypothetical S. pombe protein YIL091C YIL091C weak similarity to SPT5P YIL092W YIL092W hypothetical protein YIL093C RSM25 weak similarity to S.pombe hypothetical protein SPBC16A3 YIL096C YIL096C weak similarity to hypothetical protein SPCC1919.13c S. pombe YIL097W FYV10 weak similarity to erythroblast macrophage protein EMP Mus musculus YIL100C-A YIL100C-A questionable ORF YIL100W YIL100W similarity to mouse Gcap1 protein and fruit fly Bkm-like sex-determining region hypothetical protein CS314 YIL102C YIL102C strong similarity to YIL014c-a YIL104C YIL104C similarity to hypothetical S. pombe protein YIL108W YIL108W similarity to hypothetical S. pombe protein YIL110W YIL110W weak similarity to hypothetical C.elegans protein YIL112W YIL112W similarity to ankyrin and coiled-coil proteins YIL115W-A YIL115W-A questionable ORF YIL117C PRM5 similarity to hypothetical protein YNL058c YIL122W YIL122W weak similarity to transcription adaptor protein p300 - human YIL127C YIL127C weak similarity to SMY2P YIL132C CSM2 hypothetical protein YIL135C YIL135C similarity to Ymk1p YIL141W YIL141W questionable ORF YIL142C-A YIL142C-A similarity to S. bayanus hypothetical protein YIL151C YIL151C similarity to mitochondrial aldehyde dehydrogenase Ald1p YIL152W YIL152W hypothetical protein YIL156W-A YIL156W-A questionable ORF YIL157C YIL157C weak similarity to PIR:T39578 hypothetical protein SPBC16E9.03c S. pombe YIL158W YIL158W similarity to hypothetical protein YKR100c YIL161W YIL161W hypothetical protein YIL163C YIL163C questionable ORF YIL164C NIT1 strong similarity to nitrilases, putative pseudogene YIL165C YIL165C similarity to nitrilases YIL169C YIL169C similarity to glucan 1,4-alpha-glucosidase and YAR066w YIL171W-A YIL171W-A questionable ORF YIL174W YIL174W strong similarity to subtelomeric encoded proteins YIL175W YIL175W strong similarity to subtelomeric encoded proteins YIL176C YIL176C strong similarity to members of the SRP1P/TIP1P family YIL177C YIL177C strong similarity to subtelomeric encoded proteins YIR003W YIR003W weak similarity to mammalian neurofilament triplet H proteins YIR007W YIR007W hypothetical protein YIR010W YIR010W hypothetical protein YIR013C GAT4 strong similarity to GAT3, similarity to GAT2 YIR014W YIR014W hypothetical protein YIR016W YIR016W weak similarity to YOL036w YIR017W-A YIR017W-A questionable ORF YIR020C YIR020C hypothetical protein YIR020C-B YIR020C-B hypothetical protein YIR020W-A YIR020W-A questionable ORF - identified by SAGE YIR023C-A YIR023C-A questionable ORF YIR025W MND2 hypothetical protein YIR030W-A YIR030W-A similarity to K. thermotolerans hypothetical protein YIR036W-A YIR036W-A questionable ORF YIR040C YIR040C strong similarity to subtelomeric encoded proteins YIR041W YIR041W similarity to members of the SRP1P/TIP1P family YIR042C YIR042C weak similarity to B.licheniformi hypothetical protein P20 YIR043C YIR043C strong similarity to family of COnserved Sequences COS YIR044C YIR044C strong similarity to family of COnserved Sequences COS YJL003W YJL003W weak similarity to hypothetical protein SPAC1486.08 S. pombe YJL007C YJL007C hypothetical protein YJL009W YJL009W questionable ORF YJL010C YJL010C weak similarity to C.elegans hypothetical protei ZK792.5 YJL011C YJL011C weak similarity to chicken hypothetical protein YJL012C VTC4 similarity to YPL019c and YFl004w YJL012C-A YJL012C-A similarity to S. bayanus YJL015C YJL015C questionable ORF YJL016W YJL016W weak similarity to hypothetical protein YNL278w and YLR187w YJL017W YJL017W weak similarity to YLR187w YJL018W YJL018W questionable ORF YJL019W YJL019W weak similarity to hypothetical protein C. elegans YJL020C BBC1 similarity to S.pombe hypothetical protein SPAC23A1.16 YJL022W YJL022W questionable ORF YJL027C YJL027C hypothetical protein YJL028W YJL028W hypothetical protein YJL032W YJL032W questionable ORF YJL037W YJL037W strong similarity to hypothetical protein YJL038c YJL038C YJL038C strong similarity to hypothetical protein YJL037w YJL043W YJL043W similarity to hypothetical protein YKR015c YJL046W YJL046W similarity to E.coli lipoate-protein ligase A YJL047C-A YJL047C-A similarity to S. bayanus YJL048C YJL048C similarity to hypothetical protein YBR273c YJL049W YJL049W similarity to PIR:T39496 hypothetical protein SPBC1604.18c S. pombe YJL051W YJL051W hypothetical protein YJL052C-A YJL052C-A similarity to S. bayanus YJL055W YJL055W similarity to R.fascians hypothetical protein 6 YJL057C IKS1 weak similarity to human P1/eIF-2a protein kinase YJL058C YJL058C strong similarity to hypothetical protein YBR270c YJL062W-A YJL062W-A similarity to S. bayanus YJL064W YJL064W hypothetical protein YJL066C MPM1 hypothetical protein YJL067W YJL067W questionable ORF YJL069C YJL069C similarity to C.elegans hypothetical protein YJL072C YJL072C similarity to PIR:T40665 hypothetical protein SPBC725.13c S. pombe YJL075C YJL075C questionable ORF YJL077C ICS3 hypothetical protein YJL082W IML2 strong similarity to hypothetical protein YKR018c YJL083W YJL083W similarity to hypothetical protein YKR019c YJL084C YJL084C similarity to hypothetical protein YKR021w YJL086C YJL086C questionable ORF YJL091C YJL091C weak similarity to human G protein-coupled receptor YJL097W YJL097W similarity to hypothetical C. elegans protein T15B7.2 YJL100W LSB6 similarity to hypothetical C. elegans protein C56A3.8 YJL104W MIA1 weak similarity to C.elegans hypothetical protein F45G2.c YJL105W YJL105W similarity to hypothetical protein YKR029c YJL107C YJL107C similarity to hypothetical S. pombe protein YJL108C PRM10 strong similarity to hypothetical S. pombe protein YJL109C YJL109C weak similarity to ATPase DRS2P YJL112W MDV1 similarity to MET30P and N.crassa sulfur controller-2 YJL118W YJL118W hypothetical protein YJL119C YJL119C questionable ORF YJL120W YJL120W questionable ORF YJL122W YJL122W weak similarity to dog-fish transition protein S2 YJL123C YJL123C weak similarity to D.melanogaster troponin T and human nucleolin YJL127W-A YJL127W-A similarity to S. bayanus YJL131C YJL131C weak similarity to nonepidermal Xenopus keratin, type I YJL135W YJL135W questionable ORF YJL136W-A YJL136W-A hypothetical protein - identified by SAGE YJL142C YJL142C questionable ORF YJL144W YJL144W hypothetical protein YJL147C YJL147C weak similarity to C.elegans hypothetical protein C43G2.4 YJL149W YJL149W similarity to hypothetical protein YDR131c YJL150W YJL150W questionable ORF YJL151C SNA3 similarity to hypothetical protein SNA4/YDL123w YJL152W YJL152W questionable ORF YJL156W-A YJL156W-A similarity to S. bayanus YJL161W YJL161W hypothetical protein YJL162C YJL162C weak similarity to dnaJ proteins YJL163C YJL163C similarity to TRCDSEMBLNEW:AE003496_9 hypothetical protein CG15890 D. melanogaster YJL169W YJL169W questionable ORF YJL171C YJL171C similarity to YBR162c YJL175W YJL175W questionable ORF YJL178C YJL178C hypothetical protein YJL181W YJL181W similarity to hypothetical protein YJR030c YJL182C YJL182C questionable ORF YJL184W YJL184W hypothetical protein YJL185C YJL185C hypothetical protein YJL188C BUD19 questionable ORF YJL192C YJL192C hypothetical protein YJL195C YJL195C questionable ORF YJL199C YJL199C hypothetical protein YJL202C YJL202C questionable ORF YJL204C YJL204C weak similarity to TOR2P YJL207C YJL207C weak similarity to rat omega-conotoxin-sensitive calcium channel alpha-1 subunit rbB-I YJL211C YJL211C questionable ORF YJL213W YJL213W similarity to Methanobacterium aryldialkylphosphatase related protein YJL215C YJL215C hypothetical protein YJL217W YJL217W similarity to conserved hypothetical protein VCA0345 Vibrio cholerae YJL220W YJL220W questionable ORF YJL225C YJL225C strong similarity to members of the SIR1P/TIP1P family YJR003C YJR003C hypothetical protein YJR008W YJR008W similarity to S.pombe hypothetical protein YJR011C YJR011C hypothetical protein YJR012C YJR012C weak similarity to hypothetical protein B17C10.80 N. crassa YJR013W YJR013W similarity to C.elegans B0491.1 protein YJR014W YJR014W strong similarity to S.pombe hypothetical protein SPBC16C6.05 YJR018W YJR018W questionable ORF YJR020W YJR020W questionable ORF YJR024C YJR024C weak similarity to C.elegans Z49131_E ZC373.5 protein YJR025C-A YJR025C-A hypothetical protein - C-terminal part of YJR030c YJR030C YJR030C similarity to hypothetical protein YJL181w YJR037W YJR037W questionable ORF YJR038C YJR038C questionable ORF YJR039W YJR039W hypothetical protein YJR041C YJR041C weak similarity to hypothetical protein SPAC2G11.02 S. pombe YJR044C YJR044C weak similarity to putative transport protein YKR103w YJR054W YJR054W similarity to hypothetical protein YML047c YJR056C YJR056C hypothetical protein YJR061W YJR061W similarity to MNN4P YJR067C YAE1 similarity to S. pombe SPAC2C4.12c putative phosphotransferase YJR070C YJR070C similarity to C.elegans hypothetical protein C14A4.1 YJR071W YJR071W questionable ORF YJR072C YJR072C strong similarity to C.elegans hypothetical protein and similarity to YLR243w YJR079W YJR079W questionable ORF YJR080C YJR080C hypothetical protein YJR082C YJR082C hypothetical protein YJR083C YJR083C hypothetical protein YJR084W YJR084W weak similarity to S.pombe hypothetical protein SPAC1B3.08 YJR085C YJR085C similarity to hypothetical protein S.pombe YJR087W YJR087W questionable ORF YJR088C YJR088C weak similarity to S.pombe hypothetical protein SPBC14C8.18c YJR098C YJR098C weak similarity to Bacillus licheniformis esterase YJR100C YJR100C weak similarity to BUD3P YJR101W RSM26 weak similarity to superoxide dismutases YJR102C VPS25 weak similarity to hypothetical protein D. melanogaster YJR108W ABM1 similarity to hypothetical protein YIL014c-a YJR111C YJR111C weak similarity to E.coli colanic acid biosynthesis positive regulator RcsB YJR114W YJR114W questionable ORF YJR115W YJR115W similarity to hypothetical protein YBL043w YJR116W YJR116W similarity to hypothetical protein YPR114w YJR118C ILM1 weak similarity to Helicobacter pylori UreD protein YJR120W YJR120W hypothetical protein YJR128W YJR128W questionable ORF YJR129C YJR129C weak similarity to hypothetical protein YNL024c YJR136C YJR136C weak similarity to human 3',5'-cyclic-GMP phosphodiesterase YJR141W YJR141W weak similarity to hypothetical protein SPBC1734.10c S. pombe YJR146W YJR146W questionable ORF YJR154W YJR154W similarity to FUM9 Gibberella moniliformis fumonisin biosynthetic gene cluster YJR157W YJR157W hypothetical protein YJR161C COS5 strong similarity to subtelomeric encoded proteins YJR162C YJR162C strong similarity to subtelomeric encoded proteins YKL014C YKL014C similarity to hypothetical protein SPCC14G10.02 S. pombe YKL018C-A YKL018C-A similarity to S. bayanus YKL018W SWD2 similarity to C.elegans hypothetical protein YKL023W YKL023W weak similarity to human cylicin II YKL030W YKL030W questionable ORF YKL031W YKL031W hypothetical protein YKL033W YKL033W similarity to hypothetical protein S. pombe YKL034W YKL034W weak similarity to YOL013c YKL036C YKL036C questionable ORF YKL037W YKL037W weak similarity to C.elegans ubc-2 protein YKL044W YKL044W hypothetical protein YKL046C YKL046C strong similarity to YMR238w YKL047W YKL047W hypothetical protein YKL050C YKL050C similarity to YMR031c YKL051W YKL051W weak similarity to hypothetical protein S. pombe YKL052C ASK1 similarity to hypothetical protein S.pombe YKL053C-A YKL053C-A similarity to C.elegans hypothetical protein T09A5.7 (12.5 kD) YKL053W YKL053W questionable ORF YKL054C VID31 similarity to glutenin, high molecular weight chain proteins and SNF5P YKL059C YKL059C similarity to C.elegans hypothetical protein YKL061W YKL061W hypothetical protein YKL063C YKL063C weak similarity to mammalian microtubule-associated protein MAP 1B YKL066W YKL066W hypothetical protein YKL069W YKL069W strong similarity to hypothetical E.coli protein b1832 YKL071W YKL071W weak similarity to A.parasiticus nor-1 protein YKL075C YKL075C hypothetical protein YKL076C YKL076C questionable ORF YKL077W YKL077W hypothetical protein YKL082C YKL082C weak similarity to C.elegans hypothetical protein YKL083W YKL083W questionable ORF YKL084W YKL084W strong similarity to S.pombe hypothetical protein SPAC29B12 YKL086W YKL086W strong similarity to PIR:T39259 hypothetical protein S. pombe YKL090W YKL090W hypothetical protein YKL091C YKL091C strong similarity to SEC14P YKL094W YJU3 weak similarity to E.coli hypothetical protein YKL097C YKL097C hypothetical protein YKL098W YKL098W weak similarity to cellulase (EC 3.2.1.4) - Clostridium sp. YKL099C YKL099C similarity to C.elegans hypothetical proteins C18G6.06 and C16C10.2 YKL100C YKL100C similarity to C.elegans hypothetical protein YKL102C YKL102C hypothetical protein YKL105C YKL105C similarity to YMR086w YKL106C-A YKL106C-A similarity to S. bayanus YKL107W YKL107W weak similarity to S.antibioticus probable oxidoreductase YKL111C YKL111C questionable ORF YKL115C YKL115C questionable ORF YKL118W YKL118W questionable ORF YKL121W YKL121W strong similarity to YMR102c YKL123W YKL123W questionable ORF YKL131W YKL131W questionable ORF YKL133C YKL133C similarity to hypothetical protein YMR115w YKL136W YKL136W questionable ORF YKL137W YKL137W weak similarity to hypothetical protein F1N13_200 - A. thaliana YKL147C YKL147C questionable ORF YKL151C YKL151C similarity to C.elegans hypothetical protein R107.2 YKL153W YKL153W questionable ORF YKL155C RSM22 similarity to S. pombe SPAC1420.04c putative cytochrome c oxidase assembly protein YKL158W YKL158W hypothetical protein YKL160W YKL160W similarity to hypothetical S. pombe protein YKL162C YKL162C hypothetical protein YKL162C-A YKL162C-A questionable ORF - identified by SAGE YKL165C-A YKL165C-A similarity to S. bayanus YKL169C YKL169C questionable ORF YKL177W YKL177W questionable ORF YKL183W LOT5 hypothetical protein YKL187C YKL187C strong similarity to hypothetical protein YLR413w YKL195W YKL195W similarity to rabbit histidine-rich calcium-binding protein YKL202W YKL202W questionable ORF YKL206C YKL206C hypothetical protein YKL207W YKL207W similarity to conserved hypothetical transmembrane protein S.pombe YKL214C YKL214C weak similarity to mouse transcriptional coactivator ALY YKL219W COS9 similarity to subtelomeric encoded proteins YKL223W YKL223W strong similarity to subtelomeric encoded proteins YKL224C YKL224C strong similarity to members of the SRP1P/TIP1P family YKL225W YKL225W strong similarity to GIN11P, YKL225w and other subtelomeric encoded proteins YKR005C YKR005C hypothetical protein YKR007W YKR007W weak similarity to Streptococcus protein M5 precursor YKR011C TOS5 hypothetical protein YKR012C YKR012C questionable ORF YKR013W PRY2 similarity to the plant PR-1 class of pathogen related proteins YKR015C YKR015C similarity to hypothetical protein YJL043w YKR017C YKR017C similarity to human hypothetical KIAA0161 protein YKR018C YKR018C strong similarity to hypothetical protein YJL082w YKR020W YKR020W hypothetical protein YKR021W YKR021W strong similarity to hypothetical protein YJL084c YKR022C YKR022C hypothetical protein YKR023W YKR023W similarity to S.pombe hypothetical protein SPAC23C4 YKR029C YKR029C similarity to YJL105w and Lentinula MFBA protein YKR030W YKR030W weak similarity to NADH dehydrogenases YKR032W YKR032W hypothetical protein YKR033C YKR033C questionable ORF YKR040C YKR040C questionable ORF YKR041W YKR041W hypothetical protein YKR044W YKR044W hypothetical protein YKR045C YKR045C hypothetical protein YKR047W YKR047W questionable ORF YKR049C YKR049C hypothetical protein YKR051W YKR051W similarity to C.elegans hypothetical protein YKR060W YKR060W similarity to hypothetical protein S. pombe YKR065C YKR065C similarity to hypothetical protein S. pombe YKR070W YKR070W strong similarity to S. pombe phosphatidyl synthase YKR071C DRE2 weak similarity to C.elegans hypothetical protein YKR073C YKR073C hypothetical protein YKR074W YKR074W strong similarity to hypothetical S. pombe protein YKR075C YKR075C weak similarity to negative regulator REG1P YKR077W YKR077W hypothetical protein YKR078W YKR078W similarity to VPS5P YKR079C YKR079C similarity to S.pombe hypothetical protein SPAC1D4.10 YKR081C YKR081C strong similarity to hypothetical protein S. pombe YKR083C DAD2 weak similarity to S.japonicum paramyosin YKR087C YKR087C similarity to hypothetical Myxococcus xanthus protein YKR088C YKR088C weak similarity to b.subtilis spore germination protein II YKR089C YKR089C strong similarity to YOR081c YKR090W YKR090W similarity to chicken Lim protein kinase and Islet proteins YKR091W SRL3 similarity to YOR083w YKR100C YKR100C similarity to hypothetical protein YIL158w YLL005C SPO75 similarity to A.thaliana hyp1 protein YLL007C YLL007C hypothetical protein YLL014W YLL014W hypothetical protein YLL018C-A COX19 similarity to hypothetical S. pombe protein (YEB7) YLL020C YLL020C questionable ORF YLL023C YLL023C similarity to hypothetical protein YLR064w YLL025W YLL025W strong similarity to members of the SRP1P/TIP1P family YLL029W YLL029W similarity to M.jannaschii X-Pro dipeptidase and S.pombe hypothetical protein YLL030C YLL030C hypothetical protein YLL032C YLL032C similarity to hypothetical protein SPAC9B6.13 S. pombe YLL033W YLL033W hypothetical protein YLL035W GRC3 similarity to S. pombe SPCC830.03 protein of unknown function YLL037W YLL037W weak similarity to human platelet-activating factor receptor YLL038C ENT4 weak similarity to YJR125c and YDL161w YLL049W YLL049W hypothetical protein YLL056C YLL056C weak similarity to Y.pseudotuberculosis CDP-3,6-dideoxy-D-glycero-L-glycero-4-hexulose-5-epimerase YLL059C YLL059C hypothetical protein YLL062C MHT1 weak similarity to M.leprae metH2 protein YLL063C AYT1 strong similarity to Gibberella zeae trichothecene 3-O-acetyltransferase YLL064C YLL064C strong similarity to members of the SRP1/TIP1P family YLL065W GIN11 strong similarity to YJR162c, YNR077c, YKL225w and other subtelomeric encoded proteins YLL066C YLL066C strong similarity to subtelomeric encoded proteins YLL067C YLL067C strong similarity to subtelomeric encoded proteins YLR001C YLR001C weak similarity to hypothetical protein SPAC22H12.05c S. pombe YLR003C YLR003C weak similarity to PIR:T39953 hypothetical protein SPBC23G7.07c S. pombe YLR007W YLR007W hypothetical protein YLR008C YLR008C similarity to hypothetical protein YNL328c YLR011W LOT6 weak similarity to E.coli hypothetical 20.4 kDa protein YLR012C YLR012C hypothetical protein YLR015W BRE2 weak similarity to S.pombe hypothetical protein SPBC13G1 YLR016C YLR016C weak similarity to TRCDSEMBLNEW:AK022615_1 unnamed ORF; Homo sapiens YLR021W YLR021W hypothetical protein YLR022C YLR022C similarity to C.elegans and M.jannaschii hypothetical proteins YLR023C YLR023C similarity to S.pombe hypothetical protein SPAC30D11.11 YLR024C UBR2 similarity to ubiquitin--protein ligase UBR1P YLR030W YLR030W hypothetical protein YLR031W YLR031W similarity to hypothetical protein YMR124w YLR033W RSC58 hypothetical protein YLR036C YLR036C similarity to YIL089w YLR040C YLR040C weak similarity to hypothetical protein YIL011w YLR041W YLR041W questionable ORF YLR042C YLR042C hypothetical protein YLR047C YLR047C similarity to hypothetical protein YGL160w YLR049C YLR049C hypothetical protein YLR050C YLR050C weak similarity to human MAC30 C-terminus YLR051C YLR051C similarity to human acidic 82 kDa protein YLR052W IES3 hypothetical protein YLR053C YLR053C hypothetical protein YLR054C YLR054C hypothetical protein YLR057W YLR057W weak similarity to mouse alpha-mannosidase YLR062C BUD28 questionable ORF YLR064W YLR064W weak similarity to Anopheles NADH-ubiquinone oxidoreductase, chain 4 YLR065C YLR065C weak similarity to hypothetical protein A. thaliana YLR068W FYV7 hypothetical protein YLR072W YLR072W similarity to YFL042c, YDR326c and YHR080c YLR073C YLR073C weak similarity to hypothetical protein S. pombe YLR074C BUD20 weak similarity to human zinc finger protein YLR076C YLR076C questionable ORF YLR077W YLR077W weak similarity to Xenopus RCC1 protein YLR082C SRL2 weak similarity to phospholipase C YLR084C RAX2 weak similarity to PST1P YLR087C CSF1 weak similarity to hypothetical protein D. melanogaster YLR091W YLR091W hypothetical protein YLR094C GIS3 hypothetical protein YLR095C IOC2 weak similarity to hypothetical protein C. elegans YLR097C YLR097C weak similarity to H. sapiens F-box protein YLR099W-A YLR099W-A similarity to S. bayanus YLR101C YLR101C questionable ORF YLR104W YLR104W hypothetical protein YLR106C YLR106C similarity to Kaposi's sarcoma-associated herpes-like virus ORF73 homolog gene YLR108C YLR108C strong similarity to YDR132c YLR111W YLR111W hypothetical protein YLR112W YLR112W hypothetical protein YLR114C EFR4 similarity to C.elegans hypothetical protein and YOR054c YLR122C YLR122C hypothetical protein YLR123C YLR123C questionable ORF YLR124W YLR124W hypothetical protein YLR125W YLR125W hypothetical protein YLR128W YLR128W similarity to S.pombe hypothetical protein SPBC24E9 YLR132C YLR132C hypothetical protein YLR135W SLX4 subunit of SLX1P/Ybr228p-SLX4P complex, required for cell growth in the absence of SGS1 or TOP3 YLR137W YLR137W weak similarity to hypothetical S.pombe protein SPCC4G3 YLR140W YLR140W questionable ORF YLR143W YLR143W weak similarity to Pyrococcus horikoshii hypothetical protein PHBJ017 YLR145W YLR145W hypothetical protein YLR149C YLR149C weak similarity to hypothetical protein SPCC4G3.03 S. pombe YLR149C-A YLR149C-A similarity to S. bayanus YLR152C YLR152C similarity to YOR3165w and YNL095c YLR154C YLR154C hypothetical protein YLR156W YLR156W identical to hypothetical proteins YLR161w and YLR159w YLR159W YLR159W identical to hypothetical proteins YLR161w and YLR156w YLR161W YLR161W identical to hypothetical proteins YLR156w and YLR159w YLR162W YLR162W hypothetical protein YLR169W YLR169W questionable ORF YLR171W YLR171W questionable ORF YLR173W YLR173W hypothetical protein YLR177W YLR177W similarity to suppressor protein Psp5p YLR181C YLR181C hypothetical protein YLR183C TOS4 similarity to YDR501w YLR184W YLR184W weak similarity to ribulose-bisphosphate carboxylase YLR186W EMG1 strong similarity to S.pombe hypothetical protein C18G6.07C YLR187W YLR187W similarity to hypothetical protein YNL278w YLR190W YLR190W hypothetical protein YLR194C YLR194C hypothetical protein YLR196W PWP1 similarity to human IEF SSP 9502 protein YLR198C YLR198C questionable ORF YLR199C YLR199C hypothetical protein YLR201C YLR201C similarity to hypothetical S. pombe protein YLR202C YLR202C questionable ORF YLR204W QRI5 weak similarity to YOR309c YLR211C YLR211C hypothetical protein YLR213C CRR1 similarity to CRH1P cell wall protein YLR217W YLR217W questionable ORF YLR218C YLR218C similarity to PIR:T41376 hypothetical protein S. pombe YLR219W MSC3 hypothetical protein YLR221C RSA3 hypothetical protein YLR222C CST29 similarity to DIP2P YLR224W YLR224W hypothetical protein YLR225C YLR225C strong similarity to YDR222w YLR227C ADY4 hypothetical protein YLR230W YLR230W questionable ORF YLR232W YLR232W questionable ORF YLR235C YLR235C questionable ORF YLR236C YLR236C hypothetical protein YLR238W YLR238W similarity to YDR200c YLR241W YLR241W similarity to hypothetical S.pombe protein SPAC2G11.09 YLR243W YLR243W strong similarity to YOR262w YLR247C YLR247C similarity to S.pombe rad8 protein and RDH54P YLR252W YLR252W questionable ORF YLR253W YLR253W weak similarity to bacterial aminoglycoside acetyltransferase regulators YLR254C YLR254C weak similarity to PIR:T10472 G-box binding protein 2A Sinapis alba YLR255C YLR255C hypothetical protein YLR257W YLR257W hypothetical protein YLR261C YLR261C questionable ORF YLR262C-A YLR262C-A strong similarity to F49C12.11 (Z68227_K) from C. elegans YLR264C-A YLR264C-A hypothetical protein - identified by SAGE YLR265C NEJ1 hypothetical protein YLR267W BOP2 hypothetical protein YLR269C YLR269C questionable ORF YLR270W YLR270W strong similarity to YOR173w YLR271W YLR271W weak similarity to hypothetical protein T04H1.5 C. elegans YLR279W YLR279W questionable ORF YLR280C YLR280C questionable ORF YLR282C YLR282C questionable ORF YLR283W YLR283W weak similarity to SMC2P YLR285W YLR285W weak similarity to A.thaliana hypothetical protein YLR287C YLR287C weak similarity to S.pombe hypothetical protein SPAC22E12 YLR290C YLR290C similarity to hypothetical protein SPCC1840.09 S. pombe YLR294C YLR294C questionable ORF YLR296W YLR296W hypothetical protein YLR297W YLR297W weak similarity to Vibrio vulnificus VvpC protein YLR301W YLR301W hypothetical protein YLR302C YLR302C questionable ORF YLR311C YLR311C weak similarity to S.tarentolae cryptogene protein G4 YLR312C YLR312C hypothetical protein YLR315W YLR315W weak similarity to rat apolipoprotein A-IV YLR317W KRE34 questionable ORF YLR320W YLR320W hypothetical protein YLR322W YLR322W questionable ORF YLR323C YLR323C weak similarity to N.crassa uvs2 protein YLR324W YLR324W strong similarity to YGR004w YLR326W YLR326W hypothetical protein YLR328W YLR328W strong similarity to YGR010w YLR331C YLR331C questionable ORF YLR334C YLR334C questionable ORF YLR338W KRE21 questionable ORF YLR339C YLR339C questionable ORF YLR346C YLR346C weak similarity to YGR035c YLR349W YLR349W questionable ORF YLR350W YLR350W strong similarity to YGR038w YLR352W YLR352W hypothetical protein YLR358C YLR358C questionable ORF YLR361C YLR361C similarity to YOR3329c YLR363W-A YLR363W-A similarity to Z. rouxii YLR364W YLR364W weak similarity to GRX2 Homo sapiens glutaredoxin 2 YLR365W YLR365W weak similarity to Udf2p YLR366W YLR366W hypothetical protein YLR368W YLR368W weak similarity to Mus musculus F-box protein FBA YLR373C VID22 similarity to hypothetical protein Ygr071cp YLR374C YLR374C questionable ORF YLR376C YLR376C hypothetical protein YLR379W YLR379W questionable ORF YLR381W YLR381W hypothetical protein YLR385C YLR385C hypothetical protein YLR386W YLR386W similarity to hypothetical S. pombe protein YLR392C YLR392C hypothetical protein YLR397C AFG2 strong similarity to CDC48 YLR400W YLR400W hypothetical protein YLR401C YLR401C similarity to A.brasilense nifR3 protein YLR402W YLR402W hypothetical protein YLR404W YLR404W hypothetical protein YLR405W YLR405W similarity to A.brasilense nifR3 protein YLR407W YLR407W hypothetical protein YLR408C YLR408C weak similarity to probable topoisomerase VIA A. thaliana YLR412W YLR412W weak similarity to Candida maltosa cytochrome P450 YLR413W YLR413W strong similarity to YKL187c YLR414C YLR414C weak similarity to YLR413w YLR415C YLR415C questionable ORF YLR416C YLR416C hypothetical protein YLR421C RPN13 weak similarity to human 42K membrane glycoprotein YLR422W YLR422W similarity to human DOCK180 protein YLR424W YLR424W weak similarity to STU1P YLR425W TUS1 similarity to GDP-GTP exchange factors YLR426W YLR426W weak similarity to 3-oxoacyl-[acyl-carrier-protein] reductase from E. coli YLR427W YLR427W weak similarity to human transcription regulator Staf-5 YLR428C YLR428C questionable ORF YLR431C YLR431C weak similarity to rabbit trichohyalin YLR434C YLR434C questionable ORF YLR435W YLR435W similarity to hypothetical protein B23L21.160 - N. crassa YLR437C YLR437C hypothetical protein YLR440C YLR440C hypothetical protein YLR444C YLR444C questionable ORF YLR445W YLR445W hypothetical protein YLR446W YLR446W weak similarity to hexokinases YLR454W YLR454W similarity to YPR117w YLR455W YLR455W weak similarity to human G/T mismatch binding protein YLR456W YLR456W strong similarity to YPR172w YLR458W YLR458W questionable ORF YLR460C YLR460C similarity to C.carbonum toxD protein YLR462W YLR462W strong similarity to subtelomeric encoded proteins YLR463C YLR463C strong similarity to subtelomeric encoded proteins YLR464W YLR464W strong similarity to subtelomeric encoded proteins YLR465C YLR465C questionable ORF YLR467W YRF1-5 strong similarity to subtelomeric encoded proteins YML002W YML002W hypothetical protein YML003W YML003W hypothetical protein YML005W YML005W similarity to hypothetical S.pombe protein YML006C GIS4 hypothetical protein YML007C-A YML007C-A similarity to S. bayanus YML009C-A YML009C-A questionable ORF YML009W-B YML009W-B questionable ORF YML011C YML011C hypothetical protein YML012C-A YML012C-A questionable ORF YML013W YML013W hypothetical protein YML014W YML014W strong similarity to S.pombe hypothetical protein, similarity to C.elegans hypothetical protein YML018C YML018C similarity to YDR438w YML020W YML020W hypothetical protein YML023C YML023C weak similarity to NMD2P YML029W YML029W hypothetical protein YML030W YML030W weak similarity to CG9921 D. melanogaster YML031C-A YML031C-A questionable ORF YML034C-A YML034C-A questionable ORF YML034W SRC1 similarity to YDR458c YML036W YML036W weak similarity to C.elegans hypothetical protein CELW03F8 YML037C YML037C hypothetical protein YML038C YMD8 similarity to vanadate resistance protein GOG5P, member of the triose phosphate translocater family of membrane transporters YML041C YML041C weak similarity to probable cyclin G1 interacting protein S.pombe YML047C PRM6 strong similarity to YJR054w YML047W-A YML047W-A questionable ORF YML050W YML050W weak similarity to potato sucrose cleavage protein YML052W SUR7 similarity to YDL222c and YNL194c YML053C YML053C hypothetical protein YML057C-A YML057C-A questionable ORF YML059C YML059C similarity to C.elegans ZK370.4 protein YML066C SMA2 hypothetical protein YML068W YML068W similarity to C.elegans hypothetical protein YML071C DOR1 weak similarity to unnamed ORF Mus musculus brain cDNA YML072C YML072C similarity to YOR3141c and YNL087w YML079W YML079W weak similarity to Synechocystis sp. hypothetical protein sll1188 YML080W DUS1 similarity to A.brasilense nifR3 protein YML083C YML083C hypothetical protein YML084W YML084W hypothetical protein YML089C YML089C questionable ORF YML090W YML090W hypothetical protein YML093W YML093W similarity to P.falciparum liver stage antigen LSA-1 YML094C-A YML094C-A questionable ORF YML099W-A YML099W-A questionable ORF YML101C YML101C weak similarity to YMR264w YML101C-A YML101C-A questionable ORF YML107C YML107C hypothetical protein YML108W YML108W hypothetical protein YML116W-A YML116W-A questionable ORF YML117W YML117W similarity to YPL184c YML118W NGL3 similarity to YMR285c YML119W YML119W hypothetical protein YML122C YML122C hypothetical protein YML127W RSC9 weak similarity to LOS1P YML128C MSC1 weak similarity to S. pombe SPBC365.12c protein of unknown function YML132W COS3 strong similarity to subtelomeric encoded proteins YML133C YML133C strong similarity to other subtelomer encoded proteins YMR002W YMR002W similarity to hypothetical S.pombe and C.elegans proteins YMR003W YMR003W hypothetical protein YMR007W YMR007W hypothetical protein YMR009W YMR009W weak similarity to P.aeruginosa regulatory protein mmsR YMR010W YMR010W weak similarity to hypothetical protein YDR352w YMR013W-A YMR013W-A similarity to S. bayanus YMR014W BUD22 weak similarity to S.pombe hypothetical protein SPAC4F10 YMR025W YMR025W hypothetical protein YMR029C YMR029C weak similarity to human nuclear autoantigen YMR030W YMR030W hypothetical protein YMR031C YMR031C similarity to YKL050c and human restin YMR031W-A YMR031W-A questionable ORF YMR034C YMR034C weak similarity to YPR201w YMR040W YMR040W strong similarity to YET1P YMR041C YMR041C weak similarity to Pseudomonas L-fucose dehydrogenase YMR044W IOC4 weak similarity to S. pombe SPBC29A3.13 and CRN1 Coronin-like protein YMR046W-A YMR046W-A questionable ORF - identified by SAGE YMR048W CSM3 weak similarity to unnamed ORF; Homo sapiens cDNA YMR049C ERB1 weak similarity to A.thaliana PRL1 protein YMR052C-A YMR052C-A questionable ORF YMR057C YMR057C hypothetical protein YMR066W SOV1 hypothetical protein YMR067C YMR067C weak similarity to hypothetical protein D. melanogaster YMR068W YMR068W weak similarity to mouse transcription factor NF-kappaB YMR069W YMR069W weak similarity hypothetical protein S. pombe YMR071C YMR071C similarity to hypothetical protein S. pombe YMR074C YMR074C strong similarity to hypothetical S. pombe protein YMR075C-A YMR075C-A questionable ORF YMR075W YMR075W weak similarity to human Mi-2 protein YMR082C YMR082C hypothetical protein YMR084W YMR084W strong similarity to GFA1P - putative pseudogene YMR085W YMR085W strong similarity to GFA1P - putative pseudogene YMR086C-A YMR086C-A questionable ORF YMR086W YMR086W similarity to YKL105c YMR087W YMR087W hypothetical protein YMR090W YMR090W strong similarity to B. subtilis conserved hypothetical protein yhfK YMR093W YMR093W weak similarity to PWP2P YMR097C YMR097C weak similarity to M.genitalium hypothetical protein homolog MG442 YMR098C YMR098C hypothetical protein YMR102C YMR102C strong similarity to YKL121w YMR103C YMR103C hypothetical protein YMR107W YMR107W hypothetical protein YMR111C YMR111C weak similarity to MSN1 protein YMR114C YMR114C similarity to B. subtilis conserved hypothetical proteins yoqW and yoaM YMR115W YMR115W similarity to YKL133c YMR119W ASI1 similarity to YNL008c YMR119W-A YMR119W-A questionable ORF YMR122C YMR122C hypothetical protein YMR122W-A YMR122W-A hypothetical protein - identified by SAGE YMR124W YMR124W weak similarity to YLR031w YMR126C YMR126C hypothetical protein YMR130W YMR130W similarity to D.melanogaster Dreg-2 protein YMR132C YMR132C similarity to hypothetical S. pombe protein YMR134W YMR134W hypothetical protein YMR135C YMR135C weak similarity to conserved hypothetical protein S. pombe YMR135W-A YMR135W-A questionable ORF YMR136W GAT2 weak similarity to YIR013c and YLR013w YMR140W YMR140W similarity to probable zinc finger protein S. pombe YMR141C YMR141C hypothetical protein YMR144W YMR144W weak similarity to MLP1P YMR147W YMR147W hypothetical protein YMR148W YMR148W hypothetical protein YMR151W YIM2 hypothetical protein YMR153C-A YMR153C-A questionable ORF YMR155W YMR155W weak similarity to E.coli hypothetical protein f402 YMR156C TPP1 similarity to mammalian polynucleotide kinase 3'-phosphatase YMR157C YMR157C hypothetical protein YMR158C-A YMR158C-A questionable ORF - identified by SAGE YMR158W YMR158W weak similarity to E.coli ribosomal S8 protein YMR158W-B YMR158W-B questionable ORF YMR160W YMR160W weak similarity to fruit fly ecdysone-inducible protein YMR163C YMR163C hypothetical protein YMR171C YMR171C similarity to YKL124w YMR172C-A YMR172C-A questionable ORF YMR172W HOT1 similarity to MSN1 protein YMR173W-A YMR173W-A questionable ORF YMR178W YMR178W similarity to C.elegans hypothetical protein YMR181C YMR181C similarity to YPL229w YMR184W YMR184W hypothetical protein YMR185W YMR185W similarity to hypothetical protein S. pombe YMR187C YMR187C hypothetical protein YMR191W YMR191W hypothetical protein YMR192W YMR192W similarity to mouse Tbc1 protein YMR193C-A YMR193C-A questionable ORF YMR194C-A YMR194C-A hypothetical protein - identified by SAGE YMR195W ICY1 similarity to ICY2 YMR196W YMR196W strong similarity to hypothetical protein Neurospora crassa YMR204C YMR204C weak similarity to D.melanogaster hypothetical protein DMC39E1 YMR206W YMR206W weak similarity to hypothetical protein YNR014w YMR209C YMR209C similarity to conserved hypothetical protein S. pombe YMR210W YMR210W similarity to P.glauca late embryogenesis abundant protein and YBR177c and YPL095c YMR211W YMR211W weak similarity to beta tubulins YMR212C EFR3 weak similarity to myosins, conserved, ubiquitous membrane protein required for cell viability YMR215W YMR215W similarity to GAS1 protein YMR216C SKY1 similarity to S.pombe dsk1, human SRPK1 and other protein kinases YMR221C YMR221C weak similarity to photosystem II protein D2 YMR233W YMR233W strong similarity to YOR295w YMR244C-A YMR244C-A questionable ORF YMR245W YMR245W weak similarity to mouse thyrotropin-releasing hormone receptor YMR247C YMR247C similarity to hypothetical protein S. pombe YMR251W YMR251W strong similarity to YKR076w and YGR154c YMR252C YMR252C hypothetical protein YMR253C YMR253C strong similarity to YPL264c YMR254C YMR254C hypothetical protein YMR258C YMR258C hypothetical protein YMR259C YMR259C similarity to hypothetical protein S. pombe YMR265C YMR265C weak similarity to hypothetical protein S. pombe YMR266W RSN1 similarity to A.thaliana hyp1 protein YMR269W YMR269W weak similarity to C.elegans hypothetical protein CELT23B3 YMR289W YMR289W weak similarity to para-aminobenzoate synthase component I (EC 4.1.3.-) Campylobacter jejuni YMR290W-A YMR290W-A questionable ORF YMR291W YMR291W similarity to ser/thr protein kinase YMR294W-A YMR294W-A questionable ORF YMR295C YMR295C similarity to YGR273c YMR298W YMR298W hypothetical protein YMR299C YMR299C weak similarity to hypothetical protein YJL062w YMR304C-A YMR304C-A questionable ORF YMR306C-A YMR306C-A questionable ORF YMR310C YMR310C similarity to YGR283c YMR313C YMR313C similarity to YKR089c and YOR081c YMR315W YMR315W similarity to hypothetical S. pombe protein YMR316C-A YMR316C-A questionable ORF YMR316C-B YMR316C-B questionable ORF YMR316W DIA1 similarity to YOR385w and YNL165w YMR320W YMR320W hypothetical protein YMR321C YMR321C strong similarity to hypothetical proteins YPL273w and YLL062c YMR322C YMR322C strong similarity to YPL280w, YOR391c and YDR533c YMR324C YMR324C strong similarity to YBL108w, YCR103c and YKL223w YMR325W YMR325W strong similarity to members of the SRP1P/TIP1P family YMR326C YMR326C strong similarity to subtelomeric encoded proteins YNL008C ASI3 similarity to YMR119w YNL010W YNL010W weak similarity to B.subtilis hypothetical protein ykrX YNL011C YNL011C similarity to hypothetical A. thaliana protein T14G11.21 YNL013C YNL013C questionable ORF YNL017C YNL017C hypothetical protein YNL018C YNL018C strong similarity to hypothetical protein YNL034w YNL019C YNL019C strong similarity to YNL033w YNL022C YNL022C weak similarity to C.burnetii FMU protein YNL024C YNL024C weak similarity to YBR271w and YJR129c YNL026W YNL026W similarity to S.pombe hypothetical protein YNL028W YNL028W questionable ORF YNL032W SIW14 similarity to YNL099c, YNL056w and YDR067c YNL033W YNL033W strong similarity to YNL019c YNL034W YNL034W strong similarity to YNL018c YNL035C YNL035C similarity to hypothetical protein S. pombe YNL038W GPI15 sequence and functional homologue of human Pig-H protein YNL041C TFI2 weak similarity to MLP1 YNL042W BOP3 hypothetical protein YNL043C YNL043C questionable ORF YNL046W YNL046W hypothetical protein YNL047C YNL047C similarity to probable transcription factor ASK10P and hypothetical protein YPR115w, and strong similarity to hypothetical protein YIL105c YNL049C SFB2 strong similarity to YIL109c YNL050C YNL050C hypothetical protein YNL051W COD4 weak similarity to hypothetical protein Drosophila melanogaster YNL056W YNL056W similarity to YNL032w and YNL099c YNL057W YNL057W questionable ORF YNL058C YNL058C similarity to YIL117c YNL063W YNL063W weak similarity to Mycoplasma protoporphyrinogen oxidase YNL067W-A YNL067W-A similarity to S. bayanus YNL074C MLF3 similarity to YIL135c YNL078W JIP1 hypothetical protein YNL080C YNL080C hypothetical protein YNL086W YNL086W hypothetical protein YNL087W YNL087W weak similarity to synaptogamines YNL089C YNL089C questionable ORF YNL091W YNL091W similarity to chicken h-caldesmon, USO1P and YKL201c YNL092W YNL092W similarity to hypothetical C. elegans proteins Y48E1C.2 and Y48E1C.c YNL094W YNL094W similarity to S.pombe hypothetical protein YNL095C YNL095C strong similarity to YOR092w YNL099C YNL099C similarity to YNL032w, YNL056w and YDR067c YNL100W YNL100W hypothetical protein YNL101W YNL101W similarity to YKL146w YNL105W YNL105W questionable ORF YNL108C YNL108C strong similarity to YOR110w YNL109W YNL109W weak similarity to cytochrome-c oxidase YNL110C YNL110C weak similarity to fruit fly RNA-binding protein YNL114C YNL114C questionable ORF YNL115C YNL115C weak similarity to S.pombe hypothetical protein SPAC23C11 YNL116W YNL116W weak similarity to RING zinc finger protein from Gallus gallus YNL120C YNL120C questionable ORF YNL122C YNL122C hypothetical protein YNL123W YNL123W weak similarity to C.jejuni serine protease YNL124W YNL124W similarity to hypothetical S. pombe protein YNL127W YNL127W similarity to C.elegans hypothetical protein YNL129W YNL129W weak similarity to M.pneumoniae uridine kinase udk YNL133C FYV6 hypothetical protein YNL136W YNL136W similarity to neurofilament triplet M protein YNL140C YNL140C questionable ORF YNL143C YNL143C hypothetical protein YNL144C YNL144C similarity to YHR131c YNL146W YNL146W hypothetical protein YNL149C YNL149C weak similarity to S.pombe hypothetical protein YNL150W YNL150W hypothetical protein YNL152W YNL152W similarity to hypothetical protein S. pombe YNL155W YNL155W similarity to unnamed ORF; Homo sapiens cDNA YNL156C YNL156C similarity to YHR133c YNL157W YNL157W weak similarity to S.pombe hypothetical protein SPAC10F6 YNL158W YNL158W hypothetical protein YNL159C ASI2 hypothetical protein YNL162W-A YNL162W-A similarity to K. marxianus YNL164C YNL164C hypothetical protein YNL165W YNL165W similarity to YOR385w and YMR316w YNL166C BNI5 similarity to S. pombe SPBC1711.05 serine-rich repeat protein of unknown function YNL168C YNL168C similarity to C.elegans ZK688.3 protein and E.coli hpcEp YNL170W YNL170W questionable ORF YNL171C YNL171C questionable ORF YNL174W YNL174W hypothetical protein YNL176C YNL176C weak similarity to HKR1P YNL177C YNL177C similarity to hypothetical protein S. pombe YNL179C YNL179C hypothetical protein YNL181W YNL181W similarity to hypothetical S. pombe protein YNL182C YNL182C weak similarity to S.pombe hypothetical protein YNL184C YNL184C questionable ORF YNL187W YNL187W hypothetical protein YNL190W YNL190W weak similarity to MUCIN 1 PRECURSOR Mesocricetus auratus (Golden hamster) YNL191W YNL191W similarity to Synechocystis hypothetical protein YNL193W YNL193W weak similarity to hypothetical protein S. pombe YNL194C YNL194C strong similarity to YDL222c and similarity to SUR7P YNL195C YNL195C hypothetical protein YNL198C YNL198C questionable ORF YNL200C YNL200C strong similarity to human TGR-CL10C YNL203C YNL203C weak similarity to B.subtilis CDP-diacylglycerol--serine O-phosphatidyltransferase YNL205C YNL205C questionable ORF YNL207W YNL207W similarity to M.jannaschii hypothetical protein MJ1073 YNL208W YNL208W weak similarity to Colletotrichum gloeosporioides nitrogen starvation-induced glutamine rich protein YNL211C YNL211C hypothetical protein YNL212W VID27 weak similarity to C.cardunculus cypro4 protein YNL215W IES2 similarity to hypothetical S. pombe protein YNL224C YNL224C similarity to hypothetical protein S. pombe YNL226W YNL226W questionable ORF YNL228W YNL228W questionable ORF YNL230C ELA1 weak similarity to mammalian transcription elongation factor elongin A YNL234W YNL234W weak similarity to mouse hemoglobin zeta chain YNL235C YNL235C questionable ORF YNL240C NAR1 similarity to human nuclear prelamin A recognition factor YNL245C YNL245C similarity to hypothetical protein CG2843 D. melanogaster YNL249C MPA43 similarity to YDR109c YNL253W YNL253W similarity to hypothetical protein C. elegans YNL254C YNL254C hypothetical protein YNL258C YNL258C hypothetical protein YNL260C YNL260C weak similarity to hypothetical protein S. pombe YNL265C IST1 similarity to NUF1P, has a role in resistance to high concentrations of sodium YNL266W YNL266W questionable ORF YNL269W YNL269W hypothetical protein YNL276C YNL276C questionable ORF YNL278W CAF120 similarity to YLR187w YNL279W PRM1 similarity to S. pombe coiled-coil protein of unknown function YNL281W HCH1 strong similarity to YDR214w YNL285W YNL285W hypothetical protein YNL288W CAF40 strong similarity to C.elegans hypothetical protein YNL293W MSB3 similarity to Mic1p and human transforming protein tre-2, and strong similarity to YOL112w YNL294C YNL294C similarity to TRCDSEMBL:AF152926_1 palH Emericella nidulans YNL295W YNL295W hypothetical protein YNL296W KRE25 questionable ORF YNL297C MON2 similarity to S.pombe hypothetical protein SPAC23D3.13c YNL300W TOS6 similarity to MID2P YNL303W YNL303W hypothetical protein YNL305C YNL305C similarity to C-term. of A.nidulans regulatory protein (qutR) YNL308C KRI1 similarity to S.pombe and C.elegans hypothetical proteins YNL310C YNL310C similarity to S.pombe hypothetical protein SPAC24H6.02c YNL311C YNL311C hypothetical protein YNL313C YNL313C similarity to C.elegans hypothetical protein YNL319W YNL319W questionable ORF YNL321W YNL321W weak similarity to VCX1P YNL323W LEM3 similarity to Ycx1p YNL324W YNL324W hypothetical protein YNL326C YNL326C similarity to YOL003c, YLR246w and C.elegans hypothetical protein ZK757.1 YNL336W COS1 strong similarity to subtelomeric encoded proteins YNL337W YNL337W strong similarity to subtelomeric encoded proteins YNL338W YNL338W strong similarity to subtelomeric encoded poteins YNR001W-A YNR001W-A similarity to S. bayanus YNR004W YNR004W weak similarity to bovine interferon gamma precursor YNR005C YNR005C questionable ORF YNR009W YNR009W hypothetical protein YNR014W YNR014W weak similarity to hypothetical protein YMR206w YNR018W YNR018W similarity to TRCDSEMBL:SPAC1565_1 hypothetical protein S. pombe YNR020C YNR020C similarity to hypothetical metalloproteinase S. pombe YNR021W YNR021W weak similarity to hypothetical protein S. pombe YNR022C YNR022C weak similarity to protein phosphatases YNR024W YNR024W weak similarity to RPC31P YNR025C YNR025C questionable ORF YNR029C YNR029C similarity to P.denitrificans cobW protein YNR032C-A HUB1 weak similarity to ubiquitin-like proteins YNR034W-A YNR034W-A hypothetical protein YNR040W YNR040W hypothetical protein YNR042W YNR042W hypothetical protein YNR046W YNR046W strong similarity to S.pombe hypothetical protein SPAC31A2.02 YNR048W YNR048W strong similarity to YCR094w and YNL323w YNR051C BRE5 weak similarity to chicken nucleolin YNR053C NOG2 strong similarity to human breast tumor associated autoantigen YNR054C YNR054C similarity to C.elegans hypothetical protein CEESL47F YNR061C YNR061C weak similarity to hypothetical protein YDL218w YNR062C YNR062C weak similarity to H.influenzae L-lactate permease (lctP) homolog YNR064C YNR064C similarity to R.capsulatus 1-chloroalkane halidohydrolase YNR065C YNR065C strong similarity to YJL222w, YIL173w and PEP1P YNR066C YNR066C strong similarity to PEP1P YNR068C YNR068C similarity to BUL1P YNR074C YNR074C weak similarity to B.subtilis nitrite reductase (nirB) YNR075W COS10 strong similarity to subtelomeric encoded proteins YNR077C YNR077C strong similarity to subtelomeric encoded proteins YOL002C YOL002C strong similarity to YDR492w and S.pombe hypothetical protein YOL003C YOL003C similarity to C.elegans hypothetical protein, YDR126w, YNL326c and YLR246w YOL008W YOL008W similarity to hypothetical protein S. pombe YOL013W-A YOL013W-A questionable ORF - identified by SAGE YOL013W-B YOL013W-B questionable ORF - identified by SAGE YOL014W YOL014W hypothetical protein YOL015W YOL015W weak similarity to YKR015c YOL017W YOL017W similarity to YFR013w YOL019W TOS7 similarity to RIM9P and YFR012w YOL022C YOL022C weak similarity to rat apoptosis protein RP-8 YOL024W YOL024W hypothetical protein YOL026C YOL026C hypothetical protein YOL027C YOL027C similarity to YPR125w YOL029C YOL029C hypothetical protein YOL032W YOL032W weak similarity to hypothetical protein S. pombe YOL035C YOL035C questionable ORF YOL036W YOL036W weak similarity to YMR317w YOL037C YOL037C questionable ORF YOL038C-A YOL038C-A hypothetical protein - identified by SAGE YOL041C NOP12 weak similarity to M.sativa NUM1, hnRNP protein from C. tentans and D. melanogaster, murine/bovine poly(A) binding protein II, and NSR1P YOL045W YOL045W similarity to ser/thr protein kinase YOL046C YOL046C questionable ORF YOL047C YOL047C weak similarity to hypothetical proteins YAL018c and YOL048c YOL048C YOL048C similarity to YAL018c and YOL047c YOL050C YOL050C questionable ORF YOL053W YOL053W hypothetical protein YOL054W YOL054W weak similarity to transcription factors YOL057W YOL057W similarity to hypothetical C. elegans protein F02E9.6 YOL060C AMI3 similarity to hypothetical C.elegans and A.thaliana proteins YOL063C YOL063C hypothetical protein YOL070C YOL070C hypothetical protein YOL071W YOL071W similarity to hypothetical S. pombe protein YOL072W THP1 weak similarity to hypothetical protein C. elegans YOL073C YOL073C weak similarity to hypothetical protein S. pombe YOL077C BRX1 strong similarity to C.elegans K12H4.3 protein YOL078W YOL078W similarity to stress activated MAP kinase interacting protein S. pombe YOL082W CVT19 similarity to YOL083w YOL083W YOL083W similarity to YOL082w YOL084W PHM7 similarity to A.thaliana hyp1 protein YOL085C YOL085C hypothetical protein YOL086W-A YOL086W-A similarity to S. bayanus YOL087C YOL087C similarity to S.pombe hypothetical protein YOL092W YOL092W strong similarity to YBR147w YOL093W YOL093W similarity to C.elegans hypothetical protein F25H8.1 YOL098C YOL098C similarity to hypothetical S.pombe protein YOL099C YOL099C questionable ORF YOL100W PKH2 similarity to ser/thr protein kinases YOL101C YOL101C similarity to YOL002c and YDR492w YOL106W YOL106W questionable ORF - identified by SAGE YOL107W YOL107W weak similarity to human PL6 protein YOL112W MSB4 similarity to Mic1p and human transforming protein tre-2 YOL114C YOL114C similarity to human DS-1 protein YOL117W YOL117W weak similarity to human sodium channel alpha chain HBA YOL118C YOL118C hypothetical protein YOL124C YOL124C weak similarity to M.jannaschii hypothetical protein YOL125W YOL125W similarity to hypothetical protein D. melanogaster YOL128C YOL128C strong similarity to protein kinase MCK1P YOL129W YOL129W similarity to hypothetical S. pombe protein YOL131W YOL131W hypothetical protein YOL134C YOL134C questionable ORF YOL137W YOL137W weak similarity to tetracycline resistance proteins YOL138C YOL138C weak similarity to hypothetical trp-asp repeats containing protein S. pombe YOL146W YOL146W weak similarity to hypothetical protein S. pombe YOL150C YOL150C questionable ORF YOL154W YOL154W similarity to S.fumigata Asp FII YOL155C YOL155C similarity to glucan 1,4-alpha-glucosidase Sta1p and YAR066w YOL159C YOL159C hypothetical protein YOL159C-A YOL159C-A similarity to S. bayanus YOL160W YOL160W hypothetical protein YOL162W YOL162W strong similarity to hypothetical protein YIL166c YOL166C YOL166C hypothetical protein YOR001W RRP6 similarity to human nucleolar 100K polymyositis-scleroderma protein YOR004W YOR004W weak similarity to hypothetical protein YDR339c YOR006C YOR006C similarity to M.jannaschii hypothetical protein MJ0708 YOR007C SGT2 similarity to protein phosphatases YOR008W-B YOR008W-B similarity to S. bayanus YOR012W YOR012W similarity to YDR391c YOR013W YOR013W strong similarity to YDR391c YOR015W YOR015W hypothetical protein YOR019W YOR019W similarity to YDR474c YOR021C YOR021C similarity to Pyrococcus horikoshii hypothetical protein PHBQ041 YOR022C YOR022C weak similarity to D.melanogaster probable Ca2+ transporter rdgB YOR024W YOR024W hypothetical protein YOR029W YOR029W hypothetical protein YOR041C YOR041C questionable ORF YOR042W YOR042W weak similarity to YDR273w YOR044W YOR044W weak similarity to YDR275w YOR049C YOR049C similarity to YER185w, RTA1P YOR050C YOR050C hypothetical protein YOR051C YOR051C weak similarity to myosin heavy chain proteins YOR052C YOR052C similarity to hypothetical protein S. pombe YOR053W YOR053W similarity to protamines YOR055W YOR055W questionable ORF YOR056C YOR056C weak similarity to human phosphorylation regulatory protein HP-10 YOR059C YOR059C weak similarity to YGL144c YOR060C YOR060C hypothetical protein YOR062C YOR062C strong similarity to YKR075c YOR066W YOR066W hypothetical protein YOR068C YOR068C hypothetical protein YOR072W YOR072W hypothetical protein YOR073W YOR073W hypothetical protein YOR078W BUD21 weak similarity to YMR172w YOR080W DIA2 weak similarity to TRCDSEMBL:RNRNAHOP_1 Rattus norvegicus mRNA for Hsp70/Hsp90 organizing protein YOR081C YOR081C strong similarity to YKR089c YOR082C YOR082C questionable ORF YOR083W YOR083W weak similarity to YKR091w YOR084W YOR084W hypothetical protein YOR086C YOR086C weak similarity to synaptogamines YOR087W YOR087W hypothetical protein YOR088W YOR088W weak similarity to human calcium influx channel YOR091W YOR091W similarity to hypothetical S.pombe protein D83992_G YOR093C YOR093C similarity to S.pombe hypothetical protein SPAC22F3.04 YOR097C YOR097C hypothetical protein YOR102W YOR102W questionable ORF YOR104W PIN2 hypothetical protein YOR105W YOR105W questionable ORF YOR111W YOR111W weak similarity to B.subtilis maf protein YOR112W YOR112W similarity to C.elegans hypothetical protein YOR114W YOR114W hypothetical protein YOR118W YOR118W similarity to PIR:T39884 hypothetical protein SPBC21.02 S. pombe YOR119C RIO1 similarity to a C.elegans ZK632.3 protein YOR121C YOR121C questionable ORF YOR129C YOR129C weak similarity to hypothetical protein SPBC776.06c S. pombe YOR131C YOR131C weak similarity to E.coli hypothetical 27K protein YOR135C YOR135C questionable ORF YOR137C YOR137C similarity to YLR361c YOR138C YOR138C weak similarity to TRCDSEMBL:AF175293_2 gene: vanSD sensor protein kinase Enterococcus faecium strain vanD glycopeptide resistance gene cluster YOR139C YOR139C questionable ORF YOR144C EFD1 weak similarity to human DNA-binding protein PO-GA and to bacterial H+-transporting ATP synthases YOR145C YOR145C strong similarity to hypothtical S. pombe protein and to hypothetical C. elegans protein YOR146W YOR146W questionable ORF YOR147W YOR147W similarity to YHR194w YOR152C YOR152C hypothetical protein YOR154W YOR154W similarity to hypothetical A. thaliana proteins F19G10.15 and T19F06.21 YOR155C YOR155C similarity to 5'-flanking region of the Pichia MOX gene YOR161C YOR161C similarity to C.elegans cosmid F35C8 YOR164C YOR164C similarity to conserved hypothetical protein S. pombe YOR166C YOR166C similarity to PIR:T50422 hypothetical protein S. pombe YOR169C YOR169C questionable ORF YOR170W YOR170W questionable ORF YOR172W YOR172W similarity to finger protein YKL222c, YOR162c and YLR266c YOR173W YOR173W strong similarity to YLR270w YOR175C YOR175C similarity to human and murine C3f protein YOR183W FYV12 hypothetical protein YOR186W YOR186W hypothetical protein YOR189W IES4 weak similarity to chicken nonhistone chromosomal protein HMG-2 YOR191W RIS1 similarity to RAD5 protein YOR193W YOR193W weak similarity to YPL112c YOR197W YOR197W strong similarity to hypothetical protein SPCC1840.04 S. pombe YOR199W YOR199W questionable ORF YOR200W YOR200W questionable ORF YOR203W YOR203W questionable ORF YOR205C YOR205C hypothetical protein YOR214C YOR214C hypothetical protein YOR215C YOR215C similarity to M.xanthus hypothetical protein YOR218C YOR218C questionable ORF YOR220W YOR220W hypothetical protein YOR223W YOR223W hypothetical protein YOR225W YOR225W questionable ORF YOR228C YOR228C weak similarity to YNR013c YOR235W YOR235W questionable ORF YOR238W YOR238W similarity to hypothetical S. pombe protein YOR239W (ABP140) questionable ORF YOR240W YOR240W similarity to C.elegans ZK1058.5 protein YOR242C SSP2 weak similarity to M.pneumoniae probable ABC transport permease YOR243C YOR243C similarity to M.jannaschii hypothetical protein MJ0588 YOR245C DGA1 similarity to hypothetical C. elegans proteins YOR248W TOS11 hypothetical protein YOR252W YOR252W hypothetical protein YOR253W YOR253W weak similarity to 'separation anxiety protein-like'; A. thaliana YOR255W YOR255W hypothetical protein YOR258W HNT3 similarity to hypothetical protein SPCC18.09c S. pombe YOR262W YOR262W similarity to YLR243w YOR263C YOR263C questionable ORF YOR264W YOR264W hypothetical protein YOR267C YOR267C similarity to ser/thr protein kinases YOR268C YOR268C hypothetical protein YOR269W PAC1 similarity to human LIS-1 protein YOR275C YOR275C similarity to A.nidulans palA protein YOR277C YOR277C questionable ORF YOR279C YOR279C hypothetical protein YOR282W YOR282W questionable ORF YOR284W YOR284W weak similarity to M.jannaschii hypothetical protein MJ0694 YOR287C YOR287C weak similarity to PITSLRE protein kinase isoforms YOR289W YOR289W similarity to C.elegans hypothetical protein YOR292C YOR292C similarity to human and mouse glomerulosclerosis protein Mpv17 YOR296W YOR296W similarity to hypothetical S. pombe protein YOR300W YOR300W questionable ORF YOR305W YOR305W weak similarity to hypothetical protein SPAC824.03c S. pombe YOR309C YOR309C questionable ORF YOR311C HSD1 similarity to hypothetical S. pombe protein YOR314W YOR314W hypothetical protein YOR314W-A YOR314W-A similarity to S. bayanus YOR315W YOR315W hypothetical protein YOR318C YOR318C hypothetical protein YOR320C YOR320C similarity to GNT1 alphaN-acetylglucosamine transferase K. lactis YOR322C YOR322C similarity to hypothetical S.pombe protein SPAC1F12.05 YOR324C YOR324C similarity to YAL028w YOR325W YOR325W questionable ORF YOR331C YOR331C questionable ORF YOR333C YOR333C questionable ORF YOR338W YOR338W similarity to YAL034c YOR342C YOR342C weak similarity to YAl037w YOR343C YOR343C hypothetical protein YOR345C YOR345C questionable ORF YOR350C MNE1 weak similarity to ESP1P and mitochondrial L.illustris cytochrome oxidase I YOR352W YOR352W hypothetical protein YOR353C YOR353C weak similarity to adenylate cyclases YOR354C MSC6 weak similarity to genomic sequence for A. thaliana YOR359W YOR359W similarity to hypothetical protein Ca49C10.19 Candida albicans YOR364W YOR364W hypothetical protein YOR365C YOR365C strong similarity to YAL053w YOR366W YOR366W questionable ORF YOR371C GPE1 similarity to YAL056w YOR376W YOR376W hypothetical protein YOR379C YOR379C questionable ORF YOR380W YOR380W weak similarity to PDR3P YOR382W FIT2 hypothetical protein YOR385W YOR385W strong similarity to hypothetical protein YMR316w YOR387C YOR387C strong similarity to YGL258w YOR389W YOR389W strong similarity to putative pseudogenes YPL277c and YPL278c YOR390W YOR390W strong similarity to YPL279c YOR391C YOR391C strong similarity to YMR322c and YDR533c, identical to YPL280w YOR392W YOR392W hypothetical protein YOR394W YOR394W strong similarity to members of the SRP1P/TIP1P family YPL004C YPL004C strong similarity to YGR086c YPL005W YPL005W weak similarity to NUP2P YPL009C YPL009C similarity to M.jannaschii hypothetical protein YPL012W RRP12 hypothetical protein YPL014W YPL014W hypothetical protein YPL025C YPL025C questionable ORF YPL027W SMA1 hypothetical protein YPL030W YPL030W similarity to C.elegans hypothetical protein YPL033C YPL033C weak similarity to YLR426w YPL034W YPL034W questionable ORF YPL035C YPL035C questionable ORF YPL039W YPL039W hypothetical protein YPL041C YPL041C hypothetical protein YPL044C YPL044C questionable ORF YPL047W YPL047W weak similarity to A. thaliana genomic DNA YPL052W YPL052W hypothetical protein YPL054W LEE1 similarity to S. pombe scp3/SPAC3A11.02 spindle poison sensitivity related protein YPL055C YPL055C hypothetical protein YPL056C YPL056C hypothetical protein YPL062W YPL062W hypothetical protein YPL063W YPL063W similarity to hypothetical protein YLR019w, YLL010c and S.pombe hypothetical protein SPAC2F7.02c YPL064C YPL064C weak similarity to S.pombe peptidyl-prolyl cis-trans isomerase YPL066W YPL066W hypothetical protein YPL067C YPL067C hypothetical protein YPL068C YPL068C hypothetical protein YPL070W YPL070W weak similarity to VPS9P YPL071C YPL071C hypothetical protein YPL073C YPL073C questionable ORF YPL077C YPL077C weak similarity to YBR197c YPL080C YPL080C hypothetical protein YPL093W NOG1 similarity to M.jannaschii GTP-binding protein YPL095C YPL095C strong similarity to YBR177c YPL098C YPL098C similarity to S.pombe hypothetical protein YPL099C YPL099C weak similarity to Sulfolobus hypothetical protein YPL100W YPL100W similarity to YFR021w YPL102C KRE24 questionable ORF YPL103C YPL103C similarity to hypothetical M. tuberculosis protein YPL107W YPL107W similarity to hypothetical protein SPCP31B10.02 S. pombe YPL108W YPL108W hypothetical protein YPL110C YPL110C similarity to C.elegans hypothetical protein, weak similarity to PHO81P YPL112C YPL112C weak similarity to YOR193w YPL114W YPL114W questionable ORF YPL130W SPO19 hypothetical protein - putative glycophosphatidylinositol (GPI)-anchored spore wall protein YPL136W YPL136W questionable ORF YPL137C YPL137C similarity to microtubule-interacting protein MHP1P and to hypothetical protein YOR227w YPL138C SPP1 weak similarity to fruit fly polycomblike nuclear protein YPL141C YPL141C strong similarity to protein kinase KIN4P YPL142C YPL142C questionable ORF YPL144W YPL144W hypothetical protein YPL146C YPL146C weak similarity to myosin heavy chain proteins YPL150W YPL150W similarity to ser/thr protein kinases YPL151C PRP46 strong similarity to A.thaliana PRL1 and PRL2 proteins YPL152W RRD2 strong similarity to human phosphotyrosyl phosphatase activator YPL156C PRM4 weak similarity to YDL010w YPL157W YPL157W weak similarity to S.pombe hypothetical protein SPAC2G11.15c YPL158C YPL158C weak similarity to human nucleolin YPL159C YPL159C weak similarity to YPR151c YPL162C YPL162C weak similarity to hypothetical protein B14D6.530 S. pombe YPL165C YPL165C weak similarity to YHR207c YPL166W YPL166W weak similarity to paramyosins YPL168W YPL168W weak similarity to E.coli bfpB protein YPL170W YPL170W similarity to C.elegans LIM homeobox protein YPL180W SHD7 weak similarity to human l-caldesmon I YPL181W YPL181W weak similarity to YKR029c YPL182C YPL182C questionable ORF YPL183C YPL183C similarity to TAF90P YPL184C YPL184C weak similarity to PUB1P YPL185W YPL185W questionable ORF YPL186C YPL186C weak similarity to Xenopus protein xlgv7 YPL188W POS5 similarity to UTR1P and YEL041w YPL191C YPL191C strong similarity to YGL082w YPL192C PRM3 hypothetical protein YPL196W OXR1 weak similarity to S.pombe hypothetical protein SPAC8C9 YPL197C YPL197C questionable ORF YPL199C YPL199C weak similarity to T.cruzi p284 protein YPL200W CSM4 hypothetical protein YPL201C YPL201C hypothetical protein YPL202C AFT2 similarity to cell size regulation protein RCS1P YPL205C YPL205C questionable ORF YPL206C YPL206C weak similarity to glycerophosphoryl diester phosphodiesterases YPL207W YPL207W similarity to hypthetical proteins from A. fulgidus, M. thermoautotrophicum and M. jannaschii YPL208W YPL208W similarity to YHL039w YPL216W YPL216W similarity to YGL133w YPL221W BOP1 strong similarity to YGL139w and YAL053w YPL222W YPL222W similarity to C.perfringens hypothetical protein YPL225W YPL225W strong similarity to hypothetical protein SPBC3E7.07c S. pombe YPL229W YPL229W weak similarity to YMR181c YPL233W YPL233W weak similarity to hypothetical protein S. pombe YPL238C YPL238C questionable ORF YPL244C HUT1 weak similarity to human UDP-galactose transporter related isozyme 1 YPL245W YPL245W weak similarity to human mutL protein homolog YPL246C YPL246C weak similarity to mouse proteinase activated receptor 2 YPL247C YPL247C similarity to human HAN11 protein and petunia an11 protein YPL249C GYP5 similarity to mouse Tbc1 protein YPL250C ICY2 weak similarity to YMR195w YPL251W YPL251W questionable ORF YPL253C VIK1 similarity to CIK1P YPL257W YPL257W weak similarity to YIL029c YPL258C THI21 similarity to B.subtilis transcriptional activator tenA, and strong similarity to hypothetical proteins YOL055c and YPR121w YPL260W YPL260W similarity to hypothetical protein SPAC30C2.08 S.pombe YPL261C YPL261C questionable ORF YPL263C KEL3 similarity to KEL2P and KEL1P YPL264C YPL264C strong similarity to YMR253c YPL267W YPL267W weak similarity to C.elegans transcription factor unc-86 YPL272C YPL272C hypothetical protein YPL273W SAM4 strong similarity to YLL062c YPL277C YPL277C strong similarity to hypothetical protein YOR389w/putative pseudogene YPL278C YPL278C strong similarity to hypothetical protein YOR389w/putative pseudogene YPL279C YPL279C strong similarity, nearly identical to YOR390w YPL280W YPL280W strong similarity to YMR322c and YDR533c YPL282C YPL282C strong similarity to subtelomeric encoded proteins YPL283C YRF1-7 strong similarity to subtelomeric encoded proteins YPR002C-A YPR002C-A questionable ORF - identified by SAGE YPR002W PDH1 similarity to B.subtilis mmgE protein YPR012W YPR012W hypothetical protein YPR014C YPR014C hypothetical protein YPR016W-A YPR016W-A similarity to S. bayanus YPR022C YPR022C weak similarity to fruit fly dorsal protein and SNF5P YPR023C EAF3 similarity to human hypothetical protein YPR027C YPR027C similarity to YNL019c and YNL033w YPR030W CSR2 similarity to YBL101c YPR038W YPR038W questionable ORF YPR039W YPR039W questionable ORF YPR040W SDF1 similarity to C.elegans C02C2.6 protein YPR044C YPR044C questionable ORF YPR049C CVT9 similarity to USO1P YPR050C YPR050C questionable ORF YPR053C YPR053C questionable ORF YPR059C YPR059C questionable ORF YPR061C YPR061C weak similarity to Synechococcus sp. DnaJ protein YPR063C YPR063C hypothetical protein YPR064W YPR064W hypothetical protein YPR071W YPR071W strong similarity to YIL029c YPR074W-A YPR074W-A similarity to S. bayanus YPR076W YPR076W questionable ORF YPR077C YPR077C questionable ORF YPR078C YPR078C hypothetical protein YPR079W MRL1 weak similarity to human insulin-like growth factor 2 receptor YPR083W YPR083W hypothetical protein YPR084W YPR084W hypothetical protein YPR085C YPR085C hypothetical protein YPR087W YPR087W questionable ORF YPR089W YPR089W questionable ORF YPR090W YPR090W weak similarity to hypothetical protein SPAC25B8.08 S. pombe YPR091C YPR091C weak similarity to C.elegans LIM homeobox protein YPR092W YPR092W questionable ORF YPR093C YPR093C weak similarity to zinc-finger proteins YPR094W YPR094W weak similarity to chicken lim-3 protein YPR096C YPR096C hypothetical protein YPR097W YPR097W similarity to hypothetical protein SPCC1450.12 S. pombe YPR098C YPR098C hypothetical protein YPR099C YPR099C questionable ORF YPR100W YPR100W weak similarity to C.elegans hypothetical protein CEC25A1 YPR105C COD1 similarity to hypothetical protein SPCC338.13 S. pombe YPR109W YPR109W weak similarity to human nicotinic acetylcholine receptor delta chain YPR114W YPR114W similarity to YJR116w YPR116W YPR116W hypothetical protein YPR117W YPR117W similarity to YLR454w YPR118W YPR118W similarity to M.jannaschii translation initiation factor, eIF-2B YPR121W THI22 similarity to B.subtilis transcriptional activator tenA YPR123C YPR123C questionable ORF YPR126C YPR126C questionable ORF YPR127W YPR127W similarity to C-term. of N.tabacum auxin-induced protein YPR128C ANT1 peroxisomal ATP carrier YPR130C YPR130C questionable ORF YPR136C FYV15 questionable ORF YPR139C YPR139C weak similarity to nGAP H. sapiens nGAP mRNA YPR142C YPR142C questionable ORF YPR143W YPR143W hypothetical protein YPR144C YPR144C similarity to YDR060w and C.elegans hypothetical protein YPR146C YPR146C questionable ORF YPR147C YPR147C weak similarity to CG9186 D. melanogaster YPR148C YPR148C weak similarity to hypothetical protein S. pombe YPR150W YPR150W questionable ORF YPR151C YPR151C weak similarity to YPL159c YPR152C YPR152C weak similarity to hypothetical protein CG3542 D. melanogaster YPR153W YPR153W hypothetical protein YPR154W PIN3 similarity to chicken growth factor receptor-binding protein GRB2 homolog YPR157W YPR157W strong similarity to YGR141w YPR158W YPR158W similarity to YGR142w YPR169W YPR169W weak similarity to hypothetical protein SPAC1A6.02 S. pombe YPR170C YPR170C hypothetical protein YPR170W-A YPR170W-A hypothetical protein - identified by SAGE YPR171W YPR171W hypothetical protein YPR172W YPR172W strong similarity to YLR456w YPR174C YPR174C weak similarity to NBP1P YPR177C YPR177C questionable ORF YPR179C PLO1 similarity to PLO2P, weak similarity to C-terminal region of Nip80p YPR195C YPR195C hypothetical protein YPR197C YPR197C questionable ORF YPR202W YPR202W strong similarity to subtelomeric encoded proteins YPR203W YPR203W strong similarity to subtelomeric encoded proteins YPR204W YPR204W strong similarity to subtelomeric encoded proteins Q0010 Q0010 similarity to Sauroleishmania NADH dehydrogenase (ubiquinone) chain 5 Q0017 Q0017 questionable ORF Q0032 Q0032 questionable ORF Q0092 Q0092 questionable ORF Q0142 Q0142 questionable ORF Q0143 Q0143 questionable ORF Q0144 Q0144 questionable ORF Q0182 Q0182 questionable ORF Q0297 Q0297 questionable ORF