## MAPK-DKPP ##
# The distributed kinase and processive phosphotase version of the MAP
# kinase model

% Compartments MAPK-DKPP
# There is no volume in this model, using 1 for volume
v	3	1

% Seeds
S 2
P 1

% Inputs v
E   1

% States v
S	S
E:S	0
M	0
E:M	0
D	0
P	P
P:D	0
P:M	0

% Outputs
S	S
M	M
D	D

% Parameters
k1on	0.02
k1off	1
k1cat	0.01
k2on	0.032
k2off	1
k2cat	15
k3on	0.045
k3off	1
k3cat	0.092
k4cat	0.5

% Reactions
E   S   E:S 0   k1on    k1off   E_+_S_<->_ES
E:S 0   E   M   k1cat   0       ES_->_E_+_M
E	M   E:M	0   k2on    k2off   E_+_M_<->_EM
E:M 0   E   D   k2cat   0       EM_->_E_+_D
P   D   P:D 0   k3on    k3off   P_+_D_<->_PD
P:D 0   P:M 0   k3cat   0       PD_->_PM
P:M 0   P   S   k4cat   0       PM_->_P_+_S