Title(s): Executive Director for the MIT Synthetic Biology Center;
Research Scientist-Architect in the Weiss Lab
Affiliated lab(s): Weiss Lab
Organize with colleagues a multi-disciplined initiative to:
1) Apply systems biology, synthetic biology and genome design engineering to reverse the six decade decline in the productivity of the pharmaceutical industry R&D/Manufacturing value chain.
2) Change the innovation economics of post-genomic medicines to behave like Moore’s Law, thereby both exponentially decreasing cost and increasing demand, just as semiconductor-based computer products have been doing for four decades.
3) Expand drug accessibility and affordability on a global scale through philanthropic, governmental and commercial market-driven means.
Six billion out of seven billion people on the planet now have cell phones, and soon will have smartphones and handheld computers.
What’s preventing us from doing the same for life-saving drugs?
My Favorite Things:
Ligands on targets and returns on investments
Solar collectors and downtown developments
Jazz musicians playing with improvised rhythms
Embryos in a dish dancing with genetic algorithms
Wet paint on canvas and facades on skyscrapers
Manuscript drafts and peer reviewed papers
Evolution stumbling through infinite sequence space
Emergent human consciousness quickening the pace
In carbo instantiations of in silico dreams
The passage of time recorded in genomic slipstreams
White cathedrals with high vaulted ceilings
Young lovers embracing with ancient feelings
Pre-competitive consortia inspired by game theories
Gibson DNA assemblies and database queries
Proteins, circuits, drug targets and genes
These are a few of my favorite things.
When sickness strikes
When I think and say negative memes
When I’m feeling sad
I simply remember my favorite things
And then I don’t feel so bad.
(apologies to Rodgers and Hammerstein)